Digital Commons Network^™

Nanopore Thermodynamics Via Infrared Laser Heating, Christopher Angevine

Theses and Dissertations

Single molecule nanopore spectroscopy is a label-free method for characterizing a wide variety of water-soluble molecules. Recently there have been efforts to expand nanopore sensing to new areas of study. Forensic investigators require an easy to deploy method to identify an unknown number of contributors in a solution. Currently there is no easily available method to distinguish between a single or multiple contributor solution of DNA before being processed by more advanced analytical techniques which has led to wasted time and resources increasing the backlog of samples waiting to be processed. In this work we present a new nanopore technique …

Parent-Fostered Enrichment Activities And Academic Outcomes In Middle Childhood, Princess-Melissa T. Washington-Nortey

Theses and Dissertations

Despite numerous educational reforms, elementary school children in the United States continue to lag behind their peers from other developed countries on reading, math and science outcomes. Many interventions focus on strategies aimed at increasing the amount of classroom work children undertake. However, the key to improving outcomes may lie in out of school enrichment activities that facilitate learning. Drawing from Eccles Expectancy-Value theory(Simpkins, Fredricks, & Eccles, 2012), the current study focuses on assessing the impact of parent-fostered enrichment activities on child academic outcomes in the first three years of elementary school. Using secondary data from Early Childhood Longitudinal Study …

Investigation Of The Effects Of Ionic Interactions In Peptide And Protein Structure, Aimee Lorts

College of Graduate Studies: Theses & Dissertations

Proteins and their unique structures are important due to their involvement in every cellular task, but the protein can only function properly when it is in the correct fold. β-sheet peptides and collagen were observed via structural studies. Circular dichroism (CD) determines a protein’s secondary structure. WKWK, a beta-sheet peptide, is known to dissolve in aqueous solutions. However, WKWK was observed to precipitate out of deionized water. To investigate the cause of this precipitation, Inductively Coupled Plasma Mass Spectroscopy (ICP-MS) was used to determine the ion content of the water. Elevated sodium ion concentrations were found to disrupt the stabilizing …

Antibiotics And Antibiotic-Resistant Bacteria In Coastal Plain Streams, Jason Duff

College of Graduate Studies: Theses & Dissertations

Streams across the United States and globally are influenced by environmental contamination, including antibiotics, which enter streams due to widespread use and multiple pathways into the environment. Antibiotics are also likely to enter streams in mixture with other contaminants that alter the effects on aquatic organisms. Furthermore, antibiotic-resistant bacteria enter streams through similar pathways as antibiotics with implications for natural microbial communities. Therefore, understanding the presence and effects of antibiotic-contaminant mixtures and antibiotic-resistant bacteria in streams is important for resource management.

Chapter one describes an experiment that tested the hypothesis that the antibiotic tetracycline (TC) alone influences phytoplankton communities differently …

Silver Nanoparticle Fate And Accumulation In The Aquatic Food Web Of Stream Microcosms, Stefan J. Petersen

College of Graduate Studies: Theses & Dissertations

Silver nanoparticles (AgNPs) are used in 25% of all nano-enabled products and applied for anti-microbial properties. Silver nanoparticles are discharged into aquatic environments through wastewater discharge, runoff, and chemical spills. Once in aquatic environments silver nanoparticles have the potential to harm aquatic organisms. While the fate of silver nanoparticles in lentic systems has been investigated, limited information is available for the fate of silver nanoparticles in flowing environments. The purpose of this study was to compare the fate of AgNPs following a one-time pulsed application simulating a chemical spill, or small repetitive applications simulating effluent discharge, in artificial stream communities …

Application Of The Misclassification Simulation Extrapolation (Mc-Simex) Procedure To Log-Logistic Accelerated Failure Time (Aft) Models In Survival Analysis, Varadan Sevilimedu

College of Graduate Studies: Theses & Dissertations

Survival analysis is the study of time to event outcomes. Accelerated Failure Time models (AFT) serve as a useful tool in survival analysis to study the time of occurrence of an event and its relation to the covariates of interest. The accuracy of estimation of parameters in a model depends upon the correct measurement of covariates. Considering that perfect measurement of covariates is highly unlikely, it is imperative that the performance of the existing bias-correction methods be analyzed in AFT models. However, certain areas of bias-correction in AFT models still remain unexplored. One of these unexplored areas, is a situation …

Relationship Between School Climate And Student Achievement, Gail H. Greenway

College of Graduate Studies: Theses & Dissertations

Increasingly public schools in the United States are finding that factors beyond curriculum and instruction impact student achievement. Much research has been conducted on the relationship between school climate and student achievement (Cohen, McCabe, Michelli, & Pickeral, 2009; Guo & Higgins-D’Alessandro, 2011). This study set out to determine if there was a correlation between school climate and student achievement in middle schools in the Central Savannah River Area Regional Educational Service Agency region in the state of Georgia. Findings from this quantitative study indicated that there is a statistically significant, positive relationship between school climate and student achievement in middle …

Energy Storage Management And Simulation For Nano-Grids, Shantu Ghose

College of Graduate Studies: Theses & Dissertations

Energy storage has been utilized in many forms and applications from a flashlight to the Space Shuttle. There is a worldwide effort to develop battery model with high energy level and power densities for a variety range of applications, including hybrid electric vehicles (HEV) and photovoltaic system (PV). To improve battery technology, understanding the battery modeling is very important. So, modeling the thermal behavior of a battery is a vital consideration before designing an effective thermal management system which will operate safely and prolong the lifespan of an energy storage system. The first part of this work focused on the …

The Effect Of Acute Pain On Executive Function, Jenna M. Morogiello

College of Graduate Studies: Theses & Dissertations

Background: Executive functions are high-level cognitive processes that allow a person to successfully engage in an independent and self-fulfilling life. Previous literature indicates that acute pain can affect executive function, which may be due to a limited amount of shared neural resources of the brain.

Objective: The purpose of this study was to determine if acute pain affects executive function in recreationally active individuals who sustain a musculoskeletal injury.

Methodology: Twenty-four participants who presented with acute pain due to a musculoskeletal injury underwent a neuropsychological battery within 72 hours of injury and within two weeks from the initial testing session. …

Combinatorics Of Compositions, Meghann M. Gibson

College of Graduate Studies: Theses & Dissertations

Integer compositions and related enumeration problems have been extensively studied. The cyclic analogues of such questions, however, have significantly fewer results. In this thesis, we follow the cyclic construction of Flajolet and Soria to obtain generating functions for cyclic compositions and n-color cyclic compositions with various restrictions. With these generating functions we present some statistics and asymptotic formulas for the number of compositions and parts in such compositions. Combinatorial explanations are also provided for many of the enumerative observations presented.

A Comprehensive Analysis On Eeg Signal Classification Using Advanced Computational Analysis, Kaushik Bhimraj

College of Graduate Studies: Theses & Dissertations

Electroencephalogram (EEG) has been used in a wide array of applications to study mental disorders. Due to its non-invasive and low-cost features, EEG has become a viable instrument in Brain-Computer Interfaces (BCI). These BCI systems integrate user's neural features with robotic machines to perform tasks. However, due to EEG signals being highly dynamic in nature, BCI systems are still unstable and prone to unanticipated noise interference. An important application of this technology is to help facilitate the lives of the tetraplegic through assimilating human brain impulses and converting them into mechanical motion. However, BCI systems are remarkably challenging to implement …

“I’M Not Good At Math”: Mathematical Illiteracy And Innummeracy In The United States, G. Wesley Rogers

College of Graduate Studies: Theses & Dissertations

Why do we view mathematics the way we do in the United States and how have these views created an environment where we consider mathematical illiteracy and innumeracy socially and culturally acceptable when a lack of this knowledge and ability can function to enslave, exploit, restrict, and oppress. Throughout this investigation, I have explored some of the possible reasons for why we view education, mathematics, and the learning of mathematics the way we do and the impact of these views on our motivation and desire to learn mathematics. Using my over 20 years of teaching experience and the review of …

A Quantum Astrochemical Perspective On The C-C3h Radical With Application To The Interstellar Medium, Matthew Bassett

College of Graduate Studies: Theses & Dissertations

The interstellar medium (ISM) has been an area of focus for astrochemists and quantum chemists for many years, with particular interest in the presence of interstellar molecules and the resulting chemical processes. The c-C3H radical has been detected in the ISM near the dark molecular cloud TMC-1. With the application of ab initio computational methods using coupled-cluster theory at the singles, doubles, and perturbative triples [CCSD(T)] level, highly accurate quartic force fields (QFFs) are constructed to define the electronic wavefunction for the inter nuclear Hamiltonian. The QFF is used to predict the equilibrium geometry and produce vibrational frequencies, rotational constants, …

Approaches Toward Novel 1,2,3-Triazole Sensors For The Detection Of Anions And Heavy Metal Cations, Richard D. Govan

College of Graduate Studies: Theses & Dissertations

Cations and anions play pivotal roles in biological and physiological processes, however an imbalance in concentration of any ion can be detrimental. Therefore, research into the selective recognition of anions and heavy metal cations has acquired much attention. One approach involves the use of chemosensors. Upon interaction with targeted analytes, chemosensors produce a distinct response, in some cases a fluorescent or colorimetric signal. The 1,2,3-triazole unit has much potential as a chemical sensor due to its unique photophysical properties. The specificity, selectivity, and signaling mechanism of triazole sensors can be tuned with conjugation in the motif and choice and placement …

My Life Is A Manifesto: From Rich, To Poor, To Teacher, Angela M. Pieniaszek

College of Graduate Studies: Theses & Dissertations

This inquiry travels through stages of my education and life in order to explore the following three questions: How do a teacher’s values and personal experiences translate into teaching lives and teaching acts? How do teachers and students live counterstories inside and outside of the classroom? How do class, gender and place impact teaching and learning? Building on the works of critical theorists, (Apple, 2004; Ayers, 2004; Delpit, 2006; Freire, 2005; hooks, 1994; Kincheloe, 2004; Kincheloe & Pinar, 1991; Kozol, 1992; Watkins, 2001,2004), autobiographical studies (He, 2003, 2010; Miller, 2005; Pinar, 1994; Schubert & Ayers; 1990) and memoirs (Angelou, 1993; …

Synthesis And Biological Activity Of Novel Tu100 Derivatives, Oladotun J. Alao

College of Graduate Studies: Theses & Dissertations

In an attempt to create more effective chemotherapeutic compounds, the naphthoquinone adduct, 12,13-dihydro-N-methyl-6,11,13-trioxo-5H-benzo[4,5]cyclohepta [1,2 b]naphthalen-5,12-imine (hereafter called TU100) was synthesized. Inspired by its unique and novel mechanism of action, a series of structural derivatives were synthesized to explore structure-activity relationships. The analogues exhibited different cytotoxicity profiles, revealing the indicated regions are involved in cell death induction. Furthermore, the analogues had dramatically different effects on cellular ATP production, suggesting different molecular targets. Synthesis, biological activity, and SAR study of these analogues will be revealed.

An Interactionist View Of African American Males In Educational Leadership, Samuel D. Dasher Jr

College of Graduate Studies: Theses & Dissertations

During the segregation era, African American males held positions of leadership in schools in African American communities. When schools were integrated as a result of Brown v. The Board of Education, the number of African American males in positions of educational leadership began a rapid decline. Even as the demographics of the United States have become much more diverse, the gap between African American male educational leaders and their white male counterparts remains significant. This study examines the perceptions of African American male K-12 educational leaders about their positions, why they chose to become educational leaders, and the paths they …

A Concise Introduction To Logic, Craig Delancey

Milne Open Textbooks

A Concise Introduction to Logic is an introduction to formal logic suitable for undergraduates taking a general education course in logic or critical thinking, and is accessible and useful to any interested in gaining a basic understanding of logic. This text takes the unique approach of teaching logic through intellectual history; the author uses examples from important and celebrated arguments in philosophy to illustrate logical principles. The text also includes a basic introduction to findings of advanced logic. As indicators of where the student could go next with logic, the book closes with an overview of advanced topics, such as …

How To Become Data Literate: The Basics For Educators, Marcia Gail Headley

Mid-Western Educational Researcher

Book Review

Digitized And Decoupled? Teacher Sensemaking Around Educational Technology In A Model 1:1 Program, Stacy Gherardi

Mid-Western Educational Researcher

This mixed-methods study utilized surveys and interviews to analyze teacher sensemaking in a widely acclaimed 1:1 laptop program in a predominantly low-income, predominantly Latino school district. Quantitative and qualitative measures found that teachers across the district used technology in similar ways and that technology strongly increased differentiated instruction, changed how students accessed knowledge, and had a positive impact on assessment practices; a negative relationship between technology and parent engagement was found. Teacher perceptions of the 1:1 program varied widely and were dependent on both personal and organizational factors. Findings suggested a sensemaking process in which teacher beliefs were often decoupled …

Sniffing Out The Secret Poison: Selection Bias In Educational Research, Daniel A. Showalter, Luke B. Mullet

Mid-Western Educational Researcher

Selection bias is a persistent, and often hidden, problem in educational research. It is the primary obstacle standing in between increasingly available large education datasets and the ability to make valid causal inferences to inform policymaking, research, and practice (Stuart, 2010). This article provides an accessible discussion on the importance of understanding selection bias in educational research. Although a general explanation on how to remove selection bias is beyond the scope of this article, the reader is guided through an example of this removal process. Specifically, a propensity score analysis is used on a nationally representative dataset to examine whether …

Romances With Schools: A Life Of Education, James F. Lane

Mid-Western Educational Researcher

Book Review

High-Fat Diet And Glucose And Albumin Circadian Rhythms' Chronodisruption In Rats, Rafael Bravo, Americo Chini, Lierni Ugartemendia, Lourdes Franco, Mónica Mesa, Ana B. Rodriguez, Javier Cubero, Carmen Barriga

Turkish Journal of Biology

Obesity is one of the most widespread nutritional diseases in developed societies and it is considered a cardiovascular disease risk factor. The aim of the present work was to evaluate how a high-fat diet may influence the chronobiology of glucose and albumin circadian rhythms. Eighty-four male common Wistar rats were separated into two groups: a control group (n = 42) and a group fed a high-fat diet (n = 42); both for the control and the obesity-induced group we stablished 7 subgroups (6 rats per subgroup) to take blood samples at 0000, 0200, 0400, 1000, 1400, 1800, and 2200 hours. …

A Noise Estimation Scheme For Blind Spectrum Sensing Using Emd, Amr Nasr

Master's Theses and Capstones

The scarcity of spectral resources in wireless communications, due to a fixed frequency allocation policy, is a strong limitation to the increasing demand for higher data rates. One solution is to use underutilized spectrum. Cognitive Radio (CR) technologies identify transmission opportunities in unused channels and avoid interfering with primary users. The key enabling technology is the Spectrum Sensing (SS). Different SS techniques exist, but techniques that do not require knowledge of the signals (non-coherent) are preferred. Noise estimation plays an essential role in enhancing the performance of non-coherent spectrum sensors such as energy detectors. In this thesis, we present an …

Molecular Dynamics Studies Of Biomimetic Membranes, Daniel Ryan Barden

Master's Theses and Capstones

We have explored the conformational dynamics of the peptide-appended pillar[5]arene (PAP) channel in lipid and block copolymer (BCP) membranes through the use of molecular dynamics (MD) simulations. The novel polymeric structures trans-1,4-polybutadiene (PB), trans-1,4-polyisoprene (PI), and poly-2-methyl-2-oxazoline (PMOXA) were created and parameterized. These structures were then used to build and simulate pure PB12PEO9, PB23 PEO16 , PI12 PEO9 , and PI23PEO16 synthetic BCP membranes. In addition, simulations of the PAP channel inserted into lipid (POPC), PB12 PEO9 , and PB23PEO16 membranes were conducted. Results of simulations containing PAP suggest that the membrane environment can affect the channel dynamics and potentially …

Evaluating The Use Of Unmanned Aerial Systems (Uas) For Collecting Thematic Mapping Accuracy Assessment Reference Data In New England Forest Communities, Benjamin Thomas Fraser

Master's Theses and Capstones

To overcome the main drivers of global environmental change, such as land use and land cover change, evolving technologies must be adopted to rapidly and accurately capture, process, analyze, and display a multitude of high resolution spatial variables. Remote sensing technologies continue to advance at an ever-increasing rate to meet end-user needs, now in the form of unmanned aerial systems (UAS or drones). UAS have bridged the gap left by satellite imagery, aerial photography, and even ground measurements in data collection potential for all matters of information. This new platform has already been deployed in many data collection scenarios, being …

Applications Of Machine Learning And Computer Vision For Smart Infrastructure Management In Civil Engineering, Shounak Mitra

Master's Theses and Capstones

Machine Learning and Computer Vision are the two technologies that have innovative applications in diverse fields, including engineering, medicines, agriculture, astronomy, sports, education etc. The idea of enabling machines to make human like decisions is not a recent one. It dates to the early 1900s when analogies were drawn out between neurons in a human brain and capability of a machine to function like humans. However, major advances in the specifics of this theory were not until 1950s when the first experiments were conducted to determine if machines can support artificial intelligence. As computation powers increased, in the form of …

The Paladin Suite: Multifaceted Characterization Of Whole Metagenome Shotgun Sequences, Anthony Stephen Westbrook

Master's Theses and Capstones

Whole metagenome shotgun sequencing is a powerful approach for assaying many aspects of microbial communities, including the functional and symbiotic potential of each contributing community member. The research community currently lacks tools that efficiently align DNA reads against protein references, the technique necessary for constructing functional profiles. This thesis details the creation of PALADIN – a novel modification of the Burrows-Wheeler Aligner that provides orders-of-magnitude improved efficiency by directly mapping in protein space. In addition to performance considerations, utilizing PALADIN and associated tools as the foundation of metagenomic pipelines also allows for novel characterization and downstream analysis.

The accuracy and …

Transparent Phased Patch Antenna Array For Beamsteering Applications, Cyle Ziegler

Master's Theses and Capstones

The ever expanding demand for wireless communications faces many challenges. As the necessity for wireless communications increases, inevitably, the impact wireless communications systems have on their environment will also increase. This is important because the environmental impact a communications system has may limit the locations in which that system can be deployed. For this reason, there is a demand for unobtrusive hardware in order to grow the wireless communications infrastructure. Furthermore, performance limiting factors associated with wireless communications can be mitigated by implementing steerable antennas, making a less obtrusive steerable antenna desired. The contribution of this work is the demonstration …

Critical Shear Stress Estimates For Sunken Alberta Bitumen In An Annular Flume, Ian P. Gaudreau

Master's Theses and Capstones

Under certain environmental conditions and depending on its specific gravity, spilled oil has the ability to sink to the bottom of a water body (e.g., lake, river, ocean) (i.e., sunken oil). Once there, it can be difficult to predict the sunken oil’s fate and transport, making response efforts challenging. The Office of Response and Restoration (ORR) of the National Oceanic and Atmospheric Administration (NOAA) currently uses mathematical models in an attempt to better predict the movement of spilled oil. However, mathematical models cannot be simulative of the predicted trajectory if the physical or chemical properties of the oil are unknown, …