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2017

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Development And Validation Of Triticum Phytobiological Method As An Alternative Procedure For Investigating In Vivo Acute Toxicity On Mice, Emil Ştefănescu, Aurelia N. Cristea, Cornel Chiriță, Octavian Olaru, Adriana Anghel, Mihaela Dinu Oct 2017

Development And Validation Of Triticum Phytobiological Method As An Alternative Procedure For Investigating In Vivo Acute Toxicity On Mice, Emil Ştefănescu, Aurelia N. Cristea, Cornel Chiriță, Octavian Olaru, Adriana Anghel, Mihaela Dinu

Journal of Mind and Medical Sciences

The goal of this study was to validate an alternative method for determining in vivo acute toxicity using vegetal material instead of laboratory animals, starting from the phytobiological method known also as the Triticum technique. We set out to demonstrate that vegetal cells have similar sensitivity to some toxic agents as animal cells, in which case a statistical correlation could be established. A series of new compounds synthesized by the Romanian National Institute for Chemical Pharmaceutical Research and Development as potential β3 adrenergic receptors agonists were tested for their acute toxicity using classic animal exposure models, before investigating possible anti-diabetic …

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Protective Role Of S-Adenosylmethionine Against Fructose-Induced Oxidative Damage In Obesity, Kameliya Zh Bratoeva, Mariya A. Radanova, Albena V. Merdzhanova, Ivan S. Donev Oct 2017

Protective Role Of S-Adenosylmethionine Against Fructose-Induced Oxidative Damage In Obesity, Kameliya Zh Bratoeva, Mariya A. Radanova, Albena V. Merdzhanova, Ivan S. Donev

Journal of Mind and Medical Sciences

Introduction. It has been shown that S-adenosylmethionine (S-AMe) stimulates glutathione synthesis and increases cell resistance to the cytotoxic action of free radicals and pro-inflammatory cytokines. The aim of this study was to determine the effect of S-adenosylmethionine on the oxidative stress in adipose tissue in a model of fructose-induced obesity. Methods. The study was performed on male Wistar rats divided into 3 groups: control, fructose fed (HFD) (35%, 16 weeks), and HFD + S-AMe (20 mg/kg). We examined the changes in the ratio of retroperitoneal adipose tissue weight / body weight; levels of reduced glutathione (GSH) and malondialdehyde (MDA) in …

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Experimental Pharmacological Research Regarding Some Newly Synthesized Benzamides On Central Nervous System Functions, Cornel Chiriță, Emil Ștefănescu, Cristina D. Marineci, Simona Negreș, Diana C. Nuță Oct 2017

Experimental Pharmacological Research Regarding Some Newly Synthesized Benzamides On Central Nervous System Functions, Cornel Chiriță, Emil Ștefănescu, Cristina D. Marineci, Simona Negreș, Diana C. Nuță

Journal of Mind and Medical Sciences

Three newly synthesized benzamides by the Department of Pharmaceutical Chemistry of the Faculty of pharmacy from the University of Medicine and Pharmacy „Carol Davila” Bucharest were tested in order to determine whether these new molecules have similar effects on the central nervous system as those already in therapeutic use belonging to the same chemical group, such as tiapride (neuroleptic) or lidocaine (local anaesthetic). Tests were carried out on NMRI mice which were given new compounds, conventionally named I5C, I14C, and II5C in a dose of 1/20 of the lethal dose 50% (LD50), as previously determined. They received this treatment daily …

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Therapeutic Drug Monitoring And Methods Of Quantitation For Carbamazepine, Cristian Tuchila, Daniela Luiza Baconi, Cristina Dinu Pirvu, Denisa O. Balalau, Ana Maria Vlasceanu, Miriana Stan, Cristian Balalau Oct 2017

Therapeutic Drug Monitoring And Methods Of Quantitation For Carbamazepine, Cristian Tuchila, Daniela Luiza Baconi, Cristina Dinu Pirvu, Denisa O. Balalau, Ana Maria Vlasceanu, Miriana Stan, Cristian Balalau

Journal of Mind and Medical Sciences

Carbamazepine is an early anticonvulsant still used today in the treatment of several forms of epilepsy. An active metabolite in the human body contributes to its pharmacological effect. Carbamazepine metabolism has high inter-individual variability, such that it is relatively difficult to establish a direct link between dose and concentration, or between concentration and pharmacological effect. Carbamazepine is thus a good candidate for therapeutic drug monitoring (TDM). Good UV specific absorbance and high plasmatic concentrations allow for the use of UV detection, which is often more accessible than other methods of detection. This paper presents several methods used for the detection …

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The Santa Clara, 2017-10-05, Santa Clara University Oct 2017

The Santa Clara, 2017-10-05, Santa Clara University

The Santa Clara

No abstract provided.

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Lanthorn, Vol. 52, No. 13, October 5, 2017, Grand Valley State University Oct 2017

Lanthorn, Vol. 52, No. 13, October 5, 2017, Grand Valley State University

Volume 52, July 10, 2017 - April 23, 2018

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

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Uncovering The Genetic Architecture Of Seed Weight And Size In Intermediate Wheatgrass Through Linkage And Association Mapping, Xiaofei Zhang, Steven R. Larson, Liangliang Gao, Soon Li Teh, Lee R. Dehaan, Max Fraser, Ahmad Sallam, Traci Kantarski, Katherine Frels, Jesse Poland, Donald Wyse, James A. Anderson Oct 2017

Uncovering The Genetic Architecture Of Seed Weight And Size In Intermediate Wheatgrass Through Linkage And Association Mapping, Xiaofei Zhang, Steven R. Larson, Liangliang Gao, Soon Li Teh, Lee R. Dehaan, Max Fraser, Ahmad Sallam, Traci Kantarski, Katherine Frels, Jesse Poland, Donald Wyse, James A. Anderson

Forage and Range Research Laboratory Publications

Intermediate wheatgrass [IWG; Thinopyrum intermedium (Host) Barkworth & D.R. Dewey subsp. intermedium] is being developed as a new perennial grain crop that has a large allohexaploid genome similar to that of wheat (Triticum aestivum L.). Breeding for increased seed weight is one of the primary goals for improving grain yield of IWG. As a new crop, however, the genetic architecture of seed weight and size has not been characterized, and selective breeding of IWG may be more intricate than wheat because of its self-incompatible mating system and perennial growth habit. Here, seed weight, seed area size, seed width, and seed …

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The Setonian, October 5, 2017, Seton Hall University Oct 2017

The Setonian, October 5, 2017, Seton Hall University

2017

No abstract provided.

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A Need For Bananas? Dietary Potassium Regulates Calcification Of Arteries, Jeff Hansen Oct 2017

A Need For Bananas? Dietary Potassium Regulates Calcification Of Arteries, Jeff Hansen

Browse All News

No abstract provided.

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Where Morality And The Law Coincide: How Legal Obligations Of Bystanders May Be Informed By The Social Teachings Of Pope Francis, Amelia J. Uelmen Oct 2017

Where Morality And The Law Coincide: How Legal Obligations Of Bystanders May Be Informed By The Social Teachings Of Pope Francis, Amelia J. Uelmen

Seattle University Law Review

Since the beginning of his pontificate, Pope Francis has offered to the world powerful signs of how we should aspire to treat each other as human beings, as brothers and sisters in the one human family. He has communicated his message and his teachings in myriad ways: through symbolic gestures; his presence and words at gatherings in our world’s most troubled places; brief messages, homilies and meditations; and official documents that continue the application of the principles of Catholic social teaching to contemporary social questions. What might these prophetic signs and statements mean for the dialogue between Catholic social thought …

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Social Justice And The American Law School Today: Since We Are Made For Love, Michael Kaufman Oct 2017

Social Justice And The American Law School Today: Since We Are Made For Love, Michael Kaufman

Seattle University Law Review

This Article is intended to facilitate that new dialogue by finding a series of profound provocations in the Pope’s teachings. First, the Pope provokes us to consider whether our existing education and economic systems are based on an incomplete understanding of human nature.5 The first section contends that the understanding that human beings are by nature competitive and consumptive wealth maximizers is not only contrary to the Pope’s teachings but also contrary to the latest research in the fields of neuroscience, neuro-psychology, cognitive psychology, educational psychology, economics, and behavioral economics. Second, the Pope provokes us to consider whether our existing …

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The Missouri Miner, October 5, 2017 Oct 2017

The Missouri Miner, October 5, 2017

The Missouri Miner Newspaper

No abstract provided.

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Technological Variability At Sibudu Cave: The End Of Howiesons Poort And Reduced Mobility Strategies After 62,000 Years Ago, Paloma De La Peña, Lyn Wadley Oct 2017

Technological Variability At Sibudu Cave: The End Of Howiesons Poort And Reduced Mobility Strategies After 62,000 Years Ago, Paloma De La Peña, Lyn Wadley

KIP Articles

We evaluate the cultural variation between the youngest Howiesons Poort layer (GR) and the oldest post-Howiesons Poort layers (RB-YA) of Sibudu Cave (KwaZulu-Natal, South Africa). We first conducted a technological analysis, secondly we performed a cladistic study with all the technological traits and, finally, we compare the technological variability with other data from Sibudu (ochre, micromorphology, fauna and plant remains). The synapomorphies of the cladistical analysis show numerous lithic technological changes between the youngest Howiesons Poort and the oldest post-Howiesons Poort layers as previously concluded. However, some technological strategies that are present, yet uncommon, in the Howiesons Poort become abundant …

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Daily Eastern News: October 05, 2017, Eastern Illinois University Oct 2017

Daily Eastern News: October 05, 2017, Eastern Illinois University

October

No abstract provided.

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Montana Kaimin, October 5-11, 2017, Students Of The University Of Montana, Missoula Oct 2017

Montana Kaimin, October 5-11, 2017, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

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Chanticleer | October 5, 2017, Jacksonville State University Oct 2017

Chanticleer | October 5, 2017, Jacksonville State University

Chanticleer

No abstract provided.

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Investigating The Effects Of Environmental Solutes On The Reaction Environment In Ice And At Ice Surfaces, Philip Malley Oct 2017

Investigating The Effects Of Environmental Solutes On The Reaction Environment In Ice And At Ice Surfaces, Philip Malley

Dissertations - ALL

The reaction environments present in water, ice, and at ice surfaces are physically distinct from one another and studies have shown that photolytic reactions can take place at different rates in the different media. Kinetics of reactions in frozen media are measured in snow and ice prepared from deionized water. This reduces experimental artifacts, but is not relevant to snow in the environment, which contains solutes. We have monitored the effect of nonchromophoric (will not absorb sunlight) organic matter on the photolytic fate of the polycyclic aromatic hydrocarbons (PAHs) phenanthrene, pyrene, and anthracene in ice and at ice surfaces. Nonchromophoric …

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Global Leadership Development: Succession Planning For Nurses, Sharon M. Weinstein, Marianne E. Hess Oct 2017

Global Leadership Development: Succession Planning For Nurses, Sharon M. Weinstein, Marianne E. Hess

Biennial Convention (CONV)

Global nurse leaders are challenged to sustain the profession. Magnet designation, the Beacon award, and other programs promote healthy and healthful workplaces. How nurses feel, and how they perform, affects patient safety and health outcomes. The speaker addresses leadership principles aimed at sustaining nurses and nursing's future through engagement.

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Board Of Trustees Meeting Minutes October 5-6, 2017 Oct 2017

Board Of Trustees Meeting Minutes October 5-6, 2017

Board of Trustees Minutes

Minutes from the Wright State University Board of Trustees Meeting held on October 5-6, 2017.

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The Grizzly, October 5, 2017, Valerie Osborne, Courtney A. Duchene, Johnny Myers, Min Son, Madison Bradley, Emily Jolly, Kevin Leon, Sophia Dibattista, David Mendelsohn Oct 2017

The Grizzly, October 5, 2017, Valerie Osborne, Courtney A. Duchene, Johnny Myers, Min Son, Madison Bradley, Emily Jolly, Kevin Leon, Sophia Dibattista, David Mendelsohn

Ursinus College Grizzly Newspaper, 1978 to Present

The Fringe Festival Returns to Ursinus • U-Imagine Hosts Marketing Contest • UCARE Holds Voter Registration Drive and Local Election Panel • Q&A with Aneesah Smith: Ally Training Facilitator • Breaking Through the Haze • Perspective from the Past • Opinions: NFL Players Take a Knee to Stand up Against Injustice; Recent Natural Disasters Demand More Human Decency • Moving the Chains: Inside Look at the UC Chain Gang • UC Swimming Dives in for Midnight Madness

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Warming Soils, Warming Earth, Unh Communications And Public Affairs Oct 2017

Warming Soils, Warming Earth, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

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Global Leadership Development: Expanding The Voice Of Nurse Leaders And Clinical Nurses Together, Ann Marie T. Brooks Oct 2017

Global Leadership Development: Expanding The Voice Of Nurse Leaders And Clinical Nurses Together, Ann Marie T. Brooks

Biennial Convention (CONV)

Nursing is recognized as the most trusted profession in the US Gallup poll for the past 14 years. Strategies for using this important distinction for nurses to use as they advocate, influence, collaborate, translate, navigate and drive change in the US and globally will be discussed and evaluated for feasibility.

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Shadow Of The Bat[Mobile]: Character Copyright After Dc Comics V. Towle, Missy G. Brenner Oct 2017

Shadow Of The Bat[Mobile]: Character Copyright After Dc Comics V. Towle, Missy G. Brenner

Santa Clara Law Review

Shadow of the Bat[mobile]: Character Copyright After DC Comics v. Towle

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Observer, Central Washington University Oct 2017

Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for October 5-11, 2017. Vol. 108, No. 2.

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Mir-181a Increases Foxo1 Acetylation And Promotes Granulosa Cell Apoptosis Via Sirt1 Downregulation., Mei Zhang, Qun Zhang, Yali Hu, Lu Xu, Yue Jiang, Chunxue Zhang, Lijun Ding, Ruiwei Jiang, Jianxin Sun, Haixiang Sun, Guijun Yan Oct 2017

Mir-181a Increases Foxo1 Acetylation And Promotes Granulosa Cell Apoptosis Via Sirt1 Downregulation., Mei Zhang, Qun Zhang, Yali Hu, Lu Xu, Yue Jiang, Chunxue Zhang, Lijun Ding, Ruiwei Jiang, Jianxin Sun, Haixiang Sun, Guijun Yan

Center for Translational Medicine Faculty Papers

Oxidative stress impairs follicular development by inducing granulosa cell (GC) apoptosis, which involves enhancement of the transcriptional activity of the pro-apoptotic factor Forkhead box O1 (FoxO1). However, the mechanism by which oxidative stress promotes FoxO1 activity is still unclear. Here, we found that miR-181a was upregulated in hydrogen peroxide (H

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A Critique Of Pope Francis’S Laudato Si’, Nicholas Capaldi Oct 2017

A Critique Of Pope Francis’S Laudato Si’, Nicholas Capaldi

Seattle University Law Review

This is a critique of Pope Francis’s encyclical Laudato si’. The author summarizes and examines Pope Francis’s description of the problem, analysis of the roots of the problem, and proposed solution of the problem within the context of the Roman Catholic tradition. The author concludes that the encyclical abandons rigorous argument, as it lists complaints without offering substantive alternatives.

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The Cowl - V.82 - N.5 - Oct 5, 2017 Oct 2017

The Cowl - V.82 - N.5 - Oct 5, 2017

The Cowl

The Cowl - student newspaper of Providence College. Volume 82, Number 5 - October 5, 2017. 24 pages.

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Identifying Ecologically Relevant Scales Of Habitat Selection: Diel Habitat Selection In Elk, Caleb P. Roberts, James W. Cain Iii, Robert D. Cox Oct 2017

Identifying Ecologically Relevant Scales Of Habitat Selection: Diel Habitat Selection In Elk, Caleb P. Roberts, James W. Cain Iii, Robert D. Cox

Department of Agronomy and Horticulture: Faculty Publications

Although organisms make resource selection decisions at multiple spatiotemporal scales, not all scales are ecologically relevant to any given organism. Ecological patterns and rhythms such as behavioral and climatic patterns may provide a consistent method for identifying ecologically relevant scales of habitat selection. Using elk (Cervus canadensis) as an example species, we sought to test the ability of behavioral patterns to empirically partition diel scales for modeling habitat selection. We used model selection to partition diel scales by shifts in dominant behavior and then used resource selection probability functions to model elk habitat selection hierarchically at diel scales within seasons. …

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Asean And Intellectual Property: Will A Complicated History Lead To A Certain Future?, Peter N. Fowler, Teerin Charoenpot, Cheepchanok Chernkwanma Oct 2017

Asean And Intellectual Property: Will A Complicated History Lead To A Certain Future?, Peter N. Fowler, Teerin Charoenpot, Cheepchanok Chernkwanma

Loyola of Los Angeles International and Comparative Law Review

No abstract provided.

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Interleukin-17 Limits Hypoxia-Inducible Factor 1Α And Development Of Hypoxic Granulomas During Tuberculosis, Racquel Domingo-Gonzalez, Shibali Das, Kristin L. Griffiths, Mushtaq Ahmed, Monika Bambouskova, Suhas Gondi, Noor Al-Hammadi, Reid Townsend, Maxim N. Artyomov, Shabaana A. Khader, Et Al. Oct 2017

Interleukin-17 Limits Hypoxia-Inducible Factor 1Α And Development Of Hypoxic Granulomas During Tuberculosis, Racquel Domingo-Gonzalez, Shibali Das, Kristin L. Griffiths, Mushtaq Ahmed, Monika Bambouskova, Suhas Gondi, Noor Al-Hammadi, Reid Townsend, Maxim N. Artyomov, Shabaana A. Khader, Et Al.

Open Access Publications

Mycobacterium tuberculosis (Mtb) is a global health threat, compounded by the emergence of drug-resistant strains. A hallmark of pulmonary tuberculosis (TB) is the formation of hypoxic necrotic granulomas, which upon disintegration, release infectious Mtb. Furthermore, hypoxic necrotic granulomas are associated with increased disease severity and provide a niche for drug-resistant Mtb. However, the host immune responses that promote the development of hypoxic TB granulomas are not well described. Using a necrotic Mtb mouse model, we show that loss of Mtb virulence factors, such as phenolic glycolipids, decreases the production of the proinflammatory cytokine IL-17 (also referred to as IL-17A). IL-17 …

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