Digital Commons Network^™

Redefining Aging In Hiv Infection Using Phenotypes, David M. Stoff, Karl Goodkin, Dilip Jeste, Maria Marquine

ETSU Faculty Works

Purpose of review: This article critically reviews the utility of “phenotypes” as behavioral descriptors in aging/HIV research that inform biological underpinnings and treatment development. We adopt a phenotypic redefinition of aging conceptualized within a broader context of HIV infection and of aging. Phenotypes are defined as dimensions of behavior, closely related to fundamental mechanisms, and, thus, may be more informative than chronological age. Primary emphasis in this review is given to comorbid aging and cognitive aging, though other phenotypes (i.e., disability, frailty, accelerated aging, successful aging) are also discussed in relation to comorbid aging and cognitive aging. Recent findings: The …

From Désert To Patrie: Marguerite De Navarre’S Lessons From The New World, Carrie F. Klaus

Global Language Studies Faculty publications

The sixty-seventh novella in Marguerite de Navarre’s Heptaméron, the story of an unnamed woman cast off, with her traitorous husband, from Jean-François de La Rocque de Roberval’s colonizing expedition in 1542, has been called the oldest surviving literary text situated in what is now Canada. This article argues that Marguerite de Navarre seized upon this early modern Atlantic fait divers as an opportunity to propose expanded roles for women (in service to the King, in marriage, and in the Church), roles that could be worked out in the New World and brought back to the Old.

African Environmental Change From The Pleistocene To The Anthropocene, Colin Hoag, Jens-Christian Svenning

Anthropology: Faculty Publications

This review explores what past environmental change in Africa—and African people's response to it—can teach us about how to cope with life in the Anthropocene. Organized around four drivers of change—climate; agriculture and pastoralism; megafauna; and imperialism, colonialism, and capitalism (ICC)—our review zooms in on key regions and debates, including desertification; rangeland degradation; megafauna loss; and land grabbing. Multiscale climate change is a recurring theme in the continent's history, interacting with increasingly intense human activities from several million years onward, leading to oscillating, contingent environmental changes and societally adaptive responses. With high levels of poverty, fast population growth, and potentially …

Neighborhood Watch 2.0: Private Surveillance And The Internet Of Things, Daniel Healow

Washington Journal of Law, Technology & Arts

The use of low-cost cameras and internet-connected sensors is sharply increasing among local law enforcement, businesses, and average Americans. While the motives behind adopting these devices may differ, this trend means more data about the events on Earth is rapidly being collected and aggregated each day. Current and future products, such as drones and self-driving cars, contain cameras and other embedded sensors used by private individuals in public settings. To function, these devices must passively collect information about other individuals who have not given the express consent that is commonly required when one is actively using an online service, such …

Incommon- Fall 2017, Alumni Association Staff

InCommon

No abstract provided.

The Bandung Ethic And International Human Rights Praxis: Yesterday, Today And Tomorrow, Obiora C. Okafor

Articles & Book Chapters

Between April 18 and 24, 1955, a group of twenty-nine African and Asian states gathered in Bandung, Indonesia, for the very first Afro-Asian summit in recorded human history. Almost every single African and Asian state that was independent at the time was represented at Bandung. It is no wonder then that this moment is widely regarded in the literature as “the foundational moment of the Third World.” Issued on April 24, 1955, the Conference’s Final Communiqué captured what I refer to in this chapter as the Bandung ethic. This conference also inspired a long line of subsequent meetings of the …

Time Reversed Smoke Simulation, Jeremy Michael Oborn

Theses and Dissertations

Physics-based fluid simulation often produces unpredictable behavior that is difficult for artists to control. We present a new method for art directing smoke animation using time reversed simulation. Given a final fluid configuration, our method steps backward in time generating a sequence that, when played forward, is visually similar to traditional forward simulations. This will give artists better control by allowing them to start from any timestep of the simulation. We address a number of challenges associated with time reversal including generating a believable final configuration and reversing entropy.

Exploiting Conservation Lands: Can Hydrofracking Be Consistent With Conservation Easements?, Jessica Owley, Collin Doane

Journal Articles

No abstract provided.

Metabarcoding Analyses Of Gut Microbiome Compositions In Red Abalone (Haliotis Rufescens, Swainson, 1822) Fed Different Macroalgal Diets, Jinchen Guo

Capstone Projects and Master's Theses

Growth and gut microbiome composition of Red abalone, Haliotis rufescens, fed different diets were compared after six months. The diet treatments were starvation and three fresh macroalgal diets (Macrocystis pyrifera, Palmaria mollis, and Ulva lactuca). Abalone shell length and wet in-shell mass were measured for growth comparisons across treatments. Contents of the buccal cavity, intestine, and stomach, as well as seawater and macroalgal tissue samples, were also collected monthly for 16S rRNA Illumina MiSeq sequencing. Shell length and wet in-shell mass showed significant difference among treatments (two-way ANOVA test, F(2,74)=4.26, p=0.019) and months (two-way ANOVA …

Debugging Software Patents After Alice, Jonathan Stroud, Derek M. Kim

South Carolina Law Review

No abstract provided.

Gentlemen: The Right To Resist Unlawful Arrest In South Carolina, J. Christopher Clark

South Carolina Law Review

No abstract provided.

Effects Of Winter And Summer Thermal Variability Regimes On Growth And Metabolism In Brook Trout (Salvelinus Fontinalis), Spenser Chicoine

All NMU Master's Theses

Brook trout (Salvelinus fontinalis) is a cold-water species with a narrow range of thermal tolerance. Climate change projections show that in addition to increases in average temperatures worldwide, daily thermal variability is increasing. Such conditions could prove challenging for brook trout and other ectotherms that are adapted to small temperature ranges. This research investigates how the growth and metabolic capacities of brook trout respond to long-term exposure to thermal variation. Groups of fish were reared under three thermal regimes: constant baily temperature, a 4°C daily range, and an 8°C daily range in a controlled lab setting. This was …

Maximizing Use Of An Extension Beef Cattle Data Set: Part 3—Weights And Growth, Jennifer M. Ramsay, Lauren L. Hulsman Hanna, Kris A. Ringwall

Journal of Extension

Previously, we described calving distribution and reproductive rates from CHAPS20Y, an Extension beef cattle data set. In this article, we describe CHAPS20Y data on birth weight, weaning weight, pounds weaned per cow exposed, calf age at weaning/weighing, average daily gain, weight per day age, frame score, and cow age, weight, and condition. Yearly mean weights and growth are consistent over the 20-year period, with variation among herds. Breed, management, and environmental differences may explain some of the variation. Our analysis of the CHAPS20Y data provides Extension professionals with expanded knowledge of beef cattle weights and growth and, accordingly, improved ability …

Impact Of Electrospun Conduit Composition And Peritoneal Pre-Conditioning On Patency And Remodeling Of Tissue Engineered Vascular Grafts, Mozhgan Shojaee

Theses and Dissertations

Overall goal of this project was to develop a tissue engineered vascular graft by implanting an electrospun tubular conduit into the peritoneal cavity to recruit autologous cells to it and provide the cells with the components of the hysiological environment prior to grafting the conduit into the artery. This was accomplished through three complimentary studies: finding the best ratio of poly(ε-caprolactone) (PCL) and collagen that improves inflammatory response within the peritoneal cavity; determining the effect of peritoneal pre-implantation and the amount of incorporated collagen on graft functionality; and reducing the potential side effect of peritoneal adhesion formation. In the first …

Distributions Of Polychaetes As A Function Of Sediment Composition In A Subtropical Lagoon, Anthony William Cox

Theses and Dissertations

Fine-grained organic-rich sediments (FGORS) in the Indian River Lagoon (IRL), Florida, the human activities and nutrient inputs and have a varied composition, including water content, silt-clay content, and organic matter. When these constituents reach, by weight, 75%, 60% dry, and 10% dry, respectively, this is sometimes referred to as IRL “muck”. Many polychaetes inhabit the benthic sediments of estuaries and must tolerate various degrees of FGORS. The Cox IRL Muck Index (CMI) is proposed as a mechanism for determining the organic sediment tolerances of infaunal species in a simple and direct manner. IRL muck will have a minimum CMI of …

Muscle Coordination Contributes To Function After Stroke; Proprioception Contributes To Control Of Posture, Movement, Maria Bengtson

Dissertations (1934 -)

More than half of stroke survivors experience persistent upper extremity motor impairments that can negatively impact quality of life and independence. Effective use of the upper extremity requires coordination of agonist/antagonist muscle pairs, as well as coordination of multiple control actions for stabilizing and moving the arm. In this dissertation, I present three studies in which I recorded isometric torque production, single joint movement and stabilization, and clinical measures of function and impairments after stroke to evaluate the extent to which changes in coordination of agonist/antagonist muscles and of sequential control actions contribute to deficits after stroke. In Aim 1, …

Nucleotide-Dependent Preferential Localization Of Ras In Model Membranes With Lipid Raft Nanodomains, Anna Shishina

Dissertations (1934 -)

Membrane proteins constitute a third of all proteins in the cell and more than 50% of drug targets. However, the analysis of membrane proteins has many challenges owing to their partially hydrophobic surfaces, flexibility and lack of stability. One example of an essential membrane protein is Ras superfamily. Ras is a small monomeric GTPase involved in regulation of cell growth, proliferation and differentiation. Therefore, Ras and its effectors are among the most important targets for cancer therapy. A detailed knowledge of the processes occurring during signal propagation via Ras might help to elucidate the mechanisms of the involved signal cascades. …

Effects Of Livestock Grazing On Rangeland Biodiversity: A Meta-Analysis Of Grouse Populations, Seth J. Dettenmaier, Terry A. Messmer, Torre J. Hovick, David K. Dahlgren

Wildland Resources Faculty Publications

Livestock grazing affects over 60% of the world’s agricultural lands and can influence rangeland ecosystem services and the quantity and quality of wildlife habitat, resulting in changes in biodiversity. Concomitantly, livestock grazing has the potential to be detrimental to some wildlife species while benefiting other rangeland organisms. Many imperiled grouse species require rangeland landscapes that exhibit diverse vegetation structure and composition to complete their life cycle. However, because of declining populations and reduced distributions, grouse are increasingly becoming a worldwide conservation concern. Grouse, as a suite of upland gamebirds, are often considered an umbrella species for other wildlife and thus …

Tribal Sovereignty And Gaming: A Proposal To Amend The National Labor Relations Act, Regina Gerhardt

Cardozo Law Review

No abstract provided.

Signing Statements And Presidentializing Legislative History, John M. De Figueiredo, Edward H. Stiglitz

Cornell Law Faculty Publications

Presidents often attach statements to the bills they sign into law, purporting to celebrate, construe, or object to provisions in the statute. Though long a feature of U.S. lawmaking, the President has avowedly attempted to use these signing statements as tool of strategic influence over judicial decisionmaking since the 1980s—as a way of creating “presidential legislative history” to supplement and, at times, supplant the traditional congressional legislative history conventionally used by the courts to interpret statutes. In this Article, we examine a novel dataset of judicial opinion citations to presidential signing statements to conduct the most comprehensive empirical examination of …

Fall 2017, A Summer Of New Unh International Program, An Unbelizeable Experience!, Patricia A. Halpin

UNH International Educator Newsletter

No abstract provided.

Classified Information: The Newsletter Of The Lloyd Sealy Library, Lloyd Sealy Library, Cuny John Jay College Of Criminal Justice

Reports and Publications from John Jay College

Classified Information was a publication that informed the College about Library services, personnel, upcoming events, new technologies, and available resources.

2017 (Fall) Ensi Informer Magazine, Morehead State University. Engineering Sciences Department

ENSI Informer Magazine Archive

The ENSI Informer Magazine published in the fall of 2017.

Increased Habenular Connectivity In Opioid Users Is Associated With An Α5 Subunit Nicotinic Receptor Genetic Variant, Kaylah Curtis, Humsini Viswanath, Kenia M Velasquez, David L Molfese, Mark J Harding, Eduardo Aramayo, Philip R Baldwin, Elisa Ambrosi, Alok Madan, Michelle Patriquin, B Christopher Frueh, J Christopher Fowler, Thomas R Kosten, David A Nielsen, Ramiro Salas

Staff and Researcher Publications

Background and objectives: Opioid use disorder (OUD) is a chronic disorder with relapse based on both desire for reinforcement (craving) and avoidance of withdrawal. The aversive aspect of dependence and relapse has been associated with a small brain structure called the habenula, which expresses large numbers of both opioid and nicotinic receptors. Additionally, opioid withdrawal symptoms can be induced in opioid-treated rodents by blocking not only opioid, but also nicotinic receptors. This receptor co-localization and cross-induction of withdrawal therefore might lead to genetic variation in the nicotinic receptor influencing development of human opioid dependence through its impact on the aversive …

Inhibition Of Apoptosis Signal-Regulating Kinase 1 Alters The Wound Epidermis And Enhances Auricular Cartilage Regeneration., Qian-Shi Zhang, Deepa S. Kurpad, My G. Mahoney, Marla J. Steinbeck, Theresa A. Freeman

Department of Orthopaedic Surgery Faculty Papers

Why regeneration does not occur in mammals remains elusive. In lower vertebrates, epimorphic regeneration of the limb is directed by the wound epidermis, which controls blastema formation to promote regrowth of the appendage. Herein, we report that knockout (KO) or inhibition of Apoptosis Signal-regulated Kinase-1 (ASK1), also known as mitogen-activated protein kinase kinase kinase 5 (MAP3K5), after full thickness ear punch in mice prolongs keratinocyte activation within the wound epidermis and promotes regeneration of auricular cartilage. Histological analysis showed the ASK1 KO ears displayed enhanced protein markers associated with blastema formation, hole closure and regeneration of auricular cartilage. At seven …

The Prospects Of Zinc As A Structural Material For Biodegradable Implants—A Review Paper, Galit Katarivas Levy, Jeremy Goldman, Eli Aghion

Michigan Tech Publications, Part 1

In the last decade, iron and magnesium, both pure and alloyed, have been extensively studied as potential biodegradable metals for medical applications. However, broad experience with these material systems has uncovered critical limitations in terms of their suitability for clinical applications. Recently, zinc and zinc-based alloys have been proposed as new additions to the list of degradable metals and as promising alternatives to magnesium and iron. The main byproduct of zinc metal corrosion, Zn²⁺, is highly regulated within physiological systems and plays a critical role in numerous fundamental cellular processes. Zn²⁺ released from an implant may suppress …

Exploring The Relationship Between Media Influence And Policy Output: A State Comparative Study, Stephanie Savas Joannou Menefee

School of Public Service Theses & Dissertations

Through the years, various forms of media have become political institutions able to influence the public policy agenda. Analyzing policy helps to promote a better understanding of how the policy process works, how problems appear on the political agenda, and why governments choose to act or not to act on particular policy problems. This research utilizes Baumgartner and Jones’s (1993) Theory of Punctuated Equilibrium (PET) to examine the ways in which media attention influenced public policy on marijuana in the states of Kentucky, Massachusetts, and Vermont between 1996 and 2016.

Using qualitative research methods, the researcher conducted an exploratory, comparative …

Quantifying Pollutant Removal Rates Of Bioretention Basins As A Stormwater Best Management Practice, Evan Nathanial Waagen

Civil & Environmental Engineering Theses & Dissertations

Water pollution is an ongoing problem that can be attributed to human activities. As world population increases and countries become more developed, this problem intensifies. Fortunately, the causes and solutions of water pollution are documented and have been implemented with various levels of success. These solutions, or Best Management Practices (BMPs), vary in type and function and remove pollutants from runoff prior to it reaching rivers, lakes, and other bodies of water. This study investigates bioretention basins, a specific group of BMPs, and presents analysis and prediction of their performance, of which our knowledge is incomplete in the existing literature. …

An Interpretative Phenomenological Analysis Of The Lived Experiences And Mentoring Relationships Of Black Women Student Affairs Administrators, Tiffany Shawna Wiggins

Educational Leadership & Workforce Development Theses & Dissertations

Contemporary literature regarding the experiences of Black women in higher education administration is scarce, and that which does exist, often focuses on those who serve in teaching faculty roles, and/or fails to provide a holistic perspective on the lives of those who makeup this group. Utilizing an interpretative phenomenological analysis approach, this qualitative investigation explored the lives of Black women college administrators from their perspective. Grounded in the theoretical framework of Patricia Hill Collins’s Black Feminist Thought, this study aimed to uncover the lived experiences of Black women student affairs administrators as they relate to their professional demands and pursuits …

Holistic Approach In Microalgae Conversion To Bioproducts And Biofuels Through Flash Hydrolysis, Ali Teymouri

Civil & Environmental Engineering Theses & Dissertations

In recent years, the demand for renewable energy, mainly biomass has increased. The U.S. Energy Information Administration reported that more than 13.3% of the total energy production in the first seven months of 2017 was produced from a biomass source. Among all biomass resources, microalgae has brought a lot of attention due to their numerous advantages such as higher growth rate and productivity compared with the conventional energy crops, higher energy conversion efficiency by photosynthesis, and less water requirement than terrestrial crops. However, its development is far behind industrial production. Several research efforts across the globe have been concerned with …