Digital Commons Network^™

September 11, 2018 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Carbon Nanotube Anchor For Mass Spectrometer, Rudiger Schlaf, Joshua Schumacher

USF Patents

This invention enables a sensitivity enhancement in the detection of molecular compounds. A mass spectrometry analyte support with nanotube anchors are used to concentrate MALDI samples prepared with water-insoluble matrix compounds on the anchor spot. A matrix solution mixed with analyte molecules is spotted onto a specialized MALDI plate using carbon nanotubes to selectively nucleate the analyte. The spot diameter of the target is usually several orders of magnitude larger than traditional supports, and led to lateral concentration for non-aqueous based matrices and produced a final dried matrix/analyte spot that was approximately the diameter of the laser spot at the …

Ecology And Population Dynamics Of Salmonids In The Columbia River: Response Of Fishes To Anthropogenic Change In A Large Riverscape, Timothy Sean Elder

Dissertations and Theses

Freshwater ecosystems and the species that reside therein are disproportionately imperiled compared to terrestrial systems. Over the past 150 years, the Columbia River basin in the western United States has gone from one of the most productive and abundant salmon watersheds in the world, to having just a small fraction of its former salmon abundance. The cause of declines in salmon productivity and abundance are related to overlapping and confounding stressors including changes in large-scale climatic patterns and anthropogenic alterations within and adjacent to the Columbia River. Four main anthropogenic stressors have been identified as the leading causes of salmonid …

In Vivo Brainstem Imaging In Alzheimer’S Disease: Potential For Biomarker Development, David J. Braun, Linda J. Van Eldik

Neuroscience Faculty Publications

The dearth of effective treatments for Alzheimer’s disease (AD) is one of the largest public health issues worldwide, costing hundreds of billions of dollars per year. From a therapeutic standpoint, research efforts to date have met with strikingly little clinical success. One major issue is that trials begin after substantial pathological change has occurred, and it is increasingly clear that the most effective treatment regimens will need to be administered earlier in the disease process. In order to identify individuals within the long preclinical phase of AD who are likely to progress to dementia, improvements are required in biomarker development. …

Unraveling The Stereodynamics Of Cold Controlled Hd−H2 Collisions, James F. E. Croft, Naduvalath Balakrishnan, Meng Huang, Hua Guo

Chemistry and Biochemistry Faculty Research

Measuring inelastic rates with partial-wave resolution requires temperatures close to a Kelvin or below, even for the lightest molecule. In a recent experiment, Perreault, Mukherjee, and Zare [Nat. Chem. 10, 561 (2018).] studied collisional relaxation of excited HD molecules in the v=1, j=2 state by para- and ortho-H2 at a temperature of about 1 K, extracting the angular distribution of scattered HD in the v=1, j=0 state. By state preparation of the HD molecules, control of the angular distribution of scattered HD was demonstrated. Here, we report a first-principles simulation of that experiment which enables us to attribute the main …

A Summer To Remember, Eric F. Spina

President's Blog: From the Heart

It's not hard to spot University of Dayton students, even if their T-shirts don’t sport our ever-present logo. They carry their passion like a calling card.

Effects Of Protein Supplementation On Performance And Recovery In Resistance And Endurance Training, Harry P. Cintineo, Michelle A. Arent, Jose Antonio, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak

Faculty Publications

There is robust evidence which shows that consuming protein pre- and/or post-workout induces a significant rise in muscle protein synthesis. It should be noted, however, that total daily caloric and protein intake over the long term play the most crucial dietary roles in facilitating adaptations to exercise. However, once these factors are accounted for, it appears that peri-exercise protein intake, particularly in the post-training period, plays a potentially useful role in terms of optimizing physical performance and positively influencing the subsequent recovery processes for both resistance training and endurance exercise. Factors that affect the utility of pre- or post-workout feeding …

Glycosaminoglycan-Protein Interactions By Nuclear Magnetic Resonance (Nmr) Spectroscopy, Vitor Pomin, Xu Wang

Faculty and Student Publications (Open Access)

Nuclear magnetic resonance (NMR) spectroscopy is one of the most utilized and informative analytical techniques for investigating glycosaminoglycan (GAG)-protein complexes. NMR methods that are commonly applied to GAG-protein systems include chemical shift perturbation, saturation transfer difference, and transferred nuclear Overhauser effect. Although these NMR methods have revealed valuable insight into the protein-GAG complexes, elucidating high-resolution structural and dynamic information of these often transient interactions remains challenging. In addition, preparation of structurally homogeneous and isotopically enriched GAG ligands for structural investigations continues to be laborious. As a result, understanding of the structure-activity relationship of GAGs is still primitive. To overcome these …

Can Placental Corticotropin-Releasing Hormone Inform Timing Of Antenatal Corticosteroid Administration?, Danielle A. Swales, Leah A. Grande, Deborah A. Wing, Michelle Edelmann, Laura M. Glynn, Curt A. Sandman, Roger Smith, Maria Bowman, Elysia Poggi Davis

Psychology Faculty Articles and Research

Context

Antenatal corticosteroids commonly are administered to pregnant women at risk of delivering between 23 and 34 gestational weeks, providing crucial benefits to fetal lung maturation and reducing risk of neonatal morbidity and mortality. Corticosteroids are maximally efficacious for lung maturation when administered within 2 to 7 days of delivery. Accurately identifying the timing of preterm delivery is thus critical to ensure that antenatal corticosteroids are administered within a week of delivery and to avoid unnecessary administration to women who will deliver at term. A plausible biomarker for predicting time of delivery is placental corticotropin-releasing hormone (pCRH). Objective

The current …

Tiny Earth Network Builds Student Researchers In Antibiotics, Rachel Mccarthy

News and Events (Discontinued Series)

No abstract provided.

Student Internships Open A World Of Opportunities, Rachel Mccarthy

News and Events (Discontinued Series)

No abstract provided.

The Prospector, September 11, 2018, Utep Student Publications

The Prospector

Headline: UTEP Receives Grant to Combat Sexual Violence

Integrating Standardized Whole Genome Sequence Analysis With A Global Mycobacterium Tuberculosis Antibiotic Resistance Knowledgebase, Rumina Hasan, Matthew Ezewudo, Amanda Borens, Álvaro Chiner-Oms, Paolo Miotto, Leonid Chindelevitch, Angela M. Starks, Debra Hanna, Richard Liwsk, Matteo Zignol

Department of Pathology and Laboratory Medicine

Drug-resistant tuberculosis poses a persistent public health threat. The ReSeqTB platform is a collaborative, curated knowledgebase, designed to standardize and aggregate global Mycobacterium tuberculosis complex (MTBC) variant data from whole genome sequencing (WGS) with phenotypic drug susceptibility testing (DST) and clinical data. We developed a unified analysis variant pipeline (UVP) ( https://github.com/CPTR-ReSeqTB/UVP ) to identify variants and assign lineage from MTBC sequence data. Stringent thresholds and quality control measures were incorporated in this open source tool. The pipeline was validated using a well-characterized dataset of 90 diverse MTBC isolates with conventional DST and DNA Sanger sequencing data. The UVP exhibited …

Inside America: An Analysis Of The Capitalistic Domination Of Mexican Farmworkers, Shamaila Ali Taj

Culture, Society, and Praxis

The following essay is a collection of the how the American ideal affects me and Mexican immigrant farmworkers. I analyze capitalism’s role in the creation and hindrance of the agricultural labor community. Also I discuss various historical events and individuals that have been a part of the “Americanization” process and its effects. I present the health exposures and the Federal Laws established in respect to the safety of the farmworkers. I also discuss my involvement in and purpose of The Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS). And lastly, I analyze how Critical Race Theory …

Why Professors Hate Their Jobs: A Critique Of The Pedagogy Of Academic Disengagement, Jim Parsons, William Frick

Culture, Society, and Praxis

This article explores reasons why many academics “hate” their jobs. The authors explore the current state of the academy and focus upon its values, culture, and possibilities. They contend that the academy fosters a pedagogy (defined broadly) of disengagement, and ask: Why might these feelings exist? What possibilities for edification exist? How might we move towards these possibilities? Both pragmatic and philosophical are explored and the authors make seven suggestions that might help more fruitfully engage academics in their work. These suggestions include changes to our language, values and worldviews, norms, and the way we create and use artifacts.

Do I Pass?, Ana Yesica Moran

Culture, Society, and Praxis

Ana Moran explores de intricacies of cultural identity and gender while living in a modern time, where the constant is change. This vibrant piece will take the reader to consider his/her own commitment to living in an open society. Do you pass the test?

Buffalo Field Campaign V. Zinke, Hallee C. Kansman

Public Land & Resources Law Review

Despite years of litigation and legislation, the protection status of bison in and around Yellowstone National Park remains unsettled. Buffalo Field Campaign, a non-profit group, has spent decades spearheading the fight to list the species as either endangered or threatened under the Endangered Species Act. Buffalo Field Campaign v. Zinke tests the scope of agency directives and the strictness of the statutory language which guides agency actions.

Effects Of Commercial Diets On Growth Performances Of Juvenile Hybrid Grouper (Epinephelus Lanceolatus ♂ X E. Fuscoguttatus ♀) Reared Under Intensive Culture Conditions, Piyawut Mitrananda

Open Access Theses

Feed performance of hybrid grouper (Epinephelus lanceolatus ♂ x E. fuscoguttatus ♀) at 27.76±0.78 grams were evaluated. Fish were fed one control diet and three commercial diets for a duration of 42 days with 14-day sampling intervals. Experiment was performed in triplicates with 240 fish per treatment. Fish were stocked in 400-liter flow through tank with 2000% exchange of unfiltered seawater. Control treatment received previously frozen bait fish, Decapterus russelli. The three commercial diets have varying proximate compositions and price points and were obtained from three commercial fish feed producers. CD1 diet was imported from Japan at $2.7/kg with 50.8% …

Neighbourhood Deprivation And Lung Cancer Risk: A Nested Case–Control Study In The Usa, Maureen Sanderson, Melinda C. Aldrich, Robert S. Levine, Barbara J. Kilbourne, Qiuyin Cai, William J. Blot

Sociology Faculty Research

Objectives To examine the association between neighbourhood deprivation and lung cancer risk.

Design Nested case–control study.

Setting Southern Community Cohort Study of persons residing in 12 states in the southeastern USA.

Participants 1334 cases of lung cancer and 5315 controls.

Primary outcome measure Risk of lung cancer.

Results After adjustment for smoking status and other confounders, and additional adjustment for individual-level measures of socioeconomic status (SES), there was no monotonic increase in risk with worsening deprivation score overall or within sex and race groups. There was an increase among current and shorter term former smokers (p=0.04) but not among never …

Potential Roles Of Smell And Taste In The Orientation Behaviour Of Coral‐Reef Fish Larvae: Insights From Morphology, Yinan Hu, John E. Majoris, Peter M. Buston, Jacqueline F. Webb

Biological Sciences Faculty Publications

An ontogenetic analysis of the olfactory organ and the number and distribution of internal taste buds was carried out in two neon gobies (Elacatinus lori and Elacatinus colini) with the goal of revealing morphological trends that might inform an understanding of the roles of olfaction and taste in larval orientation behaviour. The pattern of development of the olfactory organ is unremarkable and enclosure of the olfactory epithelium occurs concurrently with metamorphosis and settlement in both species. Like other gobies, juvenile and adult E. lori and E. colini lack complex olfactory lamellae, and lack the accessory nasal sacs present …

Ability Of Ir And Nmr Spectral Data To Distinguish Between A Tetrel Bond And A Hydrogen Bond, Steve Scheiner

Chemistry and Biochemistry Faculty Publications

The placement of a nucleophile X along the R-CH3 axis of a methyl group can be described as either a trifurcated H-bond or as a tetrel bond between C and X. Quantum calculation of the vibrational and NMR spectral features of a number of systems are used to provide a framework by which to distinguish between the presence of a tetrel or H-bond. Both cationic and neutral methyl-containing Lewis acids (SMe3+, NMe4+, SMe2) are paired with both neutral and anionic Lewis bases (NH3, OH2, OCHNH2, OCH3-, OH-, HCOO-). As the base is moved away from the R-CH3 axis of the …

Grand Valley Forum, Volume 043, Number 02, September 10, 2018, Grand Valley State University

2018-2019, Volume 43

Grand Valley Forum is Grand Valley State's faculty and staff newsletter, published from 1976 to the present.

Faculty Senate Agenda, September 10, 2018, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• Nominating Committee Code
• Additional Events During the Year in which a Tenure Decision is to be Made (Code 405.11.4)

Vis Named Vice President Of International Phycological Society, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Ohio Student Farm Tomatoes Harvested For Nelsonville Food Cupboard, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

University Of Northern Iowa Faculty Senate Meeting Agenda, September 10, 2018, University Of Northern Iowa. Faculty Senate.

Documents - Faculty Senate

Meeting agenda from the Faculty Senate of the University of Northern Iowa.

Edwardsiella Ictaluri Type Iii Secretion System (T3ss) Effector Esen Is A Phosphothreonine Lyase That Inactivates Erk1/2, Lidiya P. Dubytska, Ronald L. Thune

Faculty Publications

© The authors 2018. EseN is a type III secretion system (T3SS) effector that is encoded on the Edwardsiella ictaluri chromosome and is homologous to a family of T3SS effector proteins with phosphothreonine lyase (PTL) activity, including OspF from Shigella and SpvC from Salmonella. A yeast-2-hybrid system was used to identify the major vault protein (MVP) as a specific host-cell binding partner for EseN, and the proximity ligation assay (PLA) confirmed the interaction. Similar to other pathogens, E. ictaluri invasion activates extracellular signal-regulated kinases 1 and 2 (ERK1/2) early in the infection, which are subsequently inactivated by EseN. Structurally, EseN …

University Of Northern Iowa Faculty Senate Meeting Minutes, September 10, 2018, University Of Northern Iowa. Faculty Senate.

Documents - Faculty Senate

Meeting minutes from the Faculty Senate of the University of Northern Iowa.

Crow's Nest, September 10, 2018, Crow's Nest Staff

Crow's Nest

The September 10, 2018, issue of the Crow's Nest.

Glutathione De Novo Synthesis But Not Recycling Process Coordinates With Glutamine Catabolism To Control Redox Homeostasis And Directs Murine T Cell Differentiation, Gaojian Lian, J. N. Rashida Gnanaprakasam, Tingting Wang, Ruohan Wu, Xuyong Chen, Lingling Liu, Yuqing Shen, Mao Yang, Jun Yang, Ying Chen, Vasilis Vasiliou, Teresa A. Cassel, Douglas R. Green, Yusen Liu, Teresa W. -M. Fan, Ruoning Wang

Toxicology and Cancer Biology Faculty Publications

Upon antigen stimulation, T lymphocytes undergo dramatic changes in metabolism to fulfill the bioenergetic, biosynthetic and redox demands of proliferation and differentiation. Glutathione (GSH) plays an essential role in controlling redox balance and cell fate. While GSH can be recycled from Glutathione disulfide (GSSG), the inhibition of this recycling pathway does not impact GSH content and murine T cell fate. By contrast, the inhibition of the de novo synthesis of GSH, by deleting either the catalytic (Gclc) or the modifier (Gclm) subunit of glutamate–cysteine ligase (Gcl), dampens intracellular GSH, increases ROS, and impact T cell differentiation. Moreover, the inhibition of …