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2018

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Ccl11 As A Biomarker For The In Vivo Diagnosis Of Chronic Traumatic Encephalopathy, Robert Weissenfels Jan 2018

Ccl11 As A Biomarker For The In Vivo Diagnosis Of Chronic Traumatic Encephalopathy, Robert Weissenfels

CMC Senior Theses

Chronic traumatic encephalopathy is the neurodegenerative disease that is ascribed to the long term development of cognitive, behavioral, emotional, and motor deficits as a result of the exposure to high amounts of sub concussive traumatic brain injuries. The disease has gained recent popularity in the media for its prevalence in American football as a response to recent research that has suggested the prominence of the disease in nearly every NFL player that is examined post mortem. This has produced a growing concern for the consequences of head impact and participation in contact sports. Despite media attention, little is currently known …


Hyperthermia As A Cancer Treatment- From Theory To Practice, Graham Fullerton Jan 2018

Hyperthermia As A Cancer Treatment- From Theory To Practice, Graham Fullerton

CMC Senior Theses

Using iron super-paramagnetic and ferromagnetic nanoparticles composed of Fe3O4 molecules, scientists analyze the effectiveness and practicality of this new treatment theory, hyperthermia. The problems of magnetic particle density, isothermal barriers/cellular cooling thresholds, and nanoparticle specific targeting are addressed in this review.

Iron magnetic nanoparticles were chosen due to their relatively low biological reactivates and lack of subsequent cellular toxicity. However, there are significant heating problems associated with these magnetic nanoparticles due to their relative size and short thermal time constants or thermal half-lives. Effectively, these aforementioned issues create a phenomenon where cancerous cells, surrounded by unheated healthy …


Crispr-Cas9 Mediated Hmgcl Ko In 3xtg Ad Mice Reduces The Cognitive Deficit Improvement Seen In An Intermittent Metabolic Switching Regimen, Eric Joon Bum Kil Jan 2018

Crispr-Cas9 Mediated Hmgcl Ko In 3xtg Ad Mice Reduces The Cognitive Deficit Improvement Seen In An Intermittent Metabolic Switching Regimen, Eric Joon Bum Kil

CMC Senior Theses

Individuals in modern Western societies are experiencing increasing sedentary lifestyles, overindulgence of high fat, high-sugar diets, and extremely sterilized conditions, putting immense pressure on researchers and clinicians alike to come up with viable treatments for conditions implicated with an aging society. Emerging research have published the benefits of IMS and metabolic switching in a variety of neuroprotective, cellular stress resistance, and neuroplasticity pathways in animal models and clinical results from randomized trials of IMS regimens with susceptible human populations are soon to be published. The application of genome editing and next-generation sequencing (NGS) strategies to clinical and neurodegenerative research continues …


Human Development And Subnationalism: A Disaggregated Analysis Of Indian States: Kerala And Uttar Pradesh, Manika Garg Jan 2018

Human Development And Subnationalism: A Disaggregated Analysis Of Indian States: Kerala And Uttar Pradesh, Manika Garg

CMC Senior Theses

This thesis investigates achievements in human development outcomes on health, education, and poverty indicators across Indian states, in order to discern what factors might influence a state’s better orientation toward social policies. After conducting data analysis, the study explains differences in outcomes, as achieved by Kerala and Uttar Pradesh, by building an argument of subnational solidarity and its impact on determining the state’s policy agendas.


Making Money And Making Change: Understanding And Overcoming Tension Between Profits And Purpose Within Social Entrepreneurship, Elijah H. Etzioni Jan 2018

Making Money And Making Change: Understanding And Overcoming Tension Between Profits And Purpose Within Social Entrepreneurship, Elijah H. Etzioni

CMC Senior Theses

Using a combination of interviews of social entrepreneurs and secondary research, this paper investigates the strategies that social entrepreneurs use to overcome tension and conflict between the two distinct goals of financial sustainability and mission fulfillment. The results suggest that although some social entrepreneurs can simultaneously achieve revenue generation and mission fulfillment, thus almost entirely eliminating any tension or misalignment, it is the creative responses of social entrepreneurs who have achieved one of these objectives and are attempting to achieve the other that prove the unique value of the practice. Additionally, the results gesture towards the conclusion that different kinds …


The Effect Of International Ngos On Influencing Domestic Policy And Law, Ashley Macarchuk Jan 2018

The Effect Of International Ngos On Influencing Domestic Policy And Law, Ashley Macarchuk

CMC Senior Theses

This thesis attempts to understand the impact of international human rights and environmental NGOs on affecting domestic policy and law. In particular, it looks at how State-NGO relations, civil society, and accountability affect the success of international NGOs in enacting change in domestic policy. The focus is on four countries with some of the largest human rights and environmental abuses: Argentina, China, India, and Russia. Through these countries, this thesis shows that NGOs have the most influence when State-NGO relations are strong, civil society is active, and NGOs are accountable to both the State and citizens. A key component to …


Reaching The Unreached: The Role Of Information Communication Technologies On Agency Of Women In India, Suvena Yerneni Jan 2018

Reaching The Unreached: The Role Of Information Communication Technologies On Agency Of Women In India, Suvena Yerneni

CMC Senior Theses

In this paper, I analyze the impact of Information Communication Technologies (ICTs) on female empowerment in India. In defining female empowerment, I consider the three dimensions of agency: social autonomy, economic autonomy, and mobility. Using nationally-representative data of 2012 from the Indian Human Development Survey (IHDS), I find that these information communication technologies, measured by ownership and use, have positive and significant impacts on female agency and decision-making abilities. I extend my analysis to two types of media: computers and mobile phones. These results persist even after accounting for the effects of education, income, and age of women.


The Two Conversions Of John Newton: Politics & Christianity In The British Abolitionist Movement, Megan Keller Jan 2018

The Two Conversions Of John Newton: Politics & Christianity In The British Abolitionist Movement, Megan Keller

CMC Senior Theses

This thesis interrogated the relationship between abolition and the evangelical revival in Britain through the life of John Newton. Newton, though not representative of every abolitionist, was a vital figure in the movement. His influence on Hannah More and William Wilberforce along with his contributions to the Parliamentary hearings made him a key aspect of its success. How he came to fulfill that role was a long and complex journey, both in terms of his religion and his understanding of slavery. He began his life under the spiritual direction of his pious, Dissenting mother, became an atheist by nineteen, and …


Rehumanize The Terrorist: Comparing The Depiction Of Terrorists In Academic Theory And Contemporary Fiction, Isabel Lilles Jan 2018

Rehumanize The Terrorist: Comparing The Depiction Of Terrorists In Academic Theory And Contemporary Fiction, Isabel Lilles

CMC Senior Theses

This thesis aims to respond to the following question: How does the depiction of terrorists in popular fiction novels compare to the explanations in academia as to why individuals become terrorists and join terrorist organizations? Is this fictional depiction a reflection or distortion of reality, and what insights can we take away from this comparison? The argument of this thesis is that fiction’s depiction of terrorists is both a reflection and distortion of reality, as it presents a unique creative, emotionally resonant narrative that humanizes the terrorists. By giving a voice to their motivations and experiences, readers are able to …


Stressed Out And Fed Up: The Effect Of Stress On Maternal Feeding Behaviors And The Moderating Role Of Executive Functioning, Isabel Mendiola Jan 2018

Stressed Out And Fed Up: The Effect Of Stress On Maternal Feeding Behaviors And The Moderating Role Of Executive Functioning, Isabel Mendiola

CMC Senior Theses

Stress is associated with a range of unhealthy eating habits. However, no previous studies have used experimental design to take an intergenerational perspective in the examination of how stress may influence parental feeding behavior, nor have they examined potential protective factors. The current study tests the effects of stress on maternal feeding behaviors and explores the potential protective role of maternal executive functioning (EF). We manipulated maternal stress with the Trier Social Stress Task (TSST) in a community sample mothers (N = 61, Mage = 33.45 years). We measured maternal EF with a series of computerized tasks. Maternal …


Institutional Ownership In Relation To The Mandatory Audit Firm Rotation Rule And Its Effect On Audit Quality, Latisha Shah Jan 2018

Institutional Ownership In Relation To The Mandatory Audit Firm Rotation Rule And Its Effect On Audit Quality, Latisha Shah

CMC Senior Theses

Previous studies have concluded that mandatory audit firm rotation (MAFR) has not been successful in controlling the outcomes of the auditor-client relationship. Additionally, the literature concludes that high institutional ownership enhances audit quality through monitoring the management-auditor relationship. This paper hypothesizes that better corporate governance in terms of high institutional ownership percentage will enhance audit quality during a MAFR regime. Since countries that have implemented MAFR in the past have their data in their local languages, I use the special case of Arthur Andersen clients based in the US as my treatment group. I carry out a descriptive statistical analysis …


Learning To Live And Love Virtuously, Henry Deruff Jan 2018

Learning To Live And Love Virtuously, Henry Deruff

CMC Senior Theses

John Stuart Mill and Immanuel Kant authored two of the most famous pieces of work in ethical theory (Utilitarianism and Groundwork of the Metaphysics of Morals, respectively), yet both fail for various reasons to give us direction by way of living good lives. This thesis begins by outlining those shortcomings, before offering Aristotelian virtue ethics as the solution. Virtue ethics, as conceived by Aristotle, Alasdair MacIntyre, and Julia Annas, delineates a process – grounded in our real lives – by which we may improve as people and therefore flourish, or live good, moral lives: the habituation of the …


The Economic Implications Of Nba Player Achievements On Athletic Apparel Companies, Paul Andrew Maddock Ii Jan 2018

The Economic Implications Of Nba Player Achievements On Athletic Apparel Companies, Paul Andrew Maddock Ii

CMC Senior Theses

This paper aims to measure the economic impact of different NBA player achievements on the athletic apparel companies, Nike, Adidas, and Under Armour. It looks at players affiliated with the brands who participated in three different events in the NBA from from 2007 to 2017: the All-Star game, the All-NBA awards, and starting lineups in the Finals. Monthly stock returns for each company were calculated for the months the events took place: January, February, May, and June. The return of each company was then regressed on total number of players each company had in the events. Four total regressions were …


Adapting To The Changing Tide: An Evaluation Of California’S Drought Policies And Future Mitigation Strategies, Lauren Dorsey Jan 2018

Adapting To The Changing Tide: An Evaluation Of California’S Drought Policies And Future Mitigation Strategies, Lauren Dorsey

CMC Senior Theses

California endured an extreme and prolonged drought from 2012 until the winter of 2017, offering a fascinating yet tragic example of how drought impacts lives. Despite this recent and stark phenomenon, there is surprisingly little information about its effects and implications. This thesis aims to lessen this knowledge gap by asking how severe the drought was, how well the state responded, and what policies would increase California’s water security. It answers these questions by exploring the Golden State’s long and complicated water management history, which is necessary to understand the current drought policy framework; then, it collects the emerging literature …


21st Century Film Criticism: The Evolution Of Film Criticism From Professional Intellectual Analysis To A Democratic Phenomenon, Asher Weiss Jan 2018

21st Century Film Criticism: The Evolution Of Film Criticism From Professional Intellectual Analysis To A Democratic Phenomenon, Asher Weiss

CMC Senior Theses

Film criticism has changed since its inception and will continue to change moving forward. The evolution of film criticism has largely been a story of the shift from an elite field of intellectual exploration by a few knowledgeable experts to a democratic phenomenon where expert analysis is aggregated and averaged, and the lines are blurred between true expertise and the random opinions of the masses. This paper will address the transition from the birth of film criticism to its popularization through the 90s, to what it has become today. By exploring the nature of film criticism historically and reviewing the …


The Effect Of The Change In Call Loan Rates And Volatility On Stock Returns In 1929: An Empirical Study Into A Determinant Of The Great Depression, Amberish Chitre Jan 2018

The Effect Of The Change In Call Loan Rates And Volatility On Stock Returns In 1929: An Empirical Study Into A Determinant Of The Great Depression, Amberish Chitre

CMC Senior Theses

I investigate the effect of the change in call loan rates on stock returns during 1929. Call loan rates are the interest rates on borrowed funds to trade equity on a given exchange. It is estimated that 40% of stocks during this period were bought on margin. After a price decline comes a margin call, followed by a forced sales of securities, which leads to additional margin calls and future price declines. I regress daily excess returns on the change in daily call loan rates during 1929. In addition, I estimate volatility using an ARCH model and observe the previously …


Effects Of Learned Exercises On Gross Motor Coordination In Children With Asd, Garrett Myers Jan 2018

Effects Of Learned Exercises On Gross Motor Coordination In Children With Asd, Garrett Myers

CMC Senior Theses

The effectiveness of a teaching progression to teach three “Olympic” exercises and improve gross motor coordination was evaluated with four children (3 boys, 1 girl) diagnosed with autism spectrum disorder (ASD). A multiple baseline design across children and within children across activities was used to evaluate the effectiveness of the teaching progression used to teach the physical exercise program, which consisted of three “Olympic” events (long jump, 50 foot dash, and a relay race). Results showed all four participants learned the three “Olympic” exercises, with all four participants mastering at least one of the three exercises. Two participants mastered all …


Perceived Social Support And Suicide-Related Depression Symptom Clusters Among Queer College Students, John Kellerman, Daniel Krauss Jan 2018

Perceived Social Support And Suicide-Related Depression Symptom Clusters Among Queer College Students, John Kellerman, Daniel Krauss

CMC Senior Theses

LGBTQ+ individuals report disproportionately high rates of depression and suicidal behaviors compared to the general populations, particularly among queer youth. Certain depressive symptoms and symptom clusters, namely hopelessness and self-blame, are predictive of suicidal behavior and outcomes. In contrast, perceived social support may act as a buffer against suicide ideation. The disparity in the rate of queer suicidality may be predicted by higher rates of hopelessness and self-blame, as well as lower rates of perceived social support among depressed queer youth in comparison to depressed non-queer youth. The current study will test this hypothesis using a sample of depressed queer …


Climate And Crime: Examining The Relationship Between Extreme Weather Events And Crime Rates In The United States, Erin Tully Jan 2018

Climate And Crime: Examining The Relationship Between Extreme Weather Events And Crime Rates In The United States, Erin Tully

CMC Senior Theses

This study attempts to determine whether there is a relationship between extreme weather events and crime rates. Due to the increasing effects of climate change, it is critical we understand the societal effects of extreme weather. Here, a panel data fixed effects regression was used to analyze state and year level data. It was hypothesized that there would be a relationship between crime and extreme events, but the results did not show a statistically significant relationship. Further research with increased geographic and temporal controls is encouraged.


Using Renewable Energy To Increase Tribal Sovereignty: A Feasibility Study For A Biomass Energy Plant On The Cocopah Reservation, Lauren Katrina D'Souza Jan 2018

Using Renewable Energy To Increase Tribal Sovereignty: A Feasibility Study For A Biomass Energy Plant On The Cocopah Reservation, Lauren Katrina D'Souza

CMC Senior Theses

Native American reservations in the United States are often located on mineral-rich lands, making them a target for fossil fuel development in already socioeconomically disadvantaged areas. As environmentally damaging as they are, coal and oil industries can bring invaluable jobs and money to isolated reservations, causing tribes to rely on fossil fuels for mere economic survival. In these instances of corporations or the federal government exploiting Native American labor and land, tribes lose the most fundamental principle of tribal governance: tribal sovereignty. Replacing fossil fuels and securing energy independence with a stable, renewable energy source is key to reclaiming that …


The Balance Between Financial And Quality Performance In For-Profit Hospitals Versus Non-Profit Hospitals, Blake Seidner Jan 2018

The Balance Between Financial And Quality Performance In For-Profit Hospitals Versus Non-Profit Hospitals, Blake Seidner

CMC Senior Theses

Recent trends of financial distress for non-profit hospitals and the uptick in acquisition of these hospitals by for-profit entities indicate different focuses from the management of each type of hospital. Using data on hospital quality and basic financial measures, this study examines shift in the balance of financial and quality performance. The dataset focuses on private non-profit and for-profit hospitals with low bed counts, ranging from 50-200 total beds. Results indicate a positive relationship between for-profit status and basic financial performance measures, such as profitability, and a negative relationship with patient experience, cost reduction for the patient, and overall quality. …


Examining The Roles Of Motivation And Parental Support In Division Iii College Sports: Understanding Leadership Emergence, Daniel King Jan 2018

Examining The Roles Of Motivation And Parental Support In Division Iii College Sports: Understanding Leadership Emergence, Daniel King

CMC Senior Theses

Self-determination theory states that people need autonomy, competence, and relatedness in an area to facilitate intrinsic motivation and growth. Parents play a major role in the development of these three psychological needs. The current study examines whether there is a relationship between parental behavior and whether this relationship is mediated by autonomy, competence and relatedness in their sport. Undergraduate participants (n=189) were recruited from varsity athletic teams and asked to complete surveys about perceived parental control and the three psychological needs. Results showed the parental behavior can predict satisfaction of psychological needs, but only one partial mediation was found, between …


Paid Parental Leave In The United States: Reconciling Competing Demands, Sydney Joseph Jan 2018

Paid Parental Leave In The United States: Reconciling Competing Demands, Sydney Joseph

CMC Senior Theses

The United States is the only developed nation that fails to provide its citizens with paid parental leave. The lack of parental benefit provision operates to the detriment of individuals and society as a whole by contributing to inequity across gender, race, socioeconomic status, and sexual orientation. As the demographics of the American workforce have changed, public policy has not kept pace. Paid parental leave is associated a number of health, economic, and social benefits. However, the greatest barrier to legislating paid parental leave is the philosophical underpinnings of American politics, specifically the strong current of liberal individualism and absence …


Rape And Sexual Violence Used As A Weapon Of War And Genocide, Larissa Peltola Jan 2018

Rape And Sexual Violence Used As A Weapon Of War And Genocide, Larissa Peltola

CMC Senior Theses

Rape and other forms of sexual violence have been used against civilian populations since the advent of armed conflict. However, recent scholarship within the last few decades proves that rape is not a byproduct of war or a result of transgressions by a few “bad apples,” rather, rape and sexual violence are used as strategic, systematic, and calculated tools of war, ethnic cleansing, and genocide. Rape has also been used as a means of preventing future generations of children of “undesirable” groups from being born. Rape and sexual violence are also used with the purpose of intimidating women and their …


Waterways - Soon Dry, Aiyanna Cameron-Lewis Jan 2018

Waterways - Soon Dry, Aiyanna Cameron-Lewis

CMC Senior Theses

This paper explores the historical and contemporary situation of waterways in Los Angeles. It examines the birth and growth of metropolitan LA and contrasts this narrative with the current and pressing issues of drought and gentrification. This contrast raises the question of the sustainability of human growth in resource-scarce regions. From this analysis it forwards a nuanced perspective of the hypothesis that the dynamics of environmental degradation in the LA region threaten human growth. It suggests that this degradation comes as a result of egocentric human development projects by the elite. This paper examines all of this through the lens …


Optimize Your Fitness, Optimize Your Business: The Balanced Scorecard, Analysis And Application For The Crossfit Affiliate, Jordan G. Aronowitz Jan 2018

Optimize Your Fitness, Optimize Your Business: The Balanced Scorecard, Analysis And Application For The Crossfit Affiliate, Jordan G. Aronowitz

CMC Senior Theses

The Balanced Scorecard for the CrossFit Affiliate will provide unprepared or inexperienced managers with the necessary information to make informed operational decisions. The Balanced Scorecard incorporates financial data, customer satisfaction, internal operations, and future growth to create a series of cause-and-effect relationships that illustrate how decisions in one aspect of a business affect others. The Balanced Scorecard particularly benefits inexperienced managers leading small businesses. As overall small business growth increased, the boutique fitness industry expanded. The CrossFit brand rose in conjunction, but because corporate leaders insist on a hands-off licensing model, affiliate owners do not receive assistance from CrossFit corporate …


The Influence Of Home Country Factors On Immigrant Entrepreneurship In The U.S., Kayalin Akens-Irby Jan 2018

The Influence Of Home Country Factors On Immigrant Entrepreneurship In The U.S., Kayalin Akens-Irby

CMC Senior Theses

This paper uses a Poisson regression model to determine the effects of entrepreneurial conditions of home countries on immigrant founded startup activity in the United States. The study determines that the most relevant factors are innovation, internal market dynamics, governmental support and policies, financing, and internal market openness. It then analyzes the change rates of these entrepreneurial conditions between 2007 and 2017 in China, India, and the United States to determine the implications of changing power dynamics in the global economy on flows of immigrant entrepreneurship and innovation in the global entrepreneurial ecosystem. The study finds that after being in …


Do The Lifetime Prevalence And Prognosis Of Schizophrenia Differ Among World Regions?, Cheryl Lynn Smith Jan 2018

Do The Lifetime Prevalence And Prognosis Of Schizophrenia Differ Among World Regions?, Cheryl Lynn Smith

CMC Senior Theses

Much cross-cultural research has been done on the topic of schizophrenia, but few studies thus far have focused on lifetime prevalence and prognosis together, grouped by world region. Additionally, there has been severe bias in which countries and regions have been studied both historically and currently. Any study that had statistics on lifetime prevalence per 1000 people and/or DALYs, from a specified country or region, was included in this thesis. Results showed that lifetime prevalence of schizophrenia does not differ among WHO regions, but DALYs and thus prognosis do differ. Several major conclusions can be drawn from these results. One …


The Politics Of U.S. Food Policy, Evan Murphy Jan 2018

The Politics Of U.S. Food Policy, Evan Murphy

CMC Senior Theses

Throughout the 20th century, American farmlands, agricultural policy, and diets have seen dramatic transformations. The number of farms in America has decreased, but the average size of farms has increased. These larger farms are increasingly more industrialized and produce a short list of profitable, subsidized commodity crops. Similarly, changes in the American diet throughout the 20th and 21st centuries have reflected these shifts in the landscape of American farmland. Simultaneous to the evolution of American farms was an increase in federal involvement in American agriculture through policy that seems to encourage these trends. Although separating out the causes from the …


Mindfulness Matters: The Effects Of Mindfulness On Organizational Citizenship Behavior, Rowan Mulligan Jan 2018

Mindfulness Matters: The Effects Of Mindfulness On Organizational Citizenship Behavior, Rowan Mulligan

CMC Senior Theses

Both mindfulness and authentic leadership base themselves on self-awareness. Authentic leadership has positively predicted organizational citizenship behavior (OCB), and mindfulness has been positively correlated to work engagement, which has shared positive relationships with OCB. Job demands (JD) have been shown to compromise work engagement. Using a sample of 134 MBA and undergraduate students, a longitudinal design evaluated the meditational role of authentic functioning (AF) between mindfulness and OCB and the moderating role of JD. Over the course of three months, three questionnaires were administered to measure mindfulness, AF, OCB, and JD. Despite the positive predictive relationship between mindfulness and AF, …