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Understanding The Goals Of Everyday Instrumental Actions Is Primarily Linked To Object, Not Motor-Kinematic, Information: Evidence From Fmri, Toby Nicholson, Matt Roser, Patric Bach

School of Psychology

No abstract provided.

Uab Opens New Integrative Medicine Clinic, Staff

Browse All News

No abstract provided.

Opposing Functions Of Microglial And Macrophagic Tnfr2 In The Pathogenesis Of Experimental Autoimmune Encephalomyelitis, Han Gao

Open Access Dissertations

In multiple sclerosis (MS), soluble tumor necrosis factor (TNF) is detrimental via activation of TNF receptor 1 (TNFR1), whereas transmembrane TNF is beneficial primarily by activating TNF receptor 2 (TNFR2). Here we investigate the role of TNFR2 in microglia and monocytes/macrophages in experimental autoimmune encephalomyelitis (EAE), a model of MS, by cell-specific gene targeting. We show that TNFR2 ablation in microglia leads to early onset of EAE with increased leukocyte infiltration, T cell activation, and demyelination in the central nervous system (CNS). Conversely, TNFR2 ablation in monocytes/macrophages results in EAE suppression with impaired peripheral T cell activation, and reduced CNS …

2017 Spring Convocation Program, Office Of Communications & Marketing, Morehead State University.

Communications and Marketing Publications Archive

Spring convocation program held on January 11, 2017.

Effects Of Pentachlorophenol And Dichlorodiphenyltrichloroethane On Secretion Of Interferon Gamma (Ifnγ) And Tumor Necrosis Factor Alpha (Tnfα) From Human Immune Cells, Reda Massawe, Leon Drabo, Margaret Whalen

Chemistry Faculty Research

Pentachlorophenol (PCP) and dichlorodiphenyltrichloroethane (DDT) are pesticides that have been widely used and significantly contaminate the environment. Both are found in human blood and have been shown to alter the lytic and binding function of human natural killer (NK) cells. Interferon gamma (IFNγ) and tumor necrosis factor alpha (TNFα) are pro-inflammatory cytokines, which regulate immune responsiveness to pathogens and tumors. Their levels require very tight control to prevent loss of immune competence or excessive inflammation. Here, we examined the capacity of PCP and DDT to alter the secretion of these critical pro-inflammatory cytokines from increasingly reconstituted (more complex) preparations of …

Evolution Of Floral Zygomorphy In Androecium And Corolla In Solanaceae, Jingbo Zhang, Peter Stevens, Wenheng Zhang

Biology Department Faculty Works

In Solanaceae, a group dominated by actinomorphic‐flowered species, floral zygomorphy is frequently observed among the early‐branching clades. Morphological studies indicated that a zygomorphic androecium is much more common than a zygomorphic corolla in the family. Ontogenic studies suggested the evolution of floral zygomorphy in these two whorls is independent. Here, we have examined the evolution of floral symmetry in the androecium and corolla in Solanaceae. The character states of floral symmetry were assembled for androecium and corolla separately, and ancestral state reconstructions were carried out at both the genus and species levels for Solanaceae and its outgroups. Correlation tests were …

Research Explores Social Determinants Of Health Disparities For Obesity And Related Chronic Diseases, Adam Pope

Browse All News

No abstract provided.

A Study Of Early Literacy Interventions On The College And Career Readiness Of High School Students Identified As Struggling Readers In First Grade, Ann Michele Willott

Dissertations

This study examined the college and career readiness of high school graduates who, as struggling first grade readers, successfully completed a specific, research based literacy intervention. By examining students’ Gates MacGinitie Reading Test (GMRT) scores (2002–2009), ACT PLAN test results from 10th grade, ACT test scores from 11th or 12th grade, and course enrollment throughout their high school careers, the degree to which the students were prepared to enter college or the work force was examined. College and career readiness was defined using guidelines and benchmarks outlined in the Common Core State Standards (National Governors Association Center for Best Practice, …

Is It Worth It?: A Review Of The Current Diagnostic Tools And Understandings Of Athletes Suffering With Cte, Melody O'Hara

Biomedical Sciences Undergraduate Research

Increased media coverage on the potential risk of full-contact sports related concussions leading to Chronic Traumatic Encephalopathy (CTE) has led to a proactive response within the scientific community. Scientists are in search of a way to diagnose and prevent the spread of this neurodegenerative disease. In the past, diagnosis of CTE was primarily confirmed by an extensive autopsy of the brain with a considerable amount of tau protein being a strong indicator of CTE. Finding new biomarker imaging tools to assess an individual's brain prior to death is greatly needed. In the past few years, newly developed tau protein probes …

Volume 54, Number 22: January 11, 2017, University Of North Dakota

University Letter Archive

No abstract provided.

Points Of Pride, Georgia Southern University

Points of Pride (2013-2023)

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The Guardian, January 11, 2017, Wright State University Student Body

The Guardian Student Newspaper

Ten page issue of The Guardian, the official student-run newspaper for Wright State University. The Guardian has been published regularly since March of 1965.

Factors Affecting Snowy Plover Chick Survival In A Managed Population, Stephen J. Dinsmore, Eleanor P. Gaines, Scott F. Pearson, David J. Lauten, Kathleen J. Castelein

Institute for Natural Resources Publications

Understanding survival of precocial chicks in the period immediately following hatching has important conservation implications because population growth is often sensitive to post-hatching survival. We studied federally threatened Western Snowy Plover (Charadrius nivosus nivosus) broods at the northern limit of their range in coastal Oregon (n ¼ 1,157) and Washington (n ¼ 84) from 1991 to 2011 in an attempt to understand seasonal, annual, and spatial patterns of chick survival. In Oregon, plover chick survival increased with age, varied between sites, and was greater at sites with predator management. The mean probability of surviving from hatch to fledging at 28 …

Parkinsonian Motor Impairment Predicts Personality Domains Related To Genetic Risk And Treatment Outcomes In Schizophrenia, Juan L. Molina, María Calvó, Eduardo Padilla, Mara Balda, Gabriela González Alemán, Néstor V. Florenzano, Gonzalo Guerrero, Danielle Kamis, Beatriz Molina Rangeon

School of Medicine Publications

Identifying endophenotypes of schizophrenia is of critical importance and has profound implications on clinical practice. Here we propose an innovative approach to clarify the mechanims through which temperament and character deviance relates to risk for schizophrenia and predict long-term treatment outcomes. We recruited 61 antipsychotic naïve subjects with chronic schizophrenia, 99 unaffected relatives, and 68 healthy controls from rural communities in the Central Andes. Diagnosis was ascertained with the Schedules of Clinical Assessment in Neuropsychiatry; parkinsonian motor impairment was measured with the Unified Parkinson's Disease Rating Scale; mesencephalic parenchyma was evaluated with transcranial ultrasound; and personality traits were assessed using …

Investigation On The Structural Variation Of Self-Assembled Lipid Bicellar Mixtures Upon Environmental Stimuli And Addition Of Pegylated Compounds, Ying Liu

Doctoral Dissertations

Bilayered mixed micelle, known as “bicelle”, has been extensively used as the biological membrane models in deciphering membrane-associated proteins. The bicellar mixtures normally constitute of long-chain and short-chain phospholipids in aqueous solutions. Disc-like morphology has been assumed for such mixtures where a bilayer fragment of long-chain phospholipids is sequestered by short-chain lipids at the rim.

Recently, other structures such as vesicles, elongated micelles, and lamellae have also been found in bicelles as temperature, concentration, and salinity vary.

The nano-sized bicellar discs (nanodiscs) and vesicles have great potential to be used as ingredient carriers for imaging and therapy. The research motivation …

Spectator 2017-01-11, Editors Of The Spectator

The Spectator

No abstract provided.

Rates Of Performance Loss And Neuromuscular Activity In Men And Women During Cycling: Evidence For A Common Metabolic Basis Of Muscle Fatigue, Christopher W. Sundberg, Sandra K. Hunter, Matthew W. Bundle

Exercise Science Faculty Research and Publications

The durations that muscular force and power outputs can be sustained until failure fall predictably on an exponential decline between an individual’s 3-s burst maximum to the maximum performance they can sustain aerobically. The exponential time constants describing these rates of performance loss are similar across individuals, suggesting that a common metabolically based mechanism governs muscle fatigue; however, these conclusions come from studies mainly on men. To test whether the same physiological understanding can be applied to women, we compared the performance-duration relationships and neuromuscular activity between seven men [23.3 ± 1.9 (SD) yr] and seven women (21.7 ± 1.8 …

Recurrent Pneumonia Among Japanese Adults: Disease Burden And Risk Factors, Tomoko Ishifuji, Eiichiro Sando, Norihiro Kaneko, Motoi Suzuki, Paul E. Kilgore, Koya Ariyoshi, Konosuke Morimoto, Naoto Hosokawa, Makito Yaegashi, Masahiro Aoshima, Adult Pneumonia Study Group - Japan (Apsg-J)

Department of Pharmacy Practice

Background: In Japan and other societies with rapidly aging populations, recurrent pneumonia (RP) is a major clinical problem yet only limited information exists regarding the burden of this disease.

Methods: A prospective study of adult pneumonia was conducted to investigate the incidence of RP and potential risk factors. From February 1, 2012 to January 31, 2013, patients aged ≥ 15 years who were diagnosed with pneumonia were prospectively enrolled in a representative community hospital located in central Japan. Patients were followed for one-year to evaluate the recurrence of pneumonia and characteristics associated with RP. Cox proportional hazards models were constructed …

Stepchildren’S Communicative And Emotional Journey From Divorce To Remarriage: Predictors Of Stepfamily Satisfaction, Sandra Metts, Paul Schrodt, Dawn O. Braithwaite

Department of Communication Studies: Faculty Publications

This study explores the emotional and communicative profiles of young adults who have experienced a parental divorce and the emergence of a stepfamily to better understand influences on stepfamily satisfaction. Results of regression analyses indicate that strong negative emotions experienced at the time of the divorce are a negative predictor of current stepfamily satisfaction, even after controlling for age at the time of the divorce. In addition, level of open self-disclosure to a stepparent, although not parents, is a positive predictor of current stepfamily satisfaction. Finally, the extent to which the father has now fully explained the circumstances of the …

Cognitive Sociology, Michael W. Raphael

Publications and Research

Cognitive sociology is the study of the conditions under which meaning is constituted through processes of reification. Cognitive sociology traces its origins to writings in the sociology of knowledge, sociology of culture, cognitive and cultural anthropology, and more recently, work done in cultural sociology and cognitive science. Its central questions revolve around locating these processes of reification since the locus of cognition is highly contentious. Researchers consider how individuality is related to notions of society (structures, institutions, systems, etc.) and notions of culture (cultural forms, cultural structures, sub-cultures, etc.). These questions further explore how these answers depend on learning processes …

Pilot Evaluation Of An Online Weight Management Programme, Shona Cawley, Stephen Farrell, Declan G. Byrne, Michael Turner, B. Clune, Daniel Mccartney

Articles

This intervention examined the efficacy of a six-week online weight loss programme. Students and staff of a third level institution (n=183) were recruited to the programme which provided individualised dietary advice for weight loss. Eighty-five participants (mean age 29.7 years, mean BMI 28.9kg/m2, 33% male) met the minimum inclusion criterion of logging on to the study website at least twice. All participants who completed the full six-week programme lost weight (n=31), with significant reductions in mean weight (2.8kg), BMI (0.9kg/m2) and waist circumference (4.1cm) observed between the start and end of the programme (all P5% of their bodyweight, with reductions …

The Effect Of Graphene On Catalytic Performance Of Palladium Nanoparticles Decorated With Fe3o4, Co3o4, And Ni (Oh)2: Potential Efficient Catalysts Used For Suzuki Cross—Coupling, Hany A. Elazab Dr

Chemical Engineering

In this research, we report a scientific investigation of an efficient method used for the synthesis of highly active Palladium Nanoparticles decorated with Fe3O4, Co3O4, and Ni (OH)2 Supported on Graphene as Potential Efficient Catalysts for Suzuki Cross—Coupling. Pd/Fe3O4 nanoparticles supported on graphene nanosheets (Pd/ Fe3O4/G) showed an excellent catalytic activity for Suzuki coupling reactions and recycled for up to four times without loss of catalytic activity. An efficient magnetic catalyst has been successfully synthesized using a simple, reproducible fast and reliable method using microwave irradiation conditions. The prepared catalysts are magnetic as in case of iron and cobalt oxides …

Effects Of Three Road Ice Fighters On Caddisfly Survival, Cata Wedman

JCCC Honors Journal

Since salt and other toxins have affected larvae in other studies, we hypothesized that the samples with table salt, MgCl brine, or beet juice brine will have a lower LT50 than the control group. We also hypothesized the larvae would have the highest mortality in salt and the lowest mortality in beet juice brine. The null hypothesis will be that table salt, beet juice brine, and MgCl samples won’t differ on the control’s group LT50.

An Historical Analysis Of Lab Techniques As Applies To Current Glial Cell Research, Nathan Ostermann

JCCC Honors Journal

The primary focus of neurology, since the beginning, has been the neuron. This is understandable, neuronal networks and nerves being the main communication mechanism between the brain and the rest of the body. However, this focus on neurons has overshadowed and delayed research on the other cells in the brain. Glial cells, or neuroglia, are defined as all cells in the brain that are not electrically excitable neurons or vascular cells. This definition of glial cells introduced by Rudolf Ludwig Karl Virchow in 1858. Until relatively recently, the idea that glial cells are simply passive elements of the brain that …

Petrographical And Geochemical Changes In Bosnian Stalagmites And Their Palaeo-Environmental Significance, Veronica Chiarini, Isabelle Couchoud, Russell Drysdale, Petra Bajo, Simone Milanolo, Silvia Frisia, Alan Greig, John Hellstrom, Jo De Waele

International Journal of Speleology

Detailed petrographic observations have been coupled with trace element and δ¹³C - δ¹⁸O analyses in order to investigate their dynamics in two Holocene Bosnian speleothems. The potential of this multiproxy approach in providing a means to extract palaeo-environmental information from stalagmites whose stable isotope signals are noisy and without obvious trends has been tested. The studied stalagmites are mostly characterized by columnar microcrystalline fabric. At the sub-millimetre scale of lamination, different microcrystalline columnar sub-types (open and closed) have been detected and classified on the basis of the observed porosity and the crystallite size. The presence of …

Human-Nonhuman Chimeras, Ontology, And Dignity: A Constructivist Approach To The Ethics Of Conducting Research On Cross-Species Hybrids, Jonathan M. Vajda

The Hilltop Review

Developments in biological technology in the last few decades highlight the surprising and ever-expanding practical benefits of stem cells. With this progress, the possibility of combining human and nonhuman organisms is a reality, with ethical boundaries that are not readily obvious. These inter-species hybrids are of a larger class of biological entities called “chimeras.” As the concept of a human-nonhuman creature is conjured in our minds, either incredulous wonder or grotesque horror is likely to follow. This paper seeks to mitigate those worries and demotivate reasonable concerns raised against chimera research, all the while pressing current ethical positions toward their …

Disciplinary Differences In Out-Of-School High School Science Experiences And Influence On Students’ Engineering Choices, Allison Godwin, Gerhard Sonnert, Philip M. Sadler

Journal of Pre-College Engineering Education Research (J-PEER)

Participation from a variety of students is important to the long-term growth of the engineering field. Much of the research on engineering recruitment or career choice has focused on engineering as a whole, even though engineering disciplines are varied in student participation and focus. This work examines how students’ out-of-school interests and experiences in high school predict the likelihood of choosing a career in a particular engineering discipline. Out-of-school experiences offer more unstructured ways for students to meaningfully engage with science and engineering outside of the confines of the classroom. These experiences offer opportunities to spark particular science interests not …

Role Of Nuclear Pharmacist In Clinical Translation Of Positron Emission Tomography (Pet) Radiopharmaceuticals And Environmental Monitoring Of Facility, Reiko Oyama

Pharmaceutical Sciences ETDs

There have been many changes in nuclear medicine and molecular imaging field as several radiopharmaceuticals have recently been approved and many others on the horizon. Ensuring the compliance with the increasingly aggressive national, federal, and state regulatory has become a critical piece of PET manufacturing and Nuclear Pharmacy.

As a nuclear pharmacist, I have been searching for the way I can better contribute to the progress of this field with an ultimate goal of proving safe and effective healthcare to the patients. In order to do so, strengthening my expertise is essential. In this thesis, I would like to capture …

A Comparative Genomic Analysis Of Putative Pathogenicity Genes In The Host-Specific Sibling Species Colletotrichum Graminicola And Colletotrichum Sublineola, Ester A. S. Buiate, Katia Viana Xavier, Neil Moore, Maria F. Torres, Mark L. Farman, Christopher L. Schardl, Lisa J. Vaillancourt

Plant Pathology Faculty Publications

Background: Colletotrichum graminicola and C. sublineola cause anthracnose leaf and stalk diseases of maize and sorghum, respectively. In spite of their close evolutionary relationship, the two species are completely host-specific. Host specificity is often attributed to pathogen virulence factors, including specialized secondary metabolites (SSM), and small-secreted protein (SSP) effectors. Genes relevant to these categories were manually annotated in two co-occurring, contemporaneous strains of C. graminicola and C. sublineola. A comparative genomic and phylogenetic analysis was performed to address the evolutionary relationships among these and other divergent gene families in the two strains.

Results: Inoculation of maize with C. sublineola …

Oceanographic Data In Rhode Island Waters Ocg 150, Joanna Burkhardt

Library Impact Statements

No abstract provided.