Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Life Sciences (7616)
- Medicine and Health Sciences (4307)
- Social and Behavioral Sciences (3571)
- Physical Sciences and Mathematics (3037)
- Education (2332)
-
- Arts and Humanities (1939)
- Biology (1882)
- Engineering (1629)
- Law (1311)
- Psychology (1140)
- Ecology and Evolutionary Biology (974)
- Medical Specialties (953)
- Higher Education (861)
- Entomology (855)
- Environmental Sciences (852)
- Animal Sciences (822)
- Medical Sciences (777)
- Chemistry (764)
- Plant Sciences (759)
- Biochemistry, Biophysics, and Structural Biology (758)
- Public Health (623)
- Sociology (592)
- Genetics and Genomics (562)
- Cell and Developmental Biology (501)
- Agriculture (493)
- Diseases (400)
- Computer Sciences (388)
- Biochemistry (384)
- History (372)
- Religion (368)
- Institution
-
- University of Nebraska - Lincoln (1414)
- University of Kentucky (722)
- University of South Florida (615)
- Valparaiso University (610)
- Utah State University (570)
-
- Louisiana State University (549)
- TÜBİTAK (522)
- City University of New York (CUNY) (487)
- University of Plymouth (487)
- Washington University School of Medicine (461)
- Chulalongkorn University (410)
- Brigham Young University (379)
- Nova Southeastern University (375)
- University of Rhode Island (351)
- University of New Mexico (349)
- Ohio University (336)
- Virginia Commonwealth University (333)
- Walden University (312)
- University of New Hampshire (305)
- West Virginia University (298)
- Georgia Southern University (288)
- University of South Carolina (284)
- University of Arkansas, Fayetteville (272)
- University of Montana (272)
- Portland State University (263)
- Purdue University (258)
- Thomas Jefferson University (248)
- University of Tennessee, Knoxville (243)
- Clemson University (233)
- University of Alabama at Birmingham (231)
- Keyword
-
- Humans (390)
- Female (219)
- Male (213)
- Animals (200)
- Biological Sciences (189)
-
- Education (163)
- Gender (162)
- Cancer (134)
- Climate change (130)
- Biology (123)
- Northern bobwhite (117)
- Colinus virginianus (112)
- Newspaper (110)
- Obesity (107)
- Mice (105)
- Stress (105)
- Adult (99)
- Conservation (96)
- Inflammation (91)
- Depression (90)
- Genetics (89)
- Ecology (88)
- Psychology (87)
- Student newspaper (86)
- Environmental & Plant Biology (84)
- Georgia Southern University (84)
- Biological Sciences Events (83)
- Higher education (80)
- Middle Aged (80)
- Evolution (78)
- Publication
-
- Theses and Dissertations (952)
- Faculty Publications (585)
- Electronic Theses and Dissertations (572)
- The Great Lakes Entomologist (569)
- Open Access Publications (447)
-
- Chulalongkorn University Theses and Dissertations (Chula ETD) (408)
- All Forum Articles (315)
- Walden Dissertations and Doctoral Studies (301)
- Dissertations (258)
- National Quail Symposium Proceedings (228)
- Publications and Research (228)
- Honors Theses (213)
- USF Tampa Graduate Theses and Dissertations (205)
- Open Access Dissertations (203)
- Articles (194)
- Master's Theses (181)
- Doctoral Dissertations (165)
- School of Biological and Marine Sciences (165)
- Food and Machinery (164)
- Theses (158)
- Dissertations, Theses, and Capstone Projects (154)
- Graduate Theses, Dissertations, and Problem Reports (ETD) (152)
- Graduate Theses and Dissertations (148)
- New Mexico Quarterly (141)
- Masters Theses (128)
- Articles, Abstracts, and Reports (127)
- Turkish Journal of Zoology (117)
- United States Department of Agriculture Wildlife Services: Staff Publications (115)
- Browse All News (113)
- Faculty Scholarship (113)
- Publication Type
Articles 6271 - 6300 of 30193
Full-Text Articles in Entire DC Network
Daily Eastern News: September 08, 2017, Eastern Illinois University
Daily Eastern News: September 08, 2017, Eastern Illinois University
September
No abstract provided.
Pteronura Brasiliensis (Carnivora: Mustelidae), Paula Noonan, Siobhan Prout, Virginia Hayssen
Pteronura Brasiliensis (Carnivora: Mustelidae), Paula Noonan, Siobhan Prout, Virginia Hayssen
Biological Sciences: Faculty Publications
Pteronura brasiliensis (Zimmermann, 1780), the giant otter, is the largest freshwater otter. Found in South America, it inhabits slow-moving rivers and creeks and feeds predominantly on fish. Extinct in the southern portions of its former range, P. brasiliensis is listed as "Endangered" by the International Union for Conservation of Nature and Natural Resources. Threats to P. brasiliensis include habitat destruction, illegal hunting, and disease.
Using Ya Fiction To Build Interest In Stem With Teen Girls, Melissa Cast-Brede
Using Ya Fiction To Build Interest In Stem With Teen Girls, Melissa Cast-Brede
Teacher Education Faculty Proceedings & Presentations
If Hunger Games can inspire young women to take up the bow and arrow, then surely other young adult (YA) titles can inspire enthusiasm for STEM (science, technology, engineering, and math). This program will discuss the role of YA fiction in teen development and specific YA titles to encourage STEM interests with teen girls.
Acute And Late Toxicities Of Concurrent Chemoradiotherapy For Locally-Advanced Non-Small Cell Lung Cancer., Vivek Verma, Charles B 2nd Simone, Maria Werner-Wasik
Acute And Late Toxicities Of Concurrent Chemoradiotherapy For Locally-Advanced Non-Small Cell Lung Cancer., Vivek Verma, Charles B 2nd Simone, Maria Werner-Wasik
Department of Radiation Oncology Faculty Papers
For patients with unresectable locally-advanced non-small cell lung cancer (LA-NSCLC), concurrent chemoradiotherapy improves overall survival as compared to sequential chemotherapy and radiation therapy, but is associated with higher rates of toxicities. Acute, clinically significant esophagitis or pneumonitis can occur in one in five patients. The risks of esophagitis and pneumonitis can impact the decision to deliver concurrent therapy and limit the total dose of radiation therapy that is delivered. Hematologic toxicities and emesis are common toxicities from systemic therapies for LA-NSCLC and can result in delaying chemotherapy dosing or chemotherapy dose reductions. Late treatment morbidities, including pulmonary fibrosis and cardiac …
Enhancing Phylogenetic Resolution With Taxonomic And Geographic Characterization Of The Chilean Species Of The Cicada Genus Tettigades, Katherine Nazario
Enhancing Phylogenetic Resolution With Taxonomic And Geographic Characterization Of The Chilean Species Of The Cicada Genus Tettigades, Katherine Nazario
Master's Theses
The Patagonian cicada genus Tettigades, although abundant and diverse, was poorly documented until Torres (1958) reviewed the species of the genus, describing 17 new species and redescribing others. His review provided useful insights on variation and distribution of species in the genus. However, despite Torres’ efforts, some species descriptions remained vague and many lacked descriptions of morphological variation within or among populations.
The goal of this thesis is to compile, evaluate, and integrate previous work with new data to serve as a reference for future studies of this genus. Morphological, geographical, and molecular data are combined in order to treat …
September 8, 2017, The Dakota Student
September 8, 2017, The Daily Mississippian
September 8, 2017, The Daily Mississippian
Daily Mississippian (all digitized issues)
No abstract provided.
Reclassification Of Halothiobacillus Hydrothermalis And Halothiobacillus Halophilus To Guyparkeria Gen. Nov. In The Thioalkalibacteraceae Fam. Nov., With Emended Descriptions Of The Genus Halothiobacillus And Family Halothiobacillaceae, Rich Boden
School of Biological and Marine Sciences
The genus Halothiobacillus contains four species of obligate autotrophs with validly published names, of which Halothiobacillus halophilus and Halothiobacillus hydrothermalis are very distant from the type species – on the basis of the 16S rRNA gene, they have 90.7 % and 90.9 % identity to that of the type species, Halothiobacillus neapolitanus . As these values fall below the Yarza cut-off for the rank of genus, and these two species also show no clear affiliation to the closely related genus Thioalkalibacter , a polyphasic study was undertaken to determine if they represent a separate genus. Unlike Halothiobacillus spp. sensu stricto, …
Informed Systems At Pacific University Libraries: Information Exchange For Knowledge Creation, Mary M. Somerville, Robin Imhof
Informed Systems At Pacific University Libraries: Information Exchange For Knowledge Creation, Mary M. Somerville, Robin Imhof
First-Year Honors Program Research Seminars
University of the Pacific Libraries initiated a workplace systems design initiative in 2016. The participatory action research project engaged co-workers in data collection, analysis, interpretation, and reflection. Results furthered understanding about using information to learn in job-related information use stories. These insights guided co-design of systems for information exchange and conditions for workplace learning. Now, information centered, technology enabled, and human mediated communication systems and professional practices support co-worker engagement in re-invention of library facilities, services, and resources.
Local results are presented within the theoretical framework of Informed Systems, in development for over a decade by a distributed international research …
Recasting The Founding Fathers: The Tea Party Movement, Neoliberalism, And American Myth, Calvin Coker
Recasting The Founding Fathers: The Tea Party Movement, Neoliberalism, And American Myth, Calvin Coker
Speaker & Gavel
This article analyzes representative texts from the Tea Party Movement (TPM), a conservative American political movement, to demonstrate the TPM uses the myth of the Founding Fathers as an argumentative strategy to craft and justify a sanitary neoliberal political project. The necessity of such of a project lies in the underlying democratic crisis of neoliberalism, a crisis navigated by the TPM through strategic use of political myth. Neoliberal policies require, in many instances, democratic consent, though those policies often serve to disenfranchise many of the groups supporting them. This essay argues the TPM uses myth for the purpose of creating …
Climate, Wildfire, And Erosion Ensemble Foretells More Sediment In Western Usa Watersheds, John B. Sankey, Jason Kreitler, Todd J. Hawbaker, Jason L. Mcvay, Mary Ellen Miller, Erich R. Mueller, Nicole M. Vaillant, Scott E. Lowe, Temuulen T. Sankey
Climate, Wildfire, And Erosion Ensemble Foretells More Sediment In Western Usa Watersheds, John B. Sankey, Jason Kreitler, Todd J. Hawbaker, Jason L. Mcvay, Mary Ellen Miller, Erich R. Mueller, Nicole M. Vaillant, Scott E. Lowe, Temuulen T. Sankey
Michigan Tech Research Institute Publications
The area burned annually by wildfires is expected to increase worldwide due to climate change. Burned areas increase soil erosion rates within watersheds, which can increase sedimentation in downstream rivers and reservoirs. However, which watersheds will be impacted by future wildfires is largely unknown. Using an ensemble of climate, fire, and erosion models, we show that postfire sedimentation is projected to increase for nearly nine tenths of watersheds by >10% and for more than one third of watersheds by >100% by the 2041 to 2050 decade in the western USA. The projected increases are statistically significant for more than eight …
Western News, September 7, 2017, Western Michigan University
Western News, September 7, 2017, Western Michigan University
Western News (1972-2018)
Story highlights: Presidential inauguration set for Sept. 15, Make a Difference staffers to be feted at convocation, Meeting set to gain input on updating valley housing, Seita program named finalist for award, Magazine yet again lauds WMU with top-100 ranking, Interim provost is among high-level appointments, Montgomery hits the ground running as WMU’s ninth president, On Campus with Catherine VanDerMaas
Course Catalog 2017-18, Wellesley College
Course Catalog 2017-18, Wellesley College
The Wellesley College Catalogs
No abstract provided.
A Genome Sequence Of Oceanimonas Doudoroffii Atcc 27123t, Marc A. Brennan, Ariel M. Trachtenberg, William D. Mcclelland, Kyle S. Maclea
A Genome Sequence Of Oceanimonas Doudoroffii Atcc 27123t, Marc A. Brennan, Ariel M. Trachtenberg, William D. Mcclelland, Kyle S. Maclea
Life Sciences Faculty Scholarship
Oceanimonas doudoroffii ATCC 27123T is an obligately aerobic Gram-negative rod of the class Gammaproteobacteria. It was first isolated from surface seawater off the coast of Oahu, HI, USA, in 1972. The predicted genome size is 3,832,938 bp (G+C content, 60.03%), which contains 3,524 predicted coding sequences.
Complete Genome Sequence Of Staphylococcus Epidermidis Atcc 12228 Chromosome And Plasmids Generated By Long-Read Sequencing, Kyle S. Maclea, Ariel M. Trachtenberg
Complete Genome Sequence Of Staphylococcus Epidermidis Atcc 12228 Chromosome And Plasmids Generated By Long-Read Sequencing, Kyle S. Maclea, Ariel M. Trachtenberg
Life Sciences Faculty Scholarship
Staphylococcus epidermidis ATCC 12228 was sequenced using a long-read method to generate a complete genome sequence, including some plasmid sequences. Some differences from the previously generated short-read sequence of this nonpathogenic and non-biofilm-forming strain were noted. The assembly size was 2,570,371 bp with a total G+C% content of 32.08%.
Silver Oxide Coatings With High Silver-Ion Elution Rates And Characterization Of Bactericidal Activity., Sarah S Goderecci, Eric Kaiser, Michael Yanakas, Zachary Norris, Jeffrey Scaturro, Robert Oszust, Clarence D Medina, Fallon Waechter, Min Heon, Robert R Krchnavek, Lei Yu, Samuel E Lofland, Renee M Demarest, Gregory A Caputo, Jeffrey D Hettinger
Silver Oxide Coatings With High Silver-Ion Elution Rates And Characterization Of Bactericidal Activity., Sarah S Goderecci, Eric Kaiser, Michael Yanakas, Zachary Norris, Jeffrey Scaturro, Robert Oszust, Clarence D Medina, Fallon Waechter, Min Heon, Robert R Krchnavek, Lei Yu, Samuel E Lofland, Renee M Demarest, Gregory A Caputo, Jeffrey D Hettinger
College of Science & Mathematics Departmental Research
This paper reports the synthesis and characterization of silver oxide films for use as bactericidal coatings. Synthesis parameters, dissolution/elution rate, and bactericidal efficacy are reported. Synthesis conditions were developed to create AgO, Ag₂O, or mixtures of AgO and Ag₂O on surfaces by reactive magnetron sputtering. The coatings demonstrate strong adhesion to many substrate materials and impede the growth of all bacterial strains tested. The coatings are effective in killing Escherichia coli and Staphylococcus aureus, demonstrating a clear zone-of-inhibition against bacteria growing on solid media and the ability to rapidly inhibit bacterial growth in planktonic culture. Additionally, the coatings exhibit very …
Silver Oxide Coatings With High Silver-Ion Elution Rates And Characterization Of Bactericidal Activity., Sarah S Goderecci, Eric Kaiser, Michael Yanakas, Zachary Norris, Jeffrey Scaturro, Robert Oszust, Clarence D Medina, Fallon Waechter, Min Heon, Robert R Krchnavek, Lei Yu, Samuel E Lofland, Renee M Demarest, Gregory A Caputo, Jeffrey D Hettinger
Silver Oxide Coatings With High Silver-Ion Elution Rates And Characterization Of Bactericidal Activity., Sarah S Goderecci, Eric Kaiser, Michael Yanakas, Zachary Norris, Jeffrey Scaturro, Robert Oszust, Clarence D Medina, Fallon Waechter, Min Heon, Robert R Krchnavek, Lei Yu, Samuel E Lofland, Renee M Demarest, Gregory A Caputo, Jeffrey D Hettinger
Rowan-Virtua School of Osteopathic Medicine Departmental Research
This paper reports the synthesis and characterization of silver oxide films for use as bactericidal coatings. Synthesis parameters, dissolution/elution rate, and bactericidal efficacy are reported. Synthesis conditions were developed to create AgO, Ag₂O, or mixtures of AgO and Ag₂O on surfaces by reactive magnetron sputtering. The coatings demonstrate strong adhesion to many substrate materials and impede the growth of all bacterial strains tested. The coatings are effective in killing Escherichia coli and Staphylococcus aureus, demonstrating a clear zone-of-inhibition against bacteria growing on solid media and the ability to rapidly inhibit bacterial growth in planktonic culture. Additionally, the coatings exhibit very …
Curriculum Subcommittee Agenda, September 7, 2017, Utah State University
Curriculum Subcommittee Agenda, September 7, 2017, Utah State University
Educational Policies Committee
Program Proposals
- Adding a school-based and community-based emphases to the Bachelor of Science degree in Agricultural Education
- Offering a Masters in Communication Sciences
- Offering an Interfaith Leadership Certificate of Proficiency
Semester Course Approval Reviews
Other
- Revised R401 Process and Timeline
- Syllabus Updates
- Curriculog Update
The Setonian, September 7, 2017, Seton Hall University
First Interspecific Genetic Linkage Map For Castanea Sativa X Castanea Crenata Revealed Qtls For Resistance To Phytophthora Cinnamomi, Carmen Santos, Charles Dana Nelson, Tetyana Zhebentyayeva, Helena Machado, José Gomes-Laranjo, Rita Lourenço Costa
First Interspecific Genetic Linkage Map For Castanea Sativa X Castanea Crenata Revealed Qtls For Resistance To Phytophthora Cinnamomi, Carmen Santos, Charles Dana Nelson, Tetyana Zhebentyayeva, Helena Machado, José Gomes-Laranjo, Rita Lourenço Costa
Forest Health Research and Education Center Faculty Publications
The Japanese chestnut (Castanea crenata) carries resistance to Phytophthora cinnamomi, the destructive and widespread oomycete causing ink disease. The European chestnut (Castanea sativa), carrying little to no disease resistance, is currently threatened by the presence of the oomycete pathogen in forests, orchards and nurseries. Determining the genetic basis of P. cinnamomi resistance, for further selection of molecular markers and candidate genes, is a prominent issue for implementation of marker assisted selection in the breeding programs for resistance. In this study, the first interspecific genetic linkage map of C. sativa x C. crenata …
The World Is Facing A Global Sand Crisis, Aurora Torres, Jianguo "Jack" Liu, Jodi Brandt, Kristen Lear
The World Is Facing A Global Sand Crisis, Aurora Torres, Jianguo "Jack" Liu, Jodi Brandt, Kristen Lear
Human-Environment Systems Research Center Faculty Publications and Presentations
When people picture sand spread across idyllic beaches and endless deserts, they understandably think of it as an infinite resource. But as we discuss in a just-published perspective in the journal Science, over-exploitation of global supplies of sand is damaging the environment, endangering communities, causing shortages and promoting violent conflict.
Maternal Hypothalamic-Pituitary-Adrenal Axis Response To Foraging Uncertainty: A Model Of Individual Vs. Social Allostasis And The "Superorganism Hypothesis", Jeremy D. Coplan, Nishant K. Gupta, Asif Karim, Anna Rozenboym, Eric L.P. Smith, John G. Kral, Leonard A. Rosenblum
Maternal Hypothalamic-Pituitary-Adrenal Axis Response To Foraging Uncertainty: A Model Of Individual Vs. Social Allostasis And The "Superorganism Hypothesis", Jeremy D. Coplan, Nishant K. Gupta, Asif Karim, Anna Rozenboym, Eric L.P. Smith, John G. Kral, Leonard A. Rosenblum
Publications and Research
Introduction: Food insecurity is a major global contributor to developmental origins of adult disease. The allostatic load of maternal food uncertainty from variable foraging demand (VFD) activates corticotropin-releasing factor (CRF) without eliciting hypothalamic-pituitary-adrenal (HPA) activation measured on a group level. Individual homeostatic adaptations of the HPA axis may subserve second-order homeostasis, a process we provisionally term “social allostasis.” We postulate that maternal food insecurity induces a “superorganism” state through coordination of individual HPA axis response.
Methods: Twenty-four socially-housed bonnet macaque maternal-infant dyads were exposed to 16 weeks of alternating two-week epochs of low or high foraging demand shown to compromise …
Educational Policies Committee Agenda, September 7, 2017, Utah State University
Educational Policies Committee Agenda, September 7, 2017, Utah State University
Educational Policies Committee
- Subcommittee Reports
- Curriculum Subcommittee
- Course Approvals
- Program Proposals
- Academic Standards Subcommittee
- General Education Subcommittee
Alumna Developed Research Skills In Science Labs At Gardner-Webb, Office Of University Communications
Alumna Developed Research Skills In Science Labs At Gardner-Webb, Office Of University Communications
Gardner-Webb NewsCenter Archive
As a student in the Department of Natural Sciences at Gardner-Webb University, Amber Bellamy ’09 appreciated the various ways her professors gave her glimpses of her future career. Each class included several hands-on activities that sharpened her research skills and prepared her for graduate school. An environmental science major with a minor in biology, Bellamy took advantage of every learning opportunity.
Intersex And Families: Supporting Family Members With Intersex Variations, Tiffany Jones
Intersex And Families: Supporting Family Members With Intersex Variations, Tiffany Jones
Journal of Family Strengths
People with intersex variations have congenital atypical sex characteristics (chromosomal, hormonal, and/or anatomical) and receive protection against discrimination in only three countries globally; these include Australia, where the case study on which this chapter centers was based. This article considers the complex dynamics of family for people with intersex variations from their own perspective, filling a significant gap in the existing literature on family strengths studies of intersex issues. It draws on data from an Australian survey of 272 people with intersex variations and specifically considers in detail for the first time questions on these participants’ family discussions of intersex …
Faculty Senate Chronicle For May 4, 2017, Jon Miller
Faculty Senate Chronicle For May 4, 2017, Jon Miller
The University of Akron Faculty Senate Chronicle
Minutes of the Faculty Senate meeting of May 2017.
Urban Impacts To Forest Productivity, Soil Quality, And Canopy Structure In Forest Park, Portland, Oregon, Andrew David Addessi
Urban Impacts To Forest Productivity, Soil Quality, And Canopy Structure In Forest Park, Portland, Oregon, Andrew David Addessi
Dissertations and Theses
Land use practices and exposure to low impact disturbances associated with an urban environment can alter forest structure and function. Past and ongoing research in Forest Park, a large urban forest in Portland, Oregon, suggests that mature mixed Douglas-fir (Psuedotsuga meziesii)-hardwood stands in the more urban end of the park lack a shade-tolerant conifer understory composed of the late successional conifer tree species, such western hemlock (Tsuga heterophylla) and western red-cedar (Thuja plicata). 5-year plot remeasurement data that characterizes productivity and mortality patterns did not show a strong relationship to urban proximity. Plot productivity …
Stability At Low Densities Or Endangered? Spatiotemporal Population Dynamics Of The Caddo Madtom (Noturus Taylori), Brittany Latrice Mccall
Stability At Low Densities Or Endangered? Spatiotemporal Population Dynamics Of The Caddo Madtom (Noturus Taylori), Brittany Latrice Mccall
Student Theses and Dissertations
Imperilment in North American freshwater fishes is primarily due to habitat alteration, deterioration, and fragmentation. In response to the aquatic biodiversity crisis, there has been a call for action by the Center for Biological Diversity, with a petition for the federal listing of 404 aquatic species in the southeastern U.S. This thesis focuses on a petitioned species, the Caddo Madtom, Noturus taylori. The chapters in this thesis address the genetic variation, habitat limitations, and status of the Arkansas endemic. In summation, N. taylori was found to have a high level of genetic variation for an endemic madtom, and is relatively …
Hawks' Herald -- Sep. 7, 2017, Roger Williams University
Hawks' Herald -- Sep. 7, 2017, Roger Williams University
Hawk's Herald
No abstract provided.
A Pilot Clinical Trial Of Recombinant Human Angiotensin-Converting Enzyme 2 In Acute Respiratory Distress Syndrome., Akram Khan, Cody Benthin, Brian Zeno, Timothy E Albertson, John Boyd, Jason D Christie, Richard Hall, Germain Poirier, Juan J Ronco, Mark Tidswell, Kelly Hardes, William M Powley, Tracey J Wright, Sarah K Siederer, David A Fairman, David A Lipson, Andrew I Bayliffe, Aili L Lazaar
A Pilot Clinical Trial Of Recombinant Human Angiotensin-Converting Enzyme 2 In Acute Respiratory Distress Syndrome., Akram Khan, Cody Benthin, Brian Zeno, Timothy E Albertson, John Boyd, Jason D Christie, Richard Hall, Germain Poirier, Juan J Ronco, Mark Tidswell, Kelly Hardes, William M Powley, Tracey J Wright, Sarah K Siederer, David A Fairman, David A Lipson, Andrew I Bayliffe, Aili L Lazaar
Trauma and Acute Care Articles
BACKGROUND: Renin-angiotensin system (RAS) signaling and angiotensin-converting enzyme 2 (ACE2) have been implicated in the pathogenesis of acute respiratory distress syndrome (ARDS). We postulated that repleting ACE2 using GSK2586881, a recombinant form of human angiotensin-converting enzyme 2 (rhACE2), could attenuate acute lung injury.
METHODS: We conducted a two-part phase II trial comprising an open-label intrapatient dose escalation and a randomized, double-blind, placebo-controlled phase in ten intensive care units in North America. Patients were between the ages of 18 and 80 years, had an American-European Consensus Criteria consensus diagnosis of ARDS, and had been mechanically ventilated for less than 72 h. …