Digital Commons Network^™

The Development Of A Community-Based Drug Intervention For Filipino Drug Users, Ma. Regina Hechanova, Arsenio S. Alianan, Mendiola Teng-Calleja, Isabel E. Melgar, Avegale Acosta, Angelique Pearl Virtue Villasanta, Kay Bunagan, Camille Yusay, Angelica Ang, Jane Flores, Nico A. Canoy, Ervina Espina, Gayle A. Gomez, Elena Samonte Hinckley, Antover P. Tuliao, Miriam P. Cue

Psychology Department Faculty Publications

This article documents the development of a community-based drug intervention for low- to mild-risk drug users who surrendered as part of the Philippine government's anti-drug campaign. It highlights the importance of developing evidence-informed drug recovery interventions that are appropriate to the Asian culture and to developing economies. Interviews and consultations with users and community stakeholders reveal the need for an intervention that would improve the drug recovery skills and life skills of users. Evidence-based interventions were adapted using McKleroy and colleagues’ (2006) Map of Adaptation Process (MAP) framework. The resulting intervention reflected the country's collectivist culture, relational values, propensity for …

The Antelope, University Of Nebraska At Kearney

The Antelope

No abstract provided.

Social Network And Dominance Hierarchy Analyses At Chimpanzee Sanctuary Northwest, Jake A. Funkhouser, Jessica A. Mayhew, John B. Mulcahy

All Faculty Scholarship for the College of the Sciences

Different aspects of sociality bear considerable weight on the individual- and group-level welfare of captive nonhuman primates. Social Network Analysis (SNA) is a useful tool for gaining a holistic understanding of the dynamic social relationships of captive primate groups. Gaining a greater understanding of captive chimpanzees through investigations of centrality, preferred and avoided relationships, dominance hierarchy, and social network diagrams can be useful in advising current management practices in sanctuaries and other captive settings. In this study, we investigated the dyadic social relationships, group-level social networks, and dominance hierarchy of seven chimpanzees (Pan troglodytes) at Chimpanzee Sanctuary Northwest. …

What Makes Us Human, Jenni Laidman

Materials from the University of Dayton Magazine Website

Science needs a new model for testing how cells react, both to things that can cure us and things that can kill us. With her half-million-dollar grant, assistant professor Kristen Comfort ’02 is developing a human model with dynamic potential.

Individual And Combined Effects Of Herbicide Tribenuron-Methyl And Fungicide Tebuconazole On Soil Earthworm Eisenia Fetida, Jiqiang Chen, Muhammad Saleem, Caixia Wang, Wenxing Liang, Qingming Zhang

Plant and Soil Sciences Faculty Publications

Earthworms are soil engineers that alter the soil bio-physical properties to favor plant growth whereas pesticides represent a significant threat to their abundance and soil health. Thus, we investigated the toxic effects of tribenuron-methyl (TBM) and tebuconazole (TEB) on the soil earthworm, Eisenia fetida. The TBM demonstrated low toxicity to E. fetida in the contact filter paper and artificial soil tests, with median lethal concentrations (LC₅₀) of 135.6 μg cm⁻² at 48 h and 511 mg kg⁻¹ on day 14, respectively. Similarly, TEB also showed low toxicity to E. fetida in the artificial …

Spectator 2018-02-14, Editors Of The Spectator

The Spectator

No abstract provided.

Promising Biomarkers Of Environmental Enteric Dysfunction: A Prospective Cohort Study In Pakistani Children., Najeeha Talat Iqbal, Kamran Sadiq, Sana Syed, Tauseefullah Akhund, Fayyaz Umrani, Sheraz Ahmed, Mohammad Yawar Yakoob, Najeeb Rehman, Shahida Qureshi, Syed Asad Ali

Department of Paediatrics and Child Health

Environmental Enteric Dysfunction (EED), a syndrome characterized by chronic gut inflammation, contributes towards stunting and poor response to enteric vaccines in children in developing countries. In this study, we evaluated major putative biomarkers of EED using growth faltering as its clinical proxy. Newborns (n = 380) were enrolled and followed till 18 months with monthly anthropometry. Biomarkersassociated with gut and systemic inflammation were assessed at 6 and 9 months. Linear mixed effects model was used to determine the associations of these biomarkers with growth faltering between birth and 18 months. Fecal myeloperoxidase (neutrophil activation marker) at 6 months [β = …

Spectrum, Volume 40, Number 3, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: SHU welcomes siblings for annual siblings weekend -- Academic mentoring program receives grant -- Former NFL player visits campus -- Anxiety isn't uncommon in college -- Wrestling hosted senior night -- Bowling team continues to excel -- Woman's lacrosse prepares for upcoming season

A Blueprint For Future Blood-Nerve Barrier And Peripheral Nerve Disease Research, Jeff Hansen

Browse All News

No abstract provided.

Repeat-Associated Non-Aug (Ran) Translation And Other Molecular Mechanisms In Fragile X Tremor Ataxia Syndrome, M. Rebecca Glineburg, Peter K. Todd, Nicolas Charlet-Berguerand, Chantal Sellier

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset inherited neurodegenerative disorder characterized by progressive intention tremor, gait ataxia and dementia associated with mild brain atrophy. The cause of FXTAS is a premutation expansion, of 55 to 200 CGG repeats localized within the 5′UTR of FMR1. These repeats are transcribed in the sense and antisense directions into mutants RNAs, which have increased expression in FXTAS. Furthermore, CGG sense and CCG antisense expanded repeats are translated into novel proteins despite their localization in putatively non-coding regions of the transcript. Here we focus on two proposed disease mechanisms for FXTAS: 1) RNA …

Scorpions Of The Horn Of Africa (Arachnida, Scorpiones). Part Xiv. Hottentotta Somalicus Sp. N. (Buthidae) From Somalia, František Kovařík

Euscorpius

Hottentotta somalicus sp. n. from Somalia is described and fully complemented with color photos. Morphologically it is similar to H. polystictus (Pocock, 1896). These two species have very narrow metasomal segments (1.63–1.73 in both sexes versus 1.31–1.61 in both sexes of other Hottentotta species from the Horn of Africa). H. polystictus and H. somalicus sp. n. occur in separate areas (Somaliland versus Somalia) and can be differentiated by color.

Cover Pages

The Great Lakes Entomologist

Cover pages for TGLE Vol. 50 Nos. 3 & 4

New Species Records For Wisconsin False Click Beetles (Coleoptera: Eucnemidae),, Robert L. Otto, Daniel K. Young

The Great Lakes Entomologist

In Wisconsin, Microrhagus opacus, Euryptychus ulkei and Fornax bicolor are recorded for the first time. Records for these three species are based on nine specimens, most of which were taken since 2008. Two specimens of M. opacus taken from a Grant County Malaise trap in the late 1970’s as part of a statewide gypsy moth parasitoid recovery project, were previously identified as Microrhagus audax. Most of the specimens reported herein were taken late in the collecting season, primarily during August. A checklist of the 20 genera and 41 species of Wisconsin Eucnemidae is also included.

Evaluative Study Of Digital Record Management System In The Hospitals In Minna Metropolis. (A Case Study Of General Hospital Minna, Niger State. Nigeria)., Akor Solomon Obotu, Uganneya Solomon A. Ph.D, Ikese Christopher Ogezi

Library Philosophy and Practice (e-journal)

ABSTRACT

The study was conducted to evaluate digital record management system in the hospitals in Minna metropolis (a case study of General Hospital Minna, Niger State). Four research questions guided the study. Survey research design was adopted. The population of the study was one hundred and twenty four (124) medical staff (Doctors, Nurses, Laboratory Technologists and Pharmacists). There was no sampling as the entire population was used for the study. A 19 items structured questionnaire was developed from the literature and used for data collection. Three experts validated the instrument. Data collected was analysed using frequency and simple percentage. The …

Attitudes And The Practice Of Documentation Of Indigenous Knowledge By The Traditional Health Practitioners In Kwara State, Nigeria., A. O. Issa Dr., Peter Olufemi Owoeye Mr.., Olubunmi O. Awoyemi Barr.

Library Philosophy and Practice (e-journal)

This paper examines the attitudes and the practice of documentation of indigenous knowledge by the traditional health practitioners (THP) in Kwara State, Nigeria. Indigenous knowledge has been playing significant roles most especially in the primary health of the people in rural areas. This important knowledge is prone to attrition due to non-documentation and the World Bank has warned that if the knowledge is not documented, it will be lost. The study adopted descriptive survey research design and utilized questionnaire to collect data for the study. 30 traditional health practitioners were purposively selected based on their experience for the study. Simple …

An Investigation On The Nexus Between Leadership Style And Job Satisfaction Of Library Staff In Private University Libraries South-West, Nigeria., Idiegbeyanose Jerome

Library Philosophy and Practice (e-journal)

Human capital is a key success factor in any organisation. Dissatisfied and unhappy staff may not perform maximally, and this could affect an organisation’s products and services. This study examined the extent to which leadership style, correlated with job satisfaction intention in private university libraries South-West, Nigeria.Survey research design was adopted. The population consisted of all the 361 library staff. Findings revealed that the level of job satisfaction of library staff was low, and that the most practice leadership style is autocratic. It also revealed a significant relationship between leadership style and job satisfaction (r = 0.028, p < 0.05); The study concluded that leadership style contributed significantly to the low level of job satisfaction. It is recommended that library management should be more democratic, payment of allowances should be put in place. This would increase the job satisfaction of the employees in private university libraries.

Assessment Of Resources In Selected Secondary School Library Media Centres In Ondo, Ondo State, Samuel O. Ogunniyi, Wasiu Olayide Lawal, Mohammed Rabiu Sheji

Library Philosophy and Practice (e-journal)

The paper assessed resources in selected secondary school library media centres in Ondo, Ondo State. Resources in the study consist of human (library staff), physical (library building, tables, chairs and shelves) and information resources (printed and digital). Adequate and relevant resources in the school library media centre will encourage students and staff to patronize and make use of the library while inadequate and irrelevant resources will discourage users from making use of the library. The study was guided by six research questions. Survey research design was adopted for the study. Six secondary schools (three boys and three girls’ schools) in …

Short-Term Thermal Acclimation Modifies The Metabolic Condition Of The Coral Holobiont, Emma M. Gibbin, Thomas Kreuger, Hollie M. Putnam, Katie L. Barrot, Julia Bodin, Ruth D. Gates, Anders Meibom

Biological Sciences Faculty Publications

The nutritional symbiosis between coral hosts and photosynthetic dinoflagellates is fundamental to the functioning of coral reefs. Rising seawater temperatures destabilize this relationship, resulting in drastic declines in world-wide coral cover. Thermal history is thought to play an important role in shaping a coral's response to subsequent thermal stress. Here, we exposed Pocillopora damicornis to two thermal acclimation regimes (ambient vs. warm) and compared the effect that acclimation had on the coral holobiont's response to a subsequent seven day heat stress event. We conducted daily physiological measurements at the holobiont level (gross photosynthesis, respiration, host protein content, symbiont density and …

The Polo-Like Kinase 1 Inhibitor Volasertib Synergistically Increases Radiation Efficacy In Glioma Stem Cells., Jianwen Dong, Soon Young Park, Nghi Nguyen, Ravesanker Ezhilarasan, Emmanuel Martinez-Ledesma, Shaofang Wu, Verlene Henry, Yuji Piao, Ningyi Tiao, David Brunell, Clifford Stephan, Roel G W Verhaak, Erik Sulman, Veerakumar Balasubramaniyan, John F De Groot

Faculty Research 2018

Background: Despite the availability of hundreds of cancer drugs, there is insufficient data on the efficacy of these drugs on the extremely heterogeneous tumor cell populations of glioblastoma (GBM).

Results: The PKIS of 357 compounds was initially evaluated in 15 different GSC lines which then led to a more focused screening of the 21 most highly active compounds in 11 unique GSC lines using HTS screening for cell viability. We further validated the HTS result with the second-generation PLK1 inhibitor volasertib as a single agent and in combination with ionizing radiation (IR).

Conclusions: Our results reinforce the potential therapeutic efficacy …

Influence Of Acute Consumption Of Caffeine Vs. Placebo Over Bia-Derived Measurements Of Body Composition: A Randomized, Double-Blind, Crossover Design, Cassie M. Williamson, Brett S. Nickerson, Emily E. Bechke, Cherilyn N. Mclester, Brian Kliszczewicz

Faculty Articles

Background Bioelectrical impedance analysis (BIA) is often used to estimate total body water (TBW), intracellular body water (ICW), extracellular body water (ECW), and body fat percentage (BF%). A common restriction for BIA analysis is abstinence from caffeine 12-h prior to testing. However, research has yet to determine whether the consumption of caffeine influences BIA testing results. The purpose of this study was to determine if the consumption of caffeine influences BIA-derived BF% and body water values in habitual caffeine users. Methods Twenty apparently healthy males (26.6 ± 4.1 years) identified as habitual caffeine consumers (≥ one 95 mg serving per …

Marine Biologist To Explore Life Cycle Diversity In Red Seaweed, Alicia Rohan

Browse All News

No abstract provided.

Heart Rate-Defined Sustained Attention In Infants At Risk For Autism, Bridgette L. Tonnsen, J. E. Richards, Jane E. Roberts

Faculty Publications

Background: Although aberrant visual attention has been identified in infants at high familial risk for autism, the developmental emergence of atypical attention remains unclear. Integrating biological measures of attention into prospective high-risk infant studies may inform more nuanced developmental trajectories, clarifying the onset and course of atypical attention and potentially advancing early screening or treatment protocols. Heart rate-defined sustained attention (HRDSA) is a well-validated biological measure of attentional engagement that, in non-clinical infant populations, provides incremental information about attentional engagement beyond looking behaviors alone. The present study aimed to examine the characteristics and clinical correlates of HRDSA in high-risk infants, …

Hypertension, Genes, And Environment: Challenges For Prevention And Risk Prediction, Richard Cooper

Faculty Publications

No abstract provided.

The Parthenon, February 13, 2018, Tom Jenkins

The Parthenon

The Parthenon, Marshall University’s student newspaper, was published by students Monday through Friday during the regular semester and weekly on Thursdays during the summer. Due to budgetary constraints, beginning with the 2016 Fall semester, the newspaper is only published two days a week. Physical issues are printed on Tuesdays and Fridays. The editorial staff is responsible for the news and the editorial content.

The Disruption And Diversification Of Higher Education Funding: Cryptocurrency For Higher Education Wealth Generation, Edward Lehner, John R. Ziegler

Publications and Research

This work conceptualizes a process for cryptocurrency to diversify traditional methods of higher education funding in the United States. Higher education funding has seemingly reached an impasse, and opinions remain divided over both which societal parties should bear the educational costs for the vast majority of Americans and how to remedy the student debt crisis. Cryptocurrency funding augments traditional revenue streams, and shifts the discussion of education costs from expenses to a more robust conversation about innovative avenues to wealth generation as a potential solution to fund the mission of American higher education. Historically, higher education has been rooted in …

Hyperspectral Measurements Of Immature Lucilia Sericata (Meigen) (Diptera: Calliphoridae) Raised On Different Food Substrates, Jodie A. Warren, T. D. Pulindu Ratnasekera, David A. Campbell, Gail S. Anderson

Faculty Research, Scholarly, and Creative Activity

Immature Lucilia sericata (Meigen) raised on beef liver, beef heart, pork liver and pork heart at a mean temperature of 20.6°C took a minimum of 20 days to complete development. Minimum development time differences within stages were observed between the meat types (pork/beef), but not the organ types (liver/heart). Daily hyperspectral measurements were conducted and a functional regression was completed to examine the main effects of meat and organ type on daily spectral measurements. The model examined post feeding larval spectral measurements of insects raised on beef liver alone, the effect of those raised on pork compared with those raised …

Microrna-223 Suppresses The Canonical Nf-Kb Pathway In Basal Keratinocytes To Dampen Neutrophilic Inflammation, Wenqing Zhou, Arpita S. Pal, Alan Yi-Hui Hsu, Theodore Gurol, Xiaoguang Zhu, Sara E. Wirbisk-Hershberger, Jennifer L. Freeman, Andrea L. Kasinski, Qing Deng

Department of Biological Sciences Faculty Publications

MicroRNA-223 is known as a myeloid-enriched anti-inflammatory microRNA that is dysregulated in numerous inflammatory conditions. Here, we report that neutrophilic inflammation (wound response) is augmented in miR-223-deficient zebrafish, due pri- marily to elevated activation of the canonical nuclear factor kB (NF-kB) pathway. NF-kB over-activation is restricted to the basal layer of the surface epithelium, although miR-223 is detected throughout the epithe- lium and in phagocytes. Not only phagocytes but also epithelial cells are involved in miR-223-medi- ated regulation of neutrophils’ wound response and NF-kB activation. Cul1a/b, Traf6, and Tab1 are iden- tified as direct targets of miR-223, and their levels …

A Novel Mir-375-Hoxb3-Cdca3/Dnmt3b Regulatory Circuitry Contributes To Leukemogenesis In Acute Myeloid Leukemia, Laixi Bi, Bin Zhou, Haiying Li, Licai He, Chunjing Wang, Zhonggai Wang, Liqing Zhu, Mengqian Chen, Shenmeng Gao

Faculty Publications

Background: Acute myeloid leukemia (AML) is a heterogeneous group of hematopoietic malignancies due to sophisticated genetic mutations and epigenetic dysregulation. MicroRNAs (miRNAs), a class of small non-coding RNAs, are important regulators of gene expression in all biological processes, including leukemogenesis. Recently, miR-375 has been reported to be a suppressive miRNA in multiple types of cancers, but its underlying anti-leukemia activity in AML is largely unknown. Methods: Quantitative reverse transcriptase PCR (qRT-PCR) was used to measure the expression of miR-375 and HOXB3 in leukemic cells and normal controls. Targets of miR-375 were confirmed by western blot and luciferase assay. Phenotypic effects …

Chapman Named N.H. Sea Grant Director, Rebecca Irelan

UNH Today Archive

No abstract provided.

Perceived Influence Of Planning And Leading On Staff Performance In Colleges Of Education Libraries In Lagos State, Nigeria, Maria Edeole Ilori Mrs, Oyintola Isiaka Amusa Dr

Library Philosophy and Practice (e-journal)

Planning and leading are important tools for the success of every organization, academic libraries inclusive. This study attempts to investigate the perceived influence of planning and leading on staff performance in colleges of education in Lagos State. The study had three research questions. The study population consisted of all the 49 library personnel professionals, Paraprofessionals and library assistants from the two colleges of education in Lagos state. A structured questionnaire was used to gather data from the respondents which were analyzed by inferential statistics. The study analysis revealed that planning has a positive influence on library staff performance and there …