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Animal Science E-Newsletter, November 2018, University Of Arkansas, Fayetteville. Department Of Animal Sciences

Animal Science e-Newsletter

No abstract provided.

Trex1 Is Expressed By Microglia In Normal Human Brain And Increases In Regions Affected By Ischemia, Parul H. Kothari, Grant R. Kolar, Joanna C. Jen, Rula Hajj-Ali, Paula Bertram, Robert E. Schmidt, John P. Atkinson

Biological Sciences Faculty Research & Creative Works

Background: Mutations in the three-prime repair exonuclease 1 (TREX1) gene have been associated with neurological diseases, including Retinal Vasculopathy with Cerebral Leukoencephalopathy (RVCL). However, the endogenous expression of TREX1 in human brain has not been studied. Methods: We produced a rabbit polyclonal antibody (pAb) to TREX1 to characterize TREX1 by Western blotting (WB) of cell lysates from normal controls and subjects carrying an RVCL frame-shift mutation. Dual staining was performed to determine cell types expressing TREX1 in human brain tissue. TREX1 distribution in human brain was further evaluated by immunohistochemical analyses of formalin-fixed, paraffin-embedded samples from normal controls and patients …

Poll Pirate, Ron Singer

Word Ways

A humorous essay on Parrots and parrot speech.

Criticise A Name (Otherwise: Transposing American Cities), Darryl Francis

Word Ways

A large listing of transposals for the names of all US cities with populations over 100.000.

Word Ways V.51 No.4 Complete Issue

Word Ways

All of the articles in this issue in one complete document.

Connections 11/2018, College Of Health And Human Services

College of Health and Human Services Newsletter

• College all-hands meeting raises money for United Way
• Faculty receive inaugural award for study abroad curriculum
• CHHS offers Bronco Brain Break before finals: December 5
• Faculty elected vice chair of state committee
• Disrupting Disparities: continuum of care in Michigan
• AHEC fall 2018 newsletter
• HHS on Social Media
• In other news

November 2018 Cehd Newsletter, College Of Education And Human Development

College of Education and Human Development News

• CEHD Opens New Student Success Center
• "Keep Smiling!" Apparel
• Two Faculty Receive Awards
• CEHD Professor Emeritus Passes
• Student Services Suite Named
• Upcoming Events

November And December 2018 News Items, Office Of Vice President For Research

Research and Discovery News

• 'Writing Winning Grant Proposals' Grant Writing Workshop
• NSF Major Research Instrumentation Grant
• NSF CAREER Workshop
• Workshop for Faculty Research and Creative Activities Award Available

No. 16: Cheap Industrial Food And The Urban Margins, Tony Weis, Marylynn Steckley, Bruce Frayne

Hungry Cities Partnership

From the middle of the 20th century onwards, the productivity gains associated with high-input, high-yield monocultures and livestock operations have become increasingly central to global food security and to dynamics of urbanization across the global south. On one hand, competition has deflated prices and helped undermine the viability of small farm livelihoods in many places. On the other hand, rising flows of cheap food have effectively subsidized urban migration in impoverished urban and peri-urban settings. But this cheapness is highly deceptive, as it hinges on the failure to account for an array of biological and physical costs – which can …

Tumor Infiltrating Lymphocyte Recruitment After Peri-Lymphatic Irx-2 Cytokine Immunotherapy In Resectable Breast Cancer And Head And Neck Carcinoma, Joanna Pucilowska, Venkatesh Rajamanickam, Nikki Moxon, Monil Shah, Maritza Martel, Alison Conlin, James E. Egan, David B. Page

Society for Immunotherapy of Cancer 2018 Annual Meeting Posters

Background: The IRX-2 biologic is a subcutaneous injectable immunotherapy composed of IL-2 and other cytokines derived from stimulated lymphocytes. Preclinically, IRX-2 activates T cells, natural killer cells, macrophages, and dendritic cells, and facilitates maturation of antigen-presenting cells.Tumor-infiltrating lymphocytes (TILs) are associated with improved outcomes in many cancers including early stage breast cancer (ESBC) and head and neck squamous cell carcinoma (HNSCC). We report data on TIL recruitment associated with pre-operative IRX-2 in a phase Ib ESBC trial, as well as phase Ib and IIa HNSCC trials.

Methods: The pre-operative IRX-2 regimen was evaluated in both ESBC and HNSCC trials for …

Single Cell Sequencing To Identify Tcrs That Recognize Autologous Tumor Cells After Vaccination With Allogeinic Dribble Vaccine, Hong-Ming Hu, Christopher C. Paustian, Zhifa Wen, Tarsem L. Moudgil, Traci L. Hilton, Sam Bookhardt, Guangjie Yu, Eric Tran, Venkatesh Rajamanickam, Walter Urba, Rachel E. Sanborn, Bernard A. Fox

Society for Immunotherapy of Cancer 2018 Annual Meeting Posters

Background: Adoptive immunotherapy with tumor-specific TCR gene-modified T cells has the potential to eradicate bulky disease. Traditional methods of TCR identification require lengthy in vitro culture to generate clonal T-cell populations, which adds time and complexity to this promising therapy. Here we described a simplified and reliable method to identify TCRs by single cell TCR sequencing of cells sorted with antibodies against T-cell surface markers that are up-regulated only when they are stimulated with specific tumor cell antigens.

Methods: A tumor-infiltrating lymphocyte (TIL) culture with T cells reactive against autologous tumor was generated from a brain metastasis of a patients …

Delayed Immune-Related Events After Discontinuation Of Immunotherapy – Dire Syndrome?, Marcus Couey, R. Bryan Bell, Ashish Patel, Marka R Crittenden, Brendan Curti, Rom Leidner

Society for Immunotherapy of Cancer 2018 Annual Meeting Posters

Background: Although the temporality of immune-related adverse events (irAE) is well-recognized during immunotherapy to be highly variable and often delayed,[1] post-immunotherapy irAE are rarely described and potentially under-recognized. In 2013, two cases were reported in abstract form in Deutschen Dermatologischen Gesellschaft.[2] In July 2018 a case of autoimmune hepatitis eight months post-immunotherapy was reported in The Oncologist[3] and a dermatologic series appeared online in JAMA Dermatology.[4] With expanding indications for IO and an increasing number of clinical trials in the curative-neoadjuvant setting, larger numbers of patients are being treated in earlier stages of disease and often for short courses. Given …

Prep And Condom Use: A Tale Of Unintended Consequences?, Lauren Maziarz

Public and Allied Health Faculty Publications

No abstract provided.

Ceteal News, November/December 2018, Ceteal, Coastal Carolina University

CeTEAL Newsletter

• Critical Thinking Elements Map to Final Disciplinary Projects
• Professional Development Opportunities
• Source Evaluation Through Lateral Reading
• Implementing Critical Thinking in Your Classes
• Contingency Instruction: Critical Thinking Module

Reactive Ion Plasma Modification Of Poly(Vinyl‐Alcohol) Increases Primary Endothelial Cell Affinity And Reduces Thrombogenicity, Patrick Jurney, Deirdre Anderson, Grace Pohan, Evelyn Yim, Monica Hinds

Faculty Publications

Bulk material properties and luminal surface interaction with blood determine the clinical viability of vascular grafts, and reducing intimal hyperplasia is necessary to improve their long‐term patency. Here, the authors report that the surface of a biocompatible hydrogel material, poly(vinyl alcohol) (PVA) can be altered by exposing it to reactive ion plasma (RIP) in order to increase primary endothelial cell attachment. The power and the carrier gas of the RIP treatment are varied and the resultant surface nitrogen, water contact angle, as well as the ability of the RIP‐treated surfaces to support primary endothelial colony forming cells is characterized. Additionally, …

Virtual Interaction And Adolescent Cognitive Development, Suresh Joshi

Teacher India

How does the use of technology impact learning and teaching in adolescents? What are the benefits and concerns?

Arab American College Students: What Predicts Their Engagement With The Israeli/Palestinian Conflict?, Manal Yazbak Abu Ahmad, Adrienne B. Dessel, Noor Ali

Peace and Conflict Studies

Arab and Jewish U.S. college students are impacted by the Israeli/Palestinian (I/P) conflict and heated interactions among students have erupted across campuses. There is a dearth of research on Arab American student perspectives on this conflict and on their interactions with Jewish students in higher education settings. This study seeks to further our understanding of these topics by reporting on a quantitative survey of Arab American college students (n=66). We examined dependent variables of Arab students seeking education on the I/P conflict, and interest in collaborating with Jewish students for peace. Independent variables were gender, religion, having Jewish friends, learning …

An Alternative To Violence In Education, Michelle Savard

Peace and Conflict Studies

It is imperative that transformative educators understand how education can be manipulated to serve political and authoritarian agendas and to recognize its subtle manifestations in order to reshape education for the purposes of fostering peace, cooperation and acceptance. Bush and Saltarelli (2000) assert that in its extremes, education can have “two faces”. It can be used as a tool to stimulate political unrest, foster hatred, justify violence and promote inequities; or in the case of peace education, facilitate the reconstruction of fragile states. Yet peace education programs continue to be criticized for their lack of rigorous evaluations largely by those …

Odontogenic Abscesses In Rhesus Macaques (Macaca Mulatta) Of Cayo Santiago, Hong Li, Wenjing Luo, Anna Feng, Michelle L. Tang, Terry B. Kensler, Elizabeth Maldonado, Octavio A. Gonzalez, Matthew J. Kessler, Paul C. Dechow, Jeffrey L. Ebersole, Qian Wang

Center for Oral Health Research Faculty Publications

Objectives
Odontogenic abscesses are one of the most common dental diseases causing maxillofacial skeletal lesions. They affect the individual's ability to maintain the dental structures necessary to obtain adequate nutrition for survival and reproduction. In this study, the prevalence and pattern of odontogenic abscesses in relation to age, sex, matriline, and living periods were investigated in adult rhesus macaque skeletons of the free-ranging colony on Cayo Santiago, Puerto Rico.

Materials and Methods
The skulls used for this study were from the skeletons of 752 adult rhesus macaques, aged 8–31 years, and born between 1951 and 2000. They came from 66 …

Anti-Apoptotic Effects Of Human Placental Hydrolysate Against Hepatocyte Toxicity In Vivo And In Vitro, Dong Ho Bak, Jungtae Na, Mi Ji Choi, Byung Chul Lee, Chang Taek Oh, Jeom Yong Kim, Hae Jung Han, Moo Joong Kim, Tae Ho Kim, Beom Joon Kim

Biological Sciences Faculty Publications

Apoptosis and oxidative stress are essential for the pathogenesis of acute liver failure and fulminant hepatic failure. Human placental hydrolysate (hPH) has been reported to possess antioxidant and anti-inflammatory properties. In the present study, the protective effects of hPH against D-galactosamine (D-GalN)- and lipopolysaccharide (LPS)-induced hepatocyte apoptosis were investigated in vivo. In addition, the molecular mechanisms underlying the anti-apoptotic activities of hPH against D-GalN-induced cell death in vitro were examined. Male Sprague-D awley rats were injected with D-GaIN/LPS with or without the administration of hPH. Rats were sacrificed 24 h after D-GaIN/LPS intraperitoneal injection, and the blood and liver samples …

College Of Health Sciences E-Newsletter, November 2018, Irvin B. Harrell (Editor)

Ellmer College of Health Sciences Newsletters

November 2018 issue of Old Dominion University's College of Health Sciences Newsletter.

The Impact Of A Poverty Simulation On Baccalaureate Nursing Students’ Attitudes, Kristen Smith

Doctor of Nursing Practice Scholarly Projects

Poverty is an ongoing issue in the United States, with major implications for the health of U.S. citizens. In order to provide compassionate care, nurses must understand their own attitudes towards those living in poverty. The purpose of this study was to evaluate for possible changes in attitudes towards poverty in junior level BSN students after a poverty simulation intervention. Participants were surveyed using the Yun and Weaver’s Short Form Attitudes towards Poverty (SFATP) tool, which looks three factors of poverty attitudes: personal deficiency, stigma, and structural perspective.

The Adult Learning Theory provided the theoretical framework for the study. This …

Evaluation Of Three Forest-Based Bioenergy Development Strategies In The Inland Northwest, United States, Jill Moroney

Human-Environment Systems Research Center Faculty Publications and Presentations

In this article, we compare three bioenergy scenarios that use woody biomass from US Inland Northwest forests. The scenarios are based on current bioenergy research, development efforts, and stakeholder input. They include a small-scale system that produces drop-in transportation biofuel and biochar, a large, regional system that produces bio-aviation fuel, and a midsized pellet production system. We modeled woody biomass harvest, processing, and transportation, and then evaluated profitability and potential socioeconomic impacts to determine the overall viability of each strategy. Through interviews, we found widespread stakeholder support for all three scenarios. Wood-pellet production was profitable and feasible with current prices …

Nebline, November/December 2018

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

Feature: Youth Voice benefits youth, communities

Food & Health

Farm & Acreage

Pests & Wildlife

Horticulture

Early Childhood

4-H & Youth

and other extension news and events

Prevailing Clusters Of Canine Behavioural Traits In Historical Us Demand For Dog Breeds (1926–2005), Bethany Wilson, James Serpell, Harold Herzog, Paul Mcgreevy

Demography and Statistics for Companion Animal Populations Collection

Drawing on American Kennel Club (AKC) puppy registration numbers for approximately 82 varieties of pedigree dogs between 1926 and 2005, the current article analyses behavioural reports on 32,005 dogs of these varieties reported through the Canine Behavioural Assessment and Research Questionnaire (C-BARQ). Cluster analysis of C-BARQ scores indicates that the 82 breeds fell into six clusters. Average scores for each of the 14 behavioural subscales and 22 miscellaneous traits in C-BARQ were calculated for each cluster, and the breeds in each cluster with average scores most similar to the cluster averages were selected as titular breeds. Titular breeds for each …

November/December 2018, Issue 4, James Madison University Uhc Marketing Team

Potty Mouth

No abstract provided.

November 1, 2018, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Native Elder And Youth Perspectives On Mental Well-Being, The Value Of The Horse, And Navigating Two Worlds, Mary J. Isaacson, Rebecca Bott-Knutson, Mary Beth Fishbeck, Angela Varnum, Shelly Brandenburger

College of Nursing Faculty Publications

Purpose: Native American youth experience significant challenges to mental well-being. As part of a larger study to evaluate hope and resilience in a Plains tribal population, the purpose of this study was to learn from Native American elders and youths what they feel is needed to for youth to grow up healthy on the reservation, and to identify connections between horse use and mental well-being.
Sample: Six Native American elders and eight Native American youths from the same Plains tribe.
Method: The research team conducted Talking Circles with youths and elders. during the Talking Circles, participants identified community-specific questions for …

Querying Rural Content Experts Using An Online Questionnaire, Marilyn A. Swan, Barbara B. Hobbs

College of Nursing Faculty Publications

Purpose: Obtaining feedback from rural content experts is critical in developing valid and reliable instruments to advance the science of rural health. However, traditional methods, i.e., focus groups are impractical due to location and distance. Using an online questionnaire combined with telephone and email contacts to obtain content experts’ feedback is discussed. Item statement analysis and efficiency and effectiveness of the process are presented.
Methods: The process included the development of an online questionnaire, asking experts to rate 51 item statement for their relevancy, sufficiency of description, and clarity and readability. To increase the response rate, a series of four …

Differences In Physical Activity And Diet Patterns Between Non-Rural And Rural Adults., Lacey Mccormack, Howard Wey, Jessica R. Meendering, Bonny Specker

Health and Nutritional Sciences Faculty Publications

BACKGROUND: It is unclear how rural occupations and lifestyles may play a role in shaping physical activity and diet behaviors that contribute to the rural⁻urban obesity disparity.
METHODS: Data come from the prospective and observational South Dakota Rural Bone Health Study, which included adults aged 20⁻66 years in three groups: (1) non-rural non-Hutterite, (2) rural non-Hutterite, and (3) rural Hutterite. Physical activity data were collected using 7-day physical activity questionnaires, and hours per day in physical activity categories are reported. Diet data were collected using food frequency questionnaires, and food group servings per day (svg/day) are reported. Mixed models were …