Digital Commons Network^™

Correlation Of Aqueous Solubility And Anti-Cancer Activity Of Novel Triazolium And Imidazolium Salts, Jared J. Bies

Theses and Dissertations

Novel triazolium, imidazolium, and benzimidazolium salts are known to possess anti-cancer properties and have potential as cancer therapeutics. This thesis describes the aqueous solubility and the differential activity of N,AT-bis-substituted-l,2,4-triazolium bromide salts and N/N'-bis(naphthylmethyl)imidazolium bromide salts against MDA-MB-468 breast cancer cells and PC-3 prostate carcinomas. Using a microscale technique, the partition coefficient (log P) of each salt was determined. The log P value was explored to determine the bioavailability of each derivative.

The Study Of The Degradation Of Hexabromocyclododecane In A Heterogeneous System Containing Fe(Ii) Adsorbed To The Iron Oxide Hematite., Kristian K. Roopnarine

Dissertations and Theses

The reaction of hexabromocyclododecane (HBCDD), a widely used brominated flame retardant, was studied in a heterogenous mixture containing reactive Fe(II) adsorbed to the iron oxide hematite. The adsorbed Fe(II)/iron oxide system has shown to be a potent reductant in the transformation of organic contaminants with relatively water soluble organic contaminants. There currently aren’t many studies involving hydrophobic organic contaminants, such as HBCDD, in this reducing Fe(II)/iron oxide system. The results indicate that across the pHs 6.86, 6.95, 7.15 and 7.35 γ and β-HBCDD are degraded within a couple days. The pseudo-first order rate constants at pH 6.95 are 0.049 hr …

Rmdc Edition 2018

Metro Denver Dental Society Articulator Magazine

The MDDS Articulator magazine has been serving as the voice for Denver's dental community for over 100 years.

Distributed to approximately 2,000 dental professionals quarterly, the Articulator features local news, industry trends, practice management guidance, data-driven research and more. The award-winning publication is available to member dentists in both print and digital forms.

Issues include cover and feature articles alongside regular columns with regional news impacting the Metro Denver membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

High Sensitivity Optical Fiber Interferometric Sensors, Dejun Liu

Doctoral

Optical fiber interferometers have been widely employed and investigated for monitoring the changes in both physical and chemical parameters, with the advantages of compact size, light weight, immunity to electromagnetic interference, high sensitivity, capability to work in harsh environments and remote operation capabilities. Among the different kinds of fiber sensors based on interferometry, singlemode-multimode-singlemode (SMS) structures has attracted considerable interest due to their inherent advantages of high sensitivity, ease of fabrication and interconnection to other fiber systems and low cost. However, the challenge is that the sensitivity of the traditional SMS based fiber structure is not sufficient in some cases, …

Navigating Roadblocks: First-Year Writing Challenges Through The Lens Of The Acrl Framework, Glenda M. Insua, Catherine Lantz, Annie Armstrong

Communications in Information Literacy

Effectively integrating the ACRL Framework for Information Literacy into existing instructional models requires that librarians first understand the host of challenges that many first-year students encounter when conducting research for the first time. This study employs qualitative analysis of semi-structured student interviews to explore how students conceive of and pursue the research process, and how they try to mitigate—and in some cases surmount—the roadblocks they encounter. Although students reported several difficulties, three main roadblocks arose: challenges with understanding academic articles, challenges with the topic/theme of the course, and challenges with navigating the physical space of the library. Our findings demonstrate …

Bilingualism Positively Predicts Mathematical Competence: Evidence From Two Large-Scale Studies, Andree Hartanto, Hwajin Yang, Sujin Yang

Research Collection School of Social Sciences

Although little is known about the link between bilingualism and mathematical achievement in children, the established link between executive functions (EFs) and mathematical achievement suggests that bilingualism—which has been shown to affect EFs—may positively predict math skills. Drawing on two large-scale datasets collected in the US—the Multi-State Study of Pre-Kindergarten and the State-Wide Early Education Programs (Study 1) and the Early Childhood Longitudinal Study (Study 2)—we examined the relation between bilingualism and mathematical achievement among preschoolers, kindergarteners, and first-grade students (ages 4–7), while controlling for key covariates of (a) demographic variables, such as age, gender, race/ethnicity, and socioeconomic status; and …

ฟังข่าวรอบบ้าน: ความคืบหน้าของการปฏิรูปประเทศด้านทรัพยากรธรรมชาติและสิ่งแวดล้อม, ทรงกฤษณ์ ประภักดี

Thai Environment

No abstract provided.

แนวทางในการพัฒนาอุทยานแห่งชาติเขาใหญ่ให้เป็นแหล่งท่องเที่ยวแบบยั่งยืน, ณัฏฐ์นันท์ คำทอง, เพชรรัตน์ โล้วิชากรติกุล

Thai Environment

จากการศึกษาแนวทางในการพัฒนาอุทยานแห่งชาติเขาใหญ่ให้เป็นแหล่งท่องเที่ยวแบบยั่งยืน มีวัตถุประสงค์ (1) ศึกษาถึงปัญหาและอุปสรรคเพื่อให้ทราบถึงแนวทางการพัฒนาอุทยานแห่งชาติเขาใหญ่ให้เป็นแหล่งท่องเที่ยวแบบยั่งยืน (2) เพื่อศึกษาถึงทัศนคติเกี่ยวกับการให้คุณค่าในพื้นที่และการเห็นความสำคัญต่อการอนุรักษ์ (3) เพื่อให้ทุกคนตระหนักถึงความสำคัญของการท่องเที่ยวแบบยั่งยืนต่อทรัพยากรการท่องเที่ยว การวิจัยครั้งนี้เป็นการวิจัยเชิงคุณภาพโดยเก็บข้อมูลจากการสัมภาษณ์เชิงลึกกับกลุ่มผู้ให้ข้อมูลหลัก คือ เจ้าหน้าที่ผู้ดูแลอุทยานฯ ที่เกี่ยวข้อง หน่วยงานภาครัฐและเอกชนที่เกี่ยวข้อง และผู้ให้ข้อมูลรอง คือ สถานประกอบการ และนักท่องเที่ยว จำนวนทั้งสิ้น 28 คน รวมถึงการสังเกตแบบไม่มีส่วนร่วม โดยนำข้อมูลที่ได้มาวิเคราะห์และสรุปผล เพื่อหาแนวทางในการแก้ไข จากการศึกษาพบว่า (1) อุทยานฯ มีปัญหาที่ยังไม่สามารถแก้ไขได้คือ ปัญหาลักลอบตัดไม้พะยูง ปัญหาสัตว์ป่าอันเนื่องมาจากพฤติกรรมของมนุษย์ และพฤติกรรมของผู้ที่มาเยือนอุทยานฯ เขาใหญ่ (2) ด้านทัศนคติพบว่า ผู้ให้ข้อมูลหลักเล็งเห็นความสำคัญต่อการอนุรักษ์ทรัพยากรธรรมชาติ เนื่องจากต้องดูแลผืนป่าสงวนที่มีผลต่อความมั่นคงระดับชาติ สำหรับผู้ให้ข้อมูลรองจะให้ความสำคัญกับการอนุรักษ์ทรัพยากรในพื้นที่เพราะเป็นแหล่งอาศัยและใช้ทำมาหากินจึงก่อให้เกิดความหวงแหน สำหรับนักท่องเที่ยวมากกว่าครึ่งที่ได้สัมภาษณ์จะเล็งเห็นความสำคัญและคุณค่าของพื้นที่ (3) ด้านการให้ความสำคัญต่อการท่องเที่ยวแบบยั่งยืนพบว่า ผู้ให้ข้อมูลหลักจะให้ความสำคัญเป็นอย่างยิ่ง เนื่องจากมีหน้าที่ในการอนุรักษ์และปกป้องอุทยานฯ ในฐานะที่เป็นมรดกโลก สำหรับสถานประกอบการที่อยู่รอบอุทยานฯ จะให้ความสำคัญกับการท่องเที่ยวแบบยั่งยืนเพราะจำเป็นต้องพึ่งพาอุทยานฯ ในการประกอบอาชีพ และสำหรับนักท่องเที่ยว จะให้ความสำคัญต่อการท่องเที่ยวแบบยั่งยืนเฉลี่ยอยู่ในระดับปานกลาง

การใช้ประโยชน์จากซากแผงวงจรอิเล็คทรอนิกส์ (ส่วนอโลหะ) และผลกระทบต่อสิ่งแวดล้อม, มงคลชัย อัศวดิษฐเลิศ, เจริศา จำปา

Thai Environment

No abstract provided.

The Bookstore Is For T-Shirts: Cooperatively Marketing The Library's Ebooks As Textbooks, Krystie Wilfong, Kelly Robinson, Maura Diamond

ILS Scholarship

Textbook affordability has become a key concern for faculty, publishers, and librarians. A librarian-publisher team will provide a toolkit for librarians interested in identifying ebooks within their collection that may be used as affordable course texts, as well as methods for working with publishers and faculty in collaborative marketing.

Preliminary Multivariate Comparison Of Coral Assemblages On Carbonate Banks In The Western Gulf Of Mexico, Rebekah E. Rodriguez, Erin E. Easton, Thomas C. Shirley, John W. Tunnell, David Hicks

School of Earth, Environmental, & Marine Sciences Faculty Publications

Hermatypic corals flourished on reefs in the Gulf of Mexico (GOM) in the late Pleistocene and early Holocene. Today, many of these relict reefs are mesophotic banks that have unique coral assemblages and provide critical habitat; however, the South Texas Banks (STB) lack quantitative surveys. Therefore, we used a remotely operated vehicle to conduct quantitative surveys of 5 banks: Baker, Aransas, Dream, Blackfish Ridge, and Harte. Coral communities, based on estimated coral densities (colonies/m2), significantly differed among banks for terraces, slopes, and overall (combined terrace and slope) communities for most banks examined. Within banks, terrace and slope communities significantly differed …

First Record Of The Yellowfin Soldierfish, Myripristis Chryseresjordan & Evermann, 1903, In The Easter Island Ecoregion, Erin E. Easton, Javier Sellanes, Matthias Gorny

School of Earth, Environmental, & Marine Sciences Faculty Publications

Myripristis chryseres Jordan & Evermann, 1903, is recorded for the first time in the Easter Island Ecoregion. Two specimens were observed swimming along a rock cliff and entering a cavern at ∼163 m depth near the peak of Pukao seamount, located ∼85 km (46 nm) west of Easter Island. This report expands the geographic range of M. chryseres eastward by ∼3,800 km and is the first report of the species for the eastern Pacific. It is unclear whether this new record is indicative of a relatively recent range expansion or a lack of visual surveys in the region, which …

Noncommutative Reality-Based Algebras Of Rank 6, Allen Herman, Mikhael Muzychuk, Bangteng Xu

EKU Faculty and Staff Scholarship

We show that noncommutative standard reality-based algebras (RBAs) of dimension 6 are determined up to exact isomorphism by their character tables. We show that the possible character tables of these RBAs are determined by seven real numbers, the first four of which are positive and the remaining three real numbers can be arbitrarily chosen up to a single exception. We show how to obtain a concrete matrix realization of the elements of the RBA-basis from the character table. Using a computer implementation, we give a list of all noncommutative integral table algebras of rank 6 with orders up to 150. …

Tuhualite In A Peralkaline Rhyolitic Ignimbrite From Pantelleria, Italy, Boguslaw Baginski, Ray Macdonald, John C. White, Lidia Jezak

EKU Faculty and Staff Scholarship

An occurrence of the rare mineral tuhualite (NaFe3+Fe2+Si6O15) is reported in a peralkaline rhyolitic ignimbrite from the 11 island of Pantelleria, Italy. The mineral formed during devitrification of glassy fiamme and varies in form from anhedral plates to 12 perfect euhedral in open vesicles. There is significant replacement of Fe2+ by Mn (FMQ in the presence of a 14 hydrous fluid.

Study Of Gas Production From Shale Reservoirs With Multi-Stage Hydraulic Fracturing Horizontal Well Considering Multiple Transport Mechanisms, Chaohua Guo, Mingzhen Wei, Hong Liu

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Development of unconventional shale gas reservoirs (SGRs) has been boosted by the advancements in two key technologies: horizontal drilling and multi-stage hydraulic fracturing. A large number of multi-stage fractured horizontal wells (MsFHW) have been drilled to enhance reservoir production performance. Gas flow in SGRs is a multi-mechanism process, including: desorption, diffusion, and non-Darcy flow. The productivity of the SGRs with MsFHW is influenced by both reservoir conditions and hydraulic fracture properties. However, rare simulation work has been conducted for multi-stage hydraulic fractured SGRs. Most of them use well testing methods, which have too many unrealistic simplifications and assumptions. Also, no …

Development Of Photocatalysts Supported On Graphitic Carbon Nitride For The Degradation Of Organic Water Pollutants, Atanu Giri

Theses and Dissertations

Graphitic carbon nitride (g-C₃N₄) heterojunction composites with the semiconducting metal oxides, CeO₂, ZnO and TiO₂ are prepared in situ by co-calcination of the precursor materials or by a solvothermal method. The structural, morphological and the optical properties of the prepared materials are studied using various microscopy and spectroscopy techniques. The synthesized composite materials, CeO₂/g-C₃N₄, ZnO/g-C₃N₄ and TiO₂/g-C₃N₄ are more efficient in the photocatalytic degradation of the water pollutants indigo carmine (IC) and atrazine than the pure metal oxide, g-C …

Developing A Cyberterrorism Policy: Incorporating Individual Values, Osama Bassam J. Rabie

Theses and Dissertations

Preventing cyberterrorism is becoming a necessity for individuals, organizations, and governments. However, current policies focus on technical and managerial aspects without asking for experts and non-experts values and preferences for preventing cyberterrorism. This study employs value focused thinking and public value forum to bare strategic measures and alternatives for complex policy decisions for preventing cyberterrorism. The strategic measures and alternatives are per socio-technical process.

Motion-Induced Artifact Mitigation And Image Enhancement Strategies For Four-Dimensional Fan-Beam And Cone-Beam Computed Tomography, Matthew J. Riblett

Theses and Dissertations

Four dimensional imaging has become part of the standard of care for diagnosing and treating non-small cell lung cancer. In radiotherapy applications 4D fan-beam computed tomography (4D-CT) and 4D cone-beam computed tomography (4D-CBCT) are two advanced imaging modalities that afford clinical practitioners knowledge of the underlying kinematics and structural dynamics of diseased tissues and provide insight into the effects of regular organ motion and the nature of tissue deformation over time. While these imaging techniques can facilitate the use of more targeted radiotherapies, issues surrounding image quality and accuracy currently limit the utility of these images clinically.

The purpose of …

Differences In Spatial Visualization Ability And Vividness Of Spatial Imagery Between People With And Without Aphantasia, Anita Crowder

Theses and Dissertations

Mathematics education researchers have examined the relationship between visualization and mathematics for decades (e.g., Arcavi, 2003; Bishop, 1991; Duval, 1999; Fennema & Tartre, 1985; Presmeg, 1986). Studies have linked spatial visualization ability, such as measured in mental rotation tasks, directly to mathematics self-efficacy (Pajares & Kranzler, 1995; Weckbacher & Okamoto, 2014), which in turn influences mathematics achievement (Casey, Nuttall, & Pezaris, 1997). With the important role that spatial visualization plays in learning mathematics, the recent identification of congenital aphantasia (Zeman, Dewar, & Della Sala, 2015), which is the lack of mental imagery ability, has raised new questions for mathematics education …

Discovering Driver Mutations In Biological Data, Yahya Bokhari

Theses and Dissertations

Background

Somatic mutations accumulate in human cells throughout life. Some may have no adverse consequences, but some of them may lead to cancer. A cancer genome is typically unstable, and thus more mutations can accumulate in the DNA of cancer cells. An ongoing problem is to figure out which mutations are drivers - play a role in oncogenesis, and which are passengers - do not play a role. One way of addressing this question is through inspection of somatic mutations in DNA of cancer samples from a cohort of patients and detection of patterns that differentiate driver from passenger mutations. …

Gas-Phase Studies Of Nucleophilic Substitution Reactions: Halogenating And Dehalogenating Aromatic Heterocycles, Leah L. Donham

Theses and Dissertations

Halogenated heterocycles are common in pharmaceutical and natural products and there is a need to develop a better understanding of processes used to synthesize them. Although the halogenation of simple aromatic molecules is well understood, the mechanisms behind the halogenation of aromatic heterocycles have been more problematic to elucidate because multiple pathways are possible. Recently, new, radical-based mechanisms have been proposed for heterocycle halogenation. In this study, we examine and test the viability of possible nucleophilic substitution, S_N2@X, mechanisms in the halogenation of anions derived from the deprotonation of aromatic heterocycles. All the experiments were done in a …

Kinetic Monte Carlo Simulation Of Binary Alloys, Timothy Craig Marshall

Theses and Dissertations

There are many tools to simulate physical phenomena. Generally, the simulation technique is defined by the size of the simulation area. Two well know techniques for simulating atom dynamics are kinetic Monte Carlo (kMC) and molecular dynamics (MD). In this work we simulate physical vapor deposition of binary metallic systems using the kMC technique. A sufficient quantity of atoms are deposited so that morphological features can be observed. Where kMC has fallen short we have used MD to supplement our results.

Toward Biologically-Inspired Self-Healing, Resilient Architectures For Digital Instrumentation And Control Systems And Embedded Devices, Shawkat Sabah Khairullah

Theses and Dissertations

Digital Instrumentation and Control (I&C) systems in safety-related applications of next generation industrial automation systems require high levels of resilience against different fault classes. One of the more essential concepts for achieving this goal is the notion of resilient and survivable digital I&C systems. In recent years, self-healing concepts based on biological physiology have received attention for the design of robust digital systems. However, many of these approaches have not been architected from the outset with safety in mind, nor have they been targeted for the automation community where a significant need exists. This dissertation presents a new self-healing digital …

Metalloglycomics: Investigating The Interactions Of Metal Complexes With Heparan Mimetics, Wyatt Johnson

Theses and Dissertations

Proteoglycans containing Heparan Sulfate (HS), a sulfated glycosaminoglycan (GAG), play a major role in the cell signaling process, interacting with many different proteins. HS is over expressed on the surface of many cancer cells. Enzymatic cleavage of HS-GAGs by heparanase causes release of angiogenic growth factors leading to tumor cell migration. Heparanase is also over-expressed in tumors with significant correlation between metastatic potential and heparanase activity. Proteoglycans and their associated enzymes are thus significant drug targets of high biological relevance.

A functional consequence of strong PPC-HS binding has been shown in proof-of-concept studies confirming inhibition of the model pentasaccharide, Fondaparinux, …

Opening The Gates To Ap Equity: A Case Study Of A Central Virginia High School’S Practices, Policies, And Characteristics Toward Proportional Black Student Representation In Advanced Placement Enrollment, Andrew R. Armstrong

Theses and Dissertations

Advanced Placement (AP) courses engage high school students with college curriculum taught by trained high school teachers, with an opportunity for students to earn college credit by passing the end-of-course AP exam. AP has evolved into an indicator of school quality, instructional rigor, and a consideration in the college admissions process. AP enrollment and exam performance outcomes for White students disproportionately surpass those for Black students. This study attempts to inform practice, policy, and programming toward more equitable enrollment outcomes for Black students through a single case study. The selected case school was the only high school among 38 in …

A Bibliometric Analysis Of The Proceedings Of The Association For Educational Communications And Technology (Aect) For The 1979-2009 Period, Vandy L. Pacetti-Donelson

Theses and Dissertations

Traditional journal analysis for the identification of disciplines is limited in developing areas of study due to the lack of journals specific to that area of study. Identifying knowledge domains worthy of study for the identification of developing disciplines has been difficult.

Conferences are at the forefront of building knowledge in scientific communities, particularly in technology related sectors, but less than 10% of conference proceedings are available in conventional knowledge databases. As a result, conference proceedings as a previously unconsidered knowledge domain, may provide the knowledge domain worthy of analysis to identify developmental and incremental change within developing areas of …

An Examination Of Teacher Perceptions Within Professional Learning Communities, Nicole Tiffany Reese

Theses and Dissertations

This applied dissertation was designed to determine the strength of the relationship between elementary teachers’ perceptions of the six school practices of the professional learning community (PLC) model and students’ science achievement and if differences exist among teachers at the target school district’s five elementary schools. The six practices of the PLC model are (a) shared and supportive leadership, (b) shared values and vision, (c) collective learning and application, (d) shared personal practice, (e) supportive conditions–relationships, and (f) supportive conditions–structures. The PLCs are presently defined as one of the most discussed school reforms within kindergarten to Grade 12. They assist …

John Frank Stevens: Panama Canal Mastermind And Pioneering Railroad Pathfinder, J. David Rogers, Lawrence M. Magura

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

John Frank Stevens began his civil engineering career as a rodman on a survey crew in Maine in 1872. He soon moved to Minneapolis, where he apprenticed himself, eventually becoming Assistant City Engineer. In 1876 he began working for railroads in the western United States. In 1882 Stevens began working for a contractor laying tracks for the Canadian Pacific Railroad in Saskatchewan. The next spring he became assistant engineer of location for the Canadian Pacific, completing the first transcontinental line linking Montreal with Vancouver in 1888. In 1889 James Jerome Hill retained Stevens as chief pathfinder for the new Great …

An Integrated Method For Forecasting Well Deliverability In Gas Condensate Reservoirs With Bottom Aquifer Drive, Abdulaziz Ellafi, Ralph E. Flori, Shari Dunn-Norman

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Gas condensate reservoirs constitute a significant portion of global hydrocarbon reserves. In these reservoirs, liquids develop in the pore space once bottomhole pressure falls below dew point. This results in the formation of a liquid bank near the wellbore region which decreases gas mobility, which then reduces gas inflow. In such complex reservoirs, it is important to correctly describe PVT impacts, adjustments to well test analysis and inflow performance, and then combine all effects in the reservoir analysis. The literature contains many references to individual adjustments of PVT analysis, well testing, or inflow performance for gas condensate reservoirs, but few …

Learning From Experience: An Automatic Ph Neutralization System Using Hybrid Fuzzy System And Neural Network, Ethar H.K. Alkamil, Seaar Al-Dabooni, Ahmed K. Abbas, Ralph Flori, Donald C. Wunsch

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

In oil and gas industry, the pH level is one of the most important indicators of mud contamination while drilling. Although the process has simple components, the pH neutralization process is complicated in the mud circulation system. This difficulty is due to the high nonlinearity of the process. In this paper, the fuzzy neural network (FNN) is integrated to the fuzzy logic controller (FLC) to create a system which identifies pH fluctuation into a drilling mud system, assesses and signals its severity. And then, it automatically actuates a chemical treating fluids valve (CTFV), such as Caustic Soda (CS), for neutralizing …