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2018

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New Grant To Fund Video Game Designed To Help Kids With Adhd Learn Academic Skills (October 16, 2018), University Communications And Marketing Oct 2018

New Grant To Fund Video Game Designed To Help Kids With Adhd Learn Academic Skills (October 16, 2018), University Communications And Marketing

OHIO News Articles Archive

No abstract provided.


The Daily Gamecock, Monday, October 16, 2018, University Of South Carolina, Office Of Student Media Oct 2018

The Daily Gamecock, Monday, October 16, 2018, University Of South Carolina, Office Of Student Media

October

No abstract provided.


Protein Imbalance In The Development Of Skeletal Muscle Wasting In Tumour-Bearing Mice, Jacob L. Brown, David E. Lee, Megan E. Rosa-Caldwell, Lemuel A. Brown, Richard A. Perry, Wesley S. Haynie, Kendra Huseman, Kavithalakshmi Sataranatarajan, Holly Van Remmen, Tyrone A. Washington, Michael P. Wiggs, Nicholas P. Greene Oct 2018

Protein Imbalance In The Development Of Skeletal Muscle Wasting In Tumour-Bearing Mice, Jacob L. Brown, David E. Lee, Megan E. Rosa-Caldwell, Lemuel A. Brown, Richard A. Perry, Wesley S. Haynie, Kendra Huseman, Kavithalakshmi Sataranatarajan, Holly Van Remmen, Tyrone A. Washington, Michael P. Wiggs, Nicholas P. Greene

Health & Kinesiology Faculty Publications and Presentations

Background: Cancer cachexia occurs in approximately 80% of cancer patients and is a key contributor to cancer-related death. The mechanisms controlling development of tumour-induced muscle wasting are not fully elucidated. Specifically, the progression and development of cancer cachexia are underexplored. Therefore, we examined skeletal muscle protein turnover throughout the development of cancer cachexia in tumour-bearing mice. Methods: Lewis lung carcinoma (LLC) was injected into the hind flank of C57BL6/J mice at 8 weeks age with tumour allowed to develop for 1, 2, 3, or 4 weeks and compared with PBS injected control. Muscle size was measured by cross-sectional area analysis …


Visual And Verbal Serial List Learning In Patients With Statistically-Determined Mild Cognitive Impairment, Victor J. Wasserman Oct 2018

Visual And Verbal Serial List Learning In Patients With Statistically-Determined Mild Cognitive Impairment, Victor J. Wasserman

Theses and Dissertations

Objective: To compare verbal versus visual serial list learning test performance in mild cognitive impairment (MCI) and assess relationships between serial list learning and hippocampal volume. Methods: Patients were diagnosed with non-MCI, amnestic MCI (aMCI), and combined mixed/dysexecutive MCI (mixed/dysMCI). Outcome measures included immediate/delay free recall, and delay recognition performance from the 12-word Philadelphia Verbal Learning Test (PrVLT) and the Brief Visuospatial Memory Test-Revised (BVMT-R). Lateral hippocampal volumes were obtained. Results: Non-MCI patients scored better than other groups on P(r)VLT immediate/delay free recall. aMCI patients scored lower than other groups on P(r)VLT delay recognition. Non-MCI patients were …


An Evaluation Of Sciaenid Growth In The Gulf Of Mexico, Shane Flinn Oct 2018

An Evaluation Of Sciaenid Growth In The Gulf Of Mexico, Shane Flinn

LSU Master's Theses

Growth models estimate life history parameters that are used in the management of fisheries stocks. The most commonly used growth model in fisheries is the von Bertalanffy growth model (VBGM), yet it has been shown to provide a poor fit for length-at-age data of some species and other models exist. I reviewed 196 peer-reviewed age and growth studies and 50 NOAA stock assessments to examine temporal trends in the use of growth models and model selection in fisheries. I found that the use of multi-model frameworks has increased since the year 2000 and information theoretic approaches are replacing goodness-of-fit and …


October 16, 2018, The Dakota Student Oct 2018

October 16, 2018, The Dakota Student

The Dakota Student

No abstract provided.


Exposure Of A Population Of Invasive Wild Pigs To Simulated Toxic Bait Containing Biomarker: Implications For Population Reduction, Nathan P. Snow, Michael J. Lavelle, Joseph M. Halseth, Michael P. Glow, Eric H. Vannatta, Amy J. Davis, Kim M. Pepin, Rustin T. Tabor, Bruce R. Leland, Linton D. Staples, Kurt C. Vercauteren Oct 2018

Exposure Of A Population Of Invasive Wild Pigs To Simulated Toxic Bait Containing Biomarker: Implications For Population Reduction, Nathan P. Snow, Michael J. Lavelle, Joseph M. Halseth, Michael P. Glow, Eric H. Vannatta, Amy J. Davis, Kim M. Pepin, Rustin T. Tabor, Bruce R. Leland, Linton D. Staples, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

BACKGROUND: An international effort to develop an acute and humane toxic bait for invasive wild pigs (Sus scrofa) is underway to curtail their expansion. We evaluated the ability to expose a population of wild pigs to a simulated toxic bait (i.e., placebo bait containing a biomarker, rhodamine B, in lieu of the toxic ingredient) to gain insight on potential population reduction. We used 28 GPS-collars and sampled 428 wild pigs to examine their vibrissae for evidence of consuming the bait.

RESULTS: We estimated that 91% of wild pigs within 0.75 km of bait sites (total area = 16.8 …


Terminal Pleistocene–Holocene Avifauna Of San Miguel And Santa Rosa Islands: Identifications Of Previously Unidentified Avian Remains Recovered From Fossil Sites And Prehistoric Cave Deposits, Paul W. Collins, Daniel A. Guthrie, Emily L. Whistler, Rene L. Vellanoweth, Jon M. Erlandson Oct 2018

Terminal Pleistocene–Holocene Avifauna Of San Miguel And Santa Rosa Islands: Identifications Of Previously Unidentified Avian Remains Recovered From Fossil Sites And Prehistoric Cave Deposits, Paul W. Collins, Daniel A. Guthrie, Emily L. Whistler, Rene L. Vellanoweth, Jon M. Erlandson

Western North American Naturalist

We provide an update to the fossil avifauna of San Miguel and Santa Rosa Islands based on the identification of 3509 small bird bones recovered from fossil sites on Santa Rosa and from 3 archaeological-paleontological cave deposits and 20 fossil sites on San Miguel. This work adds 64 species to the fossil avian community of these 2 islands, increasing the previous total from 83 to 147 species, making this the richest Late Pleistocene–Holocene coastal avifaunal assemblage recorded for California. Of the 64 newly identified species, 62 are new additions to the Channel Islands fossil avifauna and 40 are new to …


The Prospector, October 16, 2018, Utep Student Publications Oct 2018

The Prospector, October 16, 2018, Utep Student Publications

The Prospector

Headline: Rain or Shine Chalk the Block Continues On


Resveratrol Sustains Insulin-Degrading Enzyme Activity Toward Aβ42, Claire A. Krasinski, Valerie A. Ivancic, Qiuchen Zheng, Donald E. Spratt, Noel D. Lazo Oct 2018

Resveratrol Sustains Insulin-Degrading Enzyme Activity Toward Aβ42, Claire A. Krasinski, Valerie A. Ivancic, Qiuchen Zheng, Donald E. Spratt, Noel D. Lazo

Chemistry

Alzheimer's disease (AD), the most common cause of dementia in the elderly, is the sixth leading cause of death in the United States. We hypothesize that the impaired clearance of Aβ42 from the brain is partly responsible for the onset of sporadic AD. In this work, we evaluated the activity of insulin-degrading enzyme (IDE) toward Aβ42 in the presence of resveratrol, a polyphenol found in red wine and grape juice. By liquid chromatography/mass spectrometry, we identified initial cleavage sites in the absence and presence of resveratrol that carry biological relevance connected to the amyloidogenic properties of Aβ42. Incubation with resveratrol …


A Comparison Of Algorithms For Finding An Efficient Theme Park Tour, Liz Bouzarth, Richard J. Forrester, Kevin Hutson, Rahul Isaac, James Midkiff, Danny Rivers, Leonard J. Testa Oct 2018

A Comparison Of Algorithms For Finding An Efficient Theme Park Tour, Liz Bouzarth, Richard J. Forrester, Kevin Hutson, Rahul Isaac, James Midkiff, Danny Rivers, Leonard J. Testa

Mathematics Publications

The problem of efficiently touring a theme park so as to minimize the amount of time spent in queues is an instance of the Traveling Salesman Problem with Time-Dependent Service Times (TSP-TS). In this paper, we present a mixed-integer linear programming formulation of the TSP-TS and describe a branch-and-cut algorithm based on this model. In addition, we develop a lower bound for the TSP-TS and describe two metaheuristic approaches for obtaining good quality solutions: a genetic algorithm and a tabu search algorithm. Using test instances motivated by actual theme park data, we conduct a computational study to compare the effectiveness …


Papaverine And Its Derivatives Radiosensitize Solid Tumors By Inhibiting Mitochondrial Metabolism, Martin Benej, Xiangqian Hong, Sandip Vibhute, Sabina Scott, Jinghai Wu, Edward Graves, Quynh-Thu Le, Albert C. Koong, Amato J. Giaccia, Bing Yu, Ching-Shih Chen, Ioanna Papandreou, Nicholas C. Denko Oct 2018

Papaverine And Its Derivatives Radiosensitize Solid Tumors By Inhibiting Mitochondrial Metabolism, Martin Benej, Xiangqian Hong, Sandip Vibhute, Sabina Scott, Jinghai Wu, Edward Graves, Quynh-Thu Le, Albert C. Koong, Amato J. Giaccia, Bing Yu, Ching-Shih Chen, Ioanna Papandreou, Nicholas C. Denko

Biomedical Engineering Faculty Research and Publications

Tumor hypoxia reduces the effectiveness of radiation therapy by limiting the biologically effective dose. An acute increase in tumor oxygenation before radiation treatment should therefore significantly improve the tumor cell kill after radiation. Efforts to increase oxygen delivery to the tumor have not shown positive clinical results. Here we show that targeting mitochondrial respiration results in a significant reduction of the tumor cells’ demand for oxygen, leading to increased tumor oxygenation and radiation response. We identified an activity of the FDA-approved drug papaverine as an inhibitor of mitochondrial complex I. We also provide genetic evidence that papaverine’s complex I inhibition …


Crash/Near-Crash: Impact Of Secondary Tasks And Real-Time Detection Of Distracted Driving, Peter Ramzy Zaki Bakhit Oct 2018

Crash/Near-Crash: Impact Of Secondary Tasks And Real-Time Detection Of Distracted Driving, Peter Ramzy Zaki Bakhit

LSU Doctoral Dissertations

The main goal of this dissertation is to investigate the problem of distracted driving from two different perspectives. First, the identification of possible sources of distraction and their associated crash/near-crash risk. That can assist government officials toward more informed decision-making process, allowing for optimized allocation of available resources to reduce roadway crashes and improve traffic safety. Second, actively counteracting the distracted driving phenomenon by quantitative evaluation of eye glance patterns.

This dissertation research consists of two different parts. The first part provides an in-depth analysis for the increased crash/near-crash risk associated with different secondary task activities using the largest real-world …


An Attainable Global Vision For Conservation And Human Well-Being, Heather M. Tallis, Peter L. Hawthorne, Stephen Polasky, Joseph Reid, Michael W. Beck, Kate Brauman, Jeffrey M. Bielicki, Seth Binder, Matthew G. Burgess, Emily Cassidy, Adam Clark, Joseph Fargione, Edward T. Game, James Gerber, Forest Isbell, Joseph Kiesecker, Robert Mcdonald, Marc Metian, Jennifer L. Molnar, Nathan D. Mueller, Christine S. O'Connell, Daniel Ovando, Max Troell, Timothy M. Boucher, Brian Mcpeek Oct 2018

An Attainable Global Vision For Conservation And Human Well-Being, Heather M. Tallis, Peter L. Hawthorne, Stephen Polasky, Joseph Reid, Michael W. Beck, Kate Brauman, Jeffrey M. Bielicki, Seth Binder, Matthew G. Burgess, Emily Cassidy, Adam Clark, Joseph Fargione, Edward T. Game, James Gerber, Forest Isbell, Joseph Kiesecker, Robert Mcdonald, Marc Metian, Jennifer L. Molnar, Nathan D. Mueller, Christine S. O'Connell, Daniel Ovando, Max Troell, Timothy M. Boucher, Brian Mcpeek

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

A hopeful vision of the future is a world in which both people and nature thrive, but there is little evidence to support the feasibility of such a vision. We used a global, spatially explicit, systems modeling approach to explore the possibility of meeting the demands of increased populations and economic growth in 2050 while simultaneously advancing multiple conservation goals. Our results demonstrate that if, instead of “business as usual” practices, the world changes how and where food and energy are produced, this could help to meet projected increases in food (54%) and energy (56%) demand while achieving habitat protection …


A Simple, Sensitive And Reliable Lc-Ms/Ms Method For The Determination Of 7-Bromo-5-Chloroquinolin-8-Ol (Clbq14), A Potent And Selective Inhibitor Of Methionine Aminopeptidases: Application To Pharmacokinetic Studies, Oscar Ekpenyong, Candace Cooper, Jing Ma, Dong Liang, Omonike Olaleye, Huan Xie Oct 2018

A Simple, Sensitive And Reliable Lc-Ms/Ms Method For The Determination Of 7-Bromo-5-Chloroquinolin-8-Ol (Clbq14), A Potent And Selective Inhibitor Of Methionine Aminopeptidases: Application To Pharmacokinetic Studies, Oscar Ekpenyong, Candace Cooper, Jing Ma, Dong Liang, Omonike Olaleye, Huan Xie

Faculty Publications

CLBQ14 is an 8-hydroxyquinoline analogue that inhibits methionine aminopeptidase (MetAP), an enzyme responsible for the post-translational modification of several proteins and polypeptides. MetAP has been validated as druggable target for some infectious diseases, and its inhibitors have been investigated as potential therapeutic agents. In this study, we developed and validated a liquid chromatography tandem-mass spectrometry (LC-MS/MS) method for the quantification of CLBQ14 in solution, and in rat plasma and urine. This method was applied to the pharmacokinetic evaluation of CLBQ14 in adult male Sprague Dawley (SD) rats. Chromatographic separation was achieved using an ultra-high-performance liquid chromatography (UHPLC) system equipped with …


Percina Ouachitae - Saddleback Darter, Roger W. Barbour Oct 2018

Percina Ouachitae - Saddleback Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

Percina ouachitae - Saddleback Darter


Percina Palmaris - Bronze Darter, Roger W. Barbour Oct 2018

Percina Palmaris - Bronze Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

Percina palmaris - Bronze Darter


Percina Pantherina - Leopard Darter, Roger W. Barbour Oct 2018

Percina Pantherina - Leopard Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

Percina pantherina - Leopard Darter


Percina Palmaris - Bronze Darter, Roger W. Barbour Oct 2018

Percina Palmaris - Bronze Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

Percina palmaris - Bronze Darter


Percina Phoxocephala - Slenderhead Darter, Roger W. Barbour Oct 2018

Percina Phoxocephala - Slenderhead Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

Percina phoxocephala - Slenderhead Darter


Percina Roanoaka - Roanoke Darter, Roger W. Barbour Oct 2018

Percina Roanoaka - Roanoke Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

Percina roanoaka - Roanoke Darter


Percina Sciera Apristis - Dusky Darter, Roger W. Barbour Oct 2018

Percina Sciera Apristis - Dusky Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

Percina sciera apristis - Dusky Darter


Phenacobius Uranops - Stargazing Minnow, Roger W. Barbour Oct 2018

Phenacobius Uranops - Stargazing Minnow, Roger W. Barbour

Roger W. Barbour Slide Collection

Phenacobius uranops - Stargazing Minnow


Percina Uranidea - Stargazing Darter, Roger W. Barbour Oct 2018

Percina Uranidea - Stargazing Darter, Roger W. Barbour

Roger W. Barbour Slide Collection

Percina uranidea - Stargazing Darter


Phenacobius Crassilabrum - Fatlips Minnow, Roger W. Barbour Oct 2018

Phenacobius Crassilabrum - Fatlips Minnow, Roger W. Barbour

Roger W. Barbour Slide Collection

Phenacobius crassilabrum - Fatlips Minnow


Phoxinus Oreas - Mountain Redbelly Dace, Roger W. Barbour Oct 2018

Phoxinus Oreas - Mountain Redbelly Dace, Roger W. Barbour

Roger W. Barbour Slide Collection

Phoxinus oreas - Mountain Redbelly Dace


Phoxinus Cumberlandensis - Blackside Dace, Roger W. Barbour Oct 2018

Phoxinus Cumberlandensis - Blackside Dace, Roger W. Barbour

Roger W. Barbour Slide Collection

Phoxinus cumberlandensis - Blackside Dace


Pimephales Promelas - Fathead Minnow, Roger W. Barbour Oct 2018

Pimephales Promelas - Fathead Minnow, Roger W. Barbour

Roger W. Barbour Slide Collection

Pimephales promelas - Fathead Minnow


Poecilia Latipinna - Sailfin Molly, Roger W. Barbour Oct 2018

Poecilia Latipinna - Sailfin Molly, Roger W. Barbour

Roger W. Barbour Slide Collection

Poecilia latipinna - Sailfin Molly


Pomoxis Nigromaculatus - Black Crappie, Roger W. Barbour Oct 2018

Pomoxis Nigromaculatus - Black Crappie, Roger W. Barbour

Roger W. Barbour Slide Collection

Pomoxis nigromaculatus - Black Crappie