Digital Commons Network^™

Variations In Video Game Play Habits And Beliefs Over Time, John Adam Campbell

Theses and Dissertations

Psychological research about the consequences of playing video games has grown exponentially, correlating to the exponential growth of the video game industry. In the past decade, a major impetus has related to the concept of video game addiction, pathological gaming, or Internet Gaming Disorder. While the presence of this problem is widely accepted and there is growing knowledge about the factors contributing to its development and perpetuation, there is minimal research speaking to intervention. The primary purpose of the present study was to identify a potential pathway to educate members of the gaming community about pathological gaming, with the hope …

Regulating Cumulative Risk, Sanne H. Knudsen

Articles

This Article proceeds in four parts. Part I describes how cumulative risk assessments tackle the real-world exposure problems that lie at the heart of public health. It shows how risk science has evolved and why policy, not science, lags behind. Part II then examines why key public health concerns cannot be answered through information disclosure or consumer choice models alone.

Having established that regulatory drivers are needed, Part III begins to examine how to move forward. It does so by looking backward and examining how TSCA and FIFRA have failed historically to provide this critical public health focus despite room …

Give It To Me, I'M Worth It: The Need To Amend Georgia's Record Restriction Statute To Provide Ex-Offenders With A Second Chance In The Employment Sector, Bonita A. Huggins

Georgia Law Review

In the era of mass criminalization, where over 70
million Americans and almost four million Georgians
have a criminal record, the collateral consequences that
accompany criminal records have become barriers to
employment for many ex-offenders trying to reenter the
workforce. Blanket exclusionary hiring policies that
apply to all individuals with a record regardless of the
nature of the offense or time since its commission have
left a portion of the population with little to no
opportunity to act as productive, contributing members
of society.
Georgia's current statutory scheme built to alleviate
the effects of the collateral consequences of a criminal …

Amphetamine Exposure During Embryogenesis Leads To Long-Term And Transgenerational Increase In Behavioral Response And Decrease In Dopamine Uptake, Talus J. Mccowan

Theses and Dissertations

Amphetamine (AMPH) is widely prescribed for the treatment of ADHD and a highly abused substance in society, yet little is known about the long-term effects of the drug. Here, we used Caenorhabditis elegans (C. elegans) to establish a model for the long-term and transgenerational effects of AMPH exposure on behavior. Furthermore, experiments were conducted to explore the molecular mechanisms of AMPH that were altered by embryonic AMPH exposure.

C. elegans have a well characterized behavioral response to AMPH known as Swimming Induced Paralysis (SWIP). For the SWIP test, animals are placed in fluid, which normally induces a thrashing behavior. However, …

Intergenerational Effects Of Embryonic Cocaine Exposure In Zebrafish, Cody Adam Boyle

Theses and Dissertations

Cocaine addiction has both genetic and environmentally driven components. Relatively recently several groups have suggested that epigenetic regulation of gene expression might be the mechanism linking environmental influence and inheritance in drug addiction. We have shown previously that embryonic cocaine exposure increases physiological and behavioral sensitivity to the drug in longitudinal adults. In this study, we provide evidence that the effects of embryonic pre-exposure to cocaine are intergenerational in zebrafish. In addition, we show how gene expression in the zebrafish telencephalon, which includes the teleost equivalent of the nucleus accumbens, changes during acute cocaine treatment during behavioral testing. These experiments …

Mechanistic Insights Into Neutrophil Turnover During Gram-Negative Pneumonic Sepsis, Christopher Jondle

Theses and Dissertations

Sepsis is one of the oldest and most elusive syndromes in medicine. It is characterized by a systemic inflammatory response leading to acute organ dysfunction. In the United States alone there are over 750,000 cases of sepsis each year, with a mortality rate between 20-50%. Sepsis is the second leading cause of death in the ICU and the tenth leading cause of death overall in the United States. Over half of all ICU resources are consumed in the treatment of sepsis. There are currently no effective therapies available against sepsis, all attempts to develop an effective therapy have failed. Respiratory …

Young Children's Articulations Of Their Metacognitive Processing During Play, Dawnita S. Nilles

Theses and Dissertations

The purpose of this phenomenological qualitative research study was to hear young children’s descriptions of their metacognitive processes. Research has shown that play is the foundation of a child’s learning and numerous studies show that play affects all areas of a child’s development. Despite this, at the time of this study, there appeared to be a scarcity of published literature in which young children were interviewed about the metacognitive processes they use while playing. Children have been found to describe their thinking through non-verbal cues. They also have been able to articulate their knowledge and understanding, analyze, and evaluate the …

Optimal Control Of Induction Machines To Minimize Transient Energy Losses, Siby Jose Plathottam

Theses and Dissertations

Induction machines are electromechanical energy conversion devices comprised of a stator and a rotor. Torque is generated due to the interaction between the rotating magnetic field from the stator, and the current induced in the rotor conductors. Their speed and torque output can be precisely controlled by manipulating the magnitude, frequency, and phase of the three input sinusoidal voltage waveforms. Their ruggedness, low cost, and high efficiency have made them ubiquitous component of nearly every industrial application. Thus, even a small improvement in their energy efficient tend to give a large amount of electrical energy savings over the lifetime of …

The Role Of Α-Synuclein In Brain Lipid Metabolism And Inflammation, Drew R. Seeger

Theses and Dissertations

Alpha-synuclein (Snca) is a small cytosolic protein that is ubiquitously expressed in the nervous system and comprises 0.5-1% of all cytosolic protein, but its biological function is poorly understood. Although Snca function has been studied in lipid metabolism, the function of Snca in brain lipid metabolism under inflammatory conditions is yet to be elucidated. We utilized several model systems including primary cultured astrocytes and microglia, Snca deficient and mutant knock-in mice, and a radiolabeled free fatty acid steady state-kinetic mouse model to determine Snca role in neuroinflammation. Herein, we have determined several major roles of Snca during inflammation: (i) dBcAMP …

Modification Methods For Soil And Water Assessment Tool (Swat) Performance In Simulating Runoff And Sediment Of Watersheds In Cold Regions, Bahareh Shoghli

Theses and Dissertations

Streamflow predication is an important task in water management studies. It is needed in the operation and optimization of water resources and flood control projects. The accuracy of these predictions has a great influence on the water resources management and decision making processes. Various models and tool packages have been developed for simulation and prediction of streamflow. Among them, the Soil and Water Assessment Tool (SWAT) is one of the most widely used models, which was originally developed to predict the impacts of land management on water, sediment and agricultural chemical yield in large watershed simulations. Results of the SWAT …

Quantification Of Lignin Hydroxyl Containing Functional Groups Via 31p{1h} Nmr Spectroscopy And Synthesis Of Lignin Degradation Standards, Joshua E. Schumaker

Theses and Dissertations

The focus of this thesis is on the structural characterization of lignin, a complex phenol-based heteropolymer. In the first part of the study, functionalization of lignin and its known degradation products by 2-chloro-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane (TMDP) and analysis by 31P NMR spectroscopy was investigated. Chemical shifts of derivatized alcohols, phenols, and carboxylic acids were determined that allowed for qualitative characterization of lignin. This approach was further applied for the quantitative analysis of OH-containing groups present in lignin employing the internal standard. Lignin samples, fractionated by gel permeation chromatography (GPC) based on molecular weights, were derivatized by TMDP and characterized by 31P NMR …

Epigenetic Remodeling As A Mediator Of Environmental Toxicant Exposure In The Brain, Christopher David Walden

Theses and Dissertations

Natural toxins and artificial toxicants are abundant throughout our environment and may play an integral role in remodeling our epigenome and in the development of neural diseases. Exposure to heavy metals and organic pollutants, such as DDT and its derivatives, have been linked to neural disease. Additionally, there are links between direct exposure, in both adults and children, to short-lived pesticides and neural diseases. While the link has been established, understanding the root cause has yet to be elucidated. One increasingly relevant field offering promise in achieving this goal is epigenetics. Epigenetic remodeling is one potential mechanism by which environmental …

Towards Improving East Coast Fever (Ecf) Diagnosis: Validation Of Loop-Mediated Isothermal Amplification (Lamp) Assays For Rapid Detection Of Theileria Parva, The Causative Agent Of Ecf In Cattle, Moses Njahira Ndotono

All Master’s Theses

East Coast fever (ECF) is a serious tick-borne parasitic disease of cattle and is a major constraint to the livestock sector in east, central and southern Africa. ECF is caused by a protozoan parasite, Theileria parva, transmitted by the tick, Rhipicephalus appendiculatus. Several serological and molecular assays have been developed, for use in epidemiological studies, monitoring control programmes, and for research. Amongst the plethora of molecular assays for T. parva is a p104 gene nested-PCR (p104-nPCR) assay, a validated ‘gold-standard' PCR assay. However, p104-nPCR requires sophisticated equipment and 1-2 days to perform. Two simple, rapid molecular assays for T. parva, …

Situating The Corporation Within The Vulnerability Paradigm: What Impact Does Corporate Personhood Have On Vulnerability, Dependency, And Resilience, Heather Kolinsky

American University Journal of Gender, Social Policy & the Law

No abstract provided.

"Lifting As We Climb": The American Council On Human Rights And The Quest For Civil Rights, Gregory S. Parks

American University Journal of Gender, Social Policy & the Law

The narrative of African Americans’ quest for racial equality and social justice in the Twentieth Century is typically construed in the context of main-line civil rights organizations—e.g., NAACP, SCLC, SNCC, and the like. However, for decades, black fraternal networks had been helping to lay the groundwork for the major civil rights campaigns that culminated in the Civil Rights Act of 1964. In 1938 Alpha Kappa Alpha Sorority, Incorporated created the National Non-Partisan Lobby on Civil and Democratic Rights (“NPC”), later renamed the National Non-Partisan Council on Public Affairs. It was the first full-time congressional lobby for minority group civil rights. …

Slc11a1 Polymorphisms And Host Susceptibility To Cutaneous Leishmaniasis In Pakistan., Mariam Sophie,, Abdul L Hameed Institute Of Biomedical And Genetic Engineering (Ibge), 24-Mauve Area, G- 9/1, Islamabad, Pakistan., Akhtar Muneer, Azam J. Samdani, Saima Saleem, Abid Azhar

Department of Medicine

Background:The vector-borne cutaneous leishmaniasis (CL) is endemic in several regions of Pakistan mainly affecting poor populations. Host genetic factors, particularly SLC11A1 (solute carrier transmembrane protein) within macrophages, play a crucial role in disease pathology and susceptibility. Association of SLC11A1 with cutaneous leishmaniasis, a neglected tropical disease, is not well established. Inconsistencies have been observed within different populations worldwide with respect to genetic susceptibility. This study was designed to investigate genetic variation(s) in SLC11A1 and to assess possible association with cutaneous leishmaniasis in Pakistan.

Results: Eight polymorphisms (rs2276631, rs3731864, rs2290708, rs2695342, rs201565523, rs17215556, rs17235409, rs17235416) were genotyped across SLC11A1 in …

Testing The Stellar Rotation Vs. Age Paradigm Using Wide Binaries In The Kepler & K2 Fields, T. D. Oswalt, T. Otani, A. Stone-Martinez, P. Majewski, D. Buzasi

Publications

Essential to understanding the history of the Galaxy’s stellar populations, ages are among the most difficult to measure properties of stars. Accurate stellar ages would provide key leverage on problems ranging from the habitability of exoplanets to the Galaxy’s chemical evolution and age. Gyrochronology, the empirical relation between rotation and age, is believed to be among the best current methods of stellar age determination. Using several hundred wide non-interacting binaries identified in the Kepler mission “K2” extended mission fields we are testing this paradigm. Such wide pairs afford a unique opportunity to unravel and calibrate the effects of mass, rotation, …

The Ability Of The Brain To Adapt To Temporal Lobe Epilepsy In The Context Of Hemispheric Dominance For Language, Kathleen A. Breslin

PCOM Psychology Dissertations

The potential for the brain to adapt to insult or injury is demonstrated in the preservation of language functions when there is damage to the language areas (Lidzba, Staudt, Wilke, Grodd, & Krageloh-Mann, 2006). Although atypical hemispheric dominance for language is rare in the general population, rates are higher in epilepsy patients (Araujo, Schwarze, & White, 2009; Drane et al., 2012; Lidzba, Staudt, Wilke, Grodd, et al., 2006; Powell, Kemp, & Garcia-Finana, 2012; Spreer et al., 2001). Understanding this relationship and factors affecting atypicality is important for neuropsychologists in making treatment recommendations and for pre-operative planning. This study sought to …

Measuring Aggressive Behavior Perceptions, Tammarra Jones

PCOM Psychology Dissertations

No abstract provided.

Factors Influencing Illinois Soybean Yield Increase, Sydney Bollinger

Research Papers

Soybean productivity is among many important topics currently in Illinois agriculture. With corn prices being so low the last few years, many people are relying on their soybean crop to produce very well. Also, with the increasing disapproval of genetically modified crops, it is important to recognize if these crops making a difference in production. It is obvious that weather plays a huge role in crop productivity. This research is intended to identify other specific variables that influence soybean yield in a given year. Much research has been done in the past identifying the weather variables that are most important …

Hemodynamic Regulation Of Cardiac Valve Development, Vinal Menon

Theses and Dissertations

It is well established that valvulogenesis is a result of a complex interplay between genetic and environmental factors. Hemodynamics is one such environmental stimulus that is well documented to influence the development of heart valves. Using advanced imaging modalities, such as optical coherence tomography, investigators have better understood the effects of altering hemodynamic loads in the embryonic (avian) heart. However, the field of valvulogenesis is currently stagnant with a paucity of studies aiming to understand the molecular mechanisms influenced/affected by hemodynamic stimuli. Deciphering these pathways is critical from a valve development perspective, but also becomes vital as potential therapeutic targets, …

Students Diagnosed With Attention Deficit Hyperactivity Disorder: A Study Of On-Task And Off-Task Behaviors In Traditional Versus Montessori Classrooms, Sara-Frances Crow Lail

Theses and Dissertations

Attention Deficit Hyperactivity Disorder (ADHD), a common neurobehavioral disorder in childhood, negatively impacts academic and social functioning, both of which later influence adulthood (Bose, 2013). This action research study focuses on comparing the prevalence of on-task and off-task behaviors exhibited by elementary age students diagnosed with ADHD in a traditional classroom structure versus a Montessori classroom structure. While much time and research has been conducted to assist educators in meeting the needs of students with learning disabilities through interventions, less research has focused on non-conventional educational environments as an alternative for children with ADHD. In this study, on-task and off-task …

Population Dynamics Of A Recently Described And Rare Plant Species: Stachys Caroliniana (Lamiaceae), Shelby Moody

Theses and Dissertations

Stachys caroliniana J.B. Nelson & D.A. Rayner, a newly described ‘hedge-nettle’ is found in two locations in South Carolina. The first known collection of this species is from the Santee Coastal Reserve in Charleston County. The second location (the type locality) is from the Tom Yawkey Wildlife Center in Georgetown County, approximately 8 air miles northeast of the first location. This study focused on the population in Georgetown County. Population dynamics of Stachys caroliniana were studied in order to provide management guidelines to South Carolina Department of Natural Resources for this species. This was achieved by assessing suitable habitat conditions, …

We Still Need A Theory, Paula Droege

Animal Sentience

Woodruff (2017) has compiled a convincing array of data to support his contention that teleost fish feel pain. However, in the absence of an explanatory theory about the nature and function of consciousness, a checklist of criteria is insufficient to allay skeptical concerns. I offer a theory that can explain why features like selective attention and behavioral flexibility indicate consciousness. Consciousness represents the present moment in order to allow dynamic changes in actions or goals in response to situational demands.

Valproic Acid: A Neural Outgrowth Model For The Autism Spectrum Disorder, Hannah M. Bergan

Dissertations and Theses @ UNI

Autism spectrum disorder has been dramatically on the rise since the early 1990s, with one in forty-five children being diagnosed in 2014. It is known that contributing factors to autism spectrum disorder may have genetic and epigenetic origins, as well as environmental triggers. What is still unclear, however, is the impact of teratogenic drugs, consumed by the mother, have on a developing fetus in utero. How can they lead to the child developing autistic-like behaviors? The current study documents the effects of one teratogenic drug Valproic acid, a known histone deacetylase inhibitor. It establishes the role it plays on developing …

Factors Influencing Wood Turtle (Glyptemys Insculpta) Home Range Size In Iowa: A Comparison Between Suburban And Rural Populations, Joshua Gregory Otten

Dissertations and Theses @ UNI

Home range size, movement patterns, and site fidelity of wood turtles (Glyptemys insculpta) were compared between a suburban population in Black Hawk County (BH) and a rural population in Butler County (BC), Iowa. Approximately 89% of individuals captured for studies conducted in Iowa during 2014 and 2015 were >14 years old. 45 individuals (22 females, 18 males, and 5 juveniles) were used for radio telemetry surveys in 2014–2015, 24 of which were located in BC, and 21 at BH.

Home range size of male and female wood turtles was significantly different at the 100% Minimum Convex Polygon (MCP), …

Association Of Various Concentrations Of Cat's Claw Herb (Uncaria Tomentosa) On Lymphocyte Proliferation And Nitric Oxide Expression: An In-Vitro Study Of Osteoarthritis, Noha Fadlalddin

Dissertations and Theses @ UNI

Uncaria tomentosa, also known as cat’s claw, is an indigenous herb which originates from the Amazon River basin and has proven to be highly effective via case report and limited epidemiological evaluation in the pallative treatment of a number of inflammatory conditions. The herb is particularly preferred on the American market due to its various uses for healing, which provides the impetus for this research. The herb is being used to treat osteoarthritis and claims have been made for its ability to: enhance the repair of deoxyribonucleic acid (DNA), support joint health and improve immune function, enable normal division of …

Animal Sentience And The Precautionary Principle, Jonathan Birch

Animal Sentience

In debates about animal sentience, the precautionary principle is often invoked. The idea is that when the evidence of sentience is inconclusive, we should “give the animal the benefit of the doubt” or “err on the side of caution” in formulating animal protection legislation. Yet there remains confusion as to whether it is appropriate to apply the precautionary principle in this context, and, if so, what “applying the precautionary principle” means in practice regarding the burden of proof for animal sentience. Here I construct a version of the precautionary principle tailored to the question of animal sentience together with a …

Cautions About Precautions, Jay R. Stauffer Jr.

Animal Sentience

Assuming an animal to be sentient in the absence of conclusive evidence to the contrary is an extreme position, hence it should not and could not be the default assumption. Birch explains how the precautionary principle may be used to substantiate decisions to give the animal the benefit of doubt. Although I am reluctant to accept all of his points, Birch has provided an excellent argument for the use of the precautionary principle for the detection of animal sentience. I agree that more research is needed to refine and understand this relationship.

The Multiple Facets Of Empathy, Magdalena Boch, Claus Lamm

Animal Sentience

We discuss the definition of empathy provided by Kujala (2017) and argue that research in this field, in assigning the cognitive component of empathy only a secondary role, misses crucial information. Further knowledge about dogs’ ability for higher cognitive processes helps (a) in interpreting results such as potential prosocial behavior in dogs and (b) sheds light on the question of whether abilities like perspective-taking and self-other distinction are uniquely human.