Digital Commons Network^™

Analysis Of Atp-Dependent Chaperone Protein Interactions With Misfolded Proteins, Amyloids, And Aggregated Proteins, Shannon May

Open Access Dissertations

Protein aggregation occurs when proteins adopt non-native conformations, exposing hydrophobic surfaces due to misfolding. The exposed regions of two or more proteins associate to form amorphous deposits or highly ordered, stable fibrillar structures called amyloid aggregates. Within the cell, a robust network of proteins safeguard against protein misfolding and aggregation. This network is referred to as the proteostasis network and includes molecular chaperone proteins, co-chaperone proteins, and the ubiquitin proteasome system. Molecular chaperone proteins function in various cellular processes including intracellular transport, oligomeric assembly, and efficient protein folding. Moreover, molecular chaperones are required for folding denatured, misfolded, and de novo …

Essays On Participatory Pricing, Branding, And Consumer Behavior, James Blair

Open Access Dissertations

Participatory pricing consists of unique pricing mechanisms which can provide firms an opportunity to differentiate themselves by allowing consumers to have some influence in setting the price in transactions. Many firms attempting to utilize participatory pricing mechanisms have struggled or even failed in their attempts. Understanding the role of branding with participatory pricing and how it is associated with consumer perceptions, attitudes, and behaviors would be beneficial as more firms attempt to utilize this pricing mechanism. Additionally, examining how giving consumers autonomy in part of the pricing mechanism could provide marketing managers insights into their purchasing preferences and behaviors.

Two …

Experimental And Numerical Simulations For Fluid Body Interaction Problems, Amin Mivehchi

Open Access Dissertations

This dissertation focuses on the experimental and numerical modelling of fluid structure interaction (FSI) problems. The main objective of this work was to develop state-of-art experimental and numerical tools to investigate a variety of Fluid-Structure Interaction problems. This topic is of critical importance to Naval Hydrodynamics and offshore applications, such as in ship design, floating offshore wind platforms and offshore ocean energy systems.

On the experimental modelling of FSI, this dissertation includes detailed of state-of-art hydrodynamic testing tank system for studying biomimetic fluid-structure interaction problems. This system was employed to study unsteady ground effect for pitching and heaving flapping foil …

Condemnation Of Religious Concepts: An Examination Of Chubak's "An Afternoon In Late Autumn" Through Bakhtin's Theory Of Grotesque Realism, Sayed Mohammad Anoosheh, Muhammad Hussein Oroskhan

Khazar Journal of Humanities and Social Sciences

The first traces of modernism in Iranian society can be found in the second decade of twentieth century which was deeply embedded with religious concepts. With regard to Persian literature, short story was developed as a new genre and a sign of modernism of that period by prominent Iranian writers such as Sadeq Hedayat (1903-1951), Mohammad Ali Jamalzadeh (1892-1997) and Sadegh Chubak (1916-1998). In this way a cultural clash was broken out between the traditional religious concepts and the new modern ideas. Among these writers, Chubak was more influenced by the doctrine of modernism. He expressed his message colloquially through …

The Advantages And Disadvantages Of Body Language In Intercultural Communication, Miramar Damanhouri

Khazar Journal of Humanities and Social Sciences

This study is an attempt to explore the advantages and disadvantages of non-verbal communication, specifically body language, in intercultural settings, and the extent to which non-verbal factors contribute to the success of communication , by interviewing 31 English language instructors at the English language Institute at King Abdulaziz University. The instructors came from different cultural backgrounds and their length of stay in Saudi Arabia varies from 1 year to more than 7 years. The findings show that although the main function of body language in an intercultural setting is to clarify meaning when language is a barrier, the difference in …

A Comparison Of The Antimicrobial Efficacy Of Silver Diamine Fluoride And Silver Nitrate: An Ex Vivo Study, Reham M. Alnajjar

Theses and Dissertations

A comparison of the antimicrobial efficacy of silver diamine fluoride and silver nitrate on various cariogenic bacteria: an ex vivo study By: Reham AlNajjar, D.D.S.

A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Dentistry at Virginia Commonwealth University. Virginia Commonwealth University, 2019

Thesis Advisor: William Dahlke, D.M.D., Associate Professor and Chair of Pediatric Dentistry, School of Dentistry

Purpose: The use of silver-based antimicrobials is an emerging method for the treatment of dental caries. In this study, the authors compare the efficacy of the two most prominent silver- based therapeutics, silver diamine …

Change & Maintaining Change In School Cafeterias: Economic And Behavioral-Economic Approaches To Increasing Fruit And Vegetable Consumption, Gregory J. Madden, Joseph Price, Heidi Wengreen

Psychology Faculty Publications

Developing a daily habit of consuming fruits and vegetables (FV) in children is an important public-health goal. Eating habits acquired in childhood are predictive of adolescent and adult dietary patterns. Thus, healthy eating patterns developed early in life can protect the individual against a number of costly health deficits and may reduce the prevalence of obesity. At present, children in the United States (US) under-consume FV despite having access to them through the National School Lunch Program. Because access is an obstacle to developing healthy eating habits, particularly in low-income households, targeting children’s FV consumption in schools has the advantage …

Speaking Their Language: Developing A Bilingual Libguide For Chinese Students, Nathan Elwood Mlis, Maryalice Wade

Library Faculty Publications

This article documents the development of a bilingual English/Mandarin library guide for the Chinese student population of Fort Hays State University. Growing international student populations across the country mean that many university libraries need to customize services for unique student groups. At Forsyth Library of Fort Hays State University we serve over 3600 students from China. We sought to develop further services for this student group. Please note that throughout this paper, when referring to “Chinese language,” we are specifically referencing Standard Mandarin, which is predominant among our Chinese students.

Pesticides: Safe Practices And Personal Protective Equipment (Ppe), Ludovic Tuduri, Caroline Jolly, Danièle Champoux

Fiches

No abstract provided.

Rangewide Tidewater Goby Occupancy Survey Using Environmental Dna, Michael Sutter

Cal Poly Humboldt theses and projects

Rangewide monitoring of fish species is critical for determining status and trends in abundance and distribution; however, implementations of large-scale distribution surveys have generally been constrained by time and cost. This study uses environmental DNA (eDNA) to monitor the presence or absence of two endangered tidewater goby species, the northern tidewater goby (Eucyclogobius newberryi) and the southern tidewater goby (Eucyclogobius kristinae), across their combined geographic range that encompasses the entire California coast (1,350 km).A multi-scale occupancy model designed specifically for eDNA methods was used to account for imperfect detection and to estimate true site occupancy. A …

The Positive Effects On Attitude Among High School Students Towards Students With Autism Spectrum Disorder, Mario Castillo-Urbina

Cal Poly Humboldt theses and projects

Inclusion in the classroom requires that the local education agency provide services (i.e., direct, related) to support each student’s needs. The philosophy guiding inclusion is that these services will allow each student to keep pace or catch-up with his or her typically developing peers (Elkins, Van Kraayenoord, & Jobling, 2003). Students’ attitudes towards their peers with disabilities have been researched and reported through the years however, little work has examined these attitudes in a physical education setting (Archie & Sherrill, 1989; Block & Malloy, 1998; Block & Zeman, 1996; Tripp, French, & Sherrill, 1995). Researchers have reported that individuals avoid …

Key Themes For Identifying Trauma Informed Care Best Practices Within Secondary Education, Mathew Dean Bigham

Cal Poly Humboldt theses and projects

Trauma informed care is a growing trend present today in multiple organizations and institutions. There are a variety of methods, theories, and interventions currently being employed that directly relate to trauma and a trauma informed care approach. This study investigates those trauma and trauma informed care practices to better understand which work, under what conditions, and which ones do not. The information gathered will help to provide a foundation for a sustainable trauma informed care system and approach.

This was a qualitative study utilizing interviews and questionnaires to reveal trauma informed care best practices. Five participants with varying degrees of …

Public Lands, Conservation, And The Possibility Of Justice, Sarah Krakoff

Publications

On December 28, 2016, President Obama issued a proclamation designating the Bears Ears National Monument pursuant to his authority under the Antiquities Act of 1906, which allows the President to create monuments on federal public lands. Bears Ears, which is located in the heart of Utah’s dramatic red rock country, contains a surfeit of ancient Puebloan cliff-dwellings, petroglyphs, pictographs, and archeological artifacts. The area is also famous for its paleontological finds and its desert biodiversity. Like other national monuments, Bears Ears therefore readily meets the statutory objective of preserving “historic and prehistoric structures, and other objects of historic or scientific …

Bloomberg’S Points Of Law: Can They Compete With Headnotes?, Jill Sturgeon

Publications

No abstract provided.

To Sue And Be Sued: Capacity And Immunity Of American Indian Nations, Richard B. Collins

Publications

Can American Indian nations sue and be sued in federal and state courts? Specific issues are whether tribes have corporate capacity to sue, whether a Native group has recognized status as a tribe, and whether and to what extent tribes and their officers have governmental immunity from suit. Tribal capacity to sue is now well established, and federal law has well-defined procedures and rules for tribal recognition. But tribal sovereign immunity is actively disputed.

This Article reviews retained tribal sovereignty in general and summarizes past contests over tribal capacity to sue and their resolution into today’s settled rule. Next is …

Criminal Employment Law, Benjamin Levin

Publications

This Article diagnoses a phenomenon, “criminal employment law,” which exists at the nexus of employment law and the criminal justice system. Courts and legislatures discourage employers from hiring workers with criminal records and encourage employers to discipline workers for non-work-related criminal misconduct. In analyzing this phenomenon, my goals are threefold: (1) to examine how criminal employment law works; (2) to hypothesize why criminal employment law has proliferated; and (3) to assess what is wrong with criminal employment law. This Article examines the ways in which the laws that govern the workplace create incentives for employers not to hire individuals with …

(At Least) Thirteen Ways Of Looking At Election Lies, Helen Norton

Publications

Lies take many forms. Because lies vary so greatly in their motivations and consequences (among many other qualities), philosophers have long sought to catalog them to help make sense of their diversity and complexity. Legal scholars too have classified lies in various ways to explain why we punish some and protect others. This symposium essay offers yet another taxonomy of lies, focusing specifically on election lies — that is, lies told during or about elections. We can divide and describe election lies in a wide variety of ways: by speaker, by motive, by subject matter, by audience, by means of …

The Government's Manufacture Of Doubt, Helen Norton

Publications

“The manufacture of doubt” refers to a speaker’s strategic efforts to undermine factual assertions that threaten its self-interest. This strategy was perhaps most famously employed by the tobacco industry in its longstanding campaign to contest mounting medical evidence linking cigarettes to a wide range of health risks. At its best, the government’s speech can counter such efforts and protect the public interest, as exemplified by the Surgeon General’s groundbreaking 1964 report on the dangers of tobacco, a report that challenged the industry’s preferred narrative. But the government’s speech is not always so heroic, and governments themselves sometimes seek to manufacture …

That Was Close! Reward Reporting Of Cybersecurity “Near Misses”, Jonathan Bair, Steven M. Bellovin, Andrew Manley, Blake Reid, Adam Shostak

Publications

Building, deploying, and maintaining systems with sufficient cybersecurity is challenging. Faster improvement would be valuable to society as a whole. Are we doing as much as we can to improve? We examine robust and long-standing systems for learning from near misses in aviation, and propose the creation of a Cyber Safety Reporting System (CSRS).

To support this argument, we examine the liability concerns which inhibit learning, including both civil and regulatory liability. We look to the way in which cybersecurity engineering and science is done today, and propose that a small amount of ‘policy entrepreneurship’ could have substantial positive impact. …

Beyond Brooke Group: Bringing Reality To The Law Of Predatory Pricing, C. Scott Hemphill, Philip J. Weiser

Publications

This Feature offers a roadmap for bringing and deciding predatory pricing cases under the Supreme Court’s restrictive Brooke Group decision. Brooke Group requires a plaintiff to show that the defendant set a price below cost and had a sufficient likelihood of recouping its investment in predation. This framework, which was adopted without any contested presentation of its merits, has endured despite its flaws. Beyond this framework, the Court opined in dicta that predation is implausible.

We identify points of flexibility within the Court’s framework that permit an empirically grounded evaluation of the predation claim. Under the price-cost test, a plaintiff …

Tracking Colorado Legislation, Robert Linz

Publications

No abstract provided.

Arguing With The Building Inspector About Gender-Neutral Bathrooms, Jennifer S. Hendricks

Publications

Conventional interpretations of building codes are among the greatest barriers to building the gender-neutral bathrooms of the future. Focusing on the example of schools, this Essay argues for a reinterpretation of the International Building Code in light of its policy goals: safe, private, and equitable access to public bathrooms. Under this reinterpretation, the Code allows all public bathrooms to be gender-neutral.

The Consensus Myth In Criminal Justice Reform, Benjamin Levin

Publications

It has become popular to identify a “consensus” on criminal justice reform, but how deep is that consensus, actually? This Article argues that the purported consensus is much more limited than it initially appears. Despite shared reformist vocabulary, the consensus rests on distinct critiques that identify different flaws and justify distinct policy solutions. The underlying disagreements transcend traditional left/right political divides and speak to deeper disputes about the state and the role of criminal law in society.

The Article maps two prevailing, but fundamentally distinct, critiques of criminal law: (1) the quantitative approach (what I call the “over” frame); and …

Thinking Fast And Slow About The Concept Of Materiality, Mark J. Loewenstein

Publications

Determining whether, for securities law purposes, a misrepresentation or omission is material raises interesting questions. The Court of Appeals in SEC v. Texas Gulf Sulphur Co. provided some guidance on materiality, and the U.S. Supreme Court has weighed in several times in the past 50 years. This article first discusses what Texas Gulf Sulphur contributed to the doctrine of materiality, then briefly considers other dimensions of the doctrine, and finally moves to its thesis: The doctrine of materiality should take into account important psychological insights and heuristics that may affect the way that a fact finder decides whether a misrepresentation …

The Disruptive Neuroscience Of Judicial Choice, Anna Spain Bradley

Publications

Scholars of judicial behavior overwhelmingly substantiate the historical presumption that most judges act impartially and independent most of the time. The reality of human behavior, however, says otherwise. Drawing upon untapped evidence from neuroscience, this Article provides a comprehensive evaluation of how bias, emotion, and empathy—all central to human decision-making—are inevitable in judicial choice. The Article offers three novel neuroscientific insights that explain why this inevitability is so. First, because human cognition associated with decision-making involves multiple, and often intersecting, neural regions and circuits, logic and reason are not separate from bias and emotion in the brain. Second, bias, emotion, …

Sanctuary Networks And Integrative Enforcement, Ming Hsu Chen

Publications

My intended focus is on the widespread response--in cities, churches, campuses, and corporations that together comprise "sanctuary networks"--to the Trump Administration's Executive Order 13768 Enhancing Public Safety in the Interior of the United States as an instance of the changing relationship between federal, local, and private organizations in the regulation of immigration. After briefly covering the legal background of the Trump Interior E.O., the focus of the Article shifts to the institutional dynamics arising in communities. These institutional dynamics exemplify the beginnings of a reimagined immigration enforcement policy with a more integrative flavor.

Market Pbl: A Cross-Curricular Exploration Of Technological Innovation In Pre-Modern Civilizations, Elizabeth Muire, M. Melendy Jacobie, Kay Newsome, Lisa Stuckey, Blake Keeling

Understanding by Design: Complete Collection

This project-based learning unit incorporates knowledge from history, English, math and science courses. Students explore how geography and available resources, coupled with technological advancements, shape a civilization’s industry and therefore the quality of life of the inhabitants. Students design a product that could be made from the natural resources of their civilization and attempt to sell their product in a simulated market.

Generating Adversarial Attacks For Sparse Neural Networks, Jack H. Chen, Walt Woods

Maseeh Summer Undergraduate Research Experience

Neural networks provide state-of-the-art accuracy for image classification tasks. However traditional networks are highly susceptible to imperceivable perturbations to their inputs known as adversarial attacks that drastically change the resulting output. The magnitude of these perturbations can be measured as Mean Squared Error (MSE). We use genetic algorithms to produce black-box adversarial attacks and examine MSE on state-of-the-art networks. This method generates an attack that converts 90% confidence on a correct class to 50% confidence of a targeted, incorrect class after 2000 epochs. We will generate and examine attacks and their MSE against several sparse neural networks. We theorize that …

Early Emerging Pathogen Detection, Mackenzie Wangenstein

Maseeh Summer Undergraduate Research Experience

A supervised learning technique was employed to identify emerging pathogen species. Portland State University has partnered with the University of New Mexico to take encodings of unknown pathogen molecular structures to determine emerging species.

Celebrating Mundane Conflict, Deborah J. Cantrell

Publications

This Article interrogates the dominant conception of conflict and challenges the narrative of conflict as hard, difficult and painful to engage. The Article reveals two primary framing errors that cause one to misperceive how ubiquitous and ordinary is conflict. The first error is to misperceive conflict as categorical — something either is a conflict or it is not. People make that error as a way of trying to avoid conflict. People falsely hope that there might be a category of “not conflict,” like disagreements, that will be easier to navigate. The second error is to misperceive the world and individuals …