Digital Commons Network^™

Local Implementation Effectiveness Of A Multi-Tier System Of Support In Elementary School Settings, Terry P. Houlton

Student Work

Ensuring all students learn at high levels is demanding. Multi-tier systems of supports (MTSS) has shown promise as a way to promote high levels of learning for all students while catching students who are struggling to learn. However, implementing MTSS models in school districts and schools has seen its challenges. The context of an individual school impacts efforts related to implementation especially related to implementing a system such as MTSS. During the 2016-2017 school year, using program theory-driven evaluation methods a program theory for MTSS was developed with input from members of the research school district. Then a questionnaire was …

Impact Of Superstorm Sandy On Medicare Patients' Utilization Of Hospitals And Emergency Departments., Benoit Stryckman, Lauren Walsh, Brendan G. Carr, Nathaniel Hupert, Nicole Lurie

Department of Emergency Medicine Faculty Papers

INTRODUCTION: National health security requires that healthcare facilities be prepared to provide rapid, effective emergency and trauma care to all patients affected by a catastrophic event. We sought to quantify changes in healthcare utilization patterns for an at-risk Medicare population before, during, and after Superstorm Sandy's 2012 landfall in New Jersey (NJ).

METHODS: This study is a retrospective cohort study of Medicare beneficiaries impacted by Superstorm Sandy. We compared hospital emergency department (ED) and healthcare facility inpatient utilization in the weeks before and after Superstorm Sandy landfall using a 20% random sample of Medicare fee-for-service beneficiaries continuously enrolled in 2011 …

Bottom-Up Control Of Parasites, David S. Johnson, Richard W. Heard

Faculty Publications

Parasitism is a fundamental ecological interaction. Yet we understand relatively little about the ecological role of parasites compared to the role of free-living organisms. Bottom-up theory predicts that resource enhancement will increase the abundance and biomass of free-living organisms. Similarly, parasite abundance and biomass should increase in an ecosystem with resource enhancement. We tested this hypothesis in a landscape-level experiment in which salt marshes (60,000 m2 each) received elevated nutrient concentrations via flooding tidal waters for 11 yr to mimic eutrophication. Nutrient enrichment elevated the densities of the talitrid amphipod, Orchestia grillus, and the density and biomass of its trematode …

Evaluation Of Mothers And Infants With Presumed Exposure To Zika Virus: A Look Into The Lehigh Valley Experience, Tibisay Villalobos Md, Michelle Maron Rn, Jeanette Taveras Do

Department of Pediatrics

No abstract provided.

The Trophic Life Cycle Stage Of The Opportunistic Fungal Pathogen Pneumocystis Murina Hinders The Ability Of Dendritic Cells To Stimulate Cd4+ T Cell Responses, Heather M. Evans, Andrew Simpson, Shu Shen, Arnold J. Stromberg, Carol L. Pickett, Beth A. Garvy

Microbiology, Immunology, and Molecular Genetics Faculty Publications

The life cycle of the opportunistic fungal pathogen Pneumocystis murina consists of a trophic stage and an ascus-like cystic stage. Infection with the cyst stage induces proinflammatory immune responses, while trophic forms suppress the cytokine response to multiple pathogen-associated molecular patterns (PAMPs), including β-glucan. A targeted gene expression assay was used to evaluate the dendritic cell response following stimulation with trophic forms alone, with a normal mixture of trophic forms and cysts, or with β-glucan. We demonstrate that stimulation with trophic forms downregulated the expression of multiple genes normally associated with the response to infection, including genes encoding …

Group A Streptococcal Bacteraemia: Experience At King Fahad Medical City In Riyadh, Saudi Arabia, Fawzyh J. Al-Khadidi, Mohammed A. Alsheheri, Tariq S. Alfawaz, Mushira A. Enani, Abdulaziz A. Alaqeel, Dayel A. Alshahrani

Saudi Medical Journal

Objectives: To identify clinical presentation, predisposing factors, and the outcome in patients with Group A Streptococcal bacteremia. Methods: This is a retrospective study of 33 pediatric and adult patients with Streptococcus pyogenes bacteremia, admitted at King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia from 2007 to 2015. Results: Thirty-three patient records, documenting bacteremia with group A beta-hemolytic streptococcus, were reviewed. Approximately 51.5% were pediatric and 48.5% were adult patients, with a male to female ratio of 2:1. The most frequently reported complications were renal impairment (45.5%) and acute respiratory distress (21.2%), followed by localized infection (15.2%), pleural effusion (6.1%), …

Retrospective Cohort Study Of The Efficacy Of Azithromycin Vs. Doxycycline As Part Of Combination Therapy In Non-Intensive Care Unit Veterans Hospitalized With Community-Acquired Pneumonia, Justin Spivey, Heather Sirek, Robert Wood, Kalpit Devani, Billy Brooks, Jonathan Moorman

ETSU Faculty Works

The IDSA Community-Acquired Pneumonia (CAP) Guideline recommends ceftriaxone in combination with doxycycline as an alternative to combination therapy with ceftriaxone and azithromycin for non-intensive care unit (ICU) patients hospitalized with CAP. This is an attractive alternative regimen due to recent concerns of increased cardiovascular risk associated with azithromycin. The objective of this study was to compare the clinical outcomes of azithromycin and doxycycline each in combination with ceftriaxone for non-ICU Veterans hospitalized with CAP.

Responding To Infertility: Lessons From A Growing Body Of Research And Suggested Guidelines For Practice, Karina M. Shreffler, Arthur L. Greil, Julia Mcquillan

Department of Sociology: Faculty Publications

Infertility is a common, yet often misunderstood, experience. Infertility is an important topic for family scientists because of its effects on families; its relevance to research in related areas, such as fertility trends and reproductive health; and its implications for practitioners who work with individuals and couples experiencing infertility. In this review, we focus on common misperceptions in knowledge and treatment of infertility and highlight insights from recent research that includes men, couples, and people with infertility who are not in treatment. The meaning of parenthood, childlessness, awareness of a fertility problem, and access to resources are particularly relevant for …

Process Management And Design Layout Of High Throughput Screening, Anthony Vasquez, Kyle Dupuy

Industrial and Manufacturing Engineering

Calibr is a pharmaceutical company in San Diego and growing very quickly rate and need help redesigning their lab layout and in doing so reducing their cycle times and down times in machines. In addition to this, they do not currently have an accurate measurement of how long their processes take in an overall cycle. The objective of this project is to provide Calibr with a redesigned layout to accommodate new equipment as well as a software tool that can output Gantt charts for their planning of their testing. Our approach to this project first included mapping out the facilities …

University Of Washington Tele-Antimicrobial Stewardship Program (Uw-Tasp/Echo): Collaboration Across Washington State To Improve Antimicrobial Use, Yuan Zhou, John B. Lynch, Paul S. Pottinger, John Scott, Laura A.S Quilter, Maarisa D'Angeli, Zahra Kassamali, Rupali Jain, Robert J. Cybulski, Natalia Martinez-Paz

Project ECHO Bibliography

Background

The Centers for Disease Control and Prevention (CDC) have outlined core elements of effective antimicrobial stewardship programs (ASPs). However, many smaller community and “critical access hospitals” (CAHs) lack resources necessary to fully implement these programs. Tele-antimicrobial stewardship is highlighted in the Federal Register as a potential solution for such situations.

Methods

In January 2017 we implemented UW-TASP/ECHO, a remotely-based electronic answer to the problem of limited resources for ASPs at CAHs. This interdisciplinary collaboration involves infectious diseases (ID) faculty and fellows, ID pharmacists, and microbiologists from UW Medicine; epidemiologists from Washington State Department of Health (WA-DOH); program/technical support staff; …

Redefining Aging In Hiv Infection Using Phenotypes, David M. Stoff, Karl Goodkin, Dilip Jeste, Maria Marquine

ETSU Faculty Works

Purpose of review: This article critically reviews the utility of “phenotypes” as behavioral descriptors in aging/HIV research that inform biological underpinnings and treatment development. We adopt a phenotypic redefinition of aging conceptualized within a broader context of HIV infection and of aging. Phenotypes are defined as dimensions of behavior, closely related to fundamental mechanisms, and, thus, may be more informative than chronological age. Primary emphasis in this review is given to comorbid aging and cognitive aging, though other phenotypes (i.e., disability, frailty, accelerated aging, successful aging) are also discussed in relation to comorbid aging and cognitive aging. Recent findings: The …

Mechanism Of Action Of American Ginseng And Its Components In The Treatment Of Ulcerative Colitis, Anusha Chaparala

Theses and Dissertations

Inflammatory bowel diseases (IBD), mainly ulcerative colitis (UC), Crohn’s disease (CD), are chronic, idiopathic, inflammatory diseases of the gastrointestinal tract affecting millions of people worldwide. The incidence of IBD is steadily increasing in the modern world due to changes in dietary habits and other environmental influences that originated from industrialization. The etiology is poorly understood but is believed to be a combination of genetic predisposition, environmental factors, and overactive immune system. UC is characterized by inflammation and ulceration of colonic mucosa and rectum and has a higher incidence than CD. Aside from severely affecting the quality of life of the …

Diagnosis Of Mesenteric Panniculitis In The Multi-Detector Computed Tomography Era: Association With Malignancy And Surgical History, Waleed S. Mahafza, Karam A. Manzalawi, Azza A. Gharaibeh, Omar W. Khayat, Awni D. Shahait, Malik E. Juweid

Saudi Medical Journal

Objectives: To assess the prevalence and associations of mesenteric panniculitis (MP) using multi-detector CT (MDCT). Methods: This retrospective study included 4758 consecutive patients who underwent abdomino-pelvic MDCT between January 2012 and December 2014 at Jordan University Hospital, Amman, Jordan. Radiological database was searched for MP diagnosis and patients with suspected MP were re-evaluated by an experienced radiologist to confirm the diagnosis. Data on all patients with confirmed MP diagnosis were subsequently collected and analyzed. Results: Computed tomography features of MP were identified in 90 patients (41 males, 49 females), a prevalence of 1.9%. Mesenteric panniculitis was identified in both asymptomatic …

Assessing The Factor Structure Of The Childhood Trauma Questionnaire, And Cumulative Effect Of Abuse And Neglect On Mental Health Among Adolescents In Conflict-Affected Burundi, Ruby Charak, Jtvm De Jong, Lidewyde H. Berckmoes, Herman Ndayisaba, Ria Reis

Psychological Science Faculty Publications

The present study aimed to examine the factor structure of the Childhood Trauma Questionnaire (CTQ; Bernstein & Fink, 1998), highlight rates of abuse and neglect among Burundian adolescents, compare these rates with those found in high-income nations, and examine the cumulative effect of multiple types of abuse and neglect on depression and PTSD symptoms. Participants were 231 adolescents and youth (M = 14.9, SD = 1.99, 58.4% female) from five provinces of Burundi, a country in Central Africa affected by war and political violence. Translation and back-translation of the CTQ was carried out to obtain an adaptation of CTQ …

Medication Complications In Extracorporeal Membrane Oxygenation., Ami G. Shah, Michelle Peahota, Brandi Thoma, Walter K. Kraft

College of Pharmacy Faculty Papers

The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics. These changes can lead to exposure-driven decreases in efficacy or increased incidence of side effects. The pharmacokinetic changes are drug specific and largely undefined for most drugs. We review available drug dosing data and provide guidance for use in the ECMO patient population.

Bridging The Gap From Policy To Practice: Diabetes In Rural Morocco, Zoe H. Robbin

Independent Study Project (ISP) Collection

Morocco is in the midst of an epidemiologic transition ushered in by reduced fertility rates and extended life expectancy. Unlike two decades ago, today’s leading cause of death is chronic disease. In 2006, Moroccan officials launched Vision 2020, a comprehensive plan that seeks to expand access to healthcare and reign back the prevalence of noncommunicable disease, among other goals related to development. Through qualitative interviews with the residents of Tarmilat and Oulmes, a rural community south of Khamissat, this paper represents the first assessment of Vision 2020’s performance thus far to combat the spread of type 2 diabetes among rural …

The Latex Journey: A Narrative Approach To Exploring Condom Use, Stigma, And Education From The Perspective Of Women In Masxha, Kylie Yocum

Independent Study Project (ISP) Collection

Although the South African National Department of Health (NDOH) is spending increasing amounts of money on improving their HIV programs (including the rollout of new, scented condoms for their condom distribution program), the rates of condom use at last sexual encounter are declining. This inquiry focused on young women in the neighborhood of Masxha, Cato Manor, and their opinions surrounding how condoms are being used or misused, as well as the gender norms that perpetrate this (mis)use. This inquiry demonstrated the narratives of these young women on factors such as condom acquisition, gendered stigma, and condom education, including the Life …

A Comparative Study Of The Barriers To Hiv Self-Management Among Myanmar Migrant And Han Chinese Women In Yunnan, China, Anna Gaden

Independent Study Project (ISP) Collection

HIV has transitioned from high-risk populations to the general population through sexual transmission – now the primary mode of transmission in China – and is currently the biggest public health crisis in China. Those who are not directly involved with commercial sex work (CSW) or intravenous drug use (IDU) are now vulnerable to contraction. Han Chinese women, especially young women, are generally more vulnerable to transmission than their male counterparts, both physically and socially, and the virus affects their lives more deeply. Myanmar migrant women are even more vulnerable, as their migrant status leaves them without support structures or protections …

Essential Newborn Care During Humanitarian Crises: Integration Of Low-Cost Interventions, Athena Wong

Independent Study Project (ISP) Collection

Newborn healthcare has long been neglected on the international agenda despite neonatal death making up 44% of all under-five deaths. Neonates are newborns under 28 days of age and are the most vulnerable population with the highest risk of mortality during humanitarian emergencies. The common misconception that neonatal healthcare is very expensive and requires delivery from highly skilled healthcare professionals must be dismissed. There are many low-cost interventions that are highly effective at saving lives, the most notable ones being kangaroo mother care, bag and mask resuscitation, and basic immunizations. The leading causes of neonatal death are prematurity, intrapartum complications, …

The Normal Review, A Literary And Arts Publication, Fall 2017, The Normal Review

The Normal Review

No abstract provided.

When Feeling Good Feels "Wrong": Avoiding Hedonic Consumption When It Reflects Immoral Character, Stephanie C. Lin, Taly Reich, Tamar A. Kreps

Research Collection Lee Kong Chian School Of Business

In contrast to traditional mood repair motivations, we find that people desire to experience negative emotions in response to moral violations. Therefore, people avoid hedonic consumption after negatively valenced moral content, and feel uncomfortable when negatively valenced moral content is followed by hedonic frivolous content in social media contexts

Red Cell Genotyping Precision Medicine: A Conference Summary, Ga Denomme, Wq Anani, Nd Avent, G Bein, Et Al

School of Biomedical Sciences

This review summarizes the salient points of the symposium ‘Red Cell Genotyping 2015: Precision Medicine’ held on 10 September 2015 in the Masur Auditorium of the National Institutes of Health. The specific aims of this 6th annual symposium were to: (1) discuss how advances in molecular immunohematology are changing patient care; (2) exemplify patient care strategies by case reports (clinical vignettes); (3) review the basic molecular studies and their current implications in clinical practice; (4) identify red cell genotyping strategies to prevent alloimmunization; and (5) compare and contrast future options of red cell genotyping in precision transfusion medicine. This symposium …

Measuring Home Environments Across Cultures: Invariance Of The Home Scale Across Eight International Sites From The Mal-Ed Study, Paul C. Jones, Laura L. Pendergast, Barbara A. Schaefer, Muneera Rasheed, Erling Svensen, Rebecca Scharf, Rita Shrestha, Angelina Maphula, Reeba Roshan, Zeba Rasmussen

Department of Paediatrics and Child Health

The home environment provides the context for much of a child's early development. Examples of important aspects of the home environment include safety, cleanliness, and opportunities for cognitive stimulation. This study sought to examine the psychometric properties of an adapted form of the Home Observation for the Measurement of the Environment (HOME; Caldwell & Bradley, 1984, 2003) across the eight international sites of the MAL-ED project (Dhaka, Bangladesh; Vellore, India; Bhakatapur, Nepal; Naushahro Feroze, Pakistan; Fortaleza, Brazil; Loreto, Peru; Venda, South Africa; Haydom, Tanzania), to identify a factor structure that fit the data at all sites, and to derive a …

Global Respiratory Syncytial Virus-Associated Mortality In Young Children (Rsv Gold): A Retrospective Case Series, Nienke M. Scheltema, Angela Gentile, Florencia Lucion, D James Nokes, Patrick K. Munywoki, Shabir A. Madhi, Michelle J. Groome, Cheryl Cohen, Jocelyn Moyes, Syed Asad Ali

Department of Paediatrics and Child Health

Background: Respiratory syncytial virus (RSV) infection is an important cause of pneumonia mortality in young children. However, clinical data for fatal RSV infection are scarce. We aimed to identify clinical and socioeconomic characteristics of children aged younger than 5 years with RSV-related mortality using individual patient data.

Methods: In this retrospective case series, we developed an online questionnaire to obtain individual patient data for clinical and socioeconomic characteristics of children aged younger than 5 years who died with community-acquired RSV infection between Jan 1, 1995, and Oct 31, 2015, through leading research groups for child pneumonia identified through a comprehensive …

Microbiology For Allied Health Students, Molly Smith, Sara Selby

Biological Sciences Open Textbooks

This open textbook is a remix of Openstax Microbiology, CC-BY 4.0, and created through an Affordable Learning Georgia Round Six Textbook Transformation Grant.

The textbook has the following supplemental materials within this repository:

This is a collection of instructional materials for the following open textbook and lab manual:

• Microbiology for Allied Health Students Lab Manual
• Microbiology for Allied Health Students Instructional Materials

Authors' Description:

Microbiology for Allied Health Students is designed to cover the scope and sequence requirements for the single semester Microbiology course for non-majors and allied health students. The book presents the core concepts of microbiology …

Needle Acquisition Patterns, Network Risk And Social Capital Among Rural Pwid In Puerto Rico, Ian Duncan, Patrick Habecker, Roberto Abadie, Ric Curtis, Bilal Khan, Kirk Dombrowski

Department of Sociology: Faculty Publications

Background: People who inject drugs (PWID) take on significant risks of contracting blood-borne infection, including injecting with a large number of partners and acquiring needles from unsafe sources. When combined, risk of infection can be magnified.

Methods: Using a sample of PWID in rural Puerto Rico, we model the relationship between a subject’s number of injection partners and the likelihood of having used an unsafe source of injection syringes. Data collection with 315 current injectors identified six sources of needles.

Results: Of the six possible sources, only acquisition from a seller (paid or free), or using syringes found on the …

Epid 7233 - Public Health Surveillance Methods, Jian Zhang

College of Public Health: Faculty Syllabi (2014-2021)

This course will provide students with a strong foundation in public health surveillance of both health conditions and risk factors. The course will teach the theory and practice of surveillance supported by many examples of surveillance systems from the developed and developing world. The class will build on and reinforce basic epidemiologic concepts. Students will be given the opportunity to design and evaluate a surveillance system.

Epid 7135a - Epidemiology Of Infectious Disease, Isaac Chun-Hai Fung

College of Public Health: Faculty Syllabi (2014-2021)

This course is designed to provide students with an overview of the principles and practices of infectious diseases epidemiology with focus on how the presence and control of communicable diseases affects public health locally, nationally and internationally. Topics to be covered include: 1) general principles of infectious diseases epidemiology, including outbreak investigation, surveillance, analysis of infectious diseases data, and laboratory testing of specimens; 2) major modes of infectious disease transmission, including airborne, food and water, zoonotic, insect vector, blood, and sexual transmission; 3) different control strategies for infectious diseases, including infection control, antimicrobial management, immunization, risk factor modification, and screening; …

Primary Hepatic Leiomyosarcoma Presenting As A Budd-Chiari-Like Syndrome., Jessica Watson, Carolyn Hanna Md, Ross Biggs Do, Matthew Sullivan

Department of Medicine

No abstract provided.

A Rare Presentation Of Hsv Type 2 Hepatitis., Jahangir Khan Md, Anam Malik Md, Sandhya Venkataraman Do, Hina A. Sheikh, Amy Slenker Md

Department of Medicine

No abstract provided.