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Optimizing The Distribution Of Leg Muscles For Vertical Jumping., Jeremy D Wong, Maarten F Bobbert, Arthur J Van Soest, Paul L Gribble, Dinant A Kistemaker

Brain and Mind Institute Researchers' Publications

A goal of biomechanics and motor control is to understand the design of the human musculoskeletal system. Here we investigated human functional morphology by making predictions about the muscle volume distribution that is optimal for a specific motor task. We examined a well-studied and relatively simple human movement, vertical jumping. We investigated how high a human could jump if muscle volume were optimized for jumping, and determined how the optimal parameters improve performance. We used a four-link inverted pendulum model of human vertical jumping actuated by Hill-type muscles, that well-approximates skilled human performance. We optimized muscle volume by allowing the …

A&S Students Win First Third Peoples Choice At 3-Minute Thesis Competition, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Psychological Distress, Drug Use, Sexual Risks And Medication Adherence Among Young Hiv-Positive Black Men Who Have Sex With Men: Exposure To Community Violence Matters, Dexter R. Voisin

Faculty Scholarship

In the USA, Black males are disproportionately affected by community violence and HIV. The aim of this study was to assess whether exposures to community violence are related to psychological distress, drug use, sexual risk behaviors, and medication adherence among a sample of HIV-positive young Black men who had sex with men (YBMSM). Data are from 98 YBMSM ages 18–29 years recruited from Chicago who completed measures on demographics, exposures to community violence, psychological distress, drug use, condomless anal intercourse, and medication adherence. Rates of exposure to community violence were high and youth reported victimization and witnessing numerous types of …

Uab Continues To Be A Powerhouse In Cardiovascular Research, Adam Pope

Browse All News

No abstract provided.

Nestin-Positive/Sox2−Negative Cells Mediate Adult Neurogenesis Of Nigral Dopaminergic Neurons In Mice, Joshua E. Albright, Iva Stojkovska, Abir A. Rahman, Connor J. Brown, Brad E. Morrison

Biology Faculty Publications and Presentations

The primary clinical motor symptoms of Parkinson’s disease (PD) result from loss of dopaminergic (DA) neurons in the substantia nigra (SN). Consequently, neurogenesis of this group of neurons in the adult brain has drawn considerable interest for the purpose of harnessing endogenous neurogenerative potential as well as devising better strategies for stem cell therapy for PD. However, the existence of adult neurogenesis for DA neurons within the SN remains controversial. To overcome technical and design limitations associated with previous studies, our group has developed a novel genetic mouse model for assessing adult nigral DA neurogenesis. This system utilizes transgenic mice …

An Extract Of Urtica Dioica L. Mitigates Obesity Induced Insulin Resistance In Mice Skeletal Muscle Via Protein Phosphatase 2a (Pp2a), Diana N. Obanda, David Ribnicky, Yongmei Yu, Jacqueline Stephens, William T. Cefalu

Faculty Publications

The leaf extract of Urtica dioica L. (UT) has been reported to improve glucose homeostasis in vivo, but definitive studies on efficacy and mechanism of action are lacking. We investigated the effects of UT on obesity-induced insulin resistance in skeletal muscle. Male C57BL/6J mice were divided into three groups: low-fat diet (LFD), high-fat diet (HFD) and HFD supplemented with UT. Body weight, body composition, plasma glucose and plasma insulin were monitored. Skeletal muscle (gastrocnemius) was analyzed for insulin sensitivity, ceramide accumulation and the post translational modification and activity of protein phosphatase 2A (PP2A). PP2A is activated by ceramides and dephosphorylates …

I Am The Dream 2016, Pcom Office Of Diversity And Community Relations

Diversity and Inclusion

Program for the 2016 event I am the Dream: the Past, Present and Future at Philadelphia College of Osteopathic Medicine. Consists of the Dr. Martin Luther King, Jr. Award Ceremony and William M. King, DO '62 Award Presentation.

Mistress of Ceremonies: Megan Cleghorn, JD, MBA

Awardees: Judith A. Lightfoot, DO ‘92, FACOI; Barbara Williams-Page, DO ‘92; Yuma Iannotti Tomes, PhD, ABA; Olivia Menardy (DO ‘16); Michael Stefanowicz (DO ‘16); Jameel Shareef (DO ‘16); J. Steven Blake, DO ’89, MSc; Israel D. Benjamin (DO ‘19)

Cddo-Me Redirects Activation Of Breast Tumor Associated Macrophages, Michael S. Ball, Emilie P. Shipman, Hyunjung Kim, Karen T. Liby, Patricia A. Pioli

Dartmouth Scholarship

Tumor-associated macrophages can account for up to 50% of the tumor mass in breast cancer patients and high TAM density is associated with poor clinical prognosis. Because TAMs enhance tumor growth, development, and metastatic potential, redirection of TAM activation may have significant therapeutic benefit. Our studies in primary human macrophages and murine breast TAMs suggest that the synthetic oleanane triterpenoid CDDO-methyl ester (CDDO-Me) reprograms the activation profile of TAMs from tumor-promoting to tumor-inhibiting. We show that CDDO-Me treatment inhibits expression of IL-10 and VEGF in stimulated human M2 macrophages and TAMs but increases expression of TNF-α and IL-6. Surface expression …

The Scarlet - Volume Xcv, No. 14 (February 26, 2016), Scarlet Staff

The Scarlet (Student Newspaper) (2011-present)

The February 26, 2016 edition of The Scarlet (est. 1939), Clark University's student-run newspaper. The Scarlet is intellectually and editorially independent of the University.

Global Warning: Stereotype Threat In The Global Church, Michael Badriaki

Doctor of Ministry

The involvement of missionaries in global missions from United States to Uganda particularly through short-term missions teams is a growing reality; while the involvement of Ugandans in missions still remains mostly local and regional. Most missions groups are motivated by the biblical commission to proclaim the gospel, humanitarian and social justice causes. However, global missions Christian groups in Uganda and Christian groups from the United States of American are faced with intercultural challenges. This dissertation discuses stereotype threat which has been shown to have debilitating consequences of fear, unsettling cognitive burdens and anxiety in targeted individuals and people groups to …

February 26, 2016, The Dakota Student

The Dakota Student

No abstract provided.

Comprehensive Genetic Testing Identifies Targetable Genomic Alterations In Most Patients With Non-Small Cell Lung Cancer, Specifically Adenocarcinoma, Single Institute Investigation, Janani Vigneswaran, Yi-Hung Carol Tan, Septimiu D. Murgu, Brian M. Won, Kathryn Alexa Patton, Victoria M. Villaflor, Philip C. Hoffman, Thomas Hensing, D. Kyle Hogarth, Renuka Malik

Dartmouth Scholarship

This study reviews extensive genetic analysis in advanced non-small cell lung cancer (NSCLC) patients in order to: describe how targetable mutation genes interrelate with the genes identified as variants of unknown significance; assess the percentage of patients with a potentially targetable genetic alterations; evaluate the percentage of patients who had concurrent alterations, previously considered to be mutually exclusive; and characterize the molecular subset of KRAS. Thoracic Oncology Research Program Databases at the University of Chicago provided patient demographics, pathology, and results of genetic testing. 364 patients including 289 adenocarcinoma underwent genotype testing by various platforms such as FoundationOne, Caris Molecular …

The Transcription Factors Adr1 Or Cat8 Are Required For Rtg Pathway Activation And Evasion From Yeast Acetic Acid-Induced Programmed Cell Death In Raffinose, Zhengchang Liu, Luna Laera, Nicoletta Guaragnella, Maša Ždralević, Domenico Marzulli, Sergio Giannattasio

Biological Sciences Faculty Publications

Yeast Saccharomyces cerevisiae grown on glucose undergoes programmed cell death (PCD) induced by acetic acid (AA-PCD), but evades PCD when grown in raffinose. This is due to concomitant relief of carbon catabolite repression (CCR) and activation of mitochondrial retrograde signaling, a mitochondria-to-nucleus communication pathway causing up-regulation of various nuclear target genes, such as CIT2, encoding peroxisomal citrate synthase, dependent on the positive regulator RTG2 in response to mitochondrial dysfunction. CCR down-regulates genes mainly involved in mitochondrial respiratory metabolism. In this work, we investigated the relationships between the RTG and CCR pathways in the modulation of AA-PCD sensitivity under glucose repression …

A Soil Management Assessment Framework (Smaf) Evaluation Of Brazilian Sugarcane Expansion On Soil Quality, Maurício R. Cherubin, Douglas Karlen, André L.C. Franco, Carlos E. P. Cerri, Cássio A. Tormena, Carlos C. Cerri

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The Soil Management Assessment Framework (SMAF) was developed to evaluate impacts of land use and management practices on soil quality (SQ), but its suitability for Brazilian tropical soils was unknown. We hypothesized that SMAF would be sensitive enough to detect SQ changes associated with sugarcane (Saccharum officinarum L.) expansion for ethanol production. Field studies were performed at three sites across the south-central region of Brazil, aiming to quantify the impacts of a land use change sequence (i.e., native vegetation–pasture–sugarcane) on SQ. Eight soil indicators were individually scored using SMAF curves developed primarily for North American soils and integrated into …

2016-02-26, Board Of Regents, Murray State University

Board of Regents Meeting Minutes

No abstract provided.

Synthesis Of Crystalline, Mesoporous Metal Oxide Catalysts For Environmental And Energy Applications, Zhu Luo

Doctoral Dissertations

The main goal of this dissertation study is to develop high activity heterogeneous catalysts (metal oxide materials) for environmental and sustainable energy applications. Controlled synthesis of crystalline structures, physical,and chemical properties of the catalysts result in improved catalytic activity. Four different topics including photocatalytic remediation, hydrogen evolution, electrochemical supercapacitors, and organic synthesis applications are discussed in this thesis.

The first part presents a unique inverse micelle preparation method to synthesize mesoporous mixed phase (anatase/rutile) titanium dioxide materials. This study was conducted with the purpose of developing an inexpensive, environmentally friendly, and visible light active photocatalyst. The prepared vanadium doped mesoporous …

University Honors Program News, Georgia Southern University

Honors College: News & Publications (2008-2020)

• Adventures in Independent Journal Publishing
• Alumni Update: Andres Montes
• Focused on the Target
• Math, Measles, and a Computer Simulation
• Winning an Award, Earning a Job

United States Presidential Primaries: What You Need To Know About Each Candidate's Views On Health Care Policy And Prescription Drugs, Alicia Rohan

Browse All News

No abstract provided.

The Firece Green Fire: Vol. 6 Issue 16, Wofford College Environmental Studies Program

The Fierce Green Fire

No abstract provided.

Ucc Minutes February 25, 2016, Kutztown University Curriculum Committee

UCC Minutes

No abstract provided.

Coercion Negates Responsibility: A Case For Indirect Compelled Doxastic Coercion And Adaptive Preferences As Effects Of Practical Coercion, Rc Patterson

Theses

In part 1 of this project, I

1. define different forms of coercion;
2. outline adaptive preferences;
3. argue that indirect doxastic coercion is the unconscious element in adaptive preferences; and
4. contextualize these concepts in the black experience.

In part 2, I

1. demonstrate how certain segregation policies are a mix of direct practical coercion and indirect doxastic compelled coercion, or indoctrination;
2. In the final section I argue that, under desert theory, coercion negates responsibility.

Students Search For Guidance At Majors Fair, Gwu-Today

GWU-Today

To see all photos from the event, click here.

February 25, 2016, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Microcystic, Elongated, And Fragmented (Melf) Pattern Invasion In Ovarian Endometrioid Carcinoma: Immunohistochemical Profile And Prognostic Implications, Allison F. Goldberg, Md, Lauren Cooper, Md, D. De Cotiis, Norman G. Rosenblum, Md, Phd, Joanna Chan, Md

Department of Pathology, Anatomy, and Cell Biology Resident's Posters

BACKGROUND

•Microcystic, Elongated and Fragmented (MELF) is a well-recognized pattern of uterine endometrioid carcinoma (UEC) associated with lymphovascular space invasion and occult lymph node metastasis

•MELF in UEC may be seen with Lynch Syndrome

•MELF in UEC is hypothesized to be histologic evidence of an epithelial mesenchymal transition

•MELF pattern invasion in ovarian endometrioid carcinoma (OEC) was first described at USCAP 2015 •

Current study evaluates MELF in OEC for

•Prognostic implications

•Immunohistochemical (IHC) profile related to

•Lynch Syndrome

•Epithelial mesenchymal transition

DESIGN

•42 consecutive cases of OEC without concurrent UEC (1996-2014) evaluated by 2 pathologists

•MELF defined as at …

The Tiger Vol. 110 Issue 14 2016-02-25, Clemson University

Tiger Newspapers 2016

No abstract provided.

Biology Alum Named Dean Of University Of Michigan School Of Kinesiology, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Bacteriophage Ems9: Preliminary Genomic Description, Hallie Rae Zimmer

Honors Projects

EMS9 is a bacteriophage that was recently isolated from an Escherichia coli strain present in horse feces. Bacteriophage EMS9 consists of 98,771 base pairs that are organized into 139 predicted open reading frames (ORFs). These predicted genes potentially encode specific bacteriophage proteins. The genomic sequence of bacteriophage EMS9 is arranged intro three groups: early, middle, and late genes. Considerable homology between the ORFs of bacteriophage EMS9 and bacteriophages T5 and H8 exists. All of these bacteriophages are believed to use a rare two-step transfer mechanism to invade host cells. This annotation of the genomic sequence of EMS9 will provide a …

Daily Eastern News: Feburary 25, 2016, Eastern Illinois University

February

No abstract provided.

The Comment, February 25, 2016, Bridgewater State University

The Comment

No abstract provided.

Hawks' Herald -- Feb. 25 , 2016, Roger Williams University

Hawk's Herald

No abstract provided.