Digital Commons Network^™

Bmi As A Risk Factor For Early Dislocation Of Total Shoulder Arthroplasty, David J. Kusin, Joshua A. Ungar, Kaeli K. Samson, Matthew J. Teusink

Graduate Medical Education Research Journal

No abstract provided.

Do Pre-Operative Emotional And Mental Rand Sf-36 Scores Predict Outcomes After Total Hip And Knee Arthroplasty?, Erik Bowman, Curtis Hartman, Kevin Garvin, Beau Konigsberg, Liz Lyden, Seth Wardyn

Graduate Medical Education Research Journal

No abstract provided.

Three Cases Of Laryngeal Histoplasmosis In The Midwestern United States, Jonathan Blecha, Christopher Bingcang, Justin Oltman

Graduate Medical Education Research Journal

No abstract provided.

Left Ventricular Assist Device (Lvad) Infections: A Single Center Experience, Rajendra Karnatak, Uriel Sadkovsky

Graduate Medical Education Research Journal

No abstract provided.

Evaluation Of A Midline Catheter Program And Effect On Central Line Associated Blood Stream Infections, Richard Hankins, Mark Rupp, Teresa Micheels, Luana Evans, Angela Boesch, Kim Hayes, Adrienne Sy, Kelly Cawcutt

Graduate Medical Education Research Journal

No abstract provided.

Pseudo-Pseudotumor: A Cautionary Tale, Brian T. Westerhuis, Sachin Kedar

Graduate Medical Education Research Journal

No abstract provided.

Extraction Kinetics Of Free Thyroxine With Therapeutic Plasma Exchange In The Treatment Of Thyroid Storm In A Case Of Antithyroid Induced Pancytopenia, Ameena Madan Paramasivan, Abbey L. Fingeret, Sara M. Shunkwiler, Whitney S. Goldner

Graduate Medical Education Research Journal

No abstract provided.

Adherence To Practice Guidelines For Treating Diabetic Foot Infections: An Opportunity For Syndromic Stewardship, Randy Mccreery, Scott Bergman, Trevor Vanschooneveld

Graduate Medical Education Research Journal

No abstract provided.

Burnout In Pediatric Residents: When Is Burnout Most Likely To Occur During An Inpatient Service Month And What Are Its Associated Factors?, Maria Skorey, Valerine Rinehart, Kortany Mccauley, Katie Greenwood, Hao Hsu

Graduate Medical Education Research Journal

No abstract provided.

The Use Of Probiotics To Prevent Ventilator-Associated Pneumonia In Adults, Michael Roper, Paige Douthett

Physician Assistant Capstones, 2016 to 2019

Objective: To assess the efficacy and safety of preventing the acquisition of ventilator- associated pneumonia with the use of probiotic supplementation, as compared to a placebo, among hospitalized adult men and women receiving more than 24 hours of mechanical ventilation. Design: Systematic Literature Review. Methods: Systematic searches were conducted through PubMed and Scopus using the search terms “ventilator”, “probiotics”, and “prevention”. Records were excluded from the analysis if they were published before 2015, full text was not available, studies other than randomized control trial or cohort studies, and if the study population was less than 18 years old. Results: Of …

Vaxinsight: An Artificial Intelligence System To Access Large-Scale Public Perceptions Of Vaccination From Social Media, Jingcheng Du

Dissertations and Theses (Open Access)

Vaccination is considered one of the greatest public health achievements of the 20th century. A high vaccination rate is required to reduce the prevalence and incidence of vaccine-preventable diseases. However, in the last two decades, there has been a significant and increasing number of people who refuse or delay getting vaccinated and who prohibit their children from receiving vaccinations. Importantly, under-vaccination is associated with infectious disease outbreaks. A good understanding of public perceptions regarding vaccinations is important if we are to develop effective vaccination promotion strategies. Traditional methods of research, such as surveys, suffer limitations that impede our understanding of …

Improving The Rate Of Hand Hygiene Immediately Before And After Wound Care In The Street Nurse Microsystem, Amanda Ramos Sandoval

Master's Projects and Capstones

The street nurse team of Sacramento, CA provides many services to patients who are experiencing homelessness, including a substantial amount of wound care. While the street nurses were performing hand hygiene (HH) prior to and after wound care, they would often not be performing it immediately prior and post-wound care. Because the nurses hike to their patients (who are living on the streets or in out of the way camps) the street nurses would often perform hand hygiene while at their cars prior to going to the patient and again when they returned to their cars after performing wound care. …

An Approach To Increase Education In The Flu Vaccination Clinic Process, Koki Guangxi Inlow, Lucy Dale, Devante Lindsey, Nancy Tran Manalo, Elena Teresa Cleary

Master's Projects and Capstones

The Health Ministries Program, located in Orange County, is supported by a large faith-based community hospital and provides community resources such as flu vaccinations that are overseen by the Faith Community Nurse (FCN). In collaboration with the program, University of San Francisco (USF) nursing students researched and developed an implementation of a multi-purpose educational flyer to increase education and better streamline the process at flu vaccination clinics throughout Orange County faith-based organizations. Research shows that many individuals still do not get vaccinated due to misconceptions, misinformation, and lack of knowledge on the importance of flu vaccinations. The cost of flu-related …

Improving Identification Of Ssi In Snf, Jennifer Teng Yuan Yu

Master's Projects and Capstones

Educational deficit in basic wound assessment can lead to failure to recognize early signs of infection or wound deterioration. Despite many challenges towards wound care, there are potential opportunities to reduce patient injury and clinical outcomes through continuing education. The purpose of this paper is to review literature on current wound care knowledge in nurses and assess existing wound care knowledge in nurses at a skilled nursing facility. A 10-question pre-test wound assessment quiz based on the Bates-Jensen Wound Assessment Tool (BWAT) selected by the Wound Care Coordinator (WCC)/Wound Care Specialist (WCS) was given to 22 nurses: 5 Registered Nurses …

Use Of A Prevention Bundle To Reduce Colon Surgical Site Infections, Stephanie Kimberly Leong

Master's Projects and Capstones

Site Infections (SSIs) are the second highest amongst healthcare-associated infections (HAIs). SSI rates are disproportionally higher among colon surgeries, resulting in significant complications with adverse clinical and economic impacts (Keenan et al., 2014). The overall upward trend in SSI rates, including the increase colon SSI rates in 2018 called for immediate action in a 120-bed community medical center. A multidisciplinary team was assembled to implement an improvement initiative using evidence-based guidelines. An evidence-based care bundle was designed and implemented to prevent and reduce colon SSI rates. There are seven process measures: the use of chlorhexidine wipes preoperatively, hair clipping outside …

Zoonotic Risk Of Emerging Influenza Viruses From Domestic Animals, Sherry Blackmon

Theses and Dissertations

Influenza poses a significant global health risk due to the high morbidity and mortality associated with endemic strains and the pandemic potential of novel strains. This research characterizes the zoonotic risk of emerging influenza viruses from domestic animals. Chapter two investigates the genetic compatibility of pandemic H1N1 and emerging canine influenza H3N2 (CIV-H3N2), first identified in dogs in 2007 and currently responsible for outbreaks in shelters in the U.S. We generated 51 of the 127 possible reassortant viruses: 19 showed high-growth phenotypes and 13 replicated in mice lungs. A reassortant with the HA and NP genes derived from CIV-H3N2 transmitted …

Development And Evaluation Of An Automated System To Deliver A Live-Attenuated Edwardsiella Ictaluri Vaccine In Commercial Catfish Production Systems, John Wesley Lowe

Theses and Dissertations

Catfish aquaculture is the largest cultured food fish industry in the United States, accounting for approximately $375 million in sales annually, with Mississippi leading the industry with 36,200 surface acres of production. However, infectious diseases such as enteric septicemia of catfish (ESC) are decreasing production efficiencies, creating losses of $40-60 million annually. Live-attenuated oral ESC vaccines are effective in preventing ESC infections, but have not been widely adopted by the catfish industry due to the lack of a system to administer the oral vaccine at the scale seen in commercial catfish production systems. An automated system was developed to administer …

Effects Of The In Ovo Injection Of Vitamin D3 Sources On The Hatchability, Performance, Breast Meat Yield, Small Intestine Morphology, And Immunity Of Ross 708 Broilers Subjected To Dietary Insufficiency And Pathogenic Agents, Seyed Abolghasem Fatemi

Theses and Dissertations

Effects of varying dosages (0.6 to 4.8 μg/egg) of vitamin D3 (D3) and 25-hydroxycholecalciferol (25OHD3), administrated by in ovo (amniotic) injection, on various embryonic and post-hatch physiological variables in Ross 708 broilers were investigated. The in ovo injection of 1.2 to 4.8 μg of both D3 and 25OHD3 increased serum 25OHD3 concentrations in broiler embryos in comparison to non-injected and diluent-injected control groups. Furthermore, the effects of 2.4 μg of D3 and 25OHD3 alone and in combination on the performance, meat yield and quality, small intestine morphology, and immunity of the broilers fed a diet restricted in calcium and phosphorous …

Evaluation Of Health, Production Parameters, Time To First Detected Estrus, And Behavior In Dairy Cows Treated With Pegbovigrastim, Mauricio Xavier Da Silva Oliveira

Theses and Dissertations

Pegbovigrastim injection (IMR) represents a new approach in overcoming mastitis. The objective of this study was to evaluate production parameters, overall health, time to first detected heat, and behavior of cows treated with IMR or a saline control. Study cows (n = 270) were blocked by parity group (multiparous or primiparous) and randomly assigned to control (CON, n = 144) or treatment (IMR, n = 126). Milk yield, fat, protein, lactose, solids nonfat percent, somatic cell count, and body condition, hygiene, and lameness were evaluated weekly. Animals were evaluated for metritis twice weekly via evaluation of rectal temperature, per rectum …

Screening The Cultivable Cave Microbial Mats For The Production Of Antimicrobial Compounds And Antibiotic Resistance, Jerneja Ambrožič Avguštin, Patricia Petrič, Lejla Pašić

International Journal of Speleology

The current work extends the phenotypic characterization of a bacterial culture collection obtained from white, yellow, grey or pink microbial cave wall colonies that are common in the caves of Slovenian Karst. We have determined antibiotic resistance to 22 natural and synthetic antibiotics in 69 isolates from the microbial mats. Thirty-eight isolates (52%) were resistant to 1-5 antibiotics; another 27 isolates (37%) were resistant to 6-10 antibiotics; and 7 isolates (0.1%) were resistant to 11-17 antibiotics. We screened for production of antimicrobial compounds by growing cave isolates on five different media and overlaying individual cultures with ten Gram-positive and Gram …

Informing An Intervention To Address High-Risk Sexual Behavior In Hispanic Men Who Have Sex With Men, Jacob Martinez

Open Access Dissertations

Hispanic men who have sex with men (MSM) continue to be disproportionately affected by HIV infection. However, few interventions have been shown to be effective in decreasing high-risk sexual behaviors among Hispanic MSM. The purpose of this dissertation study was to explore factors that may contribute to Hispanic MSM engagement in interventions to decrease high-risk sexual behaviors and to add relevant data to inform a culturally appropriate intervention. A qualitative descriptive research design was utilized to conduct in-depth, semi-structured interviews with a sample of 21 Hispanic MSM from various collaborator community sites in Miami-Dade County, Florida. Data were analyzed using …

Impact Of Prevnar (Pcv13) Vaccine Recommendations In Pediatric And Immunocompetent Adults 65 Years And Older: What Are The Benefits And Risks?, James E. Watkins, Anne Marie Thibodeaux, John C. Darnell

Articles, Abstracts, and Reports

Background:

2000: PCV7 becomes the first FDA approved pneumococcal vaccine for pediatrics
2010: PCV13 recommended in pediatrics
2014: PCV13 recommended in immunocompetent adults 65+
2018: CDC looked at data since 2014 recommendation
2019: PCV13 now shared clinical decision-making

Synthesis And Preclinical Validation Of Novel P2y1 Receptor Ligands As A Potent Anti-Prostate Cancer Agent., Hien Thi Thu Le, Tatu Rimpilainen, Saravanan Konda Mani, Akshaya Murugesan, Olli Yli-Harja, Nuno R Candeias, Meenakshisundaram Kandhavelu

Articles, Abstracts, and Reports

Purinergic receptor is a potential drug target for neuropathic pain, Alzheimer disease, and prostate cancer. Focusing on the structure-based ligand discovery, docking analysis on the crystal structure of P2Y

The Method Summary Of Generating Large-Scale Artificial Population In An Artificial Society, Yuanzheng Ge, Zhichao Song, Rongqing Meng

Journal of System Simulation

Abstract: The generation of large-scale artificial population is the fundamental data of high-resolution agent-based artificial society. By the comparison of typical artificial population models, the basic elements, generating methods, and evolving rules, the development of artificial society, generation of population database, the establishment of spatial-temporal relationship, evolving rules of behavior, and reconstruction of social relationship are analyzed. Furthermore, data-driven method and open interface framework of artificial population are discussed, and the future direction and development are listed.

Distinct Roles Of Interferon Alpha And Beta In Controlling Chikungunya Virus Replication And Modulating Neutrophil-Mediated Inflammation, Lindsey E Cook, Marissa C Locke, Alissa R Young, Kristen Monte, Matthew L Hedberg, Raeann M Shimak, Kathleen C F Sheehan, Deborah J Veis, Michael S Diamond, Deborah J Lenschow

Open Access Publications

Type I interferons (IFNs) are key mediators of the innate immune response. Although members of this family of cytokines signal through a single shared receptor, biochemical and functional variation exists in response to different IFN subtypes. While previous work has demonstrated that type I IFNs are essential to control infection by chikungunya virus (CHIKV), a globally emerging alphavirus, the contributions of individual IFN subtypes remain undefined. To address this question, we evaluated CHIKV pathogenesis in mice lacking IFN-β (IFN-β knockout [IFN-β-KO] mice or mice treated with an IFN-β-blocking antibody) or IFN-α (IFN regulatory factor 7 knockout [IRF7-KO] mice or mice …

Chemical Constituent And Antimalarial Activity Based On Inhibition Of Heme Polymerization From Water Extract Of Yellow Root (Arcangelisia Flava L. Merr), Yatri Hapsari, Partomuan Simanjuntak, Wien Kusharyoto, Sumi Hudiyono

Chimica et Natura Acta

In developing countries, malaria remains a disease that can spread easily and caused death. Malaria is an infectious disease caused by Plasmodium sp involving female anopheles masquitos during its transmission. Arcangelisia flava L. Merr has been investigated earlier that it can inhibited P. falciparum growth. Method of antimalarial activity based on inhibition of heme polymerization can confirm one of the mechanism of antimalarial drugs. The aim of this research to study further antimalarial activity and IC50 based on inhibition of heme polymerization and determine the chemical constituent from water extract of A. flava L. Merr. This research was conducted through …

Pola Perubahan Urutan Asam Amino Pada Hemaglutinin Virus H5n1 Indonesia, Idar Idar, Soni Muhsinin, Umi Baroroh, Muhammad Yusuf

Chimica et Natura Acta

Wabah virus flu burung tipe A, H5N1 yang memiliki patogenisitas tinggi diketahui telah menginfeksi dan mematikan jutaan unggas di Indonesia sehingga menimbulkan kerugian yang besar secara ekonomi pada peternakan unggas.  Hemaglutinin pada virus ini merupakan salah satu faktor penentu patogenisitas virus. Selain itu, komponen virus ini rentan mengalami mutasi dan dapat menyebabkan pergeseran dan penataan ulang antigen virus sehingga tercipta clade virus yang baru. Kemudian peranan HA dalam penempelan virus ke sel inang menyebabkan HA ini menjadi target untuk pengembangan obat maupun vaksin. Dengan demikian, penelitian ini bertujuan mencari pola urutan asam amino hemaglutinin yang khas pada H5N1 yang memiliki …

The Resistance To Flouridation, Carl M. Williams

Wyoming Law Journal

No abstract provided.

Volume 57, Number 18: December 11, 2019, University Of North Dakota

University Letter Archive

No abstract provided.

Does Dispensing Naloxone Kits To High-Risk Patients At The Time Of Emergency Department (Ed) Discharge Reduce The Burden Of Subsequent Overdose-Related Care?, Steven D. Perry, Charleen Gnisci, Rachel Beham

Emergency Medicine

Purpose: The rates of opioid-related overdose and death have remained at or near historically high levels despite reform in pharmaceutical opioid prescribing trends. This study will determine if a recently implemented protocol which aims to provide high-risk patients with naloxone emergency kits at the time of ED discharge has reduced the need for subsequent overdose-related care to a greater degree than providing the same patients with written outpatient naloxone prescriptions. Patients currently receive either intervention upon discharge from the ED based on a protocolized, criteria-based, provider-implemented decision-making tree that identifies patients at high risk for subsequent overdose.

Methods: This study …