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2016

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Synthesis And Characterization Of Silver Nanoparticles Integrated In Polyvinyl Alcohol Nanofibers For Bionanotechnological Applications, Gamze Tan, Semran Sağlam, Ezgi̇ Emül, Demet Erdönmez, Necdet Sağlam Jan 2016

Synthesis And Characterization Of Silver Nanoparticles Integrated In Polyvinyl Alcohol Nanofibers For Bionanotechnological Applications, Gamze Tan, Semran Sağlam, Ezgi̇ Emül, Demet Erdönmez, Necdet Sağlam

Turkish Journal of Biology

Characterization and microbial growth activity of polyvinyl alcohol (PVA) nanofibers (NFs) produced by an electrospinning technique containing different amounts of silver nanoparticles (AgNPs) was investigated. AgNPs were synthesized by chemical reduction of silver nitrate (AgNO3) (in different weight ratios) in PVA solution followed by electrospinning to produce PVA/AgNPs NFs. The properties of PVA/AgNPs NFs were studied as a function of the silver content. The morphology and distribution of NFs and AgNPs were characterized by transmission and scanning electron microscopy. The size of NFs was 135-160 nm, and the size of AgNPs was 15-27 nm. TEM images clearly showed that spherical …


Cytotoxicity And Antiviral Activity Of Palladium(Ii) And Platinum(Ii) Complexes With 2-(Diphenylphosphino)Benzaldehyde 1-Adamantoylhydrazone, Vera Simic, Stoimir Kolarevic, Ilija Brceski, Dejan Jeremic, Branka Vukovic-Gacic Jan 2016

Cytotoxicity And Antiviral Activity Of Palladium(Ii) And Platinum(Ii) Complexes With 2-(Diphenylphosphino)Benzaldehyde 1-Adamantoylhydrazone, Vera Simic, Stoimir Kolarevic, Ilija Brceski, Dejan Jeremic, Branka Vukovic-Gacic

Turkish Journal of Biology

Metal coordination compounds have an important role in the development of novel drugs. Using the resazurin microtitration assay we assessed the cytotoxicity and antiviral activity of the ligand 2-(diphenylphosphino)benzaldehyde 1-adamantoylhydrazone and its Pd(II) and Pt(II) complexes. Cytotoxicity was tested in A549 human lung adenocarcinoma epithelial cells. We observed that the ligand displayed a more pronounced cytotoxic activity than the platinum-based drug, carboplatin. Morphological evaluation of A549 cells treated with the ligand by acridine orange and ethidium bromide double staining revealed the presence of signs of apoptosis. Antiviral activity against poliovirus type 1 was assessed by examination of the cytopathic effect …


The Global Transcriptional Response Of A Raw Starch-Degrading Amylolytic Saccharomyces Cerevisiae Strain To Oxygen Limitation And Genetic Modification, Ceyda Kasavi̇, Serpi̇l Eraslan, Ebru Toksoy Öner, Betül Kirdar Jan 2016

The Global Transcriptional Response Of A Raw Starch-Degrading Amylolytic Saccharomyces Cerevisiae Strain To Oxygen Limitation And Genetic Modification, Ceyda Kasavi̇, Serpi̇l Eraslan, Ebru Toksoy Öner, Betül Kirdar

Turkish Journal of Biology

This study investigates the global transcriptional response of Saccharomyces cerevisiae strain WTPB-G, which was developed by transforming laboratory strain FY23 with the pPB-G plasmid expressing the Bacillus subtilis α-amylase and the Aspergillus awamori glucoamylase as a fusion protein. Genome-wide analysis of transcript levels revealed the cellular mechanisms and the related pathways that were affected by the genetic modification, which conferred the ability of starch utilization to wild-type cells by the introduction of a plasmid-harboring gene encoding the amylolytic activity. Fermentations were carried out in media containing glucose as the only carbon source under aerated and microaerated conditions, and the effect …


Frequency Of Twelve Carcinogenic Human Papilloma Virus Types Among Women From The South Backa Region, Vojvodina, Serbia, Gordana Kovacevic, Natasa Nikolic, Aleksandra Jovanovic-Galovic, Ivana Hrnjakovic-Cvjetkovic, Dusan Vuleta, Aleksandra Patic, Jelena Radovanov, Vesna Milosevic Jan 2016

Frequency Of Twelve Carcinogenic Human Papilloma Virus Types Among Women From The South Backa Region, Vojvodina, Serbia, Gordana Kovacevic, Natasa Nikolic, Aleksandra Jovanovic-Galovic, Ivana Hrnjakovic-Cvjetkovic, Dusan Vuleta, Aleksandra Patic, Jelena Radovanov, Vesna Milosevic

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to determine the presence and age distribution of different oncogenic human papilloma virus (HPV) types in women in the South Backa region and its relationship to Pap results. Materials and methods: In a group of 1087 women with normal and abnormal cytology, the commercial HR HPV Real-TM kit (Sacace Biotechnologies, Italy) was used. Results: Overall, 50.5% of the women were HPV positive. The presence of HPV types 18, 31, 51, and 58 was significantly influenced by age, while the presence of HPV types 16 and 45 was significantly influenced by cervical cytology. Results …


Effects And Mechanisms Of Curcumin On The Hemodynamic Variablesof Isolated Perfused Rat Hearts, Erkan Kilinç, Zi̇ya Kaygisiz, Bedri̇ Seli̇m Benek, Kenan Gümüşteki̇n Jan 2016

Effects And Mechanisms Of Curcumin On The Hemodynamic Variablesof Isolated Perfused Rat Hearts, Erkan Kilinç, Zi̇ya Kaygisiz, Bedri̇ Seli̇m Benek, Kenan Gümüşteki̇n

Turkish Journal of Medical Sciences

Background/aim: There is no information on the dose-response relationship of curcumin on the hemodynamic variables of the heart at the organ level in isolated perfused rat hearts. We aimed to investigate the effects and mechanisms of curcumin on the hemodynamic variables of isolated perfused rat hearts. Materials and methods: Rats were randomly divided into 9 groups. The isolated rat heart was retrogradely perfused with modified Krebs-Henseleit solution. After the stabilization period, each group was administered one of the following treatments for 25 min: saline, dimethyl sulfoxide, and curcumin (0.2 μM, 1 μM, and 5 μM); atropine (1 μM); atropine (1 …


Chronic Liver Diseases And Iron: A Concise Review With Emphasis On Hypotransferrinemia And Hypohepcidinemia, Naci̇ye Şemnur Büyükaşik, Yahya Büyükaşik Jan 2016

Chronic Liver Diseases And Iron: A Concise Review With Emphasis On Hypotransferrinemia And Hypohepcidinemia, Naci̇ye Şemnur Büyükaşik, Yahya Büyükaşik

Turkish Journal of Medical Sciences

No abstract provided.


The Relationship Of Mean Platelet Volume With Retinopathy In Type 2 Diabetes Mellitus, Asli Araz Güngör, Gül Gürsoy, Fati̇h Güngör, Seyi̇t Murat Bayram, Eray Atalay Jan 2016

The Relationship Of Mean Platelet Volume With Retinopathy In Type 2 Diabetes Mellitus, Asli Araz Güngör, Gül Gürsoy, Fati̇h Güngör, Seyi̇t Murat Bayram, Eray Atalay

Turkish Journal of Medical Sciences

Background/aim: Patients with diabetes mellitus have an increased risk of developing micro- and macrovascular complications. Retinopathy is one of the most important complications of diabetes whose pathophysiological cause has not yet been determined. One candidate may be platelet volume. In this study we aimed to investigate the association between mean platelet volume and diabetic retinopathy. Materials and methods: Mean platelet volume levels were investigated in type 2 diabetic patients with and without retinopathy, and in healthy participants. After reclassifying our diabetics in terms of the presence or absence of hypertension and hyperlipidemia, we compared their mean platelet volumes. We then …


The Role Of Apelin In The Assessment Of Response To Chemotherapyand Prognosis In Stage 4 Nonsmall Cell Lung Cancer, Si̇nem Özsari, Gürsel Çok, Ali̇ Veral, Ti̇mur Köse Jan 2016

The Role Of Apelin In The Assessment Of Response To Chemotherapyand Prognosis In Stage 4 Nonsmall Cell Lung Cancer, Si̇nem Özsari, Gürsel Çok, Ali̇ Veral, Ti̇mur Köse

Turkish Journal of Medical Sciences

Background/aim: Prediction of response to chemotherapy and prognosis bears clinical significance in patients with lung cancer. The aim of the study was to examine the association between apelin expression in tumor tissues and overall survival, progression-free survival, chemoresistance, and treatment response in stage 4 nonsmall cell lung cancer (NSCLC) patients undergoing chemotherapy. Materials and methods: A total of 81 patients who received chemotherapy due to a biopsy-documented diagnosis of NSCLC between 2004 and 2011 were retrospectively studied. Bronchoscopic biopsy samples were examined immunohistochemically. Results: Of the overall study population (n = 81), the mean age was 59.0 ± 9.2 years; …


Differentiated Thyroid Cancer In Patients With Prolactinoma, Abbas Ali̇ Tam, Cafer Kaya, Cevdet Aydin, Reyhan Ersoy, Beki̇r Çakir Jan 2016

Differentiated Thyroid Cancer In Patients With Prolactinoma, Abbas Ali̇ Tam, Cafer Kaya, Cevdet Aydin, Reyhan Ersoy, Beki̇r Çakir

Turkish Journal of Medical Sciences

Background/aim: Increasing evidence is available about the role of prolactin in the development of various cancers. The purpose of this study is to evaluate the frequency of thyroid cancer in patients with prolactinoma followed at a single site. Materials and methods: The medical records of 182 patients diagnosed with prolactinoma were reviewed retrospectively. Serum prolactin, antithyroglobulin, antithyroid peroxidase antibody, thyroid-stimulating hormone, free T4, and free T3 values and pituitary gland magnetic resonance imaging and thyroid ultrasound reports were evaluated. Results: Forty-five (39.5%) patients were found to have a thyroid nodule (13 solitary, 32 multiple). Ten patients were administered a thyroidectomy, …


Examination Of Factors Affecting Women?S Barrier Perception To Participate In Breast Cancer Screenings In A Region Affiliated With A Family Health Center In Turkey, Fatma Ersi̇n, Peri̇han Polat Jan 2016

Examination Of Factors Affecting Women?S Barrier Perception To Participate In Breast Cancer Screenings In A Region Affiliated With A Family Health Center In Turkey, Fatma Ersi̇n, Peri̇han Polat

Turkish Journal of Medical Sciences

Background/aim: This study was conducted in order to determine the factors related to women's barrier perception to participate in breast cancer screenings in a region affiliated with a family health center. Materials and methods: The study was a cross-sectional study. The sample group of the study consisted of 300 women. Descriptive statistics, t test, and Mann-Whitney U test were performed for the analysis of the data. Results: Breast self-examination (BSE) and mammography barrier perception mean score of those who were illiterate in terms of educational status, and BSE and mammography barrier perception mean score of those who were single in …


Neurological Outcome After Cardiac Arrest: A Prospective Study Of The Predictive Ability Of Prognostic Biomarkers Neuron-Specific Enolase, Glial Fibrillary Acidic Protein, S-100b, And Procalcitonin, Gülay Ok, Demet Aydin, Koray Erbüyün, Canan Gürsoy, Fatma Taneli̇, Sema Bi̇lge, Gönül Di̇nç Horasan Jan 2016

Neurological Outcome After Cardiac Arrest: A Prospective Study Of The Predictive Ability Of Prognostic Biomarkers Neuron-Specific Enolase, Glial Fibrillary Acidic Protein, S-100b, And Procalcitonin, Gülay Ok, Demet Aydin, Koray Erbüyün, Canan Gürsoy, Fatma Taneli̇, Sema Bi̇lge, Gönül Di̇nç Horasan

Turkish Journal of Medical Sciences

Background/aim: Factors affecting neurological outcome and the usefulness of neuron-specific enolase (NSE), S-100B, glial fibrillary acidic protein (GFAP), and procalcitonin (PCT) in predicting neurological outcomes were assessed in patients who survived at least 24 h after cardiopulmonary resuscitation (CPR). Materials and methods: Thirty successfully resuscitated cardiac arrest patients were included in this prospective clinical study. The initial cardiac arrest rhythm, duration of CPR, return of spontaneous circulation time, administered doses of adrenaline, base excess, blood sugar, and hemodynamic parameters were recorded. Patients with Glasgow Outcome Scale (GOS) scores of 1-3 were defined as Group I and patients with GOS scores …


The Effect Of Cotinine Concentrations In Seminal Plasma And Follicular Fluid On The Pregnancy Outcomes Of Couples Undergoing Assisted Reproductive Techniques, Füsun Terzi̇oğlu, Bensu Karahali̇l, Çi̇ğdem Yücel, Ruki̇ye Türk Jan 2016

The Effect Of Cotinine Concentrations In Seminal Plasma And Follicular Fluid On The Pregnancy Outcomes Of Couples Undergoing Assisted Reproductive Techniques, Füsun Terzi̇oğlu, Bensu Karahali̇l, Çi̇ğdem Yücel, Ruki̇ye Türk

Turkish Journal of Medical Sciences

Background/aim: This study determined the effects of cotinine concentrations in follicular fluid (FF) and seminal plasma (SP) on the pregnancy outcome of couples using assisted reproductive techniques (ARTs). Materials and methods: This study was conducted as a case-control study. A total of 217 couples were included in the study. Among these couples, there were nonsmokers (66 women and 40 men), passive smokers (106 women and 54 men), and active smokers (45 women and 123 men). Demographic and smoking data were collected by questionnaire at the onset of treatment. FF and SP samples were obtained from the couples on the day …


The Effect Of Pneumoperitoneum On Intravascular Fibrinolytic Activity In Rats, Kürşat Di̇kmen, Asi̇ye Uğraş Di̇kmen, Hasan Bostanci, Ahmet Karamercan, Abdullah Münci̇ Yağci, Murat Akin, Bülent Aytaç Jan 2016

The Effect Of Pneumoperitoneum On Intravascular Fibrinolytic Activity In Rats, Kürşat Di̇kmen, Asi̇ye Uğraş Di̇kmen, Hasan Bostanci, Ahmet Karamercan, Abdullah Münci̇ Yağci, Murat Akin, Bülent Aytaç

Turkish Journal of Medical Sciences

Background/aim: Venous stasis during pneumoperitoneum in laparoscopic surgery is closely related to fibrin synthesis and deposition. The etiologic factors underlying fibrinolysis or hypercoagulability are not clearly defined. This study aimed to determine the effects of pneumoperitoneum time and pressure on coagulation cascade and the fibrinolytic pathway. Materials and methods: After the pneumoperitoneum model was established in rats, PAI-1, tPA, TAFI, D-dimer, and fibrinogen activities were evaluated in different time periods under different pressures in groups including 6 rats. Group 1 did not undergo any procedure. Group 2 received 8 mmHg of pressure for 30 min, Group III 8 mmHg for …


Adulthood Behavioral And Neurodevelopmental Effects Of Being Raised Byan Ambivalent Mother In Rats: What Does Not Kill You Makes You Stronger, Refi̇a Aslihan Dönmez, Selçuk Candansayar, Okşan Deri̇nöz, Özlem Gülbahar, Hayrunni̇sa Bolay Jan 2016

Adulthood Behavioral And Neurodevelopmental Effects Of Being Raised Byan Ambivalent Mother In Rats: What Does Not Kill You Makes You Stronger, Refi̇a Aslihan Dönmez, Selçuk Candansayar, Okşan Deri̇nöz, Özlem Gülbahar, Hayrunni̇sa Bolay

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate the effects of early adverse life events and being raised by an ambivalent mother on rats. Materials and methods: The rats were separated into four groups: 1) the control group (n = 12), which was raised under standard care; 2) the early handling (EH) group, which was raised using an EH model (n = 16); 3) the early deprivation (ED) group, which was raised using an ED model (n = 13), and 4) the ambivalent mother (AM) group, which spent 3 h/day with a "fake mother" (n = 17). When they became adults, their …


Effect Of Resveratrol On Resistin And Apelin Gene Expressions In Adipose Tissue Of Diabetic Rats, Sadegh Zarei, Massoud Saidijam, Jamshid Karimi, Reza Yadegarazari, Azam Rezaei Farimani, Solmazsaadat Hosseini-Zijood, Mohammad Taghi Goodarzi Jan 2016

Effect Of Resveratrol On Resistin And Apelin Gene Expressions In Adipose Tissue Of Diabetic Rats, Sadegh Zarei, Massoud Saidijam, Jamshid Karimi, Reza Yadegarazari, Azam Rezaei Farimani, Solmazsaadat Hosseini-Zijood, Mohammad Taghi Goodarzi

Turkish Journal of Medical Sciences

Background/aim: Adipose tissue plays a major role in glucose homeostasis. Dietary antioxidants such as resveratrol (RSV) may offer some protection against the early stage of diabetes mellitus and the development of complications. The present study investigated the effects of RSV on biochemical parameters and resistin and apelin gene expressions in adipose tissue of rats with type 2 diabetes. Materials and methods: Diabetes was induced using a single dose of streptozotocin + nicotinamide. Three groups of diabetic rats were treated with different doses of RSV (1, 5, and 10 mg/kg body weight per day). Oxidative status, serum biochemical parameters, insulin, and …


Boswellia Serrata Gum Resin Aqueous Extract Upregulatesbdnf But Not Creb Expression In Adult Male Rat Hippocampus, Mohammad Khalaj-Kondori, Farzaneh Sadeghi, Mohammad Ali Hosseinpourfeizi, Farzam Shaikhzadeh-Hesari, Aylar Nakhlband, Mohammad Rahmati-Yamchi Jan 2016

Boswellia Serrata Gum Resin Aqueous Extract Upregulatesbdnf But Not Creb Expression In Adult Male Rat Hippocampus, Mohammad Khalaj-Kondori, Farzaneh Sadeghi, Mohammad Ali Hosseinpourfeizi, Farzam Shaikhzadeh-Hesari, Aylar Nakhlband, Mohammad Rahmati-Yamchi

Turkish Journal of Medical Sciences

Background/aim: Boswellia from the family Burseraceae has been proposed for prevention of amnesia; however, the molecular mechanism by which it affects memory is not clear. To reveal the potential molecular mechanism, the effects of boswellia on the expression of two memory related genes, CREB and BDNF, were investigated. Materials and methods: Twenty-one male rats were randomly divided into 3 groups (n = 7): the control group received distilled water and the treatment groups received two doses of aqueous extract of Boswellia serrata gum resin (boswellia) (50 and 100 mg/kg) every day for 4 weeks. The animals were tested by the …


Effects Of Crocin On Experimental Obesity And Type-2 Diabetes, Ömer Hazman, Laçi̇ne Aksoy, Ahmet Büyükben Jan 2016

Effects Of Crocin On Experimental Obesity And Type-2 Diabetes, Ömer Hazman, Laçi̇ne Aksoy, Ahmet Büyükben

Turkish Journal of Medical Sciences

Background/aim: The aim of this study is to scrutinize the effects of crocin on obesity and type-2 diabetes, with an approach that takes oxidative stress and inflammatory parameters into account. Materials and methods: The experimental obesity model was created by utilizing a 10-week-long high-fat diet (HFD). An experimental type-2 diabetes model was created by injecting multiple low-dose streptozocin (STZ) injections into rats that were fed with the HFD. The treatment groups were administered a daily crocin dose of 150 mg/kg for 6 weeks via gavage. Results: Findings of the study demonstrated that crocin could be effective in relieving the symptoms …


Vascular Endothelial Growth Factor And Biphasic Calcium Phosphate In The Endosseous Healing Of Femoral Defects: An Experimental Rat Study, Elçin Bedeloğlu, Selim Ersanlı, Volkan Arısan Jan 2016

Vascular Endothelial Growth Factor And Biphasic Calcium Phosphate In The Endosseous Healing Of Femoral Defects: An Experimental Rat Study, Elçin Bedeloğlu, Selim Ersanlı, Volkan Arısan

Journal of Dental Sciences

Abstract Background/purpose The presence of adequate bone volume is a critical factor in rehabilitative dentistry. Despite the use of many promising alloplasts, success in stimulating bone formation has been limited, mostly due to poor local biological response. Growth factors have been introduced to stimulate angiogenesis and new bone formation. This histologic and histomorphometric study aimed to evaluate the effect of vascular endothelial growth factor (VEGF) and a biphasic alloplastic graft material (BA) on the healing of endosseous defects in rats. Materials and methods Twenty male Wistar rats were used. Two critical-sized bone defects were created in both the right and …


Effect Of Different Extenders On Motility And Some Sperm Kinematics Parameters In Norduz Goat Semen, Koray Teki̇n, Ali̇ Daşkin Jan 2016

Effect Of Different Extenders On Motility And Some Sperm Kinematics Parameters In Norduz Goat Semen, Koray Teki̇n, Ali̇ Daşkin

Turkish Journal of Veterinary & Animal Sciences

Use of computer-assisted sperm analyzers (CASAs) to evaluate sperm fertilizing ability has great importance for the artificial insemination industry. For motility evaluation, different CASA systems and diluents are being used. These assays are poor in predicting sperm fertility, because only the samples with markedly poor quality can be detected. However, there is not a unitary extender worldwide. Therefore, we aimed to evaluate the postthaw kinetic parameters of curvilinear velocity (VCL), straight-line velocity (VSL), and average-path velocity (VAP) with two different extenders (skim milk, SM; Tris, TS). Semen was collected twice a week with an artificial vagina from four adult Norduz …


Pharmacokinetics And Bioavailability Of Three Promising Tilmicosin-Loaded Lipid Nanoparticles In Comparison With Tilmicosin Phosphate Following Oral Administration In Broiler Chickens, Ali Rassouli, Alwan Al-Qushawi, Fatemeh Atyabi, Seyed Mostafa Peighambari, Mehdi Esfandyari-Manesh, Gholam Reza Shams Jan 2016

Pharmacokinetics And Bioavailability Of Three Promising Tilmicosin-Loaded Lipid Nanoparticles In Comparison With Tilmicosin Phosphate Following Oral Administration In Broiler Chickens, Ali Rassouli, Alwan Al-Qushawi, Fatemeh Atyabi, Seyed Mostafa Peighambari, Mehdi Esfandyari-Manesh, Gholam Reza Shams

Turkish Journal of Veterinary & Animal Sciences

Tilmicosin (TLM) is a semisynthetic antimicrobial agent used mainly in poultry and cattle, but it has relatively poor oral bioavailability. This study was conducted to compare the bioavailability (BA) and main pharmacokinetic (PK) parameters of TLM after oral administration of tilmicosin phosphate (TLM-PH) and three newly prepared lipid nanoparticles (LNPs) of TLM including solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), and lipid-core nanocapsules (LNCs). Sixty broiler chickens were divided into eight groups. In four treatment groups (n = 10), each bird was given a single oral dose (20 mg/kg) of a TLM formulation after overnight fasting, and in four …


Hemopoiesis In The Pronephros Of Tench, Tinca Tinca, Linnaeus 1758(Teleostei, Cyprinidae): Cytochemical Identification And Cell Morphology, Andi Alijagic, Damir Suljevic Jan 2016

Hemopoiesis In The Pronephros Of Tench, Tinca Tinca, Linnaeus 1758(Teleostei, Cyprinidae): Cytochemical Identification And Cell Morphology, Andi Alijagic, Damir Suljevic

Turkish Journal of Veterinary & Animal Sciences

Hemopoiesis in the tench (Tinca tinca: Teleostei, Cyprinidae), a cyprinid fish that can be found within the entire territory of Eurasia, from France in the west to the Yenisei River in the east, has not yet been described. The aim of this research was analysis of hemopoiesis lineages in the pronephros of Tinca tinca (sampled from the Jablanicko Reservoir). Identification and cells measurements were done by using a light microscope (Olympus BX41) and an Olympus DP12 camera. Hemopoietic cells of the tench are divided into five different series that include erythropoietic, granulopoietic, lymphopoietic, thrombopoietic, and monopoietic cell series. Erythropoietic series …


Differences In Drone Sperm Morphometry And Activity At The Beginning And End Of The Season, Aldona Gontarz, Dorota Banaszewska, Magdalena Gryzinska, Katarzyna Andraszek Jan 2016

Differences In Drone Sperm Morphometry And Activity At The Beginning And End Of The Season, Aldona Gontarz, Dorota Banaszewska, Magdalena Gryzinska, Katarzyna Andraszek

Turkish Journal of Veterinary & Animal Sciences

The sperm cells of the honey bee, like the sperm of most invertebrates, belong to the modified type of spermatozoa. In our own research, differences have been observed in the activity of sperm cells isolated from drones at the beginning and end of the season. On the basis of these observations, research was undertaken to determine whether the changes in drone activity are associated with morphological changes. The sperm cells collected from drones at the beginning of the mating season are longer than the sperm cells from the end of the season. Moreover, sperm cells from the beginning of the …


Investigation Of The Promoter Polymorphisms Of The Growth Hormone (Gh1), Growth Hormone Receptor (Ghr), Insulin-Like Growth Factor (Igf-I), And Prolactin (Prl) Genes And The Correlation Between Gene Expression And Milk Yields In Holstein Cattle Raised In Central Anatolia, Korhan Arslan, Serpi̇l Taheri̇, Eli̇f Funda Şener, Bi̇lal Akyüz, Aytaç Akçay, Yusuf Özkul, Kaan Muhsi̇n İşcan Jan 2016

Investigation Of The Promoter Polymorphisms Of The Growth Hormone (Gh1), Growth Hormone Receptor (Ghr), Insulin-Like Growth Factor (Igf-I), And Prolactin (Prl) Genes And The Correlation Between Gene Expression And Milk Yields In Holstein Cattle Raised In Central Anatolia, Korhan Arslan, Serpi̇l Taheri̇, Eli̇f Funda Şener, Bi̇lal Akyüz, Aytaç Akçay, Yusuf Özkul, Kaan Muhsi̇n İşcan

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to investigate the promoter polymorphisms of the growth hormone (GH1), growth hormone receptor (GHR), insulin-like growth factor (IGF-I), and prolactin (PRL) genes, and the correlation of the expression levels of these genes with lactation and daily milk yields in Holstein cattle. A total of 154 lactating Holstein cows raised in the Central Anatolia Region of Turkey, with a mean age of 5.4 years and a mean body weight of 571.7 kg, constituted the study material. Each blood sample was examined by real-time PCR for mRNA expression levels and the promoter polymorphisms of the GH1, …


Molecular And Seroprevalence Of Canine Visceral Leishmaniasis In West Anatolia, Turkey, Serkan Bakirci, Hüseyi̇n Bi̇lgi̇n Bi̇lgi̇ç, Onur Köse, Ayça Aksulu, Seli̇n Hacilarlioğlu, Hasan Erdoğan, Tüli̇n Karagenç Jan 2016

Molecular And Seroprevalence Of Canine Visceral Leishmaniasis In West Anatolia, Turkey, Serkan Bakirci, Hüseyi̇n Bi̇lgi̇n Bi̇lgi̇ç, Onur Köse, Ayça Aksulu, Seli̇n Hacilarlioğlu, Hasan Erdoğan, Tüli̇n Karagenç

Turkish Journal of Veterinary & Animal Sciences

Canine leishmaniasis (CanL) is a protozoal disease caused by Leishmania species. Dogs play an important role as a reservoir. The aim of this study is to determine the prevalence of CanL by molecular and serological techniques among stray dogs living in kennels in Aydın, Manisa, and İzmir, located in western Turkey. Blood samples were collected from a total of 191 dogs and analyzed using indirect immunofluorescence antibody test (IFAT) and polymerase chain reaction (PCR). The isolates that tested positive using PCR were further analyzed by real-time PCR for species identification and confirmation. A total of 21 (10.99%) dogs were found …


Ovine Coccidiosis: Prevalence And Associated Risk Factors Inand Around Addis-Zemen, Northwest Ethiopia, Abinet Lakew, Zewdu Seyoum Jan 2016

Ovine Coccidiosis: Prevalence And Associated Risk Factors Inand Around Addis-Zemen, Northwest Ethiopia, Abinet Lakew, Zewdu Seyoum

Turkish Journal of Veterinary & Animal Sciences

This cross-sectional study was conducted in and around Addis-Zemen from November 2014 to April 2015 to determine the prevalence of ovine coccidiosis and to identify associated risk factors. Faecal samples were collected directly from the rectum of 384 randomly selected animals. A centrifugal faecal flotation technique using saturated salt solution was used to detect Eimeria oocysts. Out of 384 samples, only 88 were found to contain Eimeria oocysts. Eimeria infection was recorded in all age and sex groups of the study animals. A strong significant association was observed (P < 0.05) between Eimeria infection and the faecal consistency, production system, hygienic status, age, and body condition of the sampled animals. However, an insignificant (P > 0.05) association was recorded between Eimeria infection and the origins and …


The Determination Of In Vitro Gas Production And Metabolizable Energy Value Of Rice Straw Treated With Exogenous Fibrolytic Enzymes, Zehra Selçuk, Nurcan Çeti̇nkaya, Mustafa Salman, Buğra Genç Jan 2016

The Determination Of In Vitro Gas Production And Metabolizable Energy Value Of Rice Straw Treated With Exogenous Fibrolytic Enzymes, Zehra Selçuk, Nurcan Çeti̇nkaya, Mustafa Salman, Buğra Genç

Turkish Journal of Veterinary & Animal Sciences

This study was conducted to determine the effects of cellulase and xylanase treatments on in vitro 24-h gas production (GP), organic matter digestibility (OMD), and metabolizable energy (ME) values of rice straw (RS). Rice straws were treated with cellulase and xylanase at the levels of 0% (C1), 0.5% (RS+CEL0.5), 1% (RS+CEL1), 1.5% (RS+CEL1.5), and 2% (RS+CEL2) and 0% (C2), 0.5% (RS+XYL0.5), 1% (RS+XYL1), 1.5% (RS+XYL1.5), and 2% (RS+XYL2), respectively. Rice straws treated with each level of cellulase and xylanase were ensiled in 6 glass jars. For each level of cellulase and xylanase treatment, 3 glass jars were incubated at room …


Coaches' Perceptions Of Long-Term Potential Are Biased By Maturational Variation, A Cripps, L Hopper, C Joyce Jan 2016

Coaches' Perceptions Of Long-Term Potential Are Biased By Maturational Variation, A Cripps, L Hopper, C Joyce

Health Sciences Papers and Journal Articles

Talent identification and development programs seek to recognise and promote athletes with long-term potential in a particular sport. Coaches involved in these programs are often required to make inclusions or exclusion decisions based on their perceptions of an athlete’s long-term potential. However, biological maturity can influence physical capabilities of adolescent athletes and may bias coaches’ perceptions of long-term potential. This study explored the relationship between coaches’ perceptions of long-term potential and variations in athlete’s biological maturity. Talented adolescent male Australian footballers from nine (n = 264) different teams were recruited to provide basic anthropometric information for estimates of biological maturity. …


Synthesis, And Prediction Of Molecular Properties And Antimicrobial Activity Of Some Acylhydrazones Derived From $N$-(Arylsulfonyl)Methionine, Esra Tatar, Sevi̇l Şenkardeş, Hasan Erdi̇nç Selli̇tepe, Şükri̇ye Güni̇z Küçükgüzel, Şengül Alpay Karaoğlu, Ari̇f Bozdeveci̇, Erik De Clercq, Christophe Pannecouque, Tai̇bi̇ Ben Hadda, İlkay Küçükgüzel Jan 2016

Synthesis, And Prediction Of Molecular Properties And Antimicrobial Activity Of Some Acylhydrazones Derived From $N$-(Arylsulfonyl)Methionine, Esra Tatar, Sevi̇l Şenkardeş, Hasan Erdi̇nç Selli̇tepe, Şükri̇ye Güni̇z Küçükgüzel, Şengül Alpay Karaoğlu, Ari̇f Bozdeveci̇, Erik De Clercq, Christophe Pannecouque, Tai̇bi̇ Ben Hadda, İlkay Küçükgüzel

Turkish Journal of Chemistry

A series of 38 new acylhydrazones [3-40], derived from (2$S)$-4-(methylsulfanyl)-2-[[(4-methylphenyl)sulfonyl] amino]butanoic acid hydrazide [2], were synthesized and evaluated for their anti-HIV and antimicrobial activity with the further aim to develop acylhydrazones carrying an amino acid side chain. All tested compounds possess stronger activity against gram (+) bacteria. Compound 23 was found active against methicillin-resistant Staphylococcus aureus (MRSA) with a MIC value of 3.9 $\mu $g/mL. The MIC value of compound 30 against Enterococcus faecalis, Listeria monocytogenes, and Bacillus cereus was 8 $\mu $g/mL. A computational study for prediction of ADME and drug-like properties (solubility, drug-likeness, and drug score) as well …


Electrochemical Investigation Of2-[8-Hydroxyquinoline-5-Yl)Azo]Benzo[$C$]Cinnoline On A Platinum Electrode In Dimethysulfoxide, Funda Öztürk, Zehra Yazan, Oznur Olmez, Emi̇ne Kiliç, Esma Kiliç Jan 2016

Electrochemical Investigation Of2-[8-Hydroxyquinoline-5-Yl)Azo]Benzo[$C$]Cinnoline On A Platinum Electrode In Dimethysulfoxide, Funda Öztürk, Zehra Yazan, Oznur Olmez, Emi̇ne Kiliç, Esma Kiliç

Turkish Journal of Chemistry

2-[8-hydroxyquinoline-5-yl)azo]benzo[c]cinnoline was synthesized for the first time and shown to possess electrochromic characteristic, i.e. changing color during the forward and back electrolysis at --1.35 V and 0.00 V, respectively, in DMSO medium. Therefore, the electrochemical investigation of this compound appears to be worthwhile. The electrochemical reduction of 2-[8-hydroxyquinoline-5-yl)azo]benzo[c]cinnoline was investigated by cyclic voltammetry, controlled potential electrolysis, and chronoamperometry techniques in the presence of 0.10 mol L$^{-1}$ tetrabutylammonium tetrafluoroborate in dimethyl sulfoxide at platinum electrode. 2-[8-Hydroxyquinoline-5-yl)azo]benzo[c] cinnoline displays three sharp cathodic peaks and three anodic peaks in the cyclic voltammogram. The diffusion coefficients and the number of electrons transferred were calculated …


Latest Trends, Green Aspects, And Innovations In Liquid-Phase--Based Microextraction Techniques: A Review, Erkan Yilmaz, Mustafa Soylak Jan 2016

Latest Trends, Green Aspects, And Innovations In Liquid-Phase--Based Microextraction Techniques: A Review, Erkan Yilmaz, Mustafa Soylak

Turkish Journal of Chemistry

Liquid-phase microextraction (LPME) methods including single-drop microextraction (SDME), hollow-fiber LPME (HF-LPME), and dispersive liquid-liquid microextraction (DLLME) have in the very short time since their invention grabbed the attention of scientists. Up to now, LPME methods have shown important innovations for the extraction and preconcentration of both inorganic and organic trace analytes from different matrices. These LPME methods offer unique advantages such as high preconcentration factor for target analytes in a single step, low cost, simplicity, excellent preconcentration capability, sample cleanup and integration of steps, and combined use with almost every analytical measurement technique. We describe the milestones and the combined …