Digital Commons Network^™

Evaluation Of Antibacterial And Antioxidant Potential Of Some Homoeopathic Mother Tinctures, Tayyeba Rehman, Ahmad Saeed

Indian Journal of Research in Homoeopathy

Objectives: In homoeopathic system of medicine, mother tinctures are prescribed for several diseases especially for septic conditions and cure of many illnesses. This study was done to evaluate the antibacterial and antioxidant potential of ten commonly used homoeopathic mother tinctures. Materials and Methods: Ten prepared mother tinctures were tested against five clinically important human pathogenic bacteria (Salmonella typhi [S.T], Escherichia coli [E.C], Bacillus subtilis [B.S], Staphylococcus aureus [S.A], and Pseudomonas aeruginosa [P.A]) by broth micro-dilution method with ciprofloxacin as positive control. Antioxidant activity was estimated by 2,2-diphenyl 1-picryl hydrazyl (DPPH) inhibition assay. Ascorbic acid was taken as positive standard in …

Anura Distribution And Richness In A Tropical Montane Forest In Monteverde, Costa Rica, June 2019, Elizabeth L. Mcdonald

Monteverde Institute: Tropical Ecology and Conservation

Tropical regions, especially tropical montane regions, are biodiversity hotspots for amphibians. In tropical montane forests, varying temperatures and precipitation along an elevational gradient create distinct Holdridge life-zones for the 51 species of frogs and toads in Monteverde, Costa Rica. However, changing climatic conditions, and other complex factors, have contributed to recent anuran declines in the Monteverde area and worldwide. Shifting abiotic conditions cause species to move to new areas with suitable conditions. Within this study, I establish a data set complimentary to previous baselines of anuran distributions in local areas. In doing so, current encountered distributions can be compared to …

To What Extent The World Health Organization's Policies Of Antimicrobial Resistance Are Implemented In Egyptian Hospitals., Amira Farouk Hussein

Theses and Dissertations

Antimicrobial resistance is a major public health problem. In the Egyptian hospitals, the problem was discovered since 2006; however, seven years ago, this problem drew the attention to be one of the major risk factors worldwide and in the Egyptian hospitals as well. International organizations, such as the World Health Organization (WHO) tried to find different solutions to prevent transmission of these communicable diseases from country to another by setting different guidelines and standards to be followed by countries. The case is to assess the barriers to implementation of objectives and guidelines of WHO in one of the biggest public …

Current In Vivo Models Of Varicella-Zoster Virus Neurotropism, Ravi Mahalingam, Anne Gershon, Michael Gershon, Jeffrey I. Cohen, Ann Arvin, Leigh Zerboni, Hua Zhu, Wayne Gray, Ilhem Messaoudi, Vicki Traina-Dorge

Faculty and Student Publications

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Varicella-zoster virus (VZV), an exclusively human herpesvirus, causes chickenpox and establishes a latent infection in ganglia, reactivating decades later to produce zoster and associated neurological complications. An understanding of VZV neurotropism in humans has long been hampered by the lack of an adequate animal model. For example, experimental inoculation of VZV in small animals including guinea pigs and cotton rats results in the infection of ganglia but not a rash. The severe combined immune deficient human (SCID-hu) model allows the study of VZV neurotropism for human neural sub-populations. Simian varicella virus …

Drug-Induced Acute-On-Chronic Liver Failure In Asian Patients, Harshad Devarbhavi, Saeed Hamid

Section of Gastroenterology

Objectives: Acute insults from viruses, infections, or alcohol are established causes of decompensation leading to acute-on-chronic liver failure (ACLF). Information regarding drugs as triggers of ACLF is lacking. We examined data regarding drugs producing ACLF and analyzed clinical features, laboratory characteristics, outcome, and predictors of mortality in patients with drug-induced ACLF.

Metods: We identified drugs as precipitants of ACLF among prospective cohort of patients with ACLF from the Asian Pacific Association of Study of Liver (APASL) ACLF Research Consortium (AARC) database. Drugs were considered precipitants after exclusion of known causes together with a temporal association between exposure and decompensation. Outcome …

Forests And Health In Mexico: Preliminary And Pre-Preliminary Work - June 2019, Alejandro López-Feldman

Forest Collaborative Research

Presentation focuses on subjective wellbeing and natural protected areas in Mexico

Conference Introduction: Setting The Stage - June 2019, Allen Blackman

Forest Collaborative Research

Conference welcome, goals, agenda, and brief self-introductions.

Is It Really Transverse Myelitis? Acute Flaccid Myelitis A Rare Entity., Hina Yusuf, Arsalan Ahmad, Ejaz Ahmed Khan

Pakistan Journal of Neurological Sciences (PJNS)

Acute Flaccid Myelitis is a relatively new and rare disease entity which was recognized for the first time in United States in 20121. Usually children below 18 years of age present with sudden onset rapidly progressive flaccid paralysis sometimes following upper respiratory tract infection. To date no cases have been reported from Afghanistan and Pakistan. We are reporting case of a young girl who presented with sudden onset flaccid paralysis and respiratory distress. Her MRI Cervical spine showed longitudinally extensive transverse myelitis. One year after the onset of disease flaccid paraparesis continued despite various treatments. It is important to report …

Bicyclic Peptides: Types, Synthesis And Applications, Shahrzad Ahangarzadeh, Mohammad M. Kanafi, Simzar Hosseinzadeh, Ahad Mokhtarzadeh, Mahmood Barati, Javad Ranjbari, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Bicyclic peptides form one of the most promising platforms for drug development owing to their biocompatibility, similarity and chemical diversity to proteins, and they are considered as a possible practical tool in various therapeutic and diagnostic applications. Bicyclic peptides are known to have the capability of being employed as an effective alternative to complex molecules, such as antibodies, or small molecules. This review provides a summary of the recent progress on the types, synthesis and applications of bicyclic peptides. More specifically, natural and synthetic bicyclic peptides are introduced with their different production methods and relevant applications, including drug targeting, imaging …

Eradication Of Human Immunodeficiency Virus Type-1 (Hiv-1)-Infected Cells, Nejat Düzgüneş, Krystyna Konopka

All Dugoni School of Dentistry Faculty Articles

Predictions made soon after the introduction of human immunodeficiency virus type-1 (HIV-1) protease inhibitors about potentially eradicating the cellular reservoirs of HIV-1 in infected individuals were too optimistic. The ability of the HIV-1 genome to remain in the chromosomes of resting CD4+ T cells and macrophages without being expressed (HIV-1 latency) has prompted studies to activate the cells in the hopes that the immune system can recognize and clear these cells. The absence of natural clearance of latently infected cells has led to the recognition that additional interventions are necessary. Here, we review the potential of utilizing suicide gene therapy …

Attenuation Of Complete Freund's Adjuvant-Induced Arthritis By Different Dilutions Of Eupatorium Perfoliatum And Crotalus Horridus And Their Safety Evaluation, Surender Singh, Karwasra Ritu, Prerna Kalra, Debadatta Nayak, Anil Khurana, Raj Manchanda

Indian Journal of Research in Homoeopathy

Objective: The aim of this study was to investigate, the inhibitory effect of the homoeopathic drugs – Eupatorium perfoliatum and Crotalus horridus in experimental models of inflammation and Complete Freund's Adjuvant (CFA)-induced arthritis with evaluation of their safety aspects by acute and subacute toxicity studies. Materials and Methods: Animals were divided into eight groups (n = 6). Eupatorium perfoliatum and Crotalus horridus in different dilutions (6CH, 12CH, 30CH and 200CH) were administered orally, daily during the study period of 21 days, and their effect on joint dysfunction was evaluated by measuring joint diameter in CFA-induced arthritis model. In addition, inflammatory …

Perception And Utilization Of Complementary And Alternative Medicine (Cam) Among University Of Sharjah (Uos) Students, Osama Mohamed Ibrahim, Mohamed E. A. Rashrash, Sameh Soliman

Bulletin of Faculty of Pharmacy Cairo University

Background: Complementary and Alternative Medicine (CAM) is a term used for practices and use of products other than conventional standard evidence-based medical care. Objective: To assess the CAM knowledge and utilization among University of Sharjah students, UAE. Method: A cross-sectional survey study was conducted. 250 surveys among UOS students were distributed. The data was obtained through a well-designed questionnaire of 3 main categories. The first part was designed to collect socio-demographic data, while the second part mainly measured CAM knowledge and the practicing pattern. The last section was developed to assess CAM beliefs and psychological behavior behind CAM utilization. Results: …

Awareness Of Human Papillomavirus Infection Complications, Cervical Cancer, And Vaccine Among The Saudi Population: A Cross-Sectional Survey, Mazen M. Almehmadi, Magdi M. Salih, Ayman S. Al-Hazmi

Saudi Medical Journal

Objectives: To determine human papillomavirus (HPV) infection, cervical cancer, and vaccine awareness among the Saudi population. Methods: This cross-sectional study of a convenience sample comprising 1033 participants (males and females) from different parts of Kingdom of Saudi Arabia was conducted between August 2018 and January 2019 using a web-based questionnaire. This self-administrated questionnaire was distributed to all participants. Collected data included age groups, cervical cancer, Papanicolaou (Pap) smear, and HPV vaccine awareness. Results: The response rate was 95%. Approximately 50% of the participants were 15-22 years old, <3% were >46 years old, and <10% had heard of HPV. Awareness and previous knowledge of the Pap smear as a screening tool was variable with male (5.9%) and female (27.9%) participants, having knowledge of the test. There were no statistically significant differences ( p >0.05) between males and females in their knowledge of …

June 2019 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

State Requirements For Mandatory Vaccine Education Prior To Exemption, Chelsea Lynn Schult

Theses and Dissertations

Background: To prevent the spread of Vaccine Preventable Diseases (VPD’s), school-aged children in the United States are required to receive vaccinations. In certain states, parents have the option to exempt their child from becoming vaccinated due to medical, religious, or personal reasons. The purpose of this research was to identify which states require mandatory vaccination education prior to granting vaccine exemptions and to identify the various types of required vaccination education.Methods: Immunization program managers from states requiring parents seeking exemptions to receive mandatory vaccination education were asked a series of open-ended questions. The interviews were conducted via telephone. The education-related …

Identification Of Novel Cyp2e1 Inhibitor To Investigate Cellular And Exosomal Cyp2e1-Mediated Toxicity, Mohammad Arifur Rahman

Theses and Dissertations (ETD)

Cytochrome P450 2E1 (CYP2E1)-mediated hepatic and extra-hepatic toxicity is of significant clinical importance. Diallyl sulfide (DAS) has been shown to prevent xenobiotics such as alcohol- (ALC/ETH), acetaminophen- (APAP) induced toxicity and disease (e.g. HIV-1) pathogenesis. DAS imparts its beneficial effect by inhibiting CYP2E1-mediated metabolism of xenobiotics, especially at high concentration. However, DAS also causes toxicity at relatively high dosages and with long exposure times. The objective of the first project was to find potent DAS analogs which can replace DAS as a research tool or as potential adjuvant therapy in CYP2E1-mediated pathologies.

Arachidin 3 Modulation Of Lipid Metabolism In Rotavirus Infections, Stormey Wisdom

Electronic Theses and Dissertations

Rotavirus (RV) can cause severe and deadly gastroenteritis in young children, infants, and immunocompromised individuals. Previous studies have shown that arachidin 3 (A3) inhibits RV replication, and that RV replication is dependent on the presence of lipids. This study investigated the alteration of lipid metabolism by A3 in RV infected HT29.f8 cells. A decrease in the RV regulation of lipid biosynthesis genes was observed with the addition of A3 using qRT-PCR. Also, immunofluorescent and histochemical staining for neutral fats, a major component of cellular lipid droplets, revealed an increased accumulation with both RV and RV+A3 when compared to no virus …

Coercive Control In Long Term Sex Trafficking Relationships: Using Exhaustion To Control Victims, Nicole C. Bassil

Student Theses

The importance of coercive control tactics in maintaining women in commercial sex has been well-documented. Less known is how these tactics manifest in long-term relationships and how victims cope or react to establish patterns of control. The current study measured the temporal patterning of coercive control in long term sex trafficking relationships via wiretapped phone conversations between pimps and sex trafficked workers. In addition, victim responses of compliance versus resistance to coercive control tactics were measured. 68 phone calls over four months were transcribed and coded between two pimps and four women working in commercial sex. The findings indicate that …

We Shall Overcome: The Association Between Family Of Origin Adversity, Coming To Terms, And Relationship Quality For African Americans, Kylee Marshall

Theses and Dissertations

Because adverse childhood and family of origin experiences may have implications for adult relationships, it is important to understand what can help buffer potential negative effects. The current study was designed to understand the relationship between childhood family of origin adversities, coming to terms with family of origin issues and events, and adult romantic relationship quality for African Americans (N = 1613). A path analysis was conducted using data from the RELATE assessment (see www.relate-institute.org). Results indicated that, taken together, coming to terms, self-esteem, and depression likely partially mediated the relationship between family of origin adversity and adult relationship quality. …

The Transformative Possibilities Of The Microbiota And Mycobiota For Health, Disease, Aging, And Technological Innovation, Lucas Jones, Jessica Kumar, Adil Mistry, Thriveen Sankar Chittoor Mana, George Perry, Prakash Reddy, Mark Obrenovich

Chemistry Faculty Research & Creative Works

The gut microbiota is extremely important for the health of the host across its lifespan. Recent studies have elucidated connections between the gut microbiota and neurological disease and disorders such as depression, anxiety, Alzheimer's disease (AD), autism, and a host of other brain illnesses. Dysbiosis of the normal gut flora can have negative consequences for humans, especially throughout key periods during our lifespan as the gut microbes change with age in both phenotype and number of bacterial species. Neurologic diseases, mental disorders, and euthymic states are influenced by alterations in the metabolites produced by gut microbial milieu. We introduce a …

Intraparotid Tuberculosis Misdiagnosed As Neoplasm On Fnac, Tahir Muhammad, Haissan Iftikhar, Mubasher Ikram

Department of Surgery Docs

No abstract provided.

Risk Factors Associated With Surgical Site Infections: A Retrospective Report From A Developing Country, Shahbaz Ansari, Sundus Fareed, Habiba D. Barry, Tariq Ali Bhatti, Syed Zohaib Maroof Hussain, Shah Jabeen, Sundus Fareed

Department of Surgery Docs

Introduction Any infection occurring at the site of a surgical incision superficially or deep within the fascia, within 30 days of a surgical procedure is termed as a surgical site infection (SSI). Due to limited resources, non-adherence to infection control guidelines and substandard sterilization practices, the incidence is higher in developing countries. The aim of this study is to estimate the incidence of surgical site infections in general surgeries at a tertiary care hospital in Pakistan and identify the predisposing risk factors. Methods This was a retrospective analysis that included all surgical records from June 1, 2018, to December 31, …

Exploring The Relationship Between Medical Insurance And Vaccine Acceptance Rates, Mark Knouse Md, Yennifer Lopez, Hope Kincaid Mph, Cph, Shae Duka Bs

Department of Medicine

No abstract provided.

Experience Of An Infectious Diseases (Id) Travel Medicine Clinic During A National Shortage Of Yellow Fever Vaccine (Yfv), Mark Knouse Md, Terri I. Langham Rn, Marcelo Gareca Md, Jarrod W. Kile Rphd

Department of Medicine

No abstract provided.

The Lancet Commission On Global Health Law: The Transformative Power Of Law To Advance The Right To Health, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

A new report by The Lancet-O’Neill-Georgetown University Commission on Global Health and the Law shows how law can fulfill the global pledge of the human right to health, while “leaving no one behind.” I call this “global health with justice.” We need both health and justice. By global health, I mean ever increasing indicators of good health and increased longevity in all countries around the world. By justice I mean that the global “good” of health must be fairly distributed both within and among countries. The Lancet Commission report offers a comprehensive roadmap towards realizing the law’s power to make …

The Histopathological Pattern Of Benign And Non-Neoplastic Skin Diseases At King Fahad Hospital, Madinah, Saudi Arabia, Abdulkader M. Albasri, Irfan A. Ansari

Saudi Medical Journal

Objectives: To characterize and compare the histopathological pattern of benign skin diseases in patients from Madinah region of Saudi Arabia. Methods: This retrospective study was conducted at the Department of Pathology, King Fahad Hospital, Madinah, Saudi Arabia, and contained cases of benign skin diseases for 11 years (from January 2006 to December 2017). The findings were tabulated in Microsoft Excel sheet and classified based on histopathological diagnosis. Results: Of 1,125 skin tissues reviewed, 579 (51.5%) specimens were from male patients and 546 (48.5%) specimens were from females giving a male: female ratio of 1.1:1. The ages ranged from 1 to …

Do Stands Of Native Trees Harbor Different Invasive Species Than Stands Of Planted Pine?, Carly Mccameron, John Mccarthy, Dr. Kevin Geedey

Celebration of Learning

The most outstanding invasive species that can be found at Augustana’s Green Wing Environmental Laboratory are honeysuckle, buckthorn, multiflora rose, garlic mustard, autumn olive, and oriental bittersweet. These plants are not only disrupting the ecosystem at Green Wing, but they are doing it all over the country. The result of their disruption is that they have taken over entire habitats and left natural species with no way to compete for survival. To study this we used the line-point method as well as other forms of data collection to compare a non-native pine tree habitat to an area dominated by native …

2019 Graduate Medical Education Research Day Compendium, Unlv School Of Medicine

Graduate Medical Education Research Day Compendium

Anyone engaged in research knows that the process can be daunting. Add the rigors of training in a graduate medical education program to this, and it might seem all but impossible to accomplish anything meaningful. However, the individuals highlighted in our 2019 Graduate Medical Education Research Day Compendium were able to overcome those odds. Their abstracts are showcased here and their efforts to advance the collective knowledge in their respective fields are commendable. We thank these Resident and Fellow Physicians and all who have supported them in their endeavors to reach this point with their research. Most of all, we …

A Behavioral And Physiological Investigation Of The Effects Of Nicotine On Human Reward Responding And Fear Conditioning, Alexandra N. Palmisano

Doctoral Dissertations

Although considerable progress has been made, we do not fully understand the neuropsychological properties of nicotine that drive nicotine dependence. The present body of work provides an original investigation of the effects of nicotine on behavioral and physiological responding for rewarding and aversive stimuli in humans, which arises from considerable nonhuman investigations of nicotine’s complex interactions in conditioned learning. In order to accomplish this goal, three distinct studies were conducted. Given evidence that nicotine enhances operant responding for nonpharmacological reinforcers, Study 1 assessed the ability of nicotine to enhance food reward sensitivity using a virtual reality conditioned place preference …

The Influence Of Behavioral Cues On Immunization Practices Of Elders, Lynn A. Chilton

Dissertations

A quasi-experimental intervention study was designed to compare the influence of behavioral cues on immunization practices of elders. Elders also were surveyed to determine immunization practices related to influenza and pneumonia and to ascertain reasons for under-immunization among this age group. The Neuman Systems Model and the Health Belief Model were used as conceptual frameworks to guide the study. Data were collected utilizing a Demographic Survey (DS) and an Immunization Survey (IS).