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2017

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Implementing "The Asean Regional Guidelines On Competition Policy" In Thailand, Indonesia, Singapore And Vietnam: Challenges And Opportunities, Sathita Wimonkunarak Jan 2017

Implementing "The Asean Regional Guidelines On Competition Policy" In Thailand, Indonesia, Singapore And Vietnam: Challenges And Opportunities, Sathita Wimonkunarak

Chulalongkorn University Theses and Dissertations (Chula ETD)

The ASEAN Regional Guidelines on Competition Policy was created to be a common framework for competition policy, which includes competition law and its enforcement for all ASEAN Member States. Implementing the ASEAN Regional Guidelines on Competition Policy is an important tool for achieving the goals of the ASEAN economic integration by level playing field for all market participants to create fair competition environment, which help turning ASEAN into highly competitive economic region and facilitate trade liberalization in ASEAN.These are considered the ultimate opportunities in implementing the Guidelines among ASEAN Member States. However, this study found that Guidelines cannot fully function …

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Synthesis And Properties Of Acrylonitrile-Butadiene-Styrene Copolymer Containing Silica Nanoparticles, Charungkit Chaikaew Jan 2017

Synthesis And Properties Of Acrylonitrile-Butadiene-Styrene Copolymer Containing Silica Nanoparticles, Charungkit Chaikaew

Chulalongkorn University Theses and Dissertations (Chula ETD)

The aim of this research is to develope acrylonitrile butadiene styrene composite reinforced with hydrophobic silica nanoparticles. In this study, in-situ synthesis of ABS rubber particles containing hydrophobic silica nanoparticles (HDTMS-silica) was carried out. Firstly, three of HDTMS-silicas (HDTMS-silica1, HDTMS-silica2, and HDTMS-silica3) were prepared by silanization of SiO2 nanoparticle with hexadecyltrimethoxysilane (HDTMS : SiO2 wt ratios of 1 : 1, 2 : 1, and 3 : 1) in an emulsion system. Then, HDTMS-silica/styrene and acrylonitrile mixture was fed into a polybutadiene latex reactor. Following that, graft copolymerization was carried out using persulfate initiator at temperature of 65 oC for 3.5 …

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Measurement Of Eye Lens Dose In Interventional Radiologist From Tace Procedures Using Osld, Mananchaya Vimolnoch Jan 2017

Measurement Of Eye Lens Dose In Interventional Radiologist From Tace Procedures Using Osld, Mananchaya Vimolnoch

Chulalongkorn University Theses and Dissertations (Chula ETD)

For routine clinical service at Section of Interventional Radiology, Department of Radiology, King Chulalongkorn Memorial Hospital (KCMH), TACE procedure has been one of the high exposure procedures, which result in increasing eye lens dose in interventional radiologists. Thus, radiation dose should be evaluated in interventional radiology staff who may receive high eye lens dose. Currently, there is insufficient information to comply with the ICRP dose limit on the occupation exposure to the eye lens. One of the factors affecting the eye lens dose is the variation in tube directions in the interventional radiology (IR) laboratories. A preliminary study about tube …

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Ct Number And Electron Density Relationship For Photon Dose Calculation In Head And Neck, Chest, Spine And Pelvic Regions, Siriporn Wong Jan 2017

Ct Number And Electron Density Relationship For Photon Dose Calculation In Head And Neck, Chest, Spine And Pelvic Regions, Siriporn Wong

Chulalongkorn University Theses and Dissertations (Chula ETD)

CT images supply the HU information that relates to electron density (ρe). The ρe is important for tissue inhomogeneity correction for accurate dose calculation. The purpose of this study was to evaluate the dosimetric effect on CT images on different kVp setting using single HU-ρe curve. Anthropomorphic phantom was scanned using Siemens-SOMATOM Definition AS with 120 kVp setting and used as a reference image set. The procedures were repeated with DECT option (80/140 kVp), 80 and 140 kVp. The 120 kVp HU-ρe relationship curve from Gammex 467 tissue characterization phantom was created and applied into Eclipse treatment planning system. The …

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Radiation Dose And Image Quality In Chest Region Using Single- And Dual-Energy Ct: Phantom Study, Taninchai Jutawiriya Jan 2017

Radiation Dose And Image Quality In Chest Region Using Single- And Dual-Energy Ct: Phantom Study, Taninchai Jutawiriya

Chulalongkorn University Theses and Dissertations (Chula ETD)

Chest CT examinations are routinely performed by using single energy protocol (SE). As CT had been evolved by using dual energy protocol (DE), the patients with underlying lung nodules or pulmonary nodules will be followed up by CT examination several times. The purpose of this study is to study the radiation dose and image quality between single-energy CT (SECT) and dual-energy CT (DECT) protocols in chest phantom at King Chulalongkorn Memorial Hospital. The Lungman Kyoto Kagaku phantom inserted by five simulated lesions of various diameters was scanned by dual-source CT system (Somatom Force, Siemens Healthineers). The acquisition protocols consist of …

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Involvement Of Notch Signaling In Interleukin-4-Stimulated Human Macrophages, Naunpun Sangphech Jan 2017

Involvement Of Notch Signaling In Interleukin-4-Stimulated Human Macrophages, Naunpun Sangphech

Chulalongkorn University Theses and Dissertations (Chula ETD)

Macrophages respond to various stimuli, resulting in distinct effector phenotypes that range from LPS-stimulated proinflammatory to IL-4-activated pro-healing phenotype. The regulatory mechanism of this polarization is not fully understood. Notch signaling pathway is a conserved signaling pathway involved in polarization of macrophages, especially proinflammatory macrophages. However, the role of Notch signaling in IL-4 stimulated macrophages (M(IL-4)) is not well defined. PPARgamma is a signature nuclear receptor in M(IL-4) that function mainly in regulating lipid metabolism. There are many reports that revealed the interaction of Notch signaling and PPARgamma in various cells but not in macrophages. In this study, the interaction …

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Development Of Gold Nanoparticle-Based Lateral Flow Immunoassay For Detection Of Pathogenic Leptospiral Antigen, Prayoon Lae-Ngee Jan 2017

Development Of Gold Nanoparticle-Based Lateral Flow Immunoassay For Detection Of Pathogenic Leptospiral Antigen, Prayoon Lae-Ngee

Chulalongkorn University Theses and Dissertations (Chula ETD)

Leptospirosis, caused by pathogenic Leptospira spp., is a global re-emerging zoonosis and endemic disease in tropical and sub-tropical countries including Thailand. Point-of-care testing (POCT) for rapid diagnosis of leptospirosis is needed for prompt and appropriate treatment particularly in resource-poor settings. Lateral flow immunoassay (LFA)-based POCT devices are rapid, user friendly, cheap, have one-step analysis, and need no sophisticated equipment. LipL32 is a common target for diagnostic tests of leptospirosis because it is the major outer membrane protein (OMP) that is specific and highly conserved among pathogenic Leptospira. This study aimed to develop the gold nanoparticle (AuNP)-based LFA for detection of …

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Characterization Of Antimicrobial-Resistant Nontyphoidal Salmonella Isolated From Humans And Food Animals In Thailand 172252256, Sirirat Luk-In Jan 2017

Characterization Of Antimicrobial-Resistant Nontyphoidal Salmonella Isolated From Humans And Food Animals In Thailand 172252256, Sirirat Luk-In

Chulalongkorn University Theses and Dissertations (Chula ETD)

The emergence and increase of resistance to antimicrobial agents, especially to extended-spectrum cephalosporins (ESCs) and fluoroquinolones in nontyphoidal Salmonella have recently become a serious therapeutic problem. The objectives of this study were to characterize antimicrobial resistance mechanisms, the clonality, and plasmid profiles among nontyphoidal Salmonella isolates from human and food animals in Thailand. A total of 897 nontyphoidal Salmonella isolates, 617 isolates from human and 280 isolates from food animal in Thailand during 2005 to 2007 and 2012 to 2016 were included in this study. The significantly higher resistance rates were found in S. Choleraesuis compared with other serotypes to …

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Antimicrobial Effect Of High Dose Ascorbate In Mouse Model With Bacterial Infection, Chulamartd Wirapakorn Jan 2017

Antimicrobial Effect Of High Dose Ascorbate In Mouse Model With Bacterial Infection, Chulamartd Wirapakorn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Ascorbate or Vitamin C is a vitamin that is important to the body. It contributes to the immunity, involves the collagen formation, acts as an antioxidant and has the ability to destroy cancer cells and bacteria. These abilities depend on the concentration of ascorbate. Bactericidal properties of ascorbate were interesting, especially in the high concentrations. Staphylococcus aureus, Pseudomonas aeruginosa, Acinetobacter baumannii, and Escherichia coli are a common etiologies of nosocomial infection in Thailand and worldwide. These bacteria have developed mechanisms of antibiotics resistance and cause more violence in the disease. Hence, the time-killing assay was used to explore the bactericidal …

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Immune Response In Pythiosis Patients Treated With Pythium Insidiosum Antigen (Pia), Navaporn Worasilchai Jan 2017

Immune Response In Pythiosis Patients Treated With Pythium Insidiosum Antigen (Pia), Navaporn Worasilchai

Chulalongkorn University Theses and Dissertations (Chula ETD)

Immunotherapy using Pythium insidiosum antigen (PIA) is one of the combination treatment for P. insidiosum infected patients along with amputation and certain antifungal agents. The protocol of first prime (day0) after diagnosis and six booster doses (at 0.5, 1, 1.5, 3, 6, 12 months; mo.) along a year period were performed based on previous study. The switching of T-helper2 (Th2) to Th1 after immunotherapy along with the clinical improvement in equine and rabbit models were revealed whereas studies in human are very limited. To investigate the immune response in PIA treated pythiosis patients, cytokine profile (CMI response), P. insidiosum specific …

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Induction Of Interleukin-1 Receptor Antagonist (Il-1ra) By Porcine Reproductive And Respiratory Syndrome Virus (Prrsv), Teerawut Nedumpun Jan 2017

Induction Of Interleukin-1 Receptor Antagonist (Il-1ra) By Porcine Reproductive And Respiratory Syndrome Virus (Prrsv), Teerawut Nedumpun

Chulalongkorn University Theses and Dissertations (Chula ETD)

Porcine respiratory and reproductive syndrome virus (PRRSV) is one of the major pathogens affecting pig production industry worldwide. Impaired innate and adaptive immune responses are evidenced through the course of PRRSV infection. Several evidences indicate that PRRSV suppresses host immune responses via several immune evasion strategies. Interleukin-1 receptor antagonist (IL-1Ra) is known as an early inhibitory cytokine that suppresses innate immune functions and T lymphocyte responses. The aims of this study were to explore the induction of IL-1Ra by PRRSV and the negative immunomodulatory effects of PRRSV-induced IL-1Ra on porcine immune responses. In this study, the previous monocytes-derived dendritic cells …

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Lipoic Acid-Incorporated Calcium Carbonate Nanoparticlesfor Controlling Of Adipose Derived Stem Cells (Adscs) Differentiation And Adipocyte Function, Sarocha Cherdchom Jan 2017

Lipoic Acid-Incorporated Calcium Carbonate Nanoparticlesfor Controlling Of Adipose Derived Stem Cells (Adscs) Differentiation And Adipocyte Function, Sarocha Cherdchom

Chulalongkorn University Theses and Dissertations (Chula ETD)

CaCO3 NPs has received a growing interest due to its potential properties as a safe drug carrier. The LA-CaCO3 NPs were synthesized by a chemical precipitation method and characterized using transmission electron microscopy, thermogravimetric analysis, and zeta potential measurement. We used LA-CaCO3 NPs to evaluate their therapeutic effects in lipid accumulation, lipolysis, adipogenesis, and adipokines expression in ADSCs and differentiated adipocytes. The average particle sizes were observed to be 10-20 nanometers. Thermogravimetric analysis results confirmed the percentages of LA in CaCO3 NPs. The zeta potential showed a negative charge -30.9 mV. Our findings indicated that LA-CaCO3 NPs were apparently more …

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Effects Of Genistein On Non-Alcoholic Steatohepatitis (Nash) Induced By High-Fat High-Fructose Diet In Bilateral Ovariectomized Rats, Sudaporn Pummoung Jan 2017

Effects Of Genistein On Non-Alcoholic Steatohepatitis (Nash) Induced By High-Fat High-Fructose Diet In Bilateral Ovariectomized Rats, Sudaporn Pummoung

Chulalongkorn University Theses and Dissertations (Chula ETD)

To investigate the effects of genistein on estrogen deficiency with high-fat high-fructose (HFHF) diet-induced NASH rats. Female Sprague-Dawley rats (n=48) were randomly divided into ovariectomized (OVX) and non-ovariectomized (non-OVX) group. Both rat groups, further allocated into 3 subgroups; controls, rats fed with HFHF diet (NASH), and rats fed with HFHF diet plus daily 16 mg/kg BW of genistein (NASH+Gen) for 8 weeks. Serum samples were collected for liver enzymes (AST and ALT) and TNF-α level analysis. Liver tissue samples were harvested for histopathology, hepatic lipid accumulation (oil red o stained, FFA and TG level), hepatic lipid peroxidation (MDA level), hepatic …

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Evaluation Of Lipid Accumulation And Lipolysis Activity In Human Subcutaneous Adipocytes And Human Visceral Adipocytes By Α-Lipoic Acid, Α-Lipoic Acid-Incorporated Caco3 Nanoparticles And Caffeine., Sunisa Kaewdang Jan 2017

Evaluation Of Lipid Accumulation And Lipolysis Activity In Human Subcutaneous Adipocytes And Human Visceral Adipocytes By Α-Lipoic Acid, Α-Lipoic Acid-Incorporated Caco3 Nanoparticles And Caffeine., Sunisa Kaewdang

Chulalongkorn University Theses and Dissertations (Chula ETD)

Recently, much attention has been paid to natural plant-derived compounds as an alternative strategy for developing anti-obesity agents with minimal detrimental effects. Among various natural compounds, caffeine (1, 3, 7-trimethyl xanthine) and alpha lipoic acid (1, 2-dithiolane-3-pentanoic acid; LA) are the natural agents which show a promising result in decreasing fat deposit. Moreover, we have improved efficiencies of LA by CaCO3 NPs because LA had low bioavailability. In the present study, we investigated the effect of combination between caffeine and LA-CaCO3 NPs in lipid accumulation reduction and lipolysis stimulation in human subcutaneous adipocytes and human visceral adipocytes. Our results showed …

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Effects Of Curcumin On Oxidative Stress, Inflammation And Apoptosis In L-Arginine Induced Acute Pancreatitis In Mice, Thidarat Chingchit Jan 2017

Effects Of Curcumin On Oxidative Stress, Inflammation And Apoptosis In L-Arginine Induced Acute Pancreatitis In Mice, Thidarat Chingchit

Chulalongkorn University Theses and Dissertations (Chula ETD)

L-arginine (L-arg) is an amino acid that has been used to induce acute pancreatitis (AP) in mice. Curcumin is an active ingredient constituent of rhizomes of the plant Curcuma longa Linn. It has been used for the treatment of inflammatory conditions and shown to exhibit a variety of biological activities such as anti-inflammatory and anti-oxidant. The present study aims to examine the effects of curcumin on oxidative stress, inflammation and apoptosis in AP. Male ICR mice were randomly divided into 4 groups. 1) Control group, mice will be received i.p. of 1% DMSO as a vehicle. 2) AP group, mice …

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Effect Of Calcium Citrate In Calcium Carbonate Nanoparticles On Hk-2 Cells In Acidic Environment, Tipagorn Udomsinsirikul Jan 2017

Effect Of Calcium Citrate In Calcium Carbonate Nanoparticles On Hk-2 Cells In Acidic Environment, Tipagorn Udomsinsirikul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Metabolic acidosis exerts several cellular and tissue dysfunctions, such as increases mineral bone and protein degradation, induces inflammation, oxidative stress and cell death. These complications lead to multiple organ failure, including chronic kidney disease. Sodium bicarbonate and Shohl's solution are commonly used to treat metabolic acidosis. However, these agents cause frequent gastrointestinal adverse effects. Hence, we invented the new calcium carbonate nanoparticles to use as a drug delivery system for carrying citrate to renal cell which we hypothesize to reduce adverse effects of metabolic acidosis. We studied the physical characteristics and pharmacological effects of calcium citrate nanoparticle (Cacit) and calcium …

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Carotenoids And Metabolism Of The Green Microalga Chlorococcum Sp. 8367re Under Stress Conditions, Kantima Janchot Jan 2017

Carotenoids And Metabolism Of The Green Microalga Chlorococcum Sp. 8367re Under Stress Conditions, Kantima Janchot

Chulalongkorn University Theses and Dissertations (Chula ETD)

Green microalgae are one of the natural resources for productions of various and beneficial bioactive compounds, such as UV-screening compounds and carotenoids. This study focuses on the changes of carotenoids and metabolisms in the green microalga Chlorococcum sp. 8367RE under stress conditions. The results showed that stresses by salt, light, drought, and nitrogen starvation affected on alterations of morphological characteristics. Interestingly, size of cells culturing under salt stresses dramatically increased. It should be noted that KCl stress caused the enlargement of cell sizes approximately 5 folds. Carotenoids were identified and quantified by using ultra-high performance liquid chromatography (UHPLC) and mass …

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Functional Characterization Of Natural Sunscreen Compound Mycosporine-2-Glycine From Extremophilic Cyanobacterium Halothece Sp. Pcc 7418 In Macrophage Cell Line And Fresh Water Cyanobacterium, Supamate Tarasuntisuk Jan 2017

Functional Characterization Of Natural Sunscreen Compound Mycosporine-2-Glycine From Extremophilic Cyanobacterium Halothece Sp. Pcc 7418 In Macrophage Cell Line And Fresh Water Cyanobacterium, Supamate Tarasuntisuk

Chulalongkorn University Theses and Dissertations (Chula ETD)

Mycosporine-2-glycine (M2G) is a rare UV-screening compound in a group of mycosporine-like amino acids (MAAs). This molecule is found in only two cyanobacteria; Euhalothece sp. LK-1 and Aphanothece halophytica (Halothece sp. PCC 7418). The structure of M2G composed of 4-deoxygadusol as a core structure, attached by 2 molecules of glycine at C1 and C3 positions. M2G has a maximal adsorption at 331 nm and a better antioxidative activity than other MAAs. Thus, it is interesting in determination of other activities for further cosmeceutical and pharmaceutical applications. In this study, a high purity M2G was successfully extracted and purified from Halothece …

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The Effect Of Uncertainty Management Program On Quality Of Life Among Vietnamese Women With Post Mastectomy, Xuan Ha Thi Nhu Jan 2017

The Effect Of Uncertainty Management Program On Quality Of Life Among Vietnamese Women With Post Mastectomy, Xuan Ha Thi Nhu

Chulalongkorn University Theses and Dissertations (Chula ETD)

The aim of this study was to test the effect of the Uncertainty Management Program (UMP) on quality of life among Vietnamese women at 3-weeks post mastectomy. The quasi-experimental design with posttest only was conducted in 115 women with post mastectomy who were assigned in experimental group (n=57) and control group (n=58). The experimental group received the UMP and routine care while the control group received only routine care. Participants were assessed at 3-weeks post mastectomy using the modified Quality of Life Index Scale Vietnamese version with Cronbach's alpha coefficient of .81. It was found that at 3-weeks post-mastectomy, the …

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Patient's Perception And Satisfaction On Dental Implant Therapy By Postgraduate Dental Students And Experienced Dentists, Pat Vipattanaporn Jan 2017

Patient's Perception And Satisfaction On Dental Implant Therapy By Postgraduate Dental Students And Experienced Dentists, Pat Vipattanaporn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: To evaluate and compare patient's perception and satisfaction between patients who received dental treatment from postgraduate dental students and experienced dentists. Material and methods: This descriptive cross-sectional study was performed in patients who received the dental implant from Faculty of dentistry Chulalongkorn University. A data collection of patient's perception and satisfaction was done by questionnaire which was sent by mail. The questionnaire contained 23 statements including 7 statements of demographic data, 7 statements of perception, and 9 statements of satisfaction. The patient had to answer through the one-best-answer multiple choices and visual analog scale (VAS). Results: The 382 participants …

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In Vitro Effect Of L-Ascorbic Acid On Gingival Fibroblast To Regulate Wound Healing., Tatcha Chaitrakoonthong Jan 2017

In Vitro Effect Of L-Ascorbic Acid On Gingival Fibroblast To Regulate Wound Healing., Tatcha Chaitrakoonthong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background and Objective: Besides closing the wound by intrinsic properties like migration and proliferation, gingival fibroblasts produce a major source of extracellular matrix especially collagen and play a major role in oral wound healing. Vitamin C or L-ascorbic acid has diverse functions in the body, including an essential role in hydroxylation reactions which is necessary for collagen formation. Whether L-ascorbic acid can promote gingival wound healing through inducing proliferation of fibroblasts is of our interest. The aim of this study is to evaluate the effect of L-ascorbic acid on gingival fibroblasts behaviors to promote wound healing in vitro. Materials and …

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Comparative Study Of In Vivo Bone Regeneration Using Chitosan/Dicarboxylic Acid Scaffold Implanted With Human Periodontal Ligament Cells, Teerawat Sukpaita Jan 2017

Comparative Study Of In Vivo Bone Regeneration Using Chitosan/Dicarboxylic Acid Scaffold Implanted With Human Periodontal Ligament Cells, Teerawat Sukpaita

Chulalongkorn University Theses and Dissertations (Chula ETD)

After tooth loss, a consequent atrophy of the alveolar process always takes place and adversely affect the reconstruction process especially by dental implant. A novel chitosan/dicarboxylic acid scaffold (CS/DA scaffold) has been developed and proven to be an excellent candidate material in bone tissue engineering. This study aimed to evaluate the effects of a CS/DA scaffold with and without seeded primary human periodontal ligament cells (hPDLCs) in mouse calvarial defect model. Eighteen mice were divided into 3 groups of 6 each. Four-millimeter calvarial defects were created on both side of parietal bone and implanted with either CS/DA scaffold or CS/DA …

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Induction Of S100a7 Expression From Mechanical Stress-Induced Human Dental Pulp Cells And Its Effect On Osteoclastogenesis, Hataichanok Charoenpong Jan 2017

Induction Of S100a7 Expression From Mechanical Stress-Induced Human Dental Pulp Cells And Its Effect On Osteoclastogenesis, Hataichanok Charoenpong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Mechanical injuries of dental pulp tissues could lead to root resorption by osteoclast/odontoclast. S100A7 has been demonstrated to involve in inflammatory processes and potentially involved in bone destruction. However, the roles of S100A7 in dental pulp have not been reported. Therefore, this this study aimed to investigate the effect of mechanical stress on S100A7 expression in human dental pulp cells (hDPCs) and to investigate the effect of S100A7 protein on osteoclast differentiation. HDPCs were stimulated with in vitro compressive loading. Cell viability was determined using MTT assay. Real-time PCR (qPCR) and ELISA were utilized to determine the mRNA and protein …

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The Application Of Prostacyclin In Promoting Angiogenesis Of Dental Pulp Tissue In A Three Dimensional Organ Culture System, Sonntana Seang Jan 2017

The Application Of Prostacyclin In Promoting Angiogenesis Of Dental Pulp Tissue In A Three Dimensional Organ Culture System, Sonntana Seang

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: Dental pulp vitality can be threatened by carious or iatrogenic exposure that can lead to pulp tissue loss. The formation of a vascular network is crucial to provide a suitable environment for tissue regeneration. Thus, promoting angiogenesis is essential for successful pulpal repair in regenerative endodontics therapy. Iloprost, a prostacyclin analog, promotes vascularization in several organs such as, heart, lung, and corneal. Previously, it has been demonstrated that, iloprost induced pulpal blood flow and enhanced dentin formation in a rat mechanical pulp exposure model. However, the angiogenic effect of iloprost on the human dental pulp vasculature remains unknown. Objective: …

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Differential Dendritic Cell Responses To Candida Species, Thu Nguyen Ngoc Jan 2017

Differential Dendritic Cell Responses To Candida Species, Thu Nguyen Ngoc

Chulalongkorn University Theses and Dissertations (Chula ETD)

Mannan in the outermost layer of Candida cell wall may be the first molecules that interact with host dendritic cells (DCs) and activate immune responses that determine disease outcomes. However, little is known how different mannan structures of common Candida species affect DC activation and T cell responses. Thus, this work compared the effects of mannans of Candida albicans, Candida tropicalis, Candida glabrata, Candida krusei, Candida parapsilosis and Candida dubliniensis on bone marrow-derived DC (BMDC) responses in mice. C. albicans and C. tropicalis mannan could not activate DC maturation, however, they induced IFN-gamma production which consequently provoked Th1 responses. C. …

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Metal-Salen Derivatives For Electro-Reduction Of Carbon Dioxide, Kantima Chitchak Jan 2017

Metal-Salen Derivatives For Electro-Reduction Of Carbon Dioxide, Kantima Chitchak

Chulalongkorn University Theses and Dissertations (Chula ETD)

Copper(II) salen, salophen-based ligands, and their corresponding copper complexes were prepared and utilized for the electrocatalytic reduction of carbon dioxide. Controlled-potential electrolysis of copper(II) salen electrocatalyst with carbon dioxide in non-aqueous solution was investigated to obtain the optimized electrolysis condition including the applied potential and proton donor quantity. With the applied potential of –2.10 V, carbon monoxide (3.50-16.30%) was obtained as the only product in gas phase. Methane was additionally found with the addition of proton donor and its maximum percentage (0.39 ± 0.00%) were obtained from the electrolysis with 25.00 mM proton donor and 2.00 mM copper(II) salen. Moreover, …

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Functional Surfactants In Lubricant For Microelectronic Industry, Chuenkamol Khongphow Jan 2017

Functional Surfactants In Lubricant For Microelectronic Industry, Chuenkamol Khongphow

Chulalongkorn University Theses and Dissertations (Chula ETD)

The functional surfactants, as the additional additives in the standard glycol-based lubricant were studied and optimized to reduce and protect the surface of the magnetic read/write head from deposited contaminants during the lapping processes. The scanning electron microscopy (SEM) and energy-dispersive x-ray spectroscopy (EDS) results identified that the black contamination was bismuth (Bi) particles, came out from lapping plate during the lapping process due to wear. Selected surfactants exhibited the results in reduce and prevent the deposition of contaminants by forming the micelle beyond their critical micelle concentration (CMC) values. We found that both polyethoxylate alcohol (PEAL) and quaternary amines …

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Mixed Metal Oxide Catalysts Derived From Natural Sources For Production Of Fatty Acid Methyl Esters, Wayu Jindapon Jan 2017

Mixed Metal Oxide Catalysts Derived From Natural Sources For Production Of Fatty Acid Methyl Esters, Wayu Jindapon

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objectives of this research are to study active sites of Ca-based catalysts derived from calcite (CaCO3) and dolomite (CaMg(CO3)2), and to clarify catalytic effect of MgO in the calcined dolomite as catalyst in transesterification of palm oil with methanol. Firstly, the effects of calcination temperature on evolution of MgO in dolomite and its catalytic activity were studied. The MgO containing in the calcined dolomite was not active, while the main active site was CaO. However, Ca and Mg mixed oxides obtained from calcined dolomite had higher activity than that prepared by physical mixing in which calcite and magnesite (MgCO3) …

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Synthesis Of Puerarin-Gold Nanoparticles For Transdermal Delivery, Kwanruen Chanpeng Jan 2017

Synthesis Of Puerarin-Gold Nanoparticles For Transdermal Delivery, Kwanruen Chanpeng

Chulalongkorn University Theses and Dissertations (Chula ETD)

Puerarin (Pur) is herbal medicine that its inflammatory response but low solubility to reduce activity. Thus, the aim of this study was to synthesize q188-kappa-carrageenan@Pur@gold nanoparticles (q188-κ-c@Pur@AuNPs) for enhancing solubility and transdermal delivery. The κ-c was synthesized by quaternization of κ-c with 25% (v/v) q188, and the q188-κ-c @AuNPs was prepared by reducing HAuCl4 into AuNPs by using 25% (v/v) q188-κ-c as reducing and stabilizing agents. The highest degree of quaternization (%DQ) at 21.12% was found q188 addition, which was calculated from 1H NMR. The solubility of the q188-κ-c derivatives was 43.7±0.01%, which higher than κ-c. The size of synthesized …

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Effect Of Corrosion Inhibitors In Lubricant For Electronic Industry, Natclitta Maipul Jan 2017

Effect Of Corrosion Inhibitors In Lubricant For Electronic Industry, Natclitta Maipul

Chulalongkorn University Theses and Dissertations (Chula ETD)

The selected functional polymers and fatty esters of poly)1-butene pyrrolidone) (PP) and propylene glycol monostearate (PG) were investigated and applied to use as the corrosion inhibitors for protecting material removal during read/write head lapping processes in hard disk drive (HDD) production. Potentiodynamic polarization measurement was used to study their corrosion behaviors against antiferromagnetic materials (IrMn) which are the most sensitive materials in the head structure. Corrosion rate of PP- and PG-modified lubricants were 0.086 and 0.084 Å/min, respectively, while standard lubricant was 0.111 Å/min. Moreover, the leaching out of metallic atoms was investigated by using inductively couple plasma mass spectroscopy …

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