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2018 January 16 - Medical Student Education Committee Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.

Diagnostic Accuracy And Prediction Increment Of Markers Of Epithelial- Mesenchymal Transition To Assess Cancer Cell Detachment From Primary Tumors, Evan L. Busch, Prabhani Kuruppumullage Don, Haitao Chu, David B. Richardson, Temitope O. Keku, David A. Eberhard, Christy L. Avery, Robert S. Sandler

Computer Science and Statistics Faculty Publications

Background

Metastases play a role in about 90% of cancer deaths. Markers of epithelial-mesenchymal transition (EMT) measured in primary tumor cancer cells might provide diagnostic information about the likelihood that cancer cells have detached from the primary tumor. Used together with established diagnostic tests of detachment—lymph node evaluation and radiologic imaging—EMT marker measurements might improve the ability of clinicians to assess the patient’s risk of metastatic disease. Translation of EMT markers to clinical use has been hampered by a lack of valid analyses of clinically-informative parameters. Here, we demonstrate a rigorous approach to estimating the sensitivity, specificity, and prediction increment …

Common Birth Control Shot Linked To Risk Of Hiv Infection, Jeff Hansen

Browse All News

No abstract provided.

Heart-Muscle Patches Created From Human Cells Improve Recovery From Heart Attacks, Jeff Hansen

Browse All News

No abstract provided.

Crow's Nest, January 16, 2018, Crow's Nest Staff

Crow's Nest

The January 16, 2018, issue of the Crow's Nest.

Resting Hormone Alterations And Injuries: Block Vs. Dup Weight-Training Among D-1 Track And Field Athletes, Keith B. Painter, G. Gregory Haff, N. Travis Triplett, Charles Stuart, Guy Hornsby, Mike W. Ramsey, Caleb D. Bazyler, Michael H. Stone

ETSU Faculty Works

Daily undulating periodization (DUP), using daily alterations in repetitions, has been advocated as a superior method of resistance training, while traditional forms of programming for periodization (Block) have been questioned. Nineteen Division I track and field athletes were assigned to either a 10-week Block or DUP training group. Year and event were controlled. Over the course of the study, there were four testing sessions, which were used to evaluate a variety of strength characteristics, including maximum isometric strength, rate of force development, and one repetition maximum (1RM). Although, performance trends favored the Block group for strength and rate of force …

The Bg News January 16, 2018, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. January 16, 2018. Volume 97-Issue 37.

Distribution Of A. Modesta, A. Julibrissin And M. Himalayana Gamble In Pir Lasura National Park, Sher Wali Khan, Nafeesa Qudsia Hanif, Madeeha Manzoor

Journal of Bioresource Management

Pir Lasura National Park (PLNP) in Azad Jammu and Kashmir, Pakistan is located in the Kotli Forest division and spans across an area of 13,900 acres. The list obtained through this study included 46 tree species of angiosperms, out of which only 3 species belong to the family Mimosaceae; A. modesta, A. julibrissin and M. himalayana gamble. A. modesta had 1.6 % constancy and belonged to class Ⅰ, A. julibrissin had 3.3% relative cover and belonged to class Ⅰ, whereas the relative vegetative cover of Mimosa himalayana gamble was too less to be tabulated. All the three species of the …

Biomedical Applications Of Hydrogels And Gumbos, Kelsey Elizabeth Mcneel

LSU Doctoral Dissertations

Sodium deoxycholate (NaDC) is a small bile salt that was used in this dissertation to produce gelation of tris(hydroxymethyl)amino-methane (TRIS) solutions above, below, and near the pKa of NaDC. These solutions respectively yielded a neutral gelator, a charged gelator, and a mixture of each. Impacts of ionic interactions on gel formation were studied in detail and showed that pH can be used to modify many hydrogel properties including sol-gel temperature, crystallinity, and mechanical strength. It was also observed that pH modification of the hydrogels affected nanoparticle formation. Nanoparticles derived from a Group of Uniform Materials Based on Organic Salts (nanoGUMBOS), …

An Invertebrate Ecosystem Engineer Under The Umbrella Of Sage-Grouse Conservation, Jason D. Carlisle, David R. Stewart, Anna D. Chalfoun

Western North American Naturalist

Conservation practitioners often rely on areas designed to protect species of greatest conservation priority to also conserve co-occurring species (i.e., the umbrella species concept). The extent to which vertebrate species may serve as suitable umbrellas for invertebrate species, however, has rarely been explored. Sage-grouse (Centrocercus spp.) have high conservation priority throughout much of the rangelands of western North America and are considered an umbrella species through which the conservation of entire rangeland ecosystems can be accomplished. Harvester ants are ecosystem engineers and play important roles in the maintenance and function of rangeland ecosystems. We compared indices of the abundance …

Music And Its Effects On Stress, Kate Pisarczyk

Music: Student Scholarship & Creative Works

While stress is a common occurrence within society, some individuals face extreme stressors that can negatively impact their physical and psychological health. College students are a subsect of society that face extreme stress on a daily basis. One of the most common forms of coping among college students is listening to music. The current research examines the effects of music listening on college student’s stress levels. Participants (N= 27) were instructed to complete an impossible mental arithmetic task while under a time limit. Afterwards, participants were given a questionnaire to rate their anxiety levels. During a five-minute recovery period, participants …

Synthetic Clock Transitions Via Continuous Dynamical Decoupling, D. Trypogeorgos, A. Valdés-Curiel, Nathan Lundblad, I. B. Spielman

All Faculty Scholarship

Decoherence of quantum systems due to uncontrolled fluctuations of the environment presents fundamental obstacles in quantum science. Clock transitions which are insensitive to such fluctuations are used to improve coherence, however, they are not present in all systems or for arbitrary system parameters. Here we create a trio of synthetic clock transitions using continuous dynamical decoupling in a spin-1 Bose-Einstein condensate in which we observe a reduction of sensitivity to magnetic-field noise of up to four orders of magnitude; this work complements the parallel work by Anderson et al. [R. P. Anderson et al., following paper, Phys. Rev. A 97, …

The Effects Of Tree Plantations And Land Use On Natural Regeneration Of Woody Plants In The Tropics: Diversity, Species Composition, Successional Dynamics, And Functional Traits, John Benjamin Longworth

LSU Doctoral Dissertations

As anthropogenic forests become more common in the tropics, there is a greater need to understand the factors that impact forest succession. I used censuses of woody plants in successional forests to study the effects of prior land use and tree plantations on species composition and richness. First, I tested the hypothesis that communities originating from different land uses were converging in species composition over time. I compared species composition using the Chao-Jaccard similarity index. I observed shifts in the dominant species during the first 30 years of succession, but not convergence of species composition in sites with different land-use …

Stochastic Estimation Of Field Management Zones Using Multi-Year Yield Data And A Hidden Markov Random Field, Alex Layton, James V. Krogmeier, Aaron Ault, Dennis Buckmaster

Department of Electrical and Computer Engineering Technical Reports

Modern precision agriculture equipment enables treating different areas of a field differently, i.e., site specific management. This results in the concept of management zones, which are a compromise between treating a field uniformly and treating every plant individually.

This work presents an algorithm for inferring the management zones for a field based on yield data from multiple years. The algorithm uses a hidden Markov random field model (HMRF) to find regions of the field which likely correspond to the same underlying yield distribution (i.e., “management zones”). These regions are assumed to be the same for each year, but their distributions …

Week Of January 16, 2018, New York Medical College

InTouch

• BioInc@NYMC Names New Director
• Bridge Funding Grants Are Announced
• La Casita de la Salud Continues to Bridge the Gap in Health Disparities
• First Patient Arrives at Touro Dental Health

Differentially-Dimensioned Furrow Formation By Zygotic Gene Expression And The Mbt, Yi Xie, J Todd Blankenship

Biological Sciences: Faculty Scholarship

Despite extensive work on the mechanisms that generate plasma membrane furrows, understanding how cells are able to dynamically regulate furrow dimensions is an unresolved question. Here, we present an in-depth characterization of furrow behaviors and their regulation in vivo during early Drosophila morphogenesis. We show that the deepening in furrow dimensions with successive nuclear cycles is largely due to the introduction of a new, rapid ingression phase (Ingression II). Blocking the midblastula transition (MBT) by suppressing zygotic transcription through pharmacological or genetic means causes the absence of Ingression II, and consequently reduces furrow dimensions. The analysis of compound chromosomes that …

Daily And Seasonal Trends Of Electricity And Water Use On Pasture-Based Automatic Milking Dairy Farms, John Shortall, Bernadette O'Brien, Roy D. Sleator, J. Upton

Department of Biological Sciences Publications

The objective of this study was to identify the major electricity and water-consuming components of a pasture-based automatic milking (AM) system and to establish the daily and seasonal consumption trends. Electricity and water meters were installed on 7 seasonal calving pasture-based AM farms across Ireland. Electricity-consuming processes and equipment that were metered for consumption included milk cooling components, air compressors, AM unit(s), auxiliary water heaters, water pumps, lights, sockets, automatic manure scrapers, and so on. On-farm direct water-consuming processes and equipment were metered and included AM unit(s), auxiliary water heaters, tubular coolers, wash-down water pumps, livestock drinking water supply, and …

Soil Savior, Sarah Schaier

UNH Today Archive

No abstract provided.

Overweight And Obesity: Correlates And Temporal Trends In Global Context, Rajesh Gautam, Amir H. Golnabi, D K. Adak, P Bharati

Department of Mathematics Faculty Scholarship and Creative Works

This work attempts to highlight the global magnitude of the obesity and examining the evolutionary perspective with focus on the correlates and temporal trend. It is based on a wide literature survey following PRISMA. The data on country wise prevalence was obtained after systematic review of over 500 articles and websites on the prevalence of obesity. A total of 301 entries/data points were found for 84 countries. Regression analysis was computed for 177 countries based on prediction made by WHO to identify the correlates. To find out the regional variation, data on height and weight of two different national surveys …

Erratum To Blahnik And Holzenthal (2017): Revision Of The Northern South American Species Of Mortoniella Ulmer, 1906 (Trichoptera: Glossosomatidae: Protoptilinae), Roger J. Blahnik, Ralph W. Holzenthal

Insecta Mundi

After publication of Blahnik and Holzenthal (2017), it was noticed that a large portion of the text had been accidentally removed from the “Phylogenetic and evolutionary comments” section during the proofing stage. The beginning of the deleted section completes the sentence on line 6 of page 129, which begins “The species included in the subgenus...”. The Insecta Mundi editorial staff apologizes for this oversight. In order to provide context for the deleted excerpt, the entire “Phylogenetic and evolutionary comments” section is reproduced here, with the deleted text reincorporated. Insecta Mundi has also released a revised version of the Blahnik and …

Curcumin Potentiates The Function Of Human Α7-Nicotinic Acetylcholine Receptors Expressed In Sh-Ep1 Cells, Eslam El Nebrisi, Lina T. Al Kury, Keun-Hang Susan Yang, Petrilla Jayaprakash, Frank Christopher Howarth, Nadine Kabbani, Murat Oz

Mathematics, Physics, and Computer Science Faculty Articles and Research

Effects of curcumin, a biologically active ingredient of turmeric, were tested on the Ca²⁺transients induced by the activation of α₇ subunit of the human nicotinic acetylcholine (α₇nACh) receptor expressed in SH-EP1 cells. Curcumin caused a significant potentiation of choline (1 mM)-induced Ca²⁺ transients with an EC₅₀ value of 133 nM. The potentiating effect of curcumin was not observed in Ca²⁺ transients induced by high K⁺ (60 mM) containing solutions or activation of α₄β₂ nACh receptors and the extent of curcumin potentiation was not altered in the presence of …

An Information Theory Approach To Hypothesis Testing In Criminological Research, Gohar A. Petrossian, Mike Maxfield

Publications and Research

Background: This research demonstrates how the Akaike information criterion (AIC) can be an alternative to null hypothesis significance testing in selecting best fitting models. It presents an example to illustrate how AIC can be used in this way.

Methods: Using data from Milwaukee, Wisconsin, we test models of place-based predictor variables on street robbery and commercial robbery. We build models to balance explanatory power and parsimony. Measures include the presence of different kinds of businesses, together with selected age groups and social disadvantage.

Results: Models including place-based measures of land use emerged as the best models among the set of …

Measuring The Regional Availability Of Forest Biomass For Biofuels And The Potential Of Ghg Reduction, Fengli Zhang, Dana M. Johnson, Jinjiang Wang, Shuhai Liu, Shimin Zhang

College of Business Publications

Forest biomass is an important resource for producing bioenergy and reducing greenhouse gas (GHG) emissions. The State of Michigan in the United States (U.S.) is one region recognized for its high potential of supplying forest biomass; however, the long-term availability of timber harvests and the associated harvest residues from this area has not been fully explored. In this study time trend analyses was employed for long term timber assessment and developed mathematical models for harvest residue estimation, as well as the implications of use for ethanol. The GHG savings potential of ethanol over gasoline was also modeled. The methods were …

Cxcr2 Is A Negative Regulator Of P21 In P53-Dependent And Independent Manner Via Akt-Mediated Mdm2 In Ovarian Cancer, Rosa Mistica C. Ignacio, Yuan-Lin Dong, Syeda M. Kabir, Hyeongjwa Choi, Eun-Sook Lee, Alicia Beeghly-Fadiel, Margaret M. Whalen, Deok-Soo Son

Chemistry Faculty Research

Ovarian cancer (OC) has the highest rate of mortality among gynecological malignancy. Chemokine receptor CXCR2 in OC is associated with poor outcomes. However, the mechanisms by which CXCR2 regulates OC proliferation remain poorly understood. We generated CXCR2-positive cells from parental p53 wild-type (WT), mutant and null OC cells, and assessed the roles of CXCR2 on proliferation of OC cells in p53-dependent and independent manner. CXCR2 promoted cell growth rate: p53WT > mutant = null cells. Nutlin-3, a p53 stabilizer, inhibited cell proliferation in p53WT cells, but had little effect in p53-mutant or null cells, indicating p53-dependence of CXCR2-mediated proliferation. CXCR2 decreased …

Netprophet 2.0: Mapping Transcription Factor Networks By Exploiting Scalable Data Resources, Yiming Kang, Hien-Haw Liow, Ezekiel J Maier, Michael R Brent

2010-2019 OA Pubs

MOTIVATION: Cells process information, in part, through transcription factor (TF) networks, which control the rates at which individual genes produce their products. A TF network map is a graph that indicates which TFs bind and directly regulate each gene. Previous work has described network mapping algorithms that rely exclusively on gene expression data and 'integrative' algorithms that exploit a wide range of data sources including chromatin immunoprecipitation sequencing (ChIP-seq) of many TFs, genome-wide chromatin marks, and binding specificities for many TFs determined in vitro. However, such resources are available only for a few major model systems and cannot be easily …

Is Cancer Progression Caused By Gradual Or Simultaneous Acquisitions Of New Chromosomes?, Mathew Bloomfield, Peter Duesberg

Natural Sciences and Mathematics | Student Professional Publications

Background

Foulds defined, “Tumor progression (as a) permanent, irreversible qualitative change in one or more of its characters” (Cancer Res. 1954). Accordingly progressions, such as metastases and acquired drug-resistance, were since found to be subspecies of cancers with conserved and numerous new chromosomes. Here we ask whether cancers acquire numerous new chromosomes gradually or simultaneously in progressions. The currently prevailing theory of Nowell (Science, 1976) holds that unexplained “genetic instability” generates “variant sublines (with) changes in chromosome number” and that “clonal” progressions arise by “stepwise selection of more aggressive sublines”. The literature, however, contains many examples of “immediate” selections of …

Gearing Up To Handle The Mosaic Nature Of Life In The Quest For Orthologs., Kristoffer Forslund, Cecile Pereira, Salvador Capella-Gutierrez, Alan Sousa Da Silva, Adrian Altenhoff, Jaime Huerta-Cepas, Matthieu Muffato, Mateus Patricio, Klaas Vandepoele, Ingo Ebersberger, Judith A. Blake, Jesualdo Tomás Fernández Breis, The Quest For Orthologs Consortium, Brigitte Boeckmann, Toni Gabaldón, Erik Sonnhammer, Christophe Dessimoz, Suzanna Lewis

Faculty Research 2018

The Quest for Orthologs (QfO) is an open collaboration framework for experts in comparative phylogenomics and related research areas who have an interest in highly accurate orthology predictions and their applications. We here report highlights and discussion points from the QfO meeting 2015 held in Barcelona. Achievements in recent years have established a basis to support developments for improved orthology prediction and to explore new approaches. Central to the QfO effort is proper benchmarking of methods and services, as well as design of standardized datasets and standardized formats to allow sharing and comparison of results. Simultaneously, analysis pipelines have been …

Lanthorn, Vol. 52, No. 34, January 15, 2018, Grand Valley State University

Volume 52, July 10, 2017 - April 23, 2018

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

Justifying A Standard Of Death, Michael Milhim

Honors Projects

There are three major positions in the legal definition of death debate: the cardio-pulmonary standard, the whole-brain standard, and the higher-brain standard. Prominent arguments for each standard appeal to a theory of human persistence. I’ll contend that these arguments fail for two reasons: the metaphysical underpinnings of the arguments are not decisive, and even if they are decisive, they may not be the right policy to enact. The later of these is more practically important than the former.

2018-01-15-Dr. Ordway, University Marketing And Communications, East Tennessee State University

Accent [newsletter]

No abstract provided.