Digital Commons Network^™

Dual-Display Laparoscopic Laser Speckle Contrast Imaging For Real-Time Surgical Assistance, Jaepyeong Cha, Corey Zheng, Lung Wai Lau

Pediatrics Faculty Publications

Laser speckle contrast imaging (LSCI) utilizes the speckle pattern of a laser to determine the blood flow in tissues. The current approaches for its use in a clinical setting require a camera system with a laser source on a separate optical axis making it unsuitable for minimally invasive surgery (MIS). With blood flow visualization, bowel viability, for example, can be determined. Thus, LSCI can be a valuable tool in gastrointestinal surgery. In this work, we develop the first-of-its-kind dual-display laparoscopic vision system integrating LSCI with a commercially available 10mm rigid laparoscope where the laser has the same optical axis as …

Cseas Weekly Bulletin (November 5, 2018), Center For Southeast Asian Studies

CSEAS Bulletin

No abstract provided.

Faculty Senate Agenda And Minutes, November 5, 2018

Faculty Senate Minutes and Agendas

Agenda and minutes from the Wright State University Faculty Senate Meeting held on November 5, 2018.

Influence Of Crossbreeding On Meat Goat Doe Fitness When Comparing Boer F1 With Base Breeds In The Southeastern United States, Piush Khanal, Maria L. Leite-Browning, Richard Browning Jr.

Agricultural and Environmental Sciences Faculty Research

Understanding fitness level among various breeds is essential for sustainable meat goat production. Research on the relative fitness of Boer F₁ does and straightbred base breed has been limited. Meat goat does of various genotypes (Boer, Kiko, Spanish, Boer × Kiko reciprocal F₁ crosses, and Boer × Spanish reciprocal F₁ crosses) were studied to evaluate breed effects on doe fitness traits and the expression of heterosis over 7 production years. The herd was semi-intensively managed under humid subtropical pasture. Doe age affected (P < 0.05) various traits. Boer × Kiko does were heavier (P < 0.05) than Boer does at fall breeding, but Boer × Spanish does did not differ (P > 0.05) from Boer does for breeding weight. The body weights of …

Ada News - 11/05/2018, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Lanthorn, Vol. 53, No. 12, November 5, 2018, Grand Valley State University

Volume 53, July 9, 2018 - June 10, 2019

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

Kinetic Characterization Of The Shigella Type Three Secretion System Atpase Spa47 Using Α-32p Atp, Heather B. Case, Nicholas E. Dickenson

Chemistry and Biochemistry Faculty Publications

ATPases represent a diverse class of enzymes that utilize ATP hydrolysis to support critical biological functions such as driving ion pumps, providing mechanical work, unfolding/folding proteins, and supporting otherwise thermodynamically unfavorable chemical reactions. We have recently shown that the Shigella protein Spa47 is an ATPase that supports protein secretion through its specialized type three secretion apparatus (T3SA), supporting infection of human host cells. Characterizing ATPases, such as Spa47, requires a means to accurately determine enzyme activity (ATP hydrolysis) as a function of time, reaction conditions, and potential cofactors, regulators, inhibitors, etc. Here, we describe a detailed protocol for characterizing …

The Statesman, V. 62, I. 10, Stony Brook University

Stony Brook Statesman-Sucolian

v. 62, i. 10;

Hlc Accreditation Final Report - November 2018, University Of Missouri-St. Louis

UMSL Accreditation

No abstract provided.

Sediment Dynamics In The Bear River-Mud Lake-Bear Lake System, Patrick Belmont, Mitchell Donovan, Janice Brahney, Lindsay Capito, Zach Burgert

Watershed Sciences Faculty Publications

The overarching goal of this project was to compile and analyze a variety of existing datasets, and generate several new datasets, to advance our understanding of how the Bear River Mud Lake-Bear Lake system functions, how it has, or is expected to change, identify which components are degraded or vulnerable to degradation, and determine if/where critical data and/or knowledge gaps exist. We conducted a series of analyses to evaluate changes in hydrology and suspended sediment, collected sediment cores from nine locations in Mud Lake to evaluate how sedimentation rates, sediment sources and water quality have changed over time, and utilized …

Grand Valley Forum, Volume 043, Number 06, November 5, 2018, Grand Valley State University

2018-2019, Volume 43

Grand Valley Forum is Grand Valley State's faculty and staff newsletter, published from 1976 to the present.

Faculty Senate Agenda, November 5, 2018, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• Faculty Forum - November 12, 2018
• EPC Monthly Report - October 4, 2018
• Libraries Advisory Council Annual Report
• Code 405.11.4 (External Reviewers)
• Proposal to Develop USU Greenhouse Gas Emissions Resolution

What's Happening: November 5, 2018, Maine Medical Center

What's Happening

No abstract provided.

Unh Initiative Will Help Meet The Demand For Addiction Treatment In The State, Erika Mantz

Media Relations

No abstract provided.

Tri-Ponderal Mass Index In Survivors Of Childhood Brain Tumors: A Cross-Sectional Study., E Danielle Sims, Kuan-Wen Wang, Adam Fleming, Donna L Johnston, Shayna M Zelcer, Shahrad Rod Rassekh, Sarah Burrow, Lehana Thabane, M Constantine Samaan

Paediatrics Publications

Survivors of childhood brain tumors (SCBT) face a higher risk of cardiometabolic disorders and premature mortality compared to the general population. Excess adiposity is a known risk factor for these comorbidities. However, while SCBT have higher adiposity compared to healthy controls, measuring adiposity in clinical practice involves access to specialized equipment and may impact busy clinical services. Tri-ponderal Mass Index (TMI; kg/m

20181105_Get Real- Vr Lab Now Accepting Reservations, Laura J. Hall

HSLIC Blog Post

No abstract provided.

Application Of Click Chemistry In The Development Of Peptide Based Hiv Fusion Inhibitors, Mukesh Madan Mudgal, Nagaraju Birudukota

Chemistry and Physics Faculty Articles

Human Immunodeficiency Virus (HIV) continues to be a major global public health issue. Inhibition of HIV envelope fusion with the CD4 cell membrane prevents the entry of HIV into the CD4 cells providing a novel approach to the treatment of HIV infection. Thus, interference in the fusion of the virus with the co-receptor substrate appears to be a specific and potential way to fight HIV infection and replication. Applications of click chemistry are spreading in the field of drug discovery and it became a powerful tool for the synthesis of medicinally important compounds.

Remarkably, the Cu (I)-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) …

Impact Of Precision Medicine On Drug Repositioning And Pricing: A Too Small To Thrive Crisis, Venkataswarup Tiriveedhi

Biology Faculty Research

The pricing of targeted medicines continues to be a major area of contention in healthcare economics. This issue is further complicated by redefining the role of molecular testing in precision medicine. Currently, whilst pricing of clinical laboratory diagnostics is cost-based, drug pricing is value-based. The pricing for molecular testing is under pressure to change the traditional business model, for it has a critical subsidiary role in determining the final value of targeted medicines. The market size for drugs is reduced by molecular testing when patients with the same disease are stratified based on their genetics, it is critical to determine …

A Call For Nominations, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Rotunda - Vol 97, No. 10 - Nov 5, 2018, Longwood University

Rotunda

No abstract provided.

The Daily Gamecock, Monday, November 5, 2018, University Of South Carolina, Office Of Student Media

November

No abstract provided.

Role Of Noise And Parametric Variation In The Dynamics Of Gene Regulatory Circuits., Vivek Kohar, Mingyang Lu

Faculty Research 2018

Stochasticity in gene expression impacts the dynamics and functions of gene regulatory circuits. Intrinsic noises, including those that are caused by low copy number of molecules and transcriptional bursting, are usually studied by stochastic simulations. However, the role of extrinsic factors, such as cell-to-cell variability and heterogeneity in the microenvironment, is still elusive. To evaluate the effects of both the intrinsic and extrinsic noises, we develop a method, named sRACIPE, by integrating stochastic analysis with random circuit perturbation (RACIPE) method. RACIPE uniquely generates and analyzes an ensemble of models with random kinetic parameters. Previously, we have shown that the gene …

A Randomized Control Trial Of Anti-Inflammatory Regional Hypothermia On Urinary Continence During Robot-Assisted Radical Prostatectomy., Linda M Huynh, Douglas Skarecky, James R Porter, Christian Wagner, Jorn Witt, Timothy Wilson, Clayton Lau, Thomas E Ahlering

Articles, Abstracts, and Reports

The present study seeks to present a single-blind, randomized control trial of a hypothermic anti-inflammatory device, the endorectal cooling balloon (ECB), to assess whether regional hypothermia could improve 90-day and time to pad-free continence following robot-assisted radical prostatectomy (RARP). Five high-volume surgeons at three institutions had patients randomized (1:1) to regional hypothermia with ECB versus control. Patients were blinded to device use, as it was inserted and removed intraoperatively. Knowledge of device use was restricted to the operating room personnel only; recovery room and ward nursing staff were not informed of device use and instructed to indicate such if a …

2018-November-5-Linkedin Workshop, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY (Nov. 28, 2018) – A graduate of the Bill Gatton College of Pharmacy at East Tennessee State University has been appointed to one of the highest pharmacy positions in Tennessee.

Gov. Bill Haslam requested Dr. Melissa McCall, of Kingsport, to serve on the Tennessee Board of Pharmacy for the next six years. McCall is a 2010 graduate of the Gatton College of Pharmacy’s inaugural class.

“I am honored and humbled to serve the state in this capacity and look forward to helping the Tennessee Department of Health fulfill its mission to protect, promote and improve the health and …

Kinetics Of Dextromethorphan-O-Demethylase Activity And Distribution Of Cyp2d In Four Commonly-Used Subcellular Fractions Of Rat Brain, Barent N. Dubois, Farideh Amirrad, Reza Mehvar

Pharmacy Faculty Articles and Research

The purpose of this study was to compare the enzymatic kinetics and distribution of cytochrome P450 2D (CYP2D) among different rat brain subcellular fractions.

Rat brains were used to prepare total membrane, crude mitochondrial, purified mitochondrial, and microsomal fractions, in addition to total homogenate. Michaelis–Menten kinetics of the brain CYP2D activity was estimated based on the conversion of dextromethorphan (DXM) to dextrorphan using UPLC-MS/MS. Protein levels of CYP2D and subcellular markers were determined by Western blot.

Microsomal CYP2D exhibited high affinity and low capacity, compared with the mitochondrial CYP2D that had a much lower (∼50-fold) affinity but a higher (∼six-fold) …

The Rider (2018-11-05), Victor G. Ramirez

The Rider Archives

Vol.4 No.11

National Security, Immigration And The Muslim Bans, Shoba Sivaprasad Wadhia

Washington and Lee Law Review

No abstract provided.

Medical Migration As Access To Health Care In The Rio Grande Valley, Rosalynn A. Vega

Anthropology Faculty Publications

This qualitative research explains difficulties among migrants when accessing health care. Many individuals of Mexican origin either travel to more accessible health care in Mexico or arrange to have medical services and pharmaceuticals transported to them in the United States. The research is based in a majority Hispanic and Spanish-speaking county in the US which is characterized by a high degree of poverty and illness, especially diabetes (Melo 2017, Montoya 2011). This article provides an ethnographic approach to medical migration and describes the importance of medical migration for both Mexico and the United States. The article offers recommendations for public …

Unh Research Finds Pay-As-You-Throw Trash Policies Cut Solid Waste Disposal, Lori Tyler Gula

Media Relations

No abstract provided.

What Conditions Enable Decentralization To Improve The Health System? Qualitative Analysis Of Perspectives On Decision Space After 25 Years Of Devolution In The Philippines, Harvy Joy Liwanag, Kaspar Wyss

Ateneo School of Medicine and Public Health Publications

Background

Decentralization is promoted as a strategy to improve health system performance by bringing decision-making closer to service delivery. Some studies have investigated if decentralization actually improves the health system. However, few have explored the conditions that enable it to be effective. To determine these conditions, we have analyzed the perspectives of decision-makers in the Philippines where devolution, one form of decentralization, was introduced 25 years ago.

Methods

Drawing from the “decision space” approach, we interviewed 27 decision-makers with an average of 23.6 years of working across different levels of the Philippine government health sector and representing various local settings. …