Digital Commons Network^™

Characteristics And Products Of The Reductive Degradation Of 3-Nitro-1,2,4-Triazol-5-One (Nto) And 2,4-Dinitroanisole (Dnan) In A Fe-Cu Bimetal System, Elsie Kitcher, Washington Braida, Agamemnon Koutsospyros, Julius Pavlov, Tsang-Liang Su

Civil Engineering Faculty Publications

It has been shown previously that, under acidic conditions, 3-nitro-1,2,4-triazol-5-one (NTO) and 2,4-dinitroanisole (DNAN) degrade in the presence of iron/copper bimetal particles; the reactions can be modeled by pseudo-first-order kinetics. This study investigates the reaction mechanisms of the degradation processes under different conditions. Batch studies were conducted using laboratory-prepared solutions and an industrial insensitive munition-laden (IMX) wastewater. The influence of parameters such as initial pH of the solution, copper/iron (Fe-Cu) contact, and solid/liquid ratio were systematically investigated to assess their impact on the reaction kinetics. These parameters were subsequently incorporated into pseudo-first-order decomposition models for NTO and DNAN. The activation …

Research Support Study: Agriculture; University Of Connecticut Local Report, Carolyn V. Mills, Sharon Giovenale

Published Works

The local University of Connecticut report of a 19 institution ethnographic agriculture research support study done with Ithaka S+R.

Photothermal Therapy Improves The Efficacy Of A Mek Inhibitor In Neurofibromatosis Type 1-Associated Malignant Peripheral Nerve Sheath Tumors., Elizabeth E. Sweeney, Rachel A. Burga, Chaoyang Li, Yuan Zhu, Rohan Fernandes

Pediatrics Faculty Publications

Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive tumors with low survival rates and the leading cause of death in neurofibromatosis type 1 (NF1) patients under 40 years old. Surgical resection is the standard of care for MPNSTs, but is often incomplete and can generate loss of function, necessitating the development of novel treatment methods for this patient population. Here, we describe a novel combination therapy comprising MEK inhibition and nanoparticle-based photothermal therapy (PTT) for MPNSTs. MEK inhibitors block activity driven by Ras, an oncogene constitutively activated in NF1-associated MPNSTs, while PTT serves as a minimally invasive method to ablate …

An Integrated Risk And Vulnerability Assessment Framework For Climate Change And Malaria Transmission In East Africa, Esther Achieng Onyango, Oz Sahin, Alex Awiti, Cordia Chu, Brendan Mackey

East Africa Institute

Background: Malaria is one of the key research concerns in climate change-health relationships. Numerous risk assessments and modelling studies provide evidence that the transmission range of malaria will expand with rising temperatures, adversely impacting on vulnerable communities in the East African highlands. While there exist multiple lines of evidence for the influence of climate change on malaria transmission, there is insufficient understanding of the complex and interdependent factors that determine the risk and vulnerability of human populations at the community level. Moreover, existing studies have had limited focus on the nature of the impacts on vulnerable communities or how well …

Um Student Spreads Message Of Hope With Book On Disabilities, Christina Steube

University of Mississippi News

Michael Deauville to sign copies in the Grove before Ole Miss-MSU game

November 11, 2016 Finance & Facilities (F&F) Committee Meeting, Evp For Administration

Finance and Facilities Committee

Documents related to the November 11, 2016 Board of Regents' Finance and Facilities Committee Meeting. (Agenda, Minutes, eBook, Notice)

Is Group Therapy Democratic? Enduring Consequences Of Outward Bound’S Alignment With The Human Potential Movement, Jayson O. Seaman

Kinesiology

Franklin Vernon provided an example of how programs viewing themselves as “cultural islands” are in fact embedded within historical capitalist relations, through the discourses of self that they promote. In this response, I expand on Vernon’s argument to situate the quasi-therapeutic practices he identified in the history of the human potential movement, which effectively merged with Outward Bound starting in the 1960s and continues to define outdoor experiential education. Where Vernon sought the structural referents to different models of self, this response seeks their historical origins. The response concludes by linking Vernon’s argument with existing critiques and parallel efforts in …

Winter Activity Of Coastal Plain Populations Of Bat Species Affected By White-Nose Syndrome And Wind Energy Facilities, John F. Grider, Angela L. Larsen, Jessica A. Homyack

KIP Articles

Across the entire distribution of a species, populations may have variable responses to environmental perturbations. Many bat species experience mortality in large portions of their range during hibernation and along migratory paths to and from wintering grounds, from White-nose syndrome (WNS) and wind energy development, respectively. In some areas, warm temperatures may allow bats to remain active through winter, thus decreasing their susceptibility to WNS and/or mortality associated with migration to wintering grounds. These areas could act as a refugia and be important for the persistence of local populations. To determine if warmer temperatures affect bat activity, we compared year-round …

Rodgers & Hammerstein's Oklahoma!

Taylor Theatre Playbills

The playbill for Taylor University’s performance of Oklahoma!. Books and lyrics by Oscar Hammerstein II, music by Richard Rogers.

Performed on November 11-13, 18-20, 2016 at the Mitchell Theatre.

The high-spirited rivalry between the farmers and cowmen of the Western Indian Territory provides the colorful, turn-of-the-century backdrop for Curley and Laurey’s love story. But with these headstrong romantics holding the reins, the road to love is as bumpy as a surrey ride down a dusty road. Despite many hardships, their rocky romance leads to a new life beginning in a brand new state. Rodgers & Hammerstein's first collaboration remains, …

Estimating Propensity Parameters Using Google Pagerank And Genetic Algorithms, David Murrugarra, Jacob Miller, Alex N. Mueller

Mathematics Faculty Publications

Stochastic Boolean networks, or more generally, stochastic discrete networks, are an important class of computational models for molecular interaction networks. The stochasticity stems from the updating schedule. Standard updating schedules include the synchronous update, where all the nodes are updated at the same time, and the asynchronous update where a random node is updated at each time step. The former produces a deterministic dynamics while the latter a stochastic dynamics. A more general stochastic setting considers propensity parameters for updating each node. Stochastic Discrete Dynamical Systems (SDDS) are a modeling framework that considers two propensity parameters for updating each node …

Volume Cxxxiv, Number 9, November 11, 2016, Lawrence University

The Lawrentian

No abstract provided.

Genome Of The Asian Longhorned Beetle (Anoplophora Glabripennis), A Globally Significant Invasive Species, Reveals Key Functional And Evolutionary Innovations At The Beetle-Plant Interface, Duane D. Mckenna, Erin D. Scully, Yannick Pauchet, Kelli Hoover, Roy Kirsch, Scott M. Geib, Robert F. Mitchell, Robert M. Waterhouse, Seung-Joon Ahn, Deanna Arsala, Joshua B. Benoit, Heath Blackmon, Tiffany Bledsoe, Julia H. Bowsher, André Busch, Bernarda Calla, Hsu Chao, Anna K. Childers, Christopher Childers, Dave J. Clarke, Lorna Cohen, Jeffery P. Demuth, Huyen Dinh, Harshavardhan Doddapaneni, Amanda Dolan, Jian J. Duan, Shannon Dugan, Markus Friedrich, Karl M. Glastad, Michael A. D. Goodisman, Stephanie Haddad, Yi Han, Daniel S. T. Hughes, Panagiotis Ioannidis, J. Spencer Johnston, Jeffery W. Jones, Leslie A. Kuhn, David R. Lance, Chien-Yueh Lee, Sandra L. Lee, Han Lin, Jeremy A. Lynch, Armin P. Moczek, Shwetha C. Murali, Donna M. Muzny, David R. Nelson, Subba R. Palli, Kristen A. Panfilio, Dan Pers, Monica F. Poelchau, Honghu Quan, Jiaxin Qu, Ann M. Ray, Joseph P. Rinehart, Hugh M. Robertson, Richard Roehrdanz, Andrew J. Rosendale, Seunggwan Shin, Christian Silva, Alex S. Torson, Iris M. Vargas Jentzsch, John H. Werren, Kim C. Worley, George Yocum, Evgeny M. Zdobnov, Richard A. Gibbs, Stephen Richards

Entomology Faculty Publications

Background: Relatively little is known about the genomic basis and evolution of wood-feeding in beetles. We undertook genome sequencing and annotation, gene expression assays, studies of plant cell wall degrading enzymes, and other functional and comparative studies of the Asian longhorned beetle, Anoplophora glabripennis, a globally significant invasive species capable of inflicting severe feeding damage on many important tree species. Complementary studies of genes encoding enzymes involved in digestion of woody plant tissues or detoxification of plant allelochemicals were undertaken with the genomes of 14 additional insects, including the newly sequenced emerald ash borer and bull-headed dung beetle.

Results: …

Seniors Welcome! Avoiding The Trap Of Age Limits In Health Research, Arshad Jahangir

Journal of Patient-Centered Research and Reviews

The guest editor introduces this specialty issue of the Journal of Patient-Centered Research and Reviews, which focuses on cardiovascular diseases in the elderly. The reality of an aging population has increased the need for better evidence-based medicine in older patients. However, randomized controlled trials frequently exclude such patients, especially those with comorbidities, from study. This practice ignores the fact that physiologic changes to the cardiovascular system caused by the aging process and aging-associated diseases create clinical dilemmas distinct from those in younger patients. Considering the rising costs of health care and growing incidence of cardiovascular disease, research efforts and …

Tgf-Β1 Increases Resistance Of Nih/3t3 Fibroblasts Toward Apoptosis Through Activation Of Smad2/3 And Erk1/2 Pathways, Ulugbek Negmadjanov, Alisher Holmuhamedov, Larisa Emelyanova, Hao Xu, Farhan Rizvi, Gracious R. Ross, A. Jamil Tajik, Yang Shi, Ekhson Holmuhamedov, Arshad Jahangir

Journal of Patient-Centered Research and Reviews

Purpose

Excessive fibrosis has been suggested to result from persistence of fibroblasts in injured tissue due to impaired apoptosis, but signaling pathways are not fully defined.

Methods

Suppression of apoptotic cell death following transforming growth factor-β1 (TGF-β1) exposure was studied using the culture of NIH/3T3 mouse embryonic fibroblasts. Caspase-3 activity, propidium iodide staining and annexin V binding induced by Fas-ligand (FasL) in NIH/3T3 fibroblasts in the absence and presence of TGF-β1 was determined, and relative contribution of signaling through Smad2/3 and noncanonical Erk1/2 and Akt pathways was dissected by assessing phosphorylation status of these kinases and caspase activity in the …

Functional Alterations Of Ion Channels From Cardiac Fibroblasts In Heart Diseases, Gracious R. Ross, Arshad Jahangir

Journal of Patient-Centered Research and Reviews

In an aged population, cardiovascular disease is the leading cause of fatality and morbidity. Age-related fibrotic remodeling of the heart contributes to progressive myocardial dysfunction. Cardiac fibroblasts (CF), responsible for the maintenance of extracellular matrix and fibrosis process, play an important role in cardiac health and disease. CFs influence myocardial function by their chemical, electrical and mechanical interactions with cardiomyocytes through extracellular matrix deposition or secretion of cytokines and growth factors. These, in turn, are modulated by ion channels, macromolecular pores in the plasma membrane that allow selective ionic fluxes of major ions like K⁺, Ca²⁺, …

Chimes: November 11, 2016, Calvin College

Chimes

Israeli scientists make breakthrough in HIV cure by Victor Lynde

Founder of Detroit Dirt gives lecture about composting by Courtney Zonnefeld

Professors discuss economic issues facing next president by Matt Leistra

International Education Week celebrates multiculturalism by Katie Ulrich

Men's basketball team prepares for new season by Mark Peless

Marvel's "Doctor Strange" marvels by Brandon Schreur

The Rhetoric of the Rhetoric Center by Michelle Hofman

The 2016 Stormwater Bill: An Analysis Of Perceived And Real Problems With Proposed Solutions, Jonathon R. Lubrano, Elizabeth A. Andrews, Roy A. Hoagland

Virginia Coastal Policy Center

No abstract provided.

Survey Of The Heritability And Sparse Architecture Of Gene Expression Traits Across Human Tissues., Heather E. Wheeler, Kaanan P. Shah, Jonathon Brenner, Tzintzuni Garcia, Keston Aquino-Michaels, Gtex-Consortium, Nancy J. Cox, Dan L. Nicolae, Hae Kyung Im

Bioinformatics Faculty Publications

Understanding the genetic architecture of gene expression traits is key to elucidating the underlying mechanisms of complex traits. Here, for the first time, we perform a systematic survey of the heritability and the distribution of effect sizes across all representative tissues in the human body. We find that local h² can be relatively well characterized with 59% of expressed genes showing significant h² (FDR < 0.1) in the DGN whole blood cohort. However, current sample sizes (n ≤ 922) do not allow us to compute distal h². Bayesian Sparse Linear Mixed Model (BSLMM) analysis provides strong evidence that the genetic contribution to local expression traits is dominated by …

Advanced Feature Extraction And Dimensionality Reduction For Unmanned Underwater Vehicle Fault Diagnosis, Wathiq Abed, Riccardo Polvara, Yogang Singh, Sanjay Sharma, Robert Sutton, Daniel Hatton, Andrew Manning, Jian Wan

School of Engineering, Computing and Mathematics

No abstract provided.

November 11, 2016 Special Issue, The Daily Mississippian

Daily Mississippian (all digitized issues)

Investiture of Chancellor Jeffrey S. Vitter

Wings Outstretched: New Contributions In Undergraduate Research

PSU McNair Scholars Online Journal

No abstract provided.

Polymer Systems For Controlled Release Of Lentivectors, Eduardo Silva

Amgen Seminar Series in Chemical Engineering

We target vascularization as a critical enabling technology to engineer or regenerate virtually any tissue or organ system. One important target for new therapies is peripheral artery disease (PAD). Current therapies for PAD aim to reduce risk with lifestyle changes, antiplatelet drugs, and statins before intervening surgically with either bypass or endovascular revascularization. However, for those patients who fail to respond to first-line therapies, the manifestations of PAD include critical limb ischemia (CLI). Staggeringly, ~25% of CLI patients will likely die within a year of the initial treatment. Despite positive results with animal studies and small-scale clinical studies, large clinical …

Relationship Between Library Anxiety And Attitudes Toward Computer Based On An Integrated Model Of Atc And Belcat Of Public Libraries’ Users, Mohammad Reza Farhadpoor

Library Philosophy and Practice (e-journal)

Abstract

Purpose: the present study evaluated the relationship between library anxiety and attitude toward computer based on as integrated model of ATC and BELCAT of public libraries’ user.

Methodology: the study was conducted using the analytic survey. A sample of 370 participants was randomly selected out of 10757 users of public libraries in Dezful city, Khouzestan, Iran. To collect data for library anxiety, Bostick questionnaire and for computer attitude a questionnaire based on ATC and BELCAT models were used.

Findings: the results showed that the most important factor of distress based on the scale of Bostick was"the …

Climate Change Adaptation Case Study: Benefit-Cost Analysis Of Coastal Flooding Hazard Mitigation, Will Cooper, Federico Garcia, Diana Pape, David Ryder, Ben Witherell

Journal of Ocean and Coastal Economics

The damage Hurricane Sandy caused had far-reaching repercussions up and down the East Coast of the United States. Vast coastal flooding accompanied the storm, inundating homes, businesses, and utility and emergency facilities. Since the storm, projects to mitigate similar future floods have been scrutinized. Such projects not only need to keep out floodwaters but also be designed to withstand the effect that climate change might have on rising sea levels and increased flood risk.

In this study, we develop an economic model to assess the costs and benefits of a berm (sea wall) to mitigate the effects of flooding from …

How Do Faculty At The University Of New Mexico Use Humor In Online Teaching, John T. Granato

Organization, Information and Learning Sciences ETDs

Humor is a ubiquitous experience that facilitates learning, social coordination and wellbeing. This study examined how the faculty at the University of New Mexico used humor in its online courses. The process involved faculty interviews, a focus group of instructional online designers, questionnaires and documentation to collect data, and then used thematic analysis and code development to arrive at its findings. The study found that the humor pedagogy at the University of New Mexico has fallen into disuse for online courses because of (1) a hesitation (fear) to use humor, (2) fear of what students would think, and (3), hesitation …

Neural Correlates Of The Development Of Cognitive Flexibility, Dina R. Dajani

Open Access Theses

One aspect of executive function, cognitive flexibility, is necessary for implementing the appropriate and efficient adaptation of cognitions in the face of changing environments. In a recently proposed framework, cognitive flexibility is thought to involve multiple component functions: stimulus-driven attention and two related executive functions, working memory and inhibition. These executive functions commonly recruit the frontal, cingulate, and parietal brain regions, but it is unclear whether cognitive flexibility and its component functions arise from specific connectivity profiles within this superordinate fronto-cingulo-parietal network. The objectives of this study were to 1) index behavioral changes in attention, working memory, inhibition and cognitive …

11-10-2016 Two Swosu Students Accepted For Early Admission To Vet School, Southwestern Oklahoma State University

THE BARK ARCHIVE 2016

Two Southwestern Oklahoma State University students majoring in biology have been selected for early admission to the Oklahoma State University Doctor in Veterinary Medicine Program.

Intellectual Life Grant Recipients Announced, Alexis H. Sarkisian

Library 411

No abstract provided.

The Setonian, November 10, 2016, Seton Hall University

2016

No abstract provided.

November Agenda, Wku Graduate Council

Graduate School

Meeting agenda.