Digital Commons Network^™

The Mechanisms Shaping The Repertoire Of Cd4(+)Foxp3(+) Regulatory T Cells, Piotr Kraj, Leszek Ignatowicz

Biological Sciences Faculty Publications

Regulatory T (Treg) cells expressing Foxp3 transcription factor control homeostasis of the immune system, antigenic responses to commensal and pathogenic microbiota, and immune responses to self and tumour antigens. The Treg cells differentiate in the thymus, along with conventional CD4⁺ T cells, in processes of positive and negative selection. Another class of Treg cells is generated in peripheral tissues by inducing Foxp3 expression in conventional CD4⁺ T cells in response to antigenic stimulation. Both thymic and peripheral generation of Treg cells depends on recognition of peptide/MHC ligands by the T-cell receptors (TCR) expressed on thymic Treg precursors or …

Characterizing Habitat Suitability For A Central‐Place Forager In A Dynamic Marine Environment, Dana K. Briscoe, Sabrina Fossette, Kylie L. Scales, Elliott L. Hazen, Steven J. Bograd, Sara M. Maxwell, Elizabeth A. Mchuon, Patrick W. Robibson, Carey Kuhn, Daniel P. Costa, Larry B. Crowder, Rebecca L. Lewison

Biological Sciences Faculty Publications

Characterizing habitat suitability for a marine predator requires an understanding of the environmental heterogeneity and variability over the range in which a population moves during a particular life cycle. Female California sea lions (Zalophus californianus) are central‐place foragers and are particularly constrained while provisioning their young. During this time, habitat selection is a function of prey availability and proximity to the rookery, which has important implications for reproductive and population success. We explore how lactating females may select habitat and respond to environmental variability over broad spatial and temporal scales within the California Current System. We combine near‐real‐time …

Quotidian Intimidation And Mussolini's Special Tribunal In Istria And The Eastern Borderlands, Maura Hametz

History Faculty Publications

The article examines the Special Tribunal for the Defense of the State's use of the "no grounds to proceed" ruling to intimidate anti-fascists and extend the fascist government's power in the Adriatic borderlands. It demonstrates how the Tribunal's judges used their sentencing prerogatives to support repression in Istria and cloak persecution in the mantel of legal action in defense of the state.

Motivations, Specializations, Identities, And Constraints Associated With Hunting In Nebraska, Alisha Grams

School of Natural Resources: Dissertations, Theses, and Student Research

No abstract provided.

Plastid Dna Variation Of The Endemic Species Oxytropis Glandulosa Turcz. (Fabaceae), Alla Kholina, Marina Kozyrenko, Elena Artyukova, Denis Sandanov, Inessa Selyutina, Daba Chimitov

Turkish Journal of Botany

Oxytropis glandulosa Turcz. (Fabaceae) is a rare perennial plant endemic to Buryatia (Russia). We sequenced three intergenic spacers (the psbA−trnH, trnL−trnF, and trnS−trnG) of chloroplast DNA (cpDNA) in specimens of four populations from two geographic regions (Barguzin and Yeravna depressions) within this species range. The levels of haplotype and nucleotide diversity varied in the range of 0.133−0.911 and 0.0002−0.0059, respectively. The highest values of these parameters are characteristic of populations located in the Barguzin depression. Variable sites detected within the intergenic spacers allowed the identification of eleven haplotypes; nine of them were found in the populations from the Barguzin depression …

Predicting The Potential Distribution Area Of Solidago Xniederederi (Asteraceae), Malgorzata Jazwa, Elzbieta Jedrzejczak, Ewelina Klichowska, Artur Pliszko

Turkish Journal of Botany

In this study, we aimed to investigate the potential distribution area of Solidago xniederederi, a natural hybrid between North American S. canadensis and European S. virgaurea, in Central and East Europe using the MAXENT modeling approach. The final MAXENT model was constructed based on 83 occurrence records from Austria, Poland, Lithuania, and Latvia and six abiotic environmental variables. The jackknife test revealed that annual temperature range, mean temperature of wettest quarter, and minimum temperature of coldest month had the highest gain for the training and test data when used alone, whereas precipitation seasonality, precipitation of coldest quarter, and precipitation of …

New Additions To The Turkish Pezizales, Yasi̇n Uzun, Semi̇ha Yakar, İbrahi̇m Hali̇l Karacan, Abdullah Kaya

Turkish Journal of Botany

Twelve members of the order Pezizales are recorded for the first time from Turkey: Ascobolus carbonarius P.Karst.; A. crenulatus P.Karst.; A. foliicola Berk. & Broome; A. immersus Pers.; Saccobolus glaber (Pers.) Lambotte; Thecotheus holmskioldii (E.C.Hansen) Eckblad (Ascobolaceae Boud. ex Sacc.); Lasiobolus cuniculi Velen. (Ascodesmidaceae J.Schröt.); Barssia hellenica Kaounas, Agnello, P.Alvarado & Slavova (Helvellaceae Fr.); Marcelleina atroviolacea Brumm.; M. rickii (Rehm) Graddon (Pezizaceae Dumort.); Cheilymenia pulcherrima (P.Crouan & H.Crouan) Boud.; and Sepultariella semi-immersa (P.Karst.) Van Vooren, U.Lindem. & Healy (Pyronemataceae Corda). Three of them, S. glaber (Pers.) Lambotte; B. hellenica Kaounas, Agnello, P.Alvarado & Slavova; and S. semi-immersa (P.Karst.) Svrcek, are …

Players In A Storm: Climate And Political Migrants In The Tempest And Othello, Darcie Rees

Master's Theses and Doctoral Dissertations

This paper presents a reading of migrants and their relationships with political and environmental slow violence in William Shakespeare’s The Tempest and Othello. Using Steve Mentz’s work with water and shipwreck, Lowell Duckert’s work on water in Shakespeare, Rob Nixon’s concept “slow violence,” Patricia Fumerton’s book on vagrancy in sixteenth and seventeenth century England, and Ken Hiltner’s work with environmental advocacy of the same time, I read the social history of vagrancy of the time (presented by Hiltner and Fumerton) alongside the Poor Laws. This social history is combined with water-focused ecocriticism, shipwreck and a postcolonial reading of migrancy. Ultimately, …

The Costume Design Of Little Women The Musical, Emily Kimball

All Graduate Theses, Dissertations, and Other Capstone Projects

This document is a thesis submitted in partial fulfillment for the Master of Fine Arts degree in theatre. It is an account of the author Emily Kimball's artistic process in creating and executing the design for Minnesota State University, Mankato's production of Little Women the Musical in the fall of 2017. The thesis chronicles the designer's process from early production through construction and performance in a total of five chapters: an early production analysis, a historical and critical perspective, a journal, a post-production analysis and a process development analysis. Appendices and works cited are included.

2018 Faculty Accomplishments Reception, University Of Richmond

Faculty Accomplishments Reception Programs

Program for the 2018 Faculty Accomplishments Reception

In Honor of University of Richmond Faculty Contributions to Scholarship, Research and Creative Work, January 2017 - December 2017

March 30, 2018, 3:00 - 4:30 p.m.
Boatwright Memorial Library, Research & Collaborative Study Area, First Floor

Irrational Science Breeds Irrational Law, Caleb Small

Emory Law Journal

Current jurisprudence regarding the subject matter eligibility requirement for patents relies upon outdated assumptions in both philosophy of science and the scientific endeavor itself. In relying upon these assumptions, the Supreme Court, especially in its recent decisions covering biotechnology and computer software, has given the arguably more technocratic lower federal court judges a confusing and unworkable test. Scholars have proposed new approaches on subject matter eligibility, urging courts to revisit and revitalize other areas of the patentability analysis: utility and the written description requirement. While these arguments adeptly characterize some solutions to the current predicament, they do so without utilizing …

Enforcing An Unenforceable Law: The National Bioengineered Food Disclosure Standard, Mary Christine Brady

Emory Law Journal

Congress hastily crafted the National Bioengineered Food Disclosure Standard (¿GE labeling law¿ or Act), which it passed in July of 2016, to preempt various state laws that were cropping up around the country seeking to label genetically engineered ingredients (GEs). This Comment anticipates that the Act will face free speech challenges that may find the GE labeling law unconstitutional, especially following recent trends in First Amendment jurisprudence that have been increasingly applying stricter scrutiny upon constitutional review. Due to inconsistent applications of the two governing tests that review compelled commercial speech¿the Central Hudson and Zauderer standards, respectively¿this Comment suggests that …

Persona¿Character Copyrights And Merger¿S Role In The Evolution Of Entertainment Expressions, Sydney Altman

Emory Law Journal

This Comment defines what qualifies as a character and what makes the character eligible or ineligible for copyright protection. This Comment proposes placing characters on a spectrum, from those that are granted full copyright protection to those that are denied legal security. When the line is not clear regarding whether a character is an original expression or is a persona of the actor, this Comment suggests utilizing the merger doctrine as a personal affirmative defense to eliminate a studio¿s inflexible copyright control and to release the character into the actor¿s shared control.

Bioethics & Vulnerability: Recasting The Objects Of Ethical Concern, Michael Thomson

Emory Law Journal

Mainstream bioethics has long been challenged for its focus on the technological developments of biomedicine and principles of individual ethics. It is argued that the focus on these particular objects, and the delisting of the social context within which the ethical is constructed and experienced, limits the extent to which bioethics provides a contesting counter-weight to modern biomedicine. In response, this Article promotes Martha Fineman¿s vulnerability theory as a new framework for bioethical deliberation. Fineman¿s foundational concern with the embodied and embedded experience of being human puts the social at the heart of analytical enquiry. Further, a focus on the …

Disturbance Of Redox Homeostasis In Down Syndrome: Role Of Iron Dysmetabolism, Eugenio Barone, Andrea Arena, Elizabeth Head, D. Allan Butterfield, Marzia Perluigi

Sanders-Brown Center on Aging Faculty Publications

Down syndrome (DS) is the most common genetic form of intellectual disability that leads in the majority of cases to development of early-onset Alzheimer-like dementia (AD). The neuropathology of DS has several common features with AD including alteration of redox homeostasis, mitochondrial deficits, and inflammation among others. Interestingly, some of the genes encoded by chromosome 21 are responsible of increased oxidative stress (OS) conditions that are further exacerbated by decreased antioxidant defense. Previous studies from our groups showed that accumulation of oxidative damage is an early event in DS neurodegeneration and that oxidative modifications of selected proteins affects the integrity …

Expatriation Restored, Jonathan David Shaub

Law Faculty Scholarly Articles

Expatriation - the loss or relinquishment of citizenship - has a long and divisive history as a fundamental concept of American citizenship. It has been the subject of contentious and robust debate from the very beginning of the country. This Article posits that the concept of expatriation today has little jurisprudential salience, despite its increasing rhetorical valence in the context of terrorism, because the historical development of the concept has obscured its meaning. Expatriation originally had a precise meaning: an individual right declared by the country in 1868 to be "indispensable" to the inalienable rights identified in the Declaration of …

Registration Is Fundamental, Brian L. Frye, Nicole E. Pottinger

Law Faculty Scholarly Articles

Under the Copyright Act, copyright owners can file infringement actions only if registration of their copyright claim with the Copyright Office “has been made” or “has been refused.” The United States Supreme Court recently granted certiorari in Fourth Estate v. Wall-Street.com, in order to decide whether registration is “made” when a claimant files a registration application or when the Copyright Office registers the claim.

This article argues that the Court should hold that registration occurs when the Copyright Office registers the claim, in order to ensure that federal courts can benefit from the expertise of the Copyright Office. The Copyright …

The Lion, The Bat & The Thermostat: Metaphors On Consciousness, Brian L. Frye

Law Faculty Scholarly Articles

No abstract provided.

Undergraduate Catalog, 2018-2019, University Of South Florida St. Petersburg.

Undergraduate Catalogs

No abstract provided.

Conversation, Cooperation, Or Convention? A Response To Kar And Radin, Jeffrey M. Lipshaw

Suffolk University Law School Faculty Works

This is a response to Pseudo-Contract and Shared Meaning Analysis by Professors Robin Bradley Kar and Margaret Radin. Their article is a thoughtful and ambitious attempt to find a principled basis in the theory of contract formation for distinguishing what they see as the legitimate portion of the transaction – the “actual agreement” which is “cooperatively communicated” – from that which ought not to be enforced (usually the extensive unread boilerplate or click-through terms). While I am sympathetic to the policy aim, I resist the core of their thesis, which is that there is a discernible “actual agreement” arising from …

Algae Biofuel Triacylglyceride Transesterification Optimization, Erik Ferenczy

Senior Honors Theses

Algae biofuels may hold the key to solving the problem of fossil fuel consumption by being comparable in content, renewable, and carbon-neutral. Many biofuel researchers and corporations have undertaken to increase the production rate or capacity of triacylglycerides (TAG), the fat precursor to biodiesel fuel produced by algae, in algae cultures and published articles documenting their findings. This research is devoted to evaluating the effect of water that may be present in samples on the conversion efficiency of TAG into fatty acid methyl esters (FAME), commonly referred to as biodiesel. Therefore, that efficiency was studied to find the water content …

Effects Of Crisis News On Intercultural Tolerance: An International Comparative Study, Anthony Eseke

International Crisis and Risk Communication Conference

Human beings are “cultural animals who know and see and hear the world through socially constructed filters.” [1]. Fundamental to these filters are identities. Through the frames of identity, people often negotiate the dialectics of the ‘self’ with/against ‘the other’. The media in their reportage of conflicts and crisis produce and reinforce these dialectics. However, to what extent and directions do these reports influence social tolerance in the audience? This study therefore examined the effects of crisis/conflict news on otherness. The study defined otherness as the appraisal attitudes of tolerance, apathy, or intolerance towards other bodies based on identity categories. …

Impact Of Increased Green Turtle Nesting On Loggerhead Fitness, Amanda R. Carmichael

Honors Undergraduate Theses

Marine turtles exhibit strong fidelity to their nesting beaches, making the conservation of nesting beaches important for ensuring successful sea turtle populations. Conservation of these nesting beaches involves understanding how species interact with the environment and each other, and understanding how environmental change and population growth can affect the suitability of the nesting habitat. The Archie Carr National Wildlife Refuge (ACNWR) is unusual in its high density of sea turtle nesting by two species: green (Chelonia mydas) and loggerhead (Caretta caretta) turtles. The ACNWR in Melbourne Beach, Florida was established in 1991 due to the high density of loggerhead nesting, …

Reconstructing The Vocal Capabilities Of Homo Heidelbergensis, A Close Human Ancestor, Austin Blake Stanley

Honors Undergraduate Theses

The discovery of 5,500 Homo heidelbergensis fossil specimens at the Sima de los Huesos archaeological site in Spain has opened up the opportunity for research to be conducted on the vocal capabilities of this species. Previous research has revealed that the range of vowel sounds an individual can produce, known as the vowel space, is directly affected by the dimensions of the vocal tract. The vowel spaces of two hominins, Homo sapiens and Homo neanderthalensis, have been reconstructed through previous research. However, the vowel space of Homo heidelbergensis has not yet been reconstructed. In this research, I aim to …

The Relationship Between Millennials' Attitudes Towards The United States And Their Goals And Personal Constructs, Angelica M. Hernandez

Honors Undergraduate Theses

The purpose of this study was to examine various aspects of Millennials' attitudes related to their beliefs about the United States and in the context of their personal, career, and family goals and ethnic identity. Another purpose of this study was to determine if selected personality variables would predict attitudes toward the United States. It was found that Millennials who held positive attitudes toward the United States in terms of being a viable country for them also had relatively clear and developed personal, career, and family goals. Moreover, three personality variables—resiliency, optimism, and (inversely) cynicism significantly contributed to Millennials' views …

Oyster Reef Restoration: Impacts On Infaunal Communities In A Shallow Water Estuary, Katherine P. Harris

Honors Undergraduate Theses

Oyster reefs are important estuarine ecosystems that provide habitat to many species including threatened and endangered wading birds and commercially important fishes and crabs. Infaunal organisms (i.e. small, aquatic animals that burrow in the sediment) are also supported by oyster reef habitats. Infaunal organisms are critical to marine food webs and are consumed by many important species that inhabit coastal estuaries. However, over the past century 85% of shellfish reef habitats have been lost, making restoration of these areas vital. Due to their important role in coastal food webs, infauna is hypothesized to be a strong indicator of habitat productivity …

Investigating The Role Of The Caspase-6 Cleavage Fragment Of Mutant Huntingtin In Huntington Disease Pathogenesis, Jourdan A. Mckinnis

Honors Undergraduate Theses

Huntington disease (HD) is a devastating and fatal neurodegenerative disease. At the moment, no disease modifying therapies are available, with only symptomatic treatment offered to alleviate psychiatric and some types of motor deficits. As a result, many people will continue to suffer and die from this disease. Small molecule therapies have failed to provide benefit in HD, necessitating more complex gene therapy approaches and the identification of less traditional therapeutic targets. A previous study demonstrated that preventing cleavage of the huntingtin (HTT) protein, the protein that when mutated causes HD, by caspase 6 (C6) at amino acid 586 prevents the …

Can Nox1 Activity Initiate Parkinson's-Like Pathology In An Enteroendocrine Cell Line?, Evan Adler

Honors Undergraduate Theses

Increased attention has been given to the gut lately in a number of conditions, from maintaining health via the use of probiotics to treating Autism Spectrum Disorder. Parkinson's Disease has a history with the gut starting with the Braak hypothesis, in which eminent researcher Heiko Braak observed that the spread of Parkinson's (PD) seemed to occur along either olfactory or enteric neurons prior to reaching the substantia nigra in the midbrain, where the classical disease symptoms become evident. Though this finding was largely ignored at the time, the possibility of a gut origin for PD has received interest lately as …

Understanding News Media Viewing And Selection Patterns: Fomo And User Consumption Of News Content On Social Media Interfaces, Nicolette D. Christopher

Honors Undergraduate Theses

The current study employs a regional sample in order to investigate the phenomenon of fear-of-missing-out (FoMO), the awareness associated with the fear that other individuals are having a more pleasurable experience that one is not a part of. The current study uniquely examines the role that FoMO plays in viewing patterns associated with news content on social media interfaces. The 10-item scale created by Przybylski, Myrayama, DeHaan, and Gladwell in 2013 was used as a basis to discover the degree of FoMO participants experience while online, while other questions of the survey serve to collect data about participants sociodemographic's, engagement …

Investigating The Role Of The Gut Microbiome In Huntington Disease, Casey G. Hart

Honors Undergraduate Theses

Huntington disease (HD) is an inherited neurodegenerative disease caused by a trinucleotide repeat expansion in the huntingtin (HTT) gene. Metabolic dysfunction is a feature of HD that is recapitulated in HD mouse models. Our lab has shown that circadian feeding rhythms are disrupted in humanized HD mice and restored by suppression of brain HTT. Furthermore, when circadian feeding rhythm is artificially restored, in addition to normalization of metabolic function, liver and striatal HTT is temporarily reduced, demonstrating that HTT is involved in gut-brain feedback. The gut microbiome, which can regulate gut-brain feedback, has been implicated in the pathogenesis …