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Hexapod Herald - Vol. 30, No. 1, February 2018

Hexapod Herald and Other Entomology Department Newsletters

Contents: Welcome - Congratulations - Faculty News - Gamma Sigma Delta Awards - Publications - Blast from the Past - Baxendale Retirement Reception

Can They Do That? : The Limits Of Governmental Power Over Medical Treatment, Paul Mclaughlin

Law Library Faculty Scholarship

Recommended citation: Paul Jerome McLaughlin Jr. (2017) Can They Do That?: The Limits of Governmental Power over Medical Treatment, Journal of Legal Medicine, 37:3-4, 371-388, DOI: 10.1080/01947648.2017.1385039

Occupational Health And Safety Screening For Animal Handlers

Environmental Health & Safety Policies

UHSP is committed to providing a safe working environment for all personnel, including individuals who have contact with animals in research. University of Health Sciences and Pharmacy in St. Louis (UHSP) maintains an occupational health program for employees coming into contact with animals intended for use in research that includes education, use of appropriate personal protective equipment and screening for risk and additional precautions or restrictions on animal use by an employee.

Biom 402.01: Medical Bacteriology And Mycology, Michael F. Minnick

University of Montana Course Syllabi

No abstract provided.

Agrochemicals Increase Risk Of Human Schistosomiasis By Supporting Higher Densities Of Intermediate Hosts, Neal T. Halstead, Christopher M. Hoover, Arathi Arakala, David J. Civitello, Guilio A. De Leo, Manoj Gambhir, Steve A. Johnson, Nicolas Jouanard, Kristin A. Loerns, Karena Nguyen, Jason R. Rohr

Integrative Biology Faculty and Staff Publications

Schistosomiasis is a snail-borne parasitic disease that ranks among the most important water-based diseases of humans in developing countries. Increased prevalence and spread of human schistosomiasis to non-endemic areas has been consistently linked with water resource management related to agricultural expansion. However, the role of agrochemical pollution in human schistosome transmission remains unexplored, despite strong evidence of agrochemicals increasing snail-borne diseases of wildlife and a projected 2- to 5-fold increase in global agrochemical use by 2050. Using a field mesocosm experiment, we show that environmentally relevant concentrations of fertilizer, a herbicide, and an insecticide, individually and as mixtures, increase densities …

Cutr Connections [February 2018], Cutr

CUTR Newsletters

No abstract provided.

Recently Integrated Alu Insertions In The Squirrel Monkey (Saimiri) Lineage And Application For Population Analyses, Mark Batzer, Jasmine N. Baker, Jerilyn A. Walker, Michael W. Denham, Charles D. Loupe

Faculty Publications

Background: The evolution of Alu elements has been ongoing in primate lineages and Alu insertion polymorphisms are widely used in phylogenetic and population genetics studies. Alu subfamilies in the squirrel monkey (Saimiri), a New World Monkey (NWM), were recently reported. Squirrel monkeys are commonly used in biomedical research and often require species identification. The purpose of this study was two-fold: 1) Perform locus-specific PCR analyses on recently integrated Alu insertions in Saimiri to determine their amplification dynamics, and 2) Identify a subset of Alu insertion polymorphisms with species informative allele frequency distributions between the Saimiri sciureus and Saimiri boliviensis groups. …

Use Of 'Eradication' In Hiv Cure-Related Research: A Public Health Debate, Karine Dubé, Stuart Luter, Breanne Lesnar, Luke Newton, Jerome T. Galea, Brandon Brown, Sarah Gianella

Social Work Faculty Publications

Background: The landscape of Human Immunodeficiency Virus (HIV) research has changed drastically over the past three decades. With the remarkable success of antiretroviral treatment (ART) in decreasing AIDS-related mortality, some researchers have shifted their HIV research focus from treatment to cure research. The HIV cure research community often uses the term eradication to describe the science, and talks about eradicating the virus from the body. In public discourse, the term eradication could be conflated with disease eradication at the population level. In this paper, we call for a reframing of HIV cure research as control, as it is a …

Improving Pneumococcal Vaccine Uptake In Veterans With Chronic Lymphocytic Leukemia Through A Virtual Clinic, Brigid M. Wilson, L. Arfons, Federico Perez, Robin L.P. Jump

Faculty Scholarship

Through a “virtual clinic,” we used the electronic medical record to identify and intervene upon patients with chronic lymphocytic leukemia (CLL) who were not current for pneumococcal vaccines. Within 180 days, 100/160 patients (62%) received the recommended pneumococcal vaccine. A virtual clinic may improve vaccination rates among high-risk patient populations.

Latent ;Toxoplasma Gondii; Infection Moderates The Association Between The C677t Mthfr Polymorphism And Cognitive Function In U.S. Adults, Andrew Nathan Berrett

Theses and Dissertations

Sufficient blood concentrations of folate and the products from its metabolism arenecessary for several cellular functions. The C677T MTHFR polymorphism, present in over halfof the U.S. population, reduces the efficiency of folate metabolism and has been linked to theonset of multiple psychiatric disorders and cognitive decline. The intracellular parasiteToxoplasma gondii can infect the human brain and is associated with increased prevalence ofpsychiatric disorders and cognitive decline. In vitro studies have found that Toxoplasma gondiimay salvage unmetabolized folate from host cells. Since the C677T MTHFR polymorphism andinfection by Toxoplasma gondii both affect folate metabolism or availability, I used data fromthe third …

Biographical Feature: Richard B. (Tom) Thomson, Jr., Ph.D., D(Abmm), F(Aam), Erik Munson

Clinical Lab Sciences Faculty Research and Publications

No abstract provided.

Lactate And Immunosuppression In Sepsis, Benjamin Nolt, Fei Tu, Xiaohui Wang, Tuanzhu Ha, Randi Winter, David L. Williams, Chuanfu Li

ETSU Faculty Works

Serum lactate levels are traditionally interpreted as a marker of tissue hypoxia and often used clinically as an indicator of severity and outcome of sepsis/septic shock. Interestingly, recent studies involving the effects of tumor-derived lactate suggest that lactate itself may have an immunosuppressive effect in its local environment. This finding adds to the recent advances in immunometabolism that shed light on the importance of metabolism and metabolic intermediates in the regulation of innate immune and inflammatory responses in sepsis. In this article, we summarize recent studies, showing that the activation of immune cells requires aerobic glycolytic metabolism and that lactate …

Realizing Restorative Justice: Legal Rules And Standards For School Discipline Reform, Lydia Nussbaum

UC Law Journal

No abstract provided.

The Scholarly Publishing Scene-Getting Attention, Myer Kutz

Against the Grain

No abstract provided.

And They Were There-Reports Of Meetings, Ramue K. Kubilius, Sever Bordeianu

Against the Grain

No abstract provided.

Latent Toxoplasma Gondii Infection Moderates The Association Between The C677t Mthfr Polymorphism And Cognitive Function In U.S. Adults, Andrew Nathan Berrett

Theses and Dissertations

Sufficient blood concentrations of folate and the products from its metabolism are necessary for several cellular functions. The C677T MTHFR polymorphism, present in over half of the U.S. population, reduces the efficiency of folate metabolism and has been linked to the onset of multiple psychiatric disorders and cognitive decline. The intracellular parasite Toxoplasma gondii can infect the human brain and is associated with increased prevalence of psychiatric disorders and cognitive decline. In vitro studies have found that Toxoplasma gondii may salvage unmetabolized folate from host cells. Since the C677T MTHFR polymorphism and infection by Toxoplasma gondii both affect folate metabolism …

The Cowl - V.82 - N.15 - Feb 1, 2018

The Cowl

The Cowl - student newspaper of Providence College. Volume 82, Number 15 - February 1, 2018. 24 pages.

Cholera And Climate Change: Pursuing Public Health Adaptation Strategies In The Face Of Scientific Debate, Robin Kundis Craig

Utah Law Faculty Scholarship

Climate change will affect the prevalence, distribution, and lethality of many diseases, from mosquito-borne diseases like malaria and dengue fever to directly infectious diseases like influenza to water-borne diseases like cholera and cryptosporidia. This Article focuses on one of the current scientific debates surrounding cholera and the implications of that debate for public health-related climate change adaptation strategies.

Since the 1970s, Rita Colwell and her co-researchers have been arguing a local reservoir hypothesis for cholera, emphasizing that river, estuarine, and coastal waters often contain more dormant forms of cholera attached to copepods, a form of zooplankton. Under this hypothesis, climatically …

Molecular Characterization Of Hard Tick Haemaphysalis Longicornis From China By Sequences Of The Internal Transcribed Spacers Of Ribosomal Dna, Zhong-Bo Li, Guo-Hua Liu, Tian-Yin Cheng

Harold W. Manter Laboratory of Parasitology: Library Materials

In the present study, the entire first and second internal transcribed spacer (ITS-1 and ITS-2) regions of nuclear ribosomal DNA (rDNA) of Haemaphysalis longicornis from China were amplified by polymerase chain reaction. The 45 representative amplicons were sequenced, and sequence variation in the ITS was examined. The ITS sequences of H. longicornis were 3644 bp in size, including the part of 18S rDNA, 28S rDNA sequences and the complete ITS-1, 5.8S rDNA and ITS-2 sequences. Sequence analysis revealed that the ITS-1, 5.8S rDNA and ITS-2 of this hard tick were 1582, 152, and 1610 bp in size, respectively. The intra-specific …

Human Factors And Simulation In Emergency Medicine, Emily M. Hayden, Ambrose H. Wong, Jeremy Ackerman, Margaret K. Sande, Charles Lei, Leo Kobayashi, Michael Cassara, Dylan D. Cooper, Kimberly Perry, William E. Lewandowski, Mark W. Scerbo

Psychology Faculty Publications

This consensus group from the 2017 Academic Emergency Medicine Consensus Conference "Catalyzing System Change through Health Care Simulation: Systems, Competency, and Outcomes" held in Orlando, Florida, on May 16, 2017, focused on the use of human factors (HF) and simulation in the field of emergency medicine (EM). The HF discipline is often underutilized within EM but has significant potential in improving the interface between technologies and individuals in the field. The discussion explored the domain of HF, its benefits in medicine, how simulation can be a catalyst for HF work in EM, and how EM can collaborate with HF professionals …

Categorizing Security For Security Management And Information Resource Management, Yejun Wu, Fansong Meng

Journal of Strategic Security

There are various definitions and dimensions of security, and there is no comprehensive taxonomy of security. The existing classifications of security are fragmented, scattered, and divergent, binging challenges in the management of security and the management of information resources about security. This research aims to study the problems of security categorization in existing knowledge organization systems, and to develop a comprehensive taxonomy of security. Through thematic analysis of the literature about security, we found that, despite the various definitions and dimensions of security, there is a common feature of security. That is, security is expressed in this pattern: subject wants …

High Smad7 And P-Smad2,3 Expression Is Associated With Environmental Enteropathy In Children, Sana Syed, Vincenzo Dinallo, Najeeha Talat Iqbal, Laura Di Iorio, Davide Di Fusco, Shan Guleria, Beatrice C. Amadi, Kamran Sadiq, Christopher Moskaluk, Syed Asad Ali

Department of Paediatrics and Child Health

Enteropathies such as Crohn's disease are associated with enteric inflammation characterized by impaired TGF-β signaling, decreased expression of phosphorylated (p)-SMAD2,3 and increased expression of SMAD7 (an inhibitor of SMAD3 phosphorylation). Environmental enteropathy (EE) is an acquired inflammatory disease of the small intestine (SI), which is associated with linear growth disruption, cognitive deficits, and reduced oral vaccine responsiveness in childrenp-SMAD2,3 levels (using Western blotting) in EE duodenal biopsies (N = 19 children, 7 from Pakistan, 12 from Zambia) and comparing these with healthy controls (Ctl) and celiac disease (CD) patients from Italy. Densitometric analysis of immunoblots showed that EE SI biopsies …

Lipid Nanocapsules For Brain Targeting Of Nimodipine, Karim Mohsen

Theses and Dissertations

Subarachnoid hemorrhage (SAH) is the leading cause of death in stroke patients who suffer from vasospasms with incidence of 70%. SAH prevents sufficient oxygen supply to the brain causing ischemia and death. FDA approved only nimodipine (NM) for treatment of vasospasm associated with SAH. Nevertheless, NM has poor pharmacokinetic properties, which limit its clinical efficacy. NM is susceptible to first-pass metabolism and has low solubility and thereby poor bioavailability. The objective of this study is to assess the nose-brain pathway in brain targeting of NM-loaded lipid nanocapsules (LNCs) after intranasal administration. Solvent-free phase inversion temperature technique was used to prepare …

The George-Anne, Georgia Southern University

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Multimorbidity In South Asian Adults: Prevalence, Risk Factors And Mortality., Kalpana Singh, Shivani A. Patel, Suddhendu Biswas, Roopa Shivashankar, Dimple Kondal, Vamadevan Ajay, Ranjit Mohan Anjana, Zafar Fatmi, Mohammed K. Ali, Muhammad Masood Kadir

Community Health Sciences

Background:

We report the prevalence, risk factors and mortality associated with multimorbidity in urban South Asian adults.

Methods:

Hypertension, diabetes, heart disease, stroke and chronic kidney disease were measured at baseline in a sample of 16 287 adults ages ≥20 years in Delhi, Chennai and Karachi in 2010-11 followed for an average of 38 months. Multimorbidity was defined as having ≥2 chronic conditions at baseline. We identified correlates of multimorbidity at baseline using multinomial logistic models, and we assessed the prospective association between multimorbidity and mortality using Cox proportional hazards models.

Results:

The adjusted prevalence of multimorbidity was 9.4%; multimorbidity …

Volume 55, Number 24: January 31, 2018, University Of North Dakota

University Letter Archive

No abstract provided.

V-Atpase Roles In Prostate Cancer, Yamhilette Licon Munoz

Biomedical Sciences ETDs

Vacuolar ATPase (V-ATPase) is responsible for maintaining the acidic pH of the endomembrane system in eukaryotic cells. V-ATPase active transport of protons generates the differential luminal pH in lysosomes, endosomes, and the Golgi. In addition to intracellular V-ATPase, cancer cells have V-ATPase at the plasma membrane. Plasmalemmal V-ATPase acidifies the extracellular milieu and enhances cell motility and invasion, evidence that V-ATPase contributes to tumorigenic phenotypes. We studied V-ATPase cellular functions in prostate cancer (PCa), the most commonly diagnosed cancer for men in the United States. V-ATPase inhibitors decreased invasion and migration of PCa cells. In aggressive PCa cell lines, C4-2B …

Low Perceived Control Over Health Is Associated With Lower Treatment Uptake In A High Mortality Population Of Bolivian Forager-Farmers, Sarah Alami, Jonathan Stieglitz, Hillard Kaplan, Michael Gurven

ESI Publications

Indigenous people worldwide suffer from higher rates of morbidity and mortality than neighboring populations. In addition to having limited access to public health infrastructure, indigenous people may also have priorities and health perceptions that deter them from seeking adequate modern healthcare. Here we propose that living in a harsh and unpredictable environment reduces motivation to pursue deliberate, costly action to improve health outcomes. We assess whether variation in Health Locus of Control (HLC), a psychological construct designed to capture self-efficacy with respect to health, explains variation in treatment uptake behavior among Tsimane Amerindians (N=690; age range: 40–89 years; 55.8% female; …

Mathematical Modeling In Law And Political Science: Learning From Public Health, William Butler

The Pegasus Review: UCF Undergraduate Research Journal

This paper provides an overview of mathematical modeling in public health policy and recommends the teaching of mathematical models in other fields, like law and undergraduate political science studies. First, I describe various facets of public health in terms of their scope and goals. The complex nature of public health lends way to a description of mathematical modeling and the role it can serve. Various mathematical solution concepts are also provided, including the SIR model, reproductive number, and game theory. Finally, I explain why knowledge of simple models is beneficial for students in pre-professional programs in law and political science. …

A Review Of Combination Antimicrobial Therapy For Enterococcus Faecalis Bloodstream Infections And Infective Endocarditis, Maya Beganovic, K. Luther, Louis B. Rice, Cesar A. Arias, Michael J. Rybak, Kerry L. Laplante

Pharmacy Practice and Clinical Research Faculty Publications

Enterococci, one of the most common causes of hospital-associated infections, are responsible for substantial morbidity and mortality. Enterococcus faecalis, the more common and virulent species, cause serious high-inoculum infections, namely infective endocarditis, that are associated with cardiac surgery and mortality rates that remained unchanged for the last 30 years. The best cure for these infections are observed with combination antibiotic therapy; however, optimal treatment has not been fully elucidated. It is the purpose of this review to highlight treatment options, their limitations, and provide direction for future investigative efforts to aid in the treatment of these severe infections. While ampicillin …