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On The Intersection Of Health, Well-Being, And Youth Development, Mary Elizabeth Arnold, Theresa Ferrari

Journal of Youth Development

This introduction sets forth forth the thinking that guided the journal’s special issue on youth health and well-being. Three main points provide the foundation: (a) that youth development is predicated on a strengths-based approach, (b) that an ecological approach to youth health is essential for real and lasting change, and (c) that the larger intent of youth development is encompassed in increasing youth well- being, of which youth health is a key component. The guest editors provide an overview of the articles included in the special issue. The articles highlight different settings, describe the processes involved in developing programs, and …

Feasibility And Fit Of A Mental Health Promotion Program For Lgbtq+ Youth, Alicia Lapointe, Caely Dunlop, Claire Crooks

Journal of Youth Development

This study evaluated the feasibility and fit of a mental health promotion and violence prevention program adapted for LGBTQ+ youth (ages 14-18). The pilot program included 16 30-minute sessions and was implemented in 8 gender and sexuality alliances (GSAs) and one community youth group setting. Extensive feedback was collected from 11 facilitators via session tracking sheets, ongoing email communication, an implementation survey, and a focus group; and from 7 youth who participated in a variety of feedback activities during a 2-day post-program workshop. Results indicated a strong interest in formalized programming, challenges related to its delivery in GSAs, and significant …

Detecting Significant Genotype–Phenotype Association Rules In Bipolar Disorder: Market Research Meets Complex Genetics, René Breuer, Manuel Mattheisen, Josef Frank, Bertram Krumm, Ney Alliey Rodriguez

School of Medicine Publications

Background: Disentangling the etiology of common, complex diseases is a major challenge in genetic research. For bipolar disorder (BD), several genome-wide association studies (GWAS) have been performed. Similar to other complex disorders, major breakthroughs in explaining the high heritability of BD through GWAS have remained elusive. To overcome this dilemma, genetic research into BD, has embraced a variety of strategies such as the formation of large consortia to increase sample size and sequencing approaches. Here we advocate a complementary approach making use of already existing GWAS data: a novel data mining procedure to identify yet undetected genotype–phenotype relationships. We adapted …

Application Of A Hygroscopicity Tandem Differential Mobility Analyzer For Characterizing Pm Emissions In Exhaust Plumes From An Aircraft Engine Burning Conventional And Alternative Fuels, Max B. Trueblood, Prem Lobo, Donald E. Hagen, Steven C. Achterberg, Wenyan Liu, Philip D. Whitefield

Chemistry Faculty Research & Creative Works

In the last several decades, significant efforts have been directed toward better understanding the gaseous and particulate matter (PM) emissions from aircraft gas turbine engines. However, limited information is available on the hygroscopic properties of aircraft engine PM emissions which play an important role in the water absorption, airborne lifetime, obscuring effect, and detrimental health effects of these particles. This paper reports the description and detailed labbased performance evaluation of a robust hygroscopicity tandem differential mobility analyzer (HTDMA) in terms of hygroscopic properties such as growth factor (GF) and the hygroscopicity parameter (κ). The HTDMA system was subsequently deployed during …

Changes In Acceptance Of Dating Violence And Physical Dating Violence Victimization In A Longitudinal Study With Teens, Marie E. Karlsson, Maegan Calvert, Juventino Hernandez Rodriguez, Rebecca Weston, Jeff R. Temple

Psychological Science Faculty Publications

Teen dating violence is a pervasive issue in adolescence and has been linked to maladjustment (Temple, Shorey, Fite, et al., 2013). Physical dating violence is a particularly significant problem with one in five adolescents reporting experiencing physical teen dating violence (TDV; Wincentak et al., 2016). Acceptance of violence has been suggested to increase the risk of TDV; however, most studies to date have been cross-sectional. The purpose of the current study is to examine patterns of acceptance of dating violence and TDV victimization across time. Participants were ethnically diverse teenagers (N = 1,042; ages 13 – 18) …

Onward To Opportunity: A Case For Patient Philanthropy, Supporting Jobs And Careers For Military-Connected Americans, Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This paper details an exemplar case of partnership and philanthropic engagement, positioned to fundamentally transform the means and expectations associated with the employment transition experience for veterans. The vehicle for this transformation is an innovative transition initiative called Onward to Opportunity (O2O). The design, development, and evolution of the O2O program has been supported by early investment and prolonged commitment on the part of philanthropic partners—led by the Schultz Family Foundation—alongside close collaboration with JPMorgan Chase & Co. as well as other public sector and employer partners. These partnerships have, in turn, mobilized and empowered otherwise disparate stakeholders to come …

Enhancing Veterans' Access To Stem Education And Careers: A Labor Market Analysis Of Veterans In The Stem Workforce - Infographic, Rosalinda Maury, Brice M. Stone, Nicholas Armstrong

Institute for Veterans and Military Families

This research brief presents key highlights on recent veteran participation in the STEM workforce drawing upon an analysis of the American Community Survey (2012-2016), led by the U.S. Census Bureau. From this data, the research team examined veteran participation across 49 distinct STEM occupations, which are grouped into the following five occupational clusters: Engineering, Information Technology and Computer Science, Life and Physical Sciences, Mathematics, and Supervisor/ Management of STEM occupations. Among other analyses, the research team identified year-over-year trends in veteran participation, geographic distribution, and comparisons to non-veterans across all STEM occupations.

Haemoglobin: An Amenable Outcome Factor Of Acute Ischemic Stroke After Thrombolysis, Saumya H. Mittal, Rakshith Kc, Misri Zk, Shivanand Pai

Manipal Journal of Medical Sciences

Objective: To study the role of haemoglobin in outcome of thrombolysis after stroke. Material and method: Our observational study was conducted over five years at KMC Hospital, Mangalore from July 2011 to July 2016. All patients above the age of 18 years presenting to the hospital within 4.5 hours of onset of stroke were included into the study. The patients’ stroke severity was calculated by National Institute of Health Stroke Scale (NIHSS) score, while the outcome was measured by Modified Rankin Scale (mRS) score. The patients were divided into good outcome, poor outcome and expired group of patients depending on …

Genetic Variants Of The 11 Beta-Hydroxysteroid Dehydrogenase Type 1 Gene Influence Metabolic Syndrome, Nayana Devang, Kapaettu Satyamoorthy, Padmalatha S. Rai, Nandini M, Prabha Adhikari Dr

Manipal Journal of Medical Sciences

Background: Metabolic syndrome (metS) is the prominent public issue around the globe which contributes to several diseases, including type 2 diabetes, obesity, and insulin resistance (IR). At a recent time, IR due to cortisol excess has been implicated as part of metS etiology. The 11 beta- hydroxysteroid dehydrogenase type 1 (HSD11B1) gene that encodes 11 beta- hydroxysteroid dehydrogenase (11β-HSD1) enzyme has a pivotal role in maintaining serum cortisol level against IR. The aim of this study was to detect the frequency of HSD11B1 gene polymorphisms and their association with metS among the South Indian cohort. Methods: Our study included 613 …

Assessment Of Information Seeking Pattern And Evaluation Of The Degree Of Its Negativity In Influence - A Cross Sectional Study Among Adolescents Of Dakshina Kannada District, D’Cunha Delma, Prabhu H. Sudhir

Manipal Journal of Medical Sciences

Introduction: Adolescents are vulnerable group of individuals forming a significantly large proportion of the Indian population. In a bid to satisfy queries and curiosities, adolescents seek various sources for answers. The sources could be highly unreliable at times, but choice is largely made based on convenience and maintenance of anonymity. Aim and objectives: The study was aimed at assessing the sources of information sought by adolescents for various queries and also the impact it had on substance abuse. Methodology: A total of 222 adolescents (age range 10-19 years; mean age= 14.5years) were included in the study. A pre-structured and pretested …

Hand Hygiene And Its Implications In Health Care Associated Infections In A Tertiary Care Facility - A Questionnairebased Survey, Vishnu Kundoor Reddy, Abhimanyu Chatterjee, Sheffali Sharma, Nikhil Harish Chaturani, Chiranjay Mukhopadhyay

Manipal Journal of Medical Sciences

Background: Health care associated infections (HCAI) pose a serious threat, especially in developing countries. Hand washing is a proven and easily practiced technique for reducing HCAI. Aim: To measure the knowledge, attitude and practices of students and faculty in medical and paramedical fields in a tertiary care facility. Method: This cross sectional study was conducted using a Knowledge, Attitude and Practice (KAP) questionnaire constituting of 18 questions. The questionnaire was distributed to students and faculty of health care related colleges via online form resulting in 799 responses. Study population was divided into medical students, paramedical students and faculty subgroups Result: …

A Rare Neurological Infectious Manifestation: Remedy Accomplished Exquisitely, Amruta V. Rajamanya, Saumya H. Mittal, Shivananda Pai, Keerthiraj B, Misri Z K, Rohith Pai

Manipal Journal of Medical Sciences

A 23-year-old Indian male with infective endocarditis with embolic infarct was on IV antibiotics. One month later, he presented with convulsions without any significant focal deficit, CT revealed large intraparenchymal bleed, which on Digital Subtraction Angiogram (DSA) showed a leaking intracranial Mycotic Aneurysm (MA). Aneurysm was embolized using 62% histoacryl glue under roadmap guidance following which the leakage was stopped successfully. This case emphasizes the importance of considering the presence of MA in the differential diagnosis in the setting of suspected endocarditis and focal neurological deficits. Endovascular intervention and embolization with gluing is preferred for MA in view of friable …

Effects Of Novel Calpain Inhibitors In Transgenic Animal Model Of Parkinson's Disease/Dementia With Lewy Bodies, Getaw Hassen, Leo Kesner, Alfred Stracher, Abraham Shulman, Edward Rockenstein, Michael Mante, Eliezer Masliah

NYMC Faculty Publications

Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are neurodegenerative disorders of the aging population characterized by the accumulation of alpha-synuclein (alpha-syn). The mechanisms triggering alpha-syn toxicity are not completely understood, however, c-terminus truncation of alpha-syn by proteases such as calpain may have a role. Therefore, inhibition of calpain may be of value. The main objective of this study was to evaluate the effects of systemically administered novel low molecular weight calpain inhibitors on alpha-syn pathology in a transgenic mouse model. For this purpose, non-tg and alpha-syn tg mice received the calpain inhibitors - Gabadur, Neurodur or a vehicle, …

A 54-Year-Old Woman With Myelofibrosis And Massive Hemothorax Due To Primary Extramedullary Hematopoiesis Of The Pleura, Michael Karass, Katherine Linder, Anup Agarwal, Alexandra Budhai, Yasmin Yusuf, Oleg Epelbaum

NYMC Faculty Publications

No abstract provided.

Decreasing Mortality And Hospitalizations With Rising Costs Related To Gastric Cancer In The Usa: An Epidemiological Perspective, Delong Liu, Dhruv Mehta, Supreet Kaur, Arun Kumar, Kaushal Parikh, Lavneet Chawla, Aparna Saha

NYMC Faculty Publications

BACKGROUND: There is no convincing data on the trends of hospitalizations, mortality, cost, and demographic variations associated with inpatient admissions for gastric cancer in the USA. The aim of this study was to use a national database of US hospitals to evaluate the trends associated with gastric cancer. METHODS: We analyzed the National Inpatient Sample (NIS) database for all patients in whom gastric cancer (ICD-9 code: 151.0, 151.1, 151.2, 151.3, 151.4, 151.5, 151.6, 151.8, 151.9) was the principal discharge diagnosis during the period, 2003-2014. The NIS is the largest publicly available all-payer inpatient care database in the US. It contains …

Controversies About Lyme Disease-Reply, Eugene D. Shapiro, Gary P. Wormser

NYMC Faculty Publications

No abstract provided.

Evolution And Mutations Predisposing To Daptomycin Resistance In Vancomycin-Resistant Enterococcus Faecium St736 Strains, Guiqing Wang, Weihua Huang, Abhay Dhand, Changhong Yin, Marisa Montecalvo, Nevenka Dimitrova, John T. Fallon

NYMC Faculty Publications

We recently identified a novel vancomycin-resistant Enterococcus faecium (VREfm) clone ST736 with reduced daptomycin susceptibility. The objectives of this study were to assess the population dynamics of local VREfm strains and genetic alterations predisposing to daptomycin resistance in VREfm ST736 strains. Multilocus sequence typing and single nucleotide variant data were derived from whole-genome sequencing of 250 E. faecium isolates from 1994-1995 (n = 43), 2009-2012 (n = 115) and 2013 (n = 92). A remarkable change was noticed in the clonality and antimicrobial resistance profiles of E. faecium strains between 1994-1995 and 2013. VREfm sequence type 17 (ST17), the prototype …

Regional Tissue Oxygen Extraction And Severity Of Anemia In Very Low Birth Weight Neonates: A Pilot Nirs Analysis, Jonathan Mintzer, Boriana Parvez, Edmund F. La Gamma

NYMC Faculty Publications

Objective: Anemia causes blood flow redistribution and altered tissue metabolic behavior to sustain homeostatic oxygen consumption. We hypothesized that anemia severity would correlate with increased regional fractional tissue oxygen extraction among premature neonates.

Study Design: Regional oxygen extraction was calculated using pulse oximetry and near-infrared spectroscopy data among neonates

Results: Twenty-seven neonates with gestational age 27 ± 2 weeks and birth weight 966 ± 181 g underwent 116 hematocrit determinations. Cerebral and flank oxygen extraction inversely correlated with hematocrit (cerebral r = −0.527, p = 0.005; flank r = −0.485, p = 0.01). Increased cerebral oxygen extraction was observed for …

Understanding Environmental, Health And Economic Activity Interactions Following Transition Of Ownership In Gold Mining Areas In Tanzania: A Case Of Private To Public, Sophia Rhee, Elias Charles Nyanza, Madison Condon, Joshua Fisher, Theresia Maduka, Anja Benshaul-Tolonen

Faculty Scholarship

Mining is an important source of revenue for many developing countries, however, the social, environmental and economic impacts of mining are often poorly monitored. The recent transition of a gold mine in Western Tanzania—from large-scale gold mine under private, multinational ownership, to medium-scale public and national owned mine with limited life length offers a prime opportunity to understand the implications of changes in ownership and scale on the local economy and community well-being. We conducted 44 semi-structured interviews with community members in four villages adjacent to the mine site. We find that the local economy and public service provision contracted …

Assessing The Impact Of The Global Compacts On Refugees And Migration In The Middle East, Susan M. Akram

Faculty Scholarship

Today, the overwhelming burden of the global refugee and migrant crisis is borne by the Middle East region, driven by protracted armed conflict and exacerbated by a deficit of applicable international legal norms. Most States in the Middle East have not adopted the international treaties that provide protection guarantees for refugees and stateless persons, the 1951 Refugee Convention and its 1967 Protocol, the 1954 Convention on the Status of Stateless Persons, and the 1961 Convention on the Reduction of Statelessness. The lack of legal status for persons displaced by conflict, many of whom are stateless refugees, leaves them in situations …

Impact Of Sepsis And Non-Communicable Diseases On Prognostic Models To Predict The Outcome Of Hospitalized Chronic Liver Disease Patients, Fakhar Qazi, Shahab Abid, Preet Ayoub Shaikh, Safia Awan

Section of Gastroenterology

AIM: To evaluate the impact of sepsis and non-communicable diseases (NCDs) on the outcome of decompensated chronic liver disease(CLD) patients.

Methods: In this cross-sectional study, medical records of patients with CLD admitted to the Gastroenterology unit at the Aga Khan University Hospital were reviewed. Patients older than 18 years with decompensation of CLD (i.e., jaundice, ascites, encephalopathy, and/or upper gastrointestinal bleed) as the primary reason for admission were included, while those who were admitted for reasons other than decompensation of CLD were excluded. Each patient was followed for 6 wk after index admission to assess mortality, prolonged hospital …

True Colors: Crime, Race And Colorblindness Revisited, Itay Ravid

Faculty Publications

TRUE COLORS: CRIME, RACE AND COLORBLINDNESS REVISITED Itay Ravid* The violent, racially motivated events of the Charlottesville rally unleashed demons that many Americans believed were long buried. Old Jim Crow-inspired racism came straight through the front door. Yet critics of colorblind policies were not surprised. For them, such an eruption of racial hatred manifested what they had repeatedly argued: colorblind policies neither alter racial predispositions nor affect the unequal treatment of minorities in the United States. In fact, colorblindness has given rise to a modern, latent type of racism. This Article empirically investigates this claim in an unexplored context—the media’s …

Multi‐Modal Analysis Of Deciduous Tree Stands Toward Ash Tree Inventory: Biomass Estimation And Genus‐Level Discrimination In A Mixed Deciduous Forest, Timothy D. Rupright

Theses

The invasive species Agrilus planipennis (Emerald Ash Borer or EAB) is currently impacting ash trees in a large part of the continental United States. One way of measuring the effect of this infestation on the US markets is to determine the spread of the species and the biomass destruction/loss due to this invasive pest. In order to assess such impacts, it is necessary to determine how and where ash trees are located toward accurately measuring the relevant ash species biomass and tree count.

This study utilizes data captured over the campus of Rochester Institute of Technology in Rochester, NY. Hyperspectral …

Using Microalgae To Remediate Food And Bio-Digester Effluents From Western New York Agro Industries And Prospecting Harvested Algae Biomass For Biofuel Feedstocks, Daniel Anini Baah

Theses

Agro-industries of Western NY contributes to the US economy in diverse ways. Among these are dairy, poultry, cheese, tofu and Greek Yogurt plants whose processes discharge effluents high in pollutants such as NH3, PO4, NO3, and Fe which adversely affect aquatic systems and the watershed if discharged untreated. Waste hauling causes an economic burden to industries as WWTPs remain restrictive to these effluents, but Algae Remediation Technology provides a sustainable alternative to treating agricultural wastewaters onsite. This study sampled, assessed and treated effluents from selected production plants within NY State with various algae. The research applied free suspended Algae technology …

Effectiveness Of Prescribed Fire On Meeting Fuel Load And Wildlife Habitat Management Objectives In East Texas National Forests, Trey Wall

Electronic Theses and Dissertations

Using standardized methodology outlined by the United States Forest Service and the National Forests and Grasslands in Texas’ Fire Monitoring Program for data collection, the efficacy of current Forest Service prescribed burn regimes were analyzed for 24 study sites in East Texas National Forests. Study sites were located within Sam Houston, Davy Crockett, and Angelina/Sabine National Forests. Efficacy was determined by comparing defined management objectives established by the Forest Service to the data collected at the study sites. The results conclude that most objectives, as outlined by the Forest Service, are not being met with the current practices. Re-visitation of …

The Photometric Effect Of Macroscopic Surface Roughness On Sediment Surfaces, Greg Badura

Theses

The focus of this work was on explaining the effect of macroscopic surface roughness on the reflected light from a soil surface. These questions extend from deciding how to best describe roughness mathematically, to figuring out how to quantify its effect on the spectral reflectance from a soil’s surface. In this document, I provide a background of the fundamental literature in the fields of remote sensing and computer vision that have been instrumental in my research. I then outline the software and hardware tools that I have developed to quantify roughness. This includes a detailed outline of a custom "LiDAR" …

Glimmer, Cody Barron

Theses

Glimmer is a 3D animated graduate thesis film that is 4 minutes long. The film is a gag-based comedy that sets out to emulate the style of early Warner Brothers shorts as well as other slapstick-style comedies.

The story itself follows a bumbling treasure hunter as he explores a set of newly discovered ancient ruins in the hopes of finding untold riches. His fumbling missteps wake the inhabitant of the ruins, who turns out to be a mischievous and clever monkey. This monkey does not take kindly to the treasure hunter’s theft of his possessions and so sets about the …

The Semi-Volatile Fraction Of Atmospheric Aerosols, Daniel J. Ruff

Theses

Atmospheric aerosols are significant contributor to climate effects as well as health problems. Many of these aerosols are mostly organic where their effects are dependent on their chemical composition. Atmospheric aerosols consist of a complex mixture of organic and inorganic components. The properties of the organic components within the aerosols can vary widely including the degree of oxidation and their vapor pressure. Recent studies have shown that a large fraction of newly formed atmospheric aerosols are semi-volatile and may vaporize back into the environment. This semi-volatile fraction of organic aerosols is largely unknown due to its difficulty to model. We …

Presentation And Outcomes After Medical And Surgical Treatment Versus Medical Treatment Alone Of Spontaneous Infectious Spondylodiscitis: A Systematic Literature Review And Meta-Analysis., Davis G Taylor, Avery L Buchholz, Durga R Sure, Thomas J Buell, James H Nguyen, Ching-Jen Chen, Joshua M Diamond, Perry A Washburn, James Harrop, Christopher I Shaffrey, Justin S Smith

Department of Medicine Faculty Papers

Study Design: Systematic literature review.

Objectives: The aims of this study were to (1) describe the clinical features, disabilities, and incidence of neurologic deficits of pyogenic spondylodiscitis prior to treatment and (2) compare the functional outcomes between patients who underwent medical treatment alone or in combination with surgery for pyogenic spondylodiscitis.

Methods: A systematic literature review was performed using PubMed according to PRISMA guidelines. No year restriction was put in place. Statistical analysis of pooled data, when documented in the original report (ie, number of patients with desired variable and number of patients evaluated), was conducted to determine the most …

Spinal Infections: From Prevention To Cure, James Harrop

Department of Neurosurgery Faculty Papers

AOSpine North America (AOSNA) is honored to have the ability to present this focused issue on spinal infections. As we are all aware, spinal infections are a prevalent part of our daily treatment regimen as spine surgeons—whether these infections are in our elective practice or emergencies.