Digital Commons Network^™

Profound Opioid And Medetomidine Withdrawal: A Case Series And Narrative Review Of Available Literature, Phil Durney, Elise Paquin, Gamal Ftizpatrick, Drew Lockstein, Tareva Warrick-Stone, Do, Maeve Montesi, Sejal Patel, Jamal Rashid, Oluwarotimi Vaughan-Ogunlusi, Kelly Goodsell, Jennifer L. Kahoud, Christopher Martin, Keira Chism, Paul Goebel, Karen Alexander, Dennis Goodstein, Kory S. London

Division of Internal Medicine Faculty Papers & Presentations

Medetomidine, a potent central acting α2 agonist, has emerged as a fentanyl adulterant in the non-medical opioid supply. Its use has been linked to a novel withdrawal syndrome that is often resistant to conventional treatment protocols. Four cases are presented exemplifying extreme, but increasingly common forms of this withdrawal syndrome. A literature review is provided demonstrating both the paucity of available literature as well as potential avenues for treatment and future research. As adulterants continue to proliferate in the illicit drug supply, clinicians should anticipate atypical withdrawal phenotypes and consider early intervention.

The Grizzly, October 23, 2025, Renee Washart, Julia Picklo, Nathaniel Nerone, Erin Ewing, Caitlin Cunnane, Kate Adams

Ursinus College Grizzly Newspaper, 1978 to Present

Opportunities in Motion • Spooky Spectacles and Enchanting Art • In the Blood: A Visceral Scarlet Letter Stage Adaptation • The MAA Fortnightly Question • Greetings From Ireland • The Best and Worst of C-Store (In My Humble Opinion) • An Injured Athlete's Experience: Emma Reinert • Bears' Players of the Week • Field Hockey Fights to Keep Season Alive

Spectator 2025-10-23, Editors Of The Spectator

The Spectator

No abstract provided.

Evaluation Of Interleukins 35 And 39 Levels In Women Infected With Cytomegalovirus, Maryam Adnan Juma, Zahra’A Abdulraheem Ahmed

Baghdad Science Journal

Cytomegalovirus (CMV) is a common latent virus that can cause severe disease in immunocompromised individuals and pregnant women. Interleukins (ILs) are crucial for cell-to-cell communication and facilitate precise regulation of the immune response. The current study aimed to evaluate serum IL-35 and IL-39 levels in Iraqi women with CMV, particularly in pregnant women, and investigate their potential involvement in CMV infection and pregnancy. Serum samples were obtained from 115 women (age range:15–29 years), including CMV-infected pregnant women, uninfected pregnant women, CMV-infected non-pregnant women, and healthy non-pregnant women. IL-35 and IL-39 levels were measured using ELISA kits. Statistical analyses were performed …

Sensitive Cloud Point Extraction Method For Determination Of Salbutamol Sulfate In Pharmaceutical Dosage Forms, Ghadah Fadhil

Baghdad Science Journal

The cloud point extraction (CPE) methodology was utilized to produce a simple, highly sensitive, and environmentally friendly method for preconcentrating and evaluating salbutamol sulfate (SAL) in pharmaceutical dosage forms. Triton X-114 was used as a surfactant to recover the product result from the diazotization coupling between SAL and diazotized 2, 4-dichloroaniline (DCA) by the cloud point extraction process. The product was extracted with non-ionic surfactant micelles and then spectrophotometrically detected at a wavelength of 445 nm. Under ideal conditions, the calibration curve’s linearity (r = 0.9947) ranged from 0.1 to 5.0 μg. mL^–1 of SAL. The results showed …

Using An Old Assay In New Ways: Differential Scanning Calorimetry Characterization, Quantification, And Interaction Analysis Of Whey Proteins, Charity Conlin Jennings

Theses and Dissertations

Whey proteins including β-Lactoglobulin, α-Lactalbumin, Immunoglobulin-G, Serum Albumin, Lactoferrin, and Lactoperoxidase each have unique biological properties spanning anti-bacterial, anti-fungal, and anti-viral activities as well as deliver essential nutrients to the human body. In the past decade, there has been a large focus on extracting these individual proteins for their use in foods and supplements. In order to best extract these proteins and prepare them properly in foods and supplements, an understanding of how they behave and denature in different environments is necessary. However, there is insufficient knowledge of their thermodynamic properties and potential interactions in varying conditions. Additionally, there are …

Object Play In Tsimane Children: Implications For Sex-Specific Division Of Labour, Ava Moser, Michael D. Gurven, Hillard Kaplan, Benjamin C. Trumble, Jonathan Stieglitz, Paul Hooper, Daniel Cummings, Adrian Jaeggi, Kathelijne Koops

ESI Publications

Sex-specific division of labour and the associated use of different subsistence techniques by males (e.g. hunting) and females (e.g. gathering) has played an important role in shaping human societies. Skills needed in adulthood are practiced in play during childhood and object play has been proposed to foster tool-use skills necessary for adult subsistence techniques. Here, we investigated sex differences in the ontogeny of object play in Tsimane children in Bolivia to understand its potential role in shaping gender-specific adult roles. We used observational data (>80,000 scan samples) from nine Tsimane communities collected between 2002 and 2007. We analysed age …

The Cowl - V. 89 N. 5 - October 23, 2025

The Cowl

The Cowl - student newspaper of Providence College. Vol. 89 No. 5 - October 23, 2025. 20 pages.

Synthesis, Characterization, And Studying The Biological Activity, Thermal, And Physical Properties With The Evaluation Of Pharmaceutical Release Of New Derivatives From Polyvinylpyrrolidone, Zahraa Mokhtar, Sana Hitur Awad

Baghdad Science Journal

In this research drug polymers, have been prepared by substituting drugs to polymers backbone, which raised interest as a result of the benefits systems possesses, which includes the gradual release of the application of the drug, ease of application, delivery of the drugs in certain (specific) local, prolong the period of drug douse, reduce the potential and common side effects, and decrease the toxicity. This work included ring opening of PVP with ethylene glycol then substitution with different drugs (Salbutamol and Ribavirin, Phenylephrine, Theophylline, Sulfamethoxazole). All prepared drug polymers were identified by FT-IR,¹H-NMR, and UV. Spectroscopes, thermal analysis …

Synthesis Of New Compounds From Pyridazine Derivatives, And Preliminary Pharmacological Study, Mohammed Hasan Al-Dahlaki, Aya H. Mohammed

Baghdad Science Journal

There has been an increasing interest in the chemistry of pyridazine derivatives because of their biological significance. Pyridazine has been reported to possess variety of biological activities like antidiabetic, anticancer, anti-AIDS, anti-inflammatory, anticonvulsant and antimicrobial, insecticidal etc. In our study, pyridazine derivatives were synthesized by starting with paracetamol, also known as para hydroxy acetanilide, which does not require a prescription. The reaction involved the use of metallic sodium and methanol as a solvent, resulting in the formation of para-hydroxy acetanilide sodium salt (p-hydroxy acetanilide sodium salt). Subsequently, compound p-hydroxy acetanilide sodium salt was reacted with 2-chloro ethyl acetate in Dimethylformamide …

Synthesis, Spectral Characterization, Cytotoxic Assay, And Antimicrobial Evaluation Studies Of Some Transition Metal Complexes Of Schiff Base Derived From Amoxicillin, Alya’A J. Ahmed, Amaal S. Sadiq, Enaam Fadil Mousa, Mahasin Alias

Baghdad Science Journal

Four metal complexes of Schiff base ligand were prepared. To characterize both the ligand and the metal complexes, various techniques were employed, including elemental analysis, FT-IR spectroscopy, UV-Vis spectroscopy, molar conductivity measurements, magnetic moment determination, melting point, mass spectroscopy, ¹H-NMR and ¹³C-NMR spectroscopy. The results showed that the metal complexes formed have the formula [M(L)₂Cl₂]Cl_(n).H₂O, where L= Schiff base ligand and M=Cr(III), Rh(III), Pt(IV) and Au(III), n = 1, 2. Based on spectroscopic analysis, coordination with metal ions involves the ’N’ donor atom of N atoms of the imine and …

Study The Effect Of Saponin And Terpene From Alcoholic Extract Of Bacopa Monnieri Plant Cultivated In Iraq On Some Biological Aspects Of Drosophila Melanogaster Meigen (1830) (Diptera:Drosophilidae), Ruwaida A. Abd Al-Hussien, Soolaf A. Kathiar

Baghdad Science Journal

Drosophila melanogaster is an agricultural insect pest. The female pierces crops and lays eggs. Then, the eggs hatch, after which the larvae begin to develop inside the tissue, feeding on it and destroying it. This study, conducted from 1/11/2023 to 15/12/2024, aims to ascertain the impact of secondary chemicals, in the wild Bacopa monnieri plant cultivated in Iraq on the development of insect life cycle stages using different concentrations (2000, 4000, 6000, 8000 ppm) under laboratory conditions. The data revealed that the eggs had the highest mortality rates at 8000 ppm for saponin and terpene 78.666% and 74% respectively. The …

Silver Nanoparticles As A Potential Control Measure For Some Potyviruses Infecting Faba Bean And Potato Plants, Rehab A. Dawoud, Noha K. El Dougdoug

Baghdad Science Journal

The research investigates the use of silver nanoparticles (AgNPs) as a foliar spray at a concentration (50 mg/ml) on faba bean and potato plants to stimulate systemic acquired resistance (SAR) and suppress bean yellow mosaic virus (BYMV) and potato virus Y (PVY). The application of AgNPs reduced the percentage of virus reduction infection (RI) and disease severity (DS). AgNPs (50 mg/ml) was more effective on BYMV-infected faba bean (9.75 and 10.50) followed by PVY-infected potato (14.50 and 18.25) for the percentage of reduction infection and disease severity respectively. The mechanism of AgNPs involves binding to viral protein coats, aggregating virus …

Mold Exposure And Cognitive Health During Menopausal Transitions: A Quantitative Analysis Using Secondary Data, Holly Jeannette Burns

Walden Dissertations and Doctoral Studies

Mold exposure and menopausal transition have been independently linked to cognitive decline, yet their interaction among socioeconomically disadvantaged populations has not been well examined. This quantitative study is an exploration of how menopausal transition influences the relationship between mold exposure and cognitive health outcomes among women aged 40 to 60 living in low-income housing in the United States. Bronfenbrenner’s ecological systems theory was used to guide the cross-sectional design using secondary data from the 2005–2006 National Health and Nutrition Examination Survey (NHANES; N = 149). Weighted logistic regression and Hayes’ PROCESS (Models 2 and 4) were used to test associations …

October 23, 2025, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

A Critical Alteration In Enolase Is Identified In One Isolate Of Staphylococcus Aureus To Avoid Host Immunity, Ban M. Abdulhadi, Halah H Al-Haideri

Baghdad Science Journal

The ability of Staphylococcus aureus enolase to cleave plasminogen has been thought to be important for bacterial virulence. The genetic variants of Eno gene sequences were investigated in the present study to assess the pattern of biological diversity of one isolate of S. aureus isolated from patients with diabetic food from Iraqi hospitals. The observed variant’s possible impact in altering the enolase’s binding with its receptor was assessed by docking with plasminogen before and after mutation. Within the locus 791^st, two variations were identified with two different consequences since A>T791 (in S2, S3, S14, and S17) and …

Continuous Flow Injection-Turbidimetric Analysis For Determination Of Cobalt (Ii) Ion In Alloys Using A Microcell With Irradiation Sources At 0–180° Using A Single Solar Cell As A Detector, Murtadha Hadi Athab, Nagham Shakir Al-Awadi

Baghdad Science Journal

A cost-effective and efficient detector was created to conduct thorough turbidimetric measurements by reaction of Co (II) ion with calcium ferro cyanide to form bright green particulate, using the method of continuous flow injection analysis, the use of NAG-5SX1-1D-SSP Analyzer in determining cobalt (II) ion in a test for the validity of the new design. The NAG-5SX1-1D-SSP Analyzer is composed of five irradiation sources of white snow leds having the diameter of 10 mm with one solar cell of 55 mm length, 13.5 mm width. Using a selector switch to select the optimum voltage to be used which was 2.7 …

New Mode For 4 Mm Path Irradiation And One Side Detection At 0–180° For Cu (Ii)Ion Determination In Different Samples Using On-Line Continuous Flow Feed And Simplified, Sensitive, And Portable Photometer, Asma A. Gayed Al-Ani, Nagham S. Turkey Al-Awadie

Baghdad Science Journal

This study presents a rapid, sensitive, and straightforward approach for measuring Cu(II) ions using turbidity continuous flow injection analysis (CFIA) . The method involves reacting Cu(II) ion with calcium Ferro cyanide to produce a brown-red precipitate. To detect the attenuation of incident light as a result of collision on the surfaces of the precipitate particles, the analyzer NAG-SSP-5S-1D was used to measure turbidity at an angle (0–180°).

The linear range of Cu(II) measurements extends from 0.01 to 5 mmol.L^–1 with Correlation Coefficient of 0.9993 and R² % = 99.86 .The limit of detection (LOD) was determined to be …

Azo-Schiff Type Ligands Derived From Curcumin And Their Complexes With Transition Metals, Synthesis, Characterization And Bioactivity Studies, Fatima Rasheed Ali, H. A. Hassan

Baghdad Science Journal

In this work the precursor (W1) 2,2'-((1E,1'E)-(4,4'-diamino-5,5'-dimethyl-[1,1'-biphenyl]Diazene-2,1-diyl-3,3’-diyl)-bis((E)-pyridin-3-yldiazenyl)-[1,1'-biphenyl] or (W2) 3,3'-dimethyl-5,5'-bis((E)-pyridin-3-yldiazenyl)-[1,1'-biphenyl] -4,4'-diamine respectively were obtained from the reaction of 2-aminophenol or 2-aminopyridine with toluidine, respectively. Subsequently, these precursors were used for the synthesis of two ligands using the azo compounds (W1) or (W2) and curcumin to produce [H₄L¹] 4,4',4^'', 4^'''-((1E,1'E,6E,6'E)-((3,3'-bis((E)-(2-hydroxyphenyl)diazenyl)-5,5'-dimethyl-[1,1'-bi phenyl]-4,4'-diyl)bis(azaneylylidene))bis(5-hydroxyhepta-1,6-diene-1,7-diyl-3-ylidene))bis(azaneylylidene))bis(aza -neylylidene))tetrakis(2-methoxyphenol) or [H₂L²] 4,4',4^'',4^'''-((3,3'-dimethyl-,4,4'-diyl)bis- (azaneylylidene))bis(5-hydroxyhepta-1,6-diene-1,7-diyl-3-ylidene))tetrakis(2-methoxyphenol). The prepared ligands were characterized by F.T-I.R, U.V, ¹H-NMR,¹³C-NMR spectroscopy. This work also included the preparation of complexes through the reaction of ligands with the metal …

Development And Integration Of A Molecularly Imprinted Determination Atenolol In Pharmaceutical Samples Based On Solid Phase Extraction, Hamsa S. Omaish, Yehya K. Al-Bayati

Baghdad Science Journal

The current investigation aims to display that bulk polymerization of Atenolol (Ate) can synthesize and store molecular-imprinted polymers (MIP) at room temperature. It is indicated that such an environment has various advantages, including higher sensitivity, lower costs, higher stability, and longer life. To guarantee appropriate adsorption capacity, 0.99:6:20 mmol ratios of template, monomer, and cross-linking agents are employed for polymerization. To start the functional monomer styrene (C8H8) bonding Ethylene glycol dimethacrylate (EGDMA) C10H14O4, the researcher employed benzoyl peroxide (BPO). Accordingly, MIP is created for Atenolol (Ate-MIP), which can be detected for pharmaceuticals employing UV-visible spectrophotometry at 276 nm for drugs. …

Preparation, Characterization, And Studying The Biological Activity Of Schiff Base Metal Complexes Derived From Cephalexin With 3-Methoxy-4-Hydroxy Benzaldehyde, Jenan F. Hassan, Sahar S. Hassan

Baghdad Science Journal

The Schiff base reaction between Cephalexin (CFX). (7R)-3-Methyl-7- (α- D -phenylglycylamino) -3-cephem-4-carboxylic acid (C₁₆H₁₇O₄N₃S) and vanillin C₈H₈O3 [ 3-methoxy -4-mydroxybenzaldehyde] was carried out resulting in ligand C₂₆H₂₇N₃O₆S (L). In turn, reacted with the next metal ions (Cobalt (II), Nickel (II), Copper (II), Zinc (II), and Cadmium (II)), forming stable complexes with unique geometries such as (Octahedral for Ni⁺², Cu⁺², Zn⁺²&Cd⁺², Tetrahedral for Co⁺²). The complexes were identified using …

The Influence Of Solvent, Concentration, And Temperature On The Resolution Of Protons Signals Of 1H Nmr Spectra Of 1,2,3-Triazole-Tethered Glucopyranose, Rasha Saad Jwad

Baghdad Science Journal

Triazoles linked to carbohydrate molecules are one of the most important compounds that have wide applications in the pharmaceutical, biological, and materials science fields. Many of these compounds have been prepared and their structural, chemical, and physical properties have been studied. One of the best techniques used to study and interpret these properties is nuclear magnetic resonance NMR spectroscopy. For this purpose, the simplest glucose-based 1,2,3-triazole derivative 5 has been prepared from D-glucose in four consecutive steps. First, the reaction of glucose with acetic anhydride in the presence of sodium acetate afforded 1,2,3,4,6-penta-O-acetyl-β-D-glucopyranose (2) …

Seasonal Variation Of Phytoplankton And Zooplankton Biomass In Correlation With Physio-Chemical Variables Of Some Water Bodies In Dolly Smaquli, Erbil, Iraq, Sana Kayfi Najmadden, Luay Abdul-Qadir Ali

Baghdad Science Journal

The seasonal variation of phytoplankton and zooplankton groups in correlation with physio-chemical variables has been examined by monthly water samples from eight distinct locations in Smaquli Dam and Streams within Dolly Smaquli in Erbil city, Iraq. The sampling time spans from September 2021 to August 2022. Nineteen physical and chemical variables were examined including Air and water temperature, Electrical conductivity (EC), Total dissolved solids (TDS), Turbidity, pH, Dissolved oxygen (DO), Biochemical oxygen demand (BOD₅), Total Alkalinity, Total Hardness, Nitrite (NO₂), Nitrate (NO₃), Reactive phosphate (PO₄), Ca⁺², Mg⁺², Na …

Cadmium Removal From Aqueous Solutions Facilitated By Biochar Derived From Active Sewage Sludge, Aya L. Khalil, Faris H. Al-Ani, Abdul Hameed M. J. Al-Obaidy

Baghdad Science Journal

Biochar was previously confined to agriculture applications, but its utilization has since expanded across various sectors. In this case, sludge acquired from a sewage treatment facility was employed in the production of biochar. The study investigates the adsorption of cadmium in aqueous solution by both untreated biochar and biochar treated with H₃PO₄, examining the influence of adsorbent dosage, contact time, pH, and initial concentration. Phosphorus compounds present on the biochar surface activate it, enhancing cadmium removal compared to untreated biochar. The experimental results showed that the optimal dosage (1000 mg/l) and adsorption rate were significantly affected …

Effect Of The Atmospheric Stability On Wind Energy Density Using Similarity Theory, Jafar Mohammed Khadir, Basim Abdulsada Al-Knani, Ahmed F. Hassoon

Baghdad Science Journal

Atmospheric stability is considered one of the most important factors affecting the increase or decrease in wind speed in the atmosphere and thus affecting the wind energy density. Stability conditions are classified into three categories: unstable, stable, and neutral. This study aims to analyze the stability of the atmospheric conditions in Southern Iraq, specifically in the Ali al-Gharbi region, using the Monin-Obukhov length method. Which includes field data for the wind speed at three altitudes (10 m, 30 m, and 50 m) in 2017. The mean daily and seasonal friction velocities were calculated. Wind speed was calculated for different atmospheric …

Preparation And Characterization Of Polymer Pva Nanofibers Doped With Cuo Using The Electrospinning Technique And Their Industrial Applications, Ahmed J. Noori, Iftikhar M. Ali

Baghdad Science Journal

This work examines the production and analysis of electrospun fibers made from pure and CuO-doped polyvinylpyrrolidone (PVA) polymers. These fibers are then applied to glass and p-type silicon wafers. The ideal parameters for electrospinning were a flow rate of 0.5 ml/h, a voltage of 15 kV, and a distance of 16 cm between the collector and the needle. X-ray diffraction investigation determined that the PVA fibers were amorphous, but the CuO-doped samples had a tetragonal phase. Fourier Transform Infrared Spectroscopy (FTIR) was employed to examine the vibrational properties, modes, and network bonding in the 400 to 4000 cm^–1 spectral …

Kenyon Collegian - October 23, 2025

The Kenyon Collegian

No abstract provided.

Analysis Of Export Competitiveness Of Main Commodities Of North Sulawesi Province, Fahrudin Zain Olilingo, Nur Aini Umar, Ivan Rahmat Santoso

Jurnal Ekonomi dan Studi Pembangunan

This study describes the competitiveness of the main Commodity Exports of North Sulawesi Province. This research is quantitative in nature, using secondary data obtained from the Central Statistics Agency (BPS) in the form of time series with a period of 5 years (2017-2021); the type of data used is the realization of the export value of the four main commodities of North Sulawesi 2017-2021. This research uses Revealed Comparative Advantage (RCA) analysis. The results of this study indicate (1) commodities identified as the most superior commodities of North Sulawesi, namely the commodity Animal/vegetable fats & oils, commodities fish and shrimp, …

Dynamic Competitiveness Of Indonesian Commodities In Major Export Destination, Hertiana Ikasari

Jurnal Ekonomi dan Studi Pembangunan

This study aims to analyze the export competitiveness and market position of the agricultural, manufacturing, and mining sectors in 10 main export destination countries (China, the United States, Japan, India, Singapore, Malaysia, South Korea, Thailand, the Netherlands, and the Philippines). This study uses secondary data sourced from UN COMTRADE for the period of 2013 – 2018. The data is categorized using a 2-digit Harmonized System (HS) classification. This study uses Revealed Comparative Advantage (RCA) and Export Product Dynamics (EPD) analysis tools. The RCA estimation results show the export competitiveness of Indonesia’s agricultural, industrial, and mining products is still weak and …

Deslenguadas: A Photo Essay On The Performative Remembering Of The Impact Of 1940s Americanization Programs In Northern New Mexico, Yvonne M. Montoya, Fawn-Amber Montoya

International Journal on Responsibility

This photo essay captures the dance performance Deslenguadas by choreographer Yvonne Montoya. Deslenguadas, a dance inspired by a writing of the same name published in Gloria Anzaldúa’s Borderlands/La Frontera: The New Mestiza, is a series of three dances – one duet and two solos. The dances in the series explore the impact the forced loss of the Spanish language had on three generations of one nuevomexicano family from the 1940s to the present day. Through dance, movement, projected animation, and spoken word, the dances explore how each generation internalized racism and shame. At the same time, these generations …