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2017

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Is Every Tweet Created Equal? A Framework To Identify Relevant Tweets For Business Research, Thad Chee Oct 2017

Is Every Tweet Created Equal? A Framework To Identify Relevant Tweets For Business Research, Thad Chee

Information Technology & Decision Sciences Theses & Dissertations

It is a life or death matter for a firm to observe its environment and identify new threats or opportunities quickly. Information technology has increased firm’s speed and agility in responding to environmental changes. Social media offers a vast and timely source of environmental information that firms can readily use gauge public sentiment. Twitter is a high-speed service that allows anyone to “tweet” a message to any interested parties. Firms can access near instantaneous changes in the public mood about any topic by using Sentiment Analysis. These topics range from predicting equities prices to predicting election outcomes. A gap exists …


A Beginner's Guide To Local Meat Processing, Lauren Gwin, Kathryn Quanbeck Oct 2017

A Beginner's Guide To Local Meat Processing, Lauren Gwin, Kathryn Quanbeck

Journal of Extension

This article describes the Beginner's Guide to Local Meat Processing—a tool created by the national Niche Meat Processor Assistance Network (NMPAN) as an introduction to a complex topic. Increased consumer and producer interest in local meat and poultry has resulted in requests for Cooperative Extension, public agencies, economic development districts, nonprofit organizations, and other support organizations to participate in or lead efforts to build, expand, or enhance local processing. The guide, backed by NMPAN, is intended to improve the effectiveness of such efforts by providing a window on the complex economic, regulatory, operational, and market conditions and context in which …


Perceptions Of Crop Consultants And Crop Producers On Grazing Corn Residue In Nebraska, Jordan L. Cox-O'Neill, Kristen M. Ulmer, Manbir Rakkar, Lisa Franzen-Castle, Humberto Blanco-Canqui, Mary E. Drewnoski, James C. Macdonald, Richard J. Rasby Oct 2017

Perceptions Of Crop Consultants And Crop Producers On Grazing Corn Residue In Nebraska, Jordan L. Cox-O'Neill, Kristen M. Ulmer, Manbir Rakkar, Lisa Franzen-Castle, Humberto Blanco-Canqui, Mary E. Drewnoski, James C. Macdonald, Richard J. Rasby

Journal of Extension

We conducted a survey to evaluate factors influencing consultant recommendations on grazing and producer grazing practices in Nebraska. Producers who did not graze cited soil compaction, inconvenience (lack of watering and fencing), and lack of access to livestock as major reasons for not grazing. Producers who allowed grazing and consultants who recommended grazing were more likely than those who did not favor grazing to perceive that grazing increased subsequent grain yields. Most consultants and producers reported making decisions on the basis of their personal observations. Findings from the survey can be used for enhanced Extension dissemination and research activities regarding …


Using Gamification To Teach Livestock Management Skills, Ryan Reuter Oct 2017

Using Gamification To Teach Livestock Management Skills, Ryan Reuter

Journal of Extension

This article describes a game that is based around estimating body weights of live cows and is used for teaching ranchers about the importance of monitoring the body weights of their animals. Ranchers viewed four cows and then used their smartphones to submit an estimate of each cow's weight. Results were accumulated and analyzed through use of a custom software script and then were shared with the ranchers during a training session. Following training, the ranchers evaluated four additional cows. Participating in and engaging with the game and training significantly improved ranchers' skill at estimating weight. Gamification can be a …


Straight From The Horse(Man)'S Mouth: Innovative 4-H Camps, Fawn Kurtzo, Leslie D. Edgar, Donna L. Graham, Mark Russell Oct 2017

Straight From The Horse(Man)'S Mouth: Innovative 4-H Camps, Fawn Kurtzo, Leslie D. Edgar, Donna L. Graham, Mark Russell

Journal of Extension

As 4-H evolves to include a wide breadth of youths' modern interests, innovative educational opportunities and evaluation practices become necessary. Horsemanship and safety-based horse camps were created in response to a statewide challenge to develop competitive 4-H members and retain those members as they approach adolescence. This article addresses the development, implementation, and review of Arkansas's horse 4-H camps. The article content includes a practical example of Kirkpatrick's evaluation model and a description of how a goal-based evaluation led to planned program modifications.


Usefulness Of Delivery Methods For Climate Change Programming: Perspectives Of Extension And Research Faculty, Kaila Thorn, Daniel Tobin, Rama Radhakrishna, Allison Chatchyan, Joana Chan, Shorna Allred Oct 2017

Usefulness Of Delivery Methods For Climate Change Programming: Perspectives Of Extension And Research Faculty, Kaila Thorn, Daniel Tobin, Rama Radhakrishna, Allison Chatchyan, Joana Chan, Shorna Allred

Journal of Extension

Extension is responding to climate change through programming intended to encourage adaptation and mitigation in agricultural production and natural resources management. However, effectively engaging target audiences requires identifying appropriate delivery methods. We conducted a study to identify delivery methods researchers and Extension professionals at land-grant universities in the northeastern United States perceive as useful for climate change outreach. Respondents viewed all delivery methods as only slightly useful, though traditional options, including face-to-face interactions and the use of videos and websites, were perceived as slightly more useful than other delivery methods. Therefore, we in Extension must experiment with various delivery methods …


Chairs Of Excellence Annual Report 2017, Tennessee. Higher Education Commission. Oct 2017

Chairs Of Excellence Annual Report 2017, Tennessee. Higher Education Commission.

Academic Programs and Workforce Reports

No abstract provided.


Vol 62 #5, Melanie Argo Oct 2017

Vol 62 #5, Melanie Argo

MPLA Newsletter

No abstract provided.


Social Norms, Heinrich Popitz Oct 2017

Social Norms, Heinrich Popitz

Genocide Studies and Prevention: An International Journal

No abstract provided.


Full Issue 11.2 Oct 2017

Full Issue 11.2

Genocide Studies and Prevention: An International Journal

No abstract provided.


Phase 1b Trial Of Proteasome Inhibitor Carfilzomib With Irinotecan In Lung Cancer And Other Irinotecan-Sensitive Malignancies That Have Progressed On Prior Therapy (Onyx Ist Reference Number: Car-Ist-553), Susanne M. Arnold, Kari Chansky, Markos Leggas, Michael A. Thompson, John L. Villano, John Hamm, Rachel E. Sanborn, Glen J. Weiss, Gurkamal Chatta, Maria Q. Baggstrom Oct 2017

Phase 1b Trial Of Proteasome Inhibitor Carfilzomib With Irinotecan In Lung Cancer And Other Irinotecan-Sensitive Malignancies That Have Progressed On Prior Therapy (Onyx Ist Reference Number: Car-Ist-553), Susanne M. Arnold, Kari Chansky, Markos Leggas, Michael A. Thompson, John L. Villano, John Hamm, Rachel E. Sanborn, Glen J. Weiss, Gurkamal Chatta, Maria Q. Baggstrom

Markey Cancer Center Faculty Publications

Introduction Proteasome inhibition is an established therapy for many malignancies. Carfilzomib, a novel proteasome inhibitor, was combined with irinotecan to provide a synergistic approach in relapsed, irinotecan-sensitive cancers. Materials and Methods Patients with relapsed irinotecan-sensitive cancers received carfilzomib (Day 1, 2, 8, 9, 15, and 16) at three dose levels (20/27 mg/m2, 20/36 mg/m2 and 20/45 mg/m2/day) in combination with irinotecan (Days 1, 8 and 15) at 125 mg/m2/day. Key eligibility criteria included measurable disease, a Zubrod PS of 0 or 1, and acceptable organ function. Patients with stable asymptomatic brain metastases were eligible. Dose escalation utilized a standard 3 …


Hmgb1-Rage Pathway Drives Peroxynitrite Signaling-Induced Ibd-Like Inflammation In Murine Nonalcoholic Fatty Liver Disease, Varun Chandrashekaran, Ratanesh K. Seth, Diptadip Dattaroy, Firas Alhasson, Jacek Ziolenka, James Carson, Franklin G. Berger, Balaraman Kalyanaraman, Anna Mae Diehl, Saurabh Chatterjee Oct 2017

Hmgb1-Rage Pathway Drives Peroxynitrite Signaling-Induced Ibd-Like Inflammation In Murine Nonalcoholic Fatty Liver Disease, Varun Chandrashekaran, Ratanesh K. Seth, Diptadip Dattaroy, Firas Alhasson, Jacek Ziolenka, James Carson, Franklin G. Berger, Balaraman Kalyanaraman, Anna Mae Diehl, Saurabh Chatterjee

Faculty Publications

Recent clinical studies found a strong association of colonic inflammation and Inflammatory bowel disease (IBD)-like phenotype with NonAlcoholic Fatty liver Disease (NAFLD) yet the mechanisms remain unknown. The present study identifies high mobility group box 1 (HMGB1) as a key mediator of intestinal inflammation in NAFLD and outlines a detailed redox signaling mechanism for such a pathway. NAFLD mice showed liver damage and release of elevated HMGB1 in systemic circulation and increased intestinal tyrosine nitration that was dependent on NADPH oxidase. Intestines from NAFLD mice showed higher Toll like receptor 4 (TLR4) activation and proinflammatory cytokine release, an outcome strongly …


12+ Years An Ir Manager, Paul Royster Oct 2017

12+ Years An Ir Manager, Paul Royster

University of Nebraska-Lincoln Libraries: Presentations

Survey of the history of the UNL DigitalCommons institutional repository: background, mission, usage, contents, trends, popularity, segments by series type, relative performance, IR assets, voluntary participation, faculty trust, results vis-a-vis SSRN, ResearchGate & Academia.edu, allies, obstacles, complaints, collection vs. service, gatekeepers, inclusiveness, ease of participation, feedback, disorder, the joy of giving, supplemental files, watermarking, encryption, customizations, base expansion, alerts, tracking faculty productivity, student workers, "Putting lipstick on the post-prints," packaging, publishing, journals, monographs, opportunity, publisher propaganda, the future, asymmetric contests, Elsevier as T. rex, innovation, disruption, control, Borges on the unknowables, pie chart of the universe, the physics of information, …


An Unparalleled Opportunity For An Important Ecological Study, L. David Mech, Shannon M. Barber-Meyer, Juan Carlos Blanco, Luigi Boitani, Ludwig Carbyn, Glenn Delgiudice, Steven H. Fritts, Djuro Huber, Olof Liberg, Brent Patterson, Richard R. Thiel Oct 2017

An Unparalleled Opportunity For An Important Ecological Study, L. David Mech, Shannon M. Barber-Meyer, Juan Carlos Blanco, Luigi Boitani, Ludwig Carbyn, Glenn Delgiudice, Steven H. Fritts, Djuro Huber, Olof Liberg, Brent Patterson, Richard R. Thiel

United States Geological Survey, Northern Prairie Wildlife Research Center: Publications

Wolves (Canis lupus) and moose (Alces americanus) have been studied since 1958 on 540-squarekilometer Isle Royale National Park, in Lake Superior. Wolves arrived there across the ice around 1949, and the population once increased to about 50, averaging about 25 annually (Mech 1966, Jordan et al. 1967, Vucetich and Peterson 2009). However, for various reasons, wolf numbers there have now dwindled to 2 nonbreeders, and the US National Park Service has proposed reintroducing 20–30 wolves over 3 years (National Park Service 2016). This situation offers an unparalleled opportunity to promote science-based management of this unique national park. …


Is Cooperative Memory Special? The Role Of Costly Errors, Context, And Social Network Size When Remembering Cooperative Actions, Jeffrey R. Stevens, Tim Winke Oct 2017

Is Cooperative Memory Special? The Role Of Costly Errors, Context, And Social Network Size When Remembering Cooperative Actions, Jeffrey R. Stevens, Tim Winke

Jeffrey Stevens Publications

Theoretical studies of cooperative behavior have focused on decision strategies, such as tit-for-tat, that depend on remembering a partner’s last choices. Yet, an empirical study by Stevens et al. (2011) demonstrated that human memory may not meet the requirements that needed to use these strategies. When asked to recall the previous behavior of simulated partners in a cooperative memory task, participants performed poorly, making errors in 10–24% of the trials. However, we do not know the extent to which this task taps specialized cognition for cooperation. It may be possible to engage participants in more cooperative, strategic thinking, which may …


Use Of Lipid Emulsion Therapy In Local Anesthetic Overdose, Ozgur Karcioglu Oct 2017

Use Of Lipid Emulsion Therapy In Local Anesthetic Overdose, Ozgur Karcioglu

Saudi Medical Journal

The use of intravenous lipid emulsion (ILE) therapy as antidote in systemic toxicity of certain agents has gained widespread support. There are increasing data suggesting use of ILE in reversing from local anesthetic-induced systemic toxicity severe, life-threatening cardiotoxicity, although findings are contradictory. Efficiency of ILE was demonstrated in animal studies in the treatment of severe impairment of cardiac functions, via a mechanism for trapping lipophilic drugs in an expanded plasma lipid compartment (“lipid sink”). In patients with hemodynamic compromise and/or cardiovascular collapse due to lipid-soluble agents, ILE may be considered for resuscitation in the acute setting by emergency physicians. The …


Wound Infiltration With Bupivacaine 0.5% With Or Without Adrenaline Does Not Decrease Pain After Thyroidectomy: A Randomized Controlled Study, Ayman A. Mismar, Mohammad I. Mahseeri, Mutasim A. Al-Ghazawi, Firas W. Obeidat, Mai N. Albsoul, Mohammad S. Al-Qudah, Nader M. Albsoul Oct 2017

Wound Infiltration With Bupivacaine 0.5% With Or Without Adrenaline Does Not Decrease Pain After Thyroidectomy: A Randomized Controlled Study, Ayman A. Mismar, Mohammad I. Mahseeri, Mutasim A. Al-Ghazawi, Firas W. Obeidat, Mai N. Albsoul, Mohammad S. Al-Qudah, Nader M. Albsoul

Saudi Medical Journal

Objectives: To study the effect of local wound infiltration with and without adrenaline on pain perception after thyroidectomy using the visual analog score (VAS). Methods: A prospective randomized controlled double-blinded study was conducted between May 2015 and June 2016 at The University of Jordan Hospital, Amman, Jordan. Eighty-nine patients undergoing planned thyroidectomy were included in the study. Patients were divided randomly into 3 groups: Group A, local wound infiltration with bupivacaine 0.5% was administered; Group B, bupivacaine 0.5% with adrenaline was administered; Group C (control), no infiltration was performed. Standardized thyroidectomies were performed in the 3 groups. Pain perception was …


A Novel Method For Improving Chest Tube Insertion Skills Among Medical Interns: Using Biomaterial-Covered Mannequin, Ozgur Tatli, Suha Turkmen, Melih Imamoglu, Yunus Karaca, Mustafa Cicek, Metin Yadigaroglu, Selen T. Bayrak, Olgun Asik, Murat Topbas, Suleyman Turedi Oct 2017

A Novel Method For Improving Chest Tube Insertion Skills Among Medical Interns: Using Biomaterial-Covered Mannequin, Ozgur Tatli, Suha Turkmen, Melih Imamoglu, Yunus Karaca, Mustafa Cicek, Metin Yadigaroglu, Selen T. Bayrak, Olgun Asik, Murat Topbas, Suleyman Turedi

Saudi Medical Journal

Objectives: To develop a low-cost biomaterial-covered chest tube simulation model and assess its possible usefulness for developing the chest tube insertion skills among medical interns. Methods: This mannequin-based interventional study was performed in a University hospital setting. We included 63 physicians performing emergency medicine internship at the Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey, between January 2015 and March 2015. A dummy was prepared for training simulation using a display mannequin. Medical interns received instruction concerning pneumothorax and the chest tube procedure. A total of 63 medical interns participating in this interventional study were asked to insert a chest …


Evaluating Lethal And Nonlethal Management Options For Urban Coyotes, Stewart W. Breck, Sharon A. Poessel, Mary Ann Bonnell Oct 2017

Evaluating Lethal And Nonlethal Management Options For Urban Coyotes, Stewart W. Breck, Sharon A. Poessel, Mary Ann Bonnell

United States Department of Agriculture Wildlife Services: Staff Publications

Human–coyote (Canis latrans) conflict in urban environments is a growing issue in cities throughout the United States, with the primary problem being the development of problem individuals that are overly bold and aggressive with people and pets. Little research has focused on management options to deal with this conflict. We better define lethal and nonlethal management strategies associated with proactive and reactive management of coyotes with an emphasis on management of problem individuals. We then provide data from research in the Denver Metropolitan Area (DMA), Colorado, USA that focused on reactive lethal removal of problem coyotes and reactive …


Using Resident-Based Hazing Programs To Reduce Human–Coyote Conflicts In Urban Environments, Mary Ann Bonnell, Stewart W. Breck Oct 2017

Using Resident-Based Hazing Programs To Reduce Human–Coyote Conflicts In Urban Environments, Mary Ann Bonnell, Stewart W. Breck

United States Department of Agriculture Wildlife Services: Staff Publications

The concept of hazing (aversive conditioning) is often promoted as a tool for reducing human–coyote (Canis latrans) conflicts in urban environments. Little scientific evidence exists on the effectiveness of hazing, particularly hazing applied by residents (i.e., community-level hazing). Wildlife professionals question if residents will properly and consistently apply hazing techniques and if hazing impacts coyote behavior over short- and long-term periods. We describe 2 separate efforts designed to encourage residents to haze coyotes in the Denver Metro Area, Colorado, USA: a citizen science program and an open space hazing trial. Both efforts were intended to be management techniques …


Time-Efficient Hybrid Approach For Facial Expression Recognition, Roshni Velluva Puthanidam Oct 2017

Time-Efficient Hybrid Approach For Facial Expression Recognition, Roshni Velluva Puthanidam

Master's Projects

Facial expression recognition is an emerging research area for improving human and computer interaction. This research plays a significant role in the field of social communication, commercial enterprise, law enforcement, and other computer interactions. In this paper, we propose a time-efficient hybrid design for facial expression recognition, combining image pre-processing steps and different Convolutional Neural Network (CNN) structures providing better accuracy and greatly improved training time. We are predicting seven basic emotions of human faces: sadness, happiness, disgust, anger, fear, surprise and neutral. The model performs well regarding challenging facial expression recognition where the emotion expressed could be one of …


Developmental Lead And/Or Prenatal Stress Exposures Followed By Different Types Of Behavioral Experience Result In The Divergence Of Brain Epigenetic Profiles In A Sex, Brain Region, And Time-Dependent Manner: Implications For Neurotoxicology., Deborah A. Cory-Slechta, Marissa Sobolewski, Garima Varma, Jay S. Schneider Oct 2017

Developmental Lead And/Or Prenatal Stress Exposures Followed By Different Types Of Behavioral Experience Result In The Divergence Of Brain Epigenetic Profiles In A Sex, Brain Region, And Time-Dependent Manner: Implications For Neurotoxicology., Deborah A. Cory-Slechta, Marissa Sobolewski, Garima Varma, Jay S. Schneider

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Over a lifetime, early developmental exposures to neurocognitive risk factors, such as lead (Pb) exposures and prenatal stress (PS), will be followed by multiple varied behavioral experiences. Pb, PS and behavioral experience can each influence brain epigenetic profiles. Our recent studies show a greater level of complexity, however, as all three factors interact within each sex to generate differential adult variation in global post-translational histone modifications (PTHMs), which may result in fundamentally different consequences for life-long learning and behavioral function. We have reported that PTHM profiles differ by sex, brain region and time point of measurement following developmental exposures to …


Confronting The Ghost: Legal Strategies To Oust Medical Ghostwriters, Deanna Minasi Oct 2017

Confronting The Ghost: Legal Strategies To Oust Medical Ghostwriters, Deanna Minasi

Fordham Law Review

Articles published in medical journals contribute significantly to public health by disseminating medical information to physicians, thereby influencing prescribing practices. However, the information guiding treatment decisions becomes distorted by selective publishing and medical ghostwriting, which negatively affects overall patient care. Although there is general consensus in the medical community that these practices of publication bias represent a moral failing, the issue is rarely framed as a wrong that necessitates legal consequences. This Note takes the stance that medical ghostwriting constitutes an act prohibited under the Racketeer Influenced and Corrupt Organizations Act (RICO) and argues that physicians fraudulently named as authors …


Effect Of Bioglass Incorporation Into Electrochemically Aligned Collagen Threads On Mechanical Properties And Cell-Mediated Mineralization, Madhura Nijsure Oct 2017

Effect Of Bioglass Incorporation Into Electrochemically Aligned Collagen Threads On Mechanical Properties And Cell-Mediated Mineralization, Madhura Nijsure

Theses and Dissertations

Bone related diseases and disorders are a significant socioeconomic burden in the United States. Autografts and allografts are most commonly used for the treatment of bone defects and non-unions; however, they are associated with limitations such as donor site morbidity and immune rejection, respectively. Over the past few decades, bone tissue engineering (BTE) using scaffold and cells has garnered significant interest as an alternative method for the repair and regeneration of bone defects. Recreation of the tissue microenvironment via the development of biomimetic scaffolds that resemble the physicochemical aspects (i.e., composition, topography, stiffness) of native bone is a promising approach …


The Richness And Relative Abundance Of Small Mammals In Old Surface Coal-Mined Sites In Crawford And Cherokee Counties, Kansas, Fabio Giacomelli Oct 2017

The Richness And Relative Abundance Of Small Mammals In Old Surface Coal-Mined Sites In Crawford And Cherokee Counties, Kansas, Fabio Giacomelli

Electronic Theses & Dissertations

Species richness and relative abundance (RA) of the small terrestrial mammals were accessed in 20 different unreclaimed old coal mined sites in Crawford and Cherokee counties, southeast Kansas in 2014. Lines of Victor™ wooden snap-traps were set in three habitat types in each area: grassy, brushy and forested during 3-days period in each of the four seasons.

Southeast Kansas was heavily surface-mined (strip-mined) between the 1930’s and the 1970’s and many of these sites were not reclaimed (restored to the appearance of its original landscape). This has resulted in many types of altered habitats in this region such as strip-pits …


Cash Versus In-Kind Transfers: Comparative Differences And Individual Best Practices To Benefit Recipient Communities, Sarah Wicker Oct 2017

Cash Versus In-Kind Transfers: Comparative Differences And Individual Best Practices To Benefit Recipient Communities, Sarah Wicker

Senior Honors Theses

This research paper seeks to compare cash and in-kind transfers in the context of foreign poverty aid to determine which transfer style is most beneficial and to evaluate long-term best practices of each kind to more positively benefit the recipient communities. It does this by comparing arguments for and against each transfer model. The first argument discusses the differences in distribution costs between the two models. The second compares the cash transfer’s strong concept of choice with in-kind transfer’s typical style of controlled consumption of goods. The second argument discusses the timing and impact of targeting communities in connection to …


Food And Culture Fact Sheet: New Zealand, Une Applied Nutrition Program Oct 2017

Food And Culture Fact Sheet: New Zealand, Une Applied Nutrition Program

All Student-Created Educational Resources

A student-designed food and culture fact sheet.

This Fact Sheet is a brief and concise introduction and outline of the traditional cuisine and culture of New Zealand intended to be a resource for the nutrition community about these subjects. Topics include: traditional food, cultural practices and beliefs, food economics, and eating patterns.


Sifting Out The Past, Ken Albala Oct 2017

Sifting Out The Past, Ken Albala

College of the Pacific Faculty Articles

No abstract provided.


Identifying The Inflammatory Pathways Of Genes Upregulated In Ladmac Cells Exposed To Bcm7, Oumlissa Persaud, Mary Kusenda Oct 2017

Identifying The Inflammatory Pathways Of Genes Upregulated In Ladmac Cells Exposed To Bcm7, Oumlissa Persaud, Mary Kusenda

Biology & Chemistry Undergraduate Theses

Casein is the main protein present in milk and other dairy products. Beta-casein is one of the 3 major proteins in milk. Beta-casomorphin-9 (BCM9) was the original beta-casein protein found in milk, specifically cow's milk. However, a genetic mutation occurred and the 67th amino acid in the BCM9, proline, mutated to histidine (P67H) creating Beta-casamorphin-7 (BCM7). The protein BCM7 gets cleaved in the small intestine, making it readily absorbed in the body. In previous unpublished studies they found that murine leukocytes (LADMAC cells) showed an increase in inflammation when exposed to BCM7, as compared to BCM9. Therefore, the goal of …


Using Curcumin Nano-Lipid Particles In A Therapeutic Approach, Kayla Douglas, Angela Evans, Wei He, Mathew Coleman Oct 2017

Using Curcumin Nano-Lipid Particles In A Therapeutic Approach, Kayla Douglas, Angela Evans, Wei He, Mathew Coleman

STAR Program Research Presentations

Curcumin (Curcuma longa) is a plant-based polyphenol known to have several medicinal properties. Although several promising effects of using curcumin in clinical trials have been observed, its overall medicinal qualities are still limited due to low bioavailability. In order to increase the bioavailability, we are embedding curcumin within Nano-Lipid Particles (both curcumin telodendrimer discs and curcumin tNLPs). Telodendrimer nanolipoprotein particles (tNLPs) are discoidal self-assemblies containing lipids and apolipoproteins which can be used as a vehicle to carry proteins and other small molecules to the cell. Telodendrimer NLPs have been used to increase the bioavailability of drugs, and provide an ideal …