Digital Commons Network^™

Functional Brain Activation Changes Associated With Practice In Delaying Smoking Among Moderate To Heavy Smokers: Study Protocol And Rationale Of A Randomized Trial (Cope)., Andrew T. Fox, Delwyn Catley, Kimber P. Richter, Edward F. Ellerbeck, Morgan G. Brucks, Vlad B. Papa, Laura E. Martin

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Most smokers struggle to overcome tobacco addiction. Neuroscientific models of addiction emphasize the importance of brain regions associated with cognitive control and reward to understand the cycle of addiction and relapse. During an attempt at abstinence, the cognitive control system appears to be underpowered to override the heightened reward system of the addicted brain. Thus, one neural target for treatment is to strengthen the cognitive control system. It may be possible to improve the functioning of the cognitive control system via deliberate practice.

METHODS/DESIGN: This study will determine the effects of practicing delaying smoking on brain and behavioral measures …

Modulation Of Auxin And Cytokinin Responses By Early Steps Of The Phenylpropanoid Pathway, Jasmina Kurepa, Timothy E. Shull, Sumudu S. Karunadasa, Jan A. Smalle

Plant and Soil Sciences Faculty Publications

Background: The phenylpropanoid pathway is responsible for the synthesis of numerous compounds important for plant growth and responses to the environment. In the first committed step of phenylpropanoid biosynthesis, the enzyme phenylalanine ammonia-lyase (PAL) deaminates L-phenylalanine into trans-cinnamic acid that is then converted into p-coumaric acid by cinnamate-4-hydroxylase (C4H). Recent studies showed that the Kelch repeat F-box (KFB) protein family of ubiquitin ligases control phenylpropanoid biosynthesis by promoting the proteolysis of PAL. However, this ubiquitin ligase family, alternatively named Kiss Me Deadly (KMD), was also implicated in cytokinin signaling as it was shown to promote the degradation of …

Spatial Variation In Throughfall, Soil, And Plant Water Isotopes In A Temperate Forest, Gregory R. Goldsmith, Scott T. Allen, Sabine Braun, Nadine Engbersen, Clara Romero González-Quijano, James W. Kirchner, Rolf T. W. Siegwolf

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Studies of stable isotopes of water in the environment have been fundamental to advancing our understanding of how water moves through the soil‐plant‐atmosphere continuum; however, much of this research focuses on how water isotopes vary in time, rather than in space. We examined the spatial variation in the δ¹⁸O and δ²H of throughfall and bulk soil water, as well as branch xylem and bulk leaf water of Picea abies (Norway Spruce) and Fagus sylvatica (Beech), in a 1 ha forest plot in the northern Alps of Switzerland. Means and ranges of water isotope ratios varied considerably …

No Evidence For Kin Protection In The Expression Of Sickness Behaviors In House Mice, Patricia C. Lopes, Per Block, Alice Pontiggia, Anna K. Lindholm, Barbara König

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

When infected, animals change their behaviors in several ways, including by decreasing their activity, their food and water intake, and their interest in social interactions. These behavioral alterations are collectively called sickness behaviors and, for several decades, the main hypotheses put forward to explain this phenomenon were that engaging in sickness behaviors facilitated the fever response and improved the likelihood of host survival. However, a new hypothesis was recently proposed suggesting that engaging in sickness behaviors may serve to protect kin. We tested this kin protection hypothesis by combining a field and a laboratory experiment in house mice. In both …

Long-Term Impacts Of Exotic Grazer Removal On Native Shrub Recovery, Santa Cruz Island, California, Stephanie G. Yelenik

Western North American Naturalist

A combination of overgrazing and exotic species introduction has led to the degradation of habitats worldwide. It is often unclear whether removal of exotic ungulates will lead to the natural reestablishment of native plant communities without further management inputs. I describe here my return to sites on Santa Cruz Island, California, 12 years after initial sampling in order to gain a long-term view on native shrub reestablishment into exotic grasslands after exotic grazer removal. Santa Cruz Island was grazed by feral sheep and cattle for over a century; these exotic grazers were removed in the late 1980s and feral pigs …

Tourism And Recreation In A Warmer Indiana: A Report From The Indiana Climate Change Impacts Assessment, Jonathon Day, Melissa Widhalm, Natalie Chin, Leslie Dorworth, Kalim Shah, Sandra Sydnor, Jeffrey Dukes

Tourism Reports

Indiana’s climate and geography make it an attractive place for outdoor tourism and recreation. Many months of each year are ideal for boating, fishing, swimming, hiking, camping, and taking in outdoor sporting events or festivals.

But the world’s climate is changing, and Indiana’s is no exception. Temperature increases already seen over the last hundred years will accelerate, potentially through the end of this century, and precipitation patterns will change. Those changes will affect the many facets of tourism and recreation throughout the state, including the types of tourism the state can offer, the timing of events, and the quality of …

Augustine's Confessiones: The Battle Between Two Conversions, Robert Hunter Craig

USF Tampa Graduate Theses and Dissertations

There are four aspects of Augustine’s thought in the Confessiones that have been challenged and redefined in this dissertation: the full contextual matrix as to place, setting, and motivation for writing in Carthage North Africa 397C.E.; the genre and structural framework utilized by Augustine in framing this treatise using Plato’s Allegory of the Cave in Book VII of the Republic; “Confession” redefined as confession of sin, confession of faith and confession of truth; and the meaning or purpose for writing in regards to his scriptural philosophy of consciousness and to the redefining of Socratic ratiocination based on humanistic pagan …

A Roadmap For Urban Evolutionary Ecology, Sarah E. Diamond, Ryan A. Martin

Faculty Scholarship

Urban ecosystems are rapidly expanding throughout the world, but how urban growth affects the evolutionary ecology of species living in urban areas remains largely unknown. Urban ecology has advanced our understanding of how the development of cities and towns change environmental conditions and alter ecological processes and patterns. However, despite decades of research in urban ecology, the extent to which urbanization influences evolutionary and eco-evolutionary change has received little attention. The nascent field of urban evolutionary ecology seeks to understand how urbanization affects the evolution of populations, and how those evolutionary changes in turn influence the ecological dynamics of populations, …

November 12, 2018, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Speciation And Hybridization In Jamaican-Endemic Streamertail Hummingbirds (Trochilus Polytmus And T. Scitulus), Caroline D. Judy

LSU Doctoral Dissertations

Streamertails hummingbirds (Trochilus polytmus and T. scitulus) are recently diverged sister taxa that appear to have speciated in situ on the island of Jamaica. They are distinguished by male bill color, a secondary sexual trait that is coral red in T. polytmus and jet black in T. scitulus. They hybridize in a narrow zone where their ranges meet in eastern Jamaica. In Chapter 2, I performed a formal population survey of T. scitulus to determine the size of the population, which was unknown. I determined that the total population contains well over 100,000 individuals despite its limited …

It’S Not Quorum Without You: Bacterial Quorum Sensing In Disease States And Infection, Gregory S. O'Connor

Open Access Dissertations

Bacterial quorum sensing (QS) is a process of communication based upon small molecules that regulates gene expression, including the genes for virulence factors and biofilm formation. QS has been implicated in playing a role in many disease states. Current advances in biotechnology have allowed for the exploitation of bacteria and their QS proteins, which has led to the development of a number of technologies, including designer analytical systems. Herein, we have employed genetically engineered bacterial whole cell biosensing systems, based on the quorum sensing regulatory proteins RhlR, LasR, and LuxR, for potential biomarker detection in physiological samples. First, we have …

Habitat Segregation Between Brown Bears And Gray Wolves In A Human-Dominated Landscape, Cyril Milleret, Andrés Ordiz, Guillaume Chapron, Harry Peter Andreassen, Jonas Kindberg, Johan Månsson, Aimee Tallian, Petter Wabakken, Camilla Wikenros, Barbara Zimmermann, Jon E. Swenson, Håkan Sand

Ecology Center Publications

Identifying how sympatric species belonging to the same guild coexist is a major question of community ecology and conservation. Habitat segregation between two species might help reduce the effects of interspecific competition and apex predators are of special interest in this context, because their interactions can have consequences for lower trophic levels. However, habitat segregation between sympatric large carnivores has seldom been studied. Based on monitoring of 53 brown bears (Ursus arctos) and seven sympatric adult gray wolves (Canis lupus) equipped with GPS collars in Sweden, we analyzed the degree of interspecific segregation in habitat selection …

The Effects Of Organic And Conventional Agriculture On Bee Populations In The United States, Jordan Bicknell

University Honors Theses

Farms depend heavily on bees to provide all or most of the pollination services for food production. Conventional agriculture poses multiple threats to these valuable organisms: habitat removal for large fields, the application of synthetic pesticides and fertilizers, and the use of commercially-shipped bee colonies which can contain disease. In recent history, colony collapse disorder (CCD) has arisen in both scientific and public domains as a widespread concern for the environment and the “pollinator crisis” emerged as a result. Organic agriculture was developed in part, to mitigate the negative impacts conventional farming on the environment by prohibiting synthetic chemicals and …

Patient Experiences And Satisfaction With Homeopathic Treatment In Pune, India, Asmita R. Mhaskar

USF Tampa Graduate Theses and Dissertations

Introduction: Global populations are increasingly pursuing Complementary and Alternative Medicines (CAM) as safe, holistic options to attain health and wellness. Homeopathy is one such system of medicine whose demand is growing across the world, with maximum users in India. Yet, patient satisfaction and experiences with Homeopathy have not been addressed comprehensively in India.

Methods: A two-phase, mixed-methods study was designed to assess patient satisfaction and patient experiences with Homeopathic medicines and clinics in Pune, India. Phase I included the design and validation of a survey on Homeopathy specific experiences in English and Marathi for collecting data. Phase II employed a …

Investigation Of Acetaminophen And Caffeine Removal Using Manganese Oxides And Granular Activated Carbon In Column Experiments, Rachael E. Miera

Civil Engineering ETDs

This study was conducted to investigate the application of manganese dioxide (MnO_x(s)) and granular activated carbon (GAC) media for the removal of the acetaminophen and caffeine. Treatment of emerging micropollutants has become a concern due to their effects on environmental health. Manganese oxides can be a viable alternative for water treatment due to their abundance in the environment. Laboratory scale flow through column experiments were performed using different combinations of commercial MnO_x(s) and GAC to assess the removal of caffeine and acetaminophen, and the release of Mn due to the reductive dissolution of MnO_x(s). Results …

Teaching Evidence-Based Practices To Teachers, Jennifer M. Pena

Special Education ETDs

A convenience sample of 32 teachers (general and special education) and instructional coaches participated in professional development (PD) focused on finding, researching, and implementing evidence-based practices (EBPs) in a charter elementary/middle/high school that uses an inclusive model of special education services. Research questions addressed participants’ understandings and implementation of EBPs prior to and following the PD, as well as their reports about the PD model itself. Results indicated teachers had limited understanding of EBPs and knowledge of resources (i.e., where to find EBPs), and mixed reports of implementation prior to the PD. Throughout the study, participants reported a desire to …

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School of Art, Design and Architecture

No abstract provided.

Techniques In Medicinal Chemistry And Molecular Biology Bps 451, Joanna Burkhardt

Library Impact Statements

No abstract provided.

Relationships Between Neuronal Birthdates And Tonotopic Positions In The Mouse Cochlear Nucleus, Austin R. Shepard, Jennifer L. Scheffel, Wei-Ming Yu

Biology: Faculty Publications and Other Works

Tonotopy is a key anatomical feature of the vertebrate auditory system, but little is known about the mechanisms underlying its development. Since date of birth of a neuron correlates with tonotopic position in the cochlea, we investigated if it also correlates with tonotopic position in the cochlear nucleus (CN). In the cochlea, spiral ganglion neurons are organized in a basal to apical progression along the length of the cochlea based on birthdates, with neurons in the base (responding to high‐frequency sounds) born early around mouse embryonic day (E) 9.5–10.5, and those in the apex (responding to low‐frequency sounds) born late …

Calibration And Analysis Of A Multimodal Micro-Ct And Structured Light Imaging System For The Evaluation Of Excised Breast Tissue., David M. Mcclatchy Iii, Elizabeth J. Rizzo, Jeff Meganck, Josh Kempner, Jared Vicory, Wendy A. Wells, Keith D. Paulsen, Brian W. Pogue

Dartmouth Scholarship

A multimodal micro-computed tomography (CT) and multi-spectral structured light imaging (SLI) system is introduced and systematically analyzed to test its feasibility to aid in margin delineation during breast conserving surgery (BCS). Phantom analysis of the micro-CT yielded a signal-to-noise ratio of 34, a contrast of 1.64, and a minimum detectable resolution of 240 ?m for a 1.2?min scan. The SLI system, spanning wavelengths 490?nm to 800?nm and spatial frequencies up to 1.37 , was evaluated with aqueous tissue simulating phantoms having variations in particle size distribution, scatter density, and blood volume fraction. The reduced scattering coefficient, and phase function …

Derivatives Of A Benzoquinone Acyl Hydrazone With Activity Against Toxoplasma Gondii, A. G. Sanford, T. T. Schulze, L. P. Potluri, G. F. Watson, E. B. Darner, S. J. Zach, R. M. Hemsley, A. I. Wallick, R. C. Warner, S. A. Charman, X. Wang, J. L. Vennerstrom, P. H. Davis

Biology Faculty Publications

Toxoplasma gondii is an obligate intracellular parasite with global incidence. The acute infection, toxoplasmosis, is treatable but current regimens have poor host tolerance and no cure has been found for latent infections. This work builds upon a previous high throughput screen which identified benzoquinone acyl hydrazone (KG8) as the most promising compound; KG8 displayed potent in vitro activity against T. gondii but only marginal in vivoefficacy in a T. gondii animal model. To define the potential of this new lead compound, we now describe a baseline structure-activity relationship for this chemotype. Several derivatives displayed IC50's comparable …

Pvsripo Effect On Cancer, Vishal Jindal, Matthew Lee, Darshan Rola, Mir Saleem

Biology Faculty Articles

PVSRIPO, a variant of the poliovirus, is a revolutionary virus that demonstrates key characteristics for oncolytic virotherapy due to its ability to attack glioblastomas. The first criteria that PVSRIPO demonstrates is tumor-targeting tropism. PVSRIPO binds to nectin-like molecule 5 (Necl-5), a poliovirus receptor (PVR), found on different types of cancers such as lung cancer, colorectal cancer, and glioblastomas. This allows the virus to have a high binding affinity to tumor cells. Secondly, after modifying the poliovirus by substituting its internal ribosome entry site (IRES) with the Human Rhinovirus 2's (HRV2) IRES, the poliovirus becomes PVSRIPO, an attenuated version of the …

Biochemical And Anti-Triple Negative Metastatic Breast Tumor Cell Properties Of Psammaplins, Yu-Dong Zhou, Jun Li, Lin Du, Fakhri Mahdi, Thuy P. Le, Wei-Lun Chen, Steven M. Swanson, Kounosuke Watabe, Dale G. Nagle

Faculty and Student Publications (Open Access)

Breast tumors reprogram their cellular metabolism, nutrient uptake, and utilization-associated biochemical processes. These processes become further transformed as genetically predisposed metastatic breast tumor cells colonize specific organs. Breast tumor cells often metastasize to the brain, bone, lung and liver. Massagué and colleagues isolated organotropic subclones and established organ-specific gene signatures associated with lung-, bone-, and brain-specific metastatic triple-negative breast cancer (TNBC) MDA-MB-231 cells. Using these genetically characterized metastatic subclones specific to lung (LM4175), bone (BoM1833), and brain (BrM-2a), we evaluated marine natural products for the ability to differentially suppress metastatic breast cancer cells in a target organ-dependent manner. Psammaplin-based histone …

Sapho: A Challenging Diagnosis In A Young Woman With Recurrent Osteomyelitis, Kourtney Erickson Do, Grace Berlin Do, Yehia Y. Mishriki Md

Department of Medicine

No abstract provided.

Modeling Surface Tension Of A Two-Dimensional Droplet Using Smoothed Particle Hydrodynamics, Nowoghomwenma Noel Ehigiamusoe, Samat Maxutov, Yeaw Chu Lee

School of Engineering, Computing and Mathematics

Surface tension plays a significant role at the dynamic interface of free-surface flows especially at the microscale in capillary-dominated flows. A model for accurately predicting the formation of two-dimensional viscous droplets in vacuum or gas of negligible density and viscosity resulting from axisymmetric oscillation due to surface tension is solved using smoothed particle hydrodynamics composed of the Navier-Stokes system and appropriate interfacial conditions for the free-surface boundaries. The evolution of the droplet and its free-surface interface is tracked over time to investigate the effects of surface tension forces implemented using a modified continuous surface force method and is compared with …

The “Pedagogy Of Cruelty ” In The “Putero” Narrative, Agueda Gómezsuárez

Violence Against Women conference

This paper is focused on research regarding the sexual grammar of the narrations of prostitution customers in Spain in relation to the work of anthropologist Rita Segato, with the purpose of understanding why men pay for sex. In order to understand the causes that articulate the “putero” narrative, the discourses of prostitution customers were analyzed through semi-structured in-depth interviews, group interviews, and discussion groups. The succession of socio-sexual paradigms in our country illuminates the comprehension of this phenomenon that places Spain as the European country with the highest rate of make prostitution consumption. The stories are classified in four categories: …

Full Issue (Fall 2018)

Intersections: Critical Issues in Education

No abstract provided.

Examining Intersectionalities Among Male Faculty Of Color On The Tenure-Track, Melissa A. Martinez, Juan M. Nino, Isaac Torres

Intersections: Critical Issues in Education

This qualitative phenomenological study examined the lived experiences of 22 male assistant professors of color as they navigated the tenure-track while working in various disciplines at four-year institutions nationwide. The notion of intersectionality provided a theoretical framework to unearth how participants’ experiences were shaped. The guiding questions for the study included: 1) How do male tenure-track assistant professors of color describe their experiences in navigating academia? (2) How does intersectionality theory assist with better understanding their experiences? Findings revealed overarching themes related to how they negotiated and struggled with their various work and personal roles and responsibilities, understandings of their …

Politics, Eugenics, And Yeats's Radio Broadcasts, Melissa Dinsman

International Yeats Studies

Much has been written about the right-wing politics and eugenicist sympathies of Yeats’s late-1930s poetry in general and about On the Boiler in particular. Yeats’s focus on Ireland’s degeneration and his calls for its regeneration through cultural (and even biological methods) coincided with his dalliance with the Irish Blueshirts and his frustrations with the transformations of the Irish Free State under Éamon de Valera. However, these years also proved to be Yeats’s most active in terms of radio broadcasting, with six of his nine broadcasts made between 1937 and 1938. In this essay, I read Yeats’s broadcasts, in particular “In …

The Firece Green Fire: Vol. 9 Issue 10, Wofford College Environmental Studies Program

The Fierce Green Fire

No abstract provided.