Digital Commons Network^™

A Socio-Technological Perspective Of Blended Problem-Based Learning, Roisin Donnelly

Other resources

No abstract provided.

Enabling Practitioners To Apply Elearning To Professional Development Practice, Roisin Donnelly

Other resources

No abstract provided.

The Effects Of Drought On Diets Of Apex Predators In The South African Lowveld Inferred By Fecal Hair Analysis, Shelby Wade

Mahurin Honors College Capstone Experience/Thesis Projects

To properly manage offtake quotas and conservation efforts, Balule Nature Reserve (South Africa) instituted a study in 2014 to determine prey species selection by megapredators. In 2015, Balule Nature Reserve received about 190 mm less rainfall between the months of January and June than in 2014 (116 mm less than average). This study compares the diets of lions and hyaenas between 2014 and 2015. Prey species consumed were determined by fecal analysis, and results were compared to prey availability. Sixteen, 1 km2 plots were chosen from the 400 km2 Reserve. Between June and August 2015, we walked three, 1 km …

Curriculum Subcommittee Agenda, September 1, 2016, Utah State University

Educational Policies Committee

Semester Course Approval Reviews

Program Proposals

• Changing the name from Agricultural Economics to Applied Economics
• Offering a Minor in Residential Landscape Design
• Adding a Forest Ecology Specialization to the MS and PhD programs of the Department of Wildland Resources

Other

• Approving Prerequisites
• Curriculog updates and site changes

State & Federal Religious Accommodation Bills: Overview Of The 2015-2016 Legislative Session, Public Rights/Private Conscience Project

Center for Gender & Sexuality Law

Since the Supreme Court’s 2015 decision in Obergefell v. Hodges, which held that laws limiting marriage to opposite-sex couples were unconstitutional, opponents of marriage equality and LGBT rights have largely turned their attention to the enactment of religious exemption laws. These exemptions allow individuals and organizations to violate certain federal, state, and local laws and regulations that conflict with their religious faith. While some proposed bills are state-level variations on the extremely broad and general federal Religious Freedom Restoration Act (RFRA), passed in 1993, a new variety of legislation provides narrower accommodations specifically relating to religious views about sex, …

2016 Annual Accountability Report, Clemson University

Accountability Reports

Clemson University's 2015-2016 Annual Accountability Report submitted to the South Carolina Budget and Control Board.

Systematic Review Of Veterans' Coping Strategies: How Can Rural Veterans Improve Their Quality Of Life?, Tracey Marie Barnett, Alexa Smith-Osborne, Freda Barnett-Braddock

Contemporary Rural Social Work Journal

This systematic review examines the empirical literature on an emerging body of coping strategies (CS), both civilian readjustment and health-risk related, experienced by United States military veterans exposed to combat stress and other military lifestyle stressors. Studies that met inclusion criteria were selected among quantitative, qualitative, and mixed-methods studies published in peer-reviewed journals. Population, Intervention, Comparison, and Outcome (PICO) criteria and Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) were applied to all studies. Seventeen reports meeting a priori inclusion criteria were extracted from 107 studies accessed through 9 electronic databases. Data were synthesized to investigate two research questions informing …

Reinventing Social Work Education And Service Delivery In Rural Areas: An Interdisciplinary Model For Serving Vulnerable Populations, Wayne R. Moore, Fran Pearson, John C. Rife, K. Jay Poole, Lelia S. Moore, Antonia M. Reaves

Contemporary Rural Social Work Journal

This article presents an interprofessional case study approach to serving the social service and health needs of vulnerable persons living rural communities. This project, the Congregational Social Work Education Initiative (CSWEI), is funded by a health care foundation. Persons in rural areas are often at risk for poverty, homelessness and lack of access to needed health and social services. The case study demonstrates the opportunities for collaboration between professional social work, religiously affiliated organizations (RAOs) and nursing in order to reduce health and mental health disparities among residents in rural areas.

Project Empower: An Innovative Approach To Community Behavioral Health Service Delivery, Saundra H. Starks, Elizabeth L. Jones, Suzie T. Cashwell, Karissa Stokes

Contemporary Rural Social Work Journal

Project EMPOWER was a grant funded initiative designed to positively impact a rural community by providing behavioral health services and case management to low-income families. An interdisciplinary service team comprised of behavioral health specialists and graduate level interns in the fields of social work, psychiatric nursing, and counseling worked to provide services under the supervision of a doctorate level clinical social work professor. Community partnerships were forged to increase opportunities for community members to have accessible, affordable services. Using an empowerment model rooted in systems and integrated practice, the services included assessments, referrals, group, individual and family counseling, child care, …

Book Review: Hard Living In America's Heartland: Rural Poverty In The 21st Century Midwest, Peter A. Kindle Ph.D.

Contemporary Rural Social Work Journal

Book Review: Hard Living in America's Heartland: Rural Poverty in the 21st Century Midwest Paula W. Dáil 2015 Jefferson, NC: McFarland 266 pages Softcover: $45.00 US ISBN-10: 0786474815 ISBN-13: 978-0-7864-7481-3

Rna-Binding Protein Fxr1 Regulates P21 And Terc Rna To Bypass P53-Mediated Cellular Senescence In Oscc, Mrinmoyee Majumder, Reniqua House, Nallasivam Palanisamy, Shuo Qie, Terrence A. Day, David Neskey, J A. Diehl, Viswanathan Palanisamy

Urology Articles

RNA-binding proteins (RBP) regulate numerous aspects of co- and post-transcriptional gene expression in cancer cells. Here, we demonstrate that RBP, fragile X-related protein 1 (FXR1), plays an essential role in cellular senescence by utilizing mRNA turnover pathway. We report that overexpressed FXR1 in head and neck squamous cell carcinoma targets (G-quadruplex (G4) RNA structure within) both mRNA encoding p21 (Cyclin-Dependent Kinase Inhibitor 1A (CDKN1A, Cip1) and the non-coding RNA Telomerase RNA Component (TERC), and regulates their turnover to avoid senescence. Silencing of FXR1 in cancer cells triggers the activation of Cyclin-Dependent Kinase Inhibitors, p53, increases DNA damage, and ultimately, cellular …

Understanding Fathers' Participation In Home Visits, Center For Human Services Research, University At Albany

Children, Family & Elder Services Reports and Research Briefs

Research shows the important role that fathers play in promoting healthy child development. In 2007, HFNY began a focused effort to promote the development of a father-inclusive culture and increase involvement of fathers in all aspects of home visiting.

Program data showed that HFNY was not adequately capturing fathers’ participation in home visits. Data collection forms and the management information system were therefore revised to collect more detailed information about fathers.

In 2015, the HFNY research team conducted analyses using this new information to learn more about how fathers are involved in HFNY.

Grants Report, September 2016, Grants And Foundation Relations, Illinois Wesleyan University

Reports

No abstract provided.

University Rankings: Evidence And A Conceptual Framework, Jonathan G.S. Koppell, Jacob Fowles, H. George Frederickson

Publications from President Jonathan G.S. Koppell

University ranking has high public visibility, the ranking business has flourished, and institutions of higher education have not been able to ignore it. This study of university ranking presents general considerations of ranking and institutional responses to it, particularly considering reactions to ranking, ranking as a self-fulfilling prophecy, and ranking as a means of transforming qualities into quantities. The authors present a conceptual framework of university ranking based on three propositions and carry out a descriptive statistical analysis of U.S. and international ranking data to evaluate those propositions. The first proposition of university ranking is that ranking systems are demarcated …

Geology Colloquium | Optimization And Analysis Of A Slow-Release Permanganate Gel For Dilute Dnapl Plume Remediation In Groundwater, Sept. 23, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Use Of In Silico Structure Activity Relationship (Sar) Project In Medicinal Chemistry Course At Winona State University: Molecular Docking Simulation And Analysis Of Human Dopamine D3 Receptor-Rotigotine Analog Binding, Thomas Provost, Myoung Lee

Student Research and Creative Projects 2016-2017

Medicinal Chemistry is a course offered by Winona State University that focuses on the chemical structure - biological activity relationship (SAR). The course is offered to chemistry and biology students who have previously taken organic chemistry and intend to further their knowledge of pharmacokinetics and pharmacodynamics. Project-based learning utilizing in silico molecular docking simulations is a primary method to help students actively learn the concept and the application of the SAR in medicinal chemistry. A drug target with a known three-dimensional structure is chosen and the amino acid residues at the binding site of the protein structure were analyzed. A …

Attempted Synthesis Of Ergosta-5, 22, 24(28)-Trienol Starting With Stigmasterol, Matthew Worke

Student Research and Creative Projects 2016-2017

This project was an attempt to synthesize ergosta-5, 22, 24(28)-trienol to help confirm the structure of an unknown sterol found in dried morel mushrooms i n previous research conducted by Dr. Nalli's lab. Unfortunately three attempts at the first step of the sy nthesis were al l unsuccessful and the project was aborted.

Winona Currents Magazine, University Advancement - Winona State University

Winona Currents

This magazine published by Winona State University’s University Advancement was intended to inform WSU Alumni, students, faculty, staff and the greater community about Alumni and the university. The cover theme is: A Hero's Homecoming 2016.

Forgiveness, Blame, And Punishment, James Staihar

Buffalo Public Interest Law Journal

When someone commits a crime with no exculpatory defenses,he is blameworthy and deserves to be punished. Nevertheless, assuming the criminal were to satisfy some conditions, he could become forgivable. In this Essay I defend a restorative theory of what it means to forgive a criminal and when the forgiveness of a criminal would be warranted. My defense is unique in that I ultimately derive my theory offorgiveness from a novel theory of when criminals deserve to be punished. My restorative theory of forgiveness yields at least two general insights that are generally not appreciated in the prior literature on forgiveness. …

The Ties That Bind: Attachment Theory And Child Welfare—Considering The Benefits Of Maintaining Biological Connections For Children In Foster Care, Keli Iles-Hernandez

Buffalo Public Interest Law Journal

No abstract provided.

Table Of Contents, Buffalo Public Interest Law Journal

Buffalo Public Interest Law Journal

No abstract provided.

Identification Of Pathway-Specific Serum Biomarkers Of Response To Glucocorticoid And Infliximab Treatment In Children With Inflammatory Bowel Disease, Christopher R. Heier, Alyson A. Fiorillo, Ellen Chaisson, Heather A. Gordish-Dressman, Yetrib Hathout, Jesse M. Damsker, Eric P. Hoffman, Laurie S. Conklin

Genomics and Precision Medicine Faculty Publications

Objective:

Serum biomarkers may serve to predict early response to therapy, identify relapse, and facilitate drug development in inflammatory bowel disease (IBD). Biomarkers are particularly important in children, in whom achieving early remission and minimizing procedures are especially beneficial.

Methods:

We profiled protein and micro RNA (miRNA) in serum from patients pre- and post-therapy, to identify molecular markers of pharmacodynamic effect. Serum was obtained from children with IBD before and after treatment with either corticosteroids (prednisone; n=12) or anti-tumor necrosis factor-α biologic (infliximab; n=7). Over 1,100 serum proteins were assayed using aptamer-based SOMAscan proteomics, and 22 miRNAs analyzed …

Muscle Myeloid Type I Interferon Gene Expression May Predict Therapeutic Responses To Rituximab In Myositis Patients., Kanneboyina Nagaraju, Svetlana Ghimbovschi, Sree Rayavarapu, Aditi Phadke, Lisa G. Rider, Eric P. Hoffman, Frederick Miller

Genomics and Precision Medicine Faculty Publications

Objective. To identify muscle gene expression patterns that predict rituximab responses and assess the effects of rituximab on muscle gene expression in PM and DM.

Methods. In an attempt to understand the molecular mechanism of response and non-response to rituximab therapy, we performed Affymetrix gene expression array analyses on muscle biopsy specimens taken before and after rituximab therapy from eight PM and two DM patients in the Rituximab in Myositis study. We also analysed selected muscle-infiltrating cell phenotypes in these biopsies by immunohistochemical staining. Partek and Ingenuity pathway analyses assessed the gene pathways and networks.

Results. Myeloid type I IFN …

Irisin Lowers Blood Pressure By Improvement Of Endothelial Dysfunction Via Ampk‐Akt‐Enos‐No Pathway In The Spontaneously Hypertensive Rat, Jinjuan Fu, Yu Han, Jialiang Wang, Yukai Liu, Shuo Zeng, Lin Zhou, Pedro A. Jose, Chunyu Zeng

Medicine Faculty Publications

Background Exercise is a major nonpharmacological treatment for hypertension, but its underlying mechanisms are still not completely elucidated. Irisin, a polypeptide containing 112 amino acids, which is secreted mainly by skeletal muscle cells during exercise, exerts a protective role in metabolic diseases, such as diabetes mellitus and obesity. Because of the close relationship between irisin and metabolic diseases, we hypothesized that irisin may play a role in the regulation of blood pressure.

Methods and Results Blood pressures of male Wistar‐Kyoto (WKY) rats and spontaneously hypertensive rats (SHRs) were monitored through the carotid artery. Our study found that acute intravenous injection …

Variation In The Glucose Transporter Gene Slc2a2 Is Associated With Glycemic Response To Metformin, Kaixin Zhou, Sook-Wah Yee, Eric L. Seiser, Nienke Van Leeuwen, Roger Tavendale, Amanda J. Bennett, Christopher J. Groves, Ruth L. Coleman, Amber A. Van Der Heijden, Joline W. Beulens, Catherine E. De Keyser, Linda Zaharenko, Daniel M. Rotroff, Mattijs Out, Kathleen A. Jablonski, Ling Chen, Martin Javorský, Jozef Židzik, Albert M. Levin, Keoki L. Williams, Tanja Dujic, Sabina Semiz, Michiaki Kubo, Huan-Chieh Chien, Shiro Maeda, John S. Witte, Longyang Wu, Ivan Tkáč, Adriaan Kooy, Ron Hn Van Schaik, Coen Da Stehouwer, Lisa Logie, Calum Sutherland, Janis Klovins, Valdis Pirags, Albert Hofman, Bruno H Stricker, Alison A Motsinger-Reif, Michael J Wagner, Federico Innocenti, Leen M 'T Hart, Rury R Holman, Mark I Mccarthy, Monique M Hedderson, Colin N A Palmer, Jose C Florez, Kathleen M Giacomini, Ewan R Pearson

Internal Medicine Articles

Metformin is the first-line antidiabetic drug with over 100 million users worldwide, yet its mechanism of action remains unclear. Here the Metformin Genetics (MetGen) Consortium reports a three-stage genome-wide association study (GWAS), consisting of 13,123 participants of different ancestries. The C allele of rs8192675 in the intron of SLC2A2, which encodes the facilitated glucose transporter GLUT2, was associated with a 0.17% (P = 6.6 × 10(-14)) greater metformin-induced reduction in hemoglobin A1c (HbA1c) in 10,577 participants of European ancestry. rs8192675 was the top cis expression quantitative trait locus (cis-eQTL) for SLC2A2 in 1,226 human liver samples, suggesting a key role …

Geology Colloquium | Epa And Mckay Present Their Research, Sept. 9, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Geology Colloquium | Field Mapping The Outer Margin Of Serpent Mound, Sept. 16, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Science Café | Symmetries In Nature A Key To The Subatomic World, Sept. 7, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Roosenburg Quoted On Terrapin Business Risk Of Poaching, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Methane Emissions From Global Rice Fields: Magnitude, Spatiotemporal Patterns, And Environmental Controls, Bowen Zhang, Hanqin Tian, Wei Ren, Bo Tao, Chaoqun Lu, Jia Yang, Kamaljit Banger, Shufen Pan

Plant and Soil Sciences Faculty Publications

Given the importance of the potential positive feedback between methane (CH₄) emissions and climate change, it is critical to accurately estimate the magnitude and spatiotemporal patterns of CH₄ emissions from global rice fields and better understand the underlying determinants governing the emissions. Here we used a coupled biogeochemical model in combination with satellite-derived contemporary inundation area to quantify the magnitude and spatiotemporal variation of CH₄ emissions from global rice fields and attribute the environmental controls of CH₄ emissions during 1901–2010. Our study estimated that CH₄ emissions from global rice fields varied from 18.3 ± …