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2018

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Development And Evaluation Of An Eeg-Based Symbol-Digit Substitution Task, Christopher Beckett, Dr. Bruce Brown Sep 2018

Development And Evaluation Of An Eeg-Based Symbol-Digit Substitution Task, Christopher Beckett, Dr. Bruce Brown

Journal of Undergraduate Research

The event-related potential (ERP) method has led to major advances in the experimental exploration of the neurological correlates of human cognition (Luck, 2005). The usual process is to take EEG (electroencephalographic) recordings during a cognitive task. The recording is timelocked to a stimulus so that multiple trials can be averaged to amplify the signal of the resulting cognitive process. In past research studies, faculty and students in our Quantitative EEG Lab (qEEG) have discovered a way to isolate individual cognitive “bands” within a set of ERP waves. These cognitive bands have diagnostic utility. They can be used to identify personal …


Looking On The Bright Side Of Livestock Emotions—The Potential Of Their Transmission To Promote Positive Welfare, Luigi Baciadonna, Sandra Duepjan, Elodie Briefer, Mónica Padilla De La Torre, Christian Nawroth Sep 2018

Looking On The Bright Side Of Livestock Emotions—The Potential Of Their Transmission To Promote Positive Welfare, Luigi Baciadonna, Sandra Duepjan, Elodie Briefer, Mónica Padilla De La Torre, Christian Nawroth

Emotion Collection

Emotions can be defined as an individual’s affective reaction to an external and/or internal event that, in turn, generates a simultaneous cascade of behavioral, physiological, and cognitive changes. Those changes that can be perceived by conspecifics have the potential to also affect other’s emotional states, a process labeled as “emotional contagion.” Especially in the case of gregarious species, such as livestock, emotional contagion can have an impact on the whole group by, for instance, improving group coordination and strengthening social bonds. We noticed that the current trend of research on emotions in livestock, i.e., investigating affective states as a tool …


Cryptic Diversity In The North American Dromochorus Tiger Beetles (Coleoptera: Carabidae: Cicindelinae): A Congruence-Based Method For Species Discovery, Daniel P. Duran, David P. Herrman, Stephen J. Roman, Rodger A. Gwiazdowski, Jennifer A. Drummond, Glen R. Hood, Scott P. Egan Sep 2018

Cryptic Diversity In The North American Dromochorus Tiger Beetles (Coleoptera: Carabidae: Cicindelinae): A Congruence-Based Method For Species Discovery, Daniel P. Duran, David P. Herrman, Stephen J. Roman, Rodger A. Gwiazdowski, Jennifer A. Drummond, Glen R. Hood, Scott P. Egan

School of Earth & Environment Departmental Research

A fundamental problem in biodiversity science is determining the number of species in any taxon, and there is a growing awareness that cryptic diversity contributes to this problem – even in well-studied groups. Discovering cryptic species requires several lines of evidence to elucidate congruent patterns across data-types, and distinguish unrecognized species. Tiger beetles are among the most well-studied insect groups; yet few new North American species have been described since the mid-20th century, suggesting that that the number of morphologically distinct species is reaching an asymptote. We explore the possibility that more species exist in the fauna as cryptic species, …


Different Ommochrome Pigment Mixtures Enable Sexually Dimorphic Batesian Mimicry In Disjunct Populations Of The Common Palmfly Butterfly, Elymnias Hypermnestra, Silvio Panettieri, Erisa Gjinaj, George John, David J. Lohman Sep 2018

Different Ommochrome Pigment Mixtures Enable Sexually Dimorphic Batesian Mimicry In Disjunct Populations Of The Common Palmfly Butterfly, Elymnias Hypermnestra, Silvio Panettieri, Erisa Gjinaj, George John, David J. Lohman

Publications and Research

With varied, brightly patterned wings, butterflies have been the focus of much work on the evolution and development of phenotypic novelty. However, the chemical structures of wing pigments from few butterfly species have been identified. We characterized the orange wing pigments of female Elymnias hypermnestra butterflies (Lepidoptera: Nymphalidae: Satyrinae) from two Southeast Asian populations. This species is a sexually dimorphic Batesian mimic of several model species. Females are polymorphic: in some populations, females are dark, resemble conspecific males, and mimic Euploea spp. In other populations, females differ from males and mimic orange Danaus spp. Using LC-MS/MS, we identified nine ommochrome …


Faculty Honored At 2018 Argus Awards Ceremony, Brit Blalock Sep 2018

Faculty Honored At 2018 Argus Awards Ceremony, Brit Blalock

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No abstract provided.


Students And Sexual Orientation: A Study Of Students And Their Development At Higher Educational Institutions, Diamond Bolden Sep 2018

Students And Sexual Orientation: A Study Of Students And Their Development At Higher Educational Institutions, Diamond Bolden

Theses and Dissertations

The primary purpose of this study was to explore and assess student sexual identity development on college students, in particular sophomore, junior, and senior students at Rowan University, Glassboro, NJ in the spring 2018 semester. The study also investigated the impact of demographic factors and other variables such as gender, ethnicity, and social life. The instrument used to assess students' anxiety levels and attitudes toward sexual orientation was adapted from two surveys used in previous studies, one about Lesbian, Gay, Bisexual, Transgender, and Queer (LGBTQ) and gender development, as well as student anxiety. It was assessed with survey questions created …


Emerging Themes In Food Security: Environmental Justice, Extended Families And The Multiple Roles Of Grandmothers., Ethel Alderete, Lauren Sonderegger, Eliseo J Pérez-Stable Sep 2018

Emerging Themes In Food Security: Environmental Justice, Extended Families And The Multiple Roles Of Grandmothers., Ethel Alderete, Lauren Sonderegger, Eliseo J Pérez-Stable

Articles, Abstracts, and Reports

BACKGROUND: Pre- and perinatal nutritional status defines the development of adult metabolism and energy balance in humans. Young children in poor households are disproportionately more vulnerable to food insecurity given the cumulative impact of chronic stress on susceptibility to chronic diseases as an adult. Qualitative studies focusing on the experience of food insecurity in Latin America are scarce. In Argentina, although socioeconomic indicators improved in the aftermath of the 2001ecomomic crisis, the disadvantaged provinces in the north continue to bear the burden of historical inequities. The study was conducted among Primary Health Care patients in the city of San Salvador …


Myocyte [Na+]I Dysregulation In Heart Failure And Diabetic Cardiomyopathy, Sanda Despa Sep 2018

Myocyte [Na+]I Dysregulation In Heart Failure And Diabetic Cardiomyopathy, Sanda Despa

Pharmacology and Nutritional Sciences Faculty Publications

By controlling the function of various sarcolemmal and mitochondrial ion transporters, intracellular Na+ concentration ([Na+]i) regulates Ca2+ cycling, electrical activity, the matching of energy supply and demand, and oxidative stress in cardiac myocytes. Thus, maintenance of myocyte Na+ homeostasis is vital for preserving the electrical and contractile activity of the heart. [Na+]i is set by the balance between the passive Na+ entry through numerous pathways and the pumping of Na+ out of the cell by the Na+/K+-ATPase. This equilibrium is perturbed in heart failure, …


Authenticating Smart Device Users With Behavioral Biometrics, Yanyan Li Sep 2018

Authenticating Smart Device Users With Behavioral Biometrics, Yanyan Li

Theses and Dissertations

Designed as personal smart assistant, smartphones and smartwatches have dramatically changed people's lives in every aspect from social network communication, navigation to both online and offline shopping. A large amount of personal data such as messages, emails and payment information is stored in such a device. Such data, if lost, can lead to privacy leakage and financial loss. Therefore, protecting such devices from unauthorized access is crucial. Despite the existence of personal identification numbers (PIN) and unlock patterns for user authentication, they have well known drawbacks. Although physiological biometrics such as fingerprints and facial recognition has become popular, they suffer …


Isolation Of Rna From A Mixture And Its Detection By Utilizing A Microgel-Based Optical Device, Molla R. Islam, Shakiba Azimi, Faranak Teimoory, Glen Loppnow, Michael J. Serpe Sep 2018

Isolation Of Rna From A Mixture And Its Detection By Utilizing A Microgel-Based Optical Device, Molla R. Islam, Shakiba Azimi, Faranak Teimoory, Glen Loppnow, Michael J. Serpe

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

In this investigation, we show that RNA can be separated from a solution containing DNA and RNA and the isolated RNA can be detected using poly (N-isopropylacrylamide-co-N-(3-aminopropyl) methacrylamide hydrochloride) microgel-based optical devices (etalons). The isolation of RNA was accomplished by using hairpin-functionalized magnetic beads (MMPDNA) and differential melting, based on the fact that the DNA–RNA hybrid duplex is stronger (i.e., high melting temperature) than the DNA–DNA duplex (i.e., low melting temperature). By performing concurrent etalon sensing and fluorescent studies, we found that the MMPDNA combined with differential melting was capable of selectively separating RNA from DNA. This selective separation and …


Librarians’ Roles In Establishing A Multidisciplinary Research Institute, Elizabeth Christian, Kathryn Balek, Sandy Hudock, Rhonda Gonzales Sep 2018

Librarians’ Roles In Establishing A Multidisciplinary Research Institute, Elizabeth Christian, Kathryn Balek, Sandy Hudock, Rhonda Gonzales

Collaborative Librarianship

This article describes how four librarians contributed to the founding and first-year activities of a multidisciplinary research institute at a regional comprehensive university. The Institute of Cannabis Research (ICR) is the first multidisciplinary research institute on cannabis, an emerging and often controversial field. As faculty representatives on the institute’s steering committee and working groups, librarians were able to leverage interdisciplinary expertise to assist in organizing and disseminating cannabis research. Examples of the reciprocal benefit to both the institution and the library are shared.


Isolation Of Cerebral Capillaries From Fresh Human Brain Tissue, Anika M. S. Hartz, Julia A. Schulz, Brent S. Sokola, Stephanie E. Edelmann, Andrew N. Shen, Ralf G. Rempe, Yu Zhong, Nader El Seblani, Bjoern Bauer Sep 2018

Isolation Of Cerebral Capillaries From Fresh Human Brain Tissue, Anika M. S. Hartz, Julia A. Schulz, Brent S. Sokola, Stephanie E. Edelmann, Andrew N. Shen, Ralf G. Rempe, Yu Zhong, Nader El Seblani, Bjoern Bauer

Sanders-Brown Center on Aging Faculty Publications

Understanding blood-brain barrier function under physiological and pathophysiological conditions is critical for the development of new therapeutic strategies that hold the promise to enhance brain drug delivery, improve brain protection, and treat brain disorders. However, studying the human blood-brain barrier function is challenging. Thus, there is a critical need for appropriate models. In this regard, brain capillaries isolated from human brain tissue represent a unique tool to study barrier function as close to the human in vivo situation as possible. Here, we describe an optimized protocol to isolate capillaries from human brain tissue at a high yield and with consistent …


Differential Responses Of Met Activations To Met Kinase Inhibitor And Neutralizing Antibody, Jianqun Kou, Phillip R. Musich, Ben Staal, Liang Kang, Yuan Qin, Zhi Q. Yao, Boheng Zhang, Weizhong Wu, Angela Tam, Alan Huang, Huai Xiang Hao, George F. Vande Woude, Qian Xie Sep 2018

Differential Responses Of Met Activations To Met Kinase Inhibitor And Neutralizing Antibody, Jianqun Kou, Phillip R. Musich, Ben Staal, Liang Kang, Yuan Qin, Zhi Q. Yao, Boheng Zhang, Weizhong Wu, Angela Tam, Alan Huang, Huai Xiang Hao, George F. Vande Woude, Qian Xie

ETSU Faculty Works

Background: Aberrant MET tyrosine kinase signaling is known to cause cancer initiation and progression. While MET inhibitors are in clinical trials against several cancer types, the clinical efficacies are controversial and the molecular mechanisms toward sensitivity remain elusive. Methods: With the goal to investigate the molecular basis of MET amplification (MET amp ) and hepatocyte growth factor (HGF) autocrine-driven tumors in response to MET tyrosine kinase inhibitors (TKI) and neutralizing antibodies, we compared cancer cells harboring MET amp (MKN45 and MHCCH97H) or HGF-autocrine (JHH5 and U87) for their sensitivity and downstream biological responses to a MET-TKI (INC280) and an anti-MET …


Aquatic Ecosystems In A Shifting Indiana Climate: A Report From The Indiana Climate Change Impacts Assessment, Tomas Höök, Carolyn Foley, Paris Collingsworth, Leslie Dorworth, Brant Fisher, Jason Hoverman Dr., Elizabeth Larue, Mark Pyron, Jennifer Tank, Melissa Widhalm, Jeffrey Dukes Sep 2018

Aquatic Ecosystems In A Shifting Indiana Climate: A Report From The Indiana Climate Change Impacts Assessment, Tomas Höök, Carolyn Foley, Paris Collingsworth, Leslie Dorworth, Brant Fisher, Jason Hoverman Dr., Elizabeth Larue, Mark Pyron, Jennifer Tank, Melissa Widhalm, Jeffrey Dukes

Aquatic Ecosystems Reports

Indiana is home to many types of aquatic ecosystems, including lakes, rivers, streams, wetlands and temporary (ephemeral) pools, which provide habitats for a wide range of plants and animals. These ecosystems will experience changes in water quantity, water temperature, ice cover, water clarity and oxygen content as the state’s temperature and rainfall patterns shift. The plants and animals living in these aquatic ecosystems will undergo changes that will vary based on the species and the specific places they inhabit.

It is challenging to know precisely how organisms will respond to changes in climate. Effects on one species create a difficult-to-predict …


Comparative Demography Elucidates The Longevity Of Parasitic And Symbiotic Relationships, Luke B.B. Hecht, Peter C. Thompson, Benjamin M. Rosenthal Sep 2018

Comparative Demography Elucidates The Longevity Of Parasitic And Symbiotic Relationships, Luke B.B. Hecht, Peter C. Thompson, Benjamin M. Rosenthal

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Parasitic and symbiotic relationships govern vast nutrient and energy flows, yet controversy surrounds their longevity. Enduring relationships may engender parallel phylogenies among hosts and parasites, but so may ephemeral relationships when parasites colonize related hosts. An understanding of whether symbiont and host populations have grown and contracted in concert would be useful when considering the temporal durability of these relationships. Here, we devised methods to compare demographic histories derived from genomic data. We compared the historical growth of the agent of severe human malaria, Plasmodium falciparum, and its mosquito vector, Anopheles gambiae, to human and primate histories, thereby discerning long-term …


Cover Crops May Cause Winter Warming In Snow-Covered Regions, Danica L. Lombardozzi, Gordon B. Bonan Sep 2018

Cover Crops May Cause Winter Warming In Snow-Covered Regions, Danica L. Lombardozzi, Gordon B. Bonan

Faculty Publications

Cover crops, grown between cash crops when soil is fallow, are a management strategy that may help mitigate climate change. The biogeochemical effects of cover crops are well documented, as they provide numerous localized benefits to farmers. We test potential biogeophysical climate impacts of idealized cover crop scenarios by assuming that cover crops are planted offseason in all crop regions throughout North America. Our results suggest that planting cover crops increases wintertime temperature up to 3 °C in central North America by decreasing albedo in regions with variable snowpack. Cover crops with higher leaf area indices increase temperature more by …


A Case Study Of Instructional Leadership, Remediation, And Student Success In Algebra I In Four Public High Schools, Frankie Horton James Sep 2018

A Case Study Of Instructional Leadership, Remediation, And Student Success In Algebra I In Four Public High Schools, Frankie Horton James

Theses and Dissertations

The purpose of this qualitative case study was to examine leadership styles and practices of principals to see how they contributed to math achievement and efficiency with remediation programs on student success in public education in a southern state. The case study focused specifically on leadership styles and philosophy of four strong and independent high school principals who used remediation to promote test scores on the Algebra I EOC exam for students. Data was collected through in-depth interviews, artifacts and published literature with the principals of one southern school district. The conceptual framework for the study was based on instructional …


Radiolytic H2 Production In Martian Environments, Mary Dzaugis, Arthur J. Spivack, Steven D’Hondt Sep 2018

Radiolytic H2 Production In Martian Environments, Mary Dzaugis, Arthur J. Spivack, Steven D’Hondt

Graduate School of Oceanography Faculty Publications

Hydrogen, produced by water radiolysis, has been suggested to support microbial communities on Mars. We quantitatively assess the potential magnitude of radiolytic H2 production in wet martian environments (the ancient surface and the present subsurface) based on the radionuclide compositions of (1) eight proposed Mars 2020 landing sites, and (2) three sites that individually yield the highest or lowest calculated radiolytic H2 production rates on Mars. For the proposed landing sites, calculated H2 production rates vary by a factor of ∼1.6, while the three comparison sites differ by a factor of ∼6. Rates in wet martian sediment and microfractured rock …


Dietary Docosahexaenoic Acid Prevents Silica-Induced Development Of Pulmonary Ectopic Germinal Centers And Glomerulonephritis In The Lupus-Prone Nzbwf1 Mouse, Melissa A. Bates, Peyman Akbari, Kristen N. Gilley, James G. Wagner, Ning Li, Anna K. Kopec, Kathryn A. Wierenga, Daven Jackson-Humbles, Christina Brandenberger, Andrij Holian, Abby D. Benninghoff, Jack R. Harkema, James J. Pestka Sep 2018

Dietary Docosahexaenoic Acid Prevents Silica-Induced Development Of Pulmonary Ectopic Germinal Centers And Glomerulonephritis In The Lupus-Prone Nzbwf1 Mouse, Melissa A. Bates, Peyman Akbari, Kristen N. Gilley, James G. Wagner, Ning Li, Anna K. Kopec, Kathryn A. Wierenga, Daven Jackson-Humbles, Christina Brandenberger, Andrij Holian, Abby D. Benninghoff, Jack R. Harkema, James J. Pestka

Animal, Dairy, and Veterinary Science Faculty Publications

Ectopic lymphoid structures (ELS) consist of B-cell and T-cell aggregates that are initiated de novo in inflamed tissues outside of secondary lymphoid organs. When organized within follicular dendritic cell (FDC) networks, ELS contain functional germinal centers that can yield autoantibody-secreting plasma cells and promote autoimmune disease. Intranasal instillation of lupus-prone mice with crystalline silica (cSiO2), a respirable particle linked to human lupus, triggers ELS formation in the lung, systemic autoantibodies, and early onset of glomerulonephritis. Here we tested the hypothesis that consumption of docosahexaenoic acid (DHA), an ω-3 polyunsaturated fatty acid with anti-inflammatory properties, influences the temporal profile …


Newsroom, Georgia Southern University Sep 2018

Newsroom, Georgia Southern University

Newsroom (2006-2023)

  • Georgia Southern biology professor receives National Science Foundation grant to study hormones and growth


The George-Anne Inkwell Edition, Georgia Southern University Sep 2018

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.


The Distinctive Regulatory Mechanisms Of Bacterial Acetyl-Coa Carboxylase, Alexandra Leigh Evans Sep 2018

The Distinctive Regulatory Mechanisms Of Bacterial Acetyl-Coa Carboxylase, Alexandra Leigh Evans

LSU Doctoral Dissertations

Metabolic Regulation is a complex system used to control cellular metabolism in response to conditions in the cell’s environment. For most enzymes, the cell can rely upon a minimal amount of regulation; however, critical enzymes, such as acetyl-CoA carboxylase, must be regulated at multiple levels. Acetyl-CoA carboxylase catalyzes the first committed step in fatty acid synthesis. In bacteria, acetyl-CoA carboxylase forms a complex of three subunits–biotin carboxylase, biotin carboxyl carrier protein, and carboxyltransferase–which catalyze the carboxylation of acetyl-CoA to form malonyl-CoA via two half-reactions. In the first half-reaction, biotin covalently linked to biotin carboxyl carrier protein is carboxylated by biotin …


Are We Doing More Than We Know? Possible Mechanisms Of Response To Music Therapy, Amy Clements-Cortés, Lee Bartel Sep 2018

Are We Doing More Than We Know? Possible Mechanisms Of Response To Music Therapy, Amy Clements-Cortés, Lee Bartel

Music Faculty Publications

Due to advances in medical knowledge the population of older adults struggling with issues of aging like Alzheimer’s disease (AD), Parkinson’s disease (PD), and stroke is growing. There is a need for therapeutic interventions to provide adaptive strategies to sustain quality of life, decrease neurologic impairment, and maintain or slow cognitive decline and function due to degenerative neurologic diseases. Musical interventions with adults with cognitive impairments have received increased attention over the past few years, such as the value of personalized music listening in the iPod project for AD; music as a tool to decrease agitation and anxiety in dementia; …


Does Environment Filtering Or Seed Limitation Determine Post-Fire Forest Recovery Patterns In Boreal Larch Forests?, Wen H. Cai, Zhihua Liu, Yuan Z. Yang, Jian Yang Sep 2018

Does Environment Filtering Or Seed Limitation Determine Post-Fire Forest Recovery Patterns In Boreal Larch Forests?, Wen H. Cai, Zhihua Liu, Yuan Z. Yang, Jian Yang

Forestry and Natural Resources Faculty Publications

Wildfire is a primary natural disturbance in boreal forests, and post-fire vegetation recovery rate influences carbon, water, and energy exchange between the land and atmosphere in the region. Seed availability and environmental filtering are two important determinants in regulating post-fire vegetation recovery in boreal forests. Quantifying how these determinants change over time is helpful for understanding post-fire forest successional trajectory. Time series of remote sensing data offer considerable potential in monitoring the trajectory of post-fire vegetation recovery dynamics beyond current field surveys about structural attributes, which generally lack a temporal perspective across large burned areas. We used a time series …


Method And System For Non-Invasive Optical Blood Glucose Detection Utilizing Spectral Data Analysis, Zhi Xu Sep 2018

Method And System For Non-Invasive Optical Blood Glucose Detection Utilizing Spectral Data Analysis, Zhi Xu

UMSL Patents

Systems and methods are disclosed for non-invasively measuring blood glucose levels in a biological sample based on spectral data. This includes utilizing at least one light source configured to strike a target area of a sample, utilizing at least one light filter positioned to receive light transmitted through the target area of the sample from the at least one light source, utilizing at least one light detector positioned to receive light from the at least one light source and filtered by the at least one light filter, and to generate an output signal, having a time dependent current, which is …


Ua12/2/1 College Heights Herald, Vol. 93 [94], No. 3, Wku Student Affairs Sep 2018

Ua12/2/1 College Heights Herald, Vol. 93 [94], No. 3, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

  • Zeige, Nicole. Detailing Student Government Association President’s Lawsuit Against WKU – Andi Dahmer
  • Singleton, John. We Got Caged – Cage the Elephant
  • Breu, Natasha. New Technology in Dorms Keeps Track of Housing Services
  • Hicks, Amelia. Former Professor & Civil Rights Activist Dies at 83 – Alan Anderson
  • Dobbs, Jack. Student Government Association President Prepares for a Challenging Year – Stephen Mayer
  • Maliciously Untrue? Saving Face? – Andi Dahmer
  • Coyle, Cameron. The Nun Largely Disappoints with Cheap Scares
  • Cage the Elephant on Stage
  • Fletcher, Griffin. Rite …


White Lab Develops Molecules To Deliver Carbon Monoxide And Singlet Oxygen To Cancer Cells Using Visible Light, Ohio University College Of Arts & Sciences Sep 2018

White Lab Develops Molecules To Deliver Carbon Monoxide And Singlet Oxygen To Cancer Cells Using Visible Light, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.


Alterations In Platelet Secretion Differentially Affect Thrombosis And Hemostasis, Smita Joshi, Meenakshi Banerjee, Jinchao Zhang, Akhil Kesaraju, Irina D. Pokrovskaya, Brian Storrie, Sidney W. Whiteheart Sep 2018

Alterations In Platelet Secretion Differentially Affect Thrombosis And Hemostasis, Smita Joshi, Meenakshi Banerjee, Jinchao Zhang, Akhil Kesaraju, Irina D. Pokrovskaya, Brian Storrie, Sidney W. Whiteheart

Molecular and Cellular Biochemistry Faculty Publications

We genetically manipulated the major platelet vesicle-associated membrane proteins (VAMP2, VAMP3, and VAMP8) to create mice with varying degrees of disrupted platelet secretion. As previously shown, loss of VAMP8 reduced granule secretion, and this defect was exacerbated by further deletion of VAMP2 and VAMP3. VAMP2Δ3Δ8−/− platelets also had reduced VAMP7. Loss of VAMP2 and VAMP3 (VAMP2Δ3Δ) had a minimal impact on secretion when VAMP7 and VAMP8 were present. Integrin αIIbβ3 activation and aggregation were not affected, although spreading was reduced in VAMP2Δ3Δ8−/− platelets. Using these mice …


Methods For Treating Neuropathic Pain, Joseph R. Holtman, Peter Anthony Crooks, Linda Phyliss Dwoskin, Michael J. Mcintosh, Elzbieta Pogonowska Wala Sep 2018

Methods For Treating Neuropathic Pain, Joseph R. Holtman, Peter Anthony Crooks, Linda Phyliss Dwoskin, Michael J. Mcintosh, Elzbieta Pogonowska Wala

Pharmaceutical Sciences Faculty Patents

Provided are methods for using bis-quaternary ammonium compounds to treat inflammatory pain, neuropathic pain and nociceptive pain.


Greenhouse Gases Are Not Just Warming The Planet, They Are Also Acidifying Our Oceans, Staff Sep 2018

Greenhouse Gases Are Not Just Warming The Planet, They Are Also Acidifying Our Oceans, Staff

Browse All News

No abstract provided.