Digital Commons Network^™

Towards An Ecosystem-Based Approach Of Guam's Coral Reefs: The Human Dimension, Mariska Weijerman, Cynthia Grace-Mccaskey, Shanna L. Grafeld, Dawn M. Kotowicz, Kirsten L.L. Oleson, Ingrid E. Van Putten

United States Department of Commerce: Staff Publications

Management of tropical reef ecosystems under pressure from terrestrial and extractive marine activities is not straightforward, especially when the interests of extractive and non-extractive marine resource sectors compete. Before implementing management actions, potential outcomes of alternative management strategies can be evaluated in order to avoid adverse or unintended consequences. In tropical reef ecosystems the continued existence of the cultural and recreational fishing activities and the economically important dive-based tourism and recreation industry rest on sustainably managed marine resources. Through a case study of Guam, an ecosystem model was linked with human behavior models for participation in fishing and diving to …

Characteristics Of Flash Initiations In A Supercell Cluster With Tornadoes, Dong Zheng, Donald R. Macgorman

United States Department of Commerce: Staff Publications

Flash initiations within a supercell cluster during 10–11 May 2010 in Oklahoma were investigated based on observations from the Oklahoma Lightning Mapping Array and the Norman, Oklahoma, polarimetric radar (KOUN). The flash initiations at positions dominated by graupel, dry snow, small hail and crystals accounted for 44.3%, 44.1%, 8.0% and 3.0% of the total flashes, respectively. During the tornadic stage of the southern supercell in the cluster, flash initiations associated with graupel occupied the main body, the right flank and the forward flank of the supercell, while those associated with dry snow dominated the outskirts of the adjacent forward anvil, …

Alpha-Lipoic Acid Supplementation Protects Enzymes From Damage By Nitrosative And Oxidative Stress, Sylvia Hiller, Robert Dekroon, Eric D. Hamlett, Longquan Xu, Cristina Osorio, Jennifer Robinette, Witold Winnik, Stephen Simington, Nobuyo Maeda, Oscar Alzate, Xianwen Yi

United States Environmental Protection Agency: Publications

Background: S-nitrosylation of mitochondrial enzymes involved in energy transfer under nitrosative stress may result in ATP deficiency. We investigated whether α-lipoic acid, a powerful antioxidant, could alleviate nitrosative stress by regulating S-nitrosylation,which could result in retaining themitochondrial enzyme activity.

Methods: In this study, we have identified the S-nitrosylated forms of subunit 1 of dihydrolipoyllysine succinyltransferase (complex III), and subunit 2 of the α-ketoglutarate dehydrogenase complex by implementing a fluorescence-based differential quantitative proteomics method.

Results: We found that the activities of these two mitochondrial enzymes were partially but reversibly inhibited by S-nitrosylation in cultured endothelial cells, and that their activities …

Seasonality Of Coliform Bacteria Detection Rates In New Jersey Domestic Wells, Thomas B. Atherholt, Nicholas A. Procopio, Sandra M. Goodrow

United States Environmental Protection Agency: Publications

It is important that indicators of fecal pollution are reliable. Coliform bacteria are a commonly used indicator of fecal pollution. As other investigators have reported elsewhere, we observed a seasonal pattern of coliform bacteria detections in domestic wells in New Jersey. Examination of a statewide database of 10 years of water quality data from 93,447 samples, from 78,207 wells, generated during real estate transactions, revealed that coliform bacteria were detected in a higher proportion of wells during warm weather months. Further examination of the seasonal pattern of other data, including well water pH, precipitation, ground and surface water temperatures, surface …

Temporal Trends In The Spatial Distribution Of Impervious Cover Relative To Stream Location, J. Wickham, A. Neale, M. Mehaffey, T. Jarnagin, D. Norton

United States Environmental Protection Agency: Publications

Use of impervious cover is transitioning from an indicator of surface water condition to one that also guides and informs watershed planning and management, including Clean Water Act (33 U.S.C. §1251 et seq.) reporting. Whether it is for understanding surface water condition or planning and management, impervious cover is most commonly expressed as summary measurement (e.g., percentage watershed in impervious cover). We use the National Land Cover Database to estimate impervious cover in the vicinity of surface waters for three time periods (2001, 2006, 2011). We also compare impervious cover in the vicinity of surface waters to watershed summary estimates …

Cyanotoxins In Inland Lakes Of The United States: Occurrence And Potential Recreational Health Risks In The Epa National Lakes Assessment 2007, Keith A. Loftin, Jennifer L. Graham, Elizabeth D. Hillborn, Sarah C. Lehmann, Michael T. Meyer, Julie E. Dietze, Christopher B. Griffith

United States Environmental Protection Agency: Publications

A large nation-wide survey of cyanotoxins (1161 lakes) in the United States (U.S.) was conducted during the EPA National Lakes Assessment 2007. Cyanotoxin data were compared with cyanobacteria abundance- and chlorophyll-based World Health Organization (WHO) thresholds and mouse toxicity data to evaluate potential recreational risks. Cylindrospermopsins, microcystins, and saxitoxins were detected (ELISA) in 4.0, 32, and 7.7% of samples with mean concentrations of 0.56, 3.0, and 0.061 mg/L, respectively (detections only). Co-occurrence of the three cyanotoxin classes was rare (0.32%) when at least one toxin was detected. Cyanobacteria were present and dominant in 98 and 76% of samples, respectively. Potential …

Carbon Storage In Us Wetlands, A. M. Nahlik, M. S. Fennessy

United States Environmental Protection Agency: Publications

Wetland soils contain some of the highest stores of soil carbon in the biosphere. However, there is little understanding of the quantity and distribution of carbon stored in our remaining wetlands or of the potential effects of human disturbance on these stocks. Here we use field data from the 2011 National Wetland Condition Assessment to provide unbiased estimates of soil carbon stocks for wetlands at regional and national scales. We find that wetlands in the conterminous United States store a total of 11.52 PgC, much of which is within soils deeper than 30 cm. Freshwater inland wetlands, in part due …

The Tenth Annual Amygdala, Stress, And Ptsd Conference: “The Amygdala: Dysfunction, Hyperfunction, And Connectivity”, Eric M. Prager, Gary H. Wynn, Robert J. Ursano

Uniformed Services University of the Health Sciences

The Amygdala, Stress, and Posttraumatic Stress Disorder (PTSD) Conference, often referred to simply as The Amygdala Conference, is a continuing education conference held each April at the Uniformed Services University (USU) and sponsored by The Center for the Study of Traumatic Stress in collaboration with the USU Department of Psychiatry, USU Neuroscience Program, USU Department of Family Medicine, and The Walter Reed National Military Medical Center Department of Psychiatry. Free and open to the public, this conference brings together nationally and internationally recognized scientists and clinicians to help support the translation of high-quality science into excellent clinical care.

Tgf-Β Signaling In Cancer, Viqar Syed

Uniformed Services University of the Health Sciences

The transforming growth factor-β (TGF- β) is a family of structurally related proteins that comprises of TGF- β, activins/inhibins, and bone morphogenic proteins (BMPs). Members of the TGF- β family control numerous cellular functions including proliferation, apoptosis, differentiation, epithelial-mesenchymal transition (EMT), and migration. The first identified member, TGF- β is implicated in several human diseases, such as vascular diseases, autoimmune disorders, and carcinogenesis. Activation of the TGF- β receptor by its ligands induces the phosphorylation of serine/threonine residues and triggers phosphorylation of the intracellular effectors, SMADs. Upon activation, SMAD proteins translocate to the nucleus and induce transcription of their target …

Prenatal Carbon Monoxide Impairs Migration Of Interneurons Into The Cerebral Cortex, John F. Trentini, J. Timothy O’Neill, Sylvie Poluch, Sharon L. Juliano

Uniformed Services University of the Health Sciences

Prenatal exposure to carbon monoxide (CO) disrupts brain development, however little is known about effects on neocortical maturation. We exposed pregnant mice to CO from embryonic day 7 (E7) until birth. To study the effect of CO on neuronal migration into the neocortex we injected BrdU during corticogenesis and observed misplaced BrdU+ cells. The majority of cells not in their proper layer colocalized with GAD65/67, suggesting impairment of interneuron migration; interneuron subtypes were also affected. We subsequently followed interneuron migration from E15 organotypic cultures of mouse neocortex exposed to CO;[6TD$DIF] the leading process length of migrating neurons diminished. To examine …

A Urinary Metabolic Signature For Multiple Sclerosis And Neuromyelitis Optica, Teklab Gebregiworgis, Helle H. Nielsen, Chandirasegara Massilamany, Arunakumar Gangaplara, Jay Reddy, Zsolt Illes, Robert Powers

Jay Reddy Publications

Urine is a metabolite-rich biofluid that reflects the body’s effort to maintain chemical and osmotic homeostasis. Clinical diagnosis routinely relies on urine samples because the collection process is easy and noninvasive. Despite these advantages, urine is an under-investigated source of biomarkers for multiple sclerosis (MS). Nuclear magnetic resonance spectroscopy (NMR) has become a common approach for analyzing urinary metabolites for disease diagnosis and biomarker discovery. For illustration of the potential of urinary metabolites for diagnosing and treating MS patients, and for differentiating between MS and other illnesses, 38 urine samples were collected from healthy controls, MS patients, and neuromyelitis optica-spectrum …

In-Air Hearing Of A Diving Duck: A Comparison Of Psychoacoustic And Auditory Brainstem Response Thresholds, Sara E. Crowell, Alicia M. Wells-Berlin, Ronald E. Therrien, Sally E. Yannuzzi, Catherine E. Carr

United States Geological Survey: Staff Publications

Auditory sensitivity was measured in a species of diving duck that is not often kept in captivity, the lesser scaup. Behavioral (psychoacoustics) and electrophysiological [the auditory brainstem response (ABR)] methods were used to measure in-air auditory sensitivity, and the resulting audiograms were compared. Both approaches yielded audiograms with similar U-shapes and regions of greatest sensitivity (2000-3000 Hz). However, ABR thresholds were higher than psychoacoustic thresholds at all frequencies. This difference was least at the highest frequency tested using both methods (5700 Hz) and greatest at 1000 Hz, where the ABR threshold was 26.8 dB higher than the behavioral measure of …

Migratory Bird Program At The U.S. Geological Survey Patuxent Wildlife Research Center/U.S. Fish And Wildlife Service Patuxent Research Refuge: Transformations In Management And Research, R. Michael Erwin, Robert Blohm

United States Geological Survey: Publications

The Patuxent Wildlife Research Center (Patuxent), first known as the Patuxent Research Refuge, has a long and rich history of participation in the Department of Interior’s (DOI) cooperative efforts to protect and conserve migratory birds in North America. This chapter describes many of the events and the people involved that constitute this important timeline for international conservation of a shared wildlife resource. The Patuxent Research Refuge, renowned worldwide, is part of the National Wildlife Refuge System of the U.S. Fish and Wildlife Service (USFWS) that has, at different times and under a variety of organizational iterations, provided the physical location …

Polaris: A 30-Meter Probabilistic Soil Series Map Of The Contiguous United States, Nathaniel W. Chaney, Eric F. Wood, Alexander B. Mcbratney, Jonathan W. Hempel, Travis W. Nauman, Colby W. Brungard, Nathan P. Odgers

United States Geological Survey: Staff Publications

A newcomplete map of soil series probabilities has been produced for the contiguous United States at a 30mspatial resolution. This innovative database, named POLARIS, is constructed using available high-resolution geospatial environmental data and a state-of-the-art machine learning algorithm (DSMART-HPC) to remap the Soil Survey Geographic (SSURGO) database. This 9 billion grid cell database is possible using available high performance computing resources. POLARIS provides a spatially continuous, internally consistent, quantitative prediction of soil series. It offers potential solutions to the primary weaknesses in SSURGO: 1) unmapped areas are gap-filled using survey data from the surrounding regions, 2) the artificial discontinuities at …

Paying The Pipers: Mitigating The Impact Of Anticoagulant Rodenticides On Predators And Scavengers, John E. Elliott, Barnett A. Rattner, Richard F. Shore, Nico W. Van Den Brink

United States Geological Survey: Staff Publications

Anticoagulant rodenticides, mainly second-generation forms, or SGARs, dominate the global market for rodent control. Introduced in the 1970s to counter genetic resistance in rodent populations to first-generation compounds such as warfarin, SGARs are extremely toxic and highly effective killers. However, their tendency to persist and accumulate in the body has led to the widespread contamination of terrestrial predators and scavengers. Commercial chemicals that are classified by regulators as persistent, bio-accumulative, and toxic (PBT) chemicals and that are widely used with potential environmental release, such as dichloro-diphenyl-trichloroethane (DDT) or polychlorinated biphenyls (PCBs), have been removed from commerce. However, despite consistently failing …

Chesapeake Bay Fish–Osprey (Pandion Haliaetus) Food Chain: Evaluation Of Contaminant Exposure And Genetic Damage, Rebecca S. Lazarus, Barnett A. Rattner, Peter C. Mcgowan, Robert C. Hale, Natalie K. Karouna-Renier, Richard A. Erickson, Mary Ann Ottinger

United States Geological Survey: Staff Publications

From 2011 to 2013, a large-scale ecotoxicological study was conducted in several Chesapeake Bay (USA) tributaries (Susquehanna River and flats, the Back, Baltimore Harbor/Patapsco Rivers, Anacostia/ middle Potomac, Elizabeth and James Rivers) and Poplar Island as a mid-Bay reference site. Osprey (Pandion haliaetus) diet and the transfer of contaminants from fish to osprey eggs were evaluated. The most bioaccumulative compounds (biomagnification factor>5) included p,p’-dichlorodiphenyldichloroethylene (DDE), total polychlorinated biphenyls (PCBs), total polybrominated diphenyl ethers (PBDEs), and bromodiphenyl ether (BDE) congeners 47, 99, 100, and 154. This analysis suggested that alternative brominated flame retardants and other compounds (methoxytriclosan) are not appreciably …

Immunoglobulin Detection Inwild Birds: Effectiveness Of Three Secondary Anti-Avian Igy Antibodies In Direct Elisas In 41 Avian Species, Carol A. Fassbinder-Orth, Travis E. Wilcoxen, Tiffany Tran, Raoul K. Boughton, Jeanne M. Fair, Erik K. Hofmeister, Jennifer L. Grindstaff, Jen C. Owen

United States Geological Survey: Staff Publications

1.Immunological reagents for wild, non-model species are limited or often non-existent for many species.

2. In this study, we compare the reactivity of a newanti-passerine IgY secondary antibody with existing secondary antibodies developed for use with birds. Samples from 41 species from the following six avian orders were analysed: Anseriformes (1 family, 1 species), Columbiformes (1 family, 2 species), Galliformes (1 family, 1 species), Passeriformes (16 families, 34 species), Piciformes (1 family, 2 species) and Suliformes (1 family, 1 species). Direct ELISAs were performed to detect total IgY using goat anti-passerine IgY, goat anti-chicken IgY or goat anti-bird IgY secondary …

Endangered Species Research In The Caribbean, James W. Wiley

United States Geological Survey: Staff Publications

Although indigenous Amerindian populations adversely affected the biota of their island environments, it was not until the arrival of Europeans that populations of many plant and animal species in the Caribbean Islands declined dramatically (Snyder and others, 1987). Island species are particularly vulnerable to changes in the environment, which, in the extreme, can lead to their extinction. The small populations of many species that occupy islands have limited gene pools and typically show extremes of specialization, characteristics that place those species at high risk for decline and extinction with rapid environmental change. The most important factor in the decline of …

The Bird Banding Laboratory: Support For And Collaboration With Research At Patuxent, John Tautin

United States Geological Survey: Staff Publications

Located at Patuxent Research Refuge (PRR) and functionally part of the Patuxent Wildlife Research Center (Patuxent), Laurel, MD, the Bird Banding Laboratory (BBL) is the service and administrative center for bird banding in the United States. Over the years, the BBL has been associated with both the PRR and Patuxent, which collectively are commonly referred to by the public (and in this chapter) as “Patuxent.” The BBL issues permits and bands; supplies banding software, instructional materials, and technical advice; coordinates the use of auxiliary markers such as neck collars and radio transmitters; serves as the repository for banding records and …

Endangered Species Research In Hawaii: The Early Years (1965–87), Michael J. Scott, Cameron B. Kepler

United States Geological Survey: Staff Publications

Hawaii is an ecologically isolated archipelago 2,500 miles from the nearest continent. Its isolation resulted in a taxonomically unbalanced flora and fauna with remarkable examples of adaptive radiation among those groups of organisms that won the dispersal sweepstakes. It was one of the last oceanic island groups to be populated by humans, about 900 A.D. by Polynesian travelers and in 1778 by Europeans. Relatively recent colonization by humans did not save it, however, from the biodiversity losses suffered by other isolated archipelagos—it only delayed them (Scott and others, 1988; Pratt and others, 2009a).

Electron Acceleration And Generation Of High-Brilliance X-Ray Radiation In Kilojoule, Subpicosecond Laser-Plasma Interactions, J. Ferri, X. Davoine, S. Y. Kalmykov, A. Lifschitz

Department of Physics and Astronomy: Faculty Publications

Petawatt, picosecond laser pulses offer rich opportunities in generating synchrotron x-rays. This paper concentrates on the regimes accessible with the PETAL laser, which is a part of the Laser Megajoule (LMJ) facility. We explore two physically distinct scenarios through Particle-in-Cell simulations. The first one realizes in a dense plasma, such that the period of electron Langmuir oscillations is much shorter than the pulse duration. Hallmarks of this regime are longitudinal breakup (“self-modulation”) of the picosecond-scale laser pulse and excitation of a rapidly evolving broken plasma wake. It is found that electron beams with a charge of several tens of nCcan …

Intertemporal Similarity: Discounting As A Last Resort, Jeffrey R. Stevens

Jeffrey Stevens Publications

Standard models of intertemporal choice assume that individuals discount future payoffs by integrating reward amounts and time delays to generate a discounted value. Alternative models propose that, rather than integrate across them, individuals compare within attributes (amounts and delays) to determine if differences in one attribute outweigh differences in another attribute. For instance, Leland (2002) and Rubinstein (2003) propose models that 1) compare the two reward amounts to determine whether they are similar, 2) compare the similarity of the two time delays, and then 3) make a decision based on these similarity judgments. Here, I tested discounting models against attribute-based …

Voluntary Food Sharing In Pinyon Jays: The Role Of Reciprocity And Dominance, Juan F. Duque, Jeffrey R. Stevens

Jeffrey Stevens Publications

Food sharing offers a clear example of prosocial behavior, in which one individual’s actions benefit another. Researchers have proposed a range of hypotheses that explain why food sharing may occur among unrelated individuals. Two such hypotheses, reciprocity and dominance, have been tested in many species, including fish, corvids, rats, bats, and primates, showing that (1) recipients sometimes reciprocate sharing back to previous donors and (2) dominant individuals share more than subordinates. Although primates dominate the study of prosocial behavior, active donation of food is actually quite rare in primates. In contrast, several corvid species spontaneously share food much more frequently. …

Death Penalty. Procedures. Initiative Statute.

Propositions

Changes procedures governing state court appeals and petitions challenging death penalty convictions and sentences. • Designates superior court for initial petitions and limits successive petitions. • Establishes time frame for state court death penalty review. • Requires appointed attorneys who take noncapital appeals to accept death penalty appeals. • Exempts prison officials from existing regulation process for developing execution methods. • Authorizes death row inmate transfers among California prisons. • Increases portion of condemned inmates’ wages that may be applied to victim restitution. • States other voter approved measures related to death penalty are void if this measure receives more …

Protecting Trade Secrets Under International Investment Law: What Secrets Investors Should Not Tell States, 15 J. Marshall Rev. Intell. Prop. L. 228 (2016), Daria Kim

UIC Review of Intellectual Property Law

The article addresses specifics of trade secret protection under international investment law. As a particular example, it analyzes protection of pharmaceutical regulatory data against the background of the growing public policy campaign for broader access to clinical trial data and the recent unprecedented practice of the European Medicines Agency of disclosing clinical dossiers submitted for drug marketing approval. Given the significant role of foreign direct investment in the global pharmaceutical industry and substantial, exponentially increasing costs incurred by drug originator companies in conducting clinical trials, the prospect of investor-state dispute over data disclosure does not appear purely hypothetical. The question …

Cultural Heritage & New Media: A Future For The Past, 15 J. Marshall Rev. Intell. Prop. L. 604 (2016), Ann Marie Sullivan

UIC Review of Intellectual Property Law

The application of new media to cultural heritage is consistent with the policy objectives that the copyright law of the United States stands to promote. However, the practical application of the law currently hinders these objectives, often stifling the creation and dissemination of new media works of cultural heritage. In this context, copyright law presents a problem and not a solution, a barrier and not a protection, dissuasion of creation and not encouragement and incentive. Defining the legal scope and reach of digital property and new media within the realm of art and cultural heritage law is critical for the …

Process And Reconciliation: Integrating The Duty To Consult With Environmental Assessment, Alastair Neil Craik

Osgoode Legal Studies Research Paper Series

As the duty to consult Aboriginal peoples becomes operationalized within the frameworks of government decision-making, the agencies responsible for these decisions are increasingly turning to environmental assessment (EA) processes as one of the principal vehicles for carrying out those consultations. This article explores the practical and theoretical dimensions of using EA processes to implement the duties to consult and accommodate. The relationship between EA and the duty to consult has arisen in a number of cases and a clear picture is emerging of the steps that agencies conducting EAs must carry out in order to discharge their constitutional obligations to …

Consult, Consent And Veto: International Norms And Canadian Treaties, Shin Imai

Osgoode Legal Studies Research Paper Series

Large parts of Canada, from Ontario to parts of British Columbia and north to the Northwest Territories, are covered by the “numbered treaties”, signed between First Nations and the Crown between 1871 and 1929. These treaties provide for the creation of small reserves for the Indians, and the “surrender” of the remaining tracts of land to the Crown. The land that is “surrendered” continues to be available for Indigenous hunting, fishing and harvesting activities. However, once the land is “taken up” by the provincial Crown for activities such as mining, lumbering and settlement, the treaty rights to hunt, fish and …

Online Permaculture Resources: An Evaluation Of A Selected Sample, Claire M. Luchkina

Inquiry: The University of Arkansas Undergraduate Research Journal

As a newly-emerging, sustainable approach to landscape management, permaculture seeks to integrate knowledge from several disciplines into a holistic system with emphasis on ecological and social responsibility. Online resources on permaculture appear to represent a promising direction in the movement by supplementing existing printed sources, serving to update and diversify existing content, and increasing access to permaculture information and praxis among the general public. This study evaluated a sample of online resources on permaculture using a framework of parameters reflecting website usability and content quality. Best practice for website usability, as well as diversity of information and applicability, was addressed. …

Dietary Magnesium And Copper Affect Survival Time And Neuroinflammation In Chronic Wasting Disease, Tracy A. Nichols, Terry R. Spraker, Thomas Gidlewski, Bruce Cummings, Dana Hill, Qingzhong Kong, Aru Balachandran

United States Department of Agriculture Wildlife Services: Staff Publications

Chronic wasting disease (CWD), the only known wildlife prion disease, affects deer, elk and moose. The disease is an ongoing and expanding problem in both wild and captive North American cervid populations and is difficult to control in part due to the extreme environmental persistence of prions, which can transmit disease years after initial contamination. The role of exogenous factors in CWD transmission and progression is largely unexplored. In an effort to understand the influence of environmental and dietary constituents on CWD, we collected and analyzed water and soil samples from CWD-negative and positive captive cervid facilities, as well as …