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Cold Exposure Effects On Cardiac Function And Synaptic Transmission At The Neuromuscular Junction In Invertebrates, Yuechen Zhu, Robin L. Cooper

Biology Faculty Publications

This review emphasizes how ectothermic animals respond physiologically to environmental temperature changes and cold stress. Generally ectothermic animals cannot generate heat to maintain their body temperature but they can still survive in various temperature zones. Various organisms have been analyzed anatomically and physiologically in the attempt to understand the underlying mechanisms of this temperature adaptation. A few of the changes in the metabolic and molecular function of proteins are discussed. The potential of how hormonal modulation of cardiac and nervous systems which influences responses during exposure cold exposure is also addressed. The focus of this review is on the effect …

Investigating The Effects Of Homocysteine As An Agonist On Invertebrate Glutamatergic Synapses, Elizabeth Grau, Alexandra E. Stanback, Alec Bradley, Danielle Cantrell, Samantha Eversole, Carolyn Grachen, Kaylee Hall, Danielle Hawthorne, Claire Kinmon, Paula Ortiz Guerrero, Bhavik Patel, Kaitlyn Samuels, Chinni Suryadevara, Gia Valdes, Samuel Wycoff, Robin L. Cooper

Biology Faculty Publications

Hyperhomocysteinemia (HHcy) in mammals can produce neurological deficits, such as memory loss. The cause of the neurological issues is assumed to be due to homocysteine (HCY) binding to glutamatergic receptors in the central nervous system (CNS). High levels of HCY in the CNS are also associated with Amyotrophic Lateral Sclerosis (ALS) and Parkinson’s disease. Thus, understanding the detailed mechanisms of HCY in model preparations could be useful in developing potential treatments to neurodegenerative diseases with overlapping symptoms to HHcy. The aim of this study is to investigate the efficacy of HCY as an agonist at glutamatergic synapses in invertebrates. The …

Female Agency In Fantasy Films Of The 1980s., Tara C. Rowland

Liberal Studies (MA) Final Essays

"Female Agency in Fantasy Films of the 1980s"

This study looks at female character roles in six of the major fantasy films produced during the 1980s. This research draws mostly on primary resources, the films, but includes commentary from research in the same vein. The purpose of this study was to show how certain fantasy films gave more agency and power to female characters in a genre often plagued with women who needed saving. Upon examination of these films, it becomes clear that not only is representation is an important part of film, especially for young children, but that it …

Who Gets What, When, How? Power, Organization, Markets, Money And The Allocation Of Resources, Martin Shubik

Cowles Foundation Discussion Papers

Money is a mystery and financial institutions are often regarded as guardians and promoters of the mystery. These sketches are designed to help an individual interested in, but not technically trained in economics, understand markets, money, credit and the evolution of a mass market system embedded in the rich context of its political environment and society. The efficient functioning of a dynamic economy requires the presence of money and financial institutions. The great variety of financial institutions in any advanced economy requires that a synthetic approach is used to understand what the whole looks like. Verbal description provides an overarching …

Death, Mourning, And Accommodation In The Missions Of Alta California.In Franciscans And American Indians In Pan-Borderlands Perspective: Adaptation, Negotiation,And Resistance, Lee M. Panich

Faculty Publications

Spanish missions are seen by many indigenous people and scholars alike as sites of profound loss. Across the Borderlands of North America, the native individuals and families who entered mission establishments faced terrible and often lethal challenges posed by introduced diseases, strict labor demands, corporal punishment, and unsanitary conditions. In California, as elsewhere, death was part and parcel of the mission experience for many indigenous neophytes as well as the resident Franciscan missionaries. This chapter explores how native people and Franciscans in Alta California negotiated their divergent but deeply held views about what constituted proper death, burial, and mourning practices. …

Predictors Of Pm 2.5 And Radon Concentrations In Residences Of Central Kentucky: A Cross Sectional Study, Kyle T. Hancock

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Aim: To measure levels of respirable particles (PM 2.5) and radon in homes in Central Kentucky and assess modifiable risk factors that could reduce the morbidity and mortality of cardiovascular and respiratory disease.

Methods: PM 2.5 and radon samples were taken in homes (n=21) in Central Kentucky. An in- home checklist was completed for each home that assessed a variety of potential environmental respiratory exposures.

Results: The geometric mean of PM 2.5 for all 21 homes was 8.4 μg/m³ which was well below the EPA air quality standard of 35 μg/m³. Smoking status, burning candles, and general …

Economic Growth And Changes In Forested Areas In Southeast Asia: Is Environmental Kuznets Curve Still Relevant?, Lan Thi Ngoc Nguyen

Undergraduate Honors Theses

The environmental history of the twentieth century in Southeast Asia reveals tremendous loss of forested areas as a consequence of unprecedented economic transformations and unrestrained globalization. Featuring some of the world’s fastest-growing economies, Southeast Asia has been experiencing fundamental changes in its economic structure, sociopolitical institutions, and the rate of natural resources extraction and depletion, including deforestation. This study reexamines evidence of the (EKC) hypothesis in light of the deforestation the above region experienced over the period 1990-2013. We use the change in forest cover as an indicator for environmental degradation. A panel co-integration approach is invoked to investigate the …

A Web-Based Interactive Tool To Reduce Childhood Obesity Risk In Urban Minority Youth: Usability Testing Study, Sandra Verdaguer, Katrina F. Mateo, Katarzyna Wyka, Tracy A. Dennis, May May Leung

Publications and Research

Background: Childhood obesity is a serious public health issue among minority youth in the United States. Technology-enhanced approaches can be effective for promoting healthy behavior change.

Objective: The purpose of this study was to test the usability of prototypes of a Web-based interactive tool promoting healthy dietary behaviors to reduce childhood obesity risk in urban minority youth. The Web-based tool comprised a manga-style comic with interactive features (eg, sound effects, clickable pop-ups), tailored messaging, and goal setting, and was optimized for use on tablet devices.

Methods: Latino and black/African American children ages 9 to 13 years were recruited to participate …

Single Olfactory Receptors Set Odor Detection Thresholds, Adam Dewan, Annika Cichy, Jingji Zhang, Kayla Miguel, Paul Feinstein, Dmitry Rinberg, Thomas Bozza

Publications and Research

In many species, survival depends on olfaction, yet the mechanisms that underlie olfactory sensitivity are not well understood. Here we examine how a conserved subset of olfactory receptors, the trace amine-associated receptors (TAARs), determine odor detection thresholds of mice to amines. We find that deleting all TAARs, or even single TAARs, results in significant odor detection deficits. This finding is not limited to TAARs, as the deletion of a canonical odorant receptor reduced behavioral sensitivity to its preferred ligand. Remarkably, behavioral threshold is set solely by the most sensitive receptor, with no contribution from other highly sensitive receptors. In addition, …

Sentiments And Asset Markets, Haritima Chauhan

Graduate Research Theses & Dissertations

The ability of sentiments to impact macroeconomic activity and financial markets is unequivocally recognized. Economists and policymakers alike, agree that the extended periods of pessimistic sentiments impeded the economic recovery after the Great Recession. Despite this knowledge, there is still much more to know about the mechanisms by which these unpredictable changes in confidence perpetuate in economic and financial systems. It is also imperative to learn how to measure the exogenous shifts in the market sentiments and the sensitivity of asset prices and macroeconomic variables to them. This dissertation examines the sentiments in two ways. Using social network data, this …

3d Global Acceleration Estimation Using Inertial Measurement Unit For Biomechanical Research, Revanth Raghuram Konda

Graduate Research Theses & Dissertations

The effects of mechanical vibrations on the body of a driver in off-road vehicles such as mining vehicles have become one of the intriguing research topics. To reduce the injuries of the operator of an off-road vehicle where vibrations of high magnitude occur, an indepth study of the nature of these vibrations must be done. The first step towards this objective is the correct estimation of acceleration of the vehicle by taking into consideration all the translational and rotational motion. The main goal of this study is the estimation of acceleration of an off-road vehicle in 3D space using an …

Language Learning In The Virtual Wild: The Influence Of Emotions On Learning Another Language In Informal Virtual Environments, Iwona Barbara Lech

Graduate Research Theses & Dissertations

This study investigates learning a foreign language in informal virtual environments (the “virtual wild”) and learners’ emotions connected to the process. Evidence suggests that incidental foreign language contact in unstructured, virtual environments can enhance second language (L2) learning, and that the use of online informal learning of language activities with students learning English as an L2 results in higher fluency, lower error rates, and greater engagement compared to learning that occurs in a traditional classroom setting. The research on online informal learning of English (OILE) aligns with the newest research in linguistics asserting that language is learned through experience with …

Quantitation Without Calibration: Response Profile As An Indicator Of Target Amount, Mrittika Debnath

Graduate Research Theses & Dissertations

Quantitative assessment of biomarkers is essential in numerous contexts from decision-making in clinical situations to food quality monitoring to the interpretation of life-science research findings. However, appropriate quantitation techniques are not as widely addressed as detection methods. One of the major challenges in biomarker’s quantitation is the need to have a calibration for correlating a measured signal to a target amount. The step complicates the methodologies and makes them less sustainable. In this work, we addressed the issue via a new strategy: relying on the position of response profile rather than absolute signal for assessment of a target nucleic acid’s …

The Role Of "Because" In Mechanistic And Teleological Explanations In Science, Lillian K.E. Asiala

Graduate Research Theses & Dissertations

In science, mechanistic and teleological explanations differ in their account for why a phenomenon occurs. A mechanistic explanation presents events within the phenomenon’s causal history, while a teleological explanation presents the function or benefit of the phenomenon. These explanation types present two different types of causal coherence relations; a cause- consequence relation for mechanistic explanations, and an enabling relationship for teleological explanations. The purpose of this study was to examine the role of the causal connective “because” in inference generation for the relations present in each explanation type. Two first experiments show that readers accept “because” as an appropriate causal …

The Use Of An Antisense Oligonucleotide (Aso) Therapy To Restore Vestibular Function In The Mouse Model Of Usher Syndrome, Tia Nicole Donaldson

Graduate Research Theses & Dissertations

Usher syndrome is an autosomal recessive disorder that results in impaired visual, auditory and vestibular function. In mouse models, Usher syndrome manifests itself through abnormal behaviors such as circling, poor auditory brainstem responses, and a decline in harmonin expression. Animals utilize several sources of information to guide spatial navigation (e.g., visual cues, vestibular input). Usher syndrome disrupts these essential sensory modalities. Recent work has demonstrated that an antisense oligonucleotide (ASO) therapy can attenuate the auditory deficit of Usher syndrome through an increase in harmonin production and correct splicing. However, it has yet to be determined if this therapy can also …

Throwing, Catching, And Balancing Of A Disk With A Disk-Shaped End Effector By Using A Two-Link Manipulator, Sandeep Reddy Erumalla

Graduate Research Theses & Dissertations

Robots are specially designed to do our needs in every field, mainly in manufacturing, automation, pharmaceuticals, and aerospace. Typically, robots are equipped with a gripper to grasp objects easily. While they function well, they can be very complex and require extensive linkages and computational power for them to operate with ease. Handling an object without a gripper is known as non-prehensile manipulation. Among non-prehensile manipulation methods, throwing, presumably followed by catching, can be used to transport objects at higher heights or longer distances than is achievable for manipulator arm with a traditional grasping manipulation method. In this thesis, throwing, catching, …

Measuring The Influence Of Bedding On Soil Nitrogen Losses And Corn Crop Nitrogen Characteristics For Fall Applied Solid Beef Cattle Manure In Eastern South Dakota, Mukesh Mehata

Electronic Theses and Dissertations

Nitrogen (N) is a major component of chlorophyll which plays a key role in the photosynthesis process in crops. The N is one of the highest demanded nutrients by all plants for their growth and reproduction. Manure or inorganic fertilizer is often applied to fulfill the crops’ N demand. However, the applied N sources have the potential of N losses in different forms from the soil volume in many ways such as ammonia (NH₃) volatilization, aerial nitrous oxide (N₂O) loss, nitrate (NO₃ --N) leaching, and runoff and/or erosion. Soil fertility, crop yield, water quality, and …

Evaluating E. Coli Particle Attachment And The Impact On Transport During High Flows, Louis Amegbletor

Electronic Theses and Dissertations

Fecal indicator bacteria, including E. coli, are the leading cause of water quality impairments within assessed waters in the United States. The source of E. coli includes WWTP, leaking sewers, animal manure, wildlife, livestock, and stream bed sediment. Storm events contribute to bacteria loading within waters through wash-in of land sources of bacteria and resuspension of bacteria within sediments. Bacteria introduced into the water column are either attached to particles or are unattached (or free-living). The goal of this study was to examine the attachment of E. coli to different particle sizes, including their impact on contributing to water …

Ca2+/Calmodulin-Dependent Protein Kinase Ii Activity And Expression In The Aged Mouse Hippocampus, James Mitchum

Honors Theses

CaM Kinase II (Ca2+/calmodulin-dependent protein kinase II) is a serine/threonine-specific protein kinase enzyme that acts as a critical regulator of learning and memory. It has previously been shown that the inability of CaMKII to maintain activation is connected to memory deficits within the aging brain. While the connection between CaMKII dysfunction and learning and memory impairments is well established, little is known about the changes that cause CaMKII dysfunction. Our research set out to investigate if CaMKII is altered during the process of aging. Specifically, we looked at activity, regulation, and stability by conducting experiments to quantify CaMKII levels of …

Food Federalism: States, Local Governments, And The Fight For Food Sovereignty, Sarah B. Schindler

Faculty Publications

Recently, a number of states have sought to withdraw or restrain local power. In this Article, which is part of the “Re-Thinking State Relevance” symposium hosted by the Ohio State Law Journal, I write about a state taking the opposite approach, and attempting to affirmatively endow its local governments with additional powers. The state is Maine, and the context is control over local food production and sales. This Article begins by addressing the emergence of the sustainable local foods movement broadly, and reasons for the growth of this movement. It then focuses more pointedly on the food sovereignty movement, considering …

The Five Functions Of Forensic Science And The Validation Issues They Raise: A Piece To Incite Discussion On Validation, D. Michael Risinger

Seton Hall Law Review

No abstract provided.

A Brief Comment On The Response By Professors Findley And Risinger To My Original Contribution To Professor Risinger’S Symposium, Edward J. Imwinkelried

Seton Hall Law Review

No abstract provided.

Defining Effective Teaching In Environmental Education: A Georgia 4-H Case Study, Lillian G. Meighan, Nicholas E. Fuhrman

Journal of Research in Technical Careers

Many studies have examined the positive learning outcomes of environmental education (EE), yet few have questioned the means for achieving such outcomes through non-formal teaching methods. Six interviews and four observations were conducted with 4-H environmental educators in Georgia. Study participants defined effective instruction in Georgia 4-H EE as novel and student-centered, where the educator utilizes their own distinct teaching styles, management of the learning environment, and extra resources while capitalizing on teachable moments. Educators worked to create both personal and environmental connections to inspire students to pursue science and environmental careers. EE trainings should prepare educators with either natural …

Safe Drinking Water In The U.S.: A Prediction Of When The Entire U.S. Population Will Have Access To Safe Drinking Water, Blossom Hamika, Haley Merrill, Zoyla Orellana

Math 365 Class Projects

This research is to show when all of the U.S. will have access to safe drinking water.

Ethical Considerations Of Ovarian And Testicular Tissue Cryopreservation In Pre-Pubertal Children Who Cannot Assent, Katarina Lee

Minnesota Journal of Law & Inequality

No abstract provided.

In Vitro Susceptibility Of Seven Antifungal Agents Againstdermatophytes Isolated In İstanbul, Rabi̇ye Altinbaş, Fatma Özakkaş, Ayşe Bariş, Deni̇z Turan, Sümeyye Şen

Turkish Journal of Medical Sciences

Background/aim: Dermatophytes are the causative agents of dermatophytosis, which is a common disease worldwide that affects the hair, skin, and nails. Dermatophytes comprise more than 40 species in 3 genera: Microsporum, Trichophyton, and Epidermaphyton. In this study, we aimed to determine the effectiveness of seven antifungal agents: amphotericin B, terbinafine, itraconazole, voriconazole, ketoconazole, miconazole, and fluconazole. Materials and methods: A sensitivity study was performed using a microdilution method in accordance with the CLSI M38-A2 standards using isolates of Trichophyton rubrum (n = 55), Microsporum canis (n = 9), and Trichophyton interdigitale (n = 2), which were identified by sequencing the …

The Histopathological Effects Of Calcium Triglyceride Bone Cement Andchitosan On The Healing Of Experimental Bone Defects, Levent Uslucan, Berkem Atalay, Cüneyt Korhan Oral, Mustafa Sami̇ Yildirim, Abdulkadi̇r Burak Çankaya

Turkish Journal of Medical Sciences

Background/aim: This study evaluated the histopathological effects of two different bone grafts, calcium triglyceride bone cement (CTBC) and chitosan, on the healing of experimental bone defects. Materials and methods: Ninety-two Sprague Dawley male rats, with a weight of 240 ± 20 g, were used. Two experimental groups that consisted of 64 rats were divided into four subgroups due to the sacrification days, which were 7, 14, 30, and 60. After creating an 8-mm- long and 1-mm-wide cortico-cancellous bone defect in the right tibia of each rat, CTBC and chitosan were applied to the bone defects. In the main group, after …

A Study Of The Factors Influencing Algebraic Problem Solving By Individuals With Visual Impairments, Sean Richards Tikkun

Graduate Research Theses & Dissertations

This study investigated the cognitive factors that impact the completion of mathematics problems, specifically algebraic-reasoning, by individuals who use tactile materials (i.e., braille) compared to those who use print materials. The inquiry investigated working memory, task time, cognitive load, efficiency, and the predictive quality of cognitive and noncognitive factors regarding task time. Research was conducted on college students enrolled at two midwestern universities. Participants completed an algebraic-reasoning task with cognitive load ratings, an operational span assessment, and a demographic survey that included a 12-item grit scale. Participants using tactile materials also completed a Nemeth Braille Code for Mathematics and Science …

Neuromuscular Control Of The Calling Apparatus In The Túngara Frog (Engystomops Pustulosus), Kiran Kaur Grewal

University of the Pacific Theses and Dissertations

Male túngara frogs can add a distinctive note ("chuck”) to their mating call. Production of the chuck involves vibrating a pair of laryngeal fibrous masses that is attached to the vocal cords. The muscular control of this mechanism remains unknown. Recent studies revealed a split in the laryngeal dilator muscle, which unveiled the deep dilator as a novel laryngeal muscle with unique attachments, innervation, and (likely) function. The deep dilator may position the fibrous masses for chuck production. The goals of this study were 1) to confirm the innervation of the novel muscle through electrophysiology; and 2) to determine the …

Behavioral Patterns Of Blinded Vs. Mock-Blinded Male Individuals In The Presence Of Females: Analysis Of The Role Of Eyes In Euphilomedes Carcharodonta Mating, Alexis Arenz

University of the Pacific Theses and Dissertations

Sexual dimorphism is exhibited throughout various organisms and takes an extensive variety of forms, although rarely does it take the form of eye-reduction within a population. This poses the question of whether this dimorphism arises due to sexual selection in order to increase reproductive success or rather from ecological selection as a result of sex-specific niche partitioning. In this case, we study an organism that displays a drastic form of sexual dimorphism, in that the males have large complex lateral eyes whereas the females lack eyes and merely have rudimentary lateral eye-spots. Euphilomedes carcharodonta is a small crustacean native to …