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2017

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Horizontal Cybersurveillance Through Sentiment Analysis, Margaret Hu Dec 2017

Horizontal Cybersurveillance Through Sentiment Analysis, Margaret Hu

William & Mary Bill of Rights Journal

This Essay describes emerging big data technologies that facilitate horizontal cybersurveillance. Horizontal cybersurveillance makes possible what has been termed as “sentiment analysis.” Sentiment analysis can be described as opinion mining and social movement forecasting. Through sentiment analysis, mass cybersurveillance technologies can be deployed to detect potential terrorism and state conflict, predict protest and civil unrest, and gauge the mood of populations and subpopulations. Horizontal cybersurveillance through sentiment analysis has the likely result of chilling expressive and associational freedoms, while at the same time risking mass data seizures and searches. These programs, therefore, must be assessed as adversely impacting a combination …


Have Video Gaming Revenues Led To An Increase In Municipal Services In Illinois?, Christopher Dudzinski Dec 2017

Have Video Gaming Revenues Led To An Increase In Municipal Services In Illinois?, Christopher Dudzinski

All Student Theses and Dissertations

In 2009, the Illinois General Assembly passed the Video Gaming Act, the largest gambling expansion in the state’s history. That expansion allowed locations within Illinois to have five Video Gaming Terminals (VGT) within their business, similar to the slot machines previously only seen at state casinos. These terminals arrived under much scrutiny, as scholars and citizens alike were concerned with the social negatives attached to gambling facilities. Previous research points out many of the societal connotations that comes along with Video Gaming such as negative externalities associated with bankruptcy and addiction, but has yet to analyze the impact on the …


Best Practices For Test Driven Development, Timothy Tacker Dec 2017

Best Practices For Test Driven Development, Timothy Tacker

All Student Theses and Dissertations

In his award-winning book, Test-driven Development By Example, Kent Beck wrote, "Clean code that works...is the goal of Test-driven Development (TDD)." TDD is a style of software development that first begins with the creation of tests and then makes use short, iterative development cycles until all test requirements are fulfilled. In order to provide the reader with sufficient background to understand the concepts discussed, this thesis begins by presenting a detailed description of this style of development. TDD is then contrasted with other popular styles, with a focus toward highlighting the many benefits this style offers over the others. This …


In Brownsville, A Struggle For Revitalization Without Displacement, Katherine Warren Dec 2017

In Brownsville, A Struggle For Revitalization Without Displacement, Katherine Warren

Capstones

As many parts of Brooklyn buzz with a startling rate of economic resurgence, Brownsville seems like a neighborhood left behind.

Struggling with poverty, poor health statistics, unemployment and high crime rates, and with the highest concentration of public housing in the city, it has not seen the same commercial and real estate revival as Williamsburg, Bushwick, Crown Heights and other areas of Brooklyn.

“In Brownsville, which has had challenges battling negative perceptions of this community, most of the residents are lower income and investors in the past have deemed this community as not being as good as an investment as …


Design And Analysis Of Bio-Inspired Nacelle For Current Energy Turbine, Michael Coe Dec 2017

Design And Analysis Of Bio-Inspired Nacelle For Current Energy Turbine, Michael Coe

Master's Theses

he world’s oceans contain a substantial amount of energy, stored in ocean currents and waves. Ocean current energy can be extracted using similar principles to existing wind energy platforms. A problem with such extraction methods is that the velocity of the fluid in ocean currents is too low for efficient energy generation. A potential solution to this problem is the use of a concentrator or diffuser to increase fluid velocity to the blades, but this carries with it extra costs. A more cost effective solution to this problem is presented by the use of a down flow current turbine in …


Authentication And Encryption Of Aerial Robotics Communication, Maojie Han Dec 2017

Authentication And Encryption Of Aerial Robotics Communication, Maojie Han

Master's Theses

As designed to accept custom modules, autonomous aircrafts has developed into a fast-paced industry. The remote-control system of aerial robotics is typically based on wireless communications methods, such as 2.4 GHz, 5.8 GHz, or Wi-Fi. Because the services vary with the communication method, users face different kinds of cybersecurity challenges. This thesis provides an innovative solution for the authentication and security methods in proposed aerial robotics communication network. The thesis begins with an introduction to RF drone communications. After a discussion of the MAV Link communication protocol, the thesis will focus on the differences between the existing one-to-one network and …


A Full Factorial Analysis Of Polymerization Conditions Of Sodium Alginate Beads To Determine The Effect On Diffusivity And Concentration Limit Of Tryptophan And Glucose, Allison Schulkins Dec 2017

A Full Factorial Analysis Of Polymerization Conditions Of Sodium Alginate Beads To Determine The Effect On Diffusivity And Concentration Limit Of Tryptophan And Glucose, Allison Schulkins

Master's Theses

The purpose of this work is to develop an experimental setup with associated mathematical analysis to analyze the changes in diffusivity through calcium alginate gel beads made under different polymerization conditions. The diffusivity of the solutes glucose and tryptophan was calculated by measuring the concentration change over time as solute diffused out of the alginate spheres and into the bulk. The alginate beads were generated using different polymerization conditions following a two-level, three-factor, full-factorial matrix with alginate concentration, cross-linker concentration, and cross-linking time as the factors. The diffusivities showed variations between different conditions, which were analyzed to determine the main …


System Characterizations And Optimized Reconstruction Methods For Novel X-Ray Imaging, Huifeng Guan Dec 2017

System Characterizations And Optimized Reconstruction Methods For Novel X-Ray Imaging, Huifeng Guan

McKelvey School of Engineering Graduate Student Theses & Dissertations

In the past decade there have been many new emerging X-ray based imaging technologies developed for different diagnostic purposes or imaging tasks. However, there exist one or more specific problems that prevent them from being effectively or efficiently employed. In this dissertation, four different novel X-ray based imaging technologies are discussed, including propagation-based phase-contrast (PB-XPC) tomosynthesis, differential X-ray phase-contrast tomography (D-XPCT), projection-based dual-energy computed radiography (DECR), and tetrahedron beam computed tomography (TBCT). System characteristics are analyzed or optimized reconstruction methods are proposed for these imaging modalities. In the first part, we investigated the unique properties of propagation-based phase-contrast imaging technique …


Binding Affinity And Specificity Of Sh2 Domain Interactions In Receptor Tyrosine Kinase Signaling Networks, Tom Ronan Dec 2017

Binding Affinity And Specificity Of Sh2 Domain Interactions In Receptor Tyrosine Kinase Signaling Networks, Tom Ronan

McKelvey School of Engineering Graduate Student Theses & Dissertations

Receptor tyrosine kinase (RTK) signaling mechanisms play a central role in intracellular signaling and control development of multicellular organisms, cell growth, cell migration, and programmed cell death. Dysregulation of these signaling mechanisms results in defects of development and diseases such as cancer. Control of this network relies on the specificity and selectivity of Src Homology 2 (SH2) domain interactions with phosphorylated target peptides. In this work, we review and identify the limitations of current quantitative understanding of SH2 domain interactions, and identify severe limitations in accuracy and availability of SH2 domain interaction data. We propose a framework to address some …


Identification Of Prognostic Cancer Biomarkers Through The Application Of Rna-Seq Technologies And Bioinformatics, Nathan Wong Dec 2017

Identification Of Prognostic Cancer Biomarkers Through The Application Of Rna-Seq Technologies And Bioinformatics, Nathan Wong

McKelvey School of Engineering Graduate Student Theses & Dissertations

MicroRNAs (miRNAs) are short single-stranded RNAs that function as the guide sequence of the post-transcriptional regulatory process known as the RNA-induced silencing complex (RISC), which targets mRNA sequences for degradation through complementary binding to the guide miRNA. Changes in miRNA expression have been reported as correlated with numerous biological processes, including embryonic development, cellular differentiation, and disease manifestation. In the latter case, dysregulation has been observed in response to infection by human papillomavirus (HPV), which has also been established as both oncogenic in cervical cancers and oropharyngeal cancers and favorable for overall patient survival after tumor formation. The identification of …


Multi-Scale Studies To Develop A Holistic Understanding Of Solid Fuel Combustion At Residential Scale, Sameer Patel Dec 2017

Multi-Scale Studies To Develop A Holistic Understanding Of Solid Fuel Combustion At Residential Scale, Sameer Patel

McKelvey School of Engineering Graduate Student Theses & Dissertations

Nearly 3 billion people rely on solid fuels for their cooking and heating needs, classifying them as “energy poor”. This poverty can be attributed to several factors, including a lack of resources (fuel), inefficient infrastructure (production and distribution), limited purchasing power (poverty), and ill-devised policies. Solid fuels, such as biomass, coal, and dung cakes, are burned in inefficient cookstoves. They generate products of incomplete combustion (PIC), such as CO, particulate matter (PM), and CH4, causing household air pollution (HAP) whose adverse impacts on both health and the environment have been well established.

HAP causes diseases such as chronic obstructive pulmonary …


The Inter-Laminar Shearing Effect On Wrinkle Development In Composite Forming Processes, David Sundquist Dec 2017

The Inter-Laminar Shearing Effect On Wrinkle Development In Composite Forming Processes, David Sundquist

McKelvey School of Engineering Graduate Student Theses & Dissertations

Composite materials are becoming prevalent in aerospace industries as the uniqueness of the composite structure allows the composite to be tailored specifically for individual applications. Many fabrication techniques produce defects in composite parts such as wrinkles, fiber waviness, fiber misalignment, and porosity. The driving mechanisms behind these defects occurring during forming processes are not fully understood and, thus, characterization formation of these defects in a uncured state is beneficial to optimize composite processing. This work primarily investigated the influence of how uncured pre-impregnated carbon ply properties affect the wrinkling behavior of a composite laminates. Several factors affecting composite ply forming …


Characterizing Anisotropy In Fibrous Soft Materials By Mr Elastography Of Slow And Fast Shear Waves, John Larson Schmidt Dec 2017

Characterizing Anisotropy In Fibrous Soft Materials By Mr Elastography Of Slow And Fast Shear Waves, John Larson Schmidt

McKelvey School of Engineering Graduate Student Theses & Dissertations

The general objective of this work was to develop experimental methods based on magnetic resonance elastography (MRE) to characterize fibrous soft materials. Mathematical models of tissue biomechanics capable of predicting injury, such as traumatic brain injury (TBI), are of great interest and potential. However, the accuracy of predictions from such models depends on accuracy of the underlying material parameters. This dissertation describes work toward three aims. First, experimental methods were designed to characterize fibrous materials based on a transversely isotropic material model. Second, these methods are applied to characterize the anisotropic properties of white matter brain tissue ex vivo. Third, …


Urbanization, Land Rights And Development: A Case Study Of Waterfront Communities In Lagos, Nigeria., Gideon Olaniyi Omoniyi Dec 2017

Urbanization, Land Rights And Development: A Case Study Of Waterfront Communities In Lagos, Nigeria., Gideon Olaniyi Omoniyi

Master's Theses

The aim of this study is to examine the root causes of forced evictions and displacement through the current urbanization process in Lagos, Nigeria. My particular attention is devoted to the legal complexities and how ethnolinguistic identities shape land laws, influence land tenure, and construct urban citizenship. Through this process, competing claims to land ownership provide fertile ground for forced evictions and displacement. Existing scholars suggest that poor urban residents lack rights to stay in their neighborhoods, while a powerful capitalist class has emerged and dispossessed the poor from their lands. Yet these existing approaches derived from the neoclassical and …


Articulated Indigeneity And Tourism In HawaiʻI, Erika Nielsen Dec 2017

Articulated Indigeneity And Tourism In HawaiʻI, Erika Nielsen

Master's Theses

The guiding research question for this thesis asks how Hawaiian indigeneity and self-determination are articulated within tourism spaces in Hawaiʻi. This thesis research works to uncover the nuanced ways that Hawaiian indigeneity is employed to manage and regulate tourism activities in Hawaiʻi. I seek to question the narrative that Hawaiians consent to, and prosper from, the largely unregulated mass tourism complex that has become a focal point of the post-colonial state. Native Hawaiians have actively resisted the erosion of their culture, lands, and nation through strategies that employ multiple understandings of indigeneity. We should not assume that the tourism industry …


Migrant Ridesharing Drivers In San Francisco: A Case Of Blocked Mobility?, Shireen Tofig Dec 2017

Migrant Ridesharing Drivers In San Francisco: A Case Of Blocked Mobility?, Shireen Tofig

Master's Theses

Migrants have long turned to self-employment in host country labor markets due to not only racial and ethnic prejudices, but also issues of local language proficiency and lack of recognition of the academic degree from the sending country. The taxi industry, one particular occupational niche dominated by migrants, has long been studied by scholars. However, the industry has evolved into a newer and understudied form of transportation: ridesharing. This study argues that in the case of the ridesharing industry, drivers did indeed turn to the occupation because of factors such as insufficient English language level and foreign academic degrees, but …


Cangkang Telur Ayam Sebagai Sumber Kalsium Dalam Pembuatan Hidroksiapatit Untuk Aplikasi Graft Tulang, Atiek Rostika Noviyanti, Haryono Haryono, Rinal Pandu, Diana Rakhmawaty Eddy Dec 2017

Cangkang Telur Ayam Sebagai Sumber Kalsium Dalam Pembuatan Hidroksiapatit Untuk Aplikasi Graft Tulang, Atiek Rostika Noviyanti, Haryono Haryono, Rinal Pandu, Diana Rakhmawaty Eddy

Chimica et Natura Acta

Hidroksiapatit dengan struktur heksagonal merupakan biomaterial yang berpotensi sebagai implan tulang maupun gigi, karena memiliki sifat biokompatibilitas, dan bioresorbabilitas. Karakteristik kimia dan kristalinitas hidroksiapatit yang mirip dengan sifat tulang dan gigi manusia, menyebabkan kehadirannya dalam tubuh mudah diterima. Tujuan penelitian ini untuk menyintesis hidroksiapatit dengan metode basah menggunakan kalsium hasil isolasi dari cangkang telur ayam. Sintesis hidroksiapatit dilakukan dengan reaksi metode basah. Proses sintering optimum diamati dengan variasi waktu 3, 5 dan 9 jam. Karakterisasi struktur, morfologi, dan komposisi unsur hidroksiapatit masing-masing menggunakan XRD dan TM-EDX. Hidroksiapatit terbanyak diperoleh pada waktu sintering selama 5 jam, yaitu sebesar 74,74%, dengan rasio …


Copula And Vine Modeling For Finance, L Dalla Valle Dec 2017

Copula And Vine Modeling For Finance, L Dalla Valle

School of Engineering, Computing and Mathematics

No abstract provided.


Abu Ilalang Sebagai Katalis Basa Untuk Produksi Biodiesel Dari Minyak Jelantah Dengan Metode Bera (Biodiesel Electrocatalytic Reactor), Aditya S.A. Wicaksana, Ratih Lestari, Nur Inayatullah, Yustika Yustika, Rudy S. Putra Dec 2017

Abu Ilalang Sebagai Katalis Basa Untuk Produksi Biodiesel Dari Minyak Jelantah Dengan Metode Bera (Biodiesel Electrocatalytic Reactor), Aditya S.A. Wicaksana, Ratih Lestari, Nur Inayatullah, Yustika Yustika, Rudy S. Putra

Chimica et Natura Acta

Pada penelitian ini pengabuan ilalang dilakukan pada suhu 900°C selama 8 jam dan digunakan sebagai katalis basa pada pembuatan biodiesel yang dilakukan dengan proses elektrokatalitik menggunakan elektrode grafit dengan tegangan DC 18,2 V. Proses elektrokatalitik campuran minyak jelantah, metanol dan katalis abu ilalang (2, 3 dan 5% berat katalis terhadap minyak) berlangsung pada suhu kamar dengan rasio molar minyak terhadap metanol sebesar 1:6 selama 60 menit dengan perbandingan volume pelarut THF terhadap metanol sebesar 1:1. Karakterisasi abu ilalang dilakukan dengan menggunakan XRF dan FTIR. Hasil penelitian menunjukkan bahwa kandungan mineral alkalis tertinggi terdapat pada abu akar ilalang (Ca 3,99%) yang …


The Relationship Between Student Participation In A 1:1 Laptop Initiative And Academic Achievement In A 9-12 Upper Middle Class Suburban New Jersey Public School District, Brian P. Gatens Dec 2017

The Relationship Between Student Participation In A 1:1 Laptop Initiative And Academic Achievement In A 9-12 Upper Middle Class Suburban New Jersey Public School District, Brian P. Gatens

Seton Hall University Dissertations and Theses (ETDs)

The use of laptop computers in 1:1 settings is becoming increasingly prevalent in America’s schools. As greater numbers of students are using this technology, establishing its benefits and costs is paramount, especially in light of so many demanding fiscal situations. This study used quantitative research and analysis to measure the benefits and costs of such an expansive distribution of technology. It seeks to answer the question of the worth of such a large-scale adoption.

This study explored the relationship between the use of a laptop computer on a 1:1 basis for the purpose of academic instruction and its connection …


Characterization Of Structural Dynamics Of The Human Head Using Magnetic Resonance Elastography, Andrew Arun Badachhape Dec 2017

Characterization Of Structural Dynamics Of The Human Head Using Magnetic Resonance Elastography, Andrew Arun Badachhape

McKelvey School of Engineering Graduate Student Theses & Dissertations

In traumatic brain injury (TBI), the skull-brain interface, composed of three meningeal layers: the dura mater, arachnoid mater, and pia mater, along with cerebrospinal fluid (CSF) between the layers, plays a vital role in transmitting motion from the skull to brain tissue. Magnetic resonance elastography (MRE) is a noninvasive imaging modality capable of providing in vivo estimates of tissue motion and material properties. The objective of this work is to augment human and phantom MRE studies to better characterize the mechanical contributions of the skull-brain interface to improve the parameterization and validation of computational models of TBI. Three specific aims …


Comparison Of The Bi-Directional Performance Of Micro-Channel Sieve And Thin-Film Time Peripheral Nerve Interfaces, Robert Coker Dec 2017

Comparison Of The Bi-Directional Performance Of Micro-Channel Sieve And Thin-Film Time Peripheral Nerve Interfaces, Robert Coker

McKelvey School of Engineering Graduate Student Theses & Dissertations

Sophisticated motorized prosthetic limbs contain multiple degrees of freedom of motion as well as embedded pressure and angle transducers to provide sensory feedback in amputees. Although several central neural recording and stimulation modalities exist for both controlling these motions and providing sensory feedback from a prosthetic limb, directly interfacing the peripheral nerves which originally innervated the limb has many advantages. A difficulty with this bi-directional approach is that electrically stimulating axons to provide haptic feedback creates stimulation artifacts at neighboring recording sites within the nerve that are several orders of magnitude larger than the electroneurogram used for control. In this …


Locality-Aware Concurrency Platforms, Jordyn Chrystopher Raymond Maglalang Dec 2017

Locality-Aware Concurrency Platforms, Jordyn Chrystopher Raymond Maglalang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Modern computing systems from all domains are becoming increasingly more parallel. Manufacturers are taking advantage of the increasing number of available transistors by packaging more and more computing resources together on a single chip or within a single system. These platforms generally contain many levels of private and shared caches in addition to physically distributed main memory. Therefore, some memory is more expensive to access than other and high-performance software must consider memory locality as one of the first level considerations.

Memory locality is often difficult for application developers to consider directly, however, since many of these NUMA affects are …


Accurate Determination And Application Of Local Strain For Studying Tissues With Gradients In Mechanical Properties, John Boyle Dec 2017

Accurate Determination And Application Of Local Strain For Studying Tissues With Gradients In Mechanical Properties, John Boyle

McKelvey School of Engineering Graduate Student Theses & Dissertations

Determination of the mechanical behavior of materials requires an understanding of deformation during loading. While this is traditionally accomplished in engineering by examining a force displacement curve for a whole sample, these techniques implicitly ignore local geometric complexities and local material inhomogeneities commonly found in biologic tissues. Techniques such as normalized cross correlation have been classically applied to address this issue and resolve deformation at the local level; however, these techniques have proven unreliable when deformations become large, if the sample undergoes a rotation, and/or if strain fields become incompatible (e.g. at or near failure).

Presented here is a toolbox …


Coupling Of Oxidation-Reduction Reactions Of Chromium, Iron And Manganese: Implications For The Fate And Mobility Of Chromium In Aquatic Environments, Chao Pan Dec 2017

Coupling Of Oxidation-Reduction Reactions Of Chromium, Iron And Manganese: Implications For The Fate And Mobility Of Chromium In Aquatic Environments, Chao Pan

McKelvey School of Engineering Graduate Student Theses & Dissertations

Both within the United States and internationally, hexavalent chromium (Cr(VI)) is a contaminant of concern in drinking water supplies. The U.S. Environmental Protection Agency is considering a Cr(VI)-specific standard. Thus improved technologies for Cr(VI) removal in drinking water are needed. Iron electrocoagulation for Cr(VI) removal was examined at conditions directly relevant to drinking water treatment, and humic acid (HA) affects the performance of electrocoagulation in multiple ways. The success of the chromium treatment or remediation also relies on the stability of the Cr(III)-containing solids with respect to reoxidation under groundwater conditions. Manganese is ubiquitous in aquatic and terrestrial environments, and …


Multiscale Imaging Of The Mouse Cortex Using Two-Photon Microscopy And Wide-Field Illumination, Jonathan Richard Bumstead Dec 2017

Multiscale Imaging Of The Mouse Cortex Using Two-Photon Microscopy And Wide-Field Illumination, Jonathan Richard Bumstead

McKelvey School of Engineering Graduate Student Theses & Dissertations

The mouse brain can be studied over vast spatial scales ranging from microscopic imaging of single neurons to macroscopic measurements of hemodynamics acquired over the majority of the mouse cortex. However, most neuroimaging modalities are limited by a fundamental trade-off between the spatial resolution and the field-of-view (FOV) over which the brain can be imaged, making it difficult to fully understand the functional and structural architecture of the healthy mouse brain and its disruption in disease. My dissertation has focused on developing multiscale optical systems capable of imaging the mouse brain at both microscopic and mesoscopic spatial scales, specifically addressing …


Two-Component Hydrogel As Biomimetic Vitreous Substitutes, Sruthi Santhanam Dec 2017

Two-Component Hydrogel As Biomimetic Vitreous Substitutes, Sruthi Santhanam

McKelvey School of Engineering Graduate Student Theses & Dissertations

The vitreous humor of the eye is a biological hydrogel principally composed of fibrillary collagen interspersed with semi-flexible polyelectrolyte, hyaluronic acid (HA). Certain pathological conditions necessitate its removal and replacement. Current vitreous substitutes, such as silicone oils and perfluorocarbons, are hydrophobic, do not resemble the properties of the vitreous, and have known complications. An ideal vitreous substitute should have properties of the natural vitreous, perform its functions, and be biocompatible in the eye. Inspired by the structure and composition of the natural vitreous, we used bio-mimicry to develop an injectable two-component hydrogel. The hydrogel is composed of a fibrillary gellan, …


Mechanics Of The Developing Brain: From Smooth-Walled Tube To The Folded Cortex, Kara Ellspermann Garcia Dec 2017

Mechanics Of The Developing Brain: From Smooth-Walled Tube To The Folded Cortex, Kara Ellspermann Garcia

McKelvey School of Engineering Graduate Student Theses & Dissertations

Over the course of human development, the brain undergoes dramatic physical changes to achieve its final, convoluted shape. However, the forces underlying every cinch, bulge, and fold remain poorly understood. This doctoral research focuses on the mechanical processes responsible for early (embryonic) and late (preterm) brain development.

First, we examine early brain development in the chicken embryo, which is similar to human at these stages. Research has primarily focused on molecular signals to describe morphogenesis, but mechanical analysis can also provide important insights. Using a combination of experiments and finite element modeling, we find that actomyosin contraction is responsible for …


Regulation Of Gene Expression By Rna Binding Proteins And Micrornas, Kyle Cottrell Dec 2017

Regulation Of Gene Expression By Rna Binding Proteins And Micrornas, Kyle Cottrell

Arts & Sciences Graduate Student Theses and Dissertations

Regulation of gene expression is essential to life. Post-transcriptional regulation of gene expression is a complex process with many inputs that lead to changes in localization, translation and stability of mRNAs. The translation and stability of many mRNAs is regulated by cis-elements, such as mRNA-structure or codon optimality; and by trans-acting factors such as RBPs and miRNAs. Here I report on the complex interactions between RBPs, miRNAs and characteristics of their target mRNAs in respect to effects on translation and RNA stability.Using a reporter based approach we studied modulation of microRNA-mediated repression by various mRNA characteristics. We observed the influence …


Functional Bio-Nano Hybrids Through A Precise Control Of Interfacial Interactions At The Nanoscale, Sirimuvva Tadepalli Dec 2017

Functional Bio-Nano Hybrids Through A Precise Control Of Interfacial Interactions At The Nanoscale, Sirimuvva Tadepalli

McKelvey School of Engineering Graduate Student Theses & Dissertations

During the course of evolution, proteins have evolved to perform exquisite functions including structural support, signal transduction, actuation, sensing, catalysis, trafficking, gating, light-harvesting, charge transfer, molecular recognition, self-assembly, self-organization, or combinations of two or more of these functions. A precise control and manipulation of the structure and function of proteins is conceivable with the advent of nanotechnology, which has facilitated the integration of nanomaterials with functional biomolecules to realize bio-nano hybrids with synergistically enhanced functionalities.

At the genesis of bionanotechnology, a paucity in the fundamental understanding of the bio-nano interfaces is a grave impediment to the progress of the field. …