Digital Commons Network^™

Human Behavioral Response To The Younger Dryas In North Alabama: An Analysis Of The Richard L. Kilborn Collection, Robert A. Barlow

Theses and Dissertations

This study is a collections-based project that employs approximately 1,300 projectile points to investigate behavioral response to the Younger Dryas in north Alabama (12,900 to 11,700 BP). I apply a version of the marginal value theorem to determine how changing resource structures caused changes in projectile point technology. I argue that changes in technology during the Younger Dryas were not conditioned by access or availability of lithic raw material. Instead, variation in technology is likely a response to changes in return rates from hunting and foraging. Further, the changes in hunting return rates correlate with changes in north Alabama forest …

Illusionary Success: Modern Failures In Child Welfare, Courtney Harris

Theses and Dissertations

Child welfare is constantly labeled as “failure- riddled” and “scandalous” with high rates of children who are in an endless cycle of removal, reunification, and removal. Some children have lifelong abuse ramifications due to a longstanding history of childhood abuse. Other children, unfortunately, pay the ultimate price and die. State Child Welfare entities are working within their confines and become bound by federal and state statutes and laws. While media and citizen onlookers criticize and blame the state, workers, and families, the field suffers from a lack of better offers. This dissertation seeks to use the state of Tennessee as …

Macromolecular Prodrug For The Treatment Of Ulcerative Colitis, Yuanyuan Sun

Theses & Dissertations

Ulcerative colitis is a chronic inflammatory bowel disease affecting the colon. More than 1 million Americans are affected, with the annual economic burden up to 14.9 billion in the United States. By far, ulcerative colitis still lacks the cure and the current treatment strategies are limited due to severe side effects and in-sufficient efficacy. The tofacitinib (Xeljanz) is the only approved oral medication by for adults with moderately-to-severely-active ulcerative colitis. But the related side effects and serious infections still have to be resolved. In the previous study in our lab, the researchers have successfully developed and characterized multiple hy-drophilic prodrug …

Propolis Modulates Inflammatory Mediators And Improves Histopathology In Male Rats With L-Arginine-Induced Acute Pancreatitis, Mohammed T. Al-Hariri, Tharwat G. Eldin, Tarek Chathoth, Shahanas, Abdullah Alswied

Sultan Qaboos University Medical Journal

Objectives: This study aimed to determine the effects of propolis on immune mediators and tissue histopathology in rats with L-arginine-induced acute pancreatitis (AP). Methods: This study was conducted at Imam Abdulrahman Bin Faisal University, Dammam, Saudia Arabia between September and November 2017. A total of 24 male albino Wistar rats were divided into three equal groups. Group one was the negative control, group two was the positive control (L-arginine-induced AP) and group three received treatment (L-arginineinduced AP and propolis). The rats in group three were treated with 100 mg/kg propolis for seven days after AP induction. Pancreatic tissue was evaluated …

Living Beyond Words: Post-Human Reflections On Making Music With Post-Verbal People, Jocey Quinn, Claudia Blandon, Anna Batson

School of Law, Humanities and Social Sciences

Background: This paper draws on a longitudinal ethnographic study of music-making with “post-verbal” people: those with stroke, learning difficulties, acquired brain injury, dementias or autism. Methods: Using embedded observation, arts workshops, interviews with families and carers and focus groups with Music Leaders, the project traced how inclusive music-making happens with “post-verbal” people. It used post-human theory to illuminate and explore processes and benefits. Results: This paper fuses the practical and theoretical aspects of making music with post-verbal people, to understand both how it happens, and, what it signifies. It shows how post-verbal people use music to communicate and demonstrate their …

Low Secondary Risks For Captive Coyotes From A Sodium Nitrite Toxic Bait For Invasive Wild Pigs, Nathan P. Snow, Katherine E. Horak, Simon T. Humphrys, Linton D. Staples, David G. Hewitt, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

An acute toxic bait is being developed to deliver micro‐encapsulated sodium nitrite (SN) to stimulate severe methemoglobinemia and humane death for invasive wild pigs (Sus scrofa), thereby providing a new tool for reducing their populations. During April 2016, we evaluated sensitivity to SN and outcomes of secondary consumption in the ubiquitous mammalian scavenger, coyote (Canis latrans), to determine secondary risks of consuming carcasses of wild pigs that died from consuming the SN toxic bait. At the National Wildlife Research Center in Fort Collins, Colorado, USA, we first evaluated whether coyotes fed carcasses of domestic pigs killed by consumption of SN …

Relationship Between Empathy And Language Proficiency In Adult Language Learners, Mika Sakai

Dissertations and Theses

This study reviews concepts and the mechanism of empathy, and the relationship between empathy and language proficiency, focusing on the aspect of cognitive empathy. It also discusses whether empathy levels could be developed by learning language to a highly proficient level. I compared the empathy levels between high and low proficiency second-language learners to determine if there was correlation between empathy and other factors such as gender, studying abroad, education background, and usage of a second language. I found that there was no relationship between empathy level and language proficiency level; however, there was one between empathy and gender. For …

The Whistling Thief, Author Unknown

Broadside Ballads: England

A mother deters her daughter's suitors from pretending to be animals and the wind.

Understanding The Impact Of Fluid Viscosity On The Growth And Conjugation Of Antimicrobial Resistant Donors And Recipients Pairs, Judah Pemble, Alex Chabrelie, Jade Mitchell, Phd

Journal of Health Disparities Research and Practice

To combat the spread of antimicrobial resistance (AMR), it is vital to link the behavior of donor and recipient bacteria in dynamic environments to horizontal gene transfer (HGT) potential- specifically, conjugation the primary means of spread of AMR genes. However, HGT is poorly understood under dynamic conditions, such as those in the gut of humans and animals. Most experiments are done under static conditions at viscosities similar to water, but these methods do not accurately represent the higher gut viscosities or movement. Hence, a next step to increase understanding of conjugation is with experiments using generic donor and recipient pairs …

Effects Of A Histone Methyltransferase Inhibitor On Fertility On A Rat Model Of Endometriosis, Diego Garcia, Inevy Seguinot Tarafa, Idhaliz Flores, Phd

Journal of Health Disparities Research and Practice

Endometriosis is an estrogen-dependent, inflammatory disease that affects 5-10% of women of reproductive age. It is defined as the growth of functioning endometrium outside the uterus that results in severe pelvic pain and often infertility. Currently, endometriosis has no cure, and available treatments have limited efficacy and side effects. Epigenetics play a key role in the etiology of this disease, and we have previously shown that treatment with histone methyltransferase inhibitors (HMTi) in an animal model of endometriosis significantly decreases vesicle development, suggesting the potential use of epigenetic drugs for endometriosis. The objective of this study was to investigate the …

Coconut Production For Food Security, Economic Development, And Health: A Comparative Study Of Two Communities In Pohnpei, Federated States Of Micronesia, Macmillan Willyander, Nat Tuivavalagi, Ph.D.

Journal of Health Disparities Research and Practice

Coconuts (Cocos nucifera) have been beneficial on many Pacific islands for centuries, including the island of Pohnpei. There is a current effort in Pohnpei to more fully explore the potential of coconuts in raising living standards of the local people. This study explores the status of coconut production in two communities of Pohnpei - a community on the main island of Pohnpei and one on the outer atoll of Ngatik. It is hypothesized that coconut-related activities are less intensive on the outer islands due to a lack of marketing opportunities.

This study involves interviewing community members and 40 …

Exosomes: A Novel Zika Virus Vaccine Candidate, Carlos Furukawa, Pakieli Kaufusi, B.A., M.Sc., Ph.D.

Journal of Health Disparities Research and Practice

With the recent emergence of Zika virus (ZIKV) diseases, increasing global concern has driven the demand for a vaccine. One promising vaccine platform has presented itself in the form of exosomes: a subgroup of extracellular vesicles released by many human cell types that facilitate intercellular communication. The objective of this study is to engineer exosomes that incorporate ZIKV structural proteins into its phospholipid bilayer. Previous studies indicate that CD9 and CD63 proteins are highly enriched in exosomal membranes. From this, it was hypothesized that attaching ZIKV genes to CD9 or CD63 to produce a gene fusion may enable exosomes to …

A Case Study On The Implementation Of Additional Daily Physical Activity Beyond The State-Required Guidelines, Frances Eugenia Phipps

Doctoral Dissertations and Projects

The purpose of this qualitative case study was to provide an in-depth understanding of teachers’, principals’ and educational stakeholders’ viewpoints of students in 3rd, 4th and 5th grades pertaining to the incorporation of additional daily physical activity into the school day above the state-mandated 30 minutes in an elementary school in rural Western North Carolina. Research questions included: How does additional daily physical activity implemented in the school day influence student cognitive development? Why has additional daily physical activity time been incorporated into the school day? How does extended play benefit students beyond cognitive impact? Personal semi-constructed interviews with 11 …

Tumor Microbiome Diversity And Composition Influence Pancreatic Cancer Outcomes, E. Riquelme, Yu Zhang, Liangliang Zhang, M. Montiel, Michelle Zoltan, W. Dong, Pompeyo Quesada, I. Sahin, V. Chandra, Anthony San Lucas, Paul Scheet, Hanwen Xu, Samir M. Hanash, Lei Feng, Jared K. Burks, Kim Anh Do, Christine B. Peterson, Deborah Nejman, Ching Wei D. Tzeng, Michael P. Kim, Cynthia L. Sears

Faculty Publications

Most patients diagnosed with resected pancreatic adenocarcinoma (PDAC) survive less than 5 years, but a minor subset survives longer. Here, we dissect the role of the tumor microbiota and the immune system in influencing long-term survival. Using 16S rRNA gene sequencing, we analyzed the tumor microbiome composition in PDAC patients with short-term survival (STS) and long-term survival (LTS). We found higher alpha-diversity in the tumor microbiome of LTS patients and identified an intra-tumoral microbiome signature (Pseudoxanthomonas-Streptomyces-Saccharopolyspora-Bacillus clausii) highly predictive of long-term survivorship in both discovery and validation cohorts. Through human-into-mice fecal microbiota transplantation (FMT) experiments from STS, LTS, or control …

Issue 332: July 25-August 8, 2019, The Local Voice

The Local Voice

No abstract provided.

Poo Power: Revisiting Biogas Generation Potential On Dairy Farms In Texas, Justin R. Benavidez, Anastasia W. Thayer, David P. Anderson

Applied Economics Faculty Publications

Biogas created from anaerobic digestion on dairy farms can be used to generate electricity, produce coproducts, and reduce reliance on off-farm inputs. We incorporate risk into simulation models representing dairy farms in Texas and demonstrate the profitability of new anaerobic digester installation. Based on this market, results indicate projects that have low investment costs, receive grant support for construction, utilize coproducts, or have some combination of these factors have higher net present value at the end of the study period; however, even with generous grant support and high electricity prices, projects with average investment costs remain unprofitable.

Freedom From Religion Foundati V. County Of Lehigh

2019 Decisions

USDC for the Eastern District of Pennsylvania

Endothelial Iqgap1 Regulates Leukocyte Transmigration By Directing The Lbrc To The Site Of Diapedesis, David P. Sullivan, Prarthana J. Dalal, Fanny Jaulin, David B. Sacks, Geri Kreitzer, William A. Muller

Publications and Research

Transendothelial migration (TEM) of leukocytes across the endothelium is critical for inflammation. In the endothelium, TEM requires the coordination of membrane movements and cytoskeletal interactions, including, prominently, recruitment of the lateral border recycling compartment (LBRC). The scaffold protein IQGAP1 was recently identified in a screen for LBRC-interacting proteins. Knockdown of endothelial IQGAP1 disrupted the directed movement of the LBRC and substantially reduced leukocyte TEM. Expression of truncated IQGAP1 constructs demonstrated that the calponin homology domain is required for IQGAP1 localization to endothelial borders and that the IQ domain, on the same IQGAP1 polypeptide, is required for its function in TEM. …

Toxoplasma Gondii Infection Drives Conversion Of Nk Cells Into Ilc1-Like Cells, Eugene Park, Swapneel Patel, Qiuling Wang, Prabhakar Andhey, Konstantin Zaitsev, Sophia Porter, Maxwell Hershey, Michael Bern, Beatrice Plougastel-Douglas, Patrick Collins, Marco Colonna, Kenneth M. Murphy, Eugene Oltz, Maxim Artyomov, L David Sibley, Wayne M. Yokoyama

Open Access Publications

Innate lymphoid cells (ILCs) were originally classified based on their cytokine profiles, placing natural killer (NK) cells and ILC1s together, but recent studies support their separation into different lineages at steady-state. However, tumors may induce NK cell conversion into ILC1-like cells that are limited to the tumor microenvironment and whether this conversion occurs beyond this environment remains unknown. Here, we describe

Modeling And Finite Element Simulations Of Phase Change Memory Materials And Devices, Jake Scoggin

Doctoral Dissertations

I simulate phase change including stochastic nucleation and growth of discrete grains with a finite element framework which captures the latent heat of phase change and heterogeneous melting. I model the electrical conductivity, thermal conductivity, Seebeck coefficient, and specific heat in TiN, SiO₂, and the face centered cubic and amorphous phases of Ge₂Sb₂Te₅ as well as the thermal boundary conductance at interfaces of these materials over the temperatures and fields encountered during phase change memory device operation. Simulations show reset, set, and read of phase change memory devices including mushroom cells, encapsulated pillar …

Vickers V. Idaho Board Of Veterinary Medicine Clerk's Record Dckt. 47270

Idaho Supreme Court Records & Briefs, All

No abstract provided.

Advances In Management Of Neuropsychiatric Syndromes In Neurodegenerative Diseases, Jeffrey Cummings, Aaron Ritter, Kasia Rothenberg

School of Medicine Faculty Research

Purpose of Review Neuropsychiatric syndromes (NPS) are common in neurodegenerative disorders (NDD). This review describes the role of NPS in the diagnosis of NDD, criteria for the diagnosis of NPS, management of NPS, and agents in clinical trials for NPS. Recent Findings NPS play an increasingly important role in the diagnosis of NDD. Consensus diagnostic criteria have evolved for psychosis, depression, agitation, and apathy in NDD. With one exception—pimavanserin is approved for the treatment of hallucinations and delusions in Parkinson’s disease—there are no drugs approved by the FDA for treatment of NPS in NDD. Trials show that atypical antipsychotics reduce …

Engineering Dna Recognition And Allosteric Response Properties Of Tetr Family Proteins By Using A Module-Swapping Strategy, Rey P. Dimas, Benjamin R. Jordan, Xian-Li Jiang, Catherine Martini, Joseph S. Glavy, Dustin P. Patterson, Faruck Morcos, Clement T.Y. Chan

Biology Faculty Publications and Presentations

The development of synthetic biological systems requires modular biomolecular components to flexibly alter response pathways. In previous studies, we have established a module-swapping design principle to engineer allosteric response and DNA recognition properties among regulators in the LacI family, in which the engineered regulators served as effective components for implementing new cellular behavior. Here we introduced this protein engineering strategy to two regulators in the TetR family: TetR (UniProt Accession ID: P04483) and MphR (Q9EVJ6). The TetR DNA-binding module and the MphR ligand-binding module were used to create the TetR-MphR. This resulting hybrid regulator possesses DNA-binding properties of TetR and …

Ruff At Roesch: Student Staffer Training 4 Paws Pup, Matt Mckinley

University Libraries Blog Archive

With a library student worker as her companion, Nutella, a golden retriever puppy, is training to become a service animal with 4 Paws for Ability, a nonprofit based in Xenia, Ohio.

Effects Of Adrenergic Or A Combination Of Adrenergic And Opioid Drugs On Assessments Of Insulin Sensitivity In Mares, Lauren Kerrigan

LSU Master's Theses

Excitement is a problem when conducting endocrine tests on fractious horses. Epinephrine (EPI), for example, was shown to obliterate the insulin-induced decrease in blood glucose concentrations. Sedation may be a solution; however, perturbation of results may preclude useful information. The objectives of the four experiments presented herein were 1) to determine the effects of EPI on insulin response to glucose infusion (IR2G), 2) to assess the effects of the α-adrenergic sedative, detomidine (DET), alone or in combination with the opioid agonist, butorphanol (BUT), on IR2G and glucose response to insulin (GR2I), and 3) to assess the effects of BUT alone …

Coronary Heart Disease, Hypertension And Use Of Biomass Fuel Among Women: Comparative Cross-Sectional Study, Zafar Fatmi, Georgia Ntani, David Coggon

Community Health Sciences

Objectives: To explore the associations of hypertension and coronary heart disease (CHD) with use of biomass fuel for cooking.
Design: Comparative cross-sectional study.
Setting: Rural villages in Sindh, Pakistan.
Participants: Women aged ≥40 years who had used biomass fuel for cooking for at least the last year (n=436), and a comparison group (n=414) who had cooked only with non-biomass fuel during the last year were recruited through door-to-door visits. None of those who were invited to take part declined.
Primary and secondary outcome measures: Hypertension was determined from blood pressure measurements and use of medication. CHD was assessed by three …

Information Diffusion And Social Norms Are Associated With Infant And Young Child Feeding Practices In Bangladesh, Phuong H. Nguyen, Edward A. Frongillo Jr., Sunny S. Kim, Amanda A. Zongrone, Amir Jilani, Lan Mai Tran, Tina Sanghvi, Purnima Menon

Faculty Publications

Background

Interaction within mothers’ social networks can theoretically diffuse messages from interventions and campaigns into norms and practices for infant and young child feeding (IYCF).

Objectives

We hypothesized that mothers’ social networks, diffusion of information, and social norms differed in intensive [intensive interpersonal counseling (IPC), community mobilization (CM), and mass media (MM)] compared with nonintensive (standard IPC and less-intensive CM and MM) intervention areas, were associated with IYCF practices, and partly explained practice improvement.

Methods

We conducted household surveys at endline in 2014 and follow-up in 2016 (n = ∼2000 each round). We used multiple regression to test differences …

Predicting Pelargonium Responses To Climate Change In A Biodiversity Hotspot Throughout South Africa, Tanisha Marie Williams

Doctoral Dissertations

Climate change is causing major shifts in species distributions, which fundamentally alters the species composition and functioning of biological communities across the globe. Projections suggest that by 2100 up to one of every six species will become extinct. Such drastic changes will have significant impacts on biodiversity patterns and ecosystem functioning. Ecologists are faced with the pressing work of trying to understand how plants will respond to changing and increasingly stressful environments. To predict the long-term effects and magnitude of species responses, it is imperative that species adaptive responses are understood across the entirety of their geographic ranges. My dissertation …

What We (Don’T) Know About Global Plant Diversity, William K. Cornwell, William D. Pearse, Rhiannon L. Dalrymple, Amy E. Zanne

Ecology Center Publications

The era of big biodiversity data has led to rapid, exciting advances in the theoretical and applied biological, ecological and conservation sciences. While large genetic, geographic and trait databases are available, these are neither complete nor random samples of the globe. Gaps and biases in these databases reduce our inferential and predictive power, and this incompleteness is even more worrisome because we are ignorant of both its kind and magnitude. We performed a comprehensive examination of the taxonomic and spatial sampling in the most complete current databases for plant genes, locations and functional traits. To do this, we downloaded data …

Newsroom, Georgia Southern University

Newsroom (2006-2023)

• Georgia Southern student, faculty research shows surprising findings about pet ownership, potential health risks for women
• Georgia Southern helping rural teachers introduce renewable energy into classrooms