Digital Commons Network^™

Diapause Dynamics And Host Plant Utilization Of Colias Philodice, Colias Interior And Their Hybrids (Lepidoptera: Pieridae), David N. Karowe

The Great Lakes Entomologist

Abnormal diapause dynamics and, to a lesser extent, reduced efficiency of host utilization by hybrid larvae constitute potential post-zygotic barriers to gene flow between a multivoltine legume-feeder, Colias philodice (Lepidoptera: Pieridae) and a univoltine Vaccinium-feeder, C. interior. At the time when C. interior larvae enter diapause, approximately 50% of hybrid larvae ceased feeding but did not enter diapause, and subsequently starved. Hybrid larvae readily accepted the host plants of both parental species. However, relative to C. philodice, hybrid larvae displayed a significantly reduced fifth instar relative growth rate (RGR) when fed the primary legume host, Medicago sativa. …

“These Classes Have Been My Happy Place”: Feasibility Study Of A Self-Care Program In Native Hawaiian Custodial Grandparents, Loriena Yancura, Heather Greenwood-Junkermeier, Christine A. Fruhauf

Asian/Pacific Island Nursing Journal

Native Hawaiian custodial grandparents have a distinctive set of strengths and challenges that may lead them to benefit from a structured self-care program. The purpose of this paper is to describe a feasibility study with nine Native Hawaiian custodial grandparents who participated in a 6-week self-care intervention. Based on open-ended questions during the post-questionnaire and at the 6-month follow-up focus group, grandparent participants noted that their grandchildren needed education and clothing. Most grandparents did not endorse statements that their grandchildren had any mental or physical health conditions. Grandparents reflected that the intervention provided them with skills to help cope with …

Under Surveillance: Interrogating Linguistic Policing In Black Girlhood, Pamela Jones

Occasional Paper Series

Abstract

The youngest of Black girls are scrutinized for their language choices and surveilled on the basis of their ability to shift out of their vernacular and into Standard English (SE). In this essay, I revisit my own Black girlhood (Brown, 2013) to interrogate how those in schooled contexts compelled me to deny the “skin that (I) speak” (Delpit, 2002, p. xvii). Using intersectionality as my theoretical frame (Collins, 2000), I arrive at new understandings about resisting multiple oppressions and consider possible interventions at the school level.

Keywords: Black girlhood, intersectionality, African-American Language (AAL), identity, code-meshing.

Effects Of Probiotics On The Aquaculture Performance Of Cobia (Rachycentron Canadum) And Yellowfin Tuna (Thunnus Albacares), Juan Felipe Sierra De La Rosa

Open Access Dissertations

Effects of probiotics pulse-supplementation on cobia were assessed over two experimental trials carried out with larval and juvenile stages using a commercial blend of Bacillus subtilis, B. lincheniformis, B. magaterium, and Brevibacillus laterosporus. The first trial evaluated the effects of probiotic-enriched live feeds (7x106 and 10x106 colony-forming units (CFU) L-1 for rotifers and Artemia sp., respectively) on the growth and survival of fingerlings during a commercial larval rearing run. The second trial assessed the effects of probiotics supplementation in dry feeds (109 CFU kg-1) on the survival, growth, feed conversion ratio (FCR), ammonia excretion of cobia juveniles (58 g to …

Wildlife Policy And Conservation: An Interdisciplinary Historical Perspective, Catherine C. Macdonald

Open Access Dissertations

It is widely recognized that historical data about human interactions with the natural world is critical to understanding anthropogenic environmental change over time (McNeill, 2001). However, the potential contribution of interdisciplinary historical perspectives to wildlife conservation problems remains largely unexplored. Human-wildlife interactions are informed by a variety of factors, including the scientific and ecological literacy of human populations, human values, the availability of habitat and resources for human and animal populations, and the types of resource conflicts taking place (or likely to take place) (Treves et al., 2006). The role of historical interactions in shaping present attitudes and conflicts can …

Mitochondrial Dynamics And Respiration Within Cells With Increased Open Pore Cytoskeletal Meshes, David H. Jang, Sarah C. Seeger, Martha E. Grady, Frances S. Shofer, David M. Eckmann

Mechanical Engineering Faculty Publications

The cytoskeletal architecture directly affects the morphology, motility, and tensional homeostasis of the cell. In addition, the cytoskeleton is important for mitosis, intracellular traffic, organelle motility, and even cellular respiration. The organelle responsible for a majority of the energy conversion for the cell, the mitochondrion, has a dependence on the cytoskeleton for mobility and function. In previous studies, we established that cytoskeletal inhibitors altered the movement of the mitochondria, their morphology, and their respiration in human dermal fibroblasts. Here, we use this protocol to investigate applicability of power law diffusion to describe mitochondrial locomotion, assessment of rates of fission and …

Metabolic Dysregulation And Cancer Mortality In A National Cohort Of Blacks And Whites, Tomi Akinyemiju, Justin Xavier Moore, Suzanne Judd, Susan Lakoski, Michael Goodman, Monika M. Safford, Maria Pisu

Epidemiology and Environmental Health Faculty Publications

Background: We examined the association between metabolic dysregulation and cancer mortality in a prospective cohort of Black and White adults.

Methods: A total of 25,038 Black and White adults were included in the analysis. Metabolic dysregulation was defined in two ways: 1) using the joint harmonized criteria for metabolic syndrome (MetS) and 2) based on factor analysis of 15 variables characterizing metabolic dysregulation. We estimated hazards ratios (HRs) and 95% confidence intervals (CIs) for the association of MetS and metabolic dysregulation with cancer mortality during follow-up using Cox proportional hazards models.

Results: About 46% of Black and 39% of White …

9-Aminoacridine Inhibits Ribosome Biogenesis And Synergizes With Cytotoxic Drugs To Induce Selective Killing Of P53-Deficient Cells, Leonid Anikin, Dimitri G Pestov

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Common cancer treatments target rapidly dividing cells and do not discriminate between cancer and normal host cells. One approach to mitigating negative side‐effects of cancer treatment is to temporarily arrest cell cycle progression and thus protect normal cells during cytotoxic treatments, a concept called cyclotherapy. We recently proposed that transient inhibition of post‐transcriptional steps of ribosome biogenesis (RBG) can be used to selectively arrest p53‐positive host cells and not p53‐null cancer cells. In this study, we investigated whether cytoprotective RBG inhibition can be achieved through small molecule treatment.

Modification Of The Ribosome As Part Of The Adaptive Response To Oxidative Stress In Yeast, Jessica A Zinskie, Daniel Shedlovskiy, Ethan Gardner, Dimitri G Pestov, Natalia Shcherbik

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Living organisms are constantly exposed to a variety of environmental and internal stressors tha tare detrimental to their cellular physiology and viability. One such condition, oxidativestress, is caused by abnormal amounts of Reactive Oxygen Species (ROS) that can lead to damage to proteins, nucleic acids, and lipids. Although the mechanisms to neutralize ROS have been widely studied, the understanding of ROS‐mediated signaling for these mechanisms is rather incomplete and sparse. We have uncovered a previously undescribed phenomenon of yeast ribosomes to respond to elevated levels of ROS through a specific endonucleolytic cleavage of the 25S rRNA in the c‐loop of …

“My Two Years With Jesse Jackson Sr”, Part 2, Preston Love Jr.

Black Studies Faculty Publications

“My Two Years with Jesse Jackson Sr”- Part 2 (Reflections of my time with America’s second African-American candidate for his party’s nomination for President -1984)

With the recent announcement that Rev. Jackson has Parkinson’s disease I thought Omaha Star readers would enjoy some of my reflections from the historical times I spent with this civil rights icon. Part 1 (The Prelude), is recommended reading)

Invited Article: Bridging The Gap – Supporting The Transition From High School To College, Julie A. Frischmann, Kelly S. Moor

Administrative Issues Journal

Idaho State University’s Bengal Bridge is a summer program designed to help students successfully transition from high school to their first year of college at Idaho State University. All Bridge students at ISU take two general education courses, plus an additional credit of supplemental instruction focused on academic strategies specific to the disciplines represented by those general education courses, as well as a First Year Transition (ACAD) course to facilitate engagement with and acculturation to the university community—a total of nine to 10 credits in just seven weeks. Bridge students are also supported by one-to-one academic coaching, supplemental tutoring, peer …

Understanding Huntington's Disease Using Machine Learning Approaches, Sonali Lokhande

KGI Theses and Dissertations

Huntington’s disease (HD) is a debilitating neurodegenerative disorder with a complex pathophysiology. Despite extensive studies to study the disease, the sequence of events through which mutant Huntingtin (mHtt) protein executes its action still remains elusive. The phenotype of HD is an outcome of numerous processes initiated by the mHtt protein along with other proteins that act as either suppressors or enhancers of the effects of mHtt protein and PolyQ aggregates. Utilizing an integrative systems biology approach, I construct and analyze a Huntington’s disease integrome using human orthologs of protein interactors of wild type and mHtt protein. Analysis of this integrome …

Foraging Behavior And Energetics Of Albatrosses In Contrasting Breeding Environments, Michelle Antolos, Scott Shaffer, Henri Weimerskirch, Yann Tremblay, Daniel Costa

Faculty Publications, Biological Sciences

Animals can maximize fitness by optimizing energy acquisition through the selection of favorable foraging habitats, but trade-offs exist between time spent in preferred feeding habitats, energetic costs of travel, and reproductive constraints. For pelagic seabirds, geographic distribution of suitable breeding islands can restrict access to marine prey resources and influence foraging strategies. Laysan (Phoebastria immutabilis) and black-footed albatrosses (P. nigripes) breeding in the Northwest Hawaiian Islands, and Indian yellow-nosed albatrosses (Thalassarche carteri) breeding in the Southern Indian Ocean, utilize productive subtropical-subpolar transition zones during their breeding and non-breeding periods, but this marine feature is at a comparatively greater distance for …

This Is Herpes: A Qualitative Investigation Of The Disclosure Patterns Of Hsv2 Individuals, Katrina Miles

Masters Theses, 2010-2019

It is estimated that by 2025, 49% of the female population and 39% of the male population, aged 15-39, will have contracted herpes simplex virus 2, or as it is more commonly known, genital herpes (Fisman, Lipsitch, Hook & Goldie, 2002). However, little is understood about the ways that those with genital herpes communicate their condition with potential partners, friends, or family members. Using in-depth qualitative interviews this research focuses on understanding the unique patterns that individuals with genital herpes engage to disclose their status to significant others. Utilizing the theories of Communication Privacy Management and the Disclosure Decision-Making Model …

Targeting Ribosome Assembly Factors Selectively Protects P53 Positive Cells From Chemotherapeutic Agents, Russell T. Sapio, Anastasiya Nezdyur, Matthew Krevetski, Leonid Anikin, Vincent J. Manna, N. Minkovsky, Dimitri G Pestov

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Many chemotherapeutic agents act in a nondiscriminatory fashion, targeting both cancerous and noncancerous cells in Sphase and Mphase. One approach to reduce the toxic side effects in normal tissue is to exploit the differences in p53 functionality between cancerous and noncancerous cells. For example, activating p53 signaling by nongenotoxic means can transiently arrest noncancerous p53 positive cells in G1 phase and protect them from the cytotoxic effects of chemotherapeutic drugs. However, since most cancerous cells have faulty p53 signaling, they will proceed to cycle, and continue to be affected by the drug. In this study we asked if this G1‐phase …

Fall Commencement Program, December 15, 2017, Coastal Carolina University

Commencement Programs

Program of Commencement Exercises at Coastal Carolina University.

The Role Of Mapk And Scf In The Destruction Of Med13 In Cyclin C Mediated Cell Death, David C Stieg, Stephen D Willis, Joseph Scuorzo, Mia Song, Vidyaramanan Ganesan, Randy Strich, Katrina F Cooper

Rowan-Virtua School of Osteopathic Medicine Departmental Research

In response to stress, the yeast¹ and mammalian² cyclin C translocate from the nucleus to the cytoplasm, where it associates with the GTPase Drp1/Dnm1 to drive mitochondrial fragmentation and apoptosis. Therefore, the decision to release cyclin C represents a key life or death decision. In unstressed cells, the cyclin C‐Cdk8 kinase regulates transcription by associating with the Mediator of RNA polymerase II. We previously reported that the Mediator component Med13 anchors cyclin C in the nucleus³. Loss of Med13 function leads to constitutive cytoplasmic localization of cyclin C, resulting in fragmented mitochondria, hypersensitivity to stress and …

Snf1 Dependent Destruction Of Med13 Is Required For Programmed Cell Death Following Oxidative Stress In Yeast, Stephen D Willis, David C Stieg, R. Shah, Randy Strich, Katrina F Cooper

Rowan-Virtua School of Osteopathic Medicine Departmental Research

All eukaryotic cells, when faced with unfavorable environmental conditions, have to decide whether to mount a survival or cell death response. The conserved cyclin C and its kinase partner Cdk8 play a key role in this decision. Both are members of the Cdk8 kinase module that, along with Med12 and Med13, associate with the core mediator complex of RNA polymerase II. In S. cerevisiae, oxidative stress triggers Med13 destruction¹, which thereafter releases cyclin Ci nto the cytoplasm. Cytoplasmic cyclin C associates with mitochondria where it induces hyper-fragmentation and programmed cell death². This suggests a model in …

Developmental Evaluation: Complexity Leadership Theory In Practice-A Mixed Methods Study, Terrence S. Fernsler

Dissertations, 2014-2019

Networks of organizations frequently operate within complex adaptive systems in which leadership is practiced in uncertain and ambiguous conditions. Background in complexity theories is first provided, along with how they apply to organizations operating in complex adaptive systems. A theory—Complexity Leadership Theory (CLT)—has been derived to model leadership in complex adaptive systems; CLT has been tested very little in practice. Developmental Evaluation (DE) is a practice which helps organizations and their networks adapt within complex adaptive systems. Since both processes are based in complexity, leadership characteristics in each can be expected to be similar.

This exploratory mixed methods study incorporates …

Translocation Of Cyclin C During Oxidative Stress Is Regulated By Interactions With Multiple Trafficking Proteins, Daniel G J Smethurst, Katrina F Cooper, Randy Strich

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Eukaryotic cells take cues from their environment and interpret them to enact a response. External stresses can produce a decision between adjusting to behaviors which promote surviving the stress, or enacting a cell death program. The decision to undergo programmed cell death (PCD) is controlled by a complex interaction between nuclear and mitochondrial signals. The mitochondria are highly dynamic organelles that constantly undergo fission and fusion. However, a dramatic shift in mitochondrial morphology toward fission occurs early in the PCD process. We have identified the transcription factor cyclin C as the biochemical trigger for stress‐induced mitochondrial hyper‐fragmentation in yeast (Cooper …

Mechanistic Insights Into The Regulation Of Mitochondrial Fission By Cyclin C, Vidyaramanan Ganesan, Katrina F Cooper, Randy Strich

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Cyclin C is a component of the mediator complex of RNA polymerase II that localizes to the nucleus under normal conditions. In response to stress, cyclin C translocates to the cytosol and mitochondria and mediates stress‐induced mitochondrial fission and apoptosis. The molecular mechanisms by which cyclin C induces mitochondrial fission are unknown. Using in vitro experimental approaches, we sought to investigate the mechanistic basis of cyclin C mediated mitochondrial fission.

Road Dust Correlated With Decreased Reproduction Of The Endangered Utah Shrub Hesperidanthus Suffrutescens, Matthew B. Lewis, Eugene W. Schupp, Thomas A. Monaco

Wildland Resources Faculty Publications

Roads associated with energy development have fragmented much of the Uinta Basin, the Colorado Plateau in general, and other areas of western North America. Beyond reducing available habitat, spreading exotic species, and creating barriers to dispersal, unpaved roads also increase dust loads on plants and pollinators, which may reduce plant growth and reproduction. We studied the effects of an unpaved road on reproduction of an endangered Utah endemic shrub. We measured the size and reproductive output of 156 plants and the dust deposition in plots at increasing distances from the road. We also hand outcrossed 240 flowers from 80 plants …

Assessing Morphological Deformities In Cetaceans: Definition Of Patterns And Quantification With A Case Study (Madeira Island, Ne Atlantic), Erich Dietterle

Masters Theses, 2010-2019

Documenting deformities in cetaceans can lead to understandings in the health of the populations, but also the state of ocean and human health in an area. Deformities like skin lesions can lead to information about local pollution levels or possible diseases, while physical impacts can give insight into vessel traffic or fishing gear entanglement information. Cetaceans encounter threats like vessel strikes and fishing gear entanglements worldwide, but less obvious activities like whale watching or pollution can also have impacts. Studies have been conducted worldwide and around the Madeira Archipelago to document deformities, but there are various descriptions for what is …

Tensorviz: Visualizing The Training Of Convolutional Neural Network Using Paraview, Xinyu Chen, Qiang Guan, Xin Liang, Li-Ta Lo, Simon Su, Trilce Estrada, James Ahrens

Computer Science Faculty Research & Creative Works

Deep Convolutional Networks have been very successful in visual recognition tasks recently. Previous works visualize learned features at different layers o help people to understand how CNNs learn visual recognition tasks. However they do not help to accelerate the training process. We use Paraview to provides both qualitative and quantitative visualization that help understand the learning procedure, tune the learning parameters and direct merging and pruning of neural networks.

Mcb Graduate Students Host Appalachian Regional Cell Conference, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Effect Of Land Use Types On The Distribution Of Carnivore Species In Santa Clara County, Ca., Logan Thompson

Master's Theses

Anthropogenic pressures such as habitat loss and hunting pressures have caused terrestrial mammalian carnivores to decline by 95–99% in many regions of the world. These species are especially susceptible to fragmented habitats and a diminishing food supply because of their slow reproductive rates and high metabolic demands. In biodiversity hotspots such as California, understanding the range of human impacts to species is critical. This project assessed carnivore species distribution and occupancy by placing remote camera traps in a protected Reserve, agricultural, and developed land use types. Mountain lions were only detected in the protected Reserve, and because of this coyotes …

Community Structure And Zonation Of Antarctic Benthic Invertebrates: Using A Remotely Operated Vehicle Under Ice To Define Biological Patterns, Dorota Szuta

Master's Theses

The Ross Sea, Antarctica is a deep bay of the Southern Ocean that exhibits seasonal sea ice and is adjacent to a permanent ice shelf overlying seawater. In 2008 and 2009, imagery of the seafloor under the McMurdo Ice Shelf and under the seasonal ice in the Ross Sea was collected via remotely operated vehicle (ROV) at depths to 300 m. Distinct differences in Antarctic benthic communities were observed over multiple environmental gradients. Species abundance typically exhibited a unimodal distribution with depth with mid-depth peaks, reflecting a food limitation at the deep end and potentially ice disturbance on the shallow …

The Indigenous Sovereign Body: Gender, Sexuality And Performance, Michelle S. A. Mcgeough

Art & Art History ETDs

Gender variance and artist production are not topics that are often discussed within the discipline of art history. In fact gender variance and in particular its relationship to sexual orientation was not a topic studied, much less discussed outside of the medical community until the mid-twentieth century. It was generally thought that sexuality and gender were “biologically determined” and deviation from the heterosexual norm was considered pathological. In contrast, Indigenous nations in Canada and the United States had a very different understanding regarding the relationship between gender, biology, and sexual object of choice. One area that provides us with a …

Seasonal Resource Selection And Habitat Treatment Use By A Fringe Population Of Greater Sage-Grouse, Rhett Boswell

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Movement and habitat selection by Greater Sage-grouse (Centrocercus uropasianus) is of great interest to wildlife managers tasked with applying conservation measures for this iconic western species. Current technology has created small and lightweight GPS (Global Positioning Systems) transmitters that can be attached to sage-grouse. Using GIS software and statistical programs such as Program R, land managers can analyze GPS location data to assess how sage-grouse are geospatially interacting with their habitats. Within the Panguitch Sage-Grouse Management Area (SGMA) thousands of acres of land have been restored or manipulated to enhance sage-grouse habitat; this usually involves removal of pinyon pine …

Identification Of Prognostic Cancer Biomarkers Through The Application Of Rna-Seq Technologies And Bioinformatics, Nathan Wong

McKelvey School of Engineering Graduate Student Theses & Dissertations

MicroRNAs (miRNAs) are short single-stranded RNAs that function as the guide sequence of the post-transcriptional regulatory process known as the RNA-induced silencing complex (RISC), which targets mRNA sequences for degradation through complementary binding to the guide miRNA. Changes in miRNA expression have been reported as correlated with numerous biological processes, including embryonic development, cellular differentiation, and disease manifestation. In the latter case, dysregulation has been observed in response to infection by human papillomavirus (HPV), which has also been established as both oncogenic in cervical cancers and oropharyngeal cancers and favorable for overall patient survival after tumor formation. The identification of …