Digital Commons Network^™

The Ongoing Quest For The Holy Bone Graft Grail: Scientific Progress, Economic Bonanza, Or Quixotic Quagmire?, Jens R Chapman, Karsten Wiechert, Jeffrey C Wang

Articles, Abstracts, and Reports

No abstract provided.

Sustainable Solutions

Sustainable Solutions Newsletter (2016-2021)

• Director's Message
• Campus Opportunities
• 3rd Annual Pallet Challenge
• Sustainability Seminar: Dr. Vandana Shiva
• Apartment Gardening 101 Workshop
• After School Garden Program
• Green Ambassadors- a Green Student Organization
• Tailgate Game- day Recycling
• Bee-Well Workshop
• Environmental Community Cinema: Life Off Grid
• Residence Hall Recycling Incentive Program
• Individual Student and Organization Mini-Grants
• Adopt-A-Stream volunteers needed
• NC's Vermiculture Conference

Learning Opportunities 2017/2018, Illinois Mathematics And Science Academy

Course Catalogs

The graduation requirements of the Illinois Mathematics and Science Academy are in concert with those maintained by the State of Illinois with additional requirements as established by the IMSA Board of Trustees. Each semester students must take a minimum of five courses (2.5 credits) for a letter grade (not Pass/Fail) not including Fine Arts, Wellness, and Independent Study courses. Only courses taken for a letter grade will count towards graduation credit.

Assessing The Openness Of Anthropology Journals, Melody Dale, Nickoal Eichmann-Kalwara, Sheeji Kathuria, Mary Ann Jones

UL Publications

This study analyzes the extent of gold open access (OA) publishing options in 377 anthropology journals by applying a coding scheme ranging from 0) non-transparent publishing options to 5) fully OA (free to read and publish without embargo). This analysis is meant to simplify the process of identifying OA journal publishing options in the discipline of anthropology, in addition to sharing findings on some of the prominent issues in OA publishing as they relate to anthropology journals, including non-transparency by publishers and the prevalence and price of article processing charges (APCs). We conclude that publishers should be more transparent about …

Self-Compassion, Self-Injury, And Pain, Wesley Ellen Gregory, Jillian V. Glazer, Kathy R. Berenson

Psychology Faculty Publications

We conducted an experiment to examine self-compassion and responses to pain among undergraduate women with and without histories of self-injury. After a writing task that has been shown to increase self-compassion in a values-affirming condition relative to a neutral control condition, participants completed a self-report measure of state self-compassion and the cold pressor task. As predicted, participants with a history of self-injury reported lower trait self-compassion than those without such a history, and participants in the values-affirming condition reported significantly higher state self-compassion than those in the control condition. Moreover, participants with a history of self-injury demonstrated significantly less insensitivity …

Ribonucleoprotein Purification And Characterization Using Rna Mango, Shanker Shyam S. Panchapakesan, Matthew L. Ferguson, Eric J. Hayden, Xin Chen, Aaron A. Hoskins, Peter J. Unrau

Physics Faculty Publications and Presentations

The characterization of RNA–protein complexes (RNPs) is a difficult but increasingly important problem in modern biology. By combining the compact RNA Mango aptamer with a fluorogenic thiazole orange desthiobiotin (TO1-Dtb or TO3-Dtb) ligand, we have created an RNA tagging system that simplifies the purification and subsequent characterization of endogenous RNPs. Mango-tagged RNP complexes can be immobilized on a streptavidin solid support and recovered in their native state by the addition of free biotin. Furthermore, Mango-based RNP purification can be adapted to different scales of RNP isolation ranging from pull-down assays to the isolation of large amounts of biochemically defined cellular …

Introduction To U.S. Export Controls For The Commercial Space Industry, U.S. Department Of Commerce’S Office Of Space Commerce, Federal Aviation Administration’S Office Of Commercial Space Transportation

Space Law Documents

This guidebook provides basic information to help commercial space organizations, especially emerging entrepreneurial firms, considering business in the international market. It is intended to serve as a starting point in the preparation for the export control process. This is an update to the 2008 edition and reflects changes due to the Export Control Reform initiative. Because most space technologies are subject to export controls, it is your responsibility to be aware of the steps necessary to ensure that your operations are lawful. While this guidebook gives an overview of the general responsibilities and procedures, it cannot replace a full understanding …

Water Current, Volume 49, No. 4, Fall 2017

Water Current Newsletter

2018 Water Tour Heads West to Wyoming

Spring water seminar lectures will Key on “Advances in Irrigation Management”

Field Evidence Challenges The Often-Presumed Relationship Between Early Male Maturation And Female-Biased Sexual Size Dimorphism, Marie Claire Chelini, Eileen Hebets

Eileen Hebets Publications

Female-biased sexual size dimorphism (SSD) is often considered an epiphenomenon of selection for the increased mating opportunities provided by early male maturation (i.e., protandry). Empirical evidence of the adaptive significance of protandry remains nonetheless fairly scarce. We use field data collected throughout the reproductive season of an SSD crab spider, Mecaphesa celer, to test two hypotheses: Protandry provides fitness benefits to males, leading to female-biased SSD, or protandry is an indirect consequence of selection for small male size/large female size. Using field-collected data, we modeled the probability of mating success for females and males according to their timing of …

Speaking Of Genocide: Double Binds And Political Discourse, Benjamin Meiches

Genocide Studies and Prevention: An International Journal

Genocide scholars have always argued over the best definition of genocide. However, recent genocide studies have begun to emphasize both the ‘contestable’ nature of genocide and, paradoxically, call for clear or rigid definitions of the term. This article evaluates this tension by examining the act of defining genocide as a type of epistemological practice. Placing the act of definition in the context of a complex socio-linguistic system, the article shows how genocide discourse is subject to a variety of demands and pressures. These pressures, internal to genocide discourse, inadvertently promote restrictive and paradoxical formulations of the concept. To illustrate this …

Editors' Introduction, Christian Gudehus, Susan Braden, Douglas Irvin-Erickson

Genocide Studies and Prevention: An International Journal

No abstract provided.

Resveratrol Increases Cathelicidin Expression And Offers A Novel Approach To Combat Staph Aureus Invasion., Shivtaj Mann Do, Kyle Kreitman Do

Department of Medicine

No abstract provided.

Photosensing And Thermosensing By Phytochrome B Require Both Proximal And Distal Allosteric Features Within The Dimeric Photoreceptor, E Sethe Burgie, Adam N. Bussell, Shu-Hui Lye, Tong Wang, Weiming Hu, Katrice E. Mcloughlin, Erin L. Weber, Huilin Li, Richard D. Vierstra

Biology Faculty Research

Phytochromes (Phys) encompass a diverse collection of bilin-containing photoreceptors that help plants and microorganisms perceive light through photointerconversion between red light (Pr) and far-red light (Pfr)-absorbing states. In addition, Pfr reverts thermally back to Pr via a highly enthalpic process that enables temperature sensation in plants and possibly other organisms. Through domain analysis of the Arabidopsis PhyB isoform assembled recombinantly, coupled with measurements of solution size, photoconversion, and thermal reversion, we identified both proximal and distal features that influence all three metrics. Included are the downstream C-terminal histidine kinase-related domain known to promote dimerization and a conserved patch just upstream …

Characterization Of Atrial Fibrillation Adverse Events Reported In Ibrutinib Randomized Controlled Registration Trials, Jr Brown, J Moslehi, S O’Brien, P Ghia, Et Al

Peninsula Medical School

The first-in-class Bruton's tyrosine kinase inhibitor ibrutinib has proven clinical benefit in B-cell malignancies; however, atrial fibrillation (AF) has been reported in 6-16% of ibrutinib patients. We pooled data from 1505 chronic lymphocytic leukemia and mantle cell lymphoma patients enrolled in four large, randomized, controlled studies to characterize AF with ibrutinib and its management. AF incidence was 6.5% [95% Confidence Interval (CI): 4.8, 8.5] for ibrutinib at 16.6-months versus 1.6% (95%CI: 0.8, 2.8) for comparator and 10.4% (95%CI: 8.4, 12.9) at the 36-month follow up; estimated cumulative incidence: 13.8% (95%CI: 11.2, 16.8). Ibrutinib treatment, prior history of AF and age …

The Prospects Of Zinc As A Structural Material For Biodegradable Implants—A Review Paper, Galit Katarivas Levy, Jeremy Goldman, Eli Aghion

Michigan Tech Publications, Part 1

In the last decade, iron and magnesium, both pure and alloyed, have been extensively studied as potential biodegradable metals for medical applications. However, broad experience with these material systems has uncovered critical limitations in terms of their suitability for clinical applications. Recently, zinc and zinc-based alloys have been proposed as new additions to the list of degradable metals and as promising alternatives to magnesium and iron. The main byproduct of zinc metal corrosion, Zn²⁺, is highly regulated within physiological systems and plays a critical role in numerous fundamental cellular processes. Zn²⁺ released from an implant may suppress …

Sustainable Solutions, Georgia Southern University

Sustainable Solutions Newsletter (2016-2021)

• Campus Opportunities
• GreenFest
• 3rd Annual Pallet Challenge
• Sustainability Seminar: Dr. Vandana Shiva
• Environmental Community Cinema Presents: The True Cost
• Sustainability Social
• Georgia Southern Sustainability Network Annual Conference
• After School Garden Program
• Green Ambassadors- a Green Student Organization
• Tailgate Game-day Recycling
• Residence Hall Recycling Incentive Program
• Campus in the Spotlight
• Lunch and Learn with the Botanic Garden at Georgia Southern
• Adopt-A-Stream volunteers needed
• Georgia Conservancy: Sapelo Island Service Weekend
• Georgia Conservancy: Yellow River & Paddle Jame
• Forest Therapy Retreat
• Conferences
• EPA: Campus RainWorks Challenge
• Sustainability related Study Abroad
• Webinars
• Jobs/Internships
• FIRST Green Carpet Fashion Awards, Italia
• Green Tip

A Conceptual Model To Identify Intent To Use Chemical-Biological Weapons, Mary D. Zalesny, Paul Whitney, Amanda White, Theodore R. Plasse, Michael T. Grundy

Journal of Strategic Security

This paper describes a conceptual model to identify and interrelate indicators of intent of non-state actors to use chemical or biological weapons. The model expands on earlier efforts to understand intent to use weapons of mass destruction by building upon well-researched theories of intent and behavior and focusing on a sub-set of weapons of mass destruction (WMD) to account for the distinct challenges of employing different types of WMD in violent acts. The conceptual model is presented as a first, critical step in developing a computational model for assessing the potential for groups to use chemical or biological weapons.

Assessment Of Intra And Interregional Genetic Variation In The Eastern Red-Backed Salamander, Plethodon Cinereus, Via Analysis Of Novel Microsatellite Markers, Alexander C. Cameron, Jeffry J. Anderson, Robert B. Page

Biology Faculty Publications (Archived)

The red-backed salamander (Plethodon cinereus) has long-served as a model system in ecology, evolution, and behavior, and studies surveying molecular variation in this species have become increasingly common over the past decade. However, difficulties are commonly encountered when extending microsatellite markers to populations that are unstudied from a genetic perspective due to high levels of genetic differentiation across this species’ range. To ameliorate this issue, we used 454 pyrosequencing to identify hundreds of microsatellite loci. We then screened 40 of our top candidate loci in populations in Virginia, Pennsylvania, and Ohio—including an isolated island population ~ 4.5 km off the …

Effect Of Exercise Intervention On Flow-Mediated Dilation In Overweight And Obese Adults: Meta-Analysis, Younsun Son, Kyungun Kim, Soeun Jeon, Minsoo Kang, Sukho Lee, Yoonjung Park

Kinesiology Faculty Publications (Archived)

The objective of this meta-analysis is to summarize the effect of exercise intervention on flow-mediated dilatation (FMD) in overweight and obese adults. We searched four electronic databases (PubMed/Medline, Scopus, and CINAHL) through June 2016 for relevant studies pertaining to the effectiveness of exercise intervention on FMD. Seventeen of the 91 studies identified met the inclusion criteria. Comprehensive Meta-Analysis software (version 3) was used to compute the standardized mean difference effect size (ES) and 95% CI using a random effects model. We calculated 34 ESs. We found that exercise intervention had medium and positive effects on FMD, with an overall ES …

Artemis: Depictions Of Form And Femininity In Sculpture, Laura G. Waters

Student Publications

Grecian sculpture has been the subject of investigation for centuries. More recently, however, emphasis in the field of Art History on the politics of gender and sexuality portrayal have opened new avenues for investigation of those old statues. In depicting gender, Ancient Greek statuary can veer towards the non-binary, with the most striking examples being works depicting Hermaphroditos and ‘his’ bodily form. Yet even within the binary, there are complications. Depictions of the goddess Artemis are chief among these complications of the binary, with even more contradiction, subtext, and varied interpretation than representations of Amazons. The numerous ways Artemis has …

Teaching With Big Data: Report From The 2016 Society For Neuroscience Teaching Workshop, William Grisham, Joshua C. Brumberg, Terri Gilbert, Linda Lanyon, Robert W. Williams, Richard F. Olivo

Neuroscience: Faculty Publications

As part of a series of workshops on teaching neuroscience at the Society for Neuroscience annual meetings, William Grisham and Richard Olivo organized the 2016 workshop on "Teaching Neuroscience with Big Data." This article presents a summary of that workshop.

Speakers provided overviews of open datasets that could be used in teaching undergraduate courses. These included resources that already appear in educational settings, including the Allen Brain Atlas (presented by Joshua Brumberg and Terri Gilbert), and the Mouse Brain Library and GeneNetwork (presented by Robert Williams). Other resources, such as NeuroData (presented by William R. Gray Roncal), and OpenFMRI, NeuroVault, …

Gpr37l1 Modulates Seizure Susceptibility: Evidence From Mouse Studies And Analyses Of A Human Gpr37l1 Variant, Michelle M. Giddens, Jennifer C. Wong, Jason P. Schroeder, Emily G. Farrow, Brilee M. Smith, Sharon Owino, Sarah E. Soden, Rebecca C. Meyer, Carol Saunders, J. B. Lepichon, David Weinshenker, Andrew Escayg, Randy A. Hall

Neuroscience: Faculty Publications

Progressive myoclonus epilepsies (PMEs) are disorders characterized by myoclonic and generalized seizures with progressive neurological deterioration. While several genetic causes for PMEs have been identified, the underlying causes remain unknown for a substantial portion of cases. Here we describe several affected individuals from a large, consanguineous family presenting with a novel PME in which symptoms begin in adolescence and result in death by early adulthood. Whole exome analyses revealed that affected individuals have a homozygous variant in GPR37L1 (c.1047G > T [Lys349Asn]), an orphan G protein-coupled receptor (GPCR) expressed predominantly in the brain. In vitro studies demonstrated that the K349N substitution …

Factors Driving Demography And Temporal Variability In Ph Of The Acid Weed, Desmarestia Herbacea, Angela T. Zepp

Capstone Projects and Master's Theses

Demographic studies allow for a better understanding of how populations change over time and establish a baseline to examine how biotic and abiotic factors influence populations. The annual alga Desmarestia herbacea, or the acid weed, accumulates sulfuric acid within cell vacuoles, likely as a chemical defense mechanism. Whether intracellular pH varies among different life history stages is poorly understood. A D. herbacea population in the Stillwater Cove, California kelp bed was assessed for two years in order to measure how internal pH varies relative to demographics, season, grazing pressure and oceanography. The timing of both spring recruitment and fall …

Physical Factors Influencing Phytoplankton Abundance In Southern Monterey Bay, C. Ryan Manzer

Capstone Projects and Master's Theses

As the base of almost all marine food webs, phytoplankton play a dominant role in determining the productivity of marine ecosystems. Recent studies have highlighted the dynamic variability of phytoplankton abundance in nearshore ecosystems over synoptic time scales. The inability of satellite ocean color monitoring to resolve chlorophyll values at a resolution less than 1 km and a reliable temporal resolution of ~8 days means this data cannot adequately capture the impact of nearshore dynamics on chlorophyll abundance and distribution. Therefore, a greater understanding of the physical mechanisms that contribute to this variability is required to assess impacts of current …

Gametophyte Fitness And Costs Of Self-Fertilization In The Giant Kelp Macrocystis Pyrifera, Robert A. San Miguel

Capstone Projects and Master's Theses

It is widely established that inbreeding can incur heavy costs in a variety of plants, animals, and algae. To date, ten species of kelp have been tested to ascertain the degree to which selfing reduces recruitment of juvenile sporophytes and of those ten species, seven have reduced recruitment when inbred. In this study, I set out to understand whether there is variability in response to self-fertilization among giant kelp gametophytes grown from multiple sites, what those differences are, and how it affects sporophyte recruitment. I collected reproductive sporophylls from fifteen Macrocystis pyrifera individuals in Point Loma, Leo Carrillo State Beach, …

Framework For Integration Of Data From Remotely Operated Cameras Into Recreational Fishery Assessments In Western Australia, Aldo S. Steffe, S.M Taylor, Stuart Blight, Karina L. Ryan, Cameron J. Desfosses, Alissa Tate, Claire B. Smallwood, Eva K. Lai, Fabian I. Trinnie, Brent S. Wise

Fisheries Research Reports

Remotely operated cameras can be used for cost-efficient monitoring of recreational fishing activities. This report provides an overview of the current usage of cameras in recreational fishery assessments by the Department of Primary Industries and Regional Development. Since 2006, 32 remotely operated cameras have been installed at 26 locations throughout Western Australia and currently 28 cameras are in use.

Intentional Supervision: Developing Ethical Decisional Making, Lisa S. Sosin, John Jonathan Suroshan Harrichand, Patricia Kimball, Lucy C. Phillips

Faculty Publications and Presentations

No abstract provided.

Much Ado About The Tpp's Effect On Pharmaceuticals, Emily Michiko Morris

Faculty Scholarly Works

The many provisions in the Trans-Pacific Partnership Agreement (TPP) that were beneficial to the pharmaceutical industry caused a good deal of controversy. Specifically, critics alleged that the TPP's provisions requiring that member states expand patentable subject matter and adjust pharmaceutical patent terms would have raised drug prices and hindered access to medicines, particularly in developing countries. But closer examination of these provisions, as well as the various ways in which member states can modify or ameliorate the effects of these provisions, suggests that their potential effect on drug prices and access to health care is not nearly so clear.

Psychosocial Functioning And The Cortisol Awakening Response: Meta-Analysis, P-Curve Analysis, And Evaluation Of The Evidential Value In Existing Studies, Ian Andres Boggero, Camelia E. Hostinar, Eric A. Haak, Michael L. M. Murphy, Suzanne C. Segerstrom

Psychology Faculty Publications

Cortisol levels rise immediately after awakening and peak approximately 30-45 minutes thereafter. Psychosocial functioning influences this cortisol awakening response (CAR), but there is considerable heterogeneity in the literature. The current study used p-curve and metaanalysis on 709 findings from 212 studies to test the evidential value and estimate effect sizes of four sets of findings: those associating worse psychosocial functioning with higher or lower cortisol increase relative to the waking period (CARi) and to the output of the waking period (AUCw). All four sets of findings demonstrated evidential value. Psychosocial predictors explained 1%-3.6% of variance in CARi and AUCw …

Report Of The Ishlt Working Group On Primary Lung Graft Dysfunction Part Iii: Mechanisms: A 2016 Consensus Group Statement Of The International Society For Heart And Lung Transplantation, Andrew E. Gelman, Andrew J. Fisher, Howard J. Huang, Maher A. Baz, Ciara M. Shaver, Thomas M. Egan, Micheal S. Mulligan

Surgery Faculty Publications

No abstract provided.