Digital Commons Network^™

Inhibition Of Endocytosis Suppresses The Nitric Oxide-Dependent Release Of Cl- In Retinal Amacrine Cells, Vernon K. Dunn, Evanna Gleason

Faculty Publications

© 2018 Dunn, Gleason. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Our lab has previously shown that nitric oxide (NO) can alter the synaptic response properties of amacrine cells by releasing Cl- from internal acidic compartments. This alteration in the Cl- gradient brings about a positive shift in the reversal potential of the GABA-gated current, which can convert inhibitory synapses into excitatory synapses. Recently, we have shown that the cystic fibrosis transmembrane regulator …

Pheromone-Trap Monitoring System For Pea Leaf Weevil, Sitona Lineatus: Effects Of Trap Type, Lure Type And Trap Placement Within Fields, Gadi V.P. Reddy, Govinda Shrestha, Debra A. Miller, A. Cameron Oehlschlager

Faculty Publications

The pea leaf weevil, Sitona lineatus, is an important pest of field peas and faba beans worldwide. Present sampling techniques that rely on detection of adult feeding damage are labor intensive, time consuming and require repeated sampling. Semiochemical-based pest monitoring systems could improve pea leaf weevil management. This study, which was conducted in the Golden Triangle region of Montana, tested several factors that potentially might affect capture rates of pheromone-baited traps, including trap and lure type and trap placement. Pheromone-baited pitfall and ramp traps caught significantly more adults than ground or delta traps, in all study areas. Pitfall traps baited …

Management Of Insect Pests In The Production And Storage Of Minor Pulses, Ruparao T. Gahukar, Gadi V.P. Reddy

Faculty Publications

Minor pulses are cultivated on a small scale by economically poor farming communities for subsistence food. Currently, these crops are under-utilized or neglected, although they are reasonable sources of protein and can increase food security in rural areas. Research and development is underway to improve the grain quality and increase the productivity of these crops, both of which are negatively impacted by insect pest damage. Synthetic pesticides have proven to be the most effective control agents against all pests of minor pulses which include sap sucking insects. However, considering the drawbacks of pesticide residues in the grain, environmental pollution, and …

Estimating Epidemiological Parameters Of A Stochastic Differential Model Of Hiv Dynamics Using Hierarchical Bayesian Statistics, Renee Dale, Bei Bei Guo

Faculty Publications

Current estimates of the HIV epidemic indicate a decrease in the incidence of the disease in the undiagnosed subpopulation over the past 10 years. However, a lack of access to care has not been considered when modeling the population. Populations at high risk for contracting HIV are twice as likely to lack access to reliable medical care. In this paper, we consider three contributors to the HIV population dynamics: at-risk population exhaustion, lack of access to care, and usage of anti-retroviral therapy (ART) by diagnosed individuals. An extant problem in the mathematical study of this system is deriving parameter estimates …

Natively Oxidized Amino Acid Residues In The Spinach Cytochrome B6 F Complex, Ryan M. Taylor, Larry Sallans, Laurie K. Frankel, Terry M. Bricker

Faculty Publications

© 2018, Springer Science+Business Media B.V., part of Springer Nature. The cytochrome b6f complex of oxygenic photosynthesis produces substantial levels of reactive oxygen species (ROS). It has been observed that the ROS production rate by b6f is 10–20 fold higher than that observed for the analogous respiratory cytochrome bc1 complex. The types of ROS produced (O2•−, 1O2, and, possibly, H2O2) and the site(s) of ROS production within the b6f complex have been the subject of some debate. Proposed sources of ROS have included the heme bp, PQp•− (possible sources for O2•−), the Rieske iron–sulfur cluster (possible source of O2•− and/or …

An Evaluation Of College Student Attitudes Toward Gay Adoption, Cassandra Chaney Phd, Le'brian Patrick

Faculty Publications

Given the increasing debate regarding same-sex marriage and same-sex adoption, few studies to date have examined college student attitudes regarding this topic. This qualitative study explores the sentiments of 31 college students from a large university in the southern region of the country towards gay adoption before and after viewing the documentary We Are Dad (2005). The study allowed students to provide their level of agreement or disagreement with the statements provided by respondents on a public blog site who debated both sides of this issue. In addition, students responded to the following two questions during two points in time: …

Woody Plants Optimise Stomatal Behaviour Relative To Hydraulic Risk, William R.L. Anderegg, Adam Wolf, Adriana Arango-Velez, Brendan Choat, Daniel J. Chmura, Steven Jansen, Thomas Kolb, Shan Li, Frederick C. Meinzer, Pilar Pita, Víctor Resco De Dios, John S. Sperry, Brett T. Wolfe, Stephen Pacala

Faculty Publications

Stomatal response to environmental conditions forms the backbone of all ecosystem and carbon cycle models, but is largely based on empirical relationships. Evolutionary theories of stomatal behaviour are critical for guarding against prediction errors of empirical models under future climates. Longstanding theory holds that stomata maximise fitness by acting to maintain constant marginal water use efficiency over a given time horizon, but a recent evolutionary theory proposes that stomata instead maximise carbon gain minus carbon costs/risk of hydraulic damage. Using data from 34 species that span global forest biomes, we find that the recent carbon-maximisation optimisation theory is widely supported, …

Matrix And Area Effects On The Nutritional Condition Of Understory Birds In Amazonian Rainforest Fragments, Angélica Hernández-Palma, Philip C. Stouffer

Faculty Publications

Forest fragmentation, a result of deforestation, not only decreases the amount of habitat available for wildlife, but also increases the isolation of the remaining fragments and the area of edges surrounding them. Also, deforestation often leads to the creation of a dynamic regenerating matrix where cleared land is subsequently abandoned. Here we examine the effects of fragmentation and landscape change on the nutritional condition of Amazonian rainforest birds at the Biological Dynamics of Forest Fragments Project, near Manaus, Brazil. We analyzed ptilochronology-based measurements of feather growth rate in 12 species living in fragments within a dynamic landscape over 21 years. …

What Can Mixed-Species Flock Movement Tell Us About The Value Of Amazonian Secondary Forests? Insights From Spatial Behavior, Karl Mokross, Jonathan R. Potts, Cameron L. Rutt, Philip C. Stouffer

Faculty Publications

The value of secondary forest for rain forest species remains an important question for conservation in the 21st century. Here, we describe the spatial behavior of understory mixed-species flocks in a heterogeneous landscape in central Amazonia. Understory mixed-species flocks represent a diverse, highly organized component of the rich Amazonian avifauna. We recorded movements within 26 flock home ranges in primary forest, secondary forest, interfaces between forest types, and forest fragments. We describe frequency and movement orientation in relation to forest edges, movement patterns and proportion of use between secondary and primary forest, the relation between home range sizes and vegetation …

Lawrence, Summer 2018, Lawrence University

Alumni Magazines

No abstract provided.

Association Between Asthma Control And Interleukin-17f Expression Levels In Adult Patients With Atopic Asthma, Eko E. Surachmanto, Mochammad Hatta, Andi A. Islam, Syarifuddin Wahid

Saudi Medical Journal

Objectives: To investigate the correlation between Interleukin 17 (IL-17F) and the level of asthma control. Methods: This is a cross-sectional study of 40 subjects who were diagnosed with atopic asthma. All participants were recruited from the Allergy and Immunology Clinic, Prof. R.D. Kandou General Hospital, Manado, Indonesia, between April 2015 and April 2016. Total serum IL-17F measured by using Enzyme-Linked Immunosorbent Assay methods; and mRNA IL-17F was obtained by using real-time reverse transcriptase polymerase chain reaction. Level of asthma control was quantified by using asthma control test (ACT) scoring system. The correlation between IL-17F, mRNA, and level of asthma control …

Hydrogen Sulfide Gas Detection Via Multivariate Optical Computing, Bin Dai, Christopher Michael Jones, Megan Pearl, Mickey Pelletier, Michael L. Myrick

Faculty Publications

Hydrogen-sulfide gas is a toxic, colorless gas with a pungent odor that occurs naturally as a decomposition by-product. It is critical to monitor the concentration of hydrogen sulfide. Multivariate optical computing (MOC) is a method that can monitor analytes while minimizing responses to interferences. MOC is a technique by which an analogue calculation is performed entirely in the optical domain, which simplifies instrument design, prevents the drift of a calibration, and increases the strength and durability of spectroscopic instrumentation against physical perturbation when used for chemical detection and identification. This paper discusses the detection of hydrogen-sulfide gas in the ultraviolet …

Low Carbon Land Use: Paris, Pittsburgh, And The Ipcc, John R. Nolon

University of Arkansas at Little Rock Law Review

No abstract provided.

Principles Of Nutrition (Ghc), Lisa Jellum, Jason Hitzeman, Mark Knauss, Sharryse Henderson, Tom Harnden, Cynthia Elsberry, Greg Ford

Nursing and Health Sciences Grants Collections

This Grants Collection for Principles of Nutrition was created under a Round Nine ALG Textbook Transformation Grant.

Affordable Learning Georgia Grants Collections are intended to provide faculty with the frameworks to quickly implement or revise the same materials as a Textbook Transformation Grants team, along with the aims and lessons learned from project teams during the implementation process.

Documents are in .pdf format, with a separate .docx (Word) version available for download. Each collection contains the following materials:

• Linked Syllabus
• Initial Proposal
• Final Report

The Global Person: Pig-Human Embryos, Personhood, And Precision Medicine, Yvonne Cripps

Indiana Journal of Global Legal Studies

Chimeras, in the form of pig-human embryos engineered by CRISPR-Cas9 and other biotechnologies, have been created as potential sources of organs for transplantation. Against that background, and in an era of "precision medicine," this Article examines the concept of the global genetically modified person and asks whether humanness and personhood are being eroded, or finding new boundaries in intellectual property and constitutional law.

Three New Metrics For Patent Examiner Activity: Office Actions Per Grant Ratio (Ogr), Office Actions Per Disposal Ratio (Odr), And Grant To Examiner Ratio (Ger), Shine Tu

Law Faculty Scholarship

The current metric for examiner prosecution activity is allowance rate, which is calculated by dividing the total number of allowances by the sum of the allowances and abandonments (allowance rate = total allowance/(total allowances total abandonments)). Importantly, however, allowance rates do not consider an examiner’s pending docket. Specifically, allowance rates do not fully capture if the examiner is simply writing office actions thereby prolonging prosecution or allowing cases. This study rectifies this failure by creating and analyzing a dataset that captures every active examiner’s current docket. Calculating the Office Action per Grant Ratio (OGR = Total # of Office Actions/Total …

Association Tests For Genetic Effect And Its Interaction With Environmental Factors, Zhengyang Zhou

Statistical Science Theses and Dissertations

My research is in the area of statistical genetics, and it contains three projects: (1) Differentiating the Cochran-Armitage (CA) trend test and Pearson’s chi-square test: location and dispersion; (2) Decomposing Pearson’s chi-square test: a linear regression and its departure from linearity; (3) Testing nonlinear gene-environment (GxE) interaction through varying coefficient and linear mixed models.

(1) In genetic case-control association studies, a standard practice is to perform the CA trend test with 1 degree-of-freedom (df) under the assumption of an additive model. However, when the true genetic model is recessive or near recessive, it is outperformed by Pearson’s chi-square test with …

Combined Effects Of Deepwater Horizon Crude Oil And Environmental Stressors On Fundulus Grandis Embryos, Maria L. Rodgers, Elizabeth R. Jones, Christopher Klinkhamer, Cecon T. Mahapatra, Jennifer Serafin, Thijs Bosker, Chris Perkins, Robert J. Griffitt, Sylvain De Guise, Maria S. Sepúlveda

Faculty Publications

In the present study, we examined how sensitivity to oil changes in combination with environmental stressors in Fundulus grandis embryos. We exposed embryos (fertilization) to a range of high‐energy water accommodated fraction (HEWAF) concentrations (0–50 parts per billion [ppb] total polycyclic aromatic hydrocarbons [PAHs]) made from Macondo crude oil in conjunction with various environmental conditions (temperature: 20 and 30 °C; salinity: 3, 7, and 30 practical salinity units [PSU]; and dissolved oxygen: 2 and 6 mg/L). Endpoints included mortality, hatching rates, and expression of cytochrome p450 1a and 1c (cyp1a, cyp1c) in hatched larvae. There was 100% …

Gekko Optimization Suite, Logan Beal, Daniel Hill, Ronald Abraham Martin, John Hedengren

Faculty Publications

This paper introduces GEKKO as an optimization suite for Python. GEKKO specializes in dynamic optimization problems for mixed-integer, nonlinear, and differential algebraic equations (DAE) problems. By blending the approaches of typical algebraic modeling languages (AML) and optimal control packages, GEKKO greatly facilitates the development and application of tools such as nonlinear model predicative control (NMPC), real-time optimization (RTO), moving horizon estimation (MHE), and dynamic simulation. GEKKO is an object-oriented Python library that offers model construction, analysis tools, and visualization of simulation and optimization. In a single package, GEKKO provides model reduction, an object-oriented library for data reconciliation/model predictive control, and …

Shinykgode: An Interactive Application For Ode Parameter Inference Using Gradient Matching, J Wandy, M Niu, D Giurghita, Et Al

School of Engineering, Computing and Mathematics

MOTIVATION: Mathematical modelling based on ordinary differential equations (ODEs) is widely used to describe the dynamics of biological systems, particularly in systems and pathway biology. Often the kinetic parameters of these ODE systems are unknown and have to be inferred from the data. Approximate parameter inference methods based on gradient matching (which do not require performing computationally expensive numerical integration of the ODEs) have been getting popular in recent years, but many implementations are difficult to run without expert knowledge. Here, we introduce ShinyKGode, an interactive web application to perform fast parameter inference on ODEs using gradient matching. RESULTS: ShinyKGode …

The Aspergillus Nidulans Pyruvate Dehydrogenase Kinases Are Essential To Integrate Carbon Source Metabolism, Laure Nicolas Annick Ries, De Assis L José, Fernando José Santos Rodrigues, Camila Caldana, Marina Campos Rocha, Iran Malavazi, Özgür Bayram, Gustavo H. Goldman

School of Biomedical Sciences

The pyruvate dehydrogenase complex (PDH), that converts pyruvate to acetyl-coA, is regulated by pyruvate dehydrogenase kinases (PDHK) and phosphatases (PDHP) that have been shown to be important for morphology, pathogenicity and carbon source utilization in different fungal species. The aim of this study was to investigate the role played by the three PDHKs PkpA, PkpB and PkpC in carbon source utilization in the reference filamentous fungus Aspergillus nidulans, in order to unravel regulatory mechanisms which could prove useful for fungal biotechnological and biomedical applications. PkpA and PkpB were shown to be mitochondrial whereas PkpC localized to the mitochondria in a …

Citizen Scientists Monitoring The Establishment And Expansion Of Pterois Miles (Bennett, 1828) In The Aegean Sea, Greece, I Giovos, P Kleitou, V Paravas, Et Al

School of Biological and Marine Sciences

The introduction of the lionfish in the western Atlantic has been considered as one of the world's most detrimental invasions. However, in the Mediterranean Sea, the devil firefish Pterois miles (Bennett, 1828) long after its first record in 1991, has only recently shown a rapid expansion. Citizen scientists have played a significant role in reporting the presence and monitoring the expansion of several invasive species around the world. In 2016 the environmental non- governmental Greek organisation "iSea", initiated the citizen science project "Is it alien to you…Share it", for the monitoring of alien species in the Greek waters. Between May …

“Compassion And Benignytee”: A Reassessment Of The Relationship Between Canacee And The Falcon In Chaucer’S “Squire’S Tale”, Melissa Ridley Elmes

Medieval Feminist Forum: A Journal of Gender and Sexuality

Among its many elements, Chaucer’s “Squire’s Tale” includes an emotionally-charged dialogue between two aristocratic female figures: the human daughter of a king, Canacee, and the wounded falcon she meets in the wood. Scholars have debated the nature of this relationship in interspecial, gendered, and specifically feminist and ecofeminist terms. This essay provides a brief retrospective on some of the most recent scholarship examining their relationship—van Dyke (2005); Kordecki (2011); Crane (2012); and Schotland (2012 and 2015)—leading into a reassessment in two parts: first, that the affinity- and experience-driven bond these female figures develop supports a reading of this scene that …

Belligerent Mothers And The Power Of Feminine Speech In _The Owl And The Nightingale_, Wendy A. Matlock

Medieval Feminist Forum: A Journal of Gender and Sexuality

The Middle English poem The Owl and the Nightingale famously records the dispute between a hostile Nightingale and a bellicose Owl. Within that dialogue the birds reproduce themselves in word and egg, in rhetoric and body. Their digressions on bodies and scatology and on childbearing and childrearing become fertilizer that expands maternal authority into public, intellectual discourse. In addition to calling forth their own communicative powers, both characters aggressively recount narratives best known from the work of Marie de France, a voice feminist scholars have successfully restored to the canon, to condemn their foe. In this light, I argue, The …

Gender In The Context Of Same-Sex Divorce And Relationship Dissolution, Suzanne A. Kim, Edward D. Stein

Articles

This article identifies ways that judges, lawyers, researchers, and policy makers may attend to the role of gender and gender dynamics facing same-sex couples upon divorce or other relationship dissolution. When same-sex couples marry, the legal system and society at large may project conceptions of gender onto same-sex couples, often in a manner that conflicts with couples’ intentions and practices. Gender and gender dynamics may affect the bases for dissolution, the financial aspects of dissolution, and the determination of child custody. The article also suggests directions for future research on the impact of gender on the dissolution of same-sex relationships.

A Survey Of Matrix Completion Methods For Recommendation Systems, Andy Ramlatchan, Mengyun Yang, Quan Liu, Min Li, Jianxin Wang, Yaohang Li

Computer Science Faculty Publications

In recent years, the recommendation systems have become increasingly popular and have been used in a broad variety of applications. Here, we investigate the matrix completion techniques for the recommendation systems that are based on collaborative filtering. The collaborative filtering problem can be viewed as predicting the favorability of a user with respect to new items of commodities. When a rating matrix is constructed with users as rows, items as columns, and entries as ratings, the collaborative filtering problem can then be modeled as a matrix completion problem by filling out the unknown elements in the rating matrix. This article …

Motley Crew: Collaboration Across An Academic Library To Revive An Orphaned Collection, Amy Jankowski, Anne Schultz, Laura Soito

University Libraries & Learning Sciences Faculty and Staff Publications

It can be difficult to find time and motivation to effectively address collection management for materials in specialized areas that fall outside the primary scope of one’s usual responsibilities. The pressure of crowded shelves in the authors’ largest library and the associated difficulties of helping users locate materials led a team of faculty librarians and staff to evaluate and consolidate an “orphaned collection” of books in health and medicine call numbers. The authors describe how a project team established a data-informed evaluation and weeding process that minimized affective decision-making and considered the nuances of collection management between disciplines.

Effects Of Mowing And Tebuthiuron On The Nutritional Quality Of Wyoming Big Sagebrush, Kurt T. Smith, Jennifer S. Forbey, Jeffrey L. Black

Biology Faculty Publications and Presentations

Wyoming big sagebrush (Artemisia tridentata Nutt. ssp. wyomingensis Beetle & Young) is the most abundant and widely distributed subspecies of big sagebrush and has been treated through chemical application, mechanical treatments, and prescribed burning in efforts thought to improve habitat conditions for species such as greater sage-grouse (Centrocercus urophasianus) and mule deer (Odocoileus hemionus). Although the response of structural attributes of sagebrush communities to treatments is well understood, there is a need to identify how treatments influence the quality of sagebrush as winter food for wildlife. Our purpose was to identify how mowing and tebuthiuron …

Applying Social Work Values To The Care And Treatment Of Intersex People, Michelle Anklan, Jeffrey Matejcek, Lorelei Tinaglia

Master of Social Work Student Policy Advocacy Briefs

The "problem" of intersex conditions is not due to intersex variations themselves, rather contemporary society's binary understanding of sex. The term “intersex” refers to individuals born with “anatomies that are considered ‘atypical’ for either male or female bodies.” There are over 40 variations of sex development that can be referred to as “intersex”, which makes conforming to the binary (i.e. male/female) system of gender problematic. The United Nations Human Rights Office of the High Commissioner affirms that, "being intersex relates to biological sex characteristics, and is distinct from a person's sexual orientation or gender identity." Dominant medical procedure throughout the …

Greater Wealth Inequality, Less Polygyny: Rethinking The Polygyny Threshold Model, John Ziker

Anthropology Faculty Publications and Presentations

Monogamy appears to have become the predominant human mating system with the emergence of highly unequal agricultural populations that replaced relatively egalitarian horticultural populations, challenging the conventional idea—based on the polygyny threshold model—that polygyny should be positively associated with wealth inequality. To address this polygyny paradox, we generalize the standard polygyny threshold model to a mutual mate choice model predicting the fraction of women married polygynously. We then demonstrate two conditions that are jointly sufficient to make monogamy the predominant marriage form, even in highly unequal societies. We assess if these conditions are satisfied using individual-level data from 29 human …