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2017

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2017-October-20-'Fl3tch3r' Juror Talk, University Marketing And Communications, East Tennessee State University Oct 2017

2017-October-20-'Fl3tch3r' Juror Talk, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

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The Echo: October 20, 2017, Taylor University Oct 2017

The Echo: October 20, 2017, Taylor University

2017-2018 (Volume 105)

Welcome, Mr. President – Pass go – No game today – After school art program kicks off – Taking a knee – Taylor alumnus crowned Indiana’s top teacher – Uncovering Taylor’s own Indiana Jones – Custom costumes without the cost – Geocaching Definitions – Geocache me outside – The Bi-weekly Bachelor and Bachelorette – Brecken’s Breakdown – Echograms #TaylorU -- #TaylorU’s Tweets – Heartland is for film lovers – We are women – Welcome back, Marion Philharmonic! – Muslim students on our doorstep – Pollard sets record in Trojans loss – Weekly Preview – Men’s soccer gives their seniors a …

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Tnf-Α Promotes Nuclear Enrichment Of The Transcription Factor Tonebp/Nfat5 To Selectively Control Inflammatory But Not Osmoregulatory Responses In Nucleus Pulposus Cells., Zariel I. Johnson, Alexandra C. Doolittle, Joseph W. Snuggs, Irving M. Shapiro, Christine L. Le Maitre, Makarand V. Risbud Oct 2017

Tnf-Α Promotes Nuclear Enrichment Of The Transcription Factor Tonebp/Nfat5 To Selectively Control Inflammatory But Not Osmoregulatory Responses In Nucleus Pulposus Cells., Zariel I. Johnson, Alexandra C. Doolittle, Joseph W. Snuggs, Irving M. Shapiro, Christine L. Le Maitre, Makarand V. Risbud

Department of Orthopaedic Surgery Faculty Papers

Intervertebral disc degeneration (IDD) causes chronic back pain and is linked to production of proinflammatory molecules by nucleus pulposus (NP) and other disc cells. Activation of tonicity-responsive enhancer-binding protein (TonEBP)/NFAT5 by non-osmotic stimuli, including proinflammatory molecules, occurs in cells involved in immune response. However, whether inflammatory stimuli activate TonEBP in NP cells and whether TonEBP controls inflammation during IDD is unknown. We show that TNF-α, but not IL-1β or LPS, promoted nuclear enrichment of TonEBP protein. However, TNF-α-mediated activation of TonEBP did not cause induction of osmoregulatory genes. RNA sequencing showed that 8.5% of TNF-α transcriptional responses were TonEBP-dependent and …

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Searching Infinity For Authentic Form: The Problem Of Memoir, Annmarie Lynn Dill Oct 2017

Searching Infinity For Authentic Form: The Problem Of Memoir, Annmarie Lynn Dill

Theses and Dissertations

This thesis is a rhetorical analysis of the genre of memoir specifically examining the language used to define, describe, and critique the genre, focusing on the ways the language undermines memoir’s generic value. Since the 1990’s memoir has become increasingly popular, but lacks much academic investigation or critique into the conventions of the genre, though it has amassed much criticism. The genre’s rhetorical situation is at odds with general academic standards because inquiry must come before conclusive evaluations. To bridge this gap in scholarship, I have used methods of rhetorical criticism to analyze the definitions of memoir produced by five …

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“I Feel Like I’M Drawing Strength From It”: Lived Experiences Of Filipino Elderly Participating In Craft-Making, Sharon B. Cajayon, Romeo Luis A. Macabasag, Norilyn Limchanco, Vanessa O. Umali, Ellayza N. Blas, Michelle S. Angulo, Cristine Joy A. Breguera, Nikka Angela A. De Guzman, Sheila N. Malapi, Emmalyn E. Quibote Oct 2017

“I Feel Like I’M Drawing Strength From It”: Lived Experiences Of Filipino Elderly Participating In Craft-Making, Sharon B. Cajayon, Romeo Luis A. Macabasag, Norilyn Limchanco, Vanessa O. Umali, Ellayza N. Blas, Michelle S. Angulo, Cristine Joy A. Breguera, Nikka Angela A. De Guzman, Sheila N. Malapi, Emmalyn E. Quibote

The Qualitative Report

In this phenomenological study, we offer an insightful understanding of the lived experiences of seven (7) Filipino elderly participating in craft-making. We purposively selected the key informants from a municipality in the province of Bulacan, Philippines. The transcribed data gathered through a semi-structured in-depth interview was analyzed using Colaizzi’s approach. Six themes describing the lived experiences emerged: “Fostering friendship,” “Flourishing health,” “Furthering service,” “Facing aging with acceptance,” “Finding felicity and self-fulfillment,” “Feelings of belongingness and security.” Just like the sun, the elderly’s participation in craft-making serves as a nourishment for them. This exploration speaks to understanding the potential of craft-making …

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Learning A Language: The Gateway To Cosmopolitanism, Caleb Griffin Oct 2017

Learning A Language: The Gateway To Cosmopolitanism, Caleb Griffin

Theses and Dissertations

This thesis explores the relationship between language acquisition and ethnocentrism. Specifically, does learning additional languages reduce ethnocentrism in an individual? After reviewing the literature on social groups, ethnocentrism, and language acquisition, a quantitative test was carried out. This consisted of a survey design implemented in Morocco using Moroccan subjects. Although learning additional languages was correlated with less ethnocentrism, the results did not meet the threshold for statistical significance. The variables that did have a statistically significant impact on ethnocentrism and prejudice were contact and age.

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Introduction To The Finite-Difference Time-Domain (Fdtd) Technique, Bruce Archambeault Oct 2017

Introduction To The Finite-Difference Time-Domain (Fdtd) Technique, Bruce Archambeault

Electrical and Computer Engineering Faculty Research & Creative Works

No abstract provided.

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Intravesical Rad-Ifnα/Syn3 For Patients With High-Grade, Bacillus Calmette-Guerin-Refractory Or Relapsed Non-Muscle-Invasive Bladder Cancer: A Phase Ii Randomized Study., Neal D Shore, Stephen A Boorjian, Daniel J Canter, Kenneth Ogan, Lawrence I Karsh, Tracy M Downs, Leonard G Gomella, Ashish M Kamat, Yair Lotan, Robert S Svatek, Trinity J Bivalacqua, Robert L Grubb, Tracey L Krupski, Seth P Lerner, Michael E Woods, Brant A Inman, Matthew I Milowsky, Alan Boyd, F Peter Treasure, Gillian Gregory, David G Sawutz, Seppo Yla-Herttuala, Nigel R Parker, Colin P N Dinney Oct 2017

Intravesical Rad-Ifnα/Syn3 For Patients With High-Grade, Bacillus Calmette-Guerin-Refractory Or Relapsed Non-Muscle-Invasive Bladder Cancer: A Phase Ii Randomized Study., Neal D Shore, Stephen A Boorjian, Daniel J Canter, Kenneth Ogan, Lawrence I Karsh, Tracy M Downs, Leonard G Gomella, Ashish M Kamat, Yair Lotan, Robert S Svatek, Trinity J Bivalacqua, Robert L Grubb, Tracey L Krupski, Seth P Lerner, Michael E Woods, Brant A Inman, Matthew I Milowsky, Alan Boyd, F Peter Treasure, Gillian Gregory, David G Sawutz, Seppo Yla-Herttuala, Nigel R Parker, Colin P N Dinney

Department of Medicine Faculty Papers

Purpose Many patients with high-risk non-muscle-invasive bladder cancer (NMIBC) are either refractory to bacillus Calmette-Guerin (BCG) treatment or may experience disease relapse. We assessed the efficacy and safety of recombinant adenovirus interferon alfa with Syn3 (rAd-IFNα/Syn3), a replication-deficient recombinant adenovirus gene transfer vector, for patients with high-grade (HG) BCG-refractory or relapsed NMIBC. Methods In this open-label, multicenter (n = 13), parallel-arm, phase II study ( ClinicalTrials.gov identifier: NCT01687244), 43 patients with HG BCG-refractory or relapsed NMIBC received intravesical rAd-IFNα/Syn3 (randomly assigned 1:1 to 1 × 10(11) viral particles (vp)/mL or 3 × 10(11) vp/mL). Patients who responded at months 3, …

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American Trade News Highlights For Fall 2013: The Chilling Effect Of Cool On The Livestock Trade Of Mexico, Canada, And The United States, Vanessa Humm Oct 2017

American Trade News Highlights For Fall 2013: The Chilling Effect Of Cool On The Livestock Trade Of Mexico, Canada, And The United States, Vanessa Humm

Law and Business Review of the Americas

No abstract provided.

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Child Labor In Latin America, Soo Nam Oct 2017

Child Labor In Latin America, Soo Nam

Law and Business Review of the Americas

No abstract provided.

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Remarks By United States Trade Representative Michael Froman At The Transatlantic Trade And Investment Partnership First Round Opening Plenary Oct 2017

Remarks By United States Trade Representative Michael Froman At The Transatlantic Trade And Investment Partnership First Round Opening Plenary

Law and Business Review of the Americas

No abstract provided.

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Nafta Updates And American Trade News Highlights For Fall 2012, Sarah Bridges Oct 2017

Nafta Updates And American Trade News Highlights For Fall 2012, Sarah Bridges

Law and Business Review of the Americas

No abstract provided.

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Haitian Sun And Peruvian Ruins: Service-Learning In International Development, Paige Rudin Oct 2017

Haitian Sun And Peruvian Ruins: Service-Learning In International Development, Paige Rudin

Purdue Journal of Service-Learning and International Engagement

Development issues in growing nations can be seen and discussed in service-learning programs on Purdue’s campus. Two international experiences in Haiti and Peru reveal a need for development strategies that can be universally applied in service-learning settings. Traveling with graduate students from Lima, Peru, to study animal connection in Peruvian society and teaching Haitian university students the basics of water quality and testing allow the exchange of ideas between cultures and profound learning for both parties. Connections like these change mindsets and inspire curiosity, thus strengthening human capacity. Challenges and barriers like integrating quantitative and qualitative data from community partners …

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The Role Of Public Interest Groups In Nation-Building: A Maine Lawyer's Experience In Mongolia, Richard A. Spencer Oct 2017

The Role Of Public Interest Groups In Nation-Building: A Maine Lawyer's Experience In Mongolia, Richard A. Spencer

Maine Law Review

In 2006, I spent three months in Ulaanbaatar, Mongolia working as an environmental lawyer with a small Mongolian human rights group called the Center for Human Rights and Development (CHRD). CHRD was working to stop human trafficking, promote human rights, and protect the environment in the face of extreme poverty, government secrecy, corruption, and a post-Soviet government dominated by former members of the Communist party. During my time assisting the staff at CHRD, I felt I could hear the voice of James Madison echoing through the centuries and across the globe. In The Federalist No. 10, Madison suggested that the …

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Measuring The Rule Of Law In India: A Volunteer Lawyer's Experience, Linda D. Mcgill Oct 2017

Measuring The Rule Of Law In India: A Volunteer Lawyer's Experience, Linda D. Mcgill

Maine Law Review

When I set off for New Delhi, India in January 2003 to serve as a volunteer with the International Senior Lawyers Project (ISLP), nation-building was not in my mission statement. After all, India is the world’s largest democratic country, sustaining that status for sixty years from its violent birth by partition through the curtailment of individual freedoms in the 1975 “emergency” to its recent emergence as a “giant” of economic development and intellectual capital. India’s hold on democracy is all the more impressive given the religious and cultural differences among its vast population and the legacy of still-simmering resentments from …

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Looking Backward To Address The Future? Transitional Justice, Rising Crime And Nation Building, James L. Cavallaro Oct 2017

Looking Backward To Address The Future? Transitional Justice, Rising Crime And Nation Building, James L. Cavallaro

Maine Law Review

This is not an Article about the Nazi regime’s war on crime, nor does it analyze the possible lawlessness of the Weimar Republic. It does, however, consider the role of crime in transitional states. As such, the observation above is relevant to the issues examined in the pages that follow. Crime and the manipulation of the fear it promotes were essential to the rise of Nazism, the fall of the Weimar Republic, and the historical record of both regimes. I contend that we must recognize the vital role of street crime in the stability and instability of newly democratic and …

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Culture And Custom In Nation-Building: Law In Afghanistan, Thomas Barfield Oct 2017

Culture And Custom In Nation-Building: Law In Afghanistan, Thomas Barfield

Maine Law Review

Afghanistan’s restoration of the rule of law has set in motion a renewed debate about fundamental legal principles that has not been seen in the West since the time of the Enlightenment: Who is justice for? Who has the right to seek compensation or justice? Does the state or the individual have priority in seeking justice and delivering punishment? Is law a human creation or is it rooted in divine authority? But it is a debate without an audience in the international community that is assisting the Afghan government in restoring its judicial system because the answer appears so self-evident. …

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Human Rights And Nation-Building In Cross-Cultural Settings, Burns H. Weston Oct 2017

Human Rights And Nation-Building In Cross-Cultural Settings, Burns H. Weston

Maine Law Review

Values are preferred events, “goods” we cherish; and the value of respect, “conceived as the reciprocal honoring of freedom of choice about participation in value processes,” is “the core value of human rights.” In a world of diverse cultural traditions that is simultaneously distinguished by the widespread universalist claim that “human rights extend in theory to every person on earth without discriminations irrelevant to merit,” the question thus unavoidably arises: when, in human rights decision-making, are cultural differences to be respected and when are they not? The question arises early in the nation-building enterprise where demands to preserve cultural traditions …

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The Legal Architecture Of Nation-Building: An Introduction, Charles H. Norchi Oct 2017

The Legal Architecture Of Nation-Building: An Introduction, Charles H. Norchi

Maine Law Review

In the future, a historian studying the early twenty-first century will observe a trend: numerous lawyers applying their skill sets to the problems of pathological states. Our future historian will note that the topography of the post-Cold War international system was marked by weakly-governed states failing. Fragile states eroded, frayed, and disintegrated under stress, and their internal social processes became highly susceptible to external forces. Powerful non-state actors, including private armies, operated within the porous boundaries of entities that were once functioning polities. Legal authority became divorced from political control as non-state actors wielded naked power, challenging formal state structures …

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Observer, Central Washington University Oct 2017

Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for October 19-25, 2017. Vol. 108, No. 4.

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Structural Optimization And Behavioral Analysis Of Antagonists Of The Insect Odorant Receptor Co-Receptor Subunit, Devin Kepchia Oct 2017

Structural Optimization And Behavioral Analysis Of Antagonists Of The Insect Odorant Receptor Co-Receptor Subunit, Devin Kepchia

Open Access Dissertations

Response to volatile environmental chemosensory cues is essential for insect survival. The odorant receptor (OR) family is an important class of receptors that detects volatile molecules. Importantly, olfaction is a key component of the multimodal approach used by mosquitoes to target and feed on humans. Current repellents have drawbacks, necessitating development of more effective agents. Insect ORs are odorant-gated ion channels, consisting of a variable odorant specificity subunit and a conserved odorant receptor co-receptor (Orco) subunit. The Orco subunit possesses an allosteric site to which modulators can bind and inhibit odorant activation of ORs. All insect ORs contain Orco, and …

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Kinome And Transcriptome Profiling Reveal Broad And Distinct Activities Of Erlotinib, Sunitinib, And Sorafenib In The Mouse Heart And Suggest Cardiotoxicity From Combined Signal Transducer And Activator Of Transcription And Epidermal Growth Factor Receptor Inhibition, T. J. Stuhlmiller, J. S. Zawistowski, X. Chen, N. Sciaky, S. P. Angus, S. T. Hicks, T. L. Parry, W. Huang, J. Y. Beak, M. S. Willis, G. L. Johnson, B. C. Jensen Oct 2017

Kinome And Transcriptome Profiling Reveal Broad And Distinct Activities Of Erlotinib, Sunitinib, And Sorafenib In The Mouse Heart And Suggest Cardiotoxicity From Combined Signal Transducer And Activator Of Transcription And Epidermal Growth Factor Receptor Inhibition, T. J. Stuhlmiller, J. S. Zawistowski, X. Chen, N. Sciaky, S. P. Angus, S. T. Hicks, T. L. Parry, W. Huang, J. Y. Beak, M. S. Willis, G. L. Johnson, B. C. Jensen

Pharmaceutical Sciences

No abstract provided.

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The Moral Dimensions Of The Research Reproducibility Crisis, Rachel Robinson-Greene Oct 2017

The Moral Dimensions Of The Research Reproducibility Crisis, Rachel Robinson-Greene

Languages, Philosophy, and Communication Studies Faculty Publications

The labor of scientists has benefited society tremendously. Advancements in medicine and technology have improved both the length and the quality of human lives. Scientific studies have been and continue to be a crucial part of that process. Science, when done well, is indispensable to a healthy, happy, curious human race. Unfortunately, science isn’t always done well. When done poorly, studies can have disastrous effects. People tend to trust claims made by scientists, and that trust turns out to be unwarranted if something has gone wrong with the research.

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The Setonian, October 19, 2017, Seton Hall University Oct 2017

The Setonian, October 19, 2017, Seton Hall University

2017

No abstract provided.

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3d Bioprinting Patentable Subject Matter Boundaries, Tabrez Y. Ebrahim Oct 2017

3d Bioprinting Patentable Subject Matter Boundaries, Tabrez Y. Ebrahim

Seattle University Law Review

3D bioprinting combines emerging 3D printing technologies with synthetic biology. The promise of 3D bioprinting technology is to fabricate organs for transplantation, treat burn victims with in vivo skin repair, and create wearable microbiomes. 3D bioprinting can successively build, repair, or reproduce living human cells. This capability challenges eligible subject matter doctrine in U.S. patent law because the law has no brightline standard for patent eligibility for nature-based products. As 3D bioprinting technologies mature, U.S. patent law will need to respond to situations where living and nonliving worlds merge. This Article proposes a “Mixed-Scanned-Transformed” standard to supplement U.S. patent law’s …

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Gardner-Webb Graduate Takes Research Interests To Exciting Places, Office Of University Communications, Mallory Moore Oct 2017

Gardner-Webb Graduate Takes Research Interests To Exciting Places, Office Of University Communications, Mallory Moore

Gardner-Webb NewsCenter Archive

Christopher Lile, who graduated in 2017 with a biology degree, is taking the research skills he developed at Gardner-Webb University to new and exciting places. Since leaving Gardner-Webb, Lile completed an internship at Wolf Park in Battle Ground, Ind., where he trained grey wolves and worked in husbandry and public education. His love for animals, research, and conservation have now led him to the island of Madagascar, where he is spending three months studying lemurs as a volunteer for the Omaha Zoo’s Department of Conservation Genetics.

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The Excited Utterance Paradox, Steven Baicker-Mckee Oct 2017

The Excited Utterance Paradox, Steven Baicker-Mckee

Seattle University Law Review

Based on nothing more than John Henry Wigmore’s personal belief that a witness under the throes of excitement is unable to fabricate an untruthful statement, the excited utterance exception allows parties to present out-of-court statements to the jury or judge without any of the safeguards the judicial system uses to promote honest and accurate testimony. This Article collects and examines much of the scientific evidence bearing on Wigmore’s premise and identifies two paradoxical conclusions that undermine the exception. First, the premise itself is unfounded; science absolutely does not support the notion that a witness is incapable of lying while emotionally …

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Salmon With A Side Of Genetic Modification: The Fda’S Approval Of Aquadvantage Salmon And Why The Precautionary Principle Is Essential For Biotechnology Regulation, Kara M. Van Slyck Oct 2017

Salmon With A Side Of Genetic Modification: The Fda’S Approval Of Aquadvantage Salmon And Why The Precautionary Principle Is Essential For Biotechnology Regulation, Kara M. Van Slyck

Seattle University Law Review

This Note seeks to address the issues concerning the FDA’s approval of genetically modified salmon for consumption, arguing that the FDA did not properly vet AquAdvantage salmon, as well as relied on inappropriate criteria in their approval of its market use. Part I provides a brief history of AquAdvantage salmon’s introduction to U.S. markets and the legal actions taken in response to the FDA ruling. Part II discusses the statutes and regulations fundamentally relevant to GE products, as well as a critique of the way each regulation was used to approve AquAdvantage. Part III offers a comparison to the European …

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The Missouri Miner, October 19, 2017 Oct 2017

The Missouri Miner, October 19, 2017

The Missouri Miner Newspaper

No abstract provided.

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Last Words Of Torrey Mcnabb, Torrey Mcnabb, Esther Brown Oct 2017

Last Words Of Torrey Mcnabb, Torrey Mcnabb, Esther Brown

Execution Artifacts and Eyewitness Accounts

The last words of Torrey McNabb before his execution by lethal injection on October 19th, 2017. Donated to the archive by Esther Brown.

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