Digital Commons Network^™

Preprints, Institutional Repositories, And The Version Of Record, Judy Luther, Ivy Anderson, Monica Bradford, John Inglis

Charleston Library Conference

No abstract provided.

A Simpler Path To Public Access Compliance, Howard Ratner, David Crotty, Jack Maness, Judith Russell

Charleston Library Conference

No abstract provided.

Chemical Analysis Of Precipitation And Stormwater Runoff From A Large Green Roof, Kimberly Fitzgerald, Alexander Johnson, Cliff I. Davidson

International Building Physics Conference 2018

The growth medium of a green roof is likely to affect the chemistry of the rainwater passing through it, which may impact the receiving waters. Currently only limited data exist on the changes in rain chemistry caused by green roofs. The objectives of this project are to determine the differences in concentration of several contaminants in rain and in runoff from a green roof in downtown Syracuse, NY, and to explore reasons for the observed differences. A few samples were collected in 2014 and 2016, but most of the data are from 2017. Collection of precipitation uses funnels, while collection …

New Technology Creates New Lightscape, Jianzhen Qiu, Shuoxian Wu

International Building Physics Conference 2018

Light is a key element of our world’s beauty. Chinese scholar Wu Shuoxian put forward the concept of “Lightscape”, and proposed its research as a parallel discipline of the “Soundscape”. As a special aspect of the visual-scape, lightscape can give us a comprehensive and multi-disciplinary perspective of living environment. Many traditional lightscape cases have always been remembered as the representations of specific regional cultures. This article presents several cases of modern lightscape created with new technologies and methods. Included in these cases are: outstanding lightscape and art installments created by artists using light as a key element and fulfilled with …

Long Term Measurements And Ham Modelling Of An Interior Insulation Solution For An Office Building In Cold Climate, Paul Klõšeiko, Targo Kalamees

International Building Physics Conference 2018

Excessive mould damage was detected in an office building in Northern Europe and thus a renovation need was established. This paper studies a renovation solution using measurements and heat, air & moisture (HAM) modelling. Polyurethane (PUR) foam was used to fill the air gap in masonry while capillary active calcium silicate (CaSi) insulation was used on the interior surface at thermal bridges. During renovation works temperature and relative humidity (t&RH) and heat flux sensors were installed throughout the wall. Nearly 3 years of measurements are presented. Average thermal transmittance (U) of the wall was reduced around 3 times. While the …

The Effect Of Human Walking On Distribution Characteristics Of Indoor Particulate Matter, Yang Lv, Haifeng Wang, Hiroshi Yoshino, Hiroshi Yonekura, Rie Takaki, Genta Kurihara

International Building Physics Conference 2018

In modern society, house dust particulate matters pollution had become serious. Ventilation is an important method for removing house dust particulate matters and it is very important to explore the removal efficiency of house dust particulate matters under different ventilation modes. This study analyses the removal effect of house dust particulate matters under the two typical ventilation modes called ceiling exhaust and slit exhaust strategy through experiments and date analysis. In the process of experiments, riboflavin particles were used as the house dust particulate matters, instantaneous microbial detection (IMD) was used to measure the house dust particulate matters. Walking test …

Understanding Swelling Of Wood Through Multiscale Modeling, Dominique Derome, Chi Zhang, Mingyang Chen, Jan Carmeliet

International Building Physics Conference 2018

Wood is a well-used building material where the capacity of wood to absorb water leads to swelling and reduced mechanical properties, and also to questions of durability. The origin of the hygroscopic behavior of wood lies at the nanoscale material that composes its cell walls. Using atomistic modeling, we study the hygromechanical behavior of the different polymeric components of wood, separately and in aggregate configurations. We report the coupled effects of water sorption on the hygric and mechanical properties of the S2 cell wall layer and we upscale the findings using a poromechanical framework.

Movements Of Translocated And Nontranslocated Canada Geese In Georgia Estimated Using Band Recoveries, Morgan S. Donaldson, Gregory D. Balkcom, Michael J. Chamberlain

Georgia Journal of Science

Overabundant populations of resident Canada geese (Branta canadensis) are an increasing source of human-wildlife complaints throughout the species’ range. Many resident geese exploit urban areas, and translocation is one method of reducing nuisance problems associated with resident Canada geese. Translocated geese have similar harvest rates but lower survival rates than nontranslocated geese. To examine relationships between distance moved and the age, sex, and status of geese, we evaluated distances from banding sites to recovery sites for resident geese banded in Georgia, USA, during 2001–2015. We assessed potential differences in movements between rural and urban, and nontranslocated and translocated geese, …

The Use Of A Large, Extensive Green Roof For Multiple Research Objectives, Cliff I. Davidson, Carli D. Flynn, Charitha Gunawardana, Alexander J. Johnson, Mallory N. Squier, Lucie L. Worthen, Yige Yang

International Building Physics Conference 2018

The Green Roof on the Onondaga County Convention Center in Syracuse, NY is planted with several varieties of sedum over an area of 0.56 hectares. The roof was constructed in 2011, and has been instrumented with sensors to enable research and education over an extended period. The purpose of the current work on this roof is to quantify its performance with respect to water storage and energy transfer, and to identify chemical constituents in the runoff that might be contributed by the growth medium. The scope of the project also includes a number of measurements on traditional roofs in the …

Comparing Exterior Wall Finishes Using Life-Cycle Assessment, Brandi Dodge, Rui Liu

International Building Physics Conference 2018

Selecting products that are environmentally friendly can help reduce the negative environmental impacts associated with the built environment. However, the process can be difficult. Life-cycle assessment (LCA) is an approach used to measure the environmental performance of a product or service by considering all stages of a product’s life-cycle from extraction of raw materials to its end of life. Many products that claim to be environmentally friendly are based on a single life-cycle stage or environmental impact. These claims are often misleading as they do not consider other life-cycle stages or other environmental impacts associated with the products. This study …

Experimental Study On The Stomatal Resistance Of Green Roof Vegetation Of Semiarid Climates For Building Energy Simulations, Ursula Steinfort, Rocío Arriola-Cepeda, Sergio Vera, Francisco Albornoz

International Building Physics Conference 2018

Current modelling approaches for energy simulations in green roofs use a range of values for parameters such as stomatal resistance (rs) of the vegetation. rs reflects the capability of a plant to transpire, thus it has a direct relation to the cooling potential of green roofs in buildings. Therefore, rs values need to be revised based on differences among species and contrasting environmental conditions, considering anatomical and physiological characteristics among species and their changes throughout the day. In order to provide real data on species commonly used for green roofs in semiarid climates, this paper aims to evaluate the stomatal …

Gsu View, September 25, 2018, Office Of Marketing And Communications

GSU View

No abstract provided.

Executive Committee - Meeting Minutes, 9/25/2018, Academic Senate

Academic Senate Minutes

No abstract provided.

Analysis Of Some Problematic Situations In Uzbek, F. I. Khakimova, A. Sh. Esanov

Central Asian Problems of Modern Science and Education

In this article, authors discuss the issues related to the creation of language corpus of Uzbek Language. In this regard, the matter, such as the collection of language units in the corpus, different national corpus and difficulties in creating the corpus of Uzbek language, are thoroughly analyzed and a number of proposals are suggested.

A Celebration Of Faculty Scholarship - 2018, Dean's Office, College Of The Holy Cross

Annual Bibliography of Faculty Publications

A listing of the scholarly and creative work produced by the faculty of the College of the Holy Cross. It includes articles, book chapters, productions, exhibitions, grants, reviews and other forms of scholarship reported for the 2017-2018 academic year.

Leading In Legacy: A History Of Concordia University, St. Paul, 1993-2018, Thomas Saylor

Concordia University, Saint Paul Histories

This university history illustrates 25 years of Concordia University, Saint Paul from 1993 to 2018. Historian Thomas Saylor uses interviews with faculty, staff, students, and administration to provide rich insights into CSP's innovation in higher education through academics, athletics, and urban location. The book is bursting with images and is a vibrant narrative of the institution's legacy.

Leading in Legacy: A History of Concordia University, St. Paul, 1993-2018 by Thomas Saylor is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Rational Identification Of A Cdc42 Inhibitor Presents A New Regimen For Long- Term Hematopoietic Stem Cell Mobilization, Wei Liu, Wei Du, Xun Shang, Lei Wang, Chris Evelyn, Maria Carolina Florian, Marnie A. Ryan, Ahmad Rayes, Xueheng Zhao, Kenneth Setchell, Jarek Meller, Fukun Guo, Nicolas Nassar, Hartmut Geiger, Qishen Pang, Yi Zheng

Clinical and Translational Science Institute

Mobilization of hematopoietic stem cells (HSCs) from bone marrow (BM) to peripheral blood (PB) by cytokine granulocyte colony-stimulating factor (G-CSF) or the chemical antagonist of CXCR4, AMD3100, is important in the treatment of blood diseases. Due to clinical conditions of each application, there is a need for continued improvement of HSC mobilization regimens. Previous studies have shown that genetic ablation of the Rho GTPase Cdc42 in HSCs results in their mobilization without affecting survival. Here we rationally identified a Cdc42 activity-specific inhibitor (CASIN) that can bind to Cdc42 with submicromolar affinity and competitively interfere with guanine nucleotide exchange activity. CASIN …

Spartan Daily September 25, 2018, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2018

Volume 151, Issue 15

Polymer Interfaces And Biopharmaceuticals: Chemistry, Designs And Challenges, David W. Grainger

Single-Use Technologies III: Scientific and Technological Advancements

The complex interactions between biological components and polymer materials has an extensive technical history. Virtually every surface property has been invoked as being important to biological interfacial response: texture, roughness, topology, porosity, hydrophilic, hydrophobic, polar, apolar, (non)-wettable, non-fouling brushes, surface mobility, rigidity, flexibility, crystalline versus amorphous, aspect ratio. Few surface properties alone, however, provide consistent, global technical solutions to vexing biomedical technology problems, particularly with cell culture, blood, plasma, microbial milieu, and protein solutions. Bio-interface materials performance must therefore be tailored specifically to each application. Short-term contact use (minutes/hours) has different materials interface requirements than long-term (days) use; globular proteins …

Method And System For Non-Invasive Optical Blood Glucose Detection Utilizing Spectral Data Analysis, Zhi Xu

UMSL Patents

Systems and methods are disclosed for non-invasively measuring blood glucose levels in a biological sample based on spectral data. This includes utilizing at least one light source configured to strike a target area of a sample, utilizing at least one light filter positioned to receive light transmitted through the target area from the at least one light source, utilizing at least one light detector positioned to receive light from the at least one light source and filtered by the at least one light filter, and to generate an output signal, having a time dependent current, which is indicative of the …

Multiple Puf Proteins Regulate The Stability Of Ribosome Biogenesis Transcripts, Anthony Fischer, Wendy Olivas

Biology Department Faculty Works

Cells must make careful use of the resources available to them. A key area of cellular regulation involves the biogenesis of ribosomes. Transcriptional regulation of ribosome biogenesis factor genes through alterations in histone acetylation has been well studied. This work identifies a post-transcriptional mechanism of ribosome biogenesis regulation by Puf protein control of mRNA stability. Puf proteins are eukaryotic mRNA binding proteins that play regulatory roles in mRNA degradation and translation via association with specific conserved elements in the 3ʹ untranslated region (UTR) of target mRNAs and with degradation and translation factors. We demonstrate that several ribosome biogenesis factor mRNAs …

Able: Blockwise Site Frequency Spectrafor Inferring Complex Population Histories And Recombination, Champak R. Beeravolu, Michael J. Hickerson, Laurent A. F. Frantz, Konrad Lohse

Publications and Research

We introduce ABLE (Approximate Blockwise Likelihood Estimation), a novel simulation-based composite likelihood method that uses the blockwise site frequency spectrum to jointly infer past demography and recombination. ABLE is explicitly designed for a wide variety of data from unphased diploid genomes to genome-wide multi-locus data (for example, RADSeq) and can also accommodate arbitrarily large samples. We use simulations to demonstrate the accuracy of this method to infer complex histories of divergence and gene flow and reanalyze whole genome data from two species of orangutan. ABLE is available for download at https://github.com/champost/ABLE.

College Voice Vol. 42 No. 1 [September 25, 2018], Connecticut College

2018-2019

No abstract provided.

Fine Mapping Of Mhc Region In Lung Cancer Highlights Independent Susceptibility Loci By Ethnicity., Aida Ferreiro-Iglesias, Corina Lesseur, James Mckay, Rayjean J Hung, Younghun Han, Xuchen Zong, David Christiani, Mattias Johansson, Xiangjun Xiao, Yafang Li, David C Qian, Xuemei Ji, Geoffrey Liu, Neil Caporaso, Ghislaine Scelo, David Zaridze, Anush Mukeriya, Milica Kontic, Simona Ognjanovic, Jolanta Lissowska, Małgorzata Szołkowska, Beata Swiatkowska, Vladimir Janout, Ivana Holcatova, Ciprian Bolca, Milan Savic, Miodrag Ognjanovic, Stig Egil Bojesen, Xifeng Wu, Demetrios Albanes, Melinda C Aldrich, Adonina Tardon, Ana Fernandez-Somoano, Guillermo Fernandez-Tardon, Loic Le Marchand, Gadi Rennert, Chu Chen, Jennifer Doherty, Gary Goodman, Heike Bickeböller, H-Erich Wichmann, Angela Risch, Albert Rosenberger, Hongbing Shen, Juncheng Dai, John K Field, Michael Davies, Penella Woll, M Dawn Teare, Lambertus A Kiemeney, Erik H F M Van Der Heijden, Jian-Min Yuan, Yun-Chul Hong, Aage Haugen, Shanbeh Zienolddiny, Stephen Lam, Ming-Sound Tsao, Mikael Johansson, Kjell Grankvist, Matthew B Schabath, Angeline Andrew, Eric Duell, Olle Melander, Hans Brunnström, Philip Lazarus, Susanne Arnold, Stacey Slone, Jinyoung Byun, Ahsan Kamal, Dakai Zhu, Maria Teresa Landi, Christopher I Amos, Paul Brennan

Articles, Abstracts, and Reports

Lung cancer has several genetic associations identified within the major histocompatibility complex (MHC); although the basis for these associations remains elusive. Here, we analyze MHC genetic variation among 26,044 lung cancer patients and 20,836 controls densely genotyped across the MHC, using the Illumina Illumina OncoArray or Illumina 660W SNP microarray. We impute sequence variation in classical HLA genes, fine-map MHC associations for lung cancer risk with major histologies and compare results between ethnicities. Independent and novel associations within HLA genes are identified in Europeans including amino acids in the HLA-B*0801 peptide binding groove and an independent HLA-DQB1*06 loci group. In …

Using Transcriptomics To Enable A Plethodontid Salamander (Bolitoglossa Ramosi) For Limb Regeneration Research, Claudia M. Arenas Gómez, Ryan M. Woodcock, Jeramiah J. Smith, Randal S. Voss, Jean Paul Delgado

Biology Faculty Publications

Background: Tissue regeneration is widely distributed across the tree of life. Among vertebrates, salamanders possess an exceptional ability to regenerate amputated limbs and other complex structures. Thus far, molecular insights about limb regeneration have come from a relatively limited number of species from two closely related salamander families. To gain a broader perspective on the molecular basis of limb regeneration and enhance the molecular toolkit of an emerging plethodontid salamander (Bolitoglossa ramosi), we used RNA-Seq to generate a de novo reference transcriptome and identify differentially expressed genes during limb regeneration.

Results: Using paired-end Illumina sequencing technology and Trinity …

Automated Foam Control In Single-Use Bioreactors Using The Single Use Foam Probe, Jordan Cobia, Ben Madsen, Emilee Madsen, Alex Hodge

Single-Use Technologies III: Scientific and Technological Advancements

Headspace foam in bioreactors can cause significant issues to a biological process among which are unfavorable metabolic conditions for cells, increased shear from bursting bubbles, cell death/entrainment, mass transfer interference and potential fouling of exhaust filters which can allow a point of entry for contamination or lead to pressure build-up and possible failure of the bioprocess container. This study investigates the efficacy of using a single use foam probe coupled with an automated response of an antifoam addition with an integrated DeltaV controller. Two 50L S.U.B.s run in parallel clearly illustrate differences; the first employing foam control using the foam …

Career Corner: Szinte Gets Ohio Epa Scholarship 2019 Applications Due, Jan 15, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Two New Endowments Focus On Transforming Safety In Engineering, Staff

Browse All News

No abstract provided.

Bfd, A New Class Of [2fe-2s] Protein That Functions In Bacterial Iron Homeostasis, Requires A Structural Anion Binding Site, Harshani Wijerathne, Huili Yao, Yan Wang, Scott Lovell, Kevin P. Battaile, Mario Rivera

Faculty Publications

Copyright © 2018 American Chemical Society. Mobilization of iron from bacterioferritin (BfrB) requires specific interactions with a [2Fe-2S] ferredoxin (Bfd). Blocking the BfrB:Bfd interaction results in irreversible iron accumulation in BfrB and iron deficiency in the cytosol [Eshelman, K., et al. (2017) Metallomics 9, 646-659]. The only known Bfd structure, which was obtained in complex with BfrB (Protein Data Bank entry 4E6K), indicated a new fold and suggested that the stability of Bfd is aided by an anion binding site consisting of R26, R29, and K46. We investigated the Bfd fold using site-directed mutagenesis, X-ray crystallography, and biochemistry in solution. …

Quantifying Climate Sensitivity And Climate-Driven Change In North American Amphibian Communities, David A. W. Miller, Evan H Campbell Grant, Erin Muths, Staci M. Amburgey, Michael J. Adams, Maxwell B. Joseph, J. Hardin Waddle, Pieter T. J. Johnson, Maureen E. Ryan, Benedikt R. Schmidt, Daniel L. Calhoun, Courtney L. Davis, Robert N. Fisher, David M. Green, Blake R. Hossack, Tracy A. G. Rittenhouse, Susan C. Walls, Larissa L. Bailey, Sam S. Cruickshank, Gary M. Fellers, Thomas A. Gorman, Carola A. Haas, Ward Hughson, David S. Pilliod, Steve J. Price, Andrew M. Ray, Walt Sadinski, Daniel Saenz, William J. Barichivich, Adrianne Brand

Forestry and Natural Resources Faculty Publications

Changing climate will impact species’ ranges only when environmental variability directly impacts the demography of local populations. However, measurement of demographic responses to climate change has largely been limited to single species and locations. Here we show that amphibian communities are responsive to climatic variability, using > 500,000 time-series observations for 81 species across 86 North American study areas. The effect of climate on local colonization and persistence probabilities varies among eco-regions and depends on local climate, species life-histories, and taxonomic classification. We found that local species richness is most sensitive to changes in water availability during breeding and changes in …