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Association Of C-Reactive Protein With Bacterial And Respiratory Syncytial Virus-Associated Pneumonia Among Children Aged <5 Years In The Perch Study., Melissa M Higdon, Tham Le, Katherine L O'Brien, David R Murdoch, Christine Prosperi, Henry C Baggett, Daniel E Park, +Several Additional Authors

Epidemiology Faculty Publications

Background.

Lack of a gold standard for identifying bacterial and viral etiologies of pneumonia has limited evaluation of C-reactive protein (CRP) for identifying bacterial pneumonia. We evaluated the sensitivity and specificity of CRP for identifying bacterial vs respiratory syncytial virus (RSV) pneumonia in the Pneumonia Etiology Research for Child Health (PERCH) multicenter case-control study. Methods.

We measured serum CRP levels in cases with World Health Organization–defined severe or very severe pneumonia and a subset of community controls. We evaluated the sensitivity and specificity of elevated CRP for “confirmed” bacterial pneumonia (positive blood culture or positive lung aspirate or pleural fluid …

Standardization Of Clinical Assessment And Sample Collection Across All Perch Study Sites., Jane Crawley, Christine Prosperi, Henry C Baggett, W Abdullah Brooks, Maria Deloria Knoll, Daniel E Park, +Several Additional Authors

Epidemiology Faculty Publications

Background.: Variable adherence to standardized case definitions, clinical procedures, specimen collection techniques, and laboratory methods has complicated the interpretation of previous multicenter pneumonia etiology studies. To circumvent these problems, a program of clinical standardization was embedded in the Pneumonia Etiology Research for Child Health (PERCH) study.

Methods.: Between March 2011 and August 2013, standardized training on the PERCH case definition, clinical procedures, and collection of laboratory specimens was delivered to 331 clinical staff at 9 study sites in 7 countries (The Gambia, Kenya, Mali, South Africa, Zambia, Thailand, and Bangladesh), through 32 on-site courses and a training website. Staff competency …

The Diagnostic Utility Of Induced Sputum Microscopy And Culture In Childhood Pneumonia., David R Murdoch, Susan C Morpeth, Laura L Hammitt, Amanda J Driscoll, Nora L Watson, Daniel E Park, +Several Additional Authors

Epidemiology Faculty Publications

Background.

Sputum microscopy and culture are commonly used for diagnosing the cause of pneumonia in adults but are rarely performed in children due to difficulties in obtaining specimens. Induced sputum is occasionally used to investigate lower respiratory infections in children but has not been widely used in pneumonia etiology studies. Methods.

We evaluated the diagnostic utility of induced sputum microscopy and culture in patients enrolled in the Pneumonia Etiology Research for Child Health (PERCH) study, a large study of community-acquired pneumonia in children aged 1–59 months. Comparisons were made between induced sputum samples from hospitalized children with radiographically confirmed pneumonia …

Reduction Of Central Line Associated Bloodstream Infections In An Urban 40 Bed, Level Iii Neonatal Intensive Care Unit When New Practices Were Implemented, Roberta Glenn, Bsmt (Ascp) Cic

Department of Medicine Posters

BACKGROUND

• Central line-associated bloodstream infection (CLABSI) in the neonatal population is a major source of morbidity and mortality.
• The disruption of skin and mucus membranes by the use of invasive devices contributes to the susceptibility of this population.
• In our Neonatal Intensive Care Unit (NICU), the CLABSI rate was continually increasing.
• It became evident that new practice guidelines were necessary to reduce the CLABSI rate in this vulnerable population.

Poster presented at: APIC 2017 in Portland Oregon, United States.

Strategic Approach Of An Urban 900-Bed Academic Medical Center To Combat Clostridium Difficile Infection Transmission Using Staff Engagement, Courtney Mitchell, Mph, Kelly Zabriskie, Cic

Department of Medicine Posters

BACKGROUND

• Clostridium difficile infection (CDI) caused nearly 500,000 illnesses with 29,000 deaths in the United States
• Preventing hospital-associated Clostridium difficile infection (HA-CDI) is crucial to modern healthcare systems for reducing mortality, healthcare costs and length of stay
• There are multiple risk factors for CDI transmission in healthcare settings:
  • Failure to comply with hand hygiene
  • Ineffective equipment and surface cleaning
  • Diagnosis delays

Poster presented at: APIC 2017 in Portland Oregon, United States.

The New York City Childcare Influenza Vaccine Mandate: A Case Study, Amy E. Metroka

Dissertations and Theses

Background. In 2014, New York City (NYC) became the third jurisdiction in the United States (US) to enact a childcare influenza vaccine mandate, after the states of New Jersey and Connecticut. The mandate was enacted by the NYC Board of Health by amending the NYC Health Code. The mandate’s goal was to increase vaccination rates among 6-59-month-olds attending city-regulated public and private childcare programs, including prekindergarten, to protect children, families, and the community against influenza. Children younger than 5 years are at high risk for severe illness and complications from influenza. Children are also known to be a major source …

Factors Associated With Non-Acceptance Of Testing And Evaluation Of Household Contacts Exposed To Tuberculosis, Elvy G. Barroso

International Nursing Research Congress (INRC)

Purpose: The WHO reports that the incidence of TB is approximately 9.0 million new cases globally each year and approximately 3.3 million cases are missed by health systems as either undiagnosed or not reported. A single index case can infect up to 10 to 15 contacts over the course of a year. Thus, complete and timely evaluation of all contacts exposed to TB is crucial for decreasing the transmission and incidence of TB. Several barriers to testing of contacts have been identified, however, no studies specifically address contacts" non-acceptance to TB testing and evaluation. Both nurses and non-nurse managers conduct …

The Logic Of Uncertainty And Executive Discretion In Decision Making: The Dallas-Fort Worth Metroplex Ebola Response, Abraham David Benavides, Laura M. Keyes 5457315, David Mcentire, Erin K. Carlson

Journal of Public Management & Social Policy

This paper addresses an important question: what can a highly complex public health situation such as the Dallas-Fort Worth Ebola outbreak tell us about the use of discretion by executive level public administrators? The public administration literature is rich with evidence of street-level bureaucratic discretion, but has not explored executive level discretion decision making. The authors argue that in highly complex situations of uncertainty, such as in the case of the Dallas-Fort Worth regional Ebola emergency response, the executive use of discretion translates to decisions under the conditions of uncertainty. This article theorizes a logic of uncertainty when two important …

Emerging Antimicrobial Resistance In Early And Late-Onset Neonatal Sepsis, Lamiaa Mohnsen, Nermin Ramy, Dalia Saied, Dina Akmal, Niveen Salama, Mona Abdel Haleim, Hany Aly

Pediatrics Faculty Publications

Background

Compared to developed countries, the use of antimicrobials in Egypt is less regulated and is available over the counter without the need for prescriptions. The impact of such policy on antimicrobial resistance has not been studied. This study aimed to determine the prevalence of early and late onset sepsis, and the frequency of antimicrobial resistance in a major referral neonatal intensive care unit (NICU).

Methods

The study included all neonates admitted to the NICU over a 12-month period. Prospectively collected clinical and laboratory data were retrieved, including blood cultures and endotracheal aspirate cultures if performed.

Results

A total of …

Donor Microbes Persist Up To Two Years After A Fecal Transplant To Treat Recurrent C. Difficile Infection, Jeff Hansen

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No abstract provided.

Donor Microbes Persist Up To Two Years After A Fecal Transplant To Treat Recurrent C. Difficile Infection, Jeff Hansen

Browse All News

No abstract provided.

Innovative Use Of Electronic Tablets For Newly Diagnosed Cancer Patient Education, Patricia L. Cameron

International Nursing Research Congress (INRC)

The purpose of this study was to determine whether using an electronic tablet to provide coaching for flushing to cancer patients could minimize infection and occlusion complications that often occur when patients/caregivers are responsible for maintaining their PICC lines.

Water Safety And Aquatic Recreation Among International Tourists In New Zealand, Kevin Moran Ph.D., Duncan Ferner

International Journal of Aquatic Research and Education

Little is known about the water safety knowledge, attitudes, and behaviors of international tourists holidaying in New Zealand. An online survey was conducted among New Zealand residents (n = 413) and international tourists (n =181) in August 2015. Significantly more New Zealand residents (69%) than tourists (40%) reported swimming at a beach. Tourists were more likely to hold unsafe beliefs related to swimming and boating activity. More tourists agreed that they would swim at a non-patrolled beach. Both residents and visitors had a poor understanding of rip currents at surf beaches. Ways of promoting water safety messaging to …

What's Happening: June 12, 2017, Maine Medical Center

What's Happening

No abstract provided.

Identification Of Antigenic Sarcoptes Scabiei Proteins For Use In A Diagnostic Test And Of Non-Antigenic Proteins That May Be Immunomodulatory, Majorie S. Morgan, S. Dean Rider, Larry G. Arlian

Biological Sciences Faculty Publications

Background

Scabies, caused by the mite, Sarcoptes scabiei, infects millions of humans, and many wild and domestic mammals. Scabies mites burrow in the lower stratum corneum of the epidermis of the skin and are the source of substances that are antigenic or modulate aspects of the protective response of the host. Ordinary scabies is a difficult disease to diagnose.

Objective

The goal of this project was to identify S. scabiei proteins that may be candidate antigens for use in a diagnostic test or may be used by the mite to modulate the host’s protective response.

Methods

An aqueous …

Risk Of Forgetting Medical Miracles: Measles Outbreak, Alicia Rohan

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No abstract provided.

New Faculty Fellowship To Expand Undergraduate Research Opportunities, Haley Herfurth

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No abstract provided.

Resiliency, Generalized Self-Efficacy And Mindfulness As Moderators Of The Relationship Between Stress And Both Life Satisfaction And Depression Among College Students: An Investigation Of The Resilience Process, Ben N. Smith Iv

Electronic Theses and Dissertations Archive

This dissertation attempted to add to the resilience literature by answering two research questions. The first was:"does resiliency serve as a unique protective factor compared to generalized self-efficacy (GSE) and mindfulness?" It was hypothesized that (1a) GSE, mindfulness and resiliency at time 1 would all uniquely predict lower depression and higher life-satisfaction at time 2; (1b) resiliency would be a stronger predictor of these outcomes than mindfulness and GSE; and (2) resiliency would uniquely buffer the relationship between stress and both time 2 depression and life satisfaction. The second question was: "Is resiliency predicted by GSE and mindfulness, or, alternatively, …

A Unique Presentation Of An Intracranial Abscess Secondary To Retained Projectile After Debridement With Dural Closure., Jason Milton, Victor Awuor

Trauma and Acute Care Articles

Patients with penetrating head trauma with retained projectiles develop intracranial abscesses as a common complication. The most common presentation is a suddenly worsening headache. The most common pathogen identified is staphylococcus. Outcomes are related to adherence of Matson's tenets. This case study details the presentation of a 19-year-old patient that presented to the neurological surgery clinic without neurologic deficits. Further questioning revealed complaints of intermittent diffuse headaches with bilateral upper extremity shock-like sensation for two weeks. Eight weeks prior he had undergone right craniotomy, after a gunshot wound, for debridement and watertight dural closure. The patient denied symptoms of fever, …

Neuroimaging And Cognitive Outcomes In Adults With Human Immunodeficiency Virus And Early Life Stress, Laurie M. Baker

Dissertations

Brain abnormalities persist in individuals with human immunodeficiency virus (HIV) despite the use of highly active antiretroviral therapy (HAART). To date, limited work has focused on the association between early life stress (ELS) and brain integrity in individuals with HIV, although ELS is highly prevalent in this population. The present study was conducted to determine whether ELS corresponds to the expression of persistent HIV–related neuroimaging abnormalities and cognitive dysfunction. A total of 130 HIV+ individuals on HAART and 76 HIV– individuals underwent 3T structural magnetic resonance imaging, diffusion tensor imaging, and neuropsychological assessment. Individuals were free of major psychiatric illness …

Gold Nanoparticles And Quantum Dots: Their Optical Interaction And Application In A Hydrogel Modified Lateral Flow Sensing Device, Julie A. Jenkins

Doctoral Dissertations

The goal of this dissertation was to study the optical properties of gold nanoparticles (Au NP) and quantum dots (QD) and to use their unique properties in sensing applications. The first part of this dissertation focuses on studying the dipole coupling in a gold nanoparticle random array. A blue shift and narrowing of the extinction peak, when compared to the single particle and solution spectra, was observed when 120 nm Au NPs were randomly immobilized on a glass substrate. This was determined to be due to the long-range dipole coupling of the Au NPs in the array. The motivation behind …

Rnaseq Analysis Of The Drosophila Response To The Entomopathogenic Nematode Steinernema., Shruti Yadav, Sean Daugherty, Amol Carl Shetty, Ioannis Eleftherianos

Computational Biology Institute

Drosophila melanogaster is an outstanding model to study the molecular and functional basis of host-pathogen interactions. Currently, our knowledge of microbial infections in D. melanogaster is well understood; however, the response of flies to nematode infections is still in its infancy. Here, we have used the potent parasitic nematode Steinernema carpocapsae, which lives in mutualism with its endosymbiotic bacteria Xenorhabdus nematophila, to examine the transcriptomic basis of the interaction between D. melanogaster and entomopathogenic nematodes. We have employed next-generation RNA sequencing (RNAseq) to investigate the transcriptomic profile of D. melanogaster larvae in response to infection by S. carpocapsae symbiotic (carrying …

Uab Alumni And Faculty Add Zest To Birmingham's Rising Food Scene, Staff

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No abstract provided.

Lessons Learned: Incorporating Global Health Patient Experiences Into A Bsn Curriculum, Kathryn Sridaromont, Wendy Renee Thal, Belinda Gallegos

International Nursing Research Congress (INRC)

The development and implementation of global health experiences in our concept-infused BSN curriculum is valued at an institutional, administrative, and curriculum level to foster interconnectedness, compassion, clinical judgement and future advancement of nursing research. The institutional mission supports providing high quality culturally diverse educational opportunities for students and faculty to improve the health of people (TTUHSC Strategic Plan, 2016). Due to administrative value and support of global health experiences, our school of nursing has global health faculty representatives who collaborate with course faculty throughout the curriculum to compare the objectives of the global health experience to semester course objectives to …

Record Number Of Um Pharmacy Students Matched With Residencies, Anna Herd

University of Mississippi News

New graduates will help improve patient care throughout Mississippi and across the country

Executive Committee & Cabinet Minutes June 2017, Uno Faculty Senate

Faculty Senate Minutes

These are the official minutes of the Faculty Senate Executive Council Meetings at the University of Nebraska - Omaha (UNO) for Academic year 2016-2017. Minutes are not posted until officially approved by the Executive Council at the following meeting. Minutes are archived yearly within the UNO Library Archives

Zika, Feminism, And The Failures Of Health Policy, Johanna Bond

Washington and Lee Law Review Online

The Zika epidemic caused serious concerns about fetal health throughout Latin America and some southern states in the United States. The prevailing governmental response throughout the region continues to emphasize two disease control factors: pregnancy delay and mosquito abatement. This essay argues that the current health policy approach of the World Health Organization, the Centers for Disease Control, and various national governments fails in three primary ways. First, the approach does not adequately consider the intersection of gender and poverty; thus, the current policy fails to respond to the needs of women living in poverty. Second, the health policy response …

Long-Read Sequencing Improves Assembly Of Trichinella Genomes 10-Fold, Revealing Substantial Synteny Between Lineages Diverged Over 7 Million Years, Peter C. Thompson, Dante S. Zarlenga, Ming-Yuan Liu, Benjamin M. Rosenthal

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Genome assemblies can form the basis of comparative analyses fostering insight into the evolutionary genetics of a para- site’s pathogenicity, host–pathogen interactions, environmental constraints and invasion biology; however, the length and complexity of many parasite genomes has hampered the development of well-resolved assemblies. In order to improve Trichinella genome assemblies, the genome of the sylvatic encapsulated species Trichinella murrelli was sequenced using third-generation, long-read technology and, using syntenic comparisons, scaffolded to a reference genome assembly of Trichinella spiralis, markedly improving both. A high-quality draft assembly for T. murrelli was achieved that totalled 63·2 Mbp, half of which was condensed into …

Development Of A Practice Change Model To Incorporate Tradition-Based Nursing Practices, Annette M. Bourgault, Michele J. Upvall

International Nursing Research Congress (INRC)

Purpose: The purpose of this study was to explore factors influencing the use of tradition-based practices and create a model of de-implementation processes to facilitate adoption of evidence-based practice in the critical care setting. This presentation is aligned with the conference objective of discussing research strategies to promote evidence-based teaching and learning influencing interprofessional environments.

Evidence-based practice is an expected standard of clinical practice as the means for optimizing patient outcomes and minimizing cost. Nursing research has focused its attention on the implementation of evidence-based practices without considering de-implementation of existing entrenched, routine practice, also known as tradition-based practice. Tradition-based …

Equity And Access To Health Care In Rural Quang Nam Province, Vietnam, Jessica Currier

Hatfield Graduate Journal of Public Affairs

This paper will addresses access to health care in rural Quang Nam Province in Vietnam. In doing so, it will examine the existing literature surrounding healthcare in Vietnam and compare it with the shortage of physicians in the study area and how that impacts who is able to receive care. The research presented in this paper synthesizes this analysis with interviews conducted by the author with policymakers and health care professionals in the study area. The paper concludes by offering policy recommendations that may rectify the healthcare issues that pervade the study area.