Digital Commons Network^™

Masson Engineering Pumpkin-Shaped Molecular Transporters, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Pretargeting Of Internalizing Trastuzumab And Cetuximab With A 18f-Tetrazine Tracer In Xenograft Models, Outi Keinänen, Kimberly Fung, Jacob Pourat, Vilma Jallinoja, Delphine Vivier, Nagavara Kishore Pillarsetty, Anu J. Airaksinen, Jason S. Lewis, Brian M. Zeglis, Mirkka Sarparanta

Publications and Research

Background: Pretargeting-based approaches are being investigated for radioimmunoimaging and therapy applications to reduce the effective radiation burden to the patient. To date, only a few studies have used short-lived radioisotopes for pretargeting of antibodies, and such examples with internalizing antibodies are even rarer. Herein, we have investigated pretargeting methodology using inverse electron-demand Diels-Alder (IEDDA) for tracing two clinically relevant, internalizing monoclonal antibodies, cetuximab and trastuzumab.

Results: Bioorthogonal reaction between tetrazine and trans-cyclooctene (TCO) was used for tracing cetuximab and trastuzumab in vivo with a fluorine-18 (t½ = 109.8 min) labelled tracer. TCO-cetuximab or TCO-trastuzumab was administered 24, 48, or 72 …

Additive Manufacturing Of Biocompatible Thin Polymeric Tubular Structure, Anant Bhusal

Electronic Theses and Dissertations Archive

Additive manufacturing (AM) or 3D printing may be used to fabricate synthetic artery for use in, for example, coronary artery bypass surgery. Structurally, the artery comprises the intima layer and two other layers. Thus, we have suggested that a novel approach is to use different AM methods to fabricate the different parts of the artery and to devise a way to suitably join them. In the present work, we concentrated on the fabrication of a thin polymeric tubular structure that would mimic the intima. None of three in-house AM machines produced such a structure with the requisite thickness (0.074 mm). …

When Institutions Of Higher Ed Fail, Aldemaro Romero Jr.

Publications and Research

Some may think that the only sign of a college or university failing is when it closes. And that has certainly happened to some small, private colleges that have gone bankrupt in the last few years. Yet, failure has many faces and comes in many degrees.

We can say that colleges and universities fail when the quality of education they offer is not rigorous, regard- less of what some regulatory agencies might say. Or when they promise to prepare students for jobs that no longer exist. Luring new students based on rankings, amenities, and other forms of non-academic qualities is …

Copyright Infringement In Sound Recording: How Courts And Legislatures Can Get In Vogue In A Post-Ciccone World, Kristen B. Kennedy

Journal of Law and Policy

Music sampling is a legally complex and ambiguous area, with staggeringly high costs attached for copyright infringers. The legality of sampling frequently depends upon what jurisdiction the inquiry into the sampling takes place in, and has been guided by inconsistently applied doctrines of fair use, de minimis, and copyright infringement. The Ninth Circuit’s decision in VMG Salsoul v. Ciccone has dramatically highlighted these inconsistencies. This note suggests a four-part solution to resolve the tensions in copyrightable sound recordings magnified by the recent circuit split created by VMG Salsoul v. Ciccone. It incorporates elements of de minimis and fair use, a …

Effect Of Sonication On The Viscosity Of Reconstituted Skim Milk Powder And Milk Protein Concentrate As Influenced By Solids Concentration, Temperature And Sonication, Vidita K. Desphande, M. K. Walsh

Nutrition, Dietetics, and Food Sciences Faculty Publications

Skim milk powder (SMP) and milk protein concentrates (MPCs) are manufactured by evaporation followed by spray drying and are widely used as functional and nutritional ingredients. This study investigated the effects of temperature (40–60 °C) and total solids content (TS) on the viscosity of reconstituted MPC (rMPC) (≥30% TS) and SMP (rSMP) (≥46% TS) in laboratory conditions. Additionally, the influence of sonication in batch (70% amplitude) and flow through systems (90% amplitude) was studied in a laboratory setting. The viscosity increased for all treatments with an increase in TS and decreased with an increase in temperature. Overall, sonication in both …

Recent Case Decisions

Oil and Gas, Natural Resources, and Energy Journal

No abstract provided.

A Reexamination And Reformulation Of The Habendum Clause Paying Quantities Standard Under Oil And Gas Leases, Alex Ritchie

Oil and Gas, Natural Resources, and Energy Journal

No abstract provided.

European Energy Security, American Lng, And The Global Natural Gas Marketplace, Dr. Christopher S. Kulander

Oil and Gas, Natural Resources, and Energy Journal

No abstract provided.

Automated Fiber Network Monitoring, Bravishma Narayan

Defensive Publications Series

Telecommunication infrastructure providers, e.g., fiber network providers, benefit from accurate knowledge of the network footprint. This disclosure describes techniques to automatically monitor fiber networks. Datasets of fiber network information are hosted on suitable platforms, and can be easily customized. Network footprint, including information about the handholes and their adjacent handholes, provided by the network planner is captured as a dataset. Network splicing data points are identified and stored per customer along with their duct/microduct and ring information as a dataset. A breadth first search technique is used to analyze the datasets and provide information about usage of pairs and cores. …

Telesurgery: Surgery In The Digital Age, Dylan J. Cahill

Dartmouth Undergraduate Journal of Science

The dawn of the digital age has transformed the way we now receive and provide healthcare. Today, providers have instant access to all of their patients’ information, just as patients can connect with their providers on their smartphones in minutes from nearly anywhere in the world.

Lyme Disease: An Influential Outdoor Hazard, Kevin Kang

Dartmouth Undergraduate Journal of Science

Lyme disease is an important, common illness in New England. A relatively new illness, it was discovered about forty years ago in the town of Lyme, Connecticut. Now, it has become the most common vector-transmitted illness in the United States, with over 30,000 cases annually. Lyme disease arises when a bacterium is transmitted to a human via deer tick bite, so those of us involved in outdoor sports are most likely to contract the disease. Inhabitants of New England and the northeastern U.S. are most vulnerable to the disease, as 95% of Lyme Disease cases occur in only 14 out …

Towards Simulating The Human Brain, Logan T. Collins

Dartmouth Undergraduate Journal of Science

The human brain has been described as “the most complex object in the universe.” Its meshwork of 86 billion neurons,84 billion glial cells, and over 150 trillion synapses may seem intractable. Nonetheless, efforts to comprehensively map, understand, and even computationally reproduce this structure are underway. Large collectives of researchers have come together, working in concert towards these goals. The Human Brain Project (HBP) and its precursor, the Blue Brain Project, have spearheaded the brain simulation goal.Some other notable organizations include the China Brain Project, the BRAIN Initiative. On a scale which parallels the space program and the Human Genome Project, …

The Toxicity Of Nanoparticles Depends On Multiple Molecular And Physicochemical Mechanisms, Yue-Wern Huang, Melissa Cambre, Han-Jung Lee

Biological Sciences Faculty Research & Creative Works

Nanotechnology is an emerging discipline that studies matters at the nanoscale level. Eventually, the goal is to manipulate matters at the atomic level to serve mankind. One growing area in nanotechnology is biomedical applications, which involve disease management and the discovery of basic biological principles. In this review, we discuss characteristics of nanomaterials, with an emphasis on transition metal oxide nanoparticles that influence cytotoxicity. Identification of those properties may lead to the design of more efficient and safer nanosized products for various industrial purposes and provide guidance for assessment of human and environmental health risk. We then investigate biochemical and …

Timber Talk, Vol. 55, No. 4, December 2017

Timber Talk: Nebraska Forest Industry Newsletter

Lumber Market Reports: Northern, Southern, Appalachian

Hardwood Lumber Prices: Green, Kiln-Dried, Pallet Lumber, Ties (7x9)

Tribal Walnut Timber Harvesting Expanding in Nebraska, by Anthony Crill, Bureau of Indian Affairs

To Influence Buyers, Tell Stories, by Paul Reilly, Reilly Sales Training

Green Star Energy Group, South Sioux City Celebrates Bioenergy Day

Welcome Kristina Hughes

Nebraska Forest Industry Spotlight: Native Lumber & Sawmill, Litchfield

Wood Businesses Work to Increase Marketing Skills

Trading Post

A Comparative Analysis Of Three Major Transfer Airports In Northeast Asia Focusing On Incheon International Airport Using A Conjoint Analysis, Tae Won Chung, Yong Joo Lee, Hyun Mi Jang

Finance and Supply Chain Faculty Scholarship

Due mainly to the privatization and commercialization of airline companies and deregulation of the aviation rules, the demand for air transport has continuously been increasing. Airport authorities state that transfer passengers, who contribute to the large portion of the airports’ profits, are gaining much more importance, particularly in the Northeast Asia region where the air transport industry is very vital. Therefore, this study aims to investigate the competitiveness of IIA (Incheon International Airport) with other major airports located in Northeast Asia in passenger transfers made between Southeast Asia and China to North America using Conjoint Analysis. Results have indicated that …

Garden Building Design Project, Gena Farley, Vanessa Villanueva, Jayanne Asuncion

Building Information Modeling Final Projects

Final project from the EMGT 193/293 Building Information Modeling (BIM) course in the School of Engineering and Computer Science as part of the Bachelor of Science in Engineering Management degree. A student group designed and modeled a one-story building to house the Pacific Garden Program on campus.

Robb Garden Building, Joseph Cliscagne, Joseph Prescott, Tamara Turton, Saima Uz-Zaman

Building Information Modeling Final Projects

Final project from the EMGT 193/293 Building Information Modeling (BIM) course in the School of Engineering and Computer Science as part of the Bachelor of Science in Engineering Management degree. A student group designed and modeled a one-story building to house the Pacific Garden Program on campus.

Student Movement - Issue 11, Andrews University

Student Movement v. 102 (2017-2018)

Student Movement, Issue 11, 2017

Ub Law Forum Volume 32 Number 1 Winter 2017-18, University At Buffalo School Of Law

UB Law Forum

No abstract provided.

Entering Class Profile, Ub Law Forum

UB Law Forum

No abstract provided.

Two New Faculty Books, Ub Law Forum

UB Law Forum

No abstract provided.

Enhancing Ontario’S Rural Infrastructure Preparedness: Inter-Community Service Sharing In A Changing Climate — Interim Report 1: Key Informant Interview Results, Bryce Gunson, Brenda Murphy

Social and Environmental Justice Faculty Publications

The purpose of this study is to develop a climate change (CC) prepared inter-community service sharing strategy (ICSS) targeted to rural Ontario communities that capitalizes on infrastructure assessments that are undertaken through the asset management process (AMP). AMP is defined by the Ontario government as “…. the process of making the best possible decisions regarding the building, operating, maintaining, renewing, replacing and disposing of infrastructure assets. It helps prioritize infrastructure needs and ensures that investments are made in the right place and at the right time to minimize future repair and rehabilitation costs.” The objective of AMPs are to maximize …

Rwu Approves Campus Location For New Seccm Labs, Edward Fitzpatrick

Featured News Story

With Trustees' approval, RWU plans to break ground in spring on School of Engineering, Computing and Construction Management Labs.

The Cost Of Experiencing Everyday Legal Problems Related To Loss Of Employment And Loss Of Housing, Lisa Moore, Ab Currie, Nicole Aylwin, Trevor C. W. Farrow

Canadian Forum on Civil Justice

In 2014, the Canadian Forum on Civil Justice (CFCJ) conducted a national survey to determine the costs, extent and consequences of serious civil and family justice problems experienced by the Canadian public. Findings from the CFCJ’s national “Everyday Legal Problems and the Cost of Justice in Canada” survey (Cost of Justice survey) confirm that civil and family legal problems result in significant monetary costs to the individuals who experience them as well as to the publicly funded services that individuals access for support when dealing with legal problems. With Canadians spending almost as much to resolve their legal problems as …

Achieving Totally Local Anticoagulation On Blood Contacting Devices, Rana Gbyli, Anna Mercaldi, Harihara Sundaram, Kagya Amoako

Mechanical and Industrial Engineering Faculty Publications

The recent years have witnessed an increased activity in biocompatibility research aimed at limiting biomaterial-induced blood coagulation. From 2008 to 2016, a total of $36,946,764.00 USD was awarded in grants to 213 research proposals and as large as 50.4% ($18,627,854.00) of that award monies were distributed to 101 proposals over the fiscal years of FY14 to FY16 alone. However, the complexity in blood responses to biomaterials, variability in blood function between individuals and animal species, and differences in medical device application and test setting all continue to pose difficulties in making a breakthrough in this field. This review focuses on …

Building For Good, Merrimack College

Merrimack Magazine

No abstract provided.

The Cresset (Vol. Lxxxi, No. 2, Advent/Christmas), Valparaiso University

The Cresset (archived issues)

No abstract provided.

Mole Street Journal, December 2017, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Wall Fellows Newsletter, Volume 6, Issue 2, Winter 2017, Coastal Carolina University

Wall Fellows Newsletter

Newsletter of the Wall Fellows Program in the E. Craig Wall Sr. College of Business Administration.