Digital Commons Network^™

Impact Of Required Antibiotic Stop Dates And Indications On Length Of Treatment In Hospitalized Patients With Pneumonia, Amanda Haddad, Kathryn Hernando, Kayihura Manigaba, Abigail Antigua

Infectious Disease

Purpose: The CDC Core Elements of Hospital Antibiotic Stewardship Programs recommends implementing policies to support optimal antibiotic prescribing including documentation of dose, duration and indication. On January 31, 2017, the study institution implemented new physician order entry screens in the electronic health record requiring the input of indication and duration on all antibiotic orders. The objective of this study is to determine if implementation of mandatory indication and duration for antibiotic orders decreases antibiotic duration of therapy in hospitalized patients with pneumonia.

Methods: This study was submitted to the Institutional Review Committee for approval. The clinical pharmacy surveillance platform, …

Impact Of Methicillin-Resistant Staphylococcus Aureus (Mrsa) Nasal Swab On Total Duration Of Mrsa Therapy For Pneumonia Patients, Darren D. Yum, Kayihura Manigaba, Danielle Gagne, Heather Ellis

Infectious Disease

Purpose: Recent literature has highlighted MRSA nasal screening as a possible antimicrobial stewardship program tool for avoiding unnecessary empiric anti-MRSA therapy for pneumonia. MRSA is an important cause of pneumonia and clinicians must determine when empiric antimicrobial therapy directed toward this pathogen is needed. Negative MRSA nasal swab has been shown to have a high negative predictive value ( >95%) across different types of pneumonia. The objective of this study is to assess the impact of negative MRSA nasal swabs on the duration of anti-MRSA therapy in a community hospital setting.

Methods: This study will be submitted to the institutional …

Postpartum Endometritis And Infection Following Incomplete Or Complete Abortion: Case Definition & Guidelines For Data Collection, Analysis, And Presentation Of Maternal Immunization Safety Data, C E. Rouse, L O. Eckert, F M. Muñoz, J S A. Stringer, S Kochhar, L Bartlett, M Sanicas, D J. Dudley, D M. Harper, Fyezah Jehan

Department of Paediatrics and Child Health

Abstract are not provided by the author/publisher

Mosquito-Borne Illnesses And Their Disproportionate Impact On Variant Infrastructures: A Gis Map Comparison Of Three Regions., Jenna N. Price

Honors Theses

Mosquitoes are the deadliest animals on earth and they spread diseases through their bites. Chikungunya, Dengue, Malaria, Yellow Fever, West Nile Virus, and Zika are six diseases of concern that are transmitted by mosquitoes. This honors thesis will attempt to provide relevant information and a critical analysis of current literature. Disease descriptions of the aforementioned illnesses and country evaluations for Niger, South Sudan, and the United States of America are included for comparison and evaluation. A Geographic Information System was used to create several maps comparing the three regions of the earth specified. The models are used to show country …

Anantharamaiah Named To National Academy Of Inventors, Alicia Rohan

Browse All News

No abstract provided.

Bjc Today

BJC Today

No abstract provided.

Integrating Patient Safety In Nursing Education: An Analysis Of Pre-Registration Nursing Curricula In Kenya, Nickcy Nyaruai Mbuthia

Dissertations

The purpose of this research was to investigate the extent to which patient safety concepts were integrated in the Kenyan pre-registration Bachelor of Science in nursing curriculum, and to understand the issues that influence its delivery in the classroom and clinical settings, with the aim of developing strategies that will enhance the integration of patient safety concepts in the curriculum. In the first phase, a qualitative content analysis of the nursing curriculum documents was performed.

Happy Feet In A Rural Clinic: A Diabetic Foot Education Intervention, Carmencita S. Abood

Dissertations

Rural Healthy People 2010 report indicated that diabetes was more pervasive in non-metropolitan areas than in central cities and more commonplace in the Southeast and the Southwest regions of the United States due to complex set of factors such as low socioeconomic status among many rural residents, a high proportion of racial or ethnic minorities, and aging populations that were predominant in rural areas. The need for innovative, low literacy education material that type 2 diabetes mellitus (T2DM) patients in a rural clinic is imperative. The purpose of the capstone project was to determine the effectiveness of a patient-centered diabetes …

Mapping Careful Epidemiology: Spatialities, Materialities And Subjectivities In The Management Of Animal Disease., Gareth Enticott, Kim Ward

School of Geography, Earth and Environmental Sciences

No abstract provided.

Editorial Board

Karbala International Journal of Modern Science

No abstract provided.

Outbreak Of Ebola Virus Disease, Alexandra Dimit, Tiffany Kneuss, Joelle Farano, Haley Armstrong, Jodi Otte, Andrew M. Roecker

Pharmacy and Wellness Review

Ebola virus disease (EVD) has existed as a major health concern with devastating and, many times, fatal symptoms. The recent outbreaks of EVD in West Africa and the Democratic Republic of the Congo (DRC) have incited international concern. In this article, the implications of EVD will be discussed including the etiology, transmission, signs and symptoms, diagnosis and treatment of the disease. In addition to this discussion, the manner in which major health care organizations, including the World Health Organization (WHO), are dealing with treating infected patients and containing spread of the disease will be covered.

Recent Advances Spark Significant Guideline Change: Antiretroviral Therapy (Art) At High Cd4+ Counts In The Treatment Naïve Patient, Joshua Ilenin, Kelly Fargo, Lisa Berni, Kristen Thatcher, Caitlin Swann, Andrew Roecker

Pharmacy and Wellness Review

Human immunodeficiency virus (HIV) targets CD4+ lymphocytes, a critical component to proper functioning of the human immune system. HIV is a significant public health concern, having resulted in over 27 million deaths since its discovery. Currently, several different treatment options exist, with combination antiretroviral therapy (ART) at the forefront. Despite the success of ART therapy, there are number of problems, including poor patient compliance. Due to this, the appropriate time to initiate therapy in the treatment naïve patient is under continuous scrutiny. Recently, several trials have demonstrated evidence suggesting that initiating ART at high CD4+ counts in the treatment naïve …

Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 3.0., Eric W Deutsch, Lydie Lane, Christopher M Overall, Nuno Bandeira, Mark S Baker, Charles Pineau, Robert L Moritz, Fernando Corrales, Sandra Orchard, Jennifer E Van Eyk, Young-Ki Paik, Susan T Weintraub, Yves Vandenbrouck, Gilbert S Omenn

Articles, Abstracts, and Reports

The Human Proteome Organization's (HUPO) Human Proteome Project (HPP) developed Mass Spectrometry (MS) Data Interpretation Guidelines that have been applied since 2016. These guidelines have helped ensure that the emerging draft of the complete human proteome is highly accurate and with low numbers of false-positive protein identifications. Here, we describe an update to these guidelines based on consensus-reaching discussions with the wider HPP community over the past year. The revised 3.0 guidelines address several major and minor identified gaps. We have added guidelines for emerging data independent acquisition (DIA) MS workflows and for use of the new Universal Spectrum Identifier …

Deworming Children For Soil-Transmitted Helminths In Low And Middle-Income Countries: Systematic Review And Individual Participant Data Network Meta-Analysis, Vivian Andrea Welch, Alomgir Hossain, Elizabeth Ghogomu, Alison Riddle, Simon Cousens, Michelle Gaffey, Paul Arora, Robert Black, Donald Bundy, Zulfiqar Ahmed Bhutta

Woman and Child Health

Intestinal parasites affect millions of children globally. We aimed to assess effects of deworming children on nutritional and cognitive outcomes across potential effect modifiers using individual participant data (IPD). We searched multiple databases to 27 March 2018, grey literature, and other sources. We included randomised and quasi randomised trials of deworming compared to placebo or other nutritional interventions with data on baseline infection. We used a random-effects network meta-analysis with IPD and assessed overall quality, following a pre-specified protocol. We received IPD from 19 trials of STH deworming. Overall risk of bias was low. There were no statistically significant subgroup …

Novel Bacterial Vaginosis-Associated Organisms Mediate The Relationship Between Vaginal Douching And Pelvic Inflammatory Disease, Tamala Gondwe, Roberta Ness, Patricia A. Totten, Sabina Astete, Gong Tang, Melanie A. Gold, David Martin, Catherine L. Haggerty

School of Medicine Faculty Publications

Objectives: We sought to determine whether the relationship between a history of vaginal douching and pelvic inflammatory disease (PID) is mediated by endometrial infection with one or more novel bacterial vaginosis (BV)-associated organisms among Atopobium vaginae, the BV-associated bacterium 1 (BVAB1), neathia (Leptotrichia) amnionii and Sneathia sanguinegens. Methods: We first conducted log-binomial regression analyses to identify risk factors for endometrial infection in 535 adolescent and adult women with clinically suspected PID in the PID Evaluation and Clinical Health (PEACH) study. We then examined whether endometrial infection by the BV-associated organisms mediated the association between a history of vaginal douching and …

Concurrent Discitis And A Spinal Epidural Abscess Following Transforaminal Epidural Steroid Injection Arising From An Unlikely Bacterial Species, Adlai Pappy Ii, Vinita Singh Md

Anesthesiology

No abstract provided.

Efficiency Fast-Moving Drug Plan With Reorder Point Intervention At A Private Hospital In Bandung, Aisha K. Nur, Angga P. Kautsar, Indah L. Hilmi, Rizky Abdulah

Pharmacology and Clinical Pharmacy Research

Drug supplies are the major portion of the hospital expenses. The rising of drugs cost directly affect the total expenses of the hospital. Thus, their procurement, especially for fast-moving drugs, should be managed effectively. This study aimed to examine the efficiency of fast-moving drug plan after reorder point (ROP) intervention at a private hospital in Bandung. We conducted a pre-experimental study and used turn-over ratio (TOR) as a parameter. Data were taken from the stock of antibiotics in May-June of 2013 and May-June 2014. Cost components were collected; included the amount of stock, the cost of goods sold, and daily …

Reconstructing Energy Flow Through Modern And Historical Marine Communities: Insights From Amino Acid Isotope Analysis, Emma A. Elliott Smith

Biology ETDs

The fundamental currency of life is energy. Organisms need energy to grow, to survive and to reproduce. Understanding the acquisition of energy by consumers is thus a foundational aspect of biological research. This is especially important in the modern era, as impacts of ongoing anthropogenic effects will be mediated or amplified through food webs. Here, I explore how isotopic analysis of individual amino acids – a technique new to ecological studies – can be used to trace energy flow through animal communities in modern and ancient time periods. In particular, I focus on kelp forest food webs, which are nearshore …

Raising Adult Immunization Rates, Madalyn Schaefgen Md, Barbara Sikora Lpn, Donna Wendling

Department of Family Medicine

No abstract provided.

Urolithiasis Is A Risk Factor For Uroseptic Shock And Acute Kidney Injury In Patients With Urinary Tract Infection., Chih-Yen Hsiao, Tsung-Hsien Chen, Yi-Chien Lee, Meng-Chang Hsiao, Peir-Haur Hung, Yih-Yuan Chen, Ming-Cheng Wang

Faculty Research 2019

Urinary tract infection (UTI) is a common complication in patients with urolithiasis. This study aimed to compare clinical manifestations and treatment outcomes among UTI patients with or without urolithiasis. It also focused on identifying relationships among urolithiasis, uroseptic shock, and acute kidney injury (AKI). This retrospective study enrolled hospitalized UTI patients who underwent imaging in an acute care setting from January 2006 to March 2015. Of 662 participants enrolled, 113 (17.1%) had urolithiasis, 107 (16.2%) developed uroseptic shock, and 184 (27.8%) developed AKI. A multivariate logistic regression analysis showed that in UTI patients, urolithiasis is associated with an increased risk …

Sepsis Screening Tool Increased The Usage Of Sepsis Order Set, Raweewan Liengsawangwong

Applied Research Projects

Introduction: The sepsis screening tool was launched to improve the usage of the sepsis order set.

Objectives: The purposes of this study were to determine whether the sepsis screening tool increased the usage of sepsis order set and whether the tool improved the primary outcomes. This study assessed the association between using sepsis order set and the compliance of the SEP-1 measure (represented by achieving total perfect care), and the primary outcomes. Furthermore, this study assessed association between the compliance with SEP-1 and the primary outcomes. The primary outcomes were a) time zero to antibiotics, b) inpatient length of stay, …

We Are...Marshall, December 4, 2019, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

Volume 57, Number 17: December 04, 2019, University Of North Dakota

University Letter Archive

No abstract provided.

An Overview Of The Health Delivery System In The State Of Mississippi, Cerlyn K. Ellis

Publications and Research

Imagine residing in a high-income country that doesn’t provide access to necessary healthcare. The state of Mississippi remains one of the poorest states in the United States. This has resulted in poor health outcomes and chronic access barriers. Residents of Mississippi ranks poorly in most health indicators, including Infectious Disease, Infant Mortality, Clinic Care, Obesity, Diabetes, and Premature Death.

With half of all rural hospitals in Mississippi threatened with closure, access and quality of care barriers will become more challenging to resolve. This comes partly as a result of the state largely governed by Republicans and the legislators refusing to …

A Shift In Global Thought And Practice: Assessing The Impacts Of The Human Security Paradigm On Global Public Health, Elizabeth Livingston Leone

Honors College Theses

With the increasing emphasis on health through human security since the 1990s by the United Nations, scholars have debated how human security has influenced public health. I examine how the idea of human security has become a paradigm and if this paradigm has adopted in public health programs. I argue that the rise of human security has led to an emphasis on the role of global actors, preventative care and health education when states adopt the paradigm. This adoption should in turn improve public health in Ghana and the Ivory Coast.

Clinical Evaluation Of Functional State Of Immune System Partucular Components In Patients With Opium Addiction, Sh. Kh. Sultanov, Z. Sh. Ashurov, N. I. Khodzhaeva, L. Sh. Shadmanova

Central Asian Journal of Medicine

In this study, a comprehensive research of the phagocytic activity of neutrophils in patients with heroin addiction was carried out. It was found that heroin addiction is accompanied by pronounced changes in the cellular-humoral defense system of the body. Opiate substances have a mainly suppressive effect on immunocompetent cells. The disorganization of the immune systems, which are closely interconnected with the central nervous system, leads to disruption of cellular and humoral homeostasis and aggravates the process of drug addiction. One of the existing hypotheses of the cause of this process is the theory of a decrease in the function of …

The Choice Of Biopreparation For The Correction Of Intestinal Dysbacteriosis In Children With Chronic Hbv Infection And Giardiasis, Nargiza F. Nurmatova, Flora I. Inoyatova, Nargis K. Mirsalikhova, Malohat O. Asilbekova

Central Asian Journal of Medicine

Research objective: to assess efficiency of application of bio preparations in the correction of intestinal dysbacteriosis taking into account the results of “Load” test in vitro in children with chronic hepatitis B together with giardiasis. Material and methods. We examined one hundred and fifty children with chronic hepatitis B (CHB) with concomitant giardiasis in the age from 3 to 18 years old. The diagnosis was based on data from history, results of clinical tests, biochemical and instrumental tests. Laboratory diagnostics of giardiasis was performed using the following methods: immune fluorescent method (G. Lamblia antigen in feces), polymerase chain reaction (G. …

Scientific, Methodological And Organizational Bases Of Management Of The Epidemic Process In Case Of Salmonellous Infection In Uzbekistan, Оmon М. Mirtazayev, Nikolay I. Briko, Gulbakhor S. Matnazarova, Nargiza S. Saidkasimova

Central Asian Journal of Medicine

In the last decade, the epidemiological characteristics of salmonellosis have changed, in particular, the incidence of human disease has increased, and salmonella infection of farm animals, birds and the environment has increased. The increasing epidemiological role of agricultural birds and industrial poultry products, the relationship between epizootic and epidemic processes require the restructuring of the existing system of epidemiological surveillance of salmonellosis under epizootic and epidemiological supervision. On the basis of the results of scientific research, epizoolic-epidemiological supervision of salmonellosis has been developed, in relation to the conditions of Uzbekistan.

Clinical Evaluation Of Functional State Of Immune System Partucular Components In Patients With Opium Addiction, Sh. Kh. Sultanov, Z. Sh. Ashurov, N. I. Khodzhaeva, L. Sh. Shadmanova

Central Asian Journal of Medicine

In this study, a comprehensive research of the phagocytic activity of neutrophils in patients with heroin addiction was carried out. It was found that heroin addiction is accompanied by pronounced changes in the cellular-humoral defense system of the body. Opiate substances have a mainly suppressive effect on immunocompetent cells. The disorganization of the immune systems, which are closely interconnected with the central nervous system, leads to disruption of cellular and humoral homeostasis and aggravates the process of drug addiction. One of the existing hypotheses of the cause of this process is the theory of a decrease in the function of …

Scientific, Methodological And Organizational Bases Of Management Of The Epidemic Process In Case Of Salmonellous Infection In Uzbekistan, Оmon М. Mirtazayev, Nikolay I. Briko, Gulbakhor S. Matnazarova, Nargiza S. Saidkasimova

Central Asian Journal of Medicine

In the last decade, the epidemiological characteristics of salmonellosis have changed, in particular, the incidence of human disease has increased, and salmonella infection of farm animals, birds and the environment has increased. The increasing epidemiological role of agricultural birds and industrial poultry products, the relationship between epizootic and epidemic processes require the restructuring of the existing system of epidemiological surveillance of salmonellosis under epizootic and epidemiological supervision. On the basis of the results of scientific research, epizoolic-epidemiological supervision of salmonellosis has been developed, in relation to the conditions of Uzbekistan.