Digital Commons Network^™

Complementary Authority And The One-Way Ratchet: Ecosystem Services Property, Regulation, And Wildlife Conservation, Kalyani Robbins

Faculty Publications

Due to the priorities of the Trump Administration, which are not a great match with those of the conservation community, we find ourselves in a period of rollbacks for all kinds of environmental regulation, including the protection of wildlife. When the federal government fails to adequately regulate, we look to other sources of authority to fill that gap. The first and most obvious place to look is to state and local governments. They are our best hope to avoid hemorrhaging vulnerable species during this presidency. Alas, looking at the realities of state wildlife conservation laws, we see the gaps remain. …

2018-2019 Undergraduate Catalog, Sacred Heart University

Graduate & Undergraduate Catalogs

No abstract provided.

Civil War: A Board Game As Pedagogy And Critique, Hugh Mccabe

Articles

This paper describes the use of a board game, Civil War, as a learning experience in the context of a course on critical theory. Civil War was created by the Educational Games Company of Lebanon and is set during the 1975-1990 Lebanese civil war. The game functions both as a pedagogical instrument, in that players learn about the situation in Lebanon while playing the game, but also as a form of critique, in that its makers are clearly using it as a means of articulating their lived experiences and challenging the dominant narratives around the conflict. We suggest that the …

2018 February Newsletter, Nova Southeastern University

Suicide and Violence Prevention Newsletters

No abstract provided.

Effects Of Tunable, 3d-Bioprinted Hydrogels On Human Brown Adipocyte Behavior And Metabolic Function, Mitchell Kuss, Jiyoung Kim, Dianjun Qi, Shaohua Wu, Yuguo Lei, Soonkyu Chung, Bin Duan

Department of Nutrition and Health Sciences: Faculty Publications

Obesity and its related health complications cause billions of dollars in healthcare costs annually in the United States, and there are yet to be safe and long-lasting anti-obesity approaches. Using brown adipose tissue (BAT) is a promising approach, as it uses fats for energy expenditure. However, the effect of the microenvironment on human thermogenic brown adipogenesis and how to generate clinically relevant sized and functioning BAT are still unknown. In our current study, we evaluated the effects of endothelial growth medium exposure on brown adipogenesis of human brown adipose progenitors (BAP). We found that pre-exposing BAP to angiogenic factors promoted …

Armms As A Versatile Platform For Intracellular Delivery Of Macromolecules, Qiyu Wang, Jiujiu Yu, Tatenda Kadungure, Joseph Beyene, Hong Zhang, Quan Lu

Department of Nutrition and Health Sciences: Faculty Publications

Majority of disease-modifying therapeutic targets are restricted to the intracellular space and are therefore not druggable using existing biologic modalities. The ability to efficiently deliver macromolecules inside target cells or tissues would greatly expand the current landscape of therapeutic targets for future generations of biologic drugs, but remains challenging. Here we report the use of extracellular vesicles, known as arrestin domain containing protein 1 [ARRDC1]-mediated microvesicles (ARMMs), for packaging and intracellular delivery of a myriad of macromolecules, including the tumor suppressor p53 protein, RNAs, and the genome-editing CRISPR-Cas9/guide RNA complex. We demonstrate selective recruitment of these macromolecules into ARMMs. When …

The Quasi-Parent Conundrum, Michael J. Higdon

Scholarly Works

Although family law is very much concerned with legal parentage and its attendant rights, children are much more concerned with maintaining relationships with those who care for them, regardless of whether that person is a legal parent or merely someone functioning as one. What happens though if the child’s legal parent attempts to banish the quasi-parent from the child’s life? Doing so can be extremely damaging to the child. Nonetheless, parents do possess a constitutional right to make decisions about how to rear their children, including who may have access to the child. Trying to strike a balance between protecting …

Photochemistry Of Polycyclic Aromatic Hydrocarbons With Environmentally Relevant Metals, John P. Haynes

Electronic Theses and Dissertations

The details of the work presented in this dissertation focus on simulated reactions in the atmosphere and water systems between persistent aromatic compounds and varying species of metals with an emphasis on iron. Bulk water suspensions of a standard soil and polycyclic aromatic hydrocarbons (PAH) were analyzed for soluble iron by inductively-coupled plasma mass spectroscopy (ICP-MS) following a 16 hour reaction period using simulated sunlight. Significant increases in soluble iron were only seen with 2-3 ring linear PAH and carboxylic acids.

A two-stage study was conducted to investigate the potential for and possible mechanisms involving the photo-oxidation of PAH into …

Native Gardens In Southern California, Center For Urban Resilience

Module 10: Garden Ecology

No abstract provided.

Book: Venture Into A New Realm Of Cross-Cultural Psychology Meditation, Mantric Poetry, And Well-Being: A Qualitative, Cross-Cultural, Cross-Disciplinary Exploration With American Secondary And Japanese Post-Secondary Adolescents, Lunthita M. Duthely, Harashita Y. Sunaoshi, Olga M. Villar-Loubet

Papers from the International Association for Cross-Cultural Psychology Conferences

Higher well-being correlates positively with multiple psychological and social outcomes, including workplace success and better academic outcomes for students. Poetry and meditation, independently, have been demonstrated in prior studies to increase well-being in a variety of contexts, including physical and mental health challenges. To our knowledge, this is the only published cross-cultural study that merged contemplative practices and poetry within the well-being paradigm, particularly among general, non-clinical adolescent populations. The purpose of this exploratory study was to examine the use of meditation and mantric poetry in a cross-cultural, educational context. The materials included The Jewels of Happiness: Inspiration and Wisdom …

Who Cares? Attitudes Of High School Students From Various Countries Towards Global And Domestic Environmental Issues, Kseniya Fomichova, Taku Misonou

Papers from the International Association for Cross-Cultural Psychology Conferences

This study focused on attitudes of 16 year-old students from six countries towards environmental issues on domestic and global scales. Male and female students from China, Guinea, Japan, Malaysia, Ukraine and Vietnam expressed their level of concern about the following in regard to their country and the world: (a) air quality, (b) drinking water quality, (c) pollution caused by atomic power plants, (d) clearing of forests, (e) extinction of plants and animals, (f) climate change and (g) global disaster. This research focused on gender and cultural variability and invariance under diverse conditions of students’ backgrounds.

The most pronounced intercultural regularity …

Comparison Of Preformed Archwires To Pretreatment Dental Casts Representing Normal Occlusions, Ezra Brown

Student Theses, Dissertations and Capstones

Introduction: Preformed nickel-titanium archwires have become an almost universal standard for archwire selection in clinical practice. However, previous studies have found that that the intercanine and intermolar widths may be altered with the use of these wires. The patient’s original arch form should not be changed. To our knowledge, previous studies have not yet assessed the intercanine and intermolar widths of preformed archwires when categorized into ovoid, tapered, and square arch forms. Therefore, the purpose of this study was to evaluate the inter-arch dimensions of commercially available preformed nickel-titanium archwires relative to normal occlusion dental arches and when compared to …

Color Removal And Treatment Of Dye And Sugar Waste Water Using Low Cost Adsorbents, Saisantosh Vamshi Harsha Madiraju

ETD Archive

This study was undertaken to determine the treatment of wastewater from dye and sugar industry for removal of color. This specific treatment consists of adsorption using low cost adsorbents and micro filtration using whatman-41 micro filters. Considerations of this treatment process is to take the samples using batch adsorption and avoid coagulation with further dilution. Numerous runs were made with the ideal waste samples prepared in the laboratory. As a first step in the study different dyes were considered using different concentrations of sugar wastewater. Samples were treated with three different low-cost adsorbents. These treated samples using low cost adsorbents …

Effect Of Feeding Regimens Of Yap Signaling, Xhuliana Fafaj, Nikkhil Velingkaar

Undergraduate Research Posters 2018

Many mammalian physiological and behavioral aspects show 24-hour circadian rhythms such as metabolism, sleep-wake cycle, body temperature and blood pressure. These 24 hour rhythms are regulated by circadian clocks, which are internal timekeeping systems located in every body cell and tissue, and synchronize these rhythms with the external environment. At the molecular level, CLOCK and BMAL1 are core clock genes involved in transcription-translation feedback loop which in turn regulate biological processes and coordinate them with daily rhythms. Circadian clock has been demonstrated to regulate cell cycle, cell proliferation and differentiation, but the mechanism in liver is not clearly known. Hippo …

Weed Communities In Urban Agriculture, Joshua Ryan

Undergraduate Research Posters 2018

Urban agriculture has been increasing all over the United States, especially in shrinking cities such as Cleveland, where increases in vacant land have brought opportunities for farming. There has also been a more interest in sustainable farming, as more people prefer locally sourced and organic food. However, like rural agriculture, urban agriculture also faces the problem of weed management, especially when growing organically eliminates some control options such as chemical means. As there is little to no research available on urban agricultural weeds, this research aims to identify and examine urban weed communities to obtain a better understanding of them, …

Simulation Of Abiotic Hurricane Effects On Lotic Meiofauna Abundance And Composition, Jamil Wilson

Undergraduate Research Posters 2018

Freshwater meiofauna are essential in our understanding of freshwater biomes. Their previous lack of attention in literature have sparked many to undergo research about their overall composition and distribution relative to many of the factors on which they depend. While more of these investigations have surfaced, few have looked at community adaptably or lack thereof when confronted with drastic changes to their environment. Therefore, this study observed what kinds of possible changes that can take place in these populations after the lingering effects of an enormous natural disaster. It is the objective of this study to identify the most influential …

Tmco1 Is A Novel Target For Cancer Chemotherapy, Ashley Przybylowicz, Ruhan Wei, Qiaoyun Zheng

Undergraduate Research Posters 2018

Transmembrane and coiled-coil domains 1 (TMCO1) is a protein of 22 KDa highly conserved in amino acid sequence among mammalian species and functions as an endoplasmic reticulum (ER) Ca2+load-activated Ca2+channel. Homozygous frameshift mutation in TMCO1 causes distinctive craniofacial dysmorphism, skeletal anomalies, and mental retardation. However, its physiological functions are largely unknown. In this study, we found that TMCO1 was co-localized with microtubules as determined by immunohistostaining and a co-sedimentation assay. Interestingly, TMCO1 was highly expressed in the invasive front of high grade lung cancer and metastatic cancer cells of clinical specimens. To further investigate the biological role of TMCO1 in …

Influence Of Stimulus Amplitude On African Clawed Frogs' Choices Between Two Stimuli, Geetha Somarouthu, Austin Shaffer, Joseph Taraba

Undergraduate Research Posters 2018

African clawed frogs locate prey using their lateral line systems to sense water movements the prey make. We’ve previously studied how the frogs choose between two stimuli; their choice is influenced by several factors including most importantly which stimulus is more rostral (i.e. more in front of them) and which is closer, which also means it arrives first with a larger amplitude. Here, we test whether stimulus amplitude affects choice. We generated surface waves by dipping two rods of different sizes into the water. Rods make waves both entering and leaving the water; both the material and diameter affect wave …

The Use Of Retinoic Acid To Promote Atrial And Ventricular “Like” Cells To Aid In Atrial Fibrillation Research, Nautica Mccully

Undergraduate Research Posters 2018

Atrial fibrillation (AF) is the irregular contraction of the atria, which are the top chambers of the heart. AF is the most common cardiac arrhythmia, affecting nearly 2.3 million people in the United States, common among people 40 and older. When AF is present the electrical signals that control this process is unbalance. Without proper diagnoses and treatment AF can be a life-treating condition. The use of human cellderived cardiomyocytes will allow the study of cells involvement in atrial fibrillation development. The addition of retinoic acid during a 30-day time course to myocytes allowed us, to investigate retinoic functions, by …

Circadian Clock Proteins Crys Are Involved In Control Of Diet Dependent Acot Expression, Marc Edwards, Allan Poe, Kuldeep Makwana

Undergraduate Research Posters 2018

Circadian clocks are evolutionarily conserved molecular timekeeping systems that generate rhythms in physiology and behavior in almost all living organisms and synchronize them with external environment. Living organisms have multiple circadian clocks which control numerous physiological functions. The light entrained circadian clock involves a transcriptional-translational feedback loop which regulates locomotor activity and metabolic processes and coordinates them with daily rhythms. The food entrainable oscillator (FEO) clock also generates near 24 hour circadian rhythmicity by driving food anticipatory behavior in mice. Mice entrained on 12:12hr light-dark cycle have been shown in previous studies to generate circadian rhythms in food anticipatory behavior, …

Roles Of H3v In Trypanosoma Brucei, Sandra Haswani

Undergraduate Research Posters 2018

African trypanosomiasis, or sleeping sickness, is caused by the parasite Trypanosoma brucei, a protozoan that affects the central nervous system. This unicellular eukaryote can be transmitted to mammals by the bite of a tsetse fly. T. brucei evades the host’s adaptive immune response by carrying out antigenic variation of its protective coat of Variant Surface Glycoprotein which allows the infection to persist and be further transmitted. T. brucei lacks the sequence-specific transcription factors found in other eukaryotes, thus chromatin structures at PTU (polycistronic transcription units) boundaries are thought to play important roles in control of gene expression. This paper focuses …

Expression And Purification Of Full-Length Recombinant Plasmodium Falciparum Pfmc-2tm Maurer’S Cleft Protein, Alberto R. Williams-Medina, Kush Addepalli

Undergraduate Research Posters 2018

Malaria caused by Plasmodium falciparum remains the most virulent form of malaria, resulting in 216 million cases and 445,000 deaths globally. Invasion of red blood cells by P. falciparum leads to the formation of membranous structures known as Maurer’s clefts (MC). Virulence markers of P. falciparum such as PfEMP1 are transported across the MC to the surface of the infected red blood cell. Insight into the formation and function of the MC will be important for the discovery of new vaccine and drug candidates. The PfMC-2TM is encoded by a multi-gene family of 13 members. PfMC- 2TM is a protein …

Comparison Of Micro-Osteoperforation And Low Level Laser Therapy (Lllt) On Accelerated Tooth Movement – An Animal Study, Abelardo Daya Attie

Student Theses, Dissertations and Capstones

Introduction: Demand for orthodontic treatment is increasing amongst patients of all ages, including adults. Typically, a comprehensive orthodontic treatment requires two to three years of active tooth movement, which may not seem desirable for adults. Orthodontic appliances can impede proper oral hygiene and increase the risk of white spot lesions and caries. Other sequel of lengthy orthodontic treatment includes external apical root resorption, increased plaque index, increased level of dental caries and subsequent gingivitis, root resorption, gingival inflammation, and bone loss. Reduction of treatment time may reduce the risk of the undesirable sequel and increase the acceptance rate of orthodontic …

Effect Of Curcumin And Bromelian On Osteogenesis Of Gingiva Derived Stem Cells, Selin Avman

Student Theses, Dissertations and Capstones

Background: Mesenchymal stem cells (MSCs) are attractive cell sources for tissue engineering application because of their ability to proliferate and differentiate into mesenchymal tissues. MSCs derived from human gingiva are readily accessible and highly proliferative with the ability to differentiate into an osteogenic lineage, making them ideal sources for tissue regeneration of craniofacial defects. While dexamethasone is a traditional inducer of osteogenic differentiation, studies have shown that its prolonged presence in culture medium may have toxic effects on osteoblasts. Many antioxidants play a vital role in promoting osteogenic differentiation and offer a potential alternative to dexamethasone. It has been demonstrated …

Effect Of Prophylactic Pastes On Surface Roughness And Gloss Of Esthetic Dental Restorative Materials, Thani Alsharari

Student Theses, Dissertations and Capstones

Objective: To evaluate the average surface roughness (Ra) and gloss (GU) of four different commonly used ceramics, four resin composites and human enamel after application of four different types of prophylactic pastes. Material and methods: A total of two hundred and forty specimens, composed of four types of ceramics and four types of resin composites were prepared to test the hypothesis. Twenty specimens were assigned to the first two ceramic groups: Lithium disilicate (LiSi2), and Feldspathic ceramic (FP). The third ceramic group, Zirconia (Zi) included one-hundred and twenty specimens divided into two groups of sixty specimens each (IPS e.max ZirCAD …

College Of Osteopathic Medicine 2018, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Assessing Beliefs, Attitudes, And Perceived Risks Of Hiv As Predictors Of Hiv Testing Behavior Among Seniors In The Coachella Valley, California, Gillian Sealy

Health Sciences Program Student Theses, Dissertations and Capstones

According to the Centers for Disease Control and Prevention (CDC) (2017), at the end of 2014, approximately 428,724 people 50 years or older were diagnosed and living with HIV in the United States. A contributing factor to the high incidence of HIV in this population is unknown HIV/AIDS serostatus (Fenton, 2007). The U.S. Department of Health and Human Services (2018), terms serostatus as the state of having or not having detectable antibodies against a specific antigen (https://aidsinfo.nih.gov/understanding-hiv-aids/glossary/1632/serostatus). Contributing to the lack of knowledge about HIV serostatus, is that those over 50 are less likely to be tested for HIV even …

Altered Ratio Of T Follicular Helper Cells To T Follicular Regulatory Cells Correlates With Autoreactive Antibody Response In Simian Immunodeficiency Virus–Infected Rhesus Macaques, Wenjin Fan, Andrew James Demers, Yanmin Wan, Qingsheng Li

Nebraska Center for Virology: Faculty Publications

Individuals with chronic HIV-1 infection have an increased prevalence of autoreactive Abs. Many of the isolated HIV broadly neutralizing Abs from these individuals are also autoreactive. However, the underlying mechanism(s) that produce these autoreactive broadly neutralizing Abs remains largely unknown. The highly regulated coordination among B cells, T follicular helper (T_FH) cells, and T follicular regulatory (T_FR) cells in germinal centers (GCs) of peripheral lymphatic tissues (LTs) is essential for defense against pathogens while also restricting autoreactive responses. We hypothesized that an altered ratio of T_FH/T_FR cells in the GC contributes to the …

Overt And Covert Attention In Infants Revealed Using Steady-State Visually Evoked Potentials, Joan Christodoulou, David S. Leland, David S. Moore

Pitzer Faculty Publications and Research

Although looking-time methods have long been used to measure infant attention and investigate aspects of cognitive development, steady-state visually evoked potential (SSVEP) measures may be more sensitive or practical in some contexts. Here, we demonstrate habituation of infants’ SSVEP amplitudes to a flickering checkerboard stimulus, and recovery of attention upon presentation of a novel checkerboard stimulus. This modulation of SSVEP amplitude was more robust than the modulation of looking time. In addition, we provide evidence of enhanced SSVEPs in response to covertly attended checkerboards flickering in peripheral visual fields, even while infants are fixating a central stimulus. These experiments provide …

Characterizing Permafrost Active Layer Dynamics And Sensitivity To Landscape Spatial Heterogeneity In Alaska, Yonghong Yi, John S. Kimball, Richard Chen, Mahta Moghaddam, Rolf H. Reichle, Umakant Mishra, Donatella Zona, Walter C. Oechel

Numerical Terradynamic Simulation Group Publications

An important feature of the Arctic is large spatial heterogeneity in active layer conditions, which is generally poorly represented by global models and can lead to large uncertainties in predicting regional ecosystem responses and climate feedbacks. In this study, we developed a spatially integrated modeling and analysis framework combining field observations, local-scale ( ∼  50 m resolution) active layer thickness (ALT) and soil moisture maps derived from low-frequency (L + P-band) airborne radar measurements, and global satellite environmental observations to investigate the ALT sensitivity to recent climate trends and landscape heterogeneity in Alaska. Modeled ALT results show good correspondence with …