Digital Commons Network^™

Influenza A Virus Genomic Reassortment And Packaging, Graham Devin Williams

Arts & Sciences Graduate Student Theses and Dissertations

Influenza A viruses (IAV) are a major human and environmental pathogen. IAV successfully infects a diverse host range and adaptation of new viral strains to humans may cause pandemic events with high morbidity and mortality. As a member of the Orthomyxoviridae family, IAV inherently possesses a segmented genome, which enables a process of segment transmission between viruses following cellular co-infection, a process termed reassortment. The high rate of IAV mutation and continued co-circulation of diverse viral strains in divergent host species leads to the persistent prospect for emergence of new IAV with pandemic potential. Therefore, it is of great importance …

Venous Thromboembolism Within Professional American Sport Leagues., Meghan Bishop, Matthew Astolfi, Eric M. Padegimas, Peter F. Deluca, Sommer Hammoud

Department of Orthopaedic Surgery Faculty Papers

Background: Numerous reports have described players in professional American sports leagues who have been sidelined with a deep vein thrombosis (DVT) or a pulmonary embolism (PE), but little is known about the clinical implications of these events in professional athletes.

Purpose: To conduct a retrospective review of injury reports from the National Hockey League (NHL), Major League Baseball (MLB), the National Basketball Association (NBA), and the National Football League (NFL) to take a closer look at the incidence of DVT/PE, current treatment approaches, and estimated time to return to play in professional athletes.

Study Design: Descriptive epidemiology study.

Methods: An …

Making A Mentoring Match: Advancing The Profession Through Technology, Matthew S. Howard, Lois Sarah Marshall

General Submissions: Presentations (Oral and Poster)

The information is the attached poster allows viewers to learn about one organizations mentoring program that provides an avenue for nurses from different geographical backgrounds to stay connected and provide support.

The purpose of this project was to use new technology to provide an avenue for nurses from different geographical backgrounds to stay connected and provide support in a way that has not been done before. New web-based technology has allowed experienced nurses to connect and mentor new nurses to support their transition into their current practice.Â

Please see the attaching presentation information document for additional presentation details and references.

Soundboard Scholar No. 3: Editor's Letter, Thomas Heck

Soundboard Scholar

An introduction to the contents of this issue.

The Way We Were: A Review Of Early Efforts To Find Classical Guitar Music In Collections, Ellwood Colahan

Soundboard Scholar

This article was originally copublished online with the author's article, "Guitar Music in Collections: A New Web-Based Index Is Launched," Soundboard Scholar, no. 3 (2017), https://digitalcommons.du.edu/sbs/vol3/iss1/6.

Is There A Right To Life For The Colorado River?, Reed D. Benson

Faculty Scholarship

A recent lawsuit, declaring the Colorado River has legal rights of its own, received national attention in the New York Times and High Country News. While the lawsuit had no chance of success, it highlighted important issues.

Criterion: A Journal Of Literary Criticism, Vol. 10: Iss. 2

Criterion: A Journal of Literary Criticism

No abstract provided.

Radical Words Then And Now: The Historical And Contemporary Impact Of Elizabeth Cady Stanton's The Woman's Bible, Erika Larsen

Criterion: A Journal of Literary Criticism

No abstract provided.

The Sexual Spectrum Of The Androgynous Mind In Virginia Woolf’S Mrs. Dalloway, Sylvia Cutler-Laboulaye

Criterion: A Journal of Literary Criticism

No abstract provided.

Like A "Caged Bird": Jane Eyre's Flight To Freedom Through Imagery In Jane Eyre, Rachel Rackham

Criterion: A Journal of Literary Criticism

No abstract provided.

Ependymomas Overexpress Chemoresistance And Dna Repairrelated Proteins, Sherise D. Ferguson, Shouhao Zhou, Joanne Xiu, Yuuri Hashimoto, Nader Sanai, Lyndon Kim, Santosh Kesari, John De Groot, David Spetzler, Amy B. Heimberger

Department of Neurosurgery Faculty Papers

Background: After surgery and radiation, treatment options for ependymoma are few making recurrence a challenging issue. Specifically, the efficacy of chemotherapy at recurrence is limited. We performed molecular profiling on a cohort of ependymoma cases in order to uncover therapeutic targets and to elucidate the molecular mechanisms contributing to treatment resistance. Results: This ependymoma cohort showed minimal alterations in gene amplifications and mutations but had high expression rates of DNA synthesis and repair enzymes such as RRM1 (47%), ERCC1 (48%), TOPO1 (62%) and class III β-tublin (TUBB3) (57%), which are also all associated with chemoresistance. This cohort also had high …

Learning From Zũni War Gods Repatriating Alternative Dispute Resolution For Practice And Research, Alexandra Crampton

Social and Cultural Sciences Faculty Research and Publications

This article applies lessons learned from the Zũni people of the southwestern United States about successful and sustainable intervention as a metaphor to address common tensions among alternative dispute resolution (ADR) scholars and practitioners. These tensions are found in professionalisation, institutionalisation and identification of best practices. Through example of Zũni efforts to repatriate sacred artefacts known as Ahuy: da, I argue that ADR is an intervention that works best through direct and ongoing dialogue rather than rigid adherence to a set of standards. The problem lies in how such adherence can limit and distort rather than inform or support best …

By Any Means: How One Federal Agency Is Turning Tribal Sovereignty On Its Head, Clifton Cottrell

American Indian Law Journal

No abstract provided.

The Sioux's Suits: Global Law And The Dakota Access Pipeline, Stephen Young

American Indian Law Journal

The Sioux Tribe’s lawsuits and protests against the Dakota Access Pipelines (DAPL) received an incredible amount of international attention in ways that many Indigenous peoples’ protests have not. This article argues that attention exists because the Sioux Tribe has been at the epicenter of the Indigenous peoples’ rights movement in international law. Accordingly, they have invoked or claimed international human rights—particularly free, prior, and informed consent (FPIC)— to complicate, and perhaps destabilize, the DAPL’s development. However, the importance of their activism is not merely in claiming human rights.

Based upon a global map of law that involves multiple and overlapping …

A Hell Of A Complex: The Miscarriages Of The Federal Hydropower Licensing Regime, Derek Red Arrow Frank

American Indian Law Journal

What you are about to read is an illustration of systemic racism. Systemic racism is the current effects of statutes and policies developed through a singular and racially-charged narrative. The current hydropower relicensing regime fails to acknowledge the overarching Treaty-reserved rights of American Indian tribes while statutorily granting state and federal authorities the power to prescribe mandatory conditions on hydropower projects. This fact remains constant whether the hydropower project is within or outside a tribe’s reservation or aboriginal territory. Specifically, the Hells Canyon Complex, which rests along the Snake River, has had and continues to have enormous impacts on fisheries …

Solution Before Pollution: Mining And International Transboundary Rivers In Southeast Alaska, Britany Kee’ Ya Aa. Lindley

American Indian Law Journal

No abstract provided.

Conservation Easements: A Flexible New Tool For Washington Tribes, A Case Study Of The Lower Elwha Klallam Tribe, David P. Papiez

American Indian Law Journal

No abstract provided.

First Narrow-Band Search For Continuous Gravitational Waves From Known Pulsars In Advanced Detector Data, B. P. Abbott, R. Abbott, T. D. Abbott, F. Acernese, K. Ackley, Teviet Creighton, Mario C. Diaz, Soma Mukherjee, Volker Quetschke, Malik Rakhmanov

Physics & Astronomy Faculty Publications

Spinning neutron stars asymmetric with respect to their rotation axis are potential sources of continuous gravitational waves for ground-based interferometric detectors. In the case of known pulsars a fully coherent search, based on matched filtering, which uses the position and rotational parameters obtained from electromagnetic observations, can be carried out. Matched filtering maximizes the signal-to-noise (SNR) ratio, but a large sensitivity loss is expected in case of even a very small mismatch between the assumed and the true signal parameters. For this reason, narrow-band analysis methods have been developed, allowing a fully coherent search for gravitational waves from known pulsars …

Tensorviz: Visualizing The Training Of Convolutional Neural Network Using Paraview (Poster), Xinyu Chen, Qiang Guan, Xin Liang, Li-Ta Lo, Simon Su, Trilce Estrada, James Ahrens

Computer Science Faculty Research & Creative Works

Deep Convolutional Networks have been very successful in visual recognition tasks recently. Lots of previous works aimed to help people to get senses of why those biology-inspired networks achieved such good performances. Deconvnet[1], Guided propagation[2] and a comprehensive visualization tool box[3] can help people to see features learned at different layers of the networks. These works in some extent provided understanding and support for the biology origin of how convolutional networks emulate visual recognition tasks. However, due to the complexity of searching in very high dimensional parameter space, the whole training remains in black-boxes. Normally a large network needs weeks …

Conquering Visual Challenges While Hunting Across The Air-Water Interface; A Study Of Foraging Day Herons, Holly Brown

Doctoral Dissertations

Among several visual challenges of hunting across the air-water interface are glare, which obscures prey below the water surface; and refraction, which causes submerged prey to appear where they are not. These challenges are exacerbated by the fact that prey have visual (and other) adaptations for detecting predators. To forage successfully on underwater prey, predators must compensate. Herons are good model animals for studying how predators compensate for visual challenges at the air-water interface; they are visually-hunting, fish-eating birds. Herons also regularly tilt their long necks (“head-tilt”) while hunting, which I hypothesized could aid in compensating for glare, refraction, and …

Negotiating Motherhood And Intersecting Inequalities: A Qualitative Study Of African American Mothers And The Socialization Of Adolescent Daughters, Brandyn-Dior Mckinley

Doctoral Dissertations

'Archival abstract submitted'

Advanced Power Loss Modeling And Model-Based Control Of Three-Phase Induction Motor Drive Systems, Yiqi Liu

Doctoral Dissertations

Three-phase induction motor (IM) drive systems are the most important workhorses of many industries worldwide. This dissertation addresses improved modeling of three-phase IM drives and model-based control algorithms for the purpose of designing better IM drive systems. Enhancements of efficiency, availability, as well as performance of IMs, such as maximum torque-per-ampere capability, power density, and torque rating, are of major interest. An advanced power loss model of three-phase IM drives is proposed and comprehensively validated at different speed, load torque, flux and input voltage conditions. This model includes a core-loss model of three-phase IMs, a model of machine mechanical and …

Weaponized Citizenship: A Critical Race Theory Analysis Of U.S. Citizenship Legislation In The Pacific Unincorporated Territories, Ross Dardani

Doctoral Dissertations

This dissertation examines U.S. citizenship legislation in the U.S. Pacific unincorporated territories through Critical Race Theory’s interest-convergence thesis. I employ Derrick Bell’s theory of interest-convergence to argue that it is only when economic, cultural, political, and social interests converge to benefit the United States that U.S. lawmakers have enacted legislation to extend citizenship to the Pacific unincorporated territories (Guam, American Samoa and the Commonwealth of the Northern Mariana Islands). I also rely on Mary Dudziak’s use of interest-convergence, which she used to explain the implementation of key social reforms of the Civil Rights Movement, such as desegregation, as a model …

Design And Fabrication Of Micro-Pillar Based Piezoresistive Flow Sensors, Adimali Piyadasa

Doctoral Dissertations

This study is focused on developing a new type of micro-scale gas flow sensors to be used in critical environments such as combustion engines with high pressure high temperature gas flow and integrated micro electro mechanical applications such as lab-on-chip devices. Proposed flow sensor is based on piezoresistivity of Silicon micro column cantilever. Change in resistivity tensor due to gas flow induced stress in the piezoresistive layer results in generating of an output voltage proportional to the gas flow rate in the channel. Current results show that the anisotropic properties of the Silicon can be successfully used in the gas …

Modeling Iron Oxide Reactivity In The Environment, Nefeli Maria Bompoti

Doctoral Dissertations

Iron oxides and hydroxides are highly reactive mineral phases in natural systems since they interact with pollutants, controlling their fate and transport in the environment. Goethite (GH) and hematite (HT) are the most abundant iron minerals in nature, while ferrihydrite (FH) is a nanomineral with high surface reactivity. Subsurface transport modeling has usually represented the adsorption processes by empirical relationships, such as distribution coefficients (K_d) or isotherm equations. However, empirical approaches cannot account for variable geochemical conditions. These effects can be addressed by the mechanistic surface complexation models (SCMs). So far, the application of SCMs has been limited …

Applications Of Computability Theory To Partial And Linear Orders, Marie Nicholson

Doctoral Dissertations

Applications of computability theory to partial and linear orders.

Validasi Metode Rp-Hplc Untuk Penentuan Kadar Andrografolid Sebagai Senyawa Penanda Pada Campuran Esktrak, Anisyah Is Purwati, Prasetyawan Yunianto, Agus Supriyono

Chimica et Natura Acta

Andrografolid merupakan senyawa bioaktif dari tanaman sambiloto (Andrographis paniculata) yang berpotensi sebagai bahan obat. Kadar andrografolid dapat ditentukan menggunakan RP-HPLC. Penelitian ini bertujuan mengembangkan dan memvalidasi metode RP-HPLC untuk menentukan kadar andrografolid sebagai senyawa penanda untuk standarisasi formula obat herbal terstandar (OHT) dari campuran ekstrak tanaman sambiloto dan binahong (Andredera cordifolia). Metode RP-HPLC dikembangkan menggunakan kolom Sunfire C18 (150 × 4,6 mm, 5μm) dengan fase gerak asetonitril dan campuran 0,1% asam trifloroasetat dan metanol (90:10) secara elusi gradien serta laju alir fase gerak 1 mL/menit. Deteksi menggunakan detektor PDA pada panjang gelombang 230 nm. Andrografolid dielusi pada waktu retensi 9,77 …

Cangkang Telur Ayam Sebagai Sumber Kalsium Dalam Pembuatan Hidroksiapatit Untuk Aplikasi Graft Tulang, Atiek Rostika Noviyanti, Haryono Haryono, Rinal Pandu, Diana Rakhmawaty Eddy

Chimica et Natura Acta

Hidroksiapatit dengan struktur heksagonal merupakan biomaterial yang berpotensi sebagai implan tulang maupun gigi, karena memiliki sifat biokompatibilitas, dan bioresorbabilitas. Karakteristik kimia dan kristalinitas hidroksiapatit yang mirip dengan sifat tulang dan gigi manusia, menyebabkan kehadirannya dalam tubuh mudah diterima. Tujuan penelitian ini untuk menyintesis hidroksiapatit dengan metode basah menggunakan kalsium hasil isolasi dari cangkang telur ayam. Sintesis hidroksiapatit dilakukan dengan reaksi metode basah. Proses sintering optimum diamati dengan variasi waktu 3, 5 dan 9 jam. Karakterisasi struktur, morfologi, dan komposisi unsur hidroksiapatit masing-masing menggunakan XRD dan TM-EDX. Hidroksiapatit terbanyak diperoleh pada waktu sintering selama 5 jam, yaitu sebesar 74,74%, dengan rasio …

Penyimpanan Haloalkana Dehalogenase: Pengaruh Konsentrasi Terhadap Stabilitas Dan Aktivitas Enzim, Khomaini Hasan

Chimica et Natura Acta

Karena kebutuhan penyimpanan protein rekombinan dalam waktu yang sangat lama, berbagai macam kondisi penyimpanan telah disarankan dalam berbagai publikasi guna mempertahankan integritas struktur dan/atau aktivitas enzim asalnya. Tujuan dari penelitian ini adalah untuk mempelajari pengaruh konsentrasi protein terhadap kestabilan penyimpanan dari haloalkana dehalogenase murni. Haloalkana dehalogenase rekombinan dimurnikan dengan dua langkah pemurnian, yaitu kromatografi penukar ion  dan afinitas. Dua kondisi konsentrasi enzim diobservasi selama 4 minggu. Aktivitas enzim diuji tiap minggu yang merefleksikan kestabilan dari enzim. Hasil menunjukkan bahwa konsentrasi enzim 0.5 mg/mL, dibandingkan dengan konsentrasi 2 mg/mL, lebih mudah mengalami inaktifasi dan kehilangan aktivitas. Peningkatan aktivitas dan stabilitas enzim …

Alga Merah (Gracilaria Coronopifolia) Sebagai Sumber Fitohormon Sitokinin Yang Potensial, Saadah Diana Rachman, Zakiyah Mukhtari, R. Ukun M.S. Soedjanaatmadja

Chimica et Natura Acta

Alga  merah (Gracilaria coronopifolia) merupakan tanaman tingkat rendah berupa thallus yang tidak memiliki daun, akar dan batang sejati serta sebagian besar tumbuh pada batu di terumbu karang. Alga merah selain mengandung beberapa senyawa organik seperti polisakarida, vitamin, dan berbagai senyawa bioaktif, juga merupakan tanaman yang mengandung fitohormon sitokinin yang cukup potensial dan bermanfaat untuk pembuatan pupuk hormon/biostimulan. Penelitian ini bertujuan untuk mengisolasi dan mengidentifikasi sitokinin dari alga merah G. coronopifolia, serta mengetahui pengaruhnya terhadap pertumbuhan tanaman padi (Oryza sativa). Isolasi dan identifikasi sitokinin dimulai dengan proses maserasi menggunakan metanol 80%, ekstraksi dengan etil asetat, kromatografi adsorpsi, kromatografi lapis tipis preparatif, …