Digital Commons Network^™

A Robust Statistical Estimation (Rose) Algorithm Jointly Recovers The 3d Location And Intensity Of Single Molecules Accurately And Precisely, Hesam Mazidi, Arye Nehorai, Matthew D. Lew

Electrical & Systems Engineering Publications and Presentations

In single-molecule (SM) super-resolution microscopy, the complexity of a biological structure, high molecular density, and a low signal-to-background ratio (SBR) may lead to imaging artifacts without a robust localization algorithm. Moreover, engineered point spread functions (PSFs) for 3D imaging pose difficulties due to their intricate features. We develop a Robust Statistical Estimation algorithm, called RoSE, that enables joint estimation of the 3D location and photon counts of SMs accurately and precisely using various PSFs under conditions of high molecular density and low SBR.

A Lin28b Tumor-Specific Transcript In Cancer, Weijie Guo, Zhixiang Hu, Yichao Bao, Yuchen Li, Shengli Li, Qiupeng Zheng, Dongbin Lyu, Di Chen, Tao Yu, Yan Li, Xiaodong Zhu, Jie Ding, Yingjun Zhao, Xianghuo He, Shenglin Huang

Markey Cancer Center Faculty Publications

The diversity and complexity of the cancer transcriptome may contain transcripts unique to the tumor environment. Here, we report a LIN28B variant, LIN28B-TST, which is specifically expressed in hepatocellular carcinoma (HCC) and many other cancer types. Expression of LIN28B-TST is associated with significantly poor prognosis in HCC patients. LIN28B-TST initiates from a de novo alternative transcription initiation site that harbors a strong promoter regulated by NFYA but not c-Myc. Demethylation of the LIN28B-TST promoter might be a prerequisite for its transcription and transcriptional regulation. LIN28B-TST encodes a protein isoform with additional N-terminal amino acids and is critical for cancer …

The Prospector, February 20, 2018, Utep Student Publications

The Prospector

Headline: Two Months Into 2018: 18 Gun Involved School Incidents

Heterologous Expression Of Secreted Bacterial Bpp And Hap Phytases In Plants Stimulates Arabidopsis Thaliana Growth On Phytate., Lia R. Valeeva, Chuluuntsetseg Nyamsuren, Margarita R. Sharipova, Eugene V. Shakirov

Biological Sciences Faculty Research

Phytases are specialized phosphatases capable of releasing inorganic phosphate from myo-inositol hexakisphosphate (phytate), which is highly abundant in many soils. As inorganic phosphorus reserves decrease over time in many agricultural soils, genetic manipulation of plants to enable secretion of potent phytases into the rhizosphere has been proposed as a promising approach to improve plant phosphorus nutrition. Several families of biotechnologically important phytases have been discovered and characterized, but little data are available on which phytase families can offer the most benefits toward improving plant phosphorus intake. We have developed transgenic Arabidopsis thaliana plants expressing bacterial phytases PaPhyC (HAP family …

Week Of February 20, 2018, New York Medical College

InTouch

• Biomedical Ethics Authority to Address the Class of 2018 at the 159th Commencement Exercises
• Doctor of Physical Therapy Program Hits The Mark Again...Twice
• Overseas Speech-Language Pathology Program Enriches Understanding of SLP in Other Cultures
• BioInc@NYMC Launches New Website

Host Plant Forensics And Olfactory-Based Detection In Afro-Tropical Mosquito Disease Vectors, Vincent O. Nyasembe, David P. Tchouassi, Christian W.W. Pirk, Catherine L. Sole, Baldwyn Torto

All Peer-Reviewed Publications

The global spread of vector-borne diseases remains a worrying public health threat, raising the need for development of new combat strategies for vector control. Knowledge of vector ecology can be exploited in this regard, including plant feeding; a critical resource that mosquitoes of both sexes rely on for survival and other metabolic processes. However, the identity of plant species mosquitoes feed on in nature remains largely unknown. By testing the hypothesis about selectivity in plant feeding, we employed a DNA-based approach targeting trnH-psbA and matK genes and identified host plants of field-collected Afro-tropical mosquito vectors of dengue, Rift Valley fever …

Electron Effective Mass In In0.33ga0.67n Determined By Mid- Infrared Optical Hall Effect, Nerijus Armakavicius, Vallery Stanishev, Sean Knight, Mathias Schubert, Vanya Darakchieva

Department of Electrical and Computer Engineering: Faculty Publications

Mid-infrared optical Hall effect measurements are used to determine the free charge carrier parameters of an unintentionally doped wurtzite-structure c-plane oriented In_0.33Ga_0.67N epitaxial layer. Room temperature electron effective mass parameters of m_ ¼ ð0:20560:013Þm0 andm_k ¼ ð0:20460:016Þm0 for polarization perpendicular and parallel to the c-axis, respectively,were determined. The free electron concentration was obtained as (1.760.2)_1019 cm^-3. Within our uncertainty limits, we detect no anisotropy for the electron effective mass parameter and we estimate the upper limit of the possible effective mass anisotropy as 7%. We discuss the influence of conduction band nonparabolicity on …

Scientific Issues And Controlling Strategies Of Soil Acidification Of Croplands In China, Xu Renkou, Li Jiuyu, Zhou Shiwei, Xu Minggang, Shen Renfang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Soil acidification of croplands in South of China became serious in recent decades. This not only led to the reduction in crop yields, but also enhanced uptake and accumulation of heavy metals in agricultural products, which threatened peoples' health. The main scientific issues for soil acidification control are:(1) the distribution of acidic soils in detail and the critical pH and soil Al concentration to harm various crops are not clear; (2) the prediction of soil acidification trends needs to be investigated; (3) the controlling strategies for soil acidification need to be developed. It is significant for sustainable agriculture and revitalizing …

Win-Win Nitrogen Management Practices For Improving Crop Yield And Environmental Sustainability, Yan Xiaoyuan, Xia Longlong, Ti Chaopu

Bulletin of Chinese Academy of Sciences (Chinese Version)

China is the largest nitrogen (N) fertilizer-consuming country in the world, accounting for about 33% of world total. The overuse of N fertilizer has resulted in a cascade of environmental problems without a continuous increase in crop yield. This paper briefed the N budget and N use efficiency in the cropland of China from 1980 to 2010, analyzed various N losses and their associated environmental impacts with a special focus on the discussion about how to achieve the dual goal of food security and environmental sustainability by implementing knowledge-based N management practices.

Carbon Sequestration Potential In Chinese Cropland Soils: Review, Challenge, And Research Suggestions, Zhao Yongcun, Xu Shengxiang, Wang Meiyan, Shi Xuezheng

Bulletin of Chinese Academy of Sciences (Chinese Version)

Soil organic carbon (SOC) as the core of soil fertility affects soil quality, function, and crop production, and plays a key role in global climate change. Soil resources in China are facing multiple challenges such as maintainment and improvement of food security and ecosystem functioning, and mitigation of climate change. Consequently, information and knowledge on changes in SOC in Chinese cropland are extremely important for the sustainable utilization of the soil resources in the country. This paper first reviews the common views on SOC sequestration rate and potential in Chinese cropland at the national scale, and then points out the …

Ecological Research Supports Eco-Environmental Management And Poverty Alleviation In Karst Region Of Southwest China, Wang Kelin, Chen Hongsong, Zeng Fuping, Yue Yuemin, Zhang Wei, Fu Zhiyong

Bulletin of Chinese Academy of Sciences (Chinese Version)

Huanjiang Observation and Research Station for Karst Ecosystems (HORSKE) of Chinese Academy of Sciences was founded in 2001. Since then HORSKE has been committing itself to serve the national needs for rocky desertification restoration, ecosystem services promotion, and human wellbeing improvement. HORSKE has carried on comprehensive and long-term monitoring, experiment, and demonstration to the degraded karst ecosystem. HORSKE found the dual loss characteristics for both soil and water, revealed that surface soil erosion modulus on karst hillslopes is less than 50 t/(km ²·a) and human disturbances could intensify the surface soil erosion speed. Furthermore, HORSKE clarified the effects of …

Pakistan Journal Of Pharmaceutical Sciences: A Bibliometric Assessment From 1998-2012., Zameer Hussain Baladi, Ikram Ul Haq, Manzoor Hussain, Gulnaz Elahi

Library Philosophy and Practice (e-journal)

Background: Bibliometric assessment of journal literature helps the policy makers to formulate policies regarding the related subject and to know the latest trends of publications. The pharmaceutical sciences are combination of various academics fields and technologies of pharmaceutical products related to design, action, delivery and nature of drugs. The aim of this study is to evaluate the research productivity of Pakistan Journal of Pharmaceutical Sciences (PJPS).

Research Methods: This is retrospective study on research items published in PJPS during 1998 – 2012 carried out at Libraries of King Saud bin Abdulaziz University for Health Sciences, Saudi Arabia during March …

Antarctica Marine Biology Explorers Embark On 2018 Journey, Alicia Rohan

Browse All News

No abstract provided.

Genetic And Environmental (Physical Fitness And Sedentary Activity) Interaction Effects On Cardiometabolic Risk Factors In Mexican American Children And Adolescents, Rector Arya, Vidya S. Farook, Roy G. Resendez, Srinivas Mummidi, Laura Almasy, Joanne E. Curran, Christopher P. Jenkinson, John Blangero, Ravindranath Duggirala, Vincent P. Diego

School of Medicine Publications

Knowledge on genetic and environmental (G × E) interaction effects on cardiometabolic risk factors (CMRFs) in children is limited. The purpose of this study was to examine the impact of G × E interaction effects on CMRFs in Mexican American (MA) children (n = 617, ages 6–17 years). The environments examined were sedentary activity (SA), assessed by recalls from “yesterday” (SAy) and “usually” (SAu) and physical fitness (PF) assessed by Harvard PF scores (HPFS). CMRF data included body mass index (BMI), waist circumference (WC), fat mass (FM), fasting insulin (FI), homeostasis model of assessment—insulin resistance (HOMA‐IR), high‐density lipoprotein cholesterol …

Protein Kinase D1 Regulates Subcellular Localisation And Metastatic Function Of Metastasis-Associated Protein 1, Aditya Ganju, Subhash C. Chauhan, Bilal B. Hafeez, Kyle Doxtater, Manish Tripathi, Nadeem Zafar, Murali M. Yallapu, Rakesh Kumar, Meena Jaggi

School of Medicine Publications

Background: Cancer progression and metastasis is profoundly influenced by protein kinase D1 (PKD1) and metastasis-associated protein 1 (MTA1) in addition to other pathways. However, the nature of regulatory relationship between the PKD1 and MTA1, and its resulting impact on cancer metastasis remains unknown. Here we present evidence to establish that PKD1 is an upstream regulatory kinase of MTA1.

Methods: Protein and mRNA expression of MTA1 in PKD1-overexpressing cells were determined using western blotting and reverse-transcription quantitative real-time PCR. Immunoprecipitation and proximity ligation assay (PLA) were used to determine the interaction between PKD1 and MTA1. PKD1-mediated nucleo-cytoplasmic export and polyubiquitin-dependent proteosomal …

Project Lead The Way 2018 Program Booklet, Project Lead The Way, Posters-At-The-Capitol

Posters-at-the-Capitol

Project Lead The Way 2018 Program Booklet

Posters-At-The-Capitol 2018 Program Booklet, Posters-At-The-Capitol

Posters-at-the-Capitol

Posters-at-the Capitol 2018 program booklet.

The Effects Of Soil Moisture, Soil Texture, And Host Orientation On The Ability Of Heterorhabditis Bacteriophora (Rhabditida: Heterorhabditidae) To Infect Galleria Mellonella (Lepidoptera: Pyralidae), Suzanne M. Hartley, John R. Wallace

The Great Lakes Entomologist

Abstract

Entomopathogenic nematodes (EPN) demonstrate potential as a biological control for soil dwelling insects. However, edaphic factors, such as soil moisture and texture impact the efficacy of EPN on a host. The objectives were to examine the effects of soil texture and moisture on 1) the infection rate of Galleria mellonella L. by EPN and; 2) the ability of H. bacteriophora (Poinar) to move through the soil to find a host at different orientations. Soil textures consisted of sand, a sand/silt/peat mixture, and a silt/peat mixture at 50% and 100% moisture. A general linear model was used to evaluate infection …

Lanthorn, Vol. 52, No. 44, February 19, 2018, Grand Valley State University

Volume 52, July 10, 2017 - April 23, 2018

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

Current, February 19, 2018, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.

The Tiger Vol. 112 Issue 5 2018-02-19, Clemson University

Tiger Newspapers 2018

No abstract provided.

The Tiger Election Issue 2018-02-19, Clemson University

Tiger Newspapers 2018

No abstract provided.

Mary In The News: Feb. 19, 2018, Michael Duricy

Marian Library Blog Archive

Read recent items about Mary in both Catholic and secular news. Also, see International Marian Research Institute news and updates.

The Daily Gamecock, Monday, February 19, 2018, University Of South Carolina, Office Of Student Media

February

No abstract provided.

An Effective Protocol For The Production Of Primary And Secondary Somatic Embryos In Cauliflower (Brassica Oleraceae Var. Botrytis), H Rihan, M Fuller

School of Biological and Marine Sciences

An in vitro regeneration protocol based on the use of root-derived embryogenic callus tissue was established. Three different sizes of explants were tested in order to determine the optimal size of explants for somatic embryo production. The best formation of somatic embryos was on explant size 600-1000^m achieved using 90sec duration of blending. Kinetin played an important role in somatic embryo induction, development and maturation. Embryo maturation occurred on the medium with the lowest concentration of kinetin (0.5mg L-1). Normal secondary somatic embryos (SSEs) were induced directly on hypocotyls of primary somatic when cultured on semi solid MS basal medium …

Effects Of Predispersal Insect Seed Predation On The Early Life History Stages Of A Rare Cold Sand-Desert Legume, Yi J. Han, Jerry M. Baskin, Dun Y. Tan, Carol C. Baskin, Ming Y. Wu

Biology Faculty Publications

Seed predation by insects is common in seeds of Fabaceae (legume) species with physical dormancy (PY). However, the consequences of insect seed predation on the life history of legumes with PY have been little studied. In the largest genus of seed plants, Astragalus (Fabaceae), only one study has tested the effects of insect predation on germination, and none has tested it directly on seedling survival. Thus, we tested the effects of insect predation on seed germination and seedling growth and survival of Astragalus lehmannianus, a central Asian sand-desert endemic. Under laboratory conditions, seeds lightly predated in the natural habitat …

Nominations For Outstanding Graduate Faculty Award Due By 5 P.M. March 9 (February 19, 2018), University Communications And Marketing

OHIO News Articles Archive

No abstract provided.

Mcsa Forum Minutes 02/19/2018, Morris Campus Student Association

Morris Campus Student Association

No abstract provided.

February 19, 2018 Armstrong Campus, Georgia Southern University Faculty Senate Minutes, Armstrong State University

Armstrong Faculty Senate: Minutes (Archived)

February 19, 2018 Armstrong Campus, Georgia Southern University Faculty Senate Minutes

Sarcocystis Cymruensis: Discovery In Western Hemisphere In The Brown Rat (Rattus Norvegicus) From Grenada, West Indies: Redescription, Molecular Characterization, And Transmission To Ifn-Γ Gene Knockout Mice Via Sporocysts From Experimentally Infected Domestic Cat (Felis Catus), Fernando H. Antunes Murata, Camila K. Cerqueira-Cézar, Peter C. Thompson, Keshaw Tiwari, Joseph D. Mowery, Shiv K. Verma, Benjamin M. Rosenthal, Ravindra N. Sharma, J. P. Dubey

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Rodents are intermediate hosts for many species of Sarcocystis. Little is known of Sarcocystis cymruensis that uses the Brown rat (Rattus norvegicus) as intermediate hosts and the domestic cat (Felis catus) as experimental definitive host. Here, we identified and described Sarcocystis cymruensis in naturally infected R. norvegicus from Grenada, West Indies. Rats (n = 167) were trapped in various locations in two parishes (St. George and St. David). Microscopic, thin (< 1 μm) walled, slender sarcocysts were found in 11 of 156 (7.0%) rats skeletal muscles by squash examination. A laboratory-raised cat fed naturally infected rat tissues excreted sporocysts that were infectious for interferon gamma gene knockout (KO) mice, but not to Swiss Webster outbred albino mice. All inoculated mice remained asymptomatic, and microscopic S. cymruensis-like sarcocysts were found in the muscles of KO mice euthanized on day 70, 116, and 189 post inoculation (p.i.). Sarcocysts from infected KO mice were infective for cats at day 116 but not at 70 days p.i. By transmission electron microscopy, the sarcocyst wall was Btype 1a.^ Detailed morphological description of the cyst wall, metrocytes, and bradyzoites is given for the first time. Additionally, molecular data on S. cymruensis are presented also for the first time. Molecular characterization of sarcocysts 18S rDNA and 28S rDNA, ITS-1, and cox1 loci showed the highest similarity with S. rodentifelis and S. muris. In conclusion, the present study described the natural infection of S. cymruensis in Brown rat for the first time in a Caribbean country and provided its molecular characteristics.