Digital Commons Network^™

Triatomines: Trypanosomatids, Bacteria, And Viruses Potential Vectors? [Review], Caroline Barreto Vieira, Yanna Reis Praça, Kaio Luís Da Silva Bentes, Paula Beatriz Santiago, Sofia Marcelino Martins Silva, Gabriel Dos Santos Silva, Flávia Nader Motta, Izabela Marques Dorado Bastos, Jaime Martins De Santana, Carla Nunes De Araújo

Harold W. Manter Laboratory of Parasitology: Library Materials

Triatominae bugs are the vectors of Chagas disease, a major concern to public health especially in Latin America, where vector-borne Chagas disease has undergone resurgence due mainly to diminished triatomine control in many endemic municipalities. Although the majority of Triatominae species occurs in the Americas, species belonging to the genus Linshcosteus occur in India, and species belonging to the Triatoma rubrofasciata complex have been also identified in Africa, the Middle East, South-East Asia, and in the Western Pacific. Not all of Triatominae species have been found to be infected with Trypanosoma cruzi, but the possibility of establishing vector transmission …

Museum Metabarcoding: A Novel Method Revealing Gut Helminth Communities Of Small Mammals Across Space And Time, Stephen E. Greiman, Joseph A. Cook, Vasyl V. Tkach, Eric P. Hoberg, Damian M. Menning, Andrew G. Hope, Sarah A. Sonsthagen, Sandra L. Talbot

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Natural history collections spanning multiple decades provide fundamental historical baselines to measure and understand changing biodiversity. New technologies such as next generation DNA sequencing have considerably increased the potential of museum specimens to address significant questions regarding the impact of environmental changes on host and parasite/pathogen dynamics. We developed a new technique to identify intestinal helminth parasites and applied it to shrews (Eulipotyphla: Soricidae) because they are ubiquitous, occupy diverse habitats, and host a diverse and abundant parasite fauna. Notably, we included museum specimens preserved in various ways to explore the efficacy of using metabarcoding analyses that may enable identification …

Predicting The Initial Spread Of Novel Asian Origin Influenza A Viruses In The Continental Usa By Wild Waterfowl, Alan. B. Franklin, Sarah N. Bevins, Jeremy W. Ellis, Ryan S. Miller, Susan A. Shriner, J. Jeffrey Root, Daniel P. Walsh, Thomas J. Deliberto

United States Department of Agriculture Wildlife Services: Staff Publications

Using data on waterfowl band recoveries, we identified spatially explicit hotspots of concentrated waterfowl movement to predict occurrence and spatial spread of a novel influenza A virus (clade 2.3.4.4) introduced from Asia by waterfowl from an initial outbreak in North America in November 2014. In response to the outbreak, the hotspots of waterfowl movement were used to help guide sampling for clade 2.3.4.4 viruses in waterfowl as an early warning for the US poultry industry during the outbreak. After surveillance sampling of waterfowl, we tested whether there was greater detection of clade 2.3.4.4 viruses inside hotspots. We found that hotspots …

Knowledge, Attitudes, And Practices Of Emergency Department Staff Towards Disaster And Emergency Preparedness At Tertiary Health Care Hospital In Central Saudi Arabia, Abdullah Nofal, Isamme Alfayyad, Anas Khan, Zohair Al Aseri, Amani Abu-Shaheen

Saudi Medical Journal

Objectives: To assess the knowledge, practices, and attitudes regarding disaster and emergency preparedness among Emergency Department (ED) staff. Methods: This cross-sectional study was conducted at Tertiary health care hospital in central Riyadh, Kingdom of Saudi Arabia. A self-administered survey was utilized to collect data from ED physicians and nurses. The questionnaire was divided into 5 sections viz; demographics, knowledge about disaster management and preparedness, attitudes about disaster planning, current role and practices, and familiarity towards emergency. Results: A 189 participants have completed the questionnaire. Two-third of the participants were below 30 years, and more than 85% were female. One hundred …

Human Immunodeficiency Virus Related Discrimination In General Dentistry, Ehab N. Alshouibi, Wafa S. Alalyani

Saudi Medical Journal

Objectives: To investigate HIV related discrimination among general dentists in Jeddah, Saudi Arabia; and to list factors affecting or causing healthcare providers to discriminate people living with HIV (PLWH). Methods: The current study takes place in Jeddah, western Saudi Arabia. The duration for accepting all responses was between March and November, 2017. In this cross-sectional study, we used a self-administered, structured questionnaire. The sample size was 430 general dentists practicing in Jeddah, Saudi Arabia. Descriptive statistics, mean, and standard deviation were calculated. Bivariate and multivariate analysis was carried out at p <0.05 level of significance. The Statistical Package for the Social Sciences (SPSS) version 22 (IBM Corp., Armonk, NY, USA) was used for data analysis. Results: In our study population, the total HIV related discrimination was 67.4%. Approximately 98.1% defer PLWH to the last appointment of the day, while 84.7% refer them to specialists. Furthermore,100% reported wearing double gloves, and 94.7% where wearing protective eye shields if they encounter HIV-patient in the clinic. Male participants were found to be 23% more likely to be discriminative compared to female participants, Moreover, participants who are confident to provide both surgical and non-surgical dental treatment for PLWH were found to be 52% less likely to be discriminative towards PLWH. Also, HIV discrimination is 33% higher in the private practice compared to the governmental practice. Conclusion: Human immunodeficiency virus related discrimination in the study population was affected by dentists’ gender, type of practice, and self-protective attitudes.

Mathematical Modeling Of Corona Virus In The United Arab Emirates, Alya Saif Ahmad Alshehhi

Theses

The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a viral in-fectious disease that can be transmitted to humans through interaction with infected ani-mals or humans. The Middle East respiratory syndrome (MERS) is still one of the main public health concerns in the Gulf region including United Arab Emirates. The fact that diseases have been imported into other parts of the world show the possibility of has a MERS pandemic. In this work, we are aiming to study a mathematical model of the MERS transmission among the UAE population and camels. The goal is to determine what are the paths of …

Vertical Transmission Of Naturally Occurring Bunyamwera And Insect-Specific Flavivirus Infections In Mosquitoes From Islands And Mainland Shores Of Lakes Victoria And Baringo In Kenya, Yvonne Ukamaka Ajamma, Thomas Ogao Onchuru, Daniel O. Ouso, David Omondi, Daniel K. Masiga, Jandouwe Villinger

All Peer-Reviewed Publications

Background: Many arboviruses transmitted by mosquitoes have been implicated as causative agents of both human and animal illnesses in East Africa. Although epidemics of arboviral emerging infectious diseases have risen in frequency in recent years, the extent to which mosquitoes maintain pathogens in circulation during inter-epidemic periods is still poorly understood. This study aimed to investigate whether arboviruses may be maintained by vertical transmission via immature life stages of different mosquito vector species. Methodology: We collected immature mosquitoes (egg, larva, pupa) on the shores and islands of Lake Baringo and Lake Victoria in western Kenya and reared them to adults. …

The Use Of Bacteriophages To Control Legionella Spp. In Environmental Water Samples, Naama Abdulla Ali Al-Kaabi

Theses

Legionnaires' disease is a potentially fatal form of pneumonia which can affect human, but principally affects those who are susceptible and predisposed to infection due to old age, illness, immunosuppressed and patients at risk. Legionnaires' disease is caused by Gram-negative rod bacteria called Legionella pneumophila. An estimation of 8,000 to 18,000 are actually confirmed cases of Legionnaires' disease per year in the USA. In the UAE, there has been an increase in the number of cases of Legionnaires’ disease which are associated with recent travel to Dubai. Incidents doubled between October 2016 and August 2017. Legionella pneumophila is found …

Comparison Of Bacterial And Viral Reduction Across Different Wastewater Treatment Processes, Aayushi R. Vagadia

USF Tampa Graduate Theses and Dissertations

Today billions of people live without access to basic sanitation facilities, and thousands die every week due to diseases caused by fecal contamination associated with improper sanitation. It has thus become crucial for decision makers to have access to relevant and sufficient data to implement appropriate solutions to these problems. The Global Water Pathogen Project http://www.waterpathogens.org/ is dedicated to providing an up-to-date source of data on pathogen reduction associated with different sanitation technologies that are important if the world is to achieve the Sustainable Development Goals (SDGs) related to health and sanitation provision. In this research, a subset of the …

Multistate Infestation With The Exotic Disease-Vector Tick Haemaphysalis Longicornis - United States, August 2017-September 2018, C. B. Beard, James Occi, Denise L. Bonilla, Andrea M. Egizi, Dina M. Fonseca, Gary P. Wormser, William Halperin

NYMC Faculty Publications

Haemaphysalis longicornis is a tick indigenous to eastern Asia and an important vector of human and animal disease agents, resulting in such outcomes as human hemorrhagic fever and reduction of production in dairy cattle by 25%. H. longicornis was discovered on a sheep in New Jersey in August 2017 (1). This was the first detection in the United States outside of quarantine. In the spring of 2018, the tick was again detected at the index site, and later, in other counties in New Jersey, in seven other states in the eastern United States, and in Arkansas. The hosts included six …

Home Return Following Invasive Mechanical Ventilation For The Oldest-Old Patients In Medical Intensive Care Units From Two Us Hospitals, Puthiery Va, Parth Rali, Harshitha Kota, Vivian Keenan, Sobia Mujtaba, Win Naing, Reka Salgunan, Irene Galperin, Oleg Epelbaum

NYMC Faculty Publications

Background: The aging of the US population has been associated with an increase in intensive care unit (ICU) utilization and correspondingly, invasive mechanical ventilation (IMV) among the oldest-old (age >/=80 years). While previous studies have examined ICU and IMV outcomes in the elderly, very few have focused on patient-centered outcomes, specifically home return, in the oldest-old. We investigated the rate of immediate home return following IMV in the medical ICU in previously home-dwelling oldest-old patients relative to that of a comparison group of 50-70-year olds. Methods: Data were extracted retrospectively from patient records at Elmhurst Hospital Center in Elmhurst, NY, …

Hand Hygiene Practices Among Health Care Workers In Rizgary Teaching Hospital, Peshtewan Dhaher Majeed, Salah Hasan Ali, Umeed Arshad Huwiezy

Polytechnic Journal

Health care associated infections are major causes of morbidity and mortality especially among the vulnerable groups and a majority of these infections are due to contamination of healthcare workers (HCWs) hands. Hand hygiene is a simple cost effective measure for preventing infections related to healthcare. Morbidity and mortality resulting from healthcare associated infections (HCAIs) can greatly be reduced by adherence to the recommended hand hygiene guidelines. Objectives: The objectives of this study were to determine the hand hygiene practices among healthcare workers (HCWs) in the Rizgary Teaching Hospital. Study design: A descriptive cross sectional study where HCWs were observed using …

Heat Shock Protein 40 And Immune Function In Altered Gravity, Amber M. Paul, Brooke D. Shepard, Sharmila Bhattacharya

Publications

In space, astronauts are more susceptible to pathogens, viral reactivation and immunosuppression, which poses limits to their health and the mission. Interestingly, during space flight, stress-inducible heat shock proteins (HSP) are robustly induced, and the overexpression of HSPs have been implicated in immune dysregulation, therefore HSPs may be critically involved in regulating immune homeostasis. HSP40/DNAJ1 plays a major role in proper protein translation and folding. Its loss of function has been implicated in susceptibility to microbial infection, while its overexpression has been implicated in autoimmunity, collectively suggesting its complicated, but necessary, role in maintaining immunological function. To determine the role …

Potential Role Of Csf Cytokine Profiles In Discriminating Infectious From Non-Infectious Cns Disorders., Danielle Fortuna, D. Craig Hooper, Amity L. Roberts, Larry A. Harshyne, Michelle Nagurney, Mark T. Curtis

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Current laboratory testing of cerebrospinal fluid (CSF) does not consistently discriminate between different central nervous system (CNS) disease states. Rapidly distinguishing CNS infections from other brain and spinal cord disorders that share a similar clinical presentation is critical. New approaches focusing on aspects of disease biology, such as immune response profiles that can have stimulus-specific attributes, may be helpful. We undertook this preliminary proof-of-concept study using multiplex ELISA to measure CSF cytokine levels in various CNS disorders (infections, autoimmune/demyelinating diseases, lymphomas, and gliomas) to determine the potential utility of cytokine patterns in differentiating CNS infections from other CNS diseases. Both …

Mitochondrial Replacement Therapy: How A Government For The People, Failed The People, Jeffery Mark Sauer

University of Miami Law Review

Despite having the potential to significantly reduce the passage of many lethal diseases and devastating birth defects, mitochondrial replacement therapy—a controversial medical procedure in which mitochondrial RNA from a healthy female replaces the mitochondrial RNA from the intended mother in vitro—will have no place in the United States anytime soon. Under the guise of purported safety concerns and ethical dilemmas, the Republican Congress used its “power of the purse” to halt any and all research furthering mitochondrial replacement therapy, notwithstanding the fact that many leaders in the medical community have advocated for further research. Several developed countries have already implemented …

U.N. Sovereign Immunity: Using The Haitian Experience To Transition From Absolute To Qualified Immunity, Brianna Sainte

University of Miami Law Review

The United Nations (“U.N.”) has been looked at globally and historically as an international organization that has given aid to millions of people in the hopes of promoting peace and reducing human rights violations. It is no surprise then that many countries have welcomed U.N. troops with open arms in the hopes of stabilizing communities. However, instead of receiving aid, imagine receiving a deadly disease. Imagine having the nearby river that has been your only source of water for drinking, laundry, and bathing for decades turned into a waste dump. It is from that river turned waste dump that you—and …

Kaposi’S Sarcoma-Associated Herpesvirus Seropositivity Is Associated With Type 2 Diabetes Mellitus: A Case–Control Study In Xinjiang, China, Meng Cui, Qiwen Fang, Jun Zheng, Zhanjun Shu, Yin Chen, Yage Fan, Juan Zhao, Charles Wood, Tiejun Zhang, Yan Zeng

Nebraska Center for Virology: Faculty Publications

Objective: To assess the potential relationship between Kaposi’s sarcoma-associated herpesvirus (KSHV) infection and type 2 diabetes mellitus (DM-2) in Xinjiang, China.

Methods: A case–control study of consecutively included DM-2 patients and normal controls was conducted among the Uygur and Han populations in Xinjiang Uygur Autonomous Region, China. Blood samples were collected and KSHV seroprevalence, antibody titers, and viral load were investigated. Logistic regression analysis and multiple linear regression analysis were applied to explore determinants of the main outcome measures.

Results: A total of 324 patients with DM-2 and 376 normal controls were included. The seroprevalence of KSHV was 49.1% (95% …

An Examination Of The Relationship Between Health Literacy And Dietary Practices Among College Students: A Test Of The Integrated Model Of Health Literacy, Alison B. Oberne

USF Tampa Graduate Theses and Dissertations

Overweight and obesity continue to plague Americans and contribute to decreased quantity and quality of life. Americans of all ages experience overweight and obesity; however, increasing rates occur during young adulthood. Young adults develop dietary practice behaviors that persist into adulthood and can contribute to weight-related chronic diseases. Approximately half of all young adults are enrolled in college, and, approximately 38% of college students are either overweight or obese.

Dietary practices are health behaviors that can either increase or decrease risk for overweight and obesity. Much research has explored predictors of dietary practices among college students; however, there is a …

Stress-Induced Heat Shock Protein 40 And Immune Function In Altered Gravity, Amber M. Paul, Brooke D. Shepard, Sharmila Bhattacharya

Publications

In space, astronauts are more susceptible to pathogens, viral reactivation and immunosuppression, which poses limits to their health and the mission. Interestingly, during space flight, stress-inducible heat shock proteins (HSP) are robustly induced, and the overexpression of HSPs have been implicated in immune dysregulation, therefore HSPs may be critically involved in regulating immune homeostasis. HSP40/DNAJ1 plays a major role in proper protein translation and folding. Its loss of function has been implicated in susceptibility to microbial infection, while its overexpression has been implicated in autoimmunity, collectively suggesting its complicated, but necessary, role in maintaining immunological function. To determine the role …

Hidden Cost Of Disease In A Free-Ranging Ungulate: Brucellosis Reduces Mid-Winter Pregnancy In Elk, Gavin C. Cotterill, Paul C. Cross, Arthur D. Middleton, Jared D. Rogerson, Brandon M. Scurlock, Johan T. Du Toit

Wildland Resources Faculty Publications

Demonstrating disease impacts on the vital rates of free‐ranging mammalian hosts typically requires intensive, long‐term study. Evidence for chronic pathogens affecting reproduction but not survival is rare, but has the potential for wide‐ranging effects. Accurately quantifying disease‐associated reductions in fecundity is important for advancing theory, generating accurate predictive models, and achieving effective management. We investigated the impacts of brucellosis (Brucella abortus) on elk (Cervus canadensis) productivity using serological data from over 6,000 captures since 1990 in the Greater Yellowstone Ecosystem, USA. Over 1,000 of these records included known age and pregnancy status. Using Bayesian multilevel models, …

Seasonal Dynamics Of Respiratory Tract Infections From Group A Streptococcus Beta Hemoliticus In The Region Of Gjakova, Kosovo, Arianeta Nura, Naser Ramadani, Etleva Hamzaraj

UBT International Conference

The aim of this study was to investigate the carrier rates of group A beta hemolytic Streptococcus (GAS) in upper respiratory tract during the various seasons of the year. We have performed a study in population of Gjakova region during the year 2017, were we have analysed 1590 cases. In the total cases that are studied from us, 84% has been negative in there culture and 16 % of this cases are resulted positive with presence of GAS. In our study the rate of isolation was 35 % in spring, 14 % in summer, 15 % in autumn and 36 …

Nursing Care In Children With Type 1 Diabetes Mellitus, Doruntina Ismaili, Fëllënza Spahiu, Lirije Beqiri, Afërdita Berisha

UBT International Conference

A life dependent from insulin certainly requires patience, support, care and a constant education from our side as professionals of medicine toward our patients who are affected by diabetes. The prevalence of this disease is increasing, whereas the incidence is approximately 4 cases per 100 000 inhabitants. Factors that affect this disease are many, ranging from the genetic basis to stress and trauma. The complications of this are inevitable that touch almost the whole system and bodies starting from the brain to the legs. Based on the research conducted the total number of children with type 1 diabetes mellitus in …

Volume 56, Number 11: October 24, 2018, University Of North Dakota

University Letter Archive

No abstract provided.

The Lumberjack, October 24, 2018

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

Vaccine Myths: Setting The Record Straight, Julie A. Boom, Rachel M. Cunningham, Lindy U. Mcgee

Journal of Family Strengths

Despite their standing as one of the most remarkable public health achievements, vaccines have been surrounded by dangerous myths since the development of the smallpox vaccine in the 18th century. In recent decades, with the publication of a fraudulent article linking vaccines to autism, the involvement of celebrities in the debate, and the rise of the internet and social media as sources for information for patients, these myths have become more widespread. This paper reviews four common vaccine myths: vaccines cause autism, vaccines are not safe, too many vaccines are given too soon, and the influenza vaccine is not necessary. …

Human Trafficking: It’S Not Just A Crime, Frances H. Recknor, Makini Chisolm-Straker

Journal of Family Strengths

Human trafficking, although commonly conceived of as a crime, is also a matter for the fields of health and public health. Trafficked individuals suffering physical, sexual, and/or psychological abuse can experience acute and chronic health sequelae, bringing them to the attention of health and/or mental health professionals. Communicable infections affect many trafficked individuals and can be transmitted to those not trafficked. The factors that contribute to people being trafficked, like poverty, educational disparities, and systematic oppression based upon identities, are multifaceted and interlinked with other trauma experiences. Incorporation of public health principles into anti-trafficking efforts facilitates a comprehensive and holistic …

Pharmacists’ Knowledge Of Social Determinants Of Health In Post-Graduate Pharmacy Residency Programs, Rachel N. Chandra

Master of Public Health Program Student Publications

Background: Clinical pharmacists and their training programs can play a key role in helping to address social determinants of health (SDoH) by transforming healthcare beyond the traditional clinical approaches. Pharmacists’ knowledge of SDoH in post-graduate residency programs are key skills necessary for creating an impact in healthcare outcomes.

Purpose: The purpose of this project was to assess U.S. Department of Veterans Affairs (VA) post-graduate residency program directors’ and residents’ knowledge about SDoH. Methods: An IRB exempt questionnaire was created via Survey Monkey (™) and administered to postgraduate pharmacy residents (N = 618) and residency program directors (RPDs) (N = 235) …

Kawasaki Disease: Two Case Reports From The Aga Khan Hospital, Dar Es Salaam-Tanzania, Mariam Noorani, Nuruddin Lakhani

Paediatrics and Child Health, East Africa

Background: Kawasaki disease is a common childhood vasculitis which may result in cardiovascular morbidity if not adequately treated. Its epidemiology in the African region is not well described. Its features may mimic other childhood infections and hemoglobinopathies and it is rarely diagnosed in the East African region. These are the first reports of this disease from Tanzania. Case presentation We present two cases of complete Kawasaki disease seen over a 2 year period and diagnosed as per the criteria defined by the American Heart Association. One child was and infant and the other a 3 year old. Both of them …

Kawasaki Disease: Two Case Reports From The Aga Khan Hospital, Dar Es Salaam-Tanzania, Mariam Noorani, Nuruddin Lakhani

Faculty of Health Sciences, East Africa

Background

Kawasaki disease is a common childhood vasculitis which may result in cardiovascular morbidity if not adequately treated. Its epidemiology in the African region is not well described. Its features may mimic other childhood infections and hemoglobinopathies and it is rarely diagnosed in the East African region. These are the first reports of this disease from Tanzania. Case presentation We present two cases of complete Kawasaki disease seen over a 2 year period and diagnosed as per the criteria defined by the American Heart Association. One child was and infant and the other a 3 year old. Both of them …

How The Human Immune System Reacts To Stress Such As Drowning, Luke O'Neill Ph.D., Frs

International Journal of Aquatic Research and Education

No abstract provided.