Digital Commons Network^™

Presentation Et Commentaires: L'Évanegélisation De La Côte D'Lvoire. Préhistoire D'Un Centenaire, Paul Coulon

Mémoire Spiritaine

No abstract provided.

La Monarchie De Juillet, L'Église De France Et L'Esclavage, Philippe Delisle

Mémoire Spiritaine

No abstract provided.

Judy Chicago’S Dinner Party: Contextualizing The Critical Reaction, Noreen Mcgonigle

Art Journal

No abstract provided.

Liberty And Justice For All?: Female Portraiture In The Age Of The Early American Republic, Mary Grace Day

Art Journal

No abstract provided.

Shifts In Mindset: An Exploration Of Art In The Paleolithic And Neolithic Periods, Vivienne Strmecki

Art Journal

No abstract provided.

Art Journal 2019 - Perspectives

Art Journal

No abstract provided.

B-Lymphocyte Phenotype Determines T-Lymphocyte Subset Differentiation In Autoimmune Diabetes., Leire Egia-Mendikute, Berta Arpa, Estela Rosell-Mases, Marta Corral-Pujol, Jorge Carrascal, Jorge Carrillo, Conchi Mora, Harry Chapman, Anaïs Panosa, Marta Vives-Pi, Thomas Stratmann, David V. Serreze, Joan Verdaguer

Faculty Research 2019

Previous studies indicate that B-lymphocytes play a key role activating diabetogenic T-lymphocytes during the development of autoimmune diabetes. Recently, two transgenic NOD mouse models were generated: the NOD-PerIg and the 116C-NOD mice. In NOD-PerIg mice, B-lymphocytes acquire an activated proliferative phenotype and support accelerated autoimmune diabetes development. In contrast, in 116C-NOD mice, B-lymphocytes display an anergic-like phenotype delaying autoimmune diabetes onset and decreasing disease incidence. The present study further evaluates the T- and B-lymphocyte phenotype in both models. In islet-infiltrating B-lymphocytes (IIBLs) from 116C-NOD mice, the expression of H2-K^d and H2-A^g7 is decreased, whereas that of …

The Traits That Predict The Magnitude And Spatial Scale Of Forest Bird Responses To Urbanization Intensity, Grant D. Paton, Alexandra V. Shoffner, Andrew M. Wilson, Sara A. Gagné

Environmental Studies Faculty Publications

As humans continue moving to urban areas, there is a growing need to understand the effects of urban intensification on native wildlife populations. Forest species in remnant habitat are particularly vulnerable to urban intensification, but the mechanisms behind these effects are poorly understood. An understanding of how species traits, as proxies for mechanisms, mediate the effects of urban intensification on forest species can help fill this knowledge gap. Using a large point count dataset from the Second Pennsylvania Breeding Bird Atlas, we tested for the effects of species traits on the magnitude and spatial scale of the responses of 58 …

Observing The Oceans Acoustically, Bruce M. Howe, Jennifer L. Miksis-Olds, Eric Rehm, Hanne Sagen, Peter F. Worcester, Georgios Haralabus

Center for Coastal and Ocean Mapping

Acoustics play a central role in humankind’s interactions with the ocean and the life within. Passive listening to ocean “soundscapes” informs us about the physical and bio-acoustic environment from earthquakes to communication between fish. Active acoustic probing of the environment informs us about ocean topography, currents and temperature, and abundance and type of marine life vital to fisheries and biodiversity related interests. The two together in a multi-purpose network can lead to discovery and improve understanding of ocean ecosystem health and biodiversity, climate variability and change, and marine hazards and maritime safety. Passive acoustic monitoring (PAM) of sound generated and …

Biocompatible Polymeric Nanoparticles With Innovative Structural Design For Oral Delivery Of Lipophilic Bioactives, Qiaobin Hu

Doctoral Dissertations

Archival abstract submitted

Dating, Dining, And Ducks: Monitoring The Recovery Of Campus Lakes After Dredging, Emily A. Kane, Christian Cox

Sustainability Showcase (2014-2022)

Dr. Emily Kane, Assistant Professor, Department of Biology ($30,000.00)

Monitored pond recovery after recent dredging by involving students to survey these ponds each month for 1 year. Results were shared in hopes of promoting an understanding of campus biodiversity, the ecology of these ponds, and the importance of sustainable activities.

Eelgrass Pathogen Labyrinthula Zosterae Synthesizes Essential Fatty Acids, R. M. Yoshioka, Julie B. Schram, Aaron W. Galloway

Faculty, Staff, and Students

Negative consequences of parasites and disease on hosts are usually better understood than their multifaceted ecosystem effects. The pathogen Labyrinthula zosterae (Lz) causes eelgrass wasting disease but has relatives that produce large quantities of nutritionally valuable long-chain polyunsaturated fatty acids (LCPUFA) such as docosahexaenoic acid (DHA). Here we quantify the fatty acids (FA) of Lz cultured on artificial media, eelgrass-based media, and eelgrass segments to investigate whether Lz may similarly produce LCPUFA. We also assess whether fieldcollected lesions show similar FA patterns to laboratory-inoculated eelgrass. We find that Lz produces DHA as its dominant FA along with other essential FA …

Targeting Pathogenic Lafora Bodies In Lafora Disease Using An Antibody-Enzyme Fusion, M. Kathryn Brewer, Annette M. Uittenbogaard, Grant L. Austin, Dyann M. Segvich, Anna Depaoli-Roach, Peter J. Roach, John J. Mccarthy, Zoe R. Simmons, Jason A. Brandon, Zhengqiu Zhou, Jill Zeller, Lyndsay E. A. Young, Ramon C. Sun, James R. Pauly, Nadine M. Aziz, Bradley L. Hodges, Tracy R. Mcknight, Dustin D. Armstrong, Matthew S. Gentry

Molecular and Cellular Biochemistry Faculty Publications

Lafora disease (LD) is a fatal childhood epilepsy caused by recessive mutations in either the EPM2A or EPM2B gene. A hallmark of LD is the intracellular accumulation of insoluble polysaccharide deposits known as Lafora bodies (LBs) in the brain and other tissues. In LD mouse models, genetic reduction of glycogen synthesis eliminates LB formation and rescues the neurological phenotype. Therefore, LBs have become a therapeutic target for ameliorating LD. Herein, we demonstrate that human pancreatic α-amylase degrades LBs. We fused this amylase to a cell-penetrating antibody fragment, and this antibody-enzyme fusion (VAL-0417) degrades LBs in vitro and dramatically reduces LB …

Ecology Of Upland Snake Communities In Managed Montane Longleaf Pine Habitats Of Georgia, Miranda Gulsby

Master of Science in Integrative Biology Theses

Longleaf pine ecosystem decline in the Southeast United States has led to intensive land management implementation with the goal to benefit both the ecosystem and at-risk species. Addressing at-risk snake populations in these longleaf pine ecosystems, for instance, requires understanding both community and species level ecology of snakes in these managed forests. Data for snakes in the montane (mountain) longleaf pine habitats remains unclear since management practice implementation. Currently, intensive restoration of montane longleaf pine habitats is taking place within two Wildlife Management Areas (WMA) in the Raccoon Creek Watershed of Northwest Georgia, Sheffield and Paulding Forest. These areas differ …

Short '09 Identifies New Species Of Rhinoceros, Samira Kassem

News and Events (Discontinued Series)

No abstract provided.

Ways Of Seeing: Historicization, Technologization And Chinese Artistic Experience, Tairan Liu

Theoretical Studies in Literature and Art

Marx raised the issue of "the historicization of senses", arguing that the fundamental feature to distinguish humans from animals is that humans can use their techniques to foresee certain types of things in the future which are not given by the nature but are created by humans. However, issues such as the relationships between technology and the body, between technology and labor, and between technology and the ways of human-sensing invite further investigation. Chinese artistic experience enables us to separate "historicization of senses" from "technologization of senses" under new historical conditions, and then we may reflect on the globalization and …

“Anyone Can Co-Design?”: A Case Study Synthesis Of Six Experience-Based Co-Design (Ebcd) Projects For Healthcare Systems Improvement In New South Wales, Australia, Tara L. Dimopoulos-Bick, Claire O'Connor, Jane Montgomery, Tracey Szanto, Marion Fisher, Violeta Sutherland, Helen Baines, Phillip Orcher, John Stubbs, Lynne Maher, Raj Verma, Victoria J. Palmer

Patient Experience Journal

Experience-based co-design (EBCD) is a quality improvement approach that is being used internationally to bring service users and health professionals together to improve healthcare experiences, systems and processes. Early evaluations and case studies of EBCD have shown promise in terms of improvements to experience and organisational processes, however challenges remain in participation around shared power and decision making, mobilisation for implementation, sustainment of improvements and measurement of outcomes. The objective of this case study was to explore the emergent issues in EBCD participation and implementation in six quality improvement projects conducted in mental health, rehabilitation, blood and bone marrow transplant, …