Digital Commons Network^™

Theories Of Perception In Renaissance Humanism, John Shannon Hendrix

Architecture, Art, and Historic Preservation Faculty Publications

The hypostases of being consist of the terrestrial world of corporeal forms, dense, intertwined and in shadow; then the rationalization of the corporeal forms in the angelic mind; and finally the resolution of the forms in their absolute archetypal unity. The hypostases of being are modelled in the Universal Figure of Nicolas Cusanus, with the three figures of body, soul and mind inscribed in each of the three levels of the hierarchy, containing the nine choruses of Pseudo-Dionysius in the celestial hierarchies, representing the structure of the universe, as illustrated in a diagram, “Quator dictarum Monadum Schematica explicatio,” in Kircher’s …

Blast From The Past: The Effects Of Battlefield Exposure On War Veterans, Elizabeth Toigo

The Synapse: Intercollegiate science magazine

No abstract provided.

Language And Perception In Plotinus, John Shannon Hendrix

Architecture, Art, and Historic Preservation Faculty Publications

I will argue that in the thought of Plotinus, how we perceive the world around us is determined by how we use language.

Robert Grosseteste: Optics And Perception, John Shannon Hendrix

Architecture, Art, and Historic Preservation Faculty Publications

In De Luce seu de inchoatione formarum, the treatise on light written between 1225 and 1228, Grosseteste explains that light is the first corporeal form, the origin of matter.

The Imaginary And Symbolic Of Jacques Lacan, John Shannon Hendrix

Architecture, Art, and Historic Preservation Faculty Publications

The principal categories of Lacanian psychoanalysis in the structuring of the psyche are the imaginary, the symbolic, and the real. The imaginary (imaginaire) refers to perceived or imagined images in conscious and unconscious thought, sensible and intelligible forms; picture thinking (Vorstellung), dream images or manifest content, and conscious ego in discursive thought. The symbolic (symbolique) refers to the signifying order, signifiers, in language, which determine the subject; it refers to the unconscious, and the intellectual, the logos endiathetos and the logos prophorikos. It is the relation between the imaginary and symbolic in conscious and …

Perspectives Winter/Spring 2019, Nova Southeastern University

Perspectives

Dr. Pallavi Patel College of Health Care Sciences

A Synthetic Agonist To Vasoactive Intestinal Peptide Receptor-2 Induces Regulatory T Cell Neuroprotective Activities In Models Of Parkinson's Disease, R. Lee Mosley, Yaman Lu, Katherine E. Olson, Jatin Machhi, Wenhui Yan, Krista L. Namminga, Jenell R. Smith, Scott J. Shandler, Howard Gendelman

Journal Articles: Pharmacology & Experimental Neuroscience

A paradigm shift has emerged in Parkinson's disease (PD) highlighting the prominent role of CD4⁺ Tregs in pathogenesis and treatment. Bench to bedside research, conducted by others and our own laboratories, advanced a neuroprotective role for Tregs making pharmacologic transformation of immediate need. Herein, a vasoactive intestinal peptide receptor-2 (VIPR2) peptide agonist, LBT-3627, was developed as a neuroprotectant for PD-associated dopaminergic neurodegeneration. Employing both 6-hydroxydopamine (6-OHDA) and α-synuclein (α-Syn) overexpression models in rats, the sequential administration of LBT-3627 increased Treg activity without altering cell numbers both in naïve animals and during progressive nigrostriatal degeneration. LBT-3627 administration was linked to …

Autonomic And Redox Imbalance Correlates With T-Lymphocyte Inflammation In A Model Of Chronic Social Defeat Stress, Cassandra M. Moshfegh, Safwan K. Elkhatib, Christopher W. Collins, Allison J. Kohl, Adam J. Case

Journal Articles: Cellular & Integrative Physiology

Patients diagnosed with post-traumatic stress disorder (PTSD) are at a significantly elevated risk of developing comorbid inflammatory conditions, but the mechanisms underlying this predilection remain unclear. Our previous work has shown that T-lymphocytes exposed to elevated levels of norepinephrine (NE) displayed a pro-inflammatory signature reminiscent of an autoreactive phenotype. With this, we hypothesized that the increased sympathetic tone observed during psychological trauma may be promoting pro-inflammatory T-lymphocytes, which causes a predisposition to comorbid inflammatory conditions. Here, we examined the consequences of psychological trauma on splenic T-lymphocytes using a mouse model of repeated social defeat stress. Social defeat led to anxiety-like …

The Diverging Right(S) To Bear Arms: Private Armament And The Second And Fourteenth Amendments In Historical Context, Alexander Gouzoules

Faculty Publications

This article compares the historical evolution of the social understanding of private armament with contemporary legal doctrine on the right to bear arms. The District of Columbia v. Heller decision, which held that the Second Amendment protects a personal right to self-defense, and the McDonald v. City of Chicago decision, which held the Second Amendment to be incorporated by the Fourteenth Amendment, both turned on extensive historical analysis. But by reading a broad “individual right to self-defense” into both the Second and Fourteenth Amendments, the Court assumed continuity between the social understandings at the time of these amendments’ respective ratifications. …

Perceived Threat To Paternity Reduces Liklihood Of Paternal Provisioning In House Wrens, Rachael A. Disciullo, Charles F. Thompson, Scott K. Sakaluk

Faculty Publications – Biological Sciences

Biparental care is a critical and, occasionally, unequally shared obligation that ensures that young survive to maturity. Such care may be complicated in systems in which one parent, typically the male, is unsure of his genetic relatedness to the young. Males may reduce paternal provisioning when full paternity is not assured, as occurs in mating systems in which females engage in extrapair copulations. Moreover, other factors independent of extrapair matings, such as male personality traits, likely also affect the level of paternal care. In this study, we determined the effect of a paternity threat event (i.e., a conspecific or a …

She Could Steal, But She Could Not Rob: Punishment Inflation In Burglary Statutes Nationwide, Candace Mccoy, Phillip M. Kopp

Journal of Legislation

No abstract provided.

Back To The Farm: A Call To Re-Invigorate New York City's Biosolid Program, Brendan Collins

Journal of Legislation

No abstract provided.

Group-Based Physical Activity Trajectories In Children Transitioning From Elementary To High School, Russell R. Pate

Health and Kinesiology Faculty Publications

Background: Physical activity has been observed repeatedly to decline as children transition into adolescence; however, few studies have explored the possibility that sub-groups of children experience unique patterns of change during this transition. The purpose of this longitudinal study was to examine the physical activity trajectories in clusters of youth transitioning from 5th to 11th grade.

Methods: Participants (n = 652) were recruited as 5th graders (ages 10–12 years) from elementary schools (n = 21) in two school districts. Demographic, anthropometric, and physical activity data were collected once per year when children were in 5th, 6th, 7th, 9th, …

Lexical Derivation Of The Pint Taxonomy Of Goals: Prominence, Inclusiveness, Negativity Prevention, And Tradition, Benjamin M. Wilkowski, Adam Fetterman, Shaun K. Lappi, Laverl Z. Williamson, Elizabeth Ferguson Leki, Emilio Rivera, Brian P. Meier

Psychology Faculty Publications

What do people want? Few questions are more fundamental to psychological science than this. Yet, existing taxonomies disagree on both the number and content of goals. We thus adopted a lexical approach and investigated the structure of goal-relevant words from the natural English lexicon. Through an intensive rating process, 1,060 goal-relevant English words were first located. In Studies 1-2, two relatively large and diverse samples (total n = 1,026) rated their commitment to approaching or avoiding these goals. Principal component analyses yielded 4 replicable components: Prominence, Inclusiveness, Negativity prevention, and Tradition (the PINT Taxonomy). Study 3-7 (total n = 1,396) …

Cosechando Justicia: Café De Comercio Justo, Sustentabilidad Y Sobrevivencia, Daniel Jaffee

Sociology Faculty Publications and Presentations

El comercio justo es un mercado alternativo internacional en rápido crecimiento que busca promover una mayor justicia social para los pequeños productores y ofrecer mejores precios para sus productos. Este estudio de los productores de café en México es el primero en analizar detalladamente los beneficios sociales, económicos y medioambientales del comercio justo. Basado en un extensa investigación etnográfica en comunidades indígenas Zapotecas de la Sierra Juárez de Oaxaca, Cosechando Justicia explora vívidamente la vida de los socios de la cooperativa Michiza, cuyo café orgánico es vendido en el mercado internacional de comercio justo, comparándola con la de los productores …

Nationalizing Trips: An Examination Through Exceptions, 18 J. Marshall Rev. Intell. Prop. L. 285 (2019), Evan Tallmadge

UIC Review of Intellectual Property Law

What should not be patentable? The Agreement on Trade-Related Aspects of Intellectual Property Rights (“TRIPS”) codifies certain categories of subject matter that nations can exclude from patent protection. This Article examines how nations have interpreted these exclusions through an analysis of their national manuals of patent examining procedure and more importantly what explicit exceptions to patentability these countries have listed. The Article proceeds to analyze both the similarities and differences in approaches towards exclusions that attempt to ban the same subject matter from patentability and differences in what countries have chosen to bar from patenting. The Article concludes with an …

2019-2020 Risd Course Announcement, Risd Registrar's Office, Risd Archives

RISD Course Catalogs / Announcements

No abstract provided.

Effect Of Sulfobutyl Ether Β-Cyclodextrins On Oral And Dermal Pharmacokinetics Of Drugs, Vijay Kumar Shankar

Electronic Theses and Dissertations

Silymarin is an extract of Milk Thistle, major constituents are taxifolin, silychristin, silydianin, silybin A, silybin B, isosilybin A and isosilybin B. The in vitro, preclinical and clinical studies have demonstrated silymarin possesses hepatoprotective, anticancer, hypocholesterolemic, cardioprotective effect and dermatological beneficial effect (treatment of UV induced erythema, melanoma, non-melanoma skin cancer, rosacea, melasma, vitiligo and psoriasis) both individually and collectively. Solubility enhancement of silymarin constituent is utmost important to increase bioavailability and to improve drug developability property. The solubility of silymarin in water was enhanced by SBE-β-CD by conventional and heating method, heating method was found to be more efficient …

The Role Of Dunc13 In Ethanol Tolerance, Yusuke Wachi

Electronic Theses and Dissertations

Although the effects of ethanol on presynaptic activity have been studied, the molecular mechanisms and the changes in gene expression which are responsible for inducing ethanol tolerance are unclear. Munc13-1 is an active-zone protein that is essential for presynaptic vesicle fusion. This protein interacts with vesicle fusion machinery at presynaptic active zones in the mammalian brain. The C1 domain of Munc13-1 binds diacylglycerol (DAG), which helps membrane localization of this protein and promotes vesicle fusion, facilitating synaptic vesicle release. Previously, it was shown that ethanol binds to the C1 domain of Munc13-1 in vitro at concentrations below 100 mM (Das …

Developing Zebrafish As An In Vivo Model To Screen Compounds For Anti-Cancer Activity In Human Breast Cancer, Trisha Dhawan

Electronic Theses and Dissertations

Breast Cancer (BC) is the most frequently diagnosed cancer; 1:8 women are at risk of developing BC in her lifetime. Cancer metastasis causes the majority of deaths in BC patients. Moreover, side effects of traditional chemotherapeutic drugs (TCD) impair the quality of life of these patients. Discovery and development of safe and effective new therapies is imperative for the treatment of BC and targeting metastasis. The goal herein is to further expand the applicability of in vivo xenotransplantation of human BC cells in transgenic zebrafish to screen potential chemotherapeutics for toxicity and efficacy. For xenotransplantation, MCF-7, BT-474, and MDA-MB-231 BC …

Effect Of Solvent Interaction & Soluble Microneedles On Skin Permeability To Drug Molecules, Abhijeet Maurya

Electronic Theses and Dissertations

Skin forms a formidable barrier protecting the human body from external environmental rigors and excessive loss of water; maintaining equilibrium. The barrier properties of the skin can be attributed to its unique macromolecular organization and morphology. As a route for drug administration, skin presents a large surface area and can be used for both systemic and localized targeted drug delivery applications offering several advantages over conventional drug therapy; avoidance of first pass metabolism, patient compliance, sustained or controlled delivery for an extended period, to name a few. However, the organized structure of the skin, since intended to prevent entry of …

Novel Applications Of Hot-Melt Extrusion Technology In Trans-Buccal And Topical Drug Delivery Systems, Nicole Mendonsa

Electronic Theses and Dissertations

As the buccal route of administration can avoid the first pass effect, the bioavailability of drugs that are metabolized in the liver can be increased through this route. Few studies have been conducted using oleic acid as a permeation enhancer in any trans-buccal dosage form. The objective of this study was to develop a buccal tablet using two concentrations of oleic acid for a model drug (Ondansetron) via melt extrusion technology and investigate the effects of oleic acid on the physicochemical properties of the tablet. Formulations consisting of the active drug (ondansetron hydrochloride), polymers and oleic acid were prepared by …

Explication Of Moral Disgust: Assessing Physiological And Behavioral Responses To Disgust Eliciting Videos, Sarah Michelle Scott

Electronic Theses and Dissertations

Results indicate a significant self-reported disgust response among core animal reminder and contamination domains whereas the moral domains elicited both anger and disgust. Physiologically no change was measured in skin conductance; heart rate decrease in response to animal reminder contamination community and autonomy video clips. Significant behavioral avoidance was demonstrated when presented with the core and animal reminder video clips. Further when measuring facial muscle activation the levator labii was significantly activated in response to the core video clip but no others. The current study highlights the difficulty in establishing characteristic responses to disgust stimuli especially within the moral domain. …

Going To Bat: Assessing Disgust Sensitivity And Related Factors In Behavioral Avoidance, Molly E. Wickenhauser

Electronic Theses and Dissertations

The present study used archival data (N = 194) consisting of responses from a battery of questionnaires and data from eight behavioral avoidance tasks (BATs). Correlational analyses demonstrated that disgust sensitivity, anxiety sensitivity, state disgust and anxiety ratings during BATs, and behavioral avoidance on BATs were significantly correlated. Higher disgust sensitivity and behavioral avoidance was also associated with being female. Unexpectedly, emotion dysregulation was not correlated with disgust sensitivity or behavioral avoidance. Next, a series of hierarchical multiple linear regressions indicated that the contamination disgust domain appeared to be the strongest predictor of behavioral avoidance on core- and contamination-related BATs, …

Effects Of Impoundments On The Community Assemblage And Gene Flow Of Stream Crayfishes, Zanethia Choice Barnett

Electronic Theses and Dissertations

Dams and their impoundments block movement of stream organism and change stream physiochemical properties, which subsequently changes biological assemblages and creates barriers to gene flow. While changes in species assemblages and gene flow have been assessed for numerous impoundments and stream organisms, no study has assessed the effects of large impoundments on crayfish assemblages and population genetic diversity and connectivity. I examined the physiochemical, biological, and genetic effects of impoundments on crayfishes. Between May 2015 and August 2017, I sampled multiple sites up- and downstream of three impounded streams, and along the lengths of two unimpounded streams, in the Bear …

Local Regulation Of Charitable Solicitation, Joseph Mead

Law Faculty Articles and Essays

Most discussions of the policy context for nonprofits in the United States focus on federal or state restrictions. Fundraising charities, however, must comply not only with myriad state requirements but an uncertain number of local requirements as well. Based on a survey of the largest cities in the United States, I find that all of these cities have some restrictions on charitable solicitation. Several of the cities also impose extensive registration requirements and other restrictions. These findings highlight the need for nonprofits to be aware of local regulation of their activities.

Contracting For Human Rights: Looking To Version 2.0 Of The Aba Model Contract Clauses, Sarah Dadush

American University Law Review

No abstract provided.

Rethinking Religious Objections (Old-Testament Based) To Same-Sex Marriage, Doron M. Kalir

Law Faculty Articles and Essays

In Obergefell v. Hodges, the Supreme Court closed the door on one issue only to open the floodgates to another. While recognizing a constitutional right for same-sex marriage, the Court also legitimized religious objections to such unions, practically inviting complex legal challenges to its doors. In doing so, the Court also called for an "open and searching debate" on the issue. This Article seeks to trigger such debate.

For millennia, objections to same-sex marriage were cast in religious and moral terms. The Jewish Bible ("Old Testament"), conventional wisdom argues, provided three demonstrable proofs of the Bible's abhorrence of same-sex …

Linking Microbial Community Structure And Ecosystem Functions In Acidic Soil From Pennsylvania, Usa, Madison T. James, Sophia T. Farrisi, Shreya Shah, Vishal Shah

Sustainability Research & Creative Activities Grants Reports

Microorganisms play a critical role in the structure and functioning of soil ecosystems. Within acidic soil across the northeastern United States and Canada, we have little understanding of the microbial diversity present and its relationship to the biochemical cycles. The current study is aimed at understanding the taxonomical and functional diversities in the acidic soil obtained from near various types of trees, how the diversities change as a function of depth, and the linkage between taxonomical and functional diversities. From eight sampling locations, soil samples were collected from three horizons (depths). The three depths were 0-10 cm (A), 11-25 cm …

Federal Women, Incivility, Job Satisfaction, And Job Stress, Wanda Harris Pemberton

Walden Dissertations and Doctoral Studies

Incidents of incivility in the workplace have continued to increase in frequency. Workplace incivility impacts the health and well-being of those who experience or witness the behavior and impacts morale, levels of engagement, attendance, retention, and overall organizational health. Researchers have explored the damage caused by workplace incivility, but few have focused on the impact of incivility among federally employed women. The purpose of this quantitative, correlational study was to examine the relationship between incivility, job satisfaction, and job stress among women working in the federal sector. The affective events theory framed this study. Online surveys were used to capture …