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2016

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A Qualitative Analysis Of Clinician Attitudes And Experiences Learning And Implementing Transdiagnostic Evidence-Based Practices For Eating Disorders, Jennifer Marie Oswald Jan 2016

A Qualitative Analysis Of Clinician Attitudes And Experiences Learning And Implementing Transdiagnostic Evidence-Based Practices For Eating Disorders, Jennifer Marie Oswald

Legacy Theses & Dissertations (2009 - 2024)

Clinician experiences with the implementation of new practices are important factors in facilitating the use of new treatment models and evidence-based practices (EBPs). As such, they provide crucial information to behavioral health dissemination and implementation research. Qualitative interviewing allows researchers to learn from clinician experiences with greater depth and nuance. The present study qualitatively analyzed 8 clinicians’ experiences with the implementation of a new transdiagnostic treatment model for eating disorders (ED) at an intensive residential treatment center. Participating clinicians completed a semi-structured interview based on constructs from the Consolidated Framework for Implementation Research (CFIR), an organizing framework with demonstrated utility …

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Bayesian Signal Detection And Source Separation In Simulated Brain Computer Interface Systems, Muhammad Asim Mubeen Jan 2016

Bayesian Signal Detection And Source Separation In Simulated Brain Computer Interface Systems, Muhammad Asim Mubeen

Legacy Theses & Dissertations (2009 - 2024)

The problems of signal detection and source separation are important in many fields of science and engineering. In many cases, a target signal needs to be detected in real time and is contaminated by noise. Sometimes the level of noise is on the order of the signal itself. The real time detection of a target signal is of key importance in problems such as the brain computer interface systems. In brain computer interface systems, the neural activity (electric signals) of the brain is detected using sensors (electrodes) on the surface of the brain or the scalp. This signal is contaminated …

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Beta-Sheet Forming Peptides By Design : Control Of Folding And Applications, Gaius Takor Jan 2016

Beta-Sheet Forming Peptides By Design : Control Of Folding And Applications, Gaius Takor

Legacy Theses & Dissertations (2009 - 2024)

The focus of the present research is the synthesis of polypeptides for the study of protein folding and misfolding and for the development of novel polypeptide-based optical antennas in nanotechnology. It is hypothesized that simple polypeptides can be used as models to mimic in vivo folding of globular proteins. Desired repetitive polypeptides were genetically encoded and expressed in E. coli using conventional methods and characterized using a variety of spectroscopic (including circular dichroism (CD), deep UV resonance Raman (DUVRR), UV-vis and fluorescence) and microscopic (atomic force microscopy (AFM) and transmission electron microscopy (TEM)) techniques. The polypeptides predominantly formed bilayer, fibrillar …

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Low-Level Arsenic Exposure Via Drinking Water And Female Fecundity, Michele L. Susko Jan 2016

Low-Level Arsenic Exposure Via Drinking Water And Female Fecundity, Michele L. Susko

Legacy Theses & Dissertations (2009 - 2024)

Abstract

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Identifying The Limits Of Sexual Liberation As A Feminist Value, Nichole Hungerford Jan 2016

Identifying The Limits Of Sexual Liberation As A Feminist Value, Nichole Hungerford

Legacy Theses & Dissertations (2009 - 2024)

This thesis explores feminist responses to the sexual revolution and the extent to which sexual liberation, from the perspective of heterosexual relations, has served women’s interests as an oppressed social group under patriarchy. In particular, this thesis examines the divide between libertarian and radical feminists’ interpretation of sexual liberation, considering both the radical feminist criticisms of the sexist nature of heterosexual sex and the libertarian feminist view of free sexuality as a revolutionary act that ameliorates the condition of women. This thesis offers a middle ground approach to sexual liberation as a feminist value by suggesting two conditions on heterosexual …

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The Effects Of Economic Factors On The Out-Of-Home Placement For Neglected Children, Mi Jin Choi Jan 2016

The Effects Of Economic Factors On The Out-Of-Home Placement For Neglected Children, Mi Jin Choi

Legacy Theses & Dissertations (2009 - 2024)

U.S. child welfare services provides children who cannot be cared for by their families with out-of-home (OOH) care, which is temporary residential care outside of a child’s original home. Economic factors are critical in making consistent OOH placement decisions due to their relationship with child development and safety.

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Air-Sea Carbon Dioxide Exchange In The Southern Ocean And Antarctic Sea Ice Zone, Brian Butterworth Jan 2016

Air-Sea Carbon Dioxide Exchange In The Southern Ocean And Antarctic Sea Ice Zone, Brian Butterworth

Legacy Theses & Dissertations (2009 - 2024)

The Southern Ocean is an important part of the global carbon cycle, responsible for roughly half of the carbon dioxide (CO2) absorbed by the global ocean. The air-sea CO2 flux (Fc) can be expressed as the product of the water-air CO2 partial pressure difference (ΔpCO2) and the gas transfer velocity (k), an exchange coefficient which represents the efficiency of gas exchange. Generally, Fc is negative (a sink) throughout the Southern Ocean and Antarctic sea ice zone (SIZ), but uncertainty in k has made it difficult to develop an accurate regional carbon budget. Constraining the functional dependence of k on wind …

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Teacher Educators' Use Of Research-Based Literature In Their Pedagogical Practice, Leigh Yannuzzi Jan 2016

Teacher Educators' Use Of Research-Based Literature In Their Pedagogical Practice, Leigh Yannuzzi

Legacy Theses & Dissertations (2009 - 2024)

Teacher education programs are situated at a critical point of intersection between the worlds of P-12 education, higher education, and educational policy. However, description and analysis of teacher educator programs, and specifically teacher educator practice, has yet to consider the role research literature plays in faculty work with pre-service teachers. This study provides an exploratory examination of knowledge dissemination in teacher education and analyzes mechanisms for, challenges to, and influences on the use of research literature with pre-service teachers. It contributes to scholarship by providing new knowledge about how teacher education faculty use the dissemination mechanism of course syllabi to …

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Exploring The Association Between Perceived Safety Of Household Children In The Neigborhood And Levels Of Depressive Symptoms Among Spanish Speaking Latina Adults Living In A High Crime, Low Income Neigbhorhood, Randall Stetson Jan 2016

Exploring The Association Between Perceived Safety Of Household Children In The Neigborhood And Levels Of Depressive Symptoms Among Spanish Speaking Latina Adults Living In A High Crime, Low Income Neigbhorhood, Randall Stetson

Legacy Theses & Dissertations (2009 - 2024)

Previous research has confirmed that neighborhood level social factors (e.g. crime, safety) present chronic stressors that increase risk for depression in residents of economically disadvantaged neighborhoods. U.S. Latinos experience higher levels of poverty and thus are more likely to live in poor neighborhoods. In this study it was hypothesized that adult Latina women who reported (1) higher levels of worry regarding the general safety of their household children in the neighborhood, (2) higher levels of worry regarding influence of bad friends on their household children, and (3) higher levels of worry regarding their household children being exposed to drugs and …

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Mutational Studies Of The Receptor For Advanced Glycation End Products (Rage) Inhibition, Sarah Corte Jan 2016

Mutational Studies Of The Receptor For Advanced Glycation End Products (Rage) Inhibition, Sarah Corte

Legacy Theses & Dissertations (2009 - 2024)

Abstract

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Investigation Of Enzymatically Synthesized Glycogen As A Novel Nanodendrimer For Therapeutic Delivery, Sarah Ann Engelberth Jan 2016

Investigation Of Enzymatically Synthesized Glycogen As A Novel Nanodendrimer For Therapeutic Delivery, Sarah Ann Engelberth

Legacy Theses & Dissertations (2009 - 2024)

The field of medicinal chemistry is ever expanding, designing and discovering new therapeutic strategies. Oftentimes, it is challenging for these therapeutics to undergo clinical translation due to ineffective administration or unwanted toxicity in vivo. As such, drug delivery vehicles are designed to overcome these hurdles, allowing for delivery to the site of action by improving biodistribution, protecting therapeutic cargo, and decreasing toxicity. The work presented here aims to investigate a naturally-derived carbohydrate nanodendrimer, enzymatically synthesized glycogen (ESG) for drug delivery. This nontoxic, highly-branched, glucose-based structure has interior void volumes to allow for cargo encapsulation as well as a large density …

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Factors Associated With Cognitive Development Of Primary School Children In Eastern Indonesia, Nisa Felicia Jan 2016

Factors Associated With Cognitive Development Of Primary School Children In Eastern Indonesia, Nisa Felicia

Legacy Theses & Dissertations (2009 - 2024)

Reasoning, pattern recognition, and problem solving are key cognitive skills developed during

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"Porque Tienen Mucho Derecho" : Parteras, Biomedical Training And The Vernacularization Of Human Rights In Chiapas, Mounia El Kotni Jan 2016

"Porque Tienen Mucho Derecho" : Parteras, Biomedical Training And The Vernacularization Of Human Rights In Chiapas, Mounia El Kotni

Legacy Theses & Dissertations (2009 - 2024)

This doctoral research stems from thirteen months of ethnographic fieldwork in the Mexican State of Chiapas. Chiapas is one of the regions with the highest maternal mortality rates in the country. To comply with international development goals to lower maternal mortality rates, indigenous midwives are trained in detecting risk factors in pregnancy and birth, while women are encouraged to give birth in hospitals. This dissertation sheds light on the impact of such policies on poor women's access to reproductive health care and Mayan midwives' practices. Over the course of my research, I utilized the methodology of participant-observation and conducted in-depth …

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The Chemistry Of New Garlic-Derived Organosulfur Compounds And The Molecular Basis Of Olfaction, Berenice Dethier Jan 2016

The Chemistry Of New Garlic-Derived Organosulfur Compounds And The Molecular Basis Of Olfaction, Berenice Dethier

Legacy Theses & Dissertations (2009 - 2024)

Garlic is a very popular condiment that has been used around the world for centuries. It is also a source of a remarkably extensive range of organosulfur compounds, whose chemistry is the focus of this thesis. The central reaction in formation of these compounds is the enzymatic cleavage of alk(en)yl cysteine sulfoxides by alliinases, which leads to sulfenic acids. The latter can then undergo condensation and rearrangement into various organosulfur compounds. Three aspects of the chemistry of garlic have been investigated in this thesis.

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Capacity In Grassroots Nonprofit Organizations : Perspectives From Emergency Food Providers, Bethany Slater Jan 2016

Capacity In Grassroots Nonprofit Organizations : Perspectives From Emergency Food Providers, Bethany Slater

Legacy Theses & Dissertations (2009 - 2024)

Scholars generally agree that organizational capacity influences a nonprofit’s sustainability and overall effectiveness. Identified challenges include defining capacity, operationalizing it and understanding how capacity affects effectiveness. This research project seeks to explore these challenges and examine the construct of capacity from the perspectives of 195 emergency food program practitioners across eleven counties in upstate New York. The qualitative study aims to understand “what” capacity is; the quantitative study aims to understand “how” capacity is operationalized and the mixed method study examines the “why this matters”, through asking how capacity influences effectiveness.

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Study Of Protein-Protein Interaction By Using In-Cell Nmr In Human Cells, Asma Salem M Aldousary Jan 2016

Study Of Protein-Protein Interaction By Using In-Cell Nmr In Human Cells, Asma Salem M Aldousary

Legacy Theses & Dissertations (2009 - 2024)

We developed a new technology to study protein-protein interaction in mammalian cells. This technology is based high resolution of Nucleic Magnetic Resonance (NMR) spectroscopy. Using this technology we studied interaction between the receptor for advanced glycation endproducts (RAGE). RAGE- is a multiligand receptor of immunoglobulin receptor family that is activated by a multitude of ligands. Activation of RAGE results in signal transduction that leads to the inflammatory response implicated in the complications of Diabetes. RAGE is an emergent drug target that has been explored for the variety of pathologist including cancers, neurological disorders, inflammatory disease, and diabetes. and Intracellular effector …

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A Survey Of The Current Drug Screening Techniques To Obtain Rational Design And Study Drug-Target Interactions, Stephen Dansereau Jan 2016

A Survey Of The Current Drug Screening Techniques To Obtain Rational Design And Study Drug-Target Interactions, Stephen Dansereau

Legacy Theses & Dissertations (2009 - 2024)

Different techniques have been developed over the years for the purpose of studying proteins and understanding their functions. Early techniques typically employed bioluminescence or fluorescence such such as the firefly protein luciferase and the jellyfish green fluorescent protein (GFP), respectively, to localize proteins within the cell. X-ray crystallography has also provided valuable structural details of many different proteins in vitro. Yet, nuclear magnetic resonance (NMR) spectroscopy offers the most realistic insight into proteins' physiologic structures and how proteins function in their native, cellular environments.

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Antibody-Mediated Immunity To Vibrio Cholerae At Epithelial Surfaces, Kara Jeanette Levinson Jan 2016

Antibody-Mediated Immunity To Vibrio Cholerae At Epithelial Surfaces, Kara Jeanette Levinson

Legacy Theses & Dissertations (2009 - 2024)

Vibrio cholerae, the causative agent of the severe diarrheal disease cholera, has an estimated worldwide disease burden in the millions and remains a significant public health threat. Immunity to V. cholerae is primarily antibody-mediated and though V. cholerae colonization evokes a mucosal immune response, it is the secretory IgA (SIgA) antibodies produced against bacterial surface antigens, specifically lipopolysaccharide (LPS) that confer protective immunity. SIgA antibodies are thought to function by inhibiting colonization by cross-linking and agglutination of pathogens, thereby limiting access to the epithelium, a process known as immune exclusion. Recent studies in other enteric pathogens have demonstrated that SIgA …

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Academic Performance In College Online Courses : The Role Of Self-Regulated Learning, Motivation And Academic Self-Efficacy, Catherine L. Basila Jan 2016

Academic Performance In College Online Courses : The Role Of Self-Regulated Learning, Motivation And Academic Self-Efficacy, Catherine L. Basila

Legacy Theses & Dissertations (2009 - 2024)

Abstract

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Parental Aspirations Among Young Gay Men, Daniel Farr Jan 2016

Parental Aspirations Among Young Gay Men, Daniel Farr

Legacy Theses & Dissertations (2009 - 2024)

Today’s young gay men are experiencing life choice options in manners greater than any prior generation of gay men, particularly when considering family building. These men are coming out at earlier ages and facing a socio-political world of increased legal rights and opportunities, among which is the opportunity to parent outside of a heterosexual past. Informed by interviews with 51 gay men, aged 18-35, this research explores the personal views of today’s young gay men about parenting. While past research has primarily focused upon the views of gay men who were already parenting, thus recalling past aspirations, this project focuses …

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Extracellular And Intracellular Neutralization Of Ricin Toxin By Engineered Bispecific Antibodies, Cristina Herrera Jan 2016

Extracellular And Intracellular Neutralization Of Ricin Toxin By Engineered Bispecific Antibodies, Cristina Herrera

Legacy Theses & Dissertations (2009 - 2024)

Engineering anti-toxin antibodies (Ab) is of public health interest for biodefense counter measurements. Ricin toxin is one example of a major biothreat agent that has currently no antidote. Ricin is a glycoprotein from the castor bean plant, Ricinus communis, and belongs to the medically important A-B toxin family that also includes Shiga, anthrax and cholera toxins. Ricin’s enzymatic subunit (RTA) is an RNA N-glycosidase that inhibits protein synthesis by irreversibly depurinating the 28S rRNA of the eukaryotic 60S ribosomal subunit. RTB is a galactose-/N-acetylgalactosamine-specific lectin that has two important functions. First, RTB promotes binding and endocytosis of ricin into mammalian …

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Asymmetry Between Behavioral And Physiological Responses To Stress In Children And The Role Of Depressive Symptoms, Stephanie Emhoff Jan 2016

Asymmetry Between Behavioral And Physiological Responses To Stress In Children And The Role Of Depressive Symptoms, Stephanie Emhoff

Legacy Theses & Dissertations (2009 - 2024)

Research indicates that asymmetry between behavioral and physiological indicators of stress is associated with impairment in physical and psychological health, which may be particularly problematic for child development. The present study examines the impact of depressive symptoms on the relation between behavioral and physiological responses to stress in a sample of 49 youth (ages 9-12). During exposure to an in-lab psychosocial stressor, two laboratory personnel coded participant stress behaviors. These behaviors were later categorized into factors through an exploratory factor analysis. To assess for reactivity in physiological stress response systems, saliva samples were collected at baseline and following the stressor …

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The Use Of Ion Mobility Spectrometry-Mass Spectrometry For The Structural Elucidation Of Progressively Larger Nucleic Acids, Jennifer Lynn Lippens Jan 2016

The Use Of Ion Mobility Spectrometry-Mass Spectrometry For The Structural Elucidation Of Progressively Larger Nucleic Acids, Jennifer Lynn Lippens

Legacy Theses & Dissertations (2009 - 2024)

The biomedical community and pharmaceutical industry have come to rely in ever

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The Enlightenment And The Origins Of Racism, Peter Andrew Schrom Jan 2016

The Enlightenment And The Origins Of Racism, Peter Andrew Schrom

Legacy Theses & Dissertations (2009 - 2024)

The Enlightenment has been thought of as the Age of Reason: the birth of the individual, the rise of print culture, the beginning of the middle class, and an exponential growth in the sciences. The Enlightenment shaped the world into the form that it is today, but it also marks the start of colonization and the slave trade. The following thesis seeks to demonstrate the importance of the Enlightenment to both colonization and the slave trade; that without it neither of these practices would have had the reach that they achieved over time. Using the works of Adam Smith, Jean-Jacques …

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Investigation Into The Function Of Endothelial Cells And Their Signaling In Early Salivary Gland Development, Hae Ryong Kwon Jan 2016

Investigation Into The Function Of Endothelial Cells And Their Signaling In Early Salivary Gland Development, Hae Ryong Kwon

Legacy Theses & Dissertations (2009 - 2024)

Functional vasculature regulates organ formation and regeneration. Perfusion-independent and nutrition-independent endothelial regulation of epithelial patterning is of considerable interest for application in restoring parenchymal function. During murine submandibular salivary gland development, the vasculature co-develops with the epithelium; however, it is still unknown if the vasculature has instructive effects on the epithelium. A systems biological study revealed that endothelial genes are enriched in epithelial clefts, suggesting a potential involvement of endothelial cells in early morphogenesis. Using immunodepletion of the endothelial cells from the mesenchyme of reconstituted glands, a requirement for endothelial cells in epithelial patterning was demonstrated. Specifically, lobule formation was …

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Soil Properties Affect Establishment Of Invasive Species, Celastrus Orbiculatus, In A Lower Hudson River Riparian Ecosystem, Shabana Hoosein Hoosein Jan 2016

Soil Properties Affect Establishment Of Invasive Species, Celastrus Orbiculatus, In A Lower Hudson River Riparian Ecosystem, Shabana Hoosein Hoosein

Legacy Theses & Dissertations (2009 - 2024)

The Hudson River Estuary has been colonized by numerous terrestrial invasive plant species, due in part to its history of anthropogenic and natural disturbance riparian dynamics. This study investigates the spatial patterns of a widespread invasion by Oriental (or Asiatic) bittersweet (Celastrus orbiculatus Thunb.) in Schodack Island State Park, Rensselaer and Columbia Counties. The Park is home to rare species and communities, several of which are threatened by the encroachment of bittersweet. Bittersweet populations were mapped and surveyed on a fixed grid throughout the island, to determine distribution patterns. Stem densities were approximately 50% higher in sites with dredged material …

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Maternal Surgery Or Anesthesia Use During Pregnancy And The Risk Of Adverse Birth Outcomes In The National Birth Defects Prevention Study, 1997-2009, Youjung Byun Jan 2016

Maternal Surgery Or Anesthesia Use During Pregnancy And The Risk Of Adverse Birth Outcomes In The National Birth Defects Prevention Study, 1997-2009, Youjung Byun

Legacy Theses & Dissertations (2009 - 2024)

Background: 50,000 to 75,000 pregnant women are estimated to undergo surgery during pregnancy. This number comprises of 1.5 to 2 percent of the total confirmed pregnancies. Considering most pregnancies are unintended (49%), the number of women undergoing surgery unaware of the pregnancy is expected to be higher than the historical estimate. This study objective is to identify the characteristics of mothers who undergo surgery and assess the association between surgery or anesthesia exposure and the risk of adverse birth outcomes.

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A Phylogenetic Investigation Of The Spittlebug Superfamily Cercopoidea (Insecta: Hemiptera: Auchenorrhyncha) With Emphasis On The Family Machaerotidae, Adam Jorgensen Bell Jan 2016

A Phylogenetic Investigation Of The Spittlebug Superfamily Cercopoidea (Insecta: Hemiptera: Auchenorrhyncha) With Emphasis On The Family Machaerotidae, Adam Jorgensen Bell

Legacy Theses & Dissertations (2009 - 2024)

The superfamily Cercopoidea (Insecta: Hemiptera: Auchenorrhyncha) represents a relatively small insect lineage with just over 2600 species in five described families. Known as spittlebugs, these xylem feeding insects have the unique habit of their nymphs building a frothy matrix of partially digested, excreted plant sap and air bubbles in which they seclude themselves. Despite the size of the superfamily, the phylogenetic relationships among the described families and even the total number of families are still being debated.

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Fine Particulate Air Pollution In Saudi Arabia : Implications For Cardiopulmonary Morbidity, Shedrack Rujooga Nayebare Jan 2016

Fine Particulate Air Pollution In Saudi Arabia : Implications For Cardiopulmonary Morbidity, Shedrack Rujooga Nayebare

Legacy Theses & Dissertations (2009 - 2024)

Fine particulate (PM2.5) air pollution is a major issue in Saudi Arabia. Though the health effects of exposure to PM2.5 have been extensively studied in developed countries of Europe and North America, this research is yet to be done in developing countries of Africa, some parts of Asia and the Middle East including Saudi Arabia. This is the first comprehensive assessment of PM2.5 air pollution in Saudi Arabia describing the major emission sources as well as assessing the association of daily exposures to PM2.5 and its chemical constituents with cardiopulmonary morbidity.

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Postmodern Picturebooks, Gender, And Reading Difficulties : A Phenomenological Exploration Of One Boy's Experiences, Diane Marie Hamilton Jan 2016

Postmodern Picturebooks, Gender, And Reading Difficulties : A Phenomenological Exploration Of One Boy's Experiences, Diane Marie Hamilton

Legacy Theses & Dissertations (2009 - 2024)

Abstract

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