Digital Commons Network^™

Bending The Arc Toward Justice: 50 Years Of Black Student Activism At Usf, Adrienne Riley

Black Student Union

Opening Remarks by Adrienne Riley for the 50th Anniversary Event for University of San Francisco's Black Student Union, November 9th, 2018.

Investigative Study On Nitric Oxide Production In Human Dermal Fibroblast Cells Under Normal And High Glucose Conditions, Maria P. Kwesiga, Emily Cook, Jennifer Hannon, Sarah Wayward, Caroline Gwaltney, Smitha Rao, Megan Frost

Peer Reviewed Articles

Diabetic foot ulcers (DFU) are a major health problem associated with diabetes mellitus. Impaired nitric oxide (NO) production has been shown to be a major contributor to the dysregulation of healing in DFU. The level of impairment is not known primarily due to challenges with measuring NO. Herein, we report the actual level of NO produced by human dermal fibroblasts cultured under normal and high glucose conditions. Fibroblasts produce the extracellular matrix, which facilitate the migration of keratinocytes to close wounds. The results show that NO production was significantly higher in normal glucose compared to high glucose conditions. The real-time …

Biology Graduate Students Present At Annual Society For Neuroscience, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Environmental Impact- Using Digital Media To Focus Student Learning, Crystal Randall, Sowmya Anjur, Donald Dosch

Faculty Publications & Research

Environmental issues are global challenges that our students will have to address in their future. Addressing these issues through curriculum helps bring purpose to students’ learning. We have developed a capstone project in our introductory biology class that allows students to engage in these issues in a creative and personalized manner, and which asks students to not only address the biology at the core of these issues but also suggest possible solutions to the problem. In this session, we will share how we scaffold our curriculum to prepare students for this experience, as well as show examples of student work.

Predicting Response To Platin Chemotherapy Agents With Biochemically-Inspired Machine Learning, Peter Rogan, Eliseos J. Mucaki, Dan Lizotte

Biochemistry Publications

Selection of effective genes that accurately predict chemotherapy response could improve cancer outcomes. We compare optimized gene signatures for cisplatin, carboplatin, and oxaliplatin response in the same cell lines, and respectively validate each with cancer patient data. Supervised support vector machine learning was used to derive gene sets whose expression was related to cell line GI₅₀ values by backwards feature selection with cross-validation. Specific genes and functional pathways distinguishing sensitive from resistant cell lines are identified by contrasting signatures obtained at extreme vs. median GI₅₀ thresholds. Ensembles of gene signatures at different thresholds are combined to reduce dependence …

Sediment Texture And Composition Of Sediment Cores Collected During R/V Weatherbird Ii Cruises In The Northern Gulf Of Mexico From 2010-11-18 To 2016-09-09, Gregg R. Brooks, Rebekka A. Larson

C-IMAGE data

Sediment texture and composition data were generated for selected core sub-samples at 2mm sampling intervals for “surficial unit” and 5mm sampling resolution intervals to base of cores. Sediment texture values are expressed as % Gravel, % Sand, % Silt and % Clay as calculated by dry weight (g). % Mud can be calculated by combining % Silt and % Clay. Sediment composition is expressed as % carbonate content measured by acid leaching. This dataset supports the publication: Larson, R. A., Brooks, G. R., Schwing, P. T., Holmes, C. W., Carter, S. R., & Hollander, D. J. (2018). High-resolution investigation of …

Environmental Health And Saafety For Scientists Bps 357x, Joanna Burkhardt

Library Impact Statements

No abstract provided.

Diversity And Inclusion In The Science Classroom, Sowmya Anjur

Faculty Publications & Research

A Diversity, Epidemiology and social justice unit was incorporated into the Physiology and Disease curriculum in Fall 2016. Students discussed topics such as social and cultural influences on diversity thinking, and selective treatment in hospitals based on race. It was very noteworthy that students were united in their thinking regarding diversity and inclusion, despite the fact that they were from different backgrounds and diverse cultures. In 2017, additional discussions were held on equity in education. Students who were otherwise reserved were encouraged enough to express their views, and everyone appreciated the fact that they had been included.

Research Team Gets Award For Problem-Solving On International Space Station, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Investigative Study On Nitric Oxide Production In Human Dermal Fibroblast Cells Under Normal And High Glucose Conditions, Maria Paula Kwesiga, Emily Cook, Jennifer Hannon, Sarah Wayward, Caroline Gwaltney, Smitha Rao, Megan C. Frost

Michigan Tech Publications, Part 1

Diabetic foot ulcers (DFU) are a major health problem associated with diabetes mellitus. Impaired nitric oxide (NO) production has been shown to be a major contributor to the dysregulation of healing in DFU. The level of impairment is not known primarily due to challenges with measuring NO. Herein, we report the actual level of NO produced by human dermal fibroblasts cultured under normal and high glucose conditions. Fibroblasts produce the extracellular matrix, which facilitate the migration of keratinocytes to close wounds. The results show that NO production was significantly higher in normal glucose compared to high glucose conditions. The real-time …

Short-Lived Radioisotope Geochronology From Sediment Cores Collected During R/V Weatherbird Ii Cruises In The Northern Gulf Of Mexico From 2010-11-18 To 2016-09-09, Gregg R. Brooks, Rebekka A. Larson

C-IMAGE data

Short-lived Radioisotope (SLRad) data were generated for selected core sub-samples at 2mm sampling intervals for “surficial unit” and 5mm sampling resolution intervals to base of cores. SLRad data generated include sample activity as disintegrations per minute per gram (dpm/g) of: 1) Excess 234Th (234Thxs) activity, which is calculated by measuring the total 234Th (234ThTot) activity and the subtraction of the measured or estimated “Supported” 234Th (234ThSup) activity, 2) Excess 210Pb (210Pbxs) activity, which is calculated by measuring the total 210Pb (210PbTot) activity and subtraction of the measured background 210Pb (210PbSup) activity (average of 214Pb at 295keV, 214Pb at 351keV, and …

Analysis Of Environment-Marker Associations In American Chestnut, Markus Müller, Charles Dana Nelson, Oliver Gailing

Forest Health Research and Education Center Faculty Publications

American chestnut (Castanea dentata Borkh.) was a dominant tree species in its native range in eastern North America until the accidentally introduced fungus Cryphonectria parasitica (Murr.) Barr, that causes chestnut blight, led to a collapse of the species. Different approaches (e.g., genetic engineering or conventional breeding) are being used to fight against chestnut blight and to reintroduce the species with resistant planting stock. Because of large climatic differences within the distribution area of American chestnut, successful reintroduction of the species requires knowledge and consideration of local adaptation to the prevailing environmental conditions. Previous studies revealed clear patterns of genetic …

Ucc Minutes Nov 9, 2018, Undergraduate Curriculum Committee

Undergraduate Currirculum Committee Minutes

No abstract provided.

Factors Affecting Trailer Thermal Environment Experienced By Market Pigs Transported In The Us, Y Xiong, Richard S. Gates, Angela R. Green-Miller

Department of Animal Science: Faculty Publications

Extreme weather conditions challenge pig thermoregulation during transport and are addressed by the National Pork Board (NPB) Transport Quality Assurance® (TQA) program that provides guidelines for trailer boarding, bedding, and misting. These guidelines are widely applied, yet very little is known about the microenvironment within the trailer. In this study, TQA guidelines (V4) were evaluated via extensive thermal environment measurements during transport in order to evaluate spatial variability and implications on ventilation pattern. Effects of trailer management strategies including bedding, boarding, and misting were examined and the trailer was monitored for interior temperature rise and THI responses within six separate …

Systems Thinking In A Second Grade Curriculum: Students Engaged To Address A Statewide Drought, Margaret Sauceda Curwen, Amy Ardell, Laurie Macgillivray, Rachel Lambert

Education Faculty Articles and Research

Faced with issues, such as drought and climate change, educators around the world acknowledge the need for developing students’ ability to solve problems within and across contexts. A systems thinking pedagogy, which recognizes interdependence and interconnected relationships among concrete elements and abstract concepts (Meadows, 2008; Senge et al., 2012), has potential to transform the classroom into a space of observing, theorizing, discovering, and analyzing, thus linking academic learning to the real world. In a qualitative case study in one school located in a major metropolitan area in California, USA teachers and their 7- and 8-year-old students used systems thinking in …

Demonstration Of Monolithic-Silicon Carbide (Sic) Neural Devices, Evans K. Bernardin

USF Tampa Graduate Theses and Dissertations

Brain Machine Interfaces (BMI) provide a communication pathway between the electrical conducting units of the brain (neurons) and external devices. BMI technology may provide improved neurological and physiological functions to patients suffering from disabilities due to damaged nervous systems. Unfortunately, microelectrodes used in Intracortical Neural Interfaces (INI), a subset of the BMI device family, have yet to demonstrate long-term in vivo performance due to material, mechanical and electrical failures. Many state-of-the-art INI devices are constructed using stacks of multiple materials, such as silicon (Si), titanium (Ti), platinum (Pt), parylene C, and polyimide. Not only must each material tolerate the biological …

Association Of The Haptoglobin Gene Polymorphism With Cognitive Function And Decline In Elderly African American Adults With Type 2 Diabetes: Findings From The Action To Control Cardiovascular Risk In Diabetes–Memory In Diabetes (Accord-Mind) Study, Michael Beeri, Hung-Mo Lin, Mary Sano, Ramit Ravona-Springer, Xiaoyu Liu, Barbara B. Bendlin, Carey E. Gleason, Elizabeth Guerrero-Berroa, Laili Soleimani, Lenore J. Launer, Scott Ehrenberg, Orit Lache, Yaakov K. Seligman, Andrew P. Levy

Publications and Research

IMPORTANCE African American individuals have higher dementia risk than individuals of white race/ethnicity. They also have higher rates of type 2 diabetes, which may contribute to this elevated risk. This study examined the association of the following 2 classes of alleles at the haptoglobin (Hp) locus that are associated with poor cognition, cardiovascular disease, and mortality: Hp 1-1 (associated with poor cognition and cerebrovascular disease) and Hp 2-1 and Hp 2-2 (associated with greater risk ofmyocardial infarction and mortality). An additional polymorphism in the promoter region of the Hp 2 allele, restricted to individuals of African descent, yields a fourth …

Daily Eastern News: November 09, 2018, Eastern Illinois University

November

No abstract provided.

College Faculty In The News: November 9, 2018, University Of Dayton

College of Arts and Sciences Newsroom

Professor Jana Bennett, Department of Religious Studies, discusses the place for religious tradition in the abstract world of online social media.

A Secure Computing Platform For Building Automation Using Microkernel-Based Operating Systems, Xiaolong Wang

USF Tampa Graduate Theses and Dissertations

Building Automation System (BAS) is a complex distributed control system that is widely deployed in commercial, residential, industrial buildings for monitoring and controlling mechanical/electrical equipment. Through increasing industrial and technological advances, the control components of BAS are becoming increasingly interconnected. Along with potential benefits, integration also introduces new attack vectors, which tremendous increases safety and security risks in the control system. Historically, BAS lacks security design and relies on physical isolation and "security through obscurity". These methods are unacceptable with the "smart building" technologies. The industry needs to reevaluate the safety and security of the current building automation system, and …

A Comparative Study Of Defeasible Argumentation And Non-Monotonic Fuzzy Reasoning For Elderly Survival Prediction Using Biomarkers, Lucas Rizzo, Ljiljana Majnaric, Luca Longo

Conference papers

Computational argumentation has been gaining momentum as a solid theoretical research discipline for inference under uncertainty with incomplete and contradicting knowledge. However, its practical counterpart is underdeveloped, with a lack of studies focused on the investigation of its impact in real-world settings and with real knowledge. In this study, computational argumentation is compared against non-monotonic fuzzy reasoning and evaluated in the domain of biological markers for the prediction of mortality in an elderly population. Different non-monotonic argument-based models and fuzzy reasoning models have been designed using an extensive knowledge base gathered from an expert in the field. An analysis of …

The Echo: November 9, 2018, Taylor University

2018-2019 (Volume 106)

New diversity position created – Taylor joins Colleges Against Cancer – Alumnus receives teaching fellowship – Lesner speaks on nonprofits – Trevor Osswald’s photos of the week – Bree’s Beat International News – Correction – Ivy and a son named Levi – Student hold each other’s stories – ‘Prevention is really our best medicine – croc thoughts – The Weekly Bachelor and Bachelorette – Humans of Taylor U – Weekly Crossword – Sudoku -- #TaylorU’s Top Tweets – Learn the art of looking through the eyes of another – Stories walk ‘Into the Woods’ and onto the stage – Discover …

A Common Genetic Mechanism Underlies Morphological Diversity In Fruits And Other Plant Organs, Shan Wu, Biyao Zhang, Neda Keyhaninejad, Gustavo R. Rodríguez, Hyun Jung Kim, Manohar Chakrabarti, Eudald Illa-Berenguer, Nathan K. Taitano, M. J. Gonzalo, Aurora Díaz, Yupeng Pan, Courtney P. Leisner, Dennis Halterman, C. Robin Buell, Yiqun Weng, Shelley H. Jansky, Herman Van Eck, Johan Willemsen, Antonio J Monforte, Tea Meulia, Esther Van Der Knaap

Plant and Soil Sciences Faculty Publications

Shapes of edible plant organs vary dramatically among and within crop plants. To explain and ultimately employ this variation towards crop improvement, we determined the genetic, molecular and cellular bases of fruit shape diversity in tomato. Through positional cloning, protein interaction studies, and genome editing, we report that OVATE Family Proteins and TONNEAU1 Recruiting Motif proteins regulate cell division patterns in ovary development to alter final fruit shape. The physical interactions between the members of these two families are necessary for dynamic relocalization of the protein complexes to different cellular compartments when expressed in tobacco leaf cells. Together with data …

Submission: 2018 Legislative Review Of Export Development Canada, Sara Seck, Keith Macmaster, Penelope Simons

Articles, Book Chapters, & Popular Press

This submission to the 2018 review of Export Development Canada is informed in part by a conference and policy meeting that we hosted in October 2017 on the subject of extractive industries and the human rights of women and girls, at the Human Rights Resource Education Centre in Ottawa. This submission will reflect on some of the insights that emerged from the conference and policy meeting, as well as our own prior and subsequent research. Our submission will focus primarily on Theme 5: Corporate Social Responsibility and Human Rights, which asks whether, in fulfilling its mandate, EDC reflects the expectations …

Evaluation Of Spatial Generalization Characteristics Of A Robust Classifier As Applied To Coral Reef Habitats In Remote Islands Of The Pacific Ocean, Justin J. Gapper, Hesham El-Askary, Erik J. Linstead, Thomas Piechota

Mathematics, Physics, and Computer Science Faculty Articles and Research

This study was an evaluation of the spectral signature generalization properties of coral across four remote Pacific Ocean reefs. The sites under consideration have not been the subject of previous studies for coral classification using remote sensing data. Previous research regarding using remote sensing to identify reefs has been limited to in-situ assessment, with some researchers also performing temporal analysis of a selected area of interest. This study expanded the previous in-situ analyses by evaluating the ability of a basic predictor, Linear Discriminant Analysis (LDA), trained on Depth Invariant Indices calculated from the spectral signature of coral in one location …

Scientia: Fall 2018

Scientia

Gerald Koocher Steps Down as Dean; Calculus, Conquered; Math Magic; New Programs: We've Got a Degree in That; Lab Notes; To Croatia, With Curiosity; Human Nature Inextricable from Scientific Advances; The Scientists of Summer

Generation Of Isogenic Human Pluripotent Stem Cell-Derived Neurons To Establish A Molecular Angelman Syndrome Phenotype And To Study The Ube3a Protein Isoforms, Carissa Sirois

Doctoral Dissertations

Angelman Syndrome (AS) is a neurodevelopment disorder for which there is currently no cure that is characterized by severe seizures, intellectual disability, absent speech, ataxia, and happy affect. Loss of expression from the maternally inherited copy of UBE3A, a gene regulated by genomic imprinting, causes AS. Currently there are multiple promising therapeutic approaches being explored and developed for AS, some of which involve targeting or expression of the human genetic sequence. Subsequently, it is necessary to establish robust cellular models for AS that can be used to test these, as well as future, potential AS therapies. Toward this aim, …

From Bits To Atoms: Does The Open Source Software Model Translate To Open Source Hardware?, Beldiman, Dana

Santa Clara High Technology Law Journal

From Bits to Atoms: Does the Open Source Software Model

Translate to Open Source Hardware?

Structure-Based Design, Synthesis And Applications Of A New Class Of Peptidomimetics: 'Y-Aa Peptides And Their Derivatives, Ma Su

USF Tampa Graduate Theses and Dissertations

Peptidomimetics can mimic hierarchical structures of peptides and proteins. Thus, they are extensively studied for therapeutic applications. To break the limitation of backbones and frameworks and expand the peptidomimetics family, a new class of peptidomimetics - “γ-AApeptides” was developed. Design of γ-AApeptides is based on the chiral peptide nucleic acids (PNAs) backbone.

The World Health Organization estimates that one -third of all deaths in the world are on account of infectious diseases. AMPs are important because of their high activity against broad spectrum microbes, less susceptible to grow resistance and selectivity in binding to bacterial cells over human cells. γ-AApeptides …

Redox Regulation Of Type-I Inositol Trisphosphate Receptors In Intact Mammalian Cells., Suresh K. Joseph, Michael P. Young, Kamil Alzayady, David I. Yule, Mehboob Ali, David M. Booth, György Hajnóczky

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

A sensitization of inositol 1,4,5-trisphosphate receptor (IP3R)-mediated Ca2+ release is associated with oxidative stress in multiple cell types. These effects are thought to be mediated by alterations in the redox state of critical thiols in the IP3R, but this has not been directly demonstrated in intact cells. Here, we utilized a combination of gel-shift assays with MPEG-maleimides and LC-MS/MS to monitor the redox state of recombinant IP3R1 expressed in HEK293 cells. We found that under basal conditions, ∼5 of the 60 cysteines are oxidized in IP3R1. Cell treatment with 50 μm thimerosal altered gel shifts, indicating oxidation of ∼20 cysteines. …